Kyle J. Norton
Scientists may have found a kitchen spice that processes bioactive ingredients for the treatment of metabolic dysfunction with no side effects, according to studies.
Metabolism is a natural chemical process of organisms, including humans with the aim to sustain- life.
According to the purposes of the bioprocess, human metabolism can be classified into the process to convert food to energy by breaking down carbohydrates, proteins, and fats to run cellular processes and eliminate nitrogenous wastes.
Metabolic dysfunction is a condition caused by any interruption of the aforementioned processes.
In other words, metabolic dysfunction induces the production of excess or a reduced amount of substances needed to stay healthy.
A metabolic disorder can be caused by genetic proposition-induced inborn errors of metabolism, or acquired by an individual in the lifetime
There are many risk factors associated with the onset of metabolic dysfunction depending on the types of disruption such as abnormal blood glucose metabolism-induced type 2 diabetes.
Diseases associated with metabolic dysfunction can be moderate or severe depending on the organs involved, including liver or respiratory failure, cancer, chronic obstructive pulmonary disease (COPD, includes emphysema and chronic bronchitis), and HIV/AIDS.
Symptoms of metabolic dysfunction are varied among individuals depending totally on the type of disorder.
Some mild conditions of metabolic dysfunction can be managed with only lifestyle change, others may require the long-term intake of certain medications accompanied by a healthy diet and moderate exercise such as diabetes.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a natural compound for the treatment of metabolic dysfunction, researchers examined the potential capacity of curcumin, contained in Curcuma longa extract (Biocurcuma™), in the attenuation of risperidone-induced metabolic dysfunction in an animal model.
The study involved 4 groups of mice that were treated once a week, for 22 weeks with an intraperitoneal injection of risperidone (Risperdal) at a dose of 12.5 mpk.
One group of mice in the risperidone-treated group was fed a diet with 0.05% Biocurcuma™ (curcumin), one of the vehicle-treated group and two other groups received the standard diet.
The curcumin treatment group inhibited the risperidone effect in reducing spontaneous motricity (motor function) but failed to impede de risperidone-induced increase in food intake.
In other words, curcumin failed to reduce de risperidone-induced weight gain and steatosis but decreased visceral adiposity stored within the abdominal cavity and decreased the risperidone-induced abnormal enlargement of the liver.
Furthermore, curcumin protected the liver enzymes associated with lipid and glucose metabolism against overexpression in the induction of metabolic dysfunction by modulating the risperidone-induced glucose intolerance and hypertriglyceridemia.
Moreover, the curcumin treatment group also showed reduced levels of markers of hepatotoxicity (ALAT, ASAT) and proinflammatory cytokines expression caused by risperidone (Risperdal).
Dr. Auger F, the lead scientist said, "These findings support that nutritional doses of curcumin contained in Curcuma longa extract are able to partially counteract the risperidone-induced metabolic dysfunction in mice".
The findings suggested that Curcuma longa extract inhibited metabolic dysfunction through a number of mechanisms involving adipocytes, pancreatic cells, hepatic stellate cells, macrophages, and muscle cells.
Taken together, turmeric and its bioactive compound curcumin may be considered functional remedies for the treatment of syndrome and diseases associated with metabolic dysfunction, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Risperidone-induced metabolic dysfunction is attenuated by Curcuma longa extract administration in mice by Auger F1,2, Martin F3,4,5,6, Pétrault O2,7, Samaillie J3,8, Hennebelle T3,8, Trabelsi MS4,5,6, Bailleul F3,8, Staels B3,4,5,6, Bordet R2, Duriez P. (PubMed)
(2) Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals by Aggarwal BB. (PubMed)
Thursday, 29 June 2023
#Healthyfood #GarlicProcesses A Strong Effect on Hypertension Control, Scientists Say
Kyle J. Norton
Scientists may have found a common kitchen spice with the potential in reducing high blood pressure quickly without including any side effects, some studies endorsed.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
High blood pressure means raising the pressure in your heart. If it stays high over time it can damage the body in many ways.
The causes of hypertension are unknown. However, researchers do know that acute hypertension is induced by daily stress.
Certain risk factors such as unhealthy lifestyle choices, physical inactivity unhealthy diet with high saturated and trans fat, refined products, processed food, and high sugar, and salt intake,...... over time cause your blood pressure to spice up chronically.
Lifestyle choices can also lead to overweight or obese, the risk factors for the early onset of hypertension.
According to the statistic, in the US, over 75 million adults or 32% have high blood pressure.
In other words, 1 in every 3 American adults has the syndrome. Sadly 44% of the mentioned adults with high blood pressure are not under control.
Uncontrol high blood pressure has long been known as a major risk factor for the development of heart disease and stroke, the leading causes of death in the United States.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects such as gastrointestinal discomforts, tiredness, weakness, headache.
Some patients who are taking hypertensive medicine over prolonged periods of time may experience symptoms of erectile dysfunction.
In severe cases, intake of antihypertensive drugs for a long term can cause dermatitis, arthritis and anemia and lupus erythematosus-like syndrome, according to the article "Adverse Effects of Antihypertensive Drugs" written by Dr. DWARD D. FREIS, M.D.
If you are currently taking any anti-high blood pressure medications, please make you that you know all the side effects.
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia.
The kitchen spice has been used popularly in traditional and Chinese medicine in treating common cold and flu, blood pressure cholesterol levels, natural antibiotics, etc.
In adult men and women, who participated in the Tehran Lipid and Glucose Study (2006-2008 to 2012-2014), intake of garlic is associated to reduce the risk of hypertension by up to 26%.
In hypertension of 80-90% of patients with excess glucocorticoid levels, allicin found in garlic attenuated dexamethasone-induced anorexia and loss of total body weight.
A randomized, placebo-controlled, clinical trial conducted on 56 CVD patients, aged 25 - 75 years old also suggested treatment with garlic-based drugs can be effective for controlling BP in CVD patients and has no interaction with other drugs that CAD patients take, after 3 months of the administration.
Dr. Takashima M the lead author at the Wakunaga Pharmaceutical Co. Ltd said, "Aged garlic extract (AGE) is effective in reducing the blood pressure of hypertensive patients,......AGE-induced the concentration-dependent vasorelaxation of isolated rat aortic rings that had been precontracted with norepinephrine"
In fact, The traditional Chinese medicine, food therapy, and hypertension control, all recommended that garlic is of the food to be used for hypertension control, according to a statistical analysis of antihypertensive foods recommended in 20 books on the application of food therapy for hypertension control.
If you can control your diet, make changes to lifestyle, maintaining an ideal weight, you could do just fine without the drugs,
Taken together, garlic may be used as preventive and controlling effects for patients with or without high blood pressure. Some researchers insisted that garlic anti hypertension effect may result from its anticoagulant property.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antihypertensive effect of allicin in dexamethasone-induced hypertensive rats by Dubey H1,2, Singh A1, Patole AM2, Tenpe CR2(PubMed)
(2) Allium vegetable intakes and the incidence of cardiovascular disease, hypertension, chronic kidney disease, and type 2 diabetes in adults: a longitudinal follow-up study by Bahadoran Z1, Mirmiran P, Momenan AA, Azizi F.(PubMed)
(3) Does Garlic Supplementation Control Blood Pressure in Patients with Severe Coronary Artery Disease? A Clinical Trial Study by Mahdavi-Roshan M1, Nasrollahzadeh J1, Mohammad Zadeh A2, Zahedmehr A3. (PubMed)
(4) Traditional Chinese Medicine, Food Therapy, and Hypertension Control: A Narrative Review of Chinese Literature by Zou P1(PubMed)
(5) The anticoagulant rivaroxaban lowers portal hypertension in cirrhotic rats mainly by deactivating hepatic stellate cells by Vilaseca M1,2, García-Calderó H1,3, Lafoz E1,2, García-Irigoyen O3,4, Avila MA3,4, Reverter JC5, Bosch J1,2,3,6, Hernández-Gea V1,3, Gracia-Sancho J1,2,3, García-Pagán JC1,2,3(PubMed)
Scientists may have found a common kitchen spice with the potential in reducing high blood pressure quickly without including any side effects, some studies endorsed.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
High blood pressure means raising the pressure in your heart. If it stays high over time it can damage the body in many ways.
The causes of hypertension are unknown. However, researchers do know that acute hypertension is induced by daily stress.
Certain risk factors such as unhealthy lifestyle choices, physical inactivity unhealthy diet with high saturated and trans fat, refined products, processed food, and high sugar, and salt intake,...... over time cause your blood pressure to spice up chronically.
Lifestyle choices can also lead to overweight or obese, the risk factors for the early onset of hypertension.
According to the statistic, in the US, over 75 million adults or 32% have high blood pressure.
In other words, 1 in every 3 American adults has the syndrome. Sadly 44% of the mentioned adults with high blood pressure are not under control.
Uncontrol high blood pressure has long been known as a major risk factor for the development of heart disease and stroke, the leading causes of death in the United States.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects such as gastrointestinal discomforts, tiredness, weakness, headache.
Some patients who are taking hypertensive medicine over prolonged periods of time may experience symptoms of erectile dysfunction.
In severe cases, intake of antihypertensive drugs for a long term can cause dermatitis, arthritis and anemia and lupus erythematosus-like syndrome, according to the article "Adverse Effects of Antihypertensive Drugs" written by Dr. DWARD D. FREIS, M.D.
If you are currently taking any anti-high blood pressure medications, please make you that you know all the side effects.
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia.
The kitchen spice has been used popularly in traditional and Chinese medicine in treating common cold and flu, blood pressure cholesterol levels, natural antibiotics, etc.
In adult men and women, who participated in the Tehran Lipid and Glucose Study (2006-2008 to 2012-2014), intake of garlic is associated to reduce the risk of hypertension by up to 26%.
In hypertension of 80-90% of patients with excess glucocorticoid levels, allicin found in garlic attenuated dexamethasone-induced anorexia and loss of total body weight.
A randomized, placebo-controlled, clinical trial conducted on 56 CVD patients, aged 25 - 75 years old also suggested treatment with garlic-based drugs can be effective for controlling BP in CVD patients and has no interaction with other drugs that CAD patients take, after 3 months of the administration.
Dr. Takashima M the lead author at the Wakunaga Pharmaceutical Co. Ltd said, "Aged garlic extract (AGE) is effective in reducing the blood pressure of hypertensive patients,......AGE-induced the concentration-dependent vasorelaxation of isolated rat aortic rings that had been precontracted with norepinephrine"
In fact, The traditional Chinese medicine, food therapy, and hypertension control, all recommended that garlic is of the food to be used for hypertension control, according to a statistical analysis of antihypertensive foods recommended in 20 books on the application of food therapy for hypertension control.
If you can control your diet, make changes to lifestyle, maintaining an ideal weight, you could do just fine without the drugs,
Taken together, garlic may be used as preventive and controlling effects for patients with or without high blood pressure. Some researchers insisted that garlic anti hypertension effect may result from its anticoagulant property.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antihypertensive effect of allicin in dexamethasone-induced hypertensive rats by Dubey H1,2, Singh A1, Patole AM2, Tenpe CR2(PubMed)
(2) Allium vegetable intakes and the incidence of cardiovascular disease, hypertension, chronic kidney disease, and type 2 diabetes in adults: a longitudinal follow-up study by Bahadoran Z1, Mirmiran P, Momenan AA, Azizi F.(PubMed)
(3) Does Garlic Supplementation Control Blood Pressure in Patients with Severe Coronary Artery Disease? A Clinical Trial Study by Mahdavi-Roshan M1, Nasrollahzadeh J1, Mohammad Zadeh A2, Zahedmehr A3. (PubMed)
(4) Traditional Chinese Medicine, Food Therapy, and Hypertension Control: A Narrative Review of Chinese Literature by Zou P1(PubMed)
(5) The anticoagulant rivaroxaban lowers portal hypertension in cirrhotic rats mainly by deactivating hepatic stellate cells by Vilaseca M1,2, García-Calderó H1,3, Lafoz E1,2, García-Irigoyen O3,4, Avila MA3,4, Reverter JC5, Bosch J1,2,3,6, Hernández-Gea V1,3, Gracia-Sancho J1,2,3, García-Pagán JC1,2,3(PubMed)
#Driedpowdered Fruits of Eggplant Improve Blood Cholesterol, According to Clinical Trials
Kyle J. Norton
Eggplant may process a significant effect in decreasing the risk and onset of abnormally high blood cholesterol, some scientists suggested.
Cholesterol, the waxy substance produced by the liver or intake from dietary sources plays an important role in the building of the cell walls, producing steroid hormones and promoting the digestive function in food digestion.
However, high levels of blood cholesterol can weaken the arterial wall and block the blood flow in the arteries, leading to a substantially increased risk of heart disease and stroke.
The ratio of total cholesterol is 4/1, any number that is considered within the healthy range. The lower of the ratio is an indication that you have a higher than normal amount of high-density lipoprotein (HDL), which is essential to remove blood cholesterol from the blood back to the liver, leading to less low-density lipoprotein (LDL) in the initiation of cardiovascular diseases.
.
The below table Classification of cholesterol levels, provided by Dr.Michael Tanner and Dr. Nate Link the lead author at the New York University School of Medicine and Bellevue Hospital Center New York,
Cholesterol, mmol/L (mg/dL)ClassificationTotal
<5.17 (<200) Desirable
5.17-6.19 (200-239) Borderline
≥6.20 (≥240) High
HDL-C Classification
<1.00 (<40) Low
≥1.43 (≥60) High
US prevalence (%) of high total cholesterol levels (≥6.21 mmol/L [≥240 mg/dL]) and coronary artery disease (NHANES III: 1988-1991)1
Age, yrHigh cholesterol levelCoronary artery disease
MenWomenMenWomen20-34 9 8 2 3
35-44 18 11 3 4
45-54 25 23 9 6
55-64 25 37 17 12
65-74 22 39 17 11
≥75 14 32 23 16
Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.
The plant has been cultivated in southern and eastern Asia since prehistory. It is famous for its deep purple and the best eggplant can be found from August through October when it is in season.
Chemical constituents of eggplant include sterols (i.e. typical plant sterols, androstane, pregnane and cholestane derivatives, steroidal alkaloids and sapogenins), phytosterols, triterpenes, δ-amyrin, Chlorogenic acid, Nasunin, and other Polyphenolic compounds.
In the study to reaffirm the Eggplant (Solanum melongena) consumed extensively in Brazil may have a strong effect in reducing the serum cholesterol researchers at the Instituto de Ciências Biológicas conducted an evaluation to test the plant cholesterol metabolism and hypocholesterolemic effect
In the total of 38 hypercholesterolemic human volunteers ingesting S. melongena infusion for five weeks, 38 hypercholesterolemic subjects were given either S. melongena infusion (N = 19) or placebo (N = 19) and participated in two clinical experiments in which the effect of S. melongena infusion was studied with (N = 16) or without (N = 38) dietary orientation.
S. melongena infusion significantly reduced the blood levels of total and LDL cholesterol and of apolipoprotein B.
After dietary orientation, no intra- or intergroup differences were seen for any of the parameters analyzed.
The results suggest that S. melongena infusion had a modest and transitory effect, which was not different from that obtained with standard orientation for dyslipidemia patients (diet and physical activities).
Dried powdered fruits of eggplant (Solanum melongena) was tested in a double-blind placebo-controlled study of the effectiveness of oral Solanum melongena (SM) consisted of 41 hyperlipidemic volunteers allocated to active treatment (n= 21) or placebo (n= 20).
Each volunteer received two capsules containing SM (450 mg) or placebo (450 mg) twice daily and was followed monthly. The dose of SM used corresponds to that given to treat hyperlipidemia in Brazil.
After 3 months, serum total cholesterol, LDL-c, and LDL-c/HDL-c decreased (p<0.05) in the group treated with SM.
Dr. Silva GE, the lead author wrote in the final report of the study, " SM, at least in the form commercialized in Brazil (dried powdered fruits), require further clinical trials before being recommended to treat hyperlipidemia".
Taken together, eggplant may be considered a functional food for the prevention and adjunct therapy for the treatment of high blood cholesterol with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension by Kwon YI1, Apostolidis E, Shetty K.(PubMed)
(2) Eggplant (Solanum melongena) infusion has a modest and transitory effect on hypercholesterolemic subjects by Guimarães PR1, Galvão AM, Batista CM, Azevedo GS, Oliveira RD, Lamounier RP, Freire N, Barros AM, Sakurai E, Oliveira JP, Vieira EC, Alvarez-Leite JI. (PubMed)
(3) [Absence of hypolipidemic effect of Solanum melongena L. (eggplant) on hyperlipidemic patients].[Article in Portuguese] by Silva GE1, Takahashi MH, Eik Filho W, Albino CC, Tasim GE, Serri Lde A, Assef AH, Cortez DA, Bazotte RB.(PubMed)
(4) Hyperlipidemia: Part 1. Evaluation and dietary management by Michael Tanner1 and Nate Link.(PMC)
Eggplant may process a significant effect in decreasing the risk and onset of abnormally high blood cholesterol, some scientists suggested.
Cholesterol, the waxy substance produced by the liver or intake from dietary sources plays an important role in the building of the cell walls, producing steroid hormones and promoting the digestive function in food digestion.
However, high levels of blood cholesterol can weaken the arterial wall and block the blood flow in the arteries, leading to a substantially increased risk of heart disease and stroke.
The ratio of total cholesterol is 4/1, any number that is considered within the healthy range. The lower of the ratio is an indication that you have a higher than normal amount of high-density lipoprotein (HDL), which is essential to remove blood cholesterol from the blood back to the liver, leading to less low-density lipoprotein (LDL) in the initiation of cardiovascular diseases.
.
The below table Classification of cholesterol levels, provided by Dr.Michael Tanner and Dr. Nate Link the lead author at the New York University School of Medicine and Bellevue Hospital Center New York,
Cholesterol, mmol/L (mg/dL)ClassificationTotal
<5.17 (<200) Desirable
5.17-6.19 (200-239) Borderline
≥6.20 (≥240) High
HDL-C Classification
<1.00 (<40) Low
≥1.43 (≥60) High
US prevalence (%) of high total cholesterol levels (≥6.21 mmol/L [≥240 mg/dL]) and coronary artery disease (NHANES III: 1988-1991)1
Age, yrHigh cholesterol levelCoronary artery disease
MenWomenMenWomen20-34 9 8 2 3
35-44 18 11 3 4
45-54 25 23 9 6
55-64 25 37 17 12
65-74 22 39 17 11
≥75 14 32 23 16
Eggplant is a species of S. melongena, belonging to the family Solanaceae and native to India.
The plant has been cultivated in southern and eastern Asia since prehistory. It is famous for its deep purple and the best eggplant can be found from August through October when it is in season.
Chemical constituents of eggplant include sterols (i.e. typical plant sterols, androstane, pregnane and cholestane derivatives, steroidal alkaloids and sapogenins), phytosterols, triterpenes, δ-amyrin, Chlorogenic acid, Nasunin, and other Polyphenolic compounds.
In the study to reaffirm the Eggplant (Solanum melongena) consumed extensively in Brazil may have a strong effect in reducing the serum cholesterol researchers at the Instituto de Ciências Biológicas conducted an evaluation to test the plant cholesterol metabolism and hypocholesterolemic effect
In the total of 38 hypercholesterolemic human volunteers ingesting S. melongena infusion for five weeks, 38 hypercholesterolemic subjects were given either S. melongena infusion (N = 19) or placebo (N = 19) and participated in two clinical experiments in which the effect of S. melongena infusion was studied with (N = 16) or without (N = 38) dietary orientation.
S. melongena infusion significantly reduced the blood levels of total and LDL cholesterol and of apolipoprotein B.
After dietary orientation, no intra- or intergroup differences were seen for any of the parameters analyzed.
The results suggest that S. melongena infusion had a modest and transitory effect, which was not different from that obtained with standard orientation for dyslipidemia patients (diet and physical activities).
Dried powdered fruits of eggplant (Solanum melongena) was tested in a double-blind placebo-controlled study of the effectiveness of oral Solanum melongena (SM) consisted of 41 hyperlipidemic volunteers allocated to active treatment (n= 21) or placebo (n= 20).
Each volunteer received two capsules containing SM (450 mg) or placebo (450 mg) twice daily and was followed monthly. The dose of SM used corresponds to that given to treat hyperlipidemia in Brazil.
After 3 months, serum total cholesterol, LDL-c, and LDL-c/HDL-c decreased (p<0.05) in the group treated with SM.
Dr. Silva GE, the lead author wrote in the final report of the study, " SM, at least in the form commercialized in Brazil (dried powdered fruits), require further clinical trials before being recommended to treat hyperlipidemia".
Taken together, eggplant may be considered a functional food for the prevention and adjunct therapy for the treatment of high blood cholesterol with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension by Kwon YI1, Apostolidis E, Shetty K.(PubMed)
(2) Eggplant (Solanum melongena) infusion has a modest and transitory effect on hypercholesterolemic subjects by Guimarães PR1, Galvão AM, Batista CM, Azevedo GS, Oliveira RD, Lamounier RP, Freire N, Barros AM, Sakurai E, Oliveira JP, Vieira EC, Alvarez-Leite JI. (PubMed)
(3) [Absence of hypolipidemic effect of Solanum melongena L. (eggplant) on hyperlipidemic patients].[Article in Portuguese] by Silva GE1, Takahashi MH, Eik Filho W, Albino CC, Tasim GE, Serri Lde A, Assef AH, Cortez DA, Bazotte RB.(PubMed)
(4) Hyperlipidemia: Part 1. Evaluation and dietary management by Michael Tanner1 and Nate Link.(PMC)
Intake of #Greentea Regularly Improves Psychological Functions Such As Attention., Work Performance and Creativity, Researchers Say
Kyle J. Norton
Green tea may have a potential and positive effect in treating a mood disorder, some scientists suggested.
Mood disorder is a psychological condition characterized by an elevated mood, including mania or hypomania. In other words, a syndrome is a group of mental illnesses that can affect how a person feels and think of him/herself and people in public life.
A mood disorder can be classified into depression, dysthymic disorder,... and bipolar disorder depending on the symptoms of expression.
The condition not only affects the personal life of the patient but also causes psychological and financial burdens to the immediate family members as the condition can only get worse over time.
According to the statistic in 2017, over 2.6 million Canadian age 12 and over were diagnosed with mood disorders, affecting over 8% of the general population. Sadly, about one in seven Canadians will experience a mood disorder at some point in their life.
The exact causes of mood disorders are unknown, however, there are some underlying factors that can elevate the risk of the condition, including family history, previous mood disorder, depression, certain medical conditions, and long-term use of some medication.
Symptoms of mood disorders are totally depending on the type of the syndrome. If you are experiencing symptoms of feelings of hopelessness, long-term trouble sleeping or daytime sleepiness, poor concentration, and trouble concentrating or making decisions accompanied by physical symptoms of fatigue or low energy, you may have mood disorders. Please check with your doctor to rule out the possibility.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.
In the concerns of the widespread mental disorders, researchers at Elsevier GmbH.lauched an investigation to examine the effects of green tea or green tea extracts, l-theanine and epigallocatechin gallate both components of green tea on general neuropsychology, on the sub-category cognition and on brain functions in humans.
By searching the database of medical literature in PubMed for qualified studies that are satisfied the guidelines and criteria set by the PRISMA statement.
Out of 21 selected studies, 4 were randomized controlled trials, 12 were cross-over studies (both assessed with an adapted version of the DELPHI list), 4 were cross-sectional studies and one was a cohort study (both assessed with an adapted version of the Newcastle-Ottawa assessment scale).
After assessing the results of all studies, researchers found that injection of green tea exerts a significant effect on psychopathological symptoms (e.g. reduction of anxiety), cognition (e.g. benefits in memory and attention), and brain function (e.g. activation of working memory seen in functional MRI).
Further analysis also suggested that the effects of green tea may be attributed to the combined influence of both caffeine and l-theanine, as separate administration of either substance is found to have a lesser impact.
Moreover, in the systematic review and meta-analysis conducted on 11 randomized placebo-controlled human studies of acute effects of tea constituents L-theanine and epigallocatechin gallate, administered alone or in combination with caffeine, on cognitive function and mood, researchers discovered that* Combined caffeine and L-theanine demonstrated some moderate effects in the first 2 hours postdose, on ladder alertness, attentional switching accuracy, and, to a lesser extent, some unisensory and multisensory attentional outcomes.
* Caffeine and L-theanine doses revealed trends toward greater change in effect size for caffeine dose than for L-theanine dose, particularly during the first-hour post-dose.
Additionally, in the study to evaluate whether the tea has any effect on mood and performance benefits, such as relaxation and concentration, researchers at From Unilever Research and Development also conducted an extensive search of studies with consistent evidence for improved attention.
In the final report, researchers concluded after taking into account co and confounders
* Tea consumption also consistently improved self-reported alertness and arousal, whereas effects on pleasure or relaxation were less consistent.
* Intake of tea regularly has a strong impact on psychological functions such as work performance and creativity.
The findings suggested that moderate green tea consumption regularly and daily has significant acute benefits in both mood and performance in real-life situations.
Taken together, there is no doubt that green tea containing a number of highly bioactive compounds such as caffeine, l-theanine, and epigallocatechin gallate may be considered a functional food to protect brain functioning against the onset of mood disorders.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea effects on cognition, mood, and human brain function: A systematic review by Mancini E1, Beglinger C2, Drewe J2, Zanchi D1, Lang UE1, Borgwardt S3(PubMed)
(2) Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis by Camfield DA1, Stough C, Farrimond J, Scholey AB(PubMed)
(3) Acute effects of tea consumption on attention and mood by Einöther SJ1, Martens VE. (PubMed)
Green tea may have a potential and positive effect in treating a mood disorder, some scientists suggested.
Mood disorder is a psychological condition characterized by an elevated mood, including mania or hypomania. In other words, a syndrome is a group of mental illnesses that can affect how a person feels and think of him/herself and people in public life.
A mood disorder can be classified into depression, dysthymic disorder,... and bipolar disorder depending on the symptoms of expression.
The condition not only affects the personal life of the patient but also causes psychological and financial burdens to the immediate family members as the condition can only get worse over time.
According to the statistic in 2017, over 2.6 million Canadian age 12 and over were diagnosed with mood disorders, affecting over 8% of the general population. Sadly, about one in seven Canadians will experience a mood disorder at some point in their life.
The exact causes of mood disorders are unknown, however, there are some underlying factors that can elevate the risk of the condition, including family history, previous mood disorder, depression, certain medical conditions, and long-term use of some medication.
Symptoms of mood disorders are totally depending on the type of the syndrome. If you are experiencing symptoms of feelings of hopelessness, long-term trouble sleeping or daytime sleepiness, poor concentration, and trouble concentrating or making decisions accompanied by physical symptoms of fatigue or low energy, you may have mood disorders. Please check with your doctor to rule out the possibility.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.
In the concerns of the widespread mental disorders, researchers at Elsevier GmbH.lauched an investigation to examine the effects of green tea or green tea extracts, l-theanine and epigallocatechin gallate both components of green tea on general neuropsychology, on the sub-category cognition and on brain functions in humans.
By searching the database of medical literature in PubMed for qualified studies that are satisfied the guidelines and criteria set by the PRISMA statement.
Out of 21 selected studies, 4 were randomized controlled trials, 12 were cross-over studies (both assessed with an adapted version of the DELPHI list), 4 were cross-sectional studies and one was a cohort study (both assessed with an adapted version of the Newcastle-Ottawa assessment scale).
After assessing the results of all studies, researchers found that injection of green tea exerts a significant effect on psychopathological symptoms (e.g. reduction of anxiety), cognition (e.g. benefits in memory and attention), and brain function (e.g. activation of working memory seen in functional MRI).
Further analysis also suggested that the effects of green tea may be attributed to the combined influence of both caffeine and l-theanine, as separate administration of either substance is found to have a lesser impact.
Moreover, in the systematic review and meta-analysis conducted on 11 randomized placebo-controlled human studies of acute effects of tea constituents L-theanine and epigallocatechin gallate, administered alone or in combination with caffeine, on cognitive function and mood, researchers discovered that* Combined caffeine and L-theanine demonstrated some moderate effects in the first 2 hours postdose, on ladder alertness, attentional switching accuracy, and, to a lesser extent, some unisensory and multisensory attentional outcomes.
* Caffeine and L-theanine doses revealed trends toward greater change in effect size for caffeine dose than for L-theanine dose, particularly during the first-hour post-dose.
Additionally, in the study to evaluate whether the tea has any effect on mood and performance benefits, such as relaxation and concentration, researchers at From Unilever Research and Development also conducted an extensive search of studies with consistent evidence for improved attention.
In the final report, researchers concluded after taking into account co and confounders
* Tea consumption also consistently improved self-reported alertness and arousal, whereas effects on pleasure or relaxation were less consistent.
* Intake of tea regularly has a strong impact on psychological functions such as work performance and creativity.
The findings suggested that moderate green tea consumption regularly and daily has significant acute benefits in both mood and performance in real-life situations.
Taken together, there is no doubt that green tea containing a number of highly bioactive compounds such as caffeine, l-theanine, and epigallocatechin gallate may be considered a functional food to protect brain functioning against the onset of mood disorders.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea effects on cognition, mood, and human brain function: A systematic review by Mancini E1, Beglinger C2, Drewe J2, Zanchi D1, Lang UE1, Borgwardt S3(PubMed)
(2) Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis by Camfield DA1, Stough C, Farrimond J, Scholey AB(PubMed)
(3) Acute effects of tea consumption on attention and mood by Einöther SJ1, Martens VE. (PubMed)
Wednesday, 28 June 2023
#WhiteButtonMushroom Shows a Protecttive Effect on Liver by Inhibiting Liver's Fat Accumulation, Researchers Reveal
Kyle J. Norton
White button mushrooms may have a protective effect against the onset and treatment of nonalcoholic liver disease, some scientists suggested.
Fatty liver or hepatic steatosis is a disease caused by the buildup of fat in the liver. If the fat in your liver is over 5 percent proportional to the liver cells, you are considered to have the early stage of fatty liver disease.
According to the American liver foundation, fatty liver is the most common disease in the US, affecting over affecting around 25 % of the population. The disease is most common in the age group between 40 and 60.
The common diseases associated with the onset of nonalcoholic fatty liver disease include obesity hyperlipidemia, or high levels of fats in the blood, especially high triglycerides, diabetes, and genetic inheritance.
However, some researchers also found that long-term use of certain medications is the prevalent risk factor for fatty liver such as rapid weight loss side effects of certain medications, including methotrexate (Trexall), tamoxifen (Nolvadex), amiodarone (Pacerone), and valproic acid (Depakote).
Can the nonalcoholic fatty liver disease be prevented? Dr. William Nseir, the lead author in the study " Role of diet and lifestyle changes in nonalcoholic fatty liver disease", wrote, "There is no drug therapy that can be formulated for treating NAFLD. A combination of dietary modifications and increased physical activity remains the mainstay of NAFLD management" and
"NAFLD patients, whether obese or not, should be educated that a healthy diet and physical activity have benefits beyond weight reduction".
The result suggested that if you have followed a healthy diet high in fruits and vegetables, whole grains, and low in saturated and trans fat, red meat, and processed food and lifestyle accompanied by moderate exercise, your risk of nonalcoholic fatty liver disease is close to zero.
If you are experiencing the symptoms of a persistently enlarged fluid-filled abdomen, jaundice of the skin and eyes, confusion, and abnormal bleeding, please check with your doctor to rule out the possibility of fatty liver disease.
Mushroom is a standard name for white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source,
It is the genus A. Muscaria and belongs to the family Amanitaceae and has been cultivated in many cultures worldwide for food and health benefits.
The chemical constituents of white button mushrooms include
Astraodorol, Psilocybin, Lectin, adustin, ribonuclease, nicotine, 2-hydroxy-4-methoxy-6-methylbenzoic acid, orsellinic acid, melleolide, ergosterol, genistein, daidzein, daucosterol, genistin, uracil, and D-mannitol.
In the concerns of low estrogen production in the risk of nonalcoholic fatty liver disease in menopause women, researchers at the cellular team at the Beckman Research Institute of the City of Hope launched an investigation to examine the effects of white mushrooms in the groups of ovariectomized mice (a model of postmenopausal women).
Selected OVX mice were fed a high-fat diet supplemented with WBM powder before injection of white button mushroom to induce fatty disease pattern.
Application of white button mushroom (WBM) exerted a significant protective effect against liver steatosis in ovariectomized (OVX) mice.
As dietary WBM intake significantly lowered liver weight and hepatic injury markers in OVX mice.
The pathological examination also suggested that WBM lowers fat accumulation in tissue in the livers of mice.
Furthermore, the glucose clearance ability of tested mice also improved substantially compared to the untreated mice group.
According to the microarray analysis, genes associated with the fatty acid biosynthesis pathway, particularly the genes for fatty acid synthetase (Fas), a major determinant of the maximal hepatic capacity to generate fatty acids by de novo lipogenesis and fatty acid elongase 6 (Elovl6) which plays a key role in fat synthesis were down-regulated (reduced function).
Additionally, in vivo, the down-regulation of the expression of FAS and ELOVL6 in the HepG2 cell line by WBM extract was attributed to the inhibition of Liver X receptor (LXR) signaling and its downstream transcriptional factor SREBP1c.
Where Liver X receptors (LXRs) are important regulators of cholesterol and fatty acid and SREBP-1c is associated with fatty liver and increased visceral fat mass.
The finding indicated that WBM is protective against hepatic steatosis and NAFLD in OVX mice as a model for postmenopausal women.
The study was published on October 25 by the US National Library of Medicine and National Institutes of Health. You can view the publication by clicking the link in the resources,
Taken together, white button mushrooms may be considered a functional food for the prevention and treatment of nonalcoholic fatty liver disease.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(a) [Chemical constituents from fungus Armillaria mellea]. by [Article in Chinese] by Yuan XL1, Yan LH, Zhang QW, Wang ZM.(PubMed)
(1) Protective effects of white button mushroom (Agaricus bisporus) against hepatic steatosis in ovariectomized mice as a model of postmenopausal women by Kanaya N1, Kubo M, Liu Z, Chu P, Wang C, Yuan YC, Chen S.(PubMed)
(2) Role of diet and lifestyle changes in nonalcoholic fatty liver disease by William Nseir, Elias Hellou, and Nimer Assy. (PubMed)
White button mushrooms may have a protective effect against the onset and treatment of nonalcoholic liver disease, some scientists suggested.
Fatty liver or hepatic steatosis is a disease caused by the buildup of fat in the liver. If the fat in your liver is over 5 percent proportional to the liver cells, you are considered to have the early stage of fatty liver disease.
According to the American liver foundation, fatty liver is the most common disease in the US, affecting over affecting around 25 % of the population. The disease is most common in the age group between 40 and 60.
The common diseases associated with the onset of nonalcoholic fatty liver disease include obesity hyperlipidemia, or high levels of fats in the blood, especially high triglycerides, diabetes, and genetic inheritance.
However, some researchers also found that long-term use of certain medications is the prevalent risk factor for fatty liver such as rapid weight loss side effects of certain medications, including methotrexate (Trexall), tamoxifen (Nolvadex), amiodarone (Pacerone), and valproic acid (Depakote).
Can the nonalcoholic fatty liver disease be prevented? Dr. William Nseir, the lead author in the study " Role of diet and lifestyle changes in nonalcoholic fatty liver disease", wrote, "There is no drug therapy that can be formulated for treating NAFLD. A combination of dietary modifications and increased physical activity remains the mainstay of NAFLD management" and
"NAFLD patients, whether obese or not, should be educated that a healthy diet and physical activity have benefits beyond weight reduction".
The result suggested that if you have followed a healthy diet high in fruits and vegetables, whole grains, and low in saturated and trans fat, red meat, and processed food and lifestyle accompanied by moderate exercise, your risk of nonalcoholic fatty liver disease is close to zero.
If you are experiencing the symptoms of a persistently enlarged fluid-filled abdomen, jaundice of the skin and eyes, confusion, and abnormal bleeding, please check with your doctor to rule out the possibility of fatty liver disease.
Mushroom is a standard name for white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source,
It is the genus A. Muscaria and belongs to the family Amanitaceae and has been cultivated in many cultures worldwide for food and health benefits.
The chemical constituents of white button mushrooms include
Astraodorol, Psilocybin, Lectin, adustin, ribonuclease, nicotine, 2-hydroxy-4-methoxy-6-methylbenzoic acid, orsellinic acid, melleolide, ergosterol, genistein, daidzein, daucosterol, genistin, uracil, and D-mannitol.
In the concerns of low estrogen production in the risk of nonalcoholic fatty liver disease in menopause women, researchers at the cellular team at the Beckman Research Institute of the City of Hope launched an investigation to examine the effects of white mushrooms in the groups of ovariectomized mice (a model of postmenopausal women).
Selected OVX mice were fed a high-fat diet supplemented with WBM powder before injection of white button mushroom to induce fatty disease pattern.
Application of white button mushroom (WBM) exerted a significant protective effect against liver steatosis in ovariectomized (OVX) mice.
As dietary WBM intake significantly lowered liver weight and hepatic injury markers in OVX mice.
The pathological examination also suggested that WBM lowers fat accumulation in tissue in the livers of mice.
Furthermore, the glucose clearance ability of tested mice also improved substantially compared to the untreated mice group.
According to the microarray analysis, genes associated with the fatty acid biosynthesis pathway, particularly the genes for fatty acid synthetase (Fas), a major determinant of the maximal hepatic capacity to generate fatty acids by de novo lipogenesis and fatty acid elongase 6 (Elovl6) which plays a key role in fat synthesis were down-regulated (reduced function).
Additionally, in vivo, the down-regulation of the expression of FAS and ELOVL6 in the HepG2 cell line by WBM extract was attributed to the inhibition of Liver X receptor (LXR) signaling and its downstream transcriptional factor SREBP1c.
Where Liver X receptors (LXRs) are important regulators of cholesterol and fatty acid and SREBP-1c is associated with fatty liver and increased visceral fat mass.
The finding indicated that WBM is protective against hepatic steatosis and NAFLD in OVX mice as a model for postmenopausal women.
The study was published on October 25 by the US National Library of Medicine and National Institutes of Health. You can view the publication by clicking the link in the resources,
Taken together, white button mushrooms may be considered a functional food for the prevention and treatment of nonalcoholic fatty liver disease.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(a) [Chemical constituents from fungus Armillaria mellea]. by [Article in Chinese] by Yuan XL1, Yan LH, Zhang QW, Wang ZM.(PubMed)
(1) Protective effects of white button mushroom (Agaricus bisporus) against hepatic steatosis in ovariectomized mice as a model of postmenopausal women by Kanaya N1, Kubo M, Liu Z, Chu P, Wang C, Yuan YC, Chen S.(PubMed)
(2) Role of diet and lifestyle changes in nonalcoholic fatty liver disease by William Nseir, Elias Hellou, and Nimer Assy. (PubMed)
Banana's Flower and Pseudostem Inhibit Siabetic Symptoms (Hyperglycemia, Polyuria, Polyphagia, Polydipsia, Urine Sugar, and BodyWeight) in Vivos
Kyle J. Norton
Unripe bananas may be considered functional for the prevention and treatment of diabetes, some scientists suggested.
Diabetes is a medical and condition characterized by insufficient insulin entering the bloodstream to regulate the glucose as the result of either cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes is also caused by allergic reactions of cells in the immune system or immune
system mistakenly attacks the cells which produce insulin, leading to insulin resistance.
The death of beta cells in the pancreas is triggered by the massive overproduction of short strands of ribonucleic acid, known as microRNA (miR) 200. These results suggested that blocking miR-200 may guarantee the survival of beta cells, even ones under extreme stress.
In the case of the pancreas clogged up with fat accumulation, some researchers found that losing less than one gram of that fat through weight loss reverses diabetes.
Professor Taylor of Newcastle University said, “So if you ask how much weight you need to lose to make your diabetes go away, the answer is one gram! But that gram needs to be far from the pancreas. At present, the only way we have to achieve this is by calorie restriction by any means – whether by diet or an operation.
”In patients who had started with Type 2 diabetes, fat levels in the pancreas (pancreatic triglyceride) decreased by 1.2% over the 8 weeks. Very exact methods were needed to be able to measure this and a new method using a special MRI scan was developed. With an average pancreas for a person with Type 2 diabetes having a volume of 50 ml, this is the equivalent of around 0.6 grams of fat.
According to the study by ETH Zurich and the International Diabetes Foundation, there are over 380 million diabetics around the world. Approximately, by the year 2030, over half a billion people will be suffering from type 2 diabetes.
Banana is the common name of a genus of tropical herbaceous plants. It can grow from 3 to 9 m and belongs to the family of the lily and the orchid.
In the study to reaffirm the traditional use of bananas for the treatment of diabetes in India, researchers at the University College of Medical Sciences, Dilshad Garden launched an investigation to assess the antidiabetic and antihyperlipidemic effects of the stem of the banana. In the experiment, diabetes was induced in rats by streptozotocin injection (45 mg/kg, i.p.). Diabetic rats were treated for 2 weeks with different doses of lyophilized stem juice of banana. (25, 50, and 100 mg/kg) to select the most effective dose.
* The most effective dose of lyophilized stem juice of M. sapientum Linn (Banana) was 50 mg/kg.
* The four weeks of treatment with this dose resulted in significant decreases in fasting and postprandial plasma glucose (FPG, PPG) levels.
* Serum insulin increased (P < 0.05) whereas HbA1c decreased (P < 0.05).
* Diabetes-induced changes to the lipid profile, muscle and liver glycogen, and enzyme activity (i.e. glucokinase, glucose-6-phosphatase, and HMG-CoA reductase) were restored near to normal levels by the application of banana.
These results suggested that the lyophilized stem juice of banana (M. sapientum Linn) exhibits antidiabetic and antihyperlipidemic effects.
Furthermore, in the study to find out the mechanism of the hypoglycemic effect of ethanol extract of banana pseudostem (EE) researchers suggested
* The ethanol extract from the banana significantly inhibited mammalian intestinal α-glucosidases and yeast α-glucosidase.
* Oral administration (100-200 mg kg(-1) body weight) of EE significantly suppressed the maltose/glucose-induced postprandial plasma glucose elevation and wielded an antihyperglycaemic effect in normal and alloxan-induced diabetic rats.
Dr. Ramu R, the lead scientist said, "EE might exert an anti-diabetic effect by inhibition of α-glucosidases from the intestine, in turn suppressing the carbohydrate absorption into the bloodstream. Hence the results extend a foundation for the future prospects of the food-derived enzyme inhibitors in the treatment of diabetes".
Additionally, according to the Central Food Technological Research Institute, banana flowers, and pseudostem have a low glycemic index and a high content of dietary fiber and antioxidants.
Application of the flower and pseudostem showed to inhibit diabetic symptoms like hyperglycemia, polyuria, polyphagia, polydipsia, urine sugar, and body weight in the rat model.
Taken together, unripe bananas may be used as a functional food for the prevention and combined with primary therapy for the treatment of diabetes in humans, depending on the confirmation of further data collection from the large example size and multi-center studies.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Antidiabetic and antihyperlipidemic effects of the stem of Musasapientum Linn. in streptozotocin-induced diabetic rats by Dikshit P1, Shukla K, Tyagi MK, Garg P, Gambhir JK, Shukla R.(PubMed)
(2) Investigation of antihyperglycaemic activity of banana (Musa sp. var. Nanjangud rasa bale) pseudostem in normal and diabetic rats by Ramu R1, Shirahatti PS, Zameer F, Nagendra Prasad MN. (PubMed).
(3) Beneficial effects of banana (Musa sp. var. elakki bale) flower and pseudostem on hyperglycemia and advanced glycation end-products (AGEs) in streptozotocin-induced diabetic rats by Bhaskar JJ1, Shobha MS, Sambaiah K, Salimath PV. (PubMed)
(4) The life and death of beta cells by ETH Zurich
(5) Type 2 diabetes reversed by losing fat from the pancreas by New Castle University
Unripe bananas may be considered functional for the prevention and treatment of diabetes, some scientists suggested.
Diabetes is a medical and condition characterized by insufficient insulin entering the bloodstream to regulate the glucose as the result of either cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes is also caused by allergic reactions of cells in the immune system or immune
system mistakenly attacks the cells which produce insulin, leading to insulin resistance.
The death of beta cells in the pancreas is triggered by the massive overproduction of short strands of ribonucleic acid, known as microRNA (miR) 200. These results suggested that blocking miR-200 may guarantee the survival of beta cells, even ones under extreme stress.
In the case of the pancreas clogged up with fat accumulation, some researchers found that losing less than one gram of that fat through weight loss reverses diabetes.
Professor Taylor of Newcastle University said, “So if you ask how much weight you need to lose to make your diabetes go away, the answer is one gram! But that gram needs to be far from the pancreas. At present, the only way we have to achieve this is by calorie restriction by any means – whether by diet or an operation.
”In patients who had started with Type 2 diabetes, fat levels in the pancreas (pancreatic triglyceride) decreased by 1.2% over the 8 weeks. Very exact methods were needed to be able to measure this and a new method using a special MRI scan was developed. With an average pancreas for a person with Type 2 diabetes having a volume of 50 ml, this is the equivalent of around 0.6 grams of fat.
According to the study by ETH Zurich and the International Diabetes Foundation, there are over 380 million diabetics around the world. Approximately, by the year 2030, over half a billion people will be suffering from type 2 diabetes.
Banana is the common name of a genus of tropical herbaceous plants. It can grow from 3 to 9 m and belongs to the family of the lily and the orchid.
In the study to reaffirm the traditional use of bananas for the treatment of diabetes in India, researchers at the University College of Medical Sciences, Dilshad Garden launched an investigation to assess the antidiabetic and antihyperlipidemic effects of the stem of the banana. In the experiment, diabetes was induced in rats by streptozotocin injection (45 mg/kg, i.p.). Diabetic rats were treated for 2 weeks with different doses of lyophilized stem juice of banana. (25, 50, and 100 mg/kg) to select the most effective dose.
* The most effective dose of lyophilized stem juice of M. sapientum Linn (Banana) was 50 mg/kg.
* The four weeks of treatment with this dose resulted in significant decreases in fasting and postprandial plasma glucose (FPG, PPG) levels.
* Serum insulin increased (P < 0.05) whereas HbA1c decreased (P < 0.05).
* Diabetes-induced changes to the lipid profile, muscle and liver glycogen, and enzyme activity (i.e. glucokinase, glucose-6-phosphatase, and HMG-CoA reductase) were restored near to normal levels by the application of banana.
These results suggested that the lyophilized stem juice of banana (M. sapientum Linn) exhibits antidiabetic and antihyperlipidemic effects.
Furthermore, in the study to find out the mechanism of the hypoglycemic effect of ethanol extract of banana pseudostem (EE) researchers suggested
* The ethanol extract from the banana significantly inhibited mammalian intestinal α-glucosidases and yeast α-glucosidase.
* Oral administration (100-200 mg kg(-1) body weight) of EE significantly suppressed the maltose/glucose-induced postprandial plasma glucose elevation and wielded an antihyperglycaemic effect in normal and alloxan-induced diabetic rats.
Dr. Ramu R, the lead scientist said, "EE might exert an anti-diabetic effect by inhibition of α-glucosidases from the intestine, in turn suppressing the carbohydrate absorption into the bloodstream. Hence the results extend a foundation for the future prospects of the food-derived enzyme inhibitors in the treatment of diabetes".
Additionally, according to the Central Food Technological Research Institute, banana flowers, and pseudostem have a low glycemic index and a high content of dietary fiber and antioxidants.
Application of the flower and pseudostem showed to inhibit diabetic symptoms like hyperglycemia, polyuria, polyphagia, polydipsia, urine sugar, and body weight in the rat model.
Taken together, unripe bananas may be used as a functional food for the prevention and combined with primary therapy for the treatment of diabetes in humans, depending on the confirmation of further data collection from the large example size and multi-center studies.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Antidiabetic and antihyperlipidemic effects of the stem of Musasapientum Linn. in streptozotocin-induced diabetic rats by Dikshit P1, Shukla K, Tyagi MK, Garg P, Gambhir JK, Shukla R.(PubMed)
(2) Investigation of antihyperglycaemic activity of banana (Musa sp. var. Nanjangud rasa bale) pseudostem in normal and diabetic rats by Ramu R1, Shirahatti PS, Zameer F, Nagendra Prasad MN. (PubMed).
(3) Beneficial effects of banana (Musa sp. var. elakki bale) flower and pseudostem on hyperglycemia and advanced glycation end-products (AGEs) in streptozotocin-induced diabetic rats by Bhaskar JJ1, Shobha MS, Sambaiah K, Salimath PV. (PubMed)
(4) The life and death of beta cells by ETH Zurich
(5) Type 2 diabetes reversed by losing fat from the pancreas by New Castle University
#Apricots Exert Anti #LiverCancer Activities by Inhibting #Cancer Cell Proliferation and Division, According to Studies
Kyle J. Norton
Apricot, a functional food may be the next pharmaceutical target for the finding of an effective medicine with potential in the treatment of liver cancer, some scientists suggested.
Liver cancer is a medical and chronic condition caused by irregular cell growth in the liver tissue.
What causes the mutation of liver cell DNA is unknown. However, according to epidemiological studies, cancer originating from the liver is associated with livers damaged by birth defects, alcohol abuse, or chronic infection with diseases such as hepatitis B and C, and hemochromatosis.
Non-alcoholic steatohepatitis (NASH), is the advanced form of non-alcoholic fatty liver disease (NAFLD). are one of the major risk factors associated with significant liver damage or the increased risk of liver cancer.
Unhealthy diet patterns and lifestyles also can contribute to the early onset of liver cancer. therefore making positive lifestyle choices such as Not smoking, eating a healthy diet, and keeping physically active are some of the ways that can reduce the risk of liver cancer.
The World Cancer Reserve Fund wrote," There is strong evidence that being overweight or obese is a cause of liver cancer, consuming approximately three or more alcoholic drinks a day is a cause of liver cancer, and consuming foods contaminated by aflatoxins (toxins produced by certain fungi) is a cause of liver cancer".
Men are about 3 times more likely than women to be diagnosed with the disease
According to the statistic, in the US., an estimated 30,610 men and 11,610 women will be diagnosed with primary liver cancer, causing the deaths of 20,540 men and 9,660 women.
The apricot tree is about 8–12 m tall and has a trunk up to 40 cm in diameter belonging to the family Rosaceae.
Apricot is classified in the family of plum with yellow to orange, often tinged red on the side which is exposed to the sun.
Chemical constituents of apricot include
Oleic acid, linoleic acid, palmitic.acid, glycolipids, phospholipids, benzoic acid (I), isorhamnetin (II), quercetin (III), kaempferol-3-O-beta-D-galactopyranoside (IV), isorhamnetin-3-O-beta-D-glucopyranoside (V), isoquercitrin (VI), hypericin (VII) and rutin (VIII)(a) and flavonoid glycosides.
In the assessment of MK615, an anti-cancer substance extracted from the Japanese apricot, researchers at the Dokkyo University School of Medicine conducted an investigation to examine the anti-neoplastic effect of MK615 against hepatocellular carcinoma (HCC).
Observation of the assays from 2 HCC lines, HuH7 and Hep3B, were cultured with MK615 at concentrations of 600, 300, 150, and 0 microg/mL found that
* MK615 inhibited the growth of, and lysed, HuH7 and Hep3B cells in a dose-dependent manner
* MK615 decreased the population of cells in the G2/M phase, according to the Cell cycle analysis.
* MK615 suppressed the expression of the function of Aurora A. associated with cancer cell proliferation by 34.3%, 32.9%, and 54.3% at 150, 300, and 600 microg/mL MK615, respectively.
Dr. after taking into account co and confounders said, "(These results suggested that) MK615 has an anti-cancer effect against HCC lines in vitro, and the effect is exerted through inhibition of Aurora-A activity".
Furthermore, in the evaluation of the clinical effects and feasibility of administering MK615 for patients with HCC recurred in the liver 8 mo after the surgery in a 60-year-old female with advanced HCC, researchers found that
* Radiofrequency ablation and transarterial infusion chemotherapy were performed but the recurrence was not controlled and one year after the intrahepatic recurrence, pulmonary and lymph metastasis reappeared.
* Administration of chemo drug Sorafenib was not effective.
* MK615 was administered as a final alternative therapy after informed consent was obtained from the patient.
3 months of MK615 injection exerted a significant effect in decreasing her alpha-fetoprotein level and sizes of both the lymph node and pulmonary metastases. The patient has survived for more than 17 mo after the MK615 administration.
These results suggested that MK615 is effective against advanced liver cancer metastases.
Taken together, apricot may be considered a functional food for the prevention and adjunct therapy for the treatment of liver cancer.
However, further data collection large example size and multi-center studies performed with human consumption of the whole food apricot during the course of the disease will be necessary to complete the picture of apricot anti-liver cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
Apricot, a functional food may be the next pharmaceutical target for the finding of an effective medicine with potential in the treatment of liver cancer, some scientists suggested.
Liver cancer is a medical and chronic condition caused by irregular cell growth in the liver tissue.
What causes the mutation of liver cell DNA is unknown. However, according to epidemiological studies, cancer originating from the liver is associated with livers damaged by birth defects, alcohol abuse, or chronic infection with diseases such as hepatitis B and C, and hemochromatosis.
Non-alcoholic steatohepatitis (NASH), is the advanced form of non-alcoholic fatty liver disease (NAFLD). are one of the major risk factors associated with significant liver damage or the increased risk of liver cancer.
Unhealthy diet patterns and lifestyles also can contribute to the early onset of liver cancer. therefore making positive lifestyle choices such as Not smoking, eating a healthy diet, and keeping physically active are some of the ways that can reduce the risk of liver cancer.
The World Cancer Reserve Fund wrote," There is strong evidence that being overweight or obese is a cause of liver cancer, consuming approximately three or more alcoholic drinks a day is a cause of liver cancer, and consuming foods contaminated by aflatoxins (toxins produced by certain fungi) is a cause of liver cancer".
Men are about 3 times more likely than women to be diagnosed with the disease
According to the statistic, in the US., an estimated 30,610 men and 11,610 women will be diagnosed with primary liver cancer, causing the deaths of 20,540 men and 9,660 women.
The apricot tree is about 8–12 m tall and has a trunk up to 40 cm in diameter belonging to the family Rosaceae.
Apricot is classified in the family of plum with yellow to orange, often tinged red on the side which is exposed to the sun.
Chemical constituents of apricot include
Oleic acid, linoleic acid, palmitic.acid, glycolipids, phospholipids, benzoic acid (I), isorhamnetin (II), quercetin (III), kaempferol-3-O-beta-D-galactopyranoside (IV), isorhamnetin-3-O-beta-D-glucopyranoside (V), isoquercitrin (VI), hypericin (VII) and rutin (VIII)(a) and flavonoid glycosides.
In the assessment of MK615, an anti-cancer substance extracted from the Japanese apricot, researchers at the Dokkyo University School of Medicine conducted an investigation to examine the anti-neoplastic effect of MK615 against hepatocellular carcinoma (HCC).
Observation of the assays from 2 HCC lines, HuH7 and Hep3B, were cultured with MK615 at concentrations of 600, 300, 150, and 0 microg/mL found that
* MK615 inhibited the growth of, and lysed, HuH7 and Hep3B cells in a dose-dependent manner
* MK615 decreased the population of cells in the G2/M phase, according to the Cell cycle analysis.
* MK615 suppressed the expression of the function of Aurora A. associated with cancer cell proliferation by 34.3%, 32.9%, and 54.3% at 150, 300, and 600 microg/mL MK615, respectively.
Dr. after taking into account co and confounders said, "(These results suggested that) MK615 has an anti-cancer effect against HCC lines in vitro, and the effect is exerted through inhibition of Aurora-A activity".
Furthermore, in the evaluation of the clinical effects and feasibility of administering MK615 for patients with HCC recurred in the liver 8 mo after the surgery in a 60-year-old female with advanced HCC, researchers found that
* Radiofrequency ablation and transarterial infusion chemotherapy were performed but the recurrence was not controlled and one year after the intrahepatic recurrence, pulmonary and lymph metastasis reappeared.
* Administration of chemo drug Sorafenib was not effective.
* MK615 was administered as a final alternative therapy after informed consent was obtained from the patient.
3 months of MK615 injection exerted a significant effect in decreasing her alpha-fetoprotein level and sizes of both the lymph node and pulmonary metastases. The patient has survived for more than 17 mo after the MK615 administration.
These results suggested that MK615 is effective against advanced liver cancer metastases.
Taken together, apricot may be considered a functional food for the prevention and adjunct therapy for the treatment of liver cancer.
However, further data collection large example size and multi-center studies performed with human consumption of the whole food apricot during the course of the disease will be necessary to complete the picture of apricot anti-liver cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A novel anti-cancer substance, MK615, from ume, a variety of Japanese apricot, inhibits the growth of hepatocellular carcinoma cells by suppressing Aurora A kinase activity by Okada T1, Sawada T, Osawa T, Adachi M, Kubota K.(PubMed)
(2) Advanced hepatocellular carcinoma responds to MK615, a compound extract from the Japanese apricot "Prunus mume" by Hoshino T1, Takagi H, Naganuma A, Koitabashi E, Uehara S, Sakamoto N, Kudo T, Sato K, Kakizaki S.(PubMed)
(2) Advanced hepatocellular carcinoma responds to MK615, a compound extract from the Japanese apricot "Prunus mume" by Hoshino T1, Takagi H, Naganuma A, Koitabashi E, Uehara S, Sakamoto N, Kudo T, Sato K, Kakizaki S.(PubMed)
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