Kyle J. Norton
Cardiovascular diseases (CVD) are a group of medical conditions associated with blood vessels and the heart.
Depending on the location of blood flow is blocked, cardiovascular diseases can be classified into
Heart disease, including
* Heart disease affects heart chambers
Heart failure is caused by the heart not pumping as much blood as it should.
* Heart disease affects heart muscles
The heart muscles thicken and become stiff, increasing the amount of pressure required to expand for blood flow into the heart or the narrowing of the passage as a result of obstructing blood flow out of the heart.
* Heart disease affects heart valves
These types of heart diseases occur when the mitral valve in the heart is narrowing causing the heart to work harder to pump blood from the left atrium into the ventricle.
* Heart disease affecting coronary arteries and coronary veins
The malfunctioning of the heart may be due to heart muscle damage caused by narrowed or blocked arteries.
5. Heart disease affects heart lining
Rheumatic heart disease results from inflammation of the heart lining when too much fluid builds up in the lungs leading to pulmonary congestion.
6. Heart disease affects the electrical system
The electrical system within the heart is responsible for ensuring the heart beats correctly. Any malfunction of the electrical system in the heart causes a fast, slow, or irregular heartbeat.
and stroke, including
* Ischemic stroke caused by a clot or other blockage within an artery leading to the brain.
* Hemorrhagic stroke is caused by the vessel in the brain rupturing that leads to blood leaking into the brain.
According to statistics provided by the CDC, approximately, 600,000 people die of heart disease in the US every year, according to 1 in every 4 deaths. Heart disease is the leading cause of death for both men and women.
On the other hand, more than 795,000 people in the United States have a stroke every year, including 610,000 with a first or new stroke. 87% of all strokes are ischemic strokes.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
In seeking a potential compound for the treatment of cardiovascular disease, researchers investigated whether the dietary supplement (bromelain) has the potential to reduce plasma fibrinogen and other cardiovascular disease (CVD) risk factors in patients with diabetes.
The 12 weeks randomized placebo-controlled, double-blind, parallel design, efficacy study was carried out in China including 68 Chinese diabetic patients [32 males and 36 females; Han origin, the mean age of 61.26 years (standard deviation (SD), 12.62 years)] with at least one CVD risk factor.
Patients were randomized into either a bromelain or placebo group. While the bromelain group received a bromelain capsule(1,050 mg, taken (2×350 mg) after breakfast and another (350 mg) after dinner, the placebo group received a placebo capsule that consisted of an inert ingredient with no treatment effect.
According to the tested assays, the bromelain group at the end of the study showed a mean reduction of 0.13 g/L of fibrinogen level, compared with the mean reduction of 0.36 g/L in the placebo group.
Although there is no difference in mean change in other CVD risk factors (blood lipids, blood pressure), blood glucose, C-reactive protein, and anthropometric measures, however, according to the additional examination, researchers found statistical differences in fibrinogen may have influenced the results of bromelain effects on CVD.
In order to reveal more information about bromelain anti-CVD activity, researchers launched a study by reviewing the correlated study on online medical literature.
According to the results of 6 papers that met the inclusion criteria out of 223 papers retrieved, bromelain showed a significant effect on acute thrombophlebitis, by decreasing aggregation of blood platelets.
Futhermore, the injection of bromelain also exhibited a cardioprotective effect, by ameliorating rejection-induced arterial wall remodeling, preventing thrombin-induced human platelet aggregation, and reducing thrombus formation.
Taken altogether, bromelain may be considered a supplement for the prevention of cardiovascular disease, pending the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Bromelain and cardiovascular risk factors in diabetes: An exploratory randomized, placebo-controlled, double-blind clinical trial by Ley CM1, Ni Q2, Liao X3, Gao HL4, Robinson N. (PubMed)
(2) A review of the use of bromelain in cardiovascular diseases by Ley CM1, Tsiami A, Ni Q, Robinson N. (PubMed)
Wednesday, 21 June 2023
#Indicaxanthin Blocks the #Opoptosis of #Macrophages that Elevate the Plaque Progression to Causes #Atherosclerosis, Researcher Show
Kyle J. Norton
Atherosclerosis is a medical condition caused by plaque accumulated on the wall of arteries, leading to the narrowing of the artery and reducing oxygen risk blood flow to the heart and brain.
Depending on the location of the blockage, if the reduced blood flow occurred in the brain, it will cause the death of the brain cells, leading to stroke.
However, if the reduced blood flow occurred in the heart, it will cause damage to the heart tissues, leading to heart disease.
The most common disease associated with atherosclerosis is coronary artery disease. Plaques are made up of cholesterol, calcium, and other chemical substances in the artery
Most people with atherosclerosis are asymptomatic at the early stage.
Some researchers suggested that atherosclerosis is a lipoprotein-driven disease. Therefore, people with high blood cholesterol are at an increased risk of atherosclerosis. Overuse of calcium supplements is also found to elevate the condition risk, particularly in the elderly.
Other risk factors that have been found epidemiologically by studies are high blood pressure, triglycerides, smoking, insulin resistance, obesity or diabetes, and inflammatory diseases, such as arthritis, lupus, or infections.
Most cases of atherosclerosis can be reversed by making a change of lifestyle and moderate exercise.
Dr. Singh RB, the lead scientist wrote, "Adherence to diet and exercise was obtained through questionnaires, and information obtained was quantified into a formula. After 24 weeks, the overall score of diet and exercises were significantly higher in group A(intervention diet( than in group B(control). There was a significant decrease in serum total cholesterol (13.3%), low-density lipoprotein cholesterol (16.9%), triglycerides (19.2%), fasting blood glucose (19.5%), and blood pressures (11.5/6.2 mm Hg) in the intervention group compared with initial levels and changes in group B".
Indicaxanthin is a phytochemical in the class of red and yellow indole-derived pigments of betacyanins, belonging to the group of betalains, found abundantly in beets, chard, etc.
With an aim to find a natural compound for the treatment of atherosclerosis, researchers at the Università di Palermo investigated the effect of phytochemical indicaxanthin (Ild) a major compound found in beetroot on human atheromas.
7-Ketocholesterol (7-KC)-induced the development of human atheromas, according to the kinetic measurements within 24 h, before injection of indicaxanthin showed the early formation of intracellular reactive oxygen species over basal levels, preceding NADPH oxidase-4 (NOX-4) over-expression and elevation of cytosolic Ca²⁺, involved in reactive oxygen species (ROS) production. and associated with the progressive depletion of the antioxidant activity of total thiols.
Furthermore, 7-KC- also induced the expression of NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) associated with the production of proinflammatory cytokines and innate and adaptive immune response.
Where 7-Ketocholesterol (7-KC) induced apoptosis of macrophages has been found to elevate the plaque progression and endoplasmic reticulum stress caused by secretion of pro-inflammatory, procoagulant, and proteolytic molecules by macrophages.
Believe it or not, Co-incubation of 2·5 μm of indicaxanthin completely prevented 7-KC-induced pro-apoptotic events.
In other words, indicaxanthin protects the macrophage's integrity against apoptosis, thus reducing the risk of plaque accumulated on the wall of the arteries in facilitating the onset of atherosclerosis.
Based on the findings, researchers concluded, "The effects of Ind may be ascribed to inhibition of NOX-4 basal activity and over-expression, inhibition of NF-κB activation, maintaining cell redox balance and Ca homeostasis, with the prevention of mitochondrial damage and consequently apoptosis".
Taken altogether, phytochemical indicaxanthin (Ild) found in beetroot may be considered supplements for the prevention and treatment of atherosclerosis, pending the confirmation of a larger sample size and multicenter human study.
Intake of indicaxanthin (Ild) in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phytochemical indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis by preventing cytosolic Ca(2+) increase and oxidative stress by Tesoriere L1, Attanzio A, Allegra M, Gentile C, Livrea MA. (PubMed)
(2) Betalains, the nature-inspired pigments, in health and diseases by Rahimi P1, Abedimanesh S1, Mesbah-Namin SA1, Ostadrahimi A. (PubMed)
(3) Effects of diet and lifestyle changes on atherosclerotic risk factors after 24 weeks on the Indian Diet Heart Study by Singh RB1, Singh NK, Rastogi SS, Mani UV, Niaz MA. (PubMed)
Atherosclerosis is a medical condition caused by plaque accumulated on the wall of arteries, leading to the narrowing of the artery and reducing oxygen risk blood flow to the heart and brain.
Depending on the location of the blockage, if the reduced blood flow occurred in the brain, it will cause the death of the brain cells, leading to stroke.
However, if the reduced blood flow occurred in the heart, it will cause damage to the heart tissues, leading to heart disease.
The most common disease associated with atherosclerosis is coronary artery disease. Plaques are made up of cholesterol, calcium, and other chemical substances in the artery
Most people with atherosclerosis are asymptomatic at the early stage.
Some researchers suggested that atherosclerosis is a lipoprotein-driven disease. Therefore, people with high blood cholesterol are at an increased risk of atherosclerosis. Overuse of calcium supplements is also found to elevate the condition risk, particularly in the elderly.
Other risk factors that have been found epidemiologically by studies are high blood pressure, triglycerides, smoking, insulin resistance, obesity or diabetes, and inflammatory diseases, such as arthritis, lupus, or infections.
Most cases of atherosclerosis can be reversed by making a change of lifestyle and moderate exercise.
Dr. Singh RB, the lead scientist wrote, "Adherence to diet and exercise was obtained through questionnaires, and information obtained was quantified into a formula. After 24 weeks, the overall score of diet and exercises were significantly higher in group A(intervention diet( than in group B(control). There was a significant decrease in serum total cholesterol (13.3%), low-density lipoprotein cholesterol (16.9%), triglycerides (19.2%), fasting blood glucose (19.5%), and blood pressures (11.5/6.2 mm Hg) in the intervention group compared with initial levels and changes in group B".
Indicaxanthin is a phytochemical in the class of red and yellow indole-derived pigments of betacyanins, belonging to the group of betalains, found abundantly in beets, chard, etc.
With an aim to find a natural compound for the treatment of atherosclerosis, researchers at the Università di Palermo investigated the effect of phytochemical indicaxanthin (Ild) a major compound found in beetroot on human atheromas.
7-Ketocholesterol (7-KC)-induced the development of human atheromas, according to the kinetic measurements within 24 h, before injection of indicaxanthin showed the early formation of intracellular reactive oxygen species over basal levels, preceding NADPH oxidase-4 (NOX-4) over-expression and elevation of cytosolic Ca²⁺, involved in reactive oxygen species (ROS) production. and associated with the progressive depletion of the antioxidant activity of total thiols.
Furthermore, 7-KC- also induced the expression of NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) associated with the production of proinflammatory cytokines and innate and adaptive immune response.
Where 7-Ketocholesterol (7-KC) induced apoptosis of macrophages has been found to elevate the plaque progression and endoplasmic reticulum stress caused by secretion of pro-inflammatory, procoagulant, and proteolytic molecules by macrophages.
Believe it or not, Co-incubation of 2·5 μm of indicaxanthin completely prevented 7-KC-induced pro-apoptotic events.
In other words, indicaxanthin protects the macrophage's integrity against apoptosis, thus reducing the risk of plaque accumulated on the wall of the arteries in facilitating the onset of atherosclerosis.
Based on the findings, researchers concluded, "The effects of Ind may be ascribed to inhibition of NOX-4 basal activity and over-expression, inhibition of NF-κB activation, maintaining cell redox balance and Ca homeostasis, with the prevention of mitochondrial damage and consequently apoptosis".
Taken altogether, phytochemical indicaxanthin (Ild) found in beetroot may be considered supplements for the prevention and treatment of atherosclerosis, pending the confirmation of a larger sample size and multicenter human study.
Intake of indicaxanthin (Ild) in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Phytochemical indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis by preventing cytosolic Ca(2+) increase and oxidative stress by Tesoriere L1, Attanzio A, Allegra M, Gentile C, Livrea MA. (PubMed)
(2) Betalains, the nature-inspired pigments, in health and diseases by Rahimi P1, Abedimanesh S1, Mesbah-Namin SA1, Ostadrahimi A. (PubMed)
(3) Effects of diet and lifestyle changes on atherosclerotic risk factors after 24 weeks on the Indian Diet Heart Study by Singh RB1, Singh NK, Rastogi SS, Mani UV, Niaz MA. (PubMed)
#RegularWalking Reduces the Risk of #Osteoporosis by Suppressing #BoneTurnover in Older Adults, Scientists Suggest
Kyle J. Norton
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, but the regular walking contribution to health benefits of the younger elderly has not been explored.
Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and is often associated with senescence invertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(1).
Regular walking has been shown to reduce the prevalence of osteoporosis in older adults by keeping older people mobile and independent(2). According to a joint study led by Manchester Metropolitan University, osteoporosis, and muscular weakness are decreased by regularly completing activities ranging from low-intensity walking(2).
The American College of Sports Medicine in the study of physical activity for older adults, suggested "(physical activity)improved bone health and, thus, reduction in risk for osteoporosis; improved postural stability, thereby reducing the risk of falling and associated injuries and fractures" and "The benefits associated with regular exercise and physical activity contribute to a more healthy, independent lifestyle, greatly improving the functional capacity and quality of life in this population"(3).
Dr. Buchner DM at the University of Washington School of Medicine said, "Epidemiologic evidence strongly supports the role of regular physical activity in successful aging by preserving muscle performance, promoting mobility, and reducing fall risk"(4).
In fact, exercisers with distance walked in six minutes, not only improved (p < .05) scores on an observational gait scale, Isokinetic strength in knee flexion(5), but also promoted suppression of bone turnover and reduced risk of osteoporosis, according to the study of 50 postmenopausal women, aged 49-75 years, with osteopenia/osteoporosis recruited: 32 women enter the exercise program (the exercise group) and 18 served as controls (the control group)(6).
Unfortunately, the University Department of Primary Care and Population Sciences after intensive studying of brisk walking in the prevention of postmenopausal osteoporosis. insisted that brisk walking in the older adult, although reduces the risk of bone turnover, it is associated with the risk of falling, according to the result of an investigation of 165 women drawn from the local accident and emergency departments with a history of fracture of an upper limb in the previous 2 years(7).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)
(2) Physical activity in older age: perspectives for healthy aging and frailty by McPhee JS1, French DP2, Jackson D3, Nazroo J4, Pendleton N5, Degens H6,7.(PubMed)
(3) American College of Sports Medicine Position Stand. Exercise and physical activity for older adults.[No authors listed](PubMed)
(4) Preserving mobility in older adults by Buchner DM1.(PubMed)
(5) Effects of a group exercise program on strength, mobility, and falls among fall-prone elderly men. by Rubenstein LZ1, Josephson KR, Trueblood PR, Loy S, Harker JO, Pietruszka FM, Robbins AS(PubMed)
(6) Effect of walking exercise on bone metabolism in postmenopausal women with osteopenia/osteoporosis by Yamazaki S1, Ichimura S, Iwamoto J, Takeda T, Toyama Y.(PubMed)
(7) Randomized placebo-controlled trial of brisk walking in the prevention of postmenopausal osteoporosis by Ebrahim S1, Thompson PW, Baskaran V, Evans K.(PubMed)
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, but the regular walking contribution to health benefits of the younger elderly has not been explored.
Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and is often associated with senescence invertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(1).
Regular walking has been shown to reduce the prevalence of osteoporosis in older adults by keeping older people mobile and independent(2). According to a joint study led by Manchester Metropolitan University, osteoporosis, and muscular weakness are decreased by regularly completing activities ranging from low-intensity walking(2).
The American College of Sports Medicine in the study of physical activity for older adults, suggested "(physical activity)improved bone health and, thus, reduction in risk for osteoporosis; improved postural stability, thereby reducing the risk of falling and associated injuries and fractures" and "The benefits associated with regular exercise and physical activity contribute to a more healthy, independent lifestyle, greatly improving the functional capacity and quality of life in this population"(3).
Dr. Buchner DM at the University of Washington School of Medicine said, "Epidemiologic evidence strongly supports the role of regular physical activity in successful aging by preserving muscle performance, promoting mobility, and reducing fall risk"(4).
In fact, exercisers with distance walked in six minutes, not only improved (p < .05) scores on an observational gait scale, Isokinetic strength in knee flexion(5), but also promoted suppression of bone turnover and reduced risk of osteoporosis, according to the study of 50 postmenopausal women, aged 49-75 years, with osteopenia/osteoporosis recruited: 32 women enter the exercise program (the exercise group) and 18 served as controls (the control group)(6).
Unfortunately, the University Department of Primary Care and Population Sciences after intensive studying of brisk walking in the prevention of postmenopausal osteoporosis. insisted that brisk walking in the older adult, although reduces the risk of bone turnover, it is associated with the risk of falling, according to the result of an investigation of 165 women drawn from the local accident and emergency departments with a history of fracture of an upper limb in the previous 2 years(7).
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)
(2) Physical activity in older age: perspectives for healthy aging and frailty by McPhee JS1, French DP2, Jackson D3, Nazroo J4, Pendleton N5, Degens H6,7.(PubMed)
(3) American College of Sports Medicine Position Stand. Exercise and physical activity for older adults.[No authors listed](PubMed)
(4) Preserving mobility in older adults by Buchner DM1.(PubMed)
(5) Effects of a group exercise program on strength, mobility, and falls among fall-prone elderly men. by Rubenstein LZ1, Josephson KR, Trueblood PR, Loy S, Harker JO, Pietruszka FM, Robbins AS(PubMed)
(6) Effect of walking exercise on bone metabolism in postmenopausal women with osteopenia/osteoporosis by Yamazaki S1, Ichimura S, Iwamoto J, Takeda T, Toyama Y.(PubMed)
(7) Randomized placebo-controlled trial of brisk walking in the prevention of postmenopausal osteoporosis by Ebrahim S1, Thompson PW, Baskaran V, Evans K.(PubMed)
#Artichoke Alleviates Symptoms and Improves the Quality of Life in Patients with #FunctionalDyspepsia (FD), Researchers say
Kyle J. Norton
Functional dyspepsia (FD) is a chronic condition characterized by a burning sensation caused by uncoordinated and ineffectual emptying of the upper digestive tract with no measurable structural abnormalities.
Functional dyspepsia (FD) is subdivided into two types: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS).
According to statistics, approximately 20-45% of Canadians have such a condition, but only a low percentage of patients seek help from physicians. and functional dyspepsia accounts for 62.5% of dyspepsia in a population of black African patients, compared to other races.
The exact causes of functional dyspepsia are unidentified. Some researchers suggested that excessive acid secretion, inflammation, food allergies, unhealthy lifestyle choice, and long-term use of medications may have strong implications for the onset of the syndrome.
Pain, digestive discomforts such as fullness and bloating, excessive burping, nausea, and sometimes vomiting GERD and a sour taste in the mouth are the most common symptoms of functional dyspepsia.
If you experience some of the aforementioned symptoms, please make sure you check with your doctor to rule out the possibility.
Some researchers suggested that unhealthy dietary habits are one of the major risk factors associated with the onset of FD in the world.
Dr. Ji-Hao Xu, the lead scientist in the assessment of dietary habits in the risk of FD, wrote, "Unhealthy dietary habits were more prevalent in the FD group than in the control groups (75.86% versus 37.50%; p<0.001). FD was found to be associated with irregular mealtime, dining out, fatty food, sweet food, and coffee (p<0.05). The impact of each dietary factor varied with FD subtypes".
And, "Certain types of dietary habits were positively correlated with the prevalence of FD. FD subtypes showed relatively different associations with dietary factors".
The finding strongly suggested by following a healthy diet pattern, FD may be preventable.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In the finding of natural therapeutics for the treatment of functional dyspepsia (FD), researchers compared the efficacy of ginger and artichoke supplementation (SG) versus placebo in the treatment of FD.
The prospective multicentre, double-blind, randomized, placebo-controlled, parallel-group comparison of the supplement and placebo over a period of 4 weeks included 126 FD patients given 2 capsules/day (before lunch and dinner (supplementation/placebo: 65/61).
After 14 days, supplement treatment showed a significant amelioration of FD, compared to the placebo.
SG treatment group also showed a significant reduction of nausea, epigastric fullness, epigastric pain, and bloating compared to placebo.
Dr.Giacosa A, the lead scientist wrote, "The association between ginger and artichoke leaf extracts appears safe and efficacious in the treatment of FD and could represent a promising treatment for this disease".
In order to reveal more information about artichoke anti-FD property, researchers assessed the efficacy of artichoke leaf extract (ALE) in the treatment of patients with functional dyspepsia (FD).
The double-blind, randomized controlled trial (RCT) included 247 patients with functional dyspepsia treated with either a commercial ALE preparation (2 x 320 mg plant extract t.d.s.) or a placebo.
ALE improved the overall symptom significantly over the 6 weeks compared to the placebo
Similarly, patients treated with ALE also showed significantly greater improvement in the global quality-of-life scores (NDI) compared to the placebo.
Dr. Holtmann G, the lead scientist after taking into account co and confounders wrote in the final report, "The ALE preparation tested was significantly better than the placebo in alleviating symptoms and improving the disease-specific quality of life in patients with functional dyspepsia".
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of functional dyspepsia (FD), pending the confirmation of a larger sample and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial by Giacosa A1, Guido D2, Grassi M2, Riva A3, Morazzoni P3, Bombardelli E3, Perna S4, Faliva MA4, Rondanelli M. (PubMed)
(2) Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial by Holtmann G1, Adam B, Haag S, Collet W, Grünewald E, Windeck T. (PubMed)
(3) Certain Dietary Habits Contribute to the Functional Dyspepsia in South China Rural Area by Xu JH1, Lai Y1, Zhuang LP2, Huang CZ1, Li CQ1, Chen QK1, Yu T1. (PubMed)
Functional dyspepsia (FD) is a chronic condition characterized by a burning sensation caused by uncoordinated and ineffectual emptying of the upper digestive tract with no measurable structural abnormalities.
Functional dyspepsia (FD) is subdivided into two types: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS).
According to statistics, approximately 20-45% of Canadians have such a condition, but only a low percentage of patients seek help from physicians. and functional dyspepsia accounts for 62.5% of dyspepsia in a population of black African patients, compared to other races.
The exact causes of functional dyspepsia are unidentified. Some researchers suggested that excessive acid secretion, inflammation, food allergies, unhealthy lifestyle choice, and long-term use of medications may have strong implications for the onset of the syndrome.
Pain, digestive discomforts such as fullness and bloating, excessive burping, nausea, and sometimes vomiting GERD and a sour taste in the mouth are the most common symptoms of functional dyspepsia.
If you experience some of the aforementioned symptoms, please make sure you check with your doctor to rule out the possibility.
Some researchers suggested that unhealthy dietary habits are one of the major risk factors associated with the onset of FD in the world.
Dr. Ji-Hao Xu, the lead scientist in the assessment of dietary habits in the risk of FD, wrote, "Unhealthy dietary habits were more prevalent in the FD group than in the control groups (75.86% versus 37.50%; p<0.001). FD was found to be associated with irregular mealtime, dining out, fatty food, sweet food, and coffee (p<0.05). The impact of each dietary factor varied with FD subtypes".
And, "Certain types of dietary habits were positively correlated with the prevalence of FD. FD subtypes showed relatively different associations with dietary factors".
The finding strongly suggested by following a healthy diet pattern, FD may be preventable.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In the finding of natural therapeutics for the treatment of functional dyspepsia (FD), researchers compared the efficacy of ginger and artichoke supplementation (SG) versus placebo in the treatment of FD.
The prospective multicentre, double-blind, randomized, placebo-controlled, parallel-group comparison of the supplement and placebo over a period of 4 weeks included 126 FD patients given 2 capsules/day (before lunch and dinner (supplementation/placebo: 65/61).
After 14 days, supplement treatment showed a significant amelioration of FD, compared to the placebo.
SG treatment group also showed a significant reduction of nausea, epigastric fullness, epigastric pain, and bloating compared to placebo.
Dr.Giacosa A, the lead scientist wrote, "The association between ginger and artichoke leaf extracts appears safe and efficacious in the treatment of FD and could represent a promising treatment for this disease".
In order to reveal more information about artichoke anti-FD property, researchers assessed the efficacy of artichoke leaf extract (ALE) in the treatment of patients with functional dyspepsia (FD).
The double-blind, randomized controlled trial (RCT) included 247 patients with functional dyspepsia treated with either a commercial ALE preparation (2 x 320 mg plant extract t.d.s.) or a placebo.
ALE improved the overall symptom significantly over the 6 weeks compared to the placebo
Similarly, patients treated with ALE also showed significantly greater improvement in the global quality-of-life scores (NDI) compared to the placebo.
Dr. Holtmann G, the lead scientist after taking into account co and confounders wrote in the final report, "The ALE preparation tested was significantly better than the placebo in alleviating symptoms and improving the disease-specific quality of life in patients with functional dyspepsia".
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of functional dyspepsia (FD), pending the confirmation of a larger sample and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial by Giacosa A1, Guido D2, Grassi M2, Riva A3, Morazzoni P3, Bombardelli E3, Perna S4, Faliva MA4, Rondanelli M. (PubMed)
(2) Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial by Holtmann G1, Adam B, Haag S, Collet W, Grünewald E, Windeck T. (PubMed)
(3) Certain Dietary Habits Contribute to the Functional Dyspepsia in South China Rural Area by Xu JH1, Lai Y1, Zhuang LP2, Huang CZ1, Li CQ1, Chen QK1, Yu T1. (PubMed)
#Yoga Induces Healing Process of the Whole Person--Mind, Body, and Spirit, According to Clinical Trials
Kyle J. Norton
Yoga may be one of the best practices to induce calmness for people who are in a state of constant pressure, some studies suggested
Yoga, the ancient practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known to people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes research and supported by health advocates.
In the study of 13 normal healthy adults to determine the effects of alternate nostril yoga breathing on (a) cerebral hemisphere asymmetry, and (b) changes in the standard EEG bands by assigning the participants into three sessions (a) alternate nostril yoga breathing (ANYB), (b) breath awareness and (c) quiet sitting, on separate days, researchers showed that alternate nostril yoga breathing (ANYB) expressed a higher result in induced calmness through stress and anxiety reduction.
Yoga alternate nostril breathing exercises demonstrated a significant effect on an individual's calmness under certain pressure, probably a result in the settle the mind and body, and emotions and decreased expression of an overactive or worrying mind.
Interestingly, certain posts in the sequence culminating in Padmasana(Lotus Pose) have been found to achieve a calm mind stage, according to the yoga journal.
Other researchers suggested that yoga's inner demonstration of calmness may also have a profound effect on the healing process of the whole person--mind, body, and spirit.
Dr. Ott MJ at the Dana Farber Cancer Institute, said, "Formal and informal daily practice fosters the development of profound inner calmness and nonreactivity of the mind, allowing individuals to face, and even embrace, all aspects of daily life, regardless of circumstances".
Indeed, yoga found the inner peace of participants through intimacy and the ability to listen to the body even in sadness, grief, and other festering emotions.
More importantly, in a study of 8 healthy male volunteers of the age group 25.9 +/- 3 (SD) years assigned to Santhi Kriya practice daily for 50 minutes for 30 days with the volunteer's body weight, blood pressure, oral temperature, pulse rate, respiration, ECG and EEG were recorded before and after the practice on the 1st day and subsequently on 10th, 20th and 30th day of their practice, researchers at the end of the experiment postulated that there was a gradual and significant decrease in the body weight and an increase in alpha activity of the brain (P less than 0.001) during the course of 30 days.
Further analysis also suggested that the increase of alpha activity both in the occipital and prefrontal areas of both the hemispheres of the brain indicated an increase in calmness.
More importantly, Santhi Kriya practice expressed an increase in oral temperature by 3 degrees F and a decreases respiratory rate significantly on all practice days.
Santhi Kriya yoga is a mixture of combined yogic practices of breathing and relaxation.
According to Dr. Richard P. Brown, Patricia L. Gerbarg, and Philip R. Muskin in the book of
How to Use Herbs, Nutrients, & Yoga in Mental Health, Santhi Kriya total cortical alpha activity in the brain is associated with relaxation calmness, and awareness, and the practice may be considered as an adjunct therapy to induce a state of greater relaxation.
Taken together, there is no doubt that people engaged in yoga lessons regularly are less likely to make the wrong decision under pressure because of the result of yoga in the expression of greater calmness.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Hemisphere-specific EEG related to alternate nostril yoga breathing by Telles S1, Gupta RK2, Yadav A2, Pathak S2, Balkrishna A2. (PubMed)
(2) Yoga breathing through a particular nostril is associated with contralateral event-related potential changes by Telles S1, Joshi M, Somvanshi P.(PubMed)
(3) Effect of Santhi Kriya on certain psychophysiological parameters: a preliminary study by Satyanarayana M1, Rajeswari KR, Rani NJ, Krishna CS, Rao PV. (PubMed)
Yoga may be one of the best practices to induce calmness for people who are in a state of constant pressure, some studies suggested
Yoga, the ancient practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement, and gesture..... has been best known to people in the Western world and some parts in Asia due to health benefits reported by various respectable institutes research and supported by health advocates.
In the study of 13 normal healthy adults to determine the effects of alternate nostril yoga breathing on (a) cerebral hemisphere asymmetry, and (b) changes in the standard EEG bands by assigning the participants into three sessions (a) alternate nostril yoga breathing (ANYB), (b) breath awareness and (c) quiet sitting, on separate days, researchers showed that alternate nostril yoga breathing (ANYB) expressed a higher result in induced calmness through stress and anxiety reduction.
Yoga alternate nostril breathing exercises demonstrated a significant effect on an individual's calmness under certain pressure, probably a result in the settle the mind and body, and emotions and decreased expression of an overactive or worrying mind.
Interestingly, certain posts in the sequence culminating in Padmasana(Lotus Pose) have been found to achieve a calm mind stage, according to the yoga journal.
Other researchers suggested that yoga's inner demonstration of calmness may also have a profound effect on the healing process of the whole person--mind, body, and spirit.
Dr. Ott MJ at the Dana Farber Cancer Institute, said, "Formal and informal daily practice fosters the development of profound inner calmness and nonreactivity of the mind, allowing individuals to face, and even embrace, all aspects of daily life, regardless of circumstances".
Indeed, yoga found the inner peace of participants through intimacy and the ability to listen to the body even in sadness, grief, and other festering emotions.
More importantly, in a study of 8 healthy male volunteers of the age group 25.9 +/- 3 (SD) years assigned to Santhi Kriya practice daily for 50 minutes for 30 days with the volunteer's body weight, blood pressure, oral temperature, pulse rate, respiration, ECG and EEG were recorded before and after the practice on the 1st day and subsequently on 10th, 20th and 30th day of their practice, researchers at the end of the experiment postulated that there was a gradual and significant decrease in the body weight and an increase in alpha activity of the brain (P less than 0.001) during the course of 30 days.
Further analysis also suggested that the increase of alpha activity both in the occipital and prefrontal areas of both the hemispheres of the brain indicated an increase in calmness.
More importantly, Santhi Kriya practice expressed an increase in oral temperature by 3 degrees F and a decreases respiratory rate significantly on all practice days.
Santhi Kriya yoga is a mixture of combined yogic practices of breathing and relaxation.
According to Dr. Richard P. Brown, Patricia L. Gerbarg, and Philip R. Muskin in the book of
How to Use Herbs, Nutrients, & Yoga in Mental Health, Santhi Kriya total cortical alpha activity in the brain is associated with relaxation calmness, and awareness, and the practice may be considered as an adjunct therapy to induce a state of greater relaxation.
Taken together, there is no doubt that people engaged in yoga lessons regularly are less likely to make the wrong decision under pressure because of the result of yoga in the expression of greater calmness.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Hemisphere-specific EEG related to alternate nostril yoga breathing by Telles S1, Gupta RK2, Yadav A2, Pathak S2, Balkrishna A2. (PubMed)
(2) Yoga breathing through a particular nostril is associated with contralateral event-related potential changes by Telles S1, Joshi M, Somvanshi P.(PubMed)
(3) Effect of Santhi Kriya on certain psychophysiological parameters: a preliminary study by Satyanarayana M1, Rajeswari KR, Rani NJ, Krishna CS, Rao PV. (PubMed)
#RegularWalking Reduces the Risk of Low Back LB Disability Onset, Researchers Find
Kyle J. Norton
Chronic back pain is a significant problem worldwide. According to statistics, Low back pain is a Musculoskeletal disorder (MSD, affecting over 80% of the population in the US alone at some point in their life. Chronic LBP (pain has persisted for longer than 3 months(5) prevalence in older adults was significantly higher than in the 21-to-44-year age group.
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contributes to health benefits of low back pain in the younger and older elderly have been lacking, probably due to body height and weight and other parameters(1), such as psychosocial factors(4).
In fact, in a systematic review of studies using pedometers, Dr. Mansi S and colleagues at the University of Otago said, ".....strong evidence for the effectiveness of pedometer walking interventions in increasing PA levels for patients with MSDs", using 11 electronic databases up to 20 February 2014(7).
In support of the effect of exercise, including walking the VA Ann Arbor Healthcare System insisted that exercise is an integral part of managing chronic back pain but to be effective requires that patients actively participate in the management process(6).
Does regular walking reduce the risk of low back pain? the Cooper River Bridge Run Study said, "runners and walkers may have a lower relative risk for significant LBP" and " Prevalence of LBP at the time of survey completion was 13.6%"(9)in this population in comparison to the general statistic.
Indeed, walking 4 to 7 days per week is Vound to reduce the risk of LB disability onset by 50% to 80% in older Black adults and 50% in older White adults(8), respectively.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Physical activity and low-back pain in schoolchildren by Skoffer B1, Foldspang A.(PubMed)
(2) Which physical activities and sports can be recommended to chronic low back pain patients after rehabilitation? by Ribaud A1, Tavares I, Viollet E, Julia M, Hérisson C, Dupeyron A.(PubMed)
(3) Physical activity and low back pain: a systematic review of recent literature by Heneweer H1, Staes F, Aufdemkampe G, van Rijn M, Vanhees L.(PubMed)
(4) Low back pain in schoolchildren: the role of mechanical and psychosocial factors by Watson KD1, Papageorgiou AC, Jones GT, Taylor S, Symmons DP, Silman AJ, Macfarlane GJ.(PubMed)
(5) Management of chronic low back pain by Nikolai Bogduk
(6) Veterans walk to beat back pain: study rationale, design and protocol of a randomized trial of a pedometer-based internet mediated intervention for patients with chronic low back pain by Krein SL1, Metreger T, Kadri R, Hughes M, Kerr EA, Piette JD, Kim HM, Richardson CR.(PubMed)
(7) A systematic review of studies using pedometers as an intervention for musculoskeletal diseases by Mansi S1, Milosavljevic S, Baxter GD, Tumilty S, Hendrick P.(PubMed)
(8) The effect of walking on lower body disability among older blacks and whites by Clark DO1.(PubMed)
(9) The Cooper River Bridge Run Study of low back pain in runners and walkers by Woolf SK1, Barfield WR, Nietert PJ, Mainous AG 3rd, Glaser JA.(PubMed)
Chronic back pain is a significant problem worldwide. According to statistics, Low back pain is a Musculoskeletal disorder (MSD, affecting over 80% of the population in the US alone at some point in their life. Chronic LBP (pain has persisted for longer than 3 months(5) prevalence in older adults was significantly higher than in the 21-to-44-year age group.
Regular physical activity has long been found to associate with the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contributes to health benefits of low back pain in the younger and older elderly have been lacking, probably due to body height and weight and other parameters(1), such as psychosocial factors(4).
Available evidence on the association between physical activity (i.e. occupational load and non-occupational physical activities) and low back pain (LBP)(3).
But according to the review of 2583 initially identified articles, 121 articles analyzed conducted by Fédération hospitals-Universitaire de médecine physique et de réadaptation Montpellier-Nîmes, suggested, " Moderate but regular physical activity(including walking) helps to improve fitness and does not increase the risk of acute pain in chronic LBP patients"(2).
But according to the review of 2583 initially identified articles, 121 articles analyzed conducted by Fédération hospitals-Universitaire de médecine physique et de réadaptation Montpellier-Nîmes, suggested, " Moderate but regular physical activity(including walking) helps to improve fitness and does not increase the risk of acute pain in chronic LBP patients"(2).
In fact, in a systematic review of studies using pedometers, Dr. Mansi S and colleagues at the University of Otago said, ".....strong evidence for the effectiveness of pedometer walking interventions in increasing PA levels for patients with MSDs", using 11 electronic databases up to 20 February 2014(7).
In support of the effect of exercise, including walking the VA Ann Arbor Healthcare System insisted that exercise is an integral part of managing chronic back pain but to be effective requires that patients actively participate in the management process(6).
Does regular walking reduce the risk of low back pain? the Cooper River Bridge Run Study said, "runners and walkers may have a lower relative risk for significant LBP" and " Prevalence of LBP at the time of survey completion was 13.6%"(9)in this population in comparison to the general statistic.
Indeed, walking 4 to 7 days per week is Vound to reduce the risk of LB disability onset by 50% to 80% in older Black adults and 50% in older White adults(8), respectively.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Physical activity and low-back pain in schoolchildren by Skoffer B1, Foldspang A.(PubMed)
(2) Which physical activities and sports can be recommended to chronic low back pain patients after rehabilitation? by Ribaud A1, Tavares I, Viollet E, Julia M, Hérisson C, Dupeyron A.(PubMed)
(3) Physical activity and low back pain: a systematic review of recent literature by Heneweer H1, Staes F, Aufdemkampe G, van Rijn M, Vanhees L.(PubMed)
(4) Low back pain in schoolchildren: the role of mechanical and psychosocial factors by Watson KD1, Papageorgiou AC, Jones GT, Taylor S, Symmons DP, Silman AJ, Macfarlane GJ.(PubMed)
(5) Management of chronic low back pain by Nikolai Bogduk
(6) Veterans walk to beat back pain: study rationale, design and protocol of a randomized trial of a pedometer-based internet mediated intervention for patients with chronic low back pain by Krein SL1, Metreger T, Kadri R, Hughes M, Kerr EA, Piette JD, Kim HM, Richardson CR.(PubMed)
(7) A systematic review of studies using pedometers as an intervention for musculoskeletal diseases by Mansi S1, Milosavljevic S, Baxter GD, Tumilty S, Hendrick P.(PubMed)
(8) The effect of walking on lower body disability among older blacks and whites by Clark DO1.(PubMed)
(9) The Cooper River Bridge Run Study of low back pain in runners and walkers by Woolf SK1, Barfield WR, Nietert PJ, Mainous AG 3rd, Glaser JA.(PubMed)
Combined #Betaxanthins and #Betacyanins with Conventional Anticancer Drugs Reduce Chemo-Drug Toxicity and Overcome the Multidrug Reistance of Cancer Cells
Kyle J. Norton
Chemo-drugs are a class of conventional medicine used for the treatment of cancers. including 5-fluorouracil, 6-mercaptopurine, cytarabine, gemcitabine, and methotrexate.
Compared to other treatments, chemotherapy targets cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival.
Chemo drugs have been found to improve the survival rate of cancer patients. However, they also induce significant side effects.
The most common side effects of chemo-drugs are fatigue, hair loss, easy bruising, and bleeding. infection, anemia (low red blood cell counts) nausea and vomiting, appetite changes, and constipation.
The side effects of chemo drugs are the results of damage to the healthy blood-forming cells in the bone marrow, hair follicles, and cells in the mouth, digestive tract, and reproductive system.
According to the American Cancer Society, some chemo drugs have also been found to damage cells in the heart, kidneys, bladder, lungs, and nervous system.
Therefore, for patients who are at a higher risk of severe symptoms, medicines are taken with the chemo. Sometimes they are a must to help protect your body’s normal cells.
Conventionally, most chemo drugs side effects go away fairly quickly, but some may take months or even years for the symptoms to go away completely.
However, chemo-drugs that cause long-term damage to the heart, lungs, kidneys, or reproductive organs are irreversible.
Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belongings to the group of betalains, found abundantly in beets, chard, etc.
With an aim to find a chemical compound that enhances the chemo drug efficacy and reduces the chemotoxicity, researchers examined the extract of red beetroot (Beta vulgaris L.), the FDA-approved red food color E162, in the development of multi-organ tumors in experimental animals.
By comparing the cytotoxic effect of the red beetroot extract with an anti-cancer drug, doxorubicin (Adriamycin) in the androgen-independent human prostate cancer cells (PC-3) and in the well-established estrogen receptor-positive human breast cancer cells (MCF-7), researchers found that
* Both doxorubicin and the beetroot extract exhibited a dose-dependent cytotoxic effect in both PC-3 and MCF-7 cancer cell lines.
* Doxorubicin, at the concentration of 29 µg/m., completely inhibited the growth of the PC-3 cells in three days.
* Although the cytotoxicity of the beetroot extract was significantly lower compared to doxorubicin, the extract continued to decrease the growth rate of the PC-3 cells (3.7% in 3 days vs. 12.5% in 7 days) at the same concentration.
In other words, both beetroot extract and Doxorubicin exerted a significant cytotoxic activity against the tested cancer cell line. However, the efficacy of beetroot extract is lower compared to those of Doxorubicin.
According to the chemical analysis, betacyanin was found to play an important role in the cytotoxicity exhibited by the red beetroot extract.
Moreover, betaxanthins and betacyanins used in combination with conventional anticancer drugs were found to reduce chemo-drug toxicity and overcome the multidrug resistance of cancer cells.
Based on the finding, researchers concluded betacyanins were used alone or combined with other phytochemicals or chemo drugs to block the onset of the proliferation of tumor cells.
Taken altogether, betacyanins found in beetroot extract were used alone or combined with conventional anti-cancer medicine to enhance the chemo-drugs efficacy and reduce chemotoxicity, pending to the confirmation of the larger sample size and multicenter human study.
Intake of betacyanins in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancercell lines by Kapadia GJ1, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
(2) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES. (PubMed)
Chemo-drugs are a class of conventional medicine used for the treatment of cancers. including 5-fluorouracil, 6-mercaptopurine, cytarabine, gemcitabine, and methotrexate.
Compared to other treatments, chemotherapy targets cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival.
Chemo drugs have been found to improve the survival rate of cancer patients. However, they also induce significant side effects.
The most common side effects of chemo-drugs are fatigue, hair loss, easy bruising, and bleeding. infection, anemia (low red blood cell counts) nausea and vomiting, appetite changes, and constipation.
The side effects of chemo drugs are the results of damage to the healthy blood-forming cells in the bone marrow, hair follicles, and cells in the mouth, digestive tract, and reproductive system.
According to the American Cancer Society, some chemo drugs have also been found to damage cells in the heart, kidneys, bladder, lungs, and nervous system.
Therefore, for patients who are at a higher risk of severe symptoms, medicines are taken with the chemo. Sometimes they are a must to help protect your body’s normal cells.
Conventionally, most chemo drugs side effects go away fairly quickly, but some may take months or even years for the symptoms to go away completely.
However, chemo-drugs that cause long-term damage to the heart, lungs, kidneys, or reproductive organs are irreversible.
Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belongings to the group of betalains, found abundantly in beets, chard, etc.
With an aim to find a chemical compound that enhances the chemo drug efficacy and reduces the chemotoxicity, researchers examined the extract of red beetroot (Beta vulgaris L.), the FDA-approved red food color E162, in the development of multi-organ tumors in experimental animals.
By comparing the cytotoxic effect of the red beetroot extract with an anti-cancer drug, doxorubicin (Adriamycin) in the androgen-independent human prostate cancer cells (PC-3) and in the well-established estrogen receptor-positive human breast cancer cells (MCF-7), researchers found that
* Both doxorubicin and the beetroot extract exhibited a dose-dependent cytotoxic effect in both PC-3 and MCF-7 cancer cell lines.
* Doxorubicin, at the concentration of 29 µg/m., completely inhibited the growth of the PC-3 cells in three days.
* Although the cytotoxicity of the beetroot extract was significantly lower compared to doxorubicin, the extract continued to decrease the growth rate of the PC-3 cells (3.7% in 3 days vs. 12.5% in 7 days) at the same concentration.
In other words, both beetroot extract and Doxorubicin exerted a significant cytotoxic activity against the tested cancer cell line. However, the efficacy of beetroot extract is lower compared to those of Doxorubicin.
According to the chemical analysis, betacyanin was found to play an important role in the cytotoxicity exhibited by the red beetroot extract.
Moreover, betaxanthins and betacyanins used in combination with conventional anticancer drugs were found to reduce chemo-drug toxicity and overcome the multidrug resistance of cancer cells.
Based on the finding, researchers concluded betacyanins were used alone or combined with other phytochemicals or chemo drugs to block the onset of the proliferation of tumor cells.
Taken altogether, betacyanins found in beetroot extract were used alone or combined with conventional anti-cancer medicine to enhance the chemo-drugs efficacy and reduce chemotoxicity, pending to the confirmation of the larger sample size and multicenter human study.
Intake of betacyanins in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancercell lines by Kapadia GJ1, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
(2) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES. (PubMed)
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