By Kyle J. Norton
Dysmenorrhea is a painful period during menstruation, affecting many women in their reproductive years.
There are 2 types of dysmenorrhea
* Primary dysmenorrhea is a condition with no underlying cause for menstrual cramps or difficult menstruation occurring just before or during menstruation. The condition affects 90% of girls in the first 2 years of menstruation causing immature reproductive organs.
* Secondary dysmenorrhea is a medical condition characterized by gynecological diseases, including hormone imbalance, endometriosis, fibromas, pelvic inflammatory disease, etc.
Conventionally, most cases of primary dysmenorrhea are treated with NSAIDs nonsteroid anti-inflammatory medicine, or birth control pill with an aim to reduce pain without affecting daily activity.
However, the intake of such medicines often causes some side effects. Therefore, if you are currently taking one of the aforementioned drugs, please make sure you know all the side effects for preventive measures.
According to the study, approximately, 43% of premenopausal women in the US have painful menstruation in every menstrual period, and 41% have pain in some periods.
However, by evaluating the characteristics of dysmenorrhea the prevalence rate is actually 25%.
Dr. Giovanni Grandi, the lead scientist in the analysis of the prevalence of menstrual pain in young women said, "Menstrual pain is a very common problem, but the need for medication and the inability to function normally occurs less frequently. Nevertheless, at least one in four women experience distressing menstrual pain characterized by a need for medication and absenteeism from study or social activities".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the treatment of painful periods with no side effects examined the comparative efficacy of ginger on progressive muscle relaxation and symptoms of dysmenorrhoea among nursing students of Pune, Maharashtra
The study included 75 nursing students divided into three groups, two experimental and one control.
Ginger powder 1 gm per dose was administered twice a day with warm water after a meal to the second experimental group during the first three days of their menstruation.
According to the 5-point Likert Scale used to assess the severity of selected symptoms of dysmenorrhoea, the ginger powder group showed a significant reduction of symptoms of dysmenorrhoea, particularly in progressive muscle relaxation.
Furthermore, in order to reveal more information about a ginger anti painful period activity, researchers compared the effect of mefenamic acid and ginger on pain management in primary dysmenorrhea.
This randomized clinical trial included 122 female students with moderate to severe primary dysmenorrhea randomly allocated to the ginger and mefenamic groups
The mefenamic group received 250 mg capsules every 8 h, and the ginger group received 250 mg capsules every 6 h from the onset of menstruation until pain relief lasted 2 cycles.
According to the results, both the mefenamic and ginger groups exerted similar effects in reducing symptoms of pain in the second month.
The severity of dysmenorrhea, pain duration, cycle duration, and bleeding volume were not significantly different between groups during the study.
However, the menstrual days were more in the ginger group in the first and second cycles.
Based on the findings, researchers wrote, "Ginger is as effective as mefenamic acid on pain relief in primary dysmenorrhea. Ginger does not have adverse effects and is an alternative treatment for primary dysmenorrhea".
Taken together, ginger may be considered a functional alternative for the prevention and treatment of dysmenorrhea, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial by Shirvani MA1, Motahari-Tabari N, Alipour A. (PubMed)
(2) Effect of progressive muscle relaxation versus intake of ginger powder on dysmenorrhoea amongst the nursing students in Pune by Halder A. (PubMed)
(2) Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial by Rahnama P1, Montazeri A, Huseini HF, Kianbakht S, Naseri M.(PubMed)
(3) Prevalence of menstrual pain in young women: what is dysmenorrhea? by Giovanni Grandi, Serena Ferrari, Anjeza Xholli, Marianna Cannoletta, Federica Palma, Cecilia Romani, Annibale Volpe, and Angelo Cagnacci. (PMC)
Thursday, 22 June 2023
#Herbal #Bilberry Inhibits the Levels of #Ceruloplasmin Associated with the Onset of InflammatoryDiseases, Researchers Find
Kyle J. Norton
Nutrigenomic activity is a scientific term that optimizes the interaction of nutrition and genes, especially in the prevention or treatment of disease.
In other words, the nutrigenomic activity provided information on how the interaction of certain foods with specific genes leads to the increased risk of chronic diseases such as type 2 diabetes, obesity, heart disease, stroke, and certain cancers.
Biologically, nutrigenomics also provided information molecularly how chemicals found in the diet altered the expression of genes that affect individual health.
More precisely, nutrigenomics is depending totally on an individual's genetic makeup.
Dr. Praveen Sharma, the lead scientist in the examination of the nutrigenomics and nutrigenetics effect in disease prevention and cure wrote, "Nutrigenomics is providing the effects of ingested nutrients and other food components on gene expression and gene regulation, i.e., diet-gene interaction in order to identify the dietetic components having beneficial or detrimental health effects".
And, " Like Phenylketonuria (PKU) an inborn error of metabolism which is caused by a change (mutation) in a single gene. Diagnosed individuals have to avoid food containing the amino acid phenylalanine".
Bilberry is a species of low-growing shrub in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
On finding a natural plant-based compound for the interaction of nutrients and gene expression, researchers compared the nutrigenomic activity on diet supplements of Echinacea angustifolia (EA, 0.10mg/kg live weight as echinacoside; 14 dogs), Vaccinium myrtillus (VM, 0.20mg/kg live weight as anthocyanidin, 13 dogs), Curcuma longa (CL, 6.60mg/kg live weight as curcumin, 18 dogs with arthrosis), and Sylibum marianum (SM, 1.5mg/kg live weight as sylibin, 8 dogs with hepatopathy).
24 healthy dogs selected for the study were fed with a control diet (CT) and the experimental groups received for 60 days the same diet supplements aforementioned with nutraceuticals.
VM significantly inhibited the gene expression associated with the production of a pro-inflammatory cytokine and chemokine such as TNF, IL-8, and PTGS2 prostaglandin-endoperoxide synthase 2, compared to other treatment groups.
IL-8 is a protein or gene or a chemokine (Small cytokines) produced by immune white blood cell macrophages and other cell types such as epithelial cells, airway smooth muscle cells, and endothelial cells.
Furthermore, VM also inhibited the overexpression of factor-kappa B1 (NFKB1) which plays a critical role in the immune response to oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products, leading to diseases associated with inflammation and inappropriate immune cell development or delayed cell growth.
In other words, bilberry modulates the immune response through the needs and protection of the body.
Ceruloplasmin is a glycoprotein produced in the liver, high levels of CuCp is associated with inflammatory diseases such as rheumatoid arthritis and infection such as lymphoma.
In other words, VM promotes the production of antioxidant enzymes in the host body against the induction of oxidative stress by modulating the immune response.
Dr. Sgorlon S, the lead scientist said, "Nutraceutical administrations in dogs can be an interesting approach to modulate the immune response in order to improve the health condition of animals".
Taken altogether, bilberry may be considered a functioning remedy for the improvement of gene expression against diseases involving overexpression of immune response, pending the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Nutrigenomic activity of plant-derived compounds in health and disease: Results of a dietary intervention study in a dog by Sgorlon S1, Stefanon B2, Sandri M2, Colitti M. (PubMed)
(2) Nutrigenomics and Nutrigenetics: New Insight in Disease Prevention and Cure by Praveen Sharma and Shailendra Dwivedi. (Indian Journal of Clinical Biochemistry)
Nutrigenomic activity is a scientific term that optimizes the interaction of nutrition and genes, especially in the prevention or treatment of disease.
In other words, the nutrigenomic activity provided information on how the interaction of certain foods with specific genes leads to the increased risk of chronic diseases such as type 2 diabetes, obesity, heart disease, stroke, and certain cancers.
Biologically, nutrigenomics also provided information molecularly how chemicals found in the diet altered the expression of genes that affect individual health.
More precisely, nutrigenomics is depending totally on an individual's genetic makeup.
Dr. Praveen Sharma, the lead scientist in the examination of the nutrigenomics and nutrigenetics effect in disease prevention and cure wrote, "Nutrigenomics is providing the effects of ingested nutrients and other food components on gene expression and gene regulation, i.e., diet-gene interaction in order to identify the dietetic components having beneficial or detrimental health effects".
And, " Like Phenylketonuria (PKU) an inborn error of metabolism which is caused by a change (mutation) in a single gene. Diagnosed individuals have to avoid food containing the amino acid phenylalanine".
Bilberry is a species of low-growing shrub in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, psoriasis, diabetes, etc.
On finding a natural plant-based compound for the interaction of nutrients and gene expression, researchers compared the nutrigenomic activity on diet supplements of Echinacea angustifolia (EA, 0.10mg/kg live weight as echinacoside; 14 dogs), Vaccinium myrtillus (VM, 0.20mg/kg live weight as anthocyanidin, 13 dogs), Curcuma longa (CL, 6.60mg/kg live weight as curcumin, 18 dogs with arthrosis), and Sylibum marianum (SM, 1.5mg/kg live weight as sylibin, 8 dogs with hepatopathy).
24 healthy dogs selected for the study were fed with a control diet (CT) and the experimental groups received for 60 days the same diet supplements aforementioned with nutraceuticals.
VM significantly inhibited the gene expression associated with the production of a pro-inflammatory cytokine and chemokine such as TNF, IL-8, and PTGS2 prostaglandin-endoperoxide synthase 2, compared to other treatment groups.
IL-8 is a protein or gene or a chemokine (Small cytokines) produced by immune white blood cell macrophages and other cell types such as epithelial cells, airway smooth muscle cells, and endothelial cells.
Furthermore, VM also inhibited the overexpression of factor-kappa B1 (NFKB1) which plays a critical role in the immune response to oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products, leading to diseases associated with inflammation and inappropriate immune cell development or delayed cell growth.
In other words, bilberry modulates the immune response through the needs and protection of the body.
Ceruloplasmin is a glycoprotein produced in the liver, high levels of CuCp is associated with inflammatory diseases such as rheumatoid arthritis and infection such as lymphoma.
In other words, VM promotes the production of antioxidant enzymes in the host body against the induction of oxidative stress by modulating the immune response.
Dr. Sgorlon S, the lead scientist said, "Nutraceutical administrations in dogs can be an interesting approach to modulate the immune response in order to improve the health condition of animals".
Taken altogether, bilberry may be considered a functioning remedy for the improvement of gene expression against diseases involving overexpression of immune response, pending the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Nutrigenomic activity of plant-derived compounds in health and disease: Results of a dietary intervention study in a dog by Sgorlon S1, Stefanon B2, Sandri M2, Colitti M. (PubMed)
(2) Nutrigenomics and Nutrigenetics: New Insight in Disease Prevention and Cure by Praveen Sharma and Shailendra Dwivedi. (Indian Journal of Clinical Biochemistry)
Herbal #Ginger Detoxes the Liver Against Xenobiotic Hepatotoxicity-Induced Liver Damage, According to Studies
Kyle J. Norton
The functions of the liver are to filter out blood coming from the digestive tract, before passing it to the rest of the body.
In another world, the liver inhibits chemical toxins and other harmful by-products such as medication before distributing clean blood to nourish the body.
In detail, the liver also plays a critical role in bile production for the digestive system in breaking down food, excretion of bilirubin to clear waste products, production of cholesterol for building the cell wall membrane, and vitamin D secretion as well as steroid hormones.
According to the statistics, provided by the World Health Organization, liver diseases affect the largest population worldwide, representing 46% of global diseases.
Out of 35 million people in the world die of chronic diseases, 59% are liver diseases and 59% of the mortality is because of chronic diseases.
Jaundice, persistent abdominal pain and swelling, swelling in the legs and ankles, chronic fatigue and gastrointestinal discomforts, particularly persistent itchy skin, dark urine color, and pale stool are some common signs and symptoms of liver problems.
Although there are many risk factors associated with the onset of liver diseases, excessive alcohol drinking may be the major cause of liver diseases in the Western world, besides hepatitis C infection.
Dr. Radan Bruha, in the evaluation of alcoholic liver diseases, wrote, "Alcohol consumption is directly associated with liver disease mortality and accounts for elevated social and economic costs. Alcoholic liver disease (ALD) may take the form of acute involvement (alcoholic hepatitis) or chronic liver disease (steatosis, steatohepatitis, fibrosis, and cirrhosis)".
And, " The severity and prognosis of alcohol-induced liver disease depend on the amount, pattern and duration of alcohol consumption, as well as on the presence of liver inflammation, diet, nutritional status and genetic predisposition of an individual. While steatosis is an almost completely benign disease, liver cirrhosis is associated with marked morbidity, mortality, and life expectancy shortening. The median survival of patients with advanced cirrhosis is 1-2 years. Severe acute alcoholic hepatitis (AH) is associated with mortality as high as 50%".
The results strongly suggested that excessive alcohol drinking over time will definitely cause alcoholic liver disease.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Scientists on finding a natural remedy in improving liver functionings examined the effects of 6-gingerol on the biochemical parameters and ovarian histological improvements in estradiol valerate (EV) induced PCOS rats.
36 female Wistar rats included in the study were divided into 4 groups: control, received normal diet, PCOS control, received 4 mg/kg EV injection for 28 days and two experimental groups, received an EV injection for 28 days and followed by 6-gingerol (200 μg/kg and 400 μg/kg) for 14 days.
Before application of 6-gingerol, group administrated by EV showed an increase of body and ovarian weights, abnormality in serum sex steroid profile and proinflammatory cytokines and a decrease of antioxidant activity associated to the increase of total cholesterol (TC), low-density cholesterol (LDL-C), triglycerides.
However, pretreatment 6-gingerol treatments, particularly the 400 μg/kg dose, restored the alteration back to normal and improved liver in the regulation of lipid profile.
The findings suggested that 6-gingerol processed beneficial effects in PCOS rats by inhibiting oxidative stress and restoring biochemical parameters to normal and decreasing the cysts in the ovaries and increasing liver functioning.
In order to reveal more information of ginger effect on the liver, researchers also reviewed the liver protective activity of polyphenol-rich food products (e.g., chokeberry, black and green tea, blueberry, olive oil, rosemary, and ginger) from this xenobiotic hepatotoxicity and treatment of this heavy metal-induced liver damage.
Injection of polyphenols showed a strong effect in binding ions of Cd against Cd in the induction of hepatotoxicity.
Although most studies are conducted in animal models, some of them are derived from experimental models that reflect human exposure. Therefore it is safe to assume that some polyphenol-rich food products may be promising protective agents against Cd hepatotoxicity in humans, including ginger.
Taken altogether, ginger used alone or combined with other polyphenol-rich foods may be considered functional remedies for improving the liver functioning with no side effects, pending to the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The effects of 6-Gingerol on reproductive improvement, liver functioning and Cyclooxygenase-2 gene expression in estradiol valerate - Induced polycystic ovary syndrome in Wistar rats by Pournaderi PS1, Yaghmaei P2, Khodaei H3, Noormohammadi Z1, Hejazi SH4. (PubMed)
(2) Review of polyphenol-rich products as potential protective and therapeutic factors against cadmium hepatotoxicity by Mężyńska M1, Brzóska MM1. (PubMed)
(3) Alcoholic liver disease by Radan Bruha, Karel Dvorak, and Jaromir Petrtyl. (PMC)
The functions of the liver are to filter out blood coming from the digestive tract, before passing it to the rest of the body.
In another world, the liver inhibits chemical toxins and other harmful by-products such as medication before distributing clean blood to nourish the body.
In detail, the liver also plays a critical role in bile production for the digestive system in breaking down food, excretion of bilirubin to clear waste products, production of cholesterol for building the cell wall membrane, and vitamin D secretion as well as steroid hormones.
According to the statistics, provided by the World Health Organization, liver diseases affect the largest population worldwide, representing 46% of global diseases.
Out of 35 million people in the world die of chronic diseases, 59% are liver diseases and 59% of the mortality is because of chronic diseases.
Jaundice, persistent abdominal pain and swelling, swelling in the legs and ankles, chronic fatigue and gastrointestinal discomforts, particularly persistent itchy skin, dark urine color, and pale stool are some common signs and symptoms of liver problems.
Although there are many risk factors associated with the onset of liver diseases, excessive alcohol drinking may be the major cause of liver diseases in the Western world, besides hepatitis C infection.
Dr. Radan Bruha, in the evaluation of alcoholic liver diseases, wrote, "Alcohol consumption is directly associated with liver disease mortality and accounts for elevated social and economic costs. Alcoholic liver disease (ALD) may take the form of acute involvement (alcoholic hepatitis) or chronic liver disease (steatosis, steatohepatitis, fibrosis, and cirrhosis)".
And, " The severity and prognosis of alcohol-induced liver disease depend on the amount, pattern and duration of alcohol consumption, as well as on the presence of liver inflammation, diet, nutritional status and genetic predisposition of an individual. While steatosis is an almost completely benign disease, liver cirrhosis is associated with marked morbidity, mortality, and life expectancy shortening. The median survival of patients with advanced cirrhosis is 1-2 years. Severe acute alcoholic hepatitis (AH) is associated with mortality as high as 50%".
The results strongly suggested that excessive alcohol drinking over time will definitely cause alcoholic liver disease.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Scientists on finding a natural remedy in improving liver functionings examined the effects of 6-gingerol on the biochemical parameters and ovarian histological improvements in estradiol valerate (EV) induced PCOS rats.
36 female Wistar rats included in the study were divided into 4 groups: control, received normal diet, PCOS control, received 4 mg/kg EV injection for 28 days and two experimental groups, received an EV injection for 28 days and followed by 6-gingerol (200 μg/kg and 400 μg/kg) for 14 days.
Before application of 6-gingerol, group administrated by EV showed an increase of body and ovarian weights, abnormality in serum sex steroid profile and proinflammatory cytokines and a decrease of antioxidant activity associated to the increase of total cholesterol (TC), low-density cholesterol (LDL-C), triglycerides.
However, pretreatment 6-gingerol treatments, particularly the 400 μg/kg dose, restored the alteration back to normal and improved liver in the regulation of lipid profile.
The findings suggested that 6-gingerol processed beneficial effects in PCOS rats by inhibiting oxidative stress and restoring biochemical parameters to normal and decreasing the cysts in the ovaries and increasing liver functioning.
In order to reveal more information of ginger effect on the liver, researchers also reviewed the liver protective activity of polyphenol-rich food products (e.g., chokeberry, black and green tea, blueberry, olive oil, rosemary, and ginger) from this xenobiotic hepatotoxicity and treatment of this heavy metal-induced liver damage.
Injection of polyphenols showed a strong effect in binding ions of Cd against Cd in the induction of hepatotoxicity.
Although most studies are conducted in animal models, some of them are derived from experimental models that reflect human exposure. Therefore it is safe to assume that some polyphenol-rich food products may be promising protective agents against Cd hepatotoxicity in humans, including ginger.
Taken altogether, ginger used alone or combined with other polyphenol-rich foods may be considered functional remedies for improving the liver functioning with no side effects, pending to the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The effects of 6-Gingerol on reproductive improvement, liver functioning and Cyclooxygenase-2 gene expression in estradiol valerate - Induced polycystic ovary syndrome in Wistar rats by Pournaderi PS1, Yaghmaei P2, Khodaei H3, Noormohammadi Z1, Hejazi SH4. (PubMed)
(2) Review of polyphenol-rich products as potential protective and therapeutic factors against cadmium hepatotoxicity by Mężyńska M1, Brzóska MM1. (PubMed)
(3) Alcoholic liver disease by Radan Bruha, Karel Dvorak, and Jaromir Petrtyl. (PMC)
Bilberry Processes Anti Alzheimer's disease by Decreasing the Levels of Soluble Aβ40 and Aβ42 in Vivos
Kyle J. Norton
Alzheimer's disease is a chronic neurodegenerative disease caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.
The disease is most prevalent in the elderly and causes over 60% of all cases of dementia.
According to the statistics, approximately 5.7 million Americans of all ages have Alzheimer's. 15.9 million family caregivers provided an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.
Epidemiological studies suggested that Alzheimer's disease is caused by a combination of genetic, lifestyle and environmental factors that affect the neurons of the brain over time.
Although, less 10% of patients with AD are associated with a genetic preposition. Patients with such a mutated gene are virtually guaranteed to develop the disease.
More precisely, any one of a number of different single-gene mutations on chromosomes 21, 14, and 1 was found to induce the onset of AD.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Researchers on finding a natural compound for the treatment of Alzheimer's disease (AD) investigated the effects of anthocyanoside extracts (Vaccinium myrtillus anthocyanoside (VMA)) obtained from bilberry on the in vitro progression of Aβ fibril formation and in vivo effects of this compound on AD pathogenesis.
In Neuro2a cells, injection of VMA inhibited the in vitro formation of Aβ peptide fibrils in the induction of neurons toxicity.
Furthermore, A diet containing 1% VMA prevented the cognitive degeneration found in the tested AD mice.
Interestingly, this diet in the retention of cognitive ability was not accompanied by a reduction in the aggregate deposition in brains but rather, an increase in insoluble deposits, compared to control mice.
The results suggested that VMA shows a strong effect on Alzheimer's disease by altering the Aβ aggregation to a non-toxic form.
In order to reveal more information about bilberry anti-AD activity, researchers elucidated the effects of different polyphenols on neuroprotection and APP processing under different in vitro stress conditions.
Injection of myricetin, quercetin or anthocyanin-rich extracts in a dose-dependent manner significantly inhibited the overexpression of free radicals caused by the application of Menadione.
APdE9 mice fed with anthocyanin-rich bilberry or blackcurrant extracts showed decreased APP C-terminal fragment levels, the amyloid precursor protein in the cerebral cortex, compared to APdE9 mice on the control diet.
Levels of soluble Aβ40 and Aβ42 levels were found to significantly decrease in bilberry-fed mice, compared to blackcurrant-fed mice.
Additionally, bilberry diet also improved the spatial working memory of aged APdE9 mice, compared to mice on the control diet.
Based on the findings, Dr. Vepsäläinen S, the lead scientist wrote in the final report, "These data suggest that anthocyanin-rich bilberry and blackcurrant diets favorably modulate APP processing and alleviate behavioral abnormalities in a mouse model of AD".
Taken altogether, bilberry rich in Anthocyanin may be considered a functional remedy for the prevention and treatment of Alzheimer's disease (AD), pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anthocyanin suppresses the toxicity of Aβ deposits through diversion of molecular forms in vitro and in vivo models of Alzheimer's disease by Yamakawa MY, Uchino K, Watanabe Y, Adachi T, Nakanishi M, Ichino H, Hongo K, Mizobata T, Kobayashi S, Nakashima K, Kawata Y. (PubMed)
(2) Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease by Vepsäläinen S1, Koivisto H, Pekkarinen E, Mäkinen P, Dobson G, McDougall GJ, Stewart D, Haapasalo A, Karjalainen RO, Tanila H, Hiltunen M. (PubMed)
Alzheimer's disease is a chronic neurodegenerative disease caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.
The disease is most prevalent in the elderly and causes over 60% of all cases of dementia.
According to the statistics, approximately 5.7 million Americans of all ages have Alzheimer's. 15.9 million family caregivers provided an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.
Epidemiological studies suggested that Alzheimer's disease is caused by a combination of genetic, lifestyle and environmental factors that affect the neurons of the brain over time.
Although, less 10% of patients with AD are associated with a genetic preposition. Patients with such a mutated gene are virtually guaranteed to develop the disease.
More precisely, any one of a number of different single-gene mutations on chromosomes 21, 14, and 1 was found to induce the onset of AD.
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
Researchers on finding a natural compound for the treatment of Alzheimer's disease (AD) investigated the effects of anthocyanoside extracts (Vaccinium myrtillus anthocyanoside (VMA)) obtained from bilberry on the in vitro progression of Aβ fibril formation and in vivo effects of this compound on AD pathogenesis.
In Neuro2a cells, injection of VMA inhibited the in vitro formation of Aβ peptide fibrils in the induction of neurons toxicity.
Furthermore, A diet containing 1% VMA prevented the cognitive degeneration found in the tested AD mice.
Interestingly, this diet in the retention of cognitive ability was not accompanied by a reduction in the aggregate deposition in brains but rather, an increase in insoluble deposits, compared to control mice.
The results suggested that VMA shows a strong effect on Alzheimer's disease by altering the Aβ aggregation to a non-toxic form.
In order to reveal more information about bilberry anti-AD activity, researchers elucidated the effects of different polyphenols on neuroprotection and APP processing under different in vitro stress conditions.
Injection of myricetin, quercetin or anthocyanin-rich extracts in a dose-dependent manner significantly inhibited the overexpression of free radicals caused by the application of Menadione.
APdE9 mice fed with anthocyanin-rich bilberry or blackcurrant extracts showed decreased APP C-terminal fragment levels, the amyloid precursor protein in the cerebral cortex, compared to APdE9 mice on the control diet.
Levels of soluble Aβ40 and Aβ42 levels were found to significantly decrease in bilberry-fed mice, compared to blackcurrant-fed mice.
Additionally, bilberry diet also improved the spatial working memory of aged APdE9 mice, compared to mice on the control diet.
Based on the findings, Dr. Vepsäläinen S, the lead scientist wrote in the final report, "These data suggest that anthocyanin-rich bilberry and blackcurrant diets favorably modulate APP processing and alleviate behavioral abnormalities in a mouse model of AD".
Taken altogether, bilberry rich in Anthocyanin may be considered a functional remedy for the prevention and treatment of Alzheimer's disease (AD), pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anthocyanin suppresses the toxicity of Aβ deposits through diversion of molecular forms in vitro and in vivo models of Alzheimer's disease by Yamakawa MY, Uchino K, Watanabe Y, Adachi T, Nakanishi M, Ichino H, Hongo K, Mizobata T, Kobayashi S, Nakashima K, Kawata Y. (PubMed)
(2) Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease by Vepsäläinen S1, Koivisto H, Pekkarinen E, Mäkinen P, Dobson G, McDougall GJ, Stewart D, Haapasalo A, Karjalainen RO, Tanila H, Hiltunen M. (PubMed)
#Artichoke Processes Anti #Cancer Property by Improving the Function of Gene Associated with Tumor Expression and Antibodies
Kyle J. Norton
Cancer is a group of diseases caused by cell growth disorderly and uncontrollably in the tissue of the affected organs.
Cancers are caused by the alternation of cell DNA. What influences the change of a cell's DNA?
Epidemiological studies suggested that certain risk factors such as age, family and personal history, ethnicity, exposure to toxic chemicals, unhealthy lifestyle,... the list goes on and on, but no one can explain why people with the same health conditions in the same family, some are susceptible to cancer while others do not.
Furthermore, most people with some of the risk factors have never developed cancer.
Most general symptoms shared by all cancers are unintended weight loss, loss of appetite, fatigue, tiredness, and gastrointestinal discomforts.
Some researchers suggested that a weakened immune system due to reduced expression of proteins associated with tumor suppression and cell death programming such as p53 and overexpression of protein-involved cell cycle division such as cyclin.
Dr. Alexandre Corthay in the examination of the risk of cancer in patients with weakened immune systems explained "Here, I present eight types of evidence in support of the cancer immunosurveillance hypothesis.
* First, primary immunodeficiency in mice and humans is associated with increased cancer risk.
*Second, organ transplant recipients, who are treated with immunosuppressive drugs, are more prone to cancer development.
*Third, acquired immunodeficiency due to infection by the human immunodeficiency virus (HIV-1) leads to an elevated risk of cancer.
*Fourth, the quantity and quality of the immune cell infiltrate found in human primary tumors represent an independent prognostic factor for patient survival.
*Fifth, cancer cells harbor mutations in protein-coding genes that are specifically recognized by the adaptive immune system.
*Sixth, cancer cells selectively accumulate mutations to evade immune destruction (“immunoediting”).
*Seventh, lymphocytes bearing the NKG2D receptor are able to recognize and eliminate stressed premalignant cells.
*Eighth, a promising strategy to treat cancer consists in potentiating the naturally occurring immune response of the patient, through blockade of the immune checkpoint molecules CTLA-4, PD-1, or PD-L1".
The results clearly suggested that if you have a strong immune system, your risk of cancer is decreased substantially,
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Researchers on finding potential and natural ingredients as a human antibody against cancer, researchers examined the p19 silencing suppressor gene from artichoke in the tumor-associated antigen tenascin-C (TNC).
P19 silencing suppressor gene from artichoke inhibited the expression of the virus by raising the antibody expression levels by an order of magnitude (yields of purified H10, 50-100 mg/kg fresh weight).
Moreover, approximately 75% of purified protein consisted of full-sized antibodies functionally binding to Tenascin-C against the specific accumulation around tumor blood vessels, according to the immunohistochemical analysis of tumor tissues.
Tenascin-C (TNC) is highly expressed in cancer tissues.
Dr. Villani ME the lead scientist said, "The data indicate that the purification yields of mAb H10, using a transient expression system boosted by the p19 silencing suppressor, are exceptionally high when compared with the results reported previously, providing a technique for the over-expression of anticancer".
In other words, artichokes improved the function of a gene associated with tumor expression and antibodies for the treatment of cancer.
Furthermore, the active product isolated from the Jerusalem artichoke tubers obtained after wound-drought stress used for the treatment of cancers also to exhibited free radical expression in the induction of cytotoxicity against cancer cell line, through its 18-kDa polypeptide and 28-kDa polypeptide,
Where 18-kDa polypeptide exerted a similar effect as a superoxide dismutase (SOD)and 28-kDa polypeptide to the alkaline phosphatase (AP).
Dr. and colleagues said, in the final report. "The superoxide dismutase polypeptide was shown to be involved in the antitumor activity, but the presence of smaller factors (MW<10 kDa), such as salicylic acid, can enhance this activity".
Taken altogether, artichoke may be considered for the prevention and treatment of cancer, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Plant pharming of a full-sized, tumour-targeting antibody using different expression strategies by Villani ME1, Morgun B, Brunetti P, Marusic C, Lombardi R, Pisoni I, Bacci C, Desiderio A, Benvenuto E, Donini M. (PubMed)
(2) Stressed Jerusalem artichoke tubers (Helianthus tuberosus L.) excrete a protein fraction with specific cytotoxicity on plant and animal tumour cell by Griffaut B1, Debiton E, Madelmont JC, Maurizis JC, Ledoigt G. (PubMed)
(3) Does the Immune System Naturally Protect Against Cancer? by Alexandre Corthay. (PMC)
Cancer is a group of diseases caused by cell growth disorderly and uncontrollably in the tissue of the affected organs.
Cancers are caused by the alternation of cell DNA. What influences the change of a cell's DNA?
Epidemiological studies suggested that certain risk factors such as age, family and personal history, ethnicity, exposure to toxic chemicals, unhealthy lifestyle,... the list goes on and on, but no one can explain why people with the same health conditions in the same family, some are susceptible to cancer while others do not.
Furthermore, most people with some of the risk factors have never developed cancer.
Most general symptoms shared by all cancers are unintended weight loss, loss of appetite, fatigue, tiredness, and gastrointestinal discomforts.
Some researchers suggested that a weakened immune system due to reduced expression of proteins associated with tumor suppression and cell death programming such as p53 and overexpression of protein-involved cell cycle division such as cyclin.
Dr. Alexandre Corthay in the examination of the risk of cancer in patients with weakened immune systems explained "Here, I present eight types of evidence in support of the cancer immunosurveillance hypothesis.
* First, primary immunodeficiency in mice and humans is associated with increased cancer risk.
*Second, organ transplant recipients, who are treated with immunosuppressive drugs, are more prone to cancer development.
*Third, acquired immunodeficiency due to infection by the human immunodeficiency virus (HIV-1) leads to an elevated risk of cancer.
*Fourth, the quantity and quality of the immune cell infiltrate found in human primary tumors represent an independent prognostic factor for patient survival.
*Fifth, cancer cells harbor mutations in protein-coding genes that are specifically recognized by the adaptive immune system.
*Sixth, cancer cells selectively accumulate mutations to evade immune destruction (“immunoediting”).
*Seventh, lymphocytes bearing the NKG2D receptor are able to recognize and eliminate stressed premalignant cells.
*Eighth, a promising strategy to treat cancer consists in potentiating the naturally occurring immune response of the patient, through blockade of the immune checkpoint molecules CTLA-4, PD-1, or PD-L1".
The results clearly suggested that if you have a strong immune system, your risk of cancer is decreased substantially,
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Researchers on finding potential and natural ingredients as a human antibody against cancer, researchers examined the p19 silencing suppressor gene from artichoke in the tumor-associated antigen tenascin-C (TNC).
P19 silencing suppressor gene from artichoke inhibited the expression of the virus by raising the antibody expression levels by an order of magnitude (yields of purified H10, 50-100 mg/kg fresh weight).
Moreover, approximately 75% of purified protein consisted of full-sized antibodies functionally binding to Tenascin-C against the specific accumulation around tumor blood vessels, according to the immunohistochemical analysis of tumor tissues.
Tenascin-C (TNC) is highly expressed in cancer tissues.
Dr. Villani ME the lead scientist said, "The data indicate that the purification yields of mAb H10, using a transient expression system boosted by the p19 silencing suppressor, are exceptionally high when compared with the results reported previously, providing a technique for the over-expression of anticancer".
In other words, artichokes improved the function of a gene associated with tumor expression and antibodies for the treatment of cancer.
Furthermore, the active product isolated from the Jerusalem artichoke tubers obtained after wound-drought stress used for the treatment of cancers also to exhibited free radical expression in the induction of cytotoxicity against cancer cell line, through its 18-kDa polypeptide and 28-kDa polypeptide,
Where 18-kDa polypeptide exerted a similar effect as a superoxide dismutase (SOD)and 28-kDa polypeptide to the alkaline phosphatase (AP).
Dr. and colleagues said, in the final report. "The superoxide dismutase polypeptide was shown to be involved in the antitumor activity, but the presence of smaller factors (MW<10 kDa), such as salicylic acid, can enhance this activity".
Taken altogether, artichoke may be considered for the prevention and treatment of cancer, pending the confirmation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Plant pharming of a full-sized, tumour-targeting antibody using different expression strategies by Villani ME1, Morgun B, Brunetti P, Marusic C, Lombardi R, Pisoni I, Bacci C, Desiderio A, Benvenuto E, Donini M. (PubMed)
(2) Stressed Jerusalem artichoke tubers (Helianthus tuberosus L.) excrete a protein fraction with specific cytotoxicity on plant and animal tumour cell by Griffaut B1, Debiton E, Madelmont JC, Maurizis JC, Ledoigt G. (PubMed)
(3) Does the Immune System Naturally Protect Against Cancer? by Alexandre Corthay. (PMC)
#Healthyfood #Ginger Enhances Memory, Increases Neuronal Density, and Decreases AChE Activity and Oxidativestress Status
Kyle J. Norton
Neurological disorders are a group of diseases associated with the neurons in the brain and spinal cord of the central nervous system.
The WHO in the evaluation of neurological disorder wrote, "Neurological disorders contribute to 92 million disability-adjusted life years (DALYs) in 2005 projected to increase to 103 million in 2030 (approximately a 12% increase). While Alzheimer's and other dementias are projected to show a 66% increase from 2005 to 2030".
Where one DALY represents the loss of the equivalent of one year of full health.
Believe or not, there are more than 600 diseases of the central nervous system, including brain tumors, epilepsy, dementia such as Parkinson's disease and Alzheimer's disease, and stroke.
The top 3 neurological diseases include
* Alzheimer's disease (AD) is a neurodegenerative disease in the elderly, associated with the worsening of memory, thinking, and behavior that severe enough to affect language communication, memory, lifelong hobbies, or social life
* Bell's Palsy is a condition caused by sudden weakness or paralysis of facial muscles on one side of the face.
* Cerebral Palsy is a neurological disorder of children affecting a child's movement, motor skills, and muscle tone.
Conventionally, the treatment of neurological diseases is totally depending on the type of disease. However, the aim of the treatment is to improve quality of life, including lifestyle change, therapy to reduce the symptoms and restore some functions, pain relief, and medication to control the progression of the disease.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the treatment of neurological disorders with no side effects investigated the ginger effects on age-related neurological disorders (ANDs), including neurodegenerative diseases, which are multifactorial disorders with a risk that increases with aging.
According to the analysis of the structure-activity relationships of ginger phytochemicals, ginger was effective for the treatment of ANDs by targeting different ligand sites.
Furthermore, ginger and its constituents, such as 6-gingerol, 6-shogaol, 6-paradol, zingerone, and dehydrozingerone, are effective for ameliorating the neurological symptoms and pathological conditions of ANDs by modulating cell death or cell survival signaling molecules, observed through assay differentiation.
Based on these results, researchers in a joint study led by Kyung Hee University, wrote, "We conclude that the active ingredients in ginger have therapeutic potential in ANDs".
Moreover, in order to reveal more information on the ginger anti ANDs property, researchers investigated the combined extract of Cyperus rotundus and Zingiber officinale (CP1) on the improvement of age-related dementia in rats with AF64A-induced memory deficits.
The study included male Wistar rats weighing 180-200 g orally given CP1 at doses of 100, 200, and 300 mg.kg-1 BW for a period of 14 days after bilateral intracerebroventricular administration of AF64A.
CP1 administration enhanced memory, increased neuronal density, and decreased AChE activity and oxidative stress status, as observed by the tested assays.
CP1 protected neuron's integrity and viability by activating the protein associated with the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
Dr. Sutalangka C, the lead scientist in the neurological team wrote, "These results suggested that CP1 might improve memory via enhanced cholinergic function and decreased neurodegeneration and oxidative stress".
Taken together, ginger may be considered a functional alternative for the prevention and treatment of neurological disorders, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Pharmacotherapeutic potential of ginger and its compounds in age-related neurological disorders by Choi JG1, Kim SY2, Jeong M2, Oh MS. (PubMed)
(2) Neuroprotective and cognitive-enhancing effects of the combined extract of Cyperus rotundus and Zingiber officinale by Sutalangka C1,2, Wattanathorn J. (PubMed)
(3) NEUROLOGICAL DISORDERS public health challenges by the WHO
Neurological disorders are a group of diseases associated with the neurons in the brain and spinal cord of the central nervous system.
The WHO in the evaluation of neurological disorder wrote, "Neurological disorders contribute to 92 million disability-adjusted life years (DALYs) in 2005 projected to increase to 103 million in 2030 (approximately a 12% increase). While Alzheimer's and other dementias are projected to show a 66% increase from 2005 to 2030".
Where one DALY represents the loss of the equivalent of one year of full health.
Believe or not, there are more than 600 diseases of the central nervous system, including brain tumors, epilepsy, dementia such as Parkinson's disease and Alzheimer's disease, and stroke.
The top 3 neurological diseases include
* Alzheimer's disease (AD) is a neurodegenerative disease in the elderly, associated with the worsening of memory, thinking, and behavior that severe enough to affect language communication, memory, lifelong hobbies, or social life
* Bell's Palsy is a condition caused by sudden weakness or paralysis of facial muscles on one side of the face.
* Cerebral Palsy is a neurological disorder of children affecting a child's movement, motor skills, and muscle tone.
Conventionally, the treatment of neurological diseases is totally depending on the type of disease. However, the aim of the treatment is to improve quality of life, including lifestyle change, therapy to reduce the symptoms and restore some functions, pain relief, and medication to control the progression of the disease.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the treatment of neurological disorders with no side effects investigated the ginger effects on age-related neurological disorders (ANDs), including neurodegenerative diseases, which are multifactorial disorders with a risk that increases with aging.
According to the analysis of the structure-activity relationships of ginger phytochemicals, ginger was effective for the treatment of ANDs by targeting different ligand sites.
Furthermore, ginger and its constituents, such as 6-gingerol, 6-shogaol, 6-paradol, zingerone, and dehydrozingerone, are effective for ameliorating the neurological symptoms and pathological conditions of ANDs by modulating cell death or cell survival signaling molecules, observed through assay differentiation.
Based on these results, researchers in a joint study led by Kyung Hee University, wrote, "We conclude that the active ingredients in ginger have therapeutic potential in ANDs".
Moreover, in order to reveal more information on the ginger anti ANDs property, researchers investigated the combined extract of Cyperus rotundus and Zingiber officinale (CP1) on the improvement of age-related dementia in rats with AF64A-induced memory deficits.
The study included male Wistar rats weighing 180-200 g orally given CP1 at doses of 100, 200, and 300 mg.kg-1 BW for a period of 14 days after bilateral intracerebroventricular administration of AF64A.
CP1 administration enhanced memory, increased neuronal density, and decreased AChE activity and oxidative stress status, as observed by the tested assays.
CP1 protected neuron's integrity and viability by activating the protein associated with the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
Dr. Sutalangka C, the lead scientist in the neurological team wrote, "These results suggested that CP1 might improve memory via enhanced cholinergic function and decreased neurodegeneration and oxidative stress".
Taken together, ginger may be considered a functional alternative for the prevention and treatment of neurological disorders, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Pharmacotherapeutic potential of ginger and its compounds in age-related neurological disorders by Choi JG1, Kim SY2, Jeong M2, Oh MS. (PubMed)
(2) Neuroprotective and cognitive-enhancing effects of the combined extract of Cyperus rotundus and Zingiber officinale by Sutalangka C1,2, Wattanathorn J. (PubMed)
(3) NEUROLOGICAL DISORDERS public health challenges by the WHO
#Yoga Inhibits Parameters Associated with the Promotion of Aging Progression, According to Studies
Kyle J. Norton
Yoga may have a profound and positive effect in delaying the aging process, some renowned institute studies suggested.
Aging is a natural process of growing old.
Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been well-known for people in the Western world and some parts of Asia due to health benefits reported by various respectable institutes research and supported by health advocates.
According to the study to explore the impact of yoga and meditation-based lifestyle intervention (YMLI) on cellular aging in 96 healthy individuals randomly assigned to a 12-weeks of YMLI, at the end of 12 weeks of the lesson, the YMLI group expressed significant improvements in both the cardinal biomarkers of cellular aging and the metabotropic biomarkers influencing cellular aging compared to baseline values.
The efficacy of the program in the reduced cellular aging process was attributed to the activities in decreased production of ROS and pro-inflammatory cytokine and the hormone cortisol, increased mean values of telomerase activity in the regulated aging process, and hormone β-endorphin in reduced stress and maintain homeostasis.
Dr. Madhuri Tolahunase, the led author, after taking into account of other co-founders, said, "Lifestyle is an integrated entity, and an intervention, like YMLI, that has overall positive influence on our health appears most useful versus changing only one aspect at a time, as is seen by action of certain drugs. Yoga is holistic and mind-body medicine and is more beneficial and advantageous than individual interventions like physical exercise, caloric restriction, and antioxidants".
Other researchers, in the study of yoga breathing in protected skin against aging, filed the following results
1. Yoga breathing reduced psychological aspects of stress and anxiety which have been found to associate with promoted aging
2. Yoga also expressed an impact in regulated advanced glycation end products (AGE) which have recently been shown to play a role in tissue aging
3. Comprehensive yoga program including breathing and meditative exercises may have a profound effect in enhanced gene expression involving oxidative stress, DNA damage, cell cycle control, aging, and apoptosis and
4. Detoxification
In further analysis, Dr, Beri K the lead author said, "(Contract to general belief)The interesting correlation of insulin regulation and glucose control can be translated to improvement and maybe reversal of the effects on AGE protein accumulation in the body tissue".
In support of the above differentiation, Dr. Brown RP at the Columbia University College of Physicians and Surgeons launched an investigation of yoga breathing in the delayed aging process, suggested that
1. Yoga breathing (pranayama) can have a significant and positive effect in bringing the mind to the present moment and reduce stress
2. Yoga breathing delayed the aging process through reduced expression of depression, anxiety, and post-traumatic stress disorder, and for victims of mass disasters.
3. The practices also relieved many forms of suffering.
Finally, after taking into account other risk factors, researchers concluded that yoga breathing can affect longevity mechanisms.
Taken together, Yoga used alone or combined with meditation may have a therapeutic effect in delaying aging by regulating cellular and psychological expressions.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Impact of Yoga and Meditation on Cellular Aging in Apparently Healthy Individuals: A Prospective, Open-Label Single-Arm Exploratory Study by Tolahunase M1, Sagar R2, Dada R1.(PubMed)
(2) Breathing to younger skin: 'Reversing the molecular mechanism of skin aging with yoga' by Beri K1. (PMC)
(3) Yoga breathing, meditation, and longevity by Brown RP1, Gerbarg PL. (PubMed)
Yoga may have a profound and positive effect in delaying the aging process, some renowned institute studies suggested.
Aging is a natural process of growing old.
Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been well-known for people in the Western world and some parts of Asia due to health benefits reported by various respectable institutes research and supported by health advocates.
According to the study to explore the impact of yoga and meditation-based lifestyle intervention (YMLI) on cellular aging in 96 healthy individuals randomly assigned to a 12-weeks of YMLI, at the end of 12 weeks of the lesson, the YMLI group expressed significant improvements in both the cardinal biomarkers of cellular aging and the metabotropic biomarkers influencing cellular aging compared to baseline values.
The efficacy of the program in the reduced cellular aging process was attributed to the activities in decreased production of ROS and pro-inflammatory cytokine and the hormone cortisol, increased mean values of telomerase activity in the regulated aging process, and hormone β-endorphin in reduced stress and maintain homeostasis.
Dr. Madhuri Tolahunase, the led author, after taking into account of other co-founders, said, "Lifestyle is an integrated entity, and an intervention, like YMLI, that has overall positive influence on our health appears most useful versus changing only one aspect at a time, as is seen by action of certain drugs. Yoga is holistic and mind-body medicine and is more beneficial and advantageous than individual interventions like physical exercise, caloric restriction, and antioxidants".
Other researchers, in the study of yoga breathing in protected skin against aging, filed the following results
1. Yoga breathing reduced psychological aspects of stress and anxiety which have been found to associate with promoted aging
2. Yoga also expressed an impact in regulated advanced glycation end products (AGE) which have recently been shown to play a role in tissue aging
3. Comprehensive yoga program including breathing and meditative exercises may have a profound effect in enhanced gene expression involving oxidative stress, DNA damage, cell cycle control, aging, and apoptosis and
4. Detoxification
In further analysis, Dr, Beri K the lead author said, "(Contract to general belief)The interesting correlation of insulin regulation and glucose control can be translated to improvement and maybe reversal of the effects on AGE protein accumulation in the body tissue".
In support of the above differentiation, Dr. Brown RP at the Columbia University College of Physicians and Surgeons launched an investigation of yoga breathing in the delayed aging process, suggested that
1. Yoga breathing (pranayama) can have a significant and positive effect in bringing the mind to the present moment and reduce stress
2. Yoga breathing delayed the aging process through reduced expression of depression, anxiety, and post-traumatic stress disorder, and for victims of mass disasters.
3. The practices also relieved many forms of suffering.
Finally, after taking into account other risk factors, researchers concluded that yoga breathing can affect longevity mechanisms.
Taken together, Yoga used alone or combined with meditation may have a therapeutic effect in delaying aging by regulating cellular and psychological expressions.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Impact of Yoga and Meditation on Cellular Aging in Apparently Healthy Individuals: A Prospective, Open-Label Single-Arm Exploratory Study by Tolahunase M1, Sagar R2, Dada R1.(PubMed)
(2) Breathing to younger skin: 'Reversing the molecular mechanism of skin aging with yoga' by Beri K1. (PMC)
(3) Yoga breathing, meditation, and longevity by Brown RP1, Gerbarg PL. (PubMed)
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