Kyle J. Norton
Atherosclerosis is a chronic disease associated with hardening and stiffing of the arterial wall caused by long-term plague accumulation, leading to the reduced function of the arterial to transport oxygen risk blood to the heart and the body.
Atherosclerosis is also a leading cause of 3 types of cardiovascular disease, including heart attacks, strokes, and peripheral vascular disease.
Plaque is a substance made up of fat, cholesterol, calcium, and other substances found in the blood.
Atherosclerosis is a very slow-growing disease, the progression of the disease is associated with slow plaque accumulation which starts at an early age, depending on the diet and lifestyle pattern.
The most common symptoms of atherosclerosis are associated with the reduced supply of oxygen to tissue and organs, including chest pain or angina. pain in your leg, arm, shortness of breath. fatigue. confusion, muscle weakness in your legs from lack of circulation.
If you experience some of the above symptoms, please make sure that you check with your doctor to rule the possibility of atherosclerosis.
Conventionally, most cases of atherosclerosis are treated with Angiotensin-converting enzyme (ACE) inhibitors which help to slow the progression of atherosclerosis by lowering blood pressure and producing other beneficial effects on the heart arteries.
However, some researchers suggested that heart-healthy lifestyle changes may also have a strong implication on the disease.
Dr. Matthias Nahrendorf, the lead scientist in the examination of the link between lifestyle and risk of atherosclerosis, said, "Accumulating data indicate that psychosocial stress and a high-fat, high-cholesterol diet aggravate the cardiovascular disease, whereas regular physical activity and healthy sleeping habits help prevent it".
The results clearly suggested that people followed a healthy lifestyle are associated with the risk of
atherosclerosis.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
On review of the clinical and pharmacological of artichoke (Cynara scolymus L.), used in European medicine from the 18th century for the treatment of chronic disease, researchers examined the herbal remedy effect against atherosclerosis.
Injection of artichoke inhibited the onset and progression of atherosclerosis by modulating the levels of plasma lipid levels through the inhibition of lipid peroxidation.
Futhermore, artichoke also induced the production of antioxidant enzymes against the free radical oxidation in the liver tissues.
In other words, artichoke protected the arteries against the accumulation of plaque on the arterial wall by protecting the liver in lipid metabolism through its antioxidant activity.
Furthermore, in order to reveal more information about artichoke anti-atherosclerosis activity, researchers evaluated the polyphenols and flavonoids in artichoke leaf tincture (ALT) against cellular oxidative damage.
The study included 18 male Wistar albino rats divided into three groups (n = 6/group):
* The control group (CG) was fed with standard pellet chow for 11 weeks;
* The AD group was fed for a similar period of time with pellet chow supplemented with 2% cholesterol, 3% sunflower oil and 1% sodium cholate. and
* The ADA group was fed with pellet chow (for 1 week), the atherogenic diet (see above) for the following 4 weeks and then with ALT (0.1 mL/kg body weight) and atherogenic diet for 6 weeks.
During the study, researchers found that compared to the AD group
* The ADA group exerted a significant increase in antioxidant activity observed by the expression of heme oxygenase-1 (HO1).
* The ADA group lower the expression of MCP-1 which has been strongly linked to atherosclerosis in both animal and human studies.
* The ADA group lowers the DNA scores associated with the risk of atherosclerosis.
Compared to the CG group, the HO-1 mRNA-involved immune response was also lower in the ADA group.
In other words, artichoke inhibited the effects of the atherogenic diet through reduced MCP-1 expression, thereby preventing oxidative damage.
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of atherosclerosis, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) [Artichoke--the untapped potential of herbal medicine in the treatment of atherosclerosis and liver diseases].[Article in Polish] by Horoszkiewicz M1, Kulza M, Malinowska K, Woźniak A, Seńczuk-Przybyłowska M, Wachowiak A, Florek E.(PubMed)
(2) The role of artichoke leaf tincture (Cynara scolymus) in the suppression of DNA damage and atherosclerosis in rats fed an atherogenic diet by Bogavac-Stanojevic N1, Kotur Stevuljevic J1, Cerne D2, Zupan J2, Marc J2, Vujic Z3, Crevar-Sakac M3, Sopic M1, Munjas J1, Radenkovic M4, Jelic-Ivanovic Z. (PubMed)
(3) Lifestyle Effects on Hematopoiesis and Atherosclerosis by Matthias Nahrendorf and Filip K. Swirski. (Circulation Research)
Tuesday, 27 June 2023
#Bromelain Speeds Up #WoundHealing Through Its its Angiogenic Activity, Researchers Say
Kyle J. Norton
Skin healing is a natural process to reconstruct the skin back to its originated stage after skin damage.
Skin is a large organ in the human body which only protects our body against foreign invaders but also serves as a third detoxed system after the liver and kidney.
Skin healing is depending on the size of the wound, a small size can be healed quickly without using any medication. However, the large size wound in most cases is required stitches.
Similar to wound healing, at the acute phase of infection, the macrophages of the immune first line of defense stimulate the blood clot to cover the wound or cut and production of proinflammatory cytokines to destroy foreign invaders.
In this phase, patients may experience symptoms of skin redness, tenderness, and swelling around the wound or cut.
Depending on the size of a skin wound, the next overlap stage is broken blood vessels in the wound is repaired and new tissue is grown followed by the creation of collagen, the fibers that form the foundation for new tissue.
This process continues until the skin is stronger or back to its original form.
In the acute phase of infection, overproduction of pro-inflammatory cytokines induced by immune response may cause damage to healthy cells, leading to scar forming.
Additionally, any interruption of these processes may induce the formation of scars.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a potential compound for speeding up wound healing, researchers compared the structural integrity of bromelain (debridement enzyme) in the healing process.
The study included a combinational multiphasic delivery system that delivers biomolecules of bromelain through the fabrication of coaxial electrospinning of different biocompatible polymers.
In vitro, the fabricated scaffold delivery system sustained the release of debriding protease and its bioactive components in a timely fashion showing a significant effect on wound healing.
Furthermore, the fabricated scaffold used in debridement enzyme also promoted the wound healing process by its angiogenic potential through in vitro migration of endothelial cells and increased new capillaries from the existing blood vessel in response to wound healing.
Moreover, in vivo, studies also confirm the efficacy of the fabricated scaffold used in the delivery of bromelain.
Based on the findings, researchers said, "Our results, therefore, open up a new avenue for designing a bioactive combinational multiphasic delivery system to enhance wound healing".
In order to assess the role and clinical advantages of enzymatic debridement by a mixture of proteolytic enzymes enriched in Bromelain (Nexobrid®) on wound healing, researchers examined the mutual experience of applying enzymatic debridement in more than 500 adult and pediatric patients by the consensus panelists.
The statement included the answer to questions related to pain management and anesthesia, the timing of application, technique of application, after-intervention care, skin grafting after enzymatic debridement, blood loss, training strategies, learning curve, and areas of future research needs.
According to the statements returned by the participant, in 68 consensus statements, enzymatic debridement used showed a higher degree of consensus with a unanimous consensus in 88.2% of statements, and the lowest degree of consensus of 70% in only 3 statements.
Taken altogether, bromelain used alone or combined with the multiphasic delivery system may be considered supplements for speedup wound healing, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Eschar removal by bromelain-based enzymatic debridement (Nexobrid®) in burns: An European consensus by Hirche C1, Citterio A2, Hoeksema H3, Koller J4, Lehner M5, Martinez JR6, Monstrey S3, Murray A7, Plock JA8, Sander F9, Schulz A10, Ziegler B11, Kneser U. (PubMed)
(2) Fabrication of core-shell nanofibers for controlled delivery of bromelain and salvianolic acid B for skin regeneration in wound therapeutics by Shoba E1, Lakra R, Syamala Kiran M, Korrapati PS. (PubMed)
Skin healing is a natural process to reconstruct the skin back to its originated stage after skin damage.
Skin is a large organ in the human body which only protects our body against foreign invaders but also serves as a third detoxed system after the liver and kidney.
Skin healing is depending on the size of the wound, a small size can be healed quickly without using any medication. However, the large size wound in most cases is required stitches.
Similar to wound healing, at the acute phase of infection, the macrophages of the immune first line of defense stimulate the blood clot to cover the wound or cut and production of proinflammatory cytokines to destroy foreign invaders.
In this phase, patients may experience symptoms of skin redness, tenderness, and swelling around the wound or cut.
Depending on the size of a skin wound, the next overlap stage is broken blood vessels in the wound is repaired and new tissue is grown followed by the creation of collagen, the fibers that form the foundation for new tissue.
This process continues until the skin is stronger or back to its original form.
In the acute phase of infection, overproduction of pro-inflammatory cytokines induced by immune response may cause damage to healthy cells, leading to scar forming.
Additionally, any interruption of these processes may induce the formation of scars.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In finding a potential compound for speeding up wound healing, researchers compared the structural integrity of bromelain (debridement enzyme) in the healing process.
The study included a combinational multiphasic delivery system that delivers biomolecules of bromelain through the fabrication of coaxial electrospinning of different biocompatible polymers.
In vitro, the fabricated scaffold delivery system sustained the release of debriding protease and its bioactive components in a timely fashion showing a significant effect on wound healing.
Furthermore, the fabricated scaffold used in debridement enzyme also promoted the wound healing process by its angiogenic potential through in vitro migration of endothelial cells and increased new capillaries from the existing blood vessel in response to wound healing.
Moreover, in vivo, studies also confirm the efficacy of the fabricated scaffold used in the delivery of bromelain.
Based on the findings, researchers said, "Our results, therefore, open up a new avenue for designing a bioactive combinational multiphasic delivery system to enhance wound healing".
In order to assess the role and clinical advantages of enzymatic debridement by a mixture of proteolytic enzymes enriched in Bromelain (Nexobrid®) on wound healing, researchers examined the mutual experience of applying enzymatic debridement in more than 500 adult and pediatric patients by the consensus panelists.
The statement included the answer to questions related to pain management and anesthesia, the timing of application, technique of application, after-intervention care, skin grafting after enzymatic debridement, blood loss, training strategies, learning curve, and areas of future research needs.
According to the statements returned by the participant, in 68 consensus statements, enzymatic debridement used showed a higher degree of consensus with a unanimous consensus in 88.2% of statements, and the lowest degree of consensus of 70% in only 3 statements.
Taken altogether, bromelain used alone or combined with the multiphasic delivery system may be considered supplements for speedup wound healing, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Eschar removal by bromelain-based enzymatic debridement (Nexobrid®) in burns: An European consensus by Hirche C1, Citterio A2, Hoeksema H3, Koller J4, Lehner M5, Martinez JR6, Monstrey S3, Murray A7, Plock JA8, Sander F9, Schulz A10, Ziegler B11, Kneser U. (PubMed)
(2) Fabrication of core-shell nanofibers for controlled delivery of bromelain and salvianolic acid B for skin regeneration in wound therapeutics by Shoba E1, Lakra R, Syamala Kiran M, Korrapati PS. (PubMed)
#GingerPowder, Relieves Pain and Inflammation in Patients with Knee #Osteoarthritis, According to Studies
Kyle J. Norton
Ginger may have a potential and positive effect in ameliorating the symptoms of pain and complication of reduced quality of life in patients with osteoarthritis, some scientists suggested.
Osteoarthritis (OA) is a chronic condition of a type of joint disease characterized by the breaking down of joint cartilage and underlying bone due to “wear and tear” of joints over time.
Some researchers suggested that OA is a degenerative disease characterized by “low-grade inflammation” in cartilage and synovium, affecting the joint structure and progressive deterioration of cartilage.
According to the statistic from the NIH, osteoarthritis (OA) is the most common joint disorder in the US. Among adults, 60 years of age or older the prevalence of symptomatic knee and sadly OA affects approximately 10% of men and 13% of women.
Epidemiological strongly suggested that obese and overweight which have a strong impact on weight-bearing joints, the genetic preposition of a patient can make such a patient more susceptible to the disease compared to others who do not, people with joint injuries that did heal properly at a younger age and people with occupations that require standing for long periods of time, repetitive bending, heavy lifting or other movements and the increase in age are associated to the increased risk of the onset of the disease.
The most common symptoms of osteoarthritis are joint pain and stiffness.
Dr. Giuseppe Musumeci, the lead author in the study "Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression" suggested that besides the risk factors mentioned above, dietary factors also play an important role for the onset of the disease.
In the dietary aspect in the induction of OA, the research team wrote, "This diet (The Western diet) is mainly constituted by preservative and harmful substances, such as animal fat and glucose excessive concentration and lack of nutritional factors, such as vitamins and nutrient minerals essential for our body. Moreover, bad dietary habits may predispose people to obesity, which is responsible for both metabolic destroying processes affecting the cartilage and overload of the joints, especially hips, and knees".
And, " quantity and quality of nutrient intake. Low intake of vitamin D and vitamin C is a possible risk factor for knee OA, while certain food groups, such as milk and dairy products, meat and poultry are beneficial for knee OA. Thus we could affirm that nutritional imbalance, combined with endocrine abnormalities, may be involved in the pathogenesis of OA".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to reaffirm the traditional use of ginger for the treatment of osteoarthritis, a joint review led by the Copenhagen University Hospital, Bispebjerg, and Frederiksberg was conducted to assess the clinical efficacy and safety of oral ginger for the symptomatic treatment of osteoarthritis (OA).
The study was carried out by searching the randomized controlled trials (RCTs) comparing oral ginger treatment with placebo in OA patients aged >18 years satisfied the predetermined guidelines and criteria, including the outcomes of the reduction in pain and disability.
Out of 122 retrieved references, 117 were discarded, and only 5 five trials (593 patients) were selected for meta-analyses.
All 5 remained studies suggested that ginger intake scored a statistically significant pain reduction.
Furthermore, the application of ginger in subjects with osteoarthritis demonstrates a statistically significant reduction in disability compared to the control.
However, according to the returned questionnaires from the participants, researchers surprisingly found that patients given ginger are more than twice as likely to discontinue treatment compared to placebo.
Dr. Mozaffari-Khosravi H, the lead author, launched a joint study to determine the ginger powder effects in relieving pain and inflammation in patients with osteoarthritis.
120 participants selected for the randomized double-blind placebo-controlled 3-month clinical trial for knee osteoarthritis were randomly assigned to one of two groups: the ginger group (GG) or the placebo group (PG).
Ginger selected group was given capsules containing 500 mg of ginger powder, while the PG group was given capsules filled with 500 mg starch.
At the baseline, proinflammatory cytokine concentrations did not differ by group, observed by the participant's blood sample.
After 3 months, GG showed a significant reduction of cytokines compared to the PG.
In the final report, the research team wrote, "Ginger supplementation may have promising benefits for knee osteoarthritis".
These results reconfirming the use of ginger for the treatment of osteoarthritis in traditional medicine with no side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials by Bartels EM1, Folmer VN2, Bliddal H2, Altman RD3, Juhl C4, Tarp S2, Zhang W5, Christensen R. (PubMed)
(2) Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial by Mozaffari-Khosravi H1,2, Naderi Z1, Dehghan A3, Nadjarzadeh A1, Fallah Huseini H. (PubMed)
(3) Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression by Giuseppe Musumeci,1,* Flavia Concetta Aiello,1 Marta Anna Szychlinska,1Michelino Di Rosa,2 Paola Castrogiovanni,1 and Ali Mobasheri. (PubMed)
Ginger may have a potential and positive effect in ameliorating the symptoms of pain and complication of reduced quality of life in patients with osteoarthritis, some scientists suggested.
Osteoarthritis (OA) is a chronic condition of a type of joint disease characterized by the breaking down of joint cartilage and underlying bone due to “wear and tear” of joints over time.
Some researchers suggested that OA is a degenerative disease characterized by “low-grade inflammation” in cartilage and synovium, affecting the joint structure and progressive deterioration of cartilage.
According to the statistic from the NIH, osteoarthritis (OA) is the most common joint disorder in the US. Among adults, 60 years of age or older the prevalence of symptomatic knee and sadly OA affects approximately 10% of men and 13% of women.
Epidemiological strongly suggested that obese and overweight which have a strong impact on weight-bearing joints, the genetic preposition of a patient can make such a patient more susceptible to the disease compared to others who do not, people with joint injuries that did heal properly at a younger age and people with occupations that require standing for long periods of time, repetitive bending, heavy lifting or other movements and the increase in age are associated to the increased risk of the onset of the disease.
The most common symptoms of osteoarthritis are joint pain and stiffness.
Dr. Giuseppe Musumeci, the lead author in the study "Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression" suggested that besides the risk factors mentioned above, dietary factors also play an important role for the onset of the disease.
In the dietary aspect in the induction of OA, the research team wrote, "This diet (The Western diet) is mainly constituted by preservative and harmful substances, such as animal fat and glucose excessive concentration and lack of nutritional factors, such as vitamins and nutrient minerals essential for our body. Moreover, bad dietary habits may predispose people to obesity, which is responsible for both metabolic destroying processes affecting the cartilage and overload of the joints, especially hips, and knees".
And, " quantity and quality of nutrient intake. Low intake of vitamin D and vitamin C is a possible risk factor for knee OA, while certain food groups, such as milk and dairy products, meat and poultry are beneficial for knee OA. Thus we could affirm that nutritional imbalance, combined with endocrine abnormalities, may be involved in the pathogenesis of OA".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to reaffirm the traditional use of ginger for the treatment of osteoarthritis, a joint review led by the Copenhagen University Hospital, Bispebjerg, and Frederiksberg was conducted to assess the clinical efficacy and safety of oral ginger for the symptomatic treatment of osteoarthritis (OA).
The study was carried out by searching the randomized controlled trials (RCTs) comparing oral ginger treatment with placebo in OA patients aged >18 years satisfied the predetermined guidelines and criteria, including the outcomes of the reduction in pain and disability.
Out of 122 retrieved references, 117 were discarded, and only 5 five trials (593 patients) were selected for meta-analyses.
All 5 remained studies suggested that ginger intake scored a statistically significant pain reduction.
Furthermore, the application of ginger in subjects with osteoarthritis demonstrates a statistically significant reduction in disability compared to the control.
However, according to the returned questionnaires from the participants, researchers surprisingly found that patients given ginger are more than twice as likely to discontinue treatment compared to placebo.
Dr. Mozaffari-Khosravi H, the lead author, launched a joint study to determine the ginger powder effects in relieving pain and inflammation in patients with osteoarthritis.
120 participants selected for the randomized double-blind placebo-controlled 3-month clinical trial for knee osteoarthritis were randomly assigned to one of two groups: the ginger group (GG) or the placebo group (PG).
Ginger selected group was given capsules containing 500 mg of ginger powder, while the PG group was given capsules filled with 500 mg starch.
At the baseline, proinflammatory cytokine concentrations did not differ by group, observed by the participant's blood sample.
After 3 months, GG showed a significant reduction of cytokines compared to the PG.
In the final report, the research team wrote, "Ginger supplementation may have promising benefits for knee osteoarthritis".
These results reconfirming the use of ginger for the treatment of osteoarthritis in traditional medicine with no side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials by Bartels EM1, Folmer VN2, Bliddal H2, Altman RD3, Juhl C4, Tarp S2, Zhang W5, Christensen R. (PubMed)
(2) Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial by Mozaffari-Khosravi H1,2, Naderi Z1, Dehghan A3, Nadjarzadeh A1, Fallah Huseini H. (PubMed)
(3) Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression by Giuseppe Musumeci,1,* Flavia Concetta Aiello,1 Marta Anna Szychlinska,1Michelino Di Rosa,2 Paola Castrogiovanni,1 and Ali Mobasheri. (PubMed)
#Lycopene Found in #Tomatoes Protects the Lungs Against Pulmonary Oxidative Stress By Inhibiting the ProinflammatoryCytokines
Kyle J. Norton
Pulmonary oxidative stress is a condition of oxidative stress in the lung.
The lung is a breathing organ containing a pair of spongy, air-filled organs located on either side of the chest (thorax) by taking oxygen to the blood vessels and then passing them to all parts of our body.
Furthermore, the lung also exhales the waste product called carbon dioxide, through breathing.
Oxidative stress is a result of an imbalance of the levels of free radicals compared to the antioxidant enzymes in the body.
Oxidative stress is either expressed by overexpression of free radicals or reduced levels of antioxidants or both.
Free radicals can be everywhere in the environment such as the air we breathe, and the foods we eat. they can also be produced by cell metabolism in the body.
Believe it or not, free radicals in moderate amounts are necessary for our body to function, including NO for muscle relaxation.
Epidemiologically, oxidative stress has been found to induce lipid and protein oxidation and cell DNA damage.
According to the free radical theory, aging posits caused by the accumulation of damage inflicted by reactive oxygen species (ROS) associated with various chronic diseases such as atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke.
In the lung, oxidative stress also was shown to elevate the risk of the pathogenesis of chronic obstructive pulmonary disease.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
With an aim to find a natural and potential whole food for the treatment of diseases associated with pulmonary oxidative stress, researchers investigated dietary supplementation with a known source of antioxidants (tomato juice, TJ) in the protection of the lung from injury caused by breathing hyperoxic gas.
The study included the examination of the results from the selected neonatal mice (C57BL6/J) who breathed either 65% O2 (hyperoxia) or room air from birth until postnatal day 7 (P7d).
At P56d, TJ protects the lung cell integrity and viability by increasing the levels of total antioxidant capacity (TAC), decreasing oxidative stress, and reversing the hyperoxia-induced increase in bronchiolar smooth muscle.
Furthermore, injection of TJ alone also decreased the protein involved in the production of pro-inflammatory cytokines.
In hyperoxia, TJ increased TNF-α expression and did not alter the hyperoxia-induced increase in leukocyte number.
In other words, TJ protects the lung against oxidative stress by inhibiting and exhibiting certain proteins associated with proinflammation without increasing the production of immune white blood cells via its pulmonary antioxidants.
Based on these results, Dr. Bouch S, the lead scientist said, "TJ supplementation during and after neonatal exposure to hyperoxia protects the lung from some but not all aspects of hyperoxia-induced injury".
In other to reveal additional information about tomato anti-pulmonary oxidative stress effect, researchers examined the bioactive compound lycopene extracted from tomatoes in pulmonary fibrosis (PF) in an animal model.
The study included 60 Sprague-Dawley rats induced pulmonary fibrosis (PF) by BLM randomly divided into 3 groups of 20 rats each for a normal control group (group C), BLM-treated group (group M), and lycopene + BLM-treated group (group L).
Additionally, the rats in groups M and L were subjected to intratracheal instillation of BLM to induce PF; group C served as a sham control (intratracheal instillation of normal saline). Lycopene diluted with olive oil was administered at a dose of 5 mg/kg body weight once a day in group L after BLM instillation, and groups C and M were treated with the same amounts of olive oil.
The lung coefficients in group L treated with lycopene were reduced (day 14, P < .01) as well as the extent of alveolitis (day 7 and 14, P < .05) and PF (day 14 and 28, P < .05) compared with group M.
Lycopene treated group also showed significantly reduced levels of proteins associated with the immune system response against the acute phase of infection.
Furthermore, lycopene levels of oxidative stress markers in the lung were observed by the decreased levels of malondialdehyde plasma.
In other words, lycopene protected the lung of the tested rat by reducing oxidative stress via the stimulation of the production of antioxidant enzymes.
Taken altogether, tomatoes processed with a high amount of bioactive compound lycopene may be considered supplements for the prevention and treatment of diseases associated with pulmonary oxidative stress, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Impact of Dietary Tomato Juice on Changes in Pulmonary Oxidative Stress, Inflammation, and Structure Induced by Neonatal Hyperoxia in Mice (Mus musculus) by Bouch S1, Harding R1, O'Reilly M1, Wood LG2, Sozo F. (PubMed)
(2) Lycopene from tomatoes partially alleviates the bleomycin-induced experimental pulmonary fibrosis in rats by Zhou C1, Han W, Zhang P, Cai M, Wei D, Zhang C. (PubMed)
Pulmonary oxidative stress is a condition of oxidative stress in the lung.
The lung is a breathing organ containing a pair of spongy, air-filled organs located on either side of the chest (thorax) by taking oxygen to the blood vessels and then passing them to all parts of our body.
Furthermore, the lung also exhales the waste product called carbon dioxide, through breathing.
Oxidative stress is a result of an imbalance of the levels of free radicals compared to the antioxidant enzymes in the body.
Oxidative stress is either expressed by overexpression of free radicals or reduced levels of antioxidants or both.
Free radicals can be everywhere in the environment such as the air we breathe, and the foods we eat. they can also be produced by cell metabolism in the body.
Believe it or not, free radicals in moderate amounts are necessary for our body to function, including NO for muscle relaxation.
Epidemiologically, oxidative stress has been found to induce lipid and protein oxidation and cell DNA damage.
According to the free radical theory, aging posits caused by the accumulation of damage inflicted by reactive oxygen species (ROS) associated with various chronic diseases such as atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke.
In the lung, oxidative stress also was shown to elevate the risk of the pathogenesis of chronic obstructive pulmonary disease.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
With an aim to find a natural and potential whole food for the treatment of diseases associated with pulmonary oxidative stress, researchers investigated dietary supplementation with a known source of antioxidants (tomato juice, TJ) in the protection of the lung from injury caused by breathing hyperoxic gas.
The study included the examination of the results from the selected neonatal mice (C57BL6/J) who breathed either 65% O2 (hyperoxia) or room air from birth until postnatal day 7 (P7d).
At P56d, TJ protects the lung cell integrity and viability by increasing the levels of total antioxidant capacity (TAC), decreasing oxidative stress, and reversing the hyperoxia-induced increase in bronchiolar smooth muscle.
Furthermore, injection of TJ alone also decreased the protein involved in the production of pro-inflammatory cytokines.
In hyperoxia, TJ increased TNF-α expression and did not alter the hyperoxia-induced increase in leukocyte number.
In other words, TJ protects the lung against oxidative stress by inhibiting and exhibiting certain proteins associated with proinflammation without increasing the production of immune white blood cells via its pulmonary antioxidants.
Based on these results, Dr. Bouch S, the lead scientist said, "TJ supplementation during and after neonatal exposure to hyperoxia protects the lung from some but not all aspects of hyperoxia-induced injury".
In other to reveal additional information about tomato anti-pulmonary oxidative stress effect, researchers examined the bioactive compound lycopene extracted from tomatoes in pulmonary fibrosis (PF) in an animal model.
The study included 60 Sprague-Dawley rats induced pulmonary fibrosis (PF) by BLM randomly divided into 3 groups of 20 rats each for a normal control group (group C), BLM-treated group (group M), and lycopene + BLM-treated group (group L).
Additionally, the rats in groups M and L were subjected to intratracheal instillation of BLM to induce PF; group C served as a sham control (intratracheal instillation of normal saline). Lycopene diluted with olive oil was administered at a dose of 5 mg/kg body weight once a day in group L after BLM instillation, and groups C and M were treated with the same amounts of olive oil.
The lung coefficients in group L treated with lycopene were reduced (day 14, P < .01) as well as the extent of alveolitis (day 7 and 14, P < .05) and PF (day 14 and 28, P < .05) compared with group M.
Lycopene treated group also showed significantly reduced levels of proteins associated with the immune system response against the acute phase of infection.
Furthermore, lycopene levels of oxidative stress markers in the lung were observed by the decreased levels of malondialdehyde plasma.
In other words, lycopene protected the lung of the tested rat by reducing oxidative stress via the stimulation of the production of antioxidant enzymes.
Taken altogether, tomatoes processed with a high amount of bioactive compound lycopene may be considered supplements for the prevention and treatment of diseases associated with pulmonary oxidative stress, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Impact of Dietary Tomato Juice on Changes in Pulmonary Oxidative Stress, Inflammation, and Structure Induced by Neonatal Hyperoxia in Mice (Mus musculus) by Bouch S1, Harding R1, O'Reilly M1, Wood LG2, Sozo F. (PubMed)
(2) Lycopene from tomatoes partially alleviates the bleomycin-induced experimental pulmonary fibrosis in rats by Zhou C1, Han W, Zhang P, Cai M, Wei D, Zhang C. (PubMed)
#Bisdemethoxycurcumin (BDMC) Found in #Turmeric Protects the Liver Cells Against #LiverDiseases Associated with Hepatic Fatty Accumulation
Kyle J. Norton
Hepatoprotection is the action including the use of a substance such as an herbal remedy to protect the liver against damage and injury.
Antihepatotoxicity is the ability that protects the liver against toxins.
Acute liver diseases in most cases are caused by drugs and long-term intake of certain medications. Most acute liver diseases can be cured if the cause is found.
Chronic liver diseases (CLD) are any liver diseases that last more than 6 months. Most chronic liver diseases are caused by a genetic preposition or a variety of factors that damage the liver, including viruses and alcohol use.
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the world affecting 25% of the general population most of them in the Western world.
Some researchers suggested that the use of substances to protect the liver may involve several mechanisms, including strengthening the liver, gastrointestinal and immune systems.
Dr. C. Girish, the lead scientist in the discussion of the hepatoprotective effect, wrote, " The regulation of the gastrointestinal system may improve the general well-being of the patients, as well as improvement of constipation, may prevent the absorption of harmful substances and indirectly decrease ascites (Langmead and Rampton, 2001). The protection of liver cells against toxic materials including drugs, lipid peroxidation, and free radical injury may decrease inflammation, improve liver blood flow, and ultimately help in the reduction of ascites and blood pressure (Yang et al., 2000)".
In other words, herbal medicine expressed liver protection not only by improving the blood flow to the liver but also through regulating the gastrointestinal system against the building up toxins in the induction of free radicals and suppressing the normal function of the liver, and improving the immune system against inflammation induced the lipid oxidation.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, and wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential ingredient for the protection of liver integrity, researchers examined curcumin, the active ingredient of turmeric's therapeutic potential for the treatment of liver disorders.
The application of curcumin showed liver protective activity by inhibiting the liver toxicity caused by long-term excessive alcohol drinking and acetaminophen, lindane, carbon tetrachloride (CCL4), and diethylnitrosamine.
Furthermore, curcumin also restored liver functioning in heavy metals-induced hepatotoxicities models.
In the nonalcoholic fatty liver disease (NAFLD), the most common cause of the chronic liver disease model, researchers examined the Bisdemethoxycurcumin (BDMC), a polyphenolic compound derived from the Curcumae Longae Rhizoma liver protective activity.
The study included C57BL/6J mice divided into five groups of normal (normal diet without any treatment), methionine choline-deficient (MCD)-diet (MCD diet only), MCD + silymarin (SIL) 100 mg/kg group, MCD + BDMC 100 mg/kg group, MCD + SIL 50 mg/kg + BDMC 50 mg/kg group.
BDMC protected the liver against fatty change compared to severe hepatic fatty accumulation in the MCD-diet group.
BDMC increased liver function significantly, compared to that of the loss of liver function in the MCD-diet group.
Most importantly, BDMC showed an inhibitory effect on liver lipogenesis by reducing associated gene expression caused by the MCD diet.
Moreover, combinations of BDMC with SIL had a synergistic effect against MCD-diet models.
Based on the findings, Dr. Kim SB, the lead scientist said, "Our findings indicate that BDMC has a potential suppressive effect on NAFLD. Therefore, our data suggest that BDMC may act as a novel and potent therapeutic agent against NAFLD".
Taken altogether, turmeric and its bioactive compound curcumin may be considered a remedy for the improvement of liver function, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects by Khan H1, Ullah H2, Nabavi SM. (PubMed)
(2) Hepatoprotective Effect and Synergism of Bisdemethoxycurcumin against MCD Diet-Induced Nonalcoholic Fatty Liver Disease in Mice.
Kim SB1, Kang OH1, Lee YS2, Han SH3, Ahn YS3, Cha SW3, Seo YS1, Kong R2, Kwon DY. (PubMed)
(3) Herbal Drugs on the Liver by C. Girish, S.C. Pradhan, in Liver Pathophysiology, 2017, (Science Direct)
Hepatoprotection is the action including the use of a substance such as an herbal remedy to protect the liver against damage and injury.
Antihepatotoxicity is the ability that protects the liver against toxins.
Acute liver diseases in most cases are caused by drugs and long-term intake of certain medications. Most acute liver diseases can be cured if the cause is found.
Chronic liver diseases (CLD) are any liver diseases that last more than 6 months. Most chronic liver diseases are caused by a genetic preposition or a variety of factors that damage the liver, including viruses and alcohol use.
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the world affecting 25% of the general population most of them in the Western world.
Some researchers suggested that the use of substances to protect the liver may involve several mechanisms, including strengthening the liver, gastrointestinal and immune systems.
Dr. C. Girish, the lead scientist in the discussion of the hepatoprotective effect, wrote, " The regulation of the gastrointestinal system may improve the general well-being of the patients, as well as improvement of constipation, may prevent the absorption of harmful substances and indirectly decrease ascites (Langmead and Rampton, 2001). The protection of liver cells against toxic materials including drugs, lipid peroxidation, and free radical injury may decrease inflammation, improve liver blood flow, and ultimately help in the reduction of ascites and blood pressure (Yang et al., 2000)".
In other words, herbal medicine expressed liver protection not only by improving the blood flow to the liver but also through regulating the gastrointestinal system against the building up toxins in the induction of free radicals and suppressing the normal function of the liver, and improving the immune system against inflammation induced the lipid oxidation.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, and wound healing agent, and to treat flatulence, bloating, appetite loss, ulcers, eczema, inflammations, etc.
In finding a potential ingredient for the protection of liver integrity, researchers examined curcumin, the active ingredient of turmeric's therapeutic potential for the treatment of liver disorders.
The application of curcumin showed liver protective activity by inhibiting the liver toxicity caused by long-term excessive alcohol drinking and acetaminophen, lindane, carbon tetrachloride (CCL4), and diethylnitrosamine.
Furthermore, curcumin also restored liver functioning in heavy metals-induced hepatotoxicities models.
In the nonalcoholic fatty liver disease (NAFLD), the most common cause of the chronic liver disease model, researchers examined the Bisdemethoxycurcumin (BDMC), a polyphenolic compound derived from the Curcumae Longae Rhizoma liver protective activity.
The study included C57BL/6J mice divided into five groups of normal (normal diet without any treatment), methionine choline-deficient (MCD)-diet (MCD diet only), MCD + silymarin (SIL) 100 mg/kg group, MCD + BDMC 100 mg/kg group, MCD + SIL 50 mg/kg + BDMC 50 mg/kg group.
BDMC protected the liver against fatty change compared to severe hepatic fatty accumulation in the MCD-diet group.
BDMC increased liver function significantly, compared to that of the loss of liver function in the MCD-diet group.
Most importantly, BDMC showed an inhibitory effect on liver lipogenesis by reducing associated gene expression caused by the MCD diet.
Moreover, combinations of BDMC with SIL had a synergistic effect against MCD-diet models.
Based on the findings, Dr. Kim SB, the lead scientist said, "Our findings indicate that BDMC has a potential suppressive effect on NAFLD. Therefore, our data suggest that BDMC may act as a novel and potent therapeutic agent against NAFLD".
Taken altogether, turmeric and its bioactive compound curcumin may be considered a remedy for the improvement of liver function, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects by Khan H1, Ullah H2, Nabavi SM. (PubMed)
(2) Hepatoprotective Effect and Synergism of Bisdemethoxycurcumin against MCD Diet-Induced Nonalcoholic Fatty Liver Disease in Mice.
Kim SB1, Kang OH1, Lee YS2, Han SH3, Ahn YS3, Cha SW3, Seo YS1, Kong R2, Kwon DY. (PubMed)
(3) Herbal Drugs on the Liver by C. Girish, S.C. Pradhan, in Liver Pathophysiology, 2017, (Science Direct)
#ManukaHoney Inhibits Acute and Chronic #InflammatoryDiseases Through Its Antioxidant Activity, Researchers Suggest
Kyle J. Norton
Honey may be the next pharmaceutical target to identify the single ingredient medicine for the treatment of choric inflammatory disease, some scientists suggested.
Inflammation is a natural and systematic response of the immune system to the protection of the body against infection caused by the invasion of stimuli and pathogens.
After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulate the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms which may cause harm to our body.
In this acute phase of the battle, most of the time is won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead to the death of nearby healthy cells and improper skin healing with the formation of scars.
In some cases, certain proteins with duo anti and proinflammatory function also can switch to pro-inflammatory cytokines depending on the severity of the infection.
Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.
Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frames of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.
In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.
Dr. Philip Hunter in the study "The inflammation theory of disease" pinpointed the important cause of diseases associated with chronic inflammation, "Maria Abreu's research group at the University of Miami's Miller School of Medicine in the USA found that the incidence of colon cancer was linked directly to the expression of the Toll-like receptor 4 (TLR4) gene".
"TLRs are crucial in alerting the immune system to microbial infection, triggering acute inflammatory responses that clear invading pathogens. However, TLR4 can also maintain chronic inflammation, for example by responding to commensal bacteria in the gut. As such bacteria are constantly replenished through food intake, and therefore cannot be permanently cleared by the immune system, this can lead to persistent chronic infection maintained by TLRs. "
Honey is the miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one healthy sweet food for replacing the use of white sugar and artificial sweetener many people.
On finding an ingredient or whole food for the prevention and treatment of acute and chronic inflammatory diseases, scientists at Menoufia University examine the honey effects in a rat model of colitis induced by the injection of dextran sodium sulfate (DSS).
Application of natural honey showed a strong effect in the prevention of tissue injury and inflammatory infiltration by inhibited proteins associated with the production of proinflammatory cytokine and overexpression of reactive oxygen species.
Further examination of the honey effect, researchers indicated that the honey-treated group had significantly improved macroscopic and microscopic scores and inhibited the apoptotic markers.
At the end of the experiment, researchers said, "The beneficial role of natural honey in the treatment of DSS-induced colitis via the inhibition of colonic motor dysfunction and the inflammatory-oxidative-apoptotic cascade" and "the role of honey in epithelial regeneration was clarified", after taking into account co and confounders.
Moreover, in order to understand the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats, researchers examined the joint studies led by King Abdulaziz University, including 4 our groups of rats randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.
During the stud, Manuka honey treated group displayed a significantly decreased the ulcer index, completely protected the mucosa from lesions, and preserved gastric mucosal glycoprotein.\
Manuka honey treated group also showed increased levels of antioxidants enzymes which were suppressed by the injection of ethanol into an induced ulcer.
Manuka honey also decreased gastric mucosal MDA, the oxidative stress marker, and the plasma of proinflammatory cytokines.
Dr. Almasaudi SB, the lead scientist wrote in the final report, "Manuka honey likely exerted its antiulcer, effect by keeping enzymatic (GPx and SOD) and non-enzymatic (GSH and NO) antioxidants as well as inflammatory cytokines (TNF-α, IL-1β, and IL-6) in a reduced form, inhibited lipid peroxidation (MDA), and preserved mucous glycoproteins levels".
Taken together, Manuka honey may be considered a functional food for the prevention of inflammation and combined with the primary medicine for the treatment of chronic inflammatory diseases with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis by Nooh HZ1, Nour-Eldien NM2.(PubMed)
(2) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(3) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
Honey may be the next pharmaceutical target to identify the single ingredient medicine for the treatment of choric inflammatory disease, some scientists suggested.
Inflammation is a natural and systematic response of the immune system to the protection of the body against infection caused by the invasion of stimuli and pathogens.
After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulate the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms which may cause harm to our body.
In this acute phase of the battle, most of the time is won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead to the death of nearby healthy cells and improper skin healing with the formation of scars.
In some cases, certain proteins with duo anti and proinflammatory function also can switch to pro-inflammatory cytokines depending on the severity of the infection.
Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.
Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frames of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.
In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.
Dr. Philip Hunter in the study "The inflammation theory of disease" pinpointed the important cause of diseases associated with chronic inflammation, "Maria Abreu's research group at the University of Miami's Miller School of Medicine in the USA found that the incidence of colon cancer was linked directly to the expression of the Toll-like receptor 4 (TLR4) gene".
"TLRs are crucial in alerting the immune system to microbial infection, triggering acute inflammatory responses that clear invading pathogens. However, TLR4 can also maintain chronic inflammation, for example by responding to commensal bacteria in the gut. As such bacteria are constantly replenished through food intake, and therefore cannot be permanently cleared by the immune system, this can lead to persistent chronic infection maintained by TLRs. "
Honey is the miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one healthy sweet food for replacing the use of white sugar and artificial sweetener many people.
On finding an ingredient or whole food for the prevention and treatment of acute and chronic inflammatory diseases, scientists at Menoufia University examine the honey effects in a rat model of colitis induced by the injection of dextran sodium sulfate (DSS).
Application of natural honey showed a strong effect in the prevention of tissue injury and inflammatory infiltration by inhibited proteins associated with the production of proinflammatory cytokine and overexpression of reactive oxygen species.
Further examination of the honey effect, researchers indicated that the honey-treated group had significantly improved macroscopic and microscopic scores and inhibited the apoptotic markers.
At the end of the experiment, researchers said, "The beneficial role of natural honey in the treatment of DSS-induced colitis via the inhibition of colonic motor dysfunction and the inflammatory-oxidative-apoptotic cascade" and "the role of honey in epithelial regeneration was clarified", after taking into account co and confounders.
Moreover, in order to understand the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats, researchers examined the joint studies led by King Abdulaziz University, including 4 our groups of rats randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.
During the stud, Manuka honey treated group displayed a significantly decreased the ulcer index, completely protected the mucosa from lesions, and preserved gastric mucosal glycoprotein.\
Manuka honey treated group also showed increased levels of antioxidants enzymes which were suppressed by the injection of ethanol into an induced ulcer.
Manuka honey also decreased gastric mucosal MDA, the oxidative stress marker, and the plasma of proinflammatory cytokines.
Dr. Almasaudi SB, the lead scientist wrote in the final report, "Manuka honey likely exerted its antiulcer, effect by keeping enzymatic (GPx and SOD) and non-enzymatic (GSH and NO) antioxidants as well as inflammatory cytokines (TNF-α, IL-1β, and IL-6) in a reduced form, inhibited lipid peroxidation (MDA), and preserved mucous glycoproteins levels".
Taken together, Manuka honey may be considered a functional food for the prevention of inflammation and combined with the primary medicine for the treatment of chronic inflammatory diseases with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis by Nooh HZ1, Nour-Eldien NM2.(PubMed)
(2) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(3) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
#Chastetreeberry Extracts Shows A Strong Effect for the Treatment of #PremenstrualSyndrome, #PremenstrualDysphoricdisorder, and LatentHyperprolactinemia, According to Studies
Kyle J. Norton
Hyperprolinaemia is a condition characterized by overexpression of the level of prolactin in the blood produced by the lactotroph cells of the anterior pituitary gland.
Normally, the expression of the hormone prolactin is to enhance breast development during pregnancy and to induce lactation.
In non-pregnant women, elevated levels of prolactin can disrupt the normal menstrual period in women, causing the complication of infertility, abnormal lactation, amenorrhea, irregular periods, breast pain, and painful sexual intercourse.
The most common cause of the onset of hyperlactatemia is the result of the growth of a tumor on the pituitary gland. Most cases of the pituitary gland are noninvasive, however, if the tumor is growing large enough, it can suppress the nearby nerve cells, causing headaches and vision problems.
Some researchers suggested the syndrome can also be caused by the long-term use of certain medications.
Dr. Daria La Torre, the lead author in the study "Pharmacological causes of hyperprolactinemia" said, "Several drugs may determine a significant increase in prolactin serum concentration that is frequently associated with symptoms. The so-called typical antipsychotics are frequently responsible for drug-related hyperprolactinemia"
And, "Risperidone is one of the atypical neuroleptics most likely to induce hyperprolactinemia, while other atypical drugs are infrequently and only transiently associated with the increase of prolactin levels" and "Antidepressant drugs with serotoninergic activity, including selective serotonin reuptake inhibitors (SSRI), monoamine oxidase inhibitors (MAO-I) and some tricyclics, can cause hyperprolactinemia.".
Therefore, if you are taking the above medication, please make sure you discuss the problem with your doctor.
In fact, some women experience the syndrome of hyperprolactinemia with unknown causes.
Most common conventional treatments target the symptoms and reduce the size of the tumor. The unknown causes of hyperprolactinemia are treated with synthetic thyroid hormone.
Medication used for the treatment of hyperprolactinemia includes Medical treatment of dopamine agonists (DA): bromocriptine, lisuride, quinagolide, and cabergoline. And in over 80% of cases, these drugs induce normal prolactinoma and ovulatory cycles.
If you are taking one of these medications for the treatment of hyperprolactinemia, please make you know all the side effects
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region,.
The plant has been used in herbal medicine for thousands of years as an anaphrodisiac herb and is considered a Queen herb in treating menstrual problems and discomforts by taking it for a prolonged period of time.
There was a report that chaste tree berry stems and leaves were used by women as bedding "to cool the heat of lust" during the time of the Thesmophoria.
With an aim to reaffirm the traditional use of Vitex agnus-castus L. (chaste tree; chaste berry for the treatment of a range of female reproductive conditions in Anglo-American and European practice, researchers at the Royal Melbourne Institute of Technology-University conducted an experiment to examine the effect of the herbal medicine in women with premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinemia.
The search based on the Cochrane risk of bias and Jadad scales on the database of medical literature identifies 13 Thirteen randomized, controlled trials and twelve are included in this review, of which eight investigated premenstrual syndrome, two premenstrual dysphoric disorder, and two latent hyperprolactinemia.
Application of the Vitex agnus-castus in latent hyperprolactinemia suggested that the herbal medicine is superior compared to placebo for reducing TRH-stimulated prolactin secretion, normalizing a shortened luteal phase, increasing mid-luteal progesterone and 17β-oestradiol levels.
And Vitex is comparable to bromocriptine for reducing serum prolactin levels and ameliorating cyclic mastalgia. Adverse events with Vitex were mild and generally infrequent.
These results indicated, Vitex extracts in the treatment of premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinemia.
Furthermore, Dr, Milewicz A, in the finding natural medicine with no side effect in the treatment of hyperprolactinemia conducted a randomized double-blind study vs. placebo to evaluate the efficacy of a Vitex agnus castus preparation (Strotan capsules) vs. placebo.
The clinical study involved 52 women with luteal phase defects due to latent hyperprolactinemia.
The participants were given a daily dose of one capsule (20 mg) Vitex agnus castus preparation and placebo.
In the assessment of the blood for hormonal analysis taken at days 5-8 and day 20 of the menstrual cycle before and after three months of therapy.
Women who were received the Vitex agnus castus preparation showed a reduction of prolactin release after 3 months.
The shortened luteal phases of these women were normalized and deficits in the luteal progesterone synthesis were eliminated.
These changes were significant and occurred only in the Vitex group.
Side effects were not seen during the experiment and two women treated with the Vitex agnus castus preparation got pregnant.
Taken altogether, Chaste tree berry (Vitex agnus-castus) may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of hyperprolactinemia
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources(1) Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials by van Die MD1, Burger HG, Teede HJ, Bone KM.(PubMed)
(2) [Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study].[Article in German] by Milewicz A1, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H.(PubMed)
(3) Pharmacological causes of hyperprolactinemia by bDaria La Torre and Alberto Falorni. (PMC)
Hyperprolinaemia is a condition characterized by overexpression of the level of prolactin in the blood produced by the lactotroph cells of the anterior pituitary gland.
Normally, the expression of the hormone prolactin is to enhance breast development during pregnancy and to induce lactation.
In non-pregnant women, elevated levels of prolactin can disrupt the normal menstrual period in women, causing the complication of infertility, abnormal lactation, amenorrhea, irregular periods, breast pain, and painful sexual intercourse.
The most common cause of the onset of hyperlactatemia is the result of the growth of a tumor on the pituitary gland. Most cases of the pituitary gland are noninvasive, however, if the tumor is growing large enough, it can suppress the nearby nerve cells, causing headaches and vision problems.
Some researchers suggested the syndrome can also be caused by the long-term use of certain medications.
Dr. Daria La Torre, the lead author in the study "Pharmacological causes of hyperprolactinemia" said, "Several drugs may determine a significant increase in prolactin serum concentration that is frequently associated with symptoms. The so-called typical antipsychotics are frequently responsible for drug-related hyperprolactinemia"
And, "Risperidone is one of the atypical neuroleptics most likely to induce hyperprolactinemia, while other atypical drugs are infrequently and only transiently associated with the increase of prolactin levels" and "Antidepressant drugs with serotoninergic activity, including selective serotonin reuptake inhibitors (SSRI), monoamine oxidase inhibitors (MAO-I) and some tricyclics, can cause hyperprolactinemia.".
Therefore, if you are taking the above medication, please make sure you discuss the problem with your doctor.
In fact, some women experience the syndrome of hyperprolactinemia with unknown causes.
Most common conventional treatments target the symptoms and reduce the size of the tumor. The unknown causes of hyperprolactinemia are treated with synthetic thyroid hormone.
Medication used for the treatment of hyperprolactinemia includes Medical treatment of dopamine agonists (DA): bromocriptine, lisuride, quinagolide, and cabergoline. And in over 80% of cases, these drugs induce normal prolactinoma and ovulatory cycles.
If you are taking one of these medications for the treatment of hyperprolactinemia, please make you know all the side effects
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region,.
The plant has been used in herbal medicine for thousands of years as an anaphrodisiac herb and is considered a Queen herb in treating menstrual problems and discomforts by taking it for a prolonged period of time.
There was a report that chaste tree berry stems and leaves were used by women as bedding "to cool the heat of lust" during the time of the Thesmophoria.
With an aim to reaffirm the traditional use of Vitex agnus-castus L. (chaste tree; chaste berry for the treatment of a range of female reproductive conditions in Anglo-American and European practice, researchers at the Royal Melbourne Institute of Technology-University conducted an experiment to examine the effect of the herbal medicine in women with premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinemia.
The search based on the Cochrane risk of bias and Jadad scales on the database of medical literature identifies 13 Thirteen randomized, controlled trials and twelve are included in this review, of which eight investigated premenstrual syndrome, two premenstrual dysphoric disorder, and two latent hyperprolactinemia.
Application of the Vitex agnus-castus in latent hyperprolactinemia suggested that the herbal medicine is superior compared to placebo for reducing TRH-stimulated prolactin secretion, normalizing a shortened luteal phase, increasing mid-luteal progesterone and 17β-oestradiol levels.
And Vitex is comparable to bromocriptine for reducing serum prolactin levels and ameliorating cyclic mastalgia. Adverse events with Vitex were mild and generally infrequent.
These results indicated, Vitex extracts in the treatment of premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinemia.
Furthermore, Dr, Milewicz A, in the finding natural medicine with no side effect in the treatment of hyperprolactinemia conducted a randomized double-blind study vs. placebo to evaluate the efficacy of a Vitex agnus castus preparation (Strotan capsules) vs. placebo.
The clinical study involved 52 women with luteal phase defects due to latent hyperprolactinemia.
The participants were given a daily dose of one capsule (20 mg) Vitex agnus castus preparation and placebo.
In the assessment of the blood for hormonal analysis taken at days 5-8 and day 20 of the menstrual cycle before and after three months of therapy.
Women who were received the Vitex agnus castus preparation showed a reduction of prolactin release after 3 months.
The shortened luteal phases of these women were normalized and deficits in the luteal progesterone synthesis were eliminated.
These changes were significant and occurred only in the Vitex group.
Side effects were not seen during the experiment and two women treated with the Vitex agnus castus preparation got pregnant.
Taken altogether, Chaste tree berry (Vitex agnus-castus) may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of hyperprolactinemia
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources(1) Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials by van Die MD1, Burger HG, Teede HJ, Bone KM.(PubMed)
(2) [Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study].[Article in German] by Milewicz A1, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H.(PubMed)
(3) Pharmacological causes of hyperprolactinemia by bDaria La Torre and Alberto Falorni. (PMC)
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