#ModeratedCoffee Intake Is Associated with a Reduced Risk of #HeartFailure, According to Studies

By Kyle J. Norton

A renowned university study suggested that intake of coffee and coffee caffeine daily and regularly is associated with a reduced risk of heart failure.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.

In the review literature from the electronic databases (MEDLINE, Embase, and CINAHL) from January 1966 through December 2011, including five independent prospective studies of coffee consumption and heart failure risk, including 6522 heart failure events and 140 220 participants satisfied the standardized protocol, researchers found that coffee consumption displayed a statistically significant J-shaped relationship between coffee and heart failure.


The most effective serving of coffee in reducing the risk of heart failure incidence was 4 servings/day.
but the risk of heart failure increased substantially for people drinking more than 4 cups daily and regularly.

Furthermore, other factors such as sex or by baseline history of myocardial infarction or diabetes showed an insignificant risk of heart failure developing.

Dr. Mostofsky E, the lead author said, "Moderate coffee consumption is inversely associated with risk of heart failure, with the largest inverse association observed for consumption of 4 servings per day".

Additionally, cohorts studies included 59,490 Finnish participants aged 25-74 years, free of HF at baseline, and risk of HF associated with the amount of coffee consumption daily (0, 1-2, 3-4, 5-6, 7-9 and ≥10 cups) were 1.00, 0.9, 0.88, 0.91, 0.96 and 1.02 for men and 1.00, 0.73, 0.77, 0.68, 0.80 and 0.88 for women, respectively.

The result indicated a strong correlation between coffee intake daily and regular in the ameliorated risk of heart failure in women, and coffee consumption was not associated to increase the risk of HF in men. regardless of other independent factors such as age, smoking status, alcohol consumption, history of type 2 diabetes mellitus, and body mass index.

Promisingly, according to the meta-analyses of recent well-controlled prospective epidemiologic studies, conducted by the National University of Singapore and the National University Health System, coffee consumption is associated with a lower risk of heart failure, and for most healthy people, moderate coffee consumption is unlikely to adversely affect cardiovascular health.


Taking all together, Moderated intake of coffee may have a profound effect on the attenuated risk of heart failure, particularly in women, after taking into account other factors.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

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Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Habitual coffee consumption and risk of heart failure: a dose-response meta-analysis by Mostofsky E1, Rice MS, Levitan EB, Mittleman MA.(PubMed)
(2) Coffee consumption and the risk of heart failure in Finnish men and women by Wang Y1, Tuomilehto J, Jousilahti P, Antikainen R, Mähönen M, Männistö S, Katzmarzyk PT, Hu G.(PubMed)
(3) Coffee consumption and cardiovascular health: getting to the Heart of the Matter by Rebello SA1, van Dam RM.(PubMed)

#Herbal #AshwagandhaExtract Inhibits all Parameteras Associated with #Aging Progression, According to Studies

By Kyle J. Norton

Aging is a natural process of getting older. Antiaging is a term that refers to slowing down the aging process. In other words, anti-aging is an action that makes your appearance that looks younger than your biological age, inclduing the use of herbal medicine.

What causes aging? The question that has been asked throughout human history. While many theories try to answer the question by relating aging to the tears and wear of the body, others deal with how the organs and systems in the body develop and deteriorate over time, etc.

The antioxidant theory suggested that the accumulation of damage due to oxidative stress over the long term can initiate DNA oxidation, leading to DNA methylation.

In hormonal theory, the decrease in hormone production gradually found in the human body may contribute to a major cause of aging progression.

In other words, reduced production of hormones affects the amount of hormone released into the bloodstream, leading to decreased functioning of the target organs and systems.

The somatic mutation theory even suggested aging is due to the inherited genes that come directly from the parents. Lifelong exposures to toxins, radiation or ultraviolet light, artificial ingredients, and an unhealthy lifestyle, can increase the risk of cell mutation, leading to incorrect DNA coping.

Some researchers suggested that improved nutrient intake may have a strong effect in delaying the progression of aging and reducing the risk of age-related diseases.

Dr. D. Marsman and colleagues wrote, "New clinical studies of healthy aging are needed and quantitative biomarkers are an essential component, particularly tools which can measure improvements in physiological integrity throughout life, thought to be a primary contributor to a long and productive life (a healthy “lifespan”).


And, "A framework for progress has recently been proposed in a WHO report which takes a broad, person-centered focus on healthy aging, emphasizing the need to better understand an individual’s intrinsic capacity, their functional abilities at various life stages, and the impact by mental, and physical health, and the environments they inhabit.".

The results strongly suggested that if you follow a healthy diet with plenty of nutrients by focusing on calories, and macronutrients, you may delay the process of biological aging.

Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

In finding a potent anti-aging compound, researchers examined the effects of Ashwagandha ( Withania somnifera) in the promotion of youthful vigor, including fatigue, vigor, and steroid hormones in aging men.

The randomized, double-blind, placebo-controlled, crossover study included overweight men aged 40-70 years, with mild fatigue given a placebo or an ashwagandha extract (Shoden beads, delivering 21 mg of withanolide glycosides a day) for 8 weeks.

According to the tested analysis of 50 people completing the first 8-week period of the trial and 43 completing all 16 weeks, the ashwagandha extract-treated group showed improvements in fatigue, vigor, and sexual and psychological well-being.

Furthermore, Ashwagandha intake demonstrated an 18% greater increase in DHEA-S and a 14.7% greater increase in testosterone, compared to the placebo without affecting levels of cortisol and estradiol.

In other words, Ashwagandha increased the levels of male hormones compared to the placebo.

Based on the finding, researchers concluded, " the intake of a standardized ashwagandha extract (Shoden beads) for 8 weeks was associated with increased levels of DHEA-S and testosterone, although no significant between-group differences were found in cortisol, estradiol, fatigue, vigor, or sexual well-being".

Taken altogether, Ashwagandha may be used as an anti-aging functional herb, pending the results from the large sample size and multicenter study

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males by Lopresti AL1,2, Drummond PD1, Smith SJ. (PubMed)
(2) Healthy aging: the natural consequences of good nutrition—a conference report by D. Marsman,1 D. W. Belsky,2 D. Gregori,3 M. A. Johnson,4 T. Low Dog,5 S. Meydani,6S. Pigat,7 R. Sadana,8 A. Shao,9 and J. C. Griffiths. (PMC)

#GreenTea's #EGCG, Inhibits Oxidativestress and Acts as #IronChelator Against the Risk of #Parkinson's disease, Researchers Suggest

By Kye J. Norton


Green tea may be considered as a functional food and iron chelator in reduced risk and progression of Parkinson's disease, some scientists suggested

Iron chelation therapy is a primary and standard treatment for patients with iron overload.

Green tea is a precious drink that processes a number of health benefits known to almost everyone in Asia and the Western world.

Parkinson's disease (PD) is a progressive neurodegenerative disease, that causes severe depletion of glutamatergic and dopaminergic inputs in the striatum.

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Investigation of the green tea EGCG effect in risk and progression of PD has been found to associate to many mechanisms involved in a number of aspects.

Application of metal chelation was found to ameliorate the expression of ROS in the induction of oxidative stress through a chain of reaction and precipitation of aggregation of alpha-synuclein and beta-amyloid peptides deposit in the brain, main leading causes to the onset of PD.

In iron abnormality PD subjects, oxidopamine, also known as 6-hydroxydopamine or 2,4,5-trihydroxyphenethylamine(6-OHD), a neurotoxic synthetic organic compound was found to disrupt iron metabolism, leading to overexpression of the iron induction of dyshomeostasis cause of iron toxicity and oxidative damage in dopaminergic neurons.

Green tea major polyphenol, (−)-epigallocatechin-3-gallate used in metal chelation, ameliorated iron-dependent free radicals located in the subcellular compartments and cellular membranes, through the effect in inhibited iron input and exhibited iron output in brain areas where it preferentially accumulates in neurodegenerative diseases, particularly Parkinsons' disease.

Further analysis of the neurotoxin 6-OHDA causes of iron unstable equilibrium, green extract GECG administration improved the function of hepcidin, a liver-derived hormone in regulated iron dyshomeostasis and gene expression of the iron metabolism through expressions of iron regulatory proteins (IRP1 and IRP2) in regulated the RNA level, between the transcription and the translation of the gene in expression of the iron homeostasis.

Indeed, In the differentiation of neurotoxin 6-OHDA induced iron dyshomeostasis has shown to increase oxidative stress in damage to neuron cells, green extract GECG effects demonstrated a significant inhibition of free radical and iron-free radical expression in the cellular membranes through the antioxidant activities and anti-inflammatory system and expression of nuclear factor-like 2(Nrf2) in stimulated production of antioxidant in protection against oxidative damage during injury and inflammation; heme oxygenase-1(HO-1) in increased production of superoxide dismutase and catalase against ROS and peroxisome proliferator-activated receptor-gamma (PPARγ) in regulated production of pro and anti-inflammatory cytokines and cytokines..

By reducing the overexpression of oxidative damage to neuron cells through regulation of iron-related factors as mentioned above, iron chelator EGCG can counteract these adverse effects and prevent the onset of PD.

Further study of the mechanism on disruption of iron metabolism by 6-OHDA in PD cell line N27, discovered that application of the iron chelator EGCG also disrupts the iron dyshomeostasis in N27 cells (dopaminergic neural cell line) induced by 6-OHDA through regulating iron transporters and regulators expression, such as DMT1 with function in mediation of the entry of dietary iron into these mucosal cells and TfR, a carrier protein for transferrin with function in import iron into the cell and regulated response to intracellular iron concentration and hepcidin, a central regulator in maintain iron homeostasis.

Dysregulation of hepcidin production results in a variety of iron disorders.

Additionally, in 6-OHDA induced neurotoxicity to cause PD, administration of green tea GECG also reduced the intracellular iron retention by decreasing the iron importers and increasing iron exporters, through regulation of the function of iron-regulated transporters, such as ferroportin.

Interestingly, there was a report suggested that the intervention of 3 cups of green tea daily for 3 months improved the antioxidant status and reduced oxidative damage in early PD patients without affecting their iron status.

The findings revealed that green tea bioactive polyphenol, (−)-epigallocatechin-3-gallate may be considered as an iron chelator in the regulation of PD progression.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources

(1) Neuroprotective Properties of the Standardized Extract from Camellia sinensis (Green Tea) and Its Main Bioactive Components, Epicatechin and Epigallocatechin Gallate, in the 6-OHDA Model of Parkinson's Disease by Bitu Pinto N1, da Silva Alexandre B2, Neves KR3, Silva AH3, Leal LK3, Viana GS1.(PubMed)
(2) Green tea polyphenols prevent Parkinson's disease: in vitro and in vivo studies Dan Chen by Iowa State University

#Cranberry Improves #Cardiac Myeloperoxidase (MPO) and Antioxidant Activities Against Cardio-Toxicity and Infection, Researchers say

 By Kyle J. Norton

Cardiac toxicity is a condition in which the heart has been damaged to some extent caused by harmful chemicals, including toxins induced by the treatment of chemotherapy, leading to reduced heart muscle function to pump blood and heart failure.

Long-term intake of certain medications and people who are under treatment of chemotherapy have been found in most cases of cardiotoxicity.

Dr. Polonsky TS, the lead scientist wrote, "Age and preexisting left ventricular dysfunction have been identified most consistently as being associated with the development of clinical heart failure or a worsening of left ventricular function with chemotherapy".

And, "Other cardiovascular conditions, including hypertension, diabetes, and coronary artery disease, are also associated with the risk of cardiotoxicity".

Additionally, human immunodeficiency virus (HIV) infection, genetic preposition, a malignant disease associated with the amyloid deposited on the heart or other organs, high blood pressure, untreated hyperthyroidism, and vitamin b2 deficiency are some of the most prevalent factors found in patients with cardiotoxicity.

Depending on the cells of the areas of the heart that have been damaged, cardiac toxicity includes
* Cardiomyopathy is a disorder that caused a weakening or damage of heart muscle, affecting the heart rhythm or inducing the risk of heart failure.

* Myocarditis is a condition of inflammation of the heart, that can lead to changes in heart rhythm or heart failure.

* Pericarditis is a condition caused by the inflammation of the sac surrounding the heart, inducing chest pain or heart failure.

* Acute coronary syndromes that affect the blood flow due to blood vessel damage.

* Congestive heart failure is a result that affects the function of the heart in pumping blood throughout the body.

The most common symptoms of cardiotoxicity are associated with not enough blood circulation in the body such as tiredness and fatigue, a long-term (chronic) cough, shortness of breath, floating due to the enlarged heart muscle, abnormal heart or lung sounds and swelling in your hands, feet, or unusual weight gain.

Conventionally, treatment of cardiotoxicity is totally depending on the types of the disease including
Beta-blockers, and ACE inhibitors induce (widen) arterial dilation and improvement of blood flow and diuretics.


Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

In finding a potential compound for the treatment of cardiovascular diseases, researchers examined the protective effect of cranberry extract (CRAN) against DOX-induced cardiotoxicity in an animal model.

According to the results of rats being given CRAN orally (100mg/kg/day for 10 consecutive days) and DOX (15mg/kg; i.p.) for 7 days, CRAN protected the heart function against DOX-induced increased mortality and ECG changes.

The reduced levels of antioxidants enzymes and increased oxidative stress in the cardiac tissues induced by DOX such as glutathione (GSH) depletion and oxidized glutathione (GSSG), malondialdehyde (MDA), and protein carbonyls were significantly inhibited by the administration of CRAN.

Furthermore, the reduced cardiac activities of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and glutathione reductase (GR) induced by DOX were also inhibited by CRAN.

Moreover, CRAN also improved the cardiac myeloperoxidase (MPO) activity against infection compared to untreated rats.

Most important, CRAN also normalized the levels of enzymes associated with cardio muscle damage and injury caused by DOX such as troponin I, creatine phosphokinase (CK), and creatine kinase-MB.

Based on the findings, researchers said, "CRAN alleviated histopathological changes in rats' hearts treated with DOX. In conclusion, CRAN protects against DOX-induced cardiotoxicity in rats".

Taken altogether, cranberry may be considered a remedy for the protection of cardiovascular toxicity, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats by Elberry AA1, Abdel-Naim AB, Abdel-Sattar EA, Nagy AA, Mosli HA, Mohamadin AM, Ashour OM. (PubMed)
(2) Risk factors for chemotherapy-related cardiac toxicity by Polonsky TS1, DeCara JM. (PubMed)

#GreenTea's Polyphenols #EGCG) and #Theaflavin (TF) Protect the DNA Damages in the Induction of #LiverCancer, Researchers Show

By Kyle J. Norton

Green tea may have a sustainable and positive effect in reduced risk and treatment of liver cancer, Some studies suggested.

Liver cancer is a medical condition caused by cell growth disorderly and uncontrollably in the liver tissues. At the later stage, the cancerous cells may travel a distance away to infect other healthy organs and tissues.

In the review of medical literature published online, green tea bioactive phytochemicals such as Epigallocatechin gallate (EGCG) and Theaflavin (TF), in the prevention and treatment of liver cancer have been postulated by several mechanisms.

In liver cancer, animal model induced by chronic exposure to N-nitroso diethylamine (NDEA), a carcinogenic and mutagenic organic compound, application of green tea bioactive compounds Epigallocatechin gallate (EGCG) and Theaflavin (TF) demonstrated a strong effect in reduced initiation of cancer formation and potential chemopreventive effect in pre and post-treatment of the injected animal.

Further observation showed that EGCG/TF action in restraining the overexpression of liver cancer was also found to modulate similarly to those of CD44-specific cell membrane binding combined with near-infrared irradiation in the induction of cellular apoptosis.

High CD44-positive expression is found to associate with acute cancer cell killing.

The restriction processes of EGCG/TF in modification of onset of liver cancer development was also found to modify multiple biogenesis involved in maintaining a relatively stable equilibrium in organs tissues(self-renewal Wnt/β-catenin, Hh/Gli1 pathways) in gene with the implication of cell cycle progression, apoptosis and cellular transformation and cell differentiation and proliferation(Cyclin D1, cMyc, and EGFR) and tumor suppressor (E-cadherin) during the carcinogenesis processes.


The additional illustration also indicated that the therapeutic efficacy of tea polyphenols epigallocatechin gallate (EGCG) and theaflavin (TF) also regulated the expression of the protein of cell differentiation, polarity, and proliferation(the self-renewal Wnt and Hedgehog (Hh) pathways).during CCl4/N-nitosodiethylamine-induced mouse liver carcinogenesis.

Application of green tea bioactive tea polyphenols epigallocatechin gallate (EGCG) and theaflavin (TF) induced chemopreventive potential in maintaining cell integrity at the 30 weeks of CCl4/N-nitosodiethylamine application.

Continuous administration of EGCG/TF exerted a strong impact in reduced proliferation and increased apoptosis, as well as the decreased function of hepatic progenitor cells (HPCs) in the participated restoration of the cancerous liver tissue, and population with cancer, stem cell-like characteristics in liver carcinoma observed by AFP and CD44 expression.in CCl4/N-nitosodiethylamine-induced mouse liver carcinogenesis.

More interestingly, also during the restriction processes of EGCG/TF, the bioactive compounds also modulated the expression of tumor progression to a more invasive phenotype(phospho-β-catenin-Y-654), tumor suppressor(β-catenin), the proliferation, migration, and invasion of liver cancer gene(sFRP1 ) and gene in control tumor suppressor(β-catenin).

In other words, green tea EGCG/TF inhibited the contaminated cells inflicted by injection of CCl4/N-nitosodiethylamine to prevent the initiation of liver cancer through modulation of certain gene expressions involved in liver cancer progression.

In short, the inhibition of liver carcinogenesis by EGCG/TF was attributed to a reduction in hepatocyte progenitor cell and stem cell population in restored liver cancerous cell damage through various mechanisms indicated above.

Taken together, green tea bioactive ingredients epigallocatechin gallate (EGCG) and theaflavin (TF) may be useful secondary preventive agents for targeting liver cancer in combination with standard chemotherapies.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice by Sur S1, Pal D2, Roy R2, Barua A2, Roy A3, Saha P2, Panda CK4.(PubMed)
(2) Tea polyphenols epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways by Sur S1, Pal D2, Mandal S3, Roy A4, Panda CK5.(PubMed)

#Yoga Intervention Improves the Lung Functions and Diffusion Capacity in Patients With #CoronaryHeartDisease #(CHD)

By Kyle J. Norton

Yoga may have a profound and positive impact on secondary prevention and improvement on overall conditions in individuals with coronary heart disease, some studies suggested.

Coronary artery disease is a medical condition caused by the accumulation of plaques that block arteries in supplying blood nutrients and oxygen to the heart. Most cases of the disease are associated with atherosclerosis, the condition of hardening of the arteries.

According to statistics, coronary artery disease is the most common type of heart disease that causes the death of over 370,000 people every year, representing 28% of all death in the United States.

Sadly, according to the Centers for Disease Control and Prevention, approximately, 735,000 Americans have a heart attack each year.

What causes plaques to build up on the arterial is debatable. However, researchers suggested that the Western diet is associated with a significantly increased risk of coronary artery disease.

Dr. Venegas-Pino DE in the classification of the effect of diet on heart diseases said," the western-diet-fed male ApoE-/-: Ins2+/Akita mouse, with profound cardiovascular disease involving extensive atherosclerosis, coronary artery disease, and myocardial infarct resulting in shortened lifespan(4)".

Most common symptoms of coronary artery disease are angina, the condition characterized by chest pain or discomfort and shortness of breath as a result of the weakening of heart muscle which can not pump enough blood to the body's needs.

Over time, the prolonged weakened heart muscle can lead to complications of heart failure, irregular heartbeat, or arrhythmia.

Yoga, the ancient practice for harmonized external and internal body well being, through breath control, meditation, bodily movement, and gesture..... has been well known for people in the Western world and some parts of Asia.

In a total of 80 stable CAD patients below 65 years of age of both sexes selected and randomized into two groups of 40 each. yoga Group I for 3 months yoga lessons consisted of yogic postures, pranayama breathing exercises, dietary modification, and holistic teaching along with their conventional medicine while Group II was treated only on conventional medicine after 3 months, researchers found that,

*Groups that attended yoga lessons express statistically significant improvements in slow vital capacity, forced vital capacity, peak expiratory flow rate, maximum voluntary ventilation, and diffusion factor/ transfer factor of the lung for carbon monoxide in comparison to group II.

* The lung function in forced respiratory volume in 1(st) sec (FEV1), and FEV1 % also shows a trend toward improvement although not statistically significant in also compared to the conventional treatment group.

Dr, Yadav A, the lead author after the experiment said, "Yoga regimen was found to improve lung functions and diffusion capacity in CAD patients besides improving cardiovascular functions".

These results suggested that yoga postures and meditation have a profound effect in relaxed arterial muscle to allow more blood to flow through by reduced stress which causes the muscle wall tightening.

Furthermore, yoga posture and breathing techniques also improved the lung muscle in the absorption of more oxygen for the blood.

In support of the above analysis, Dr. Pal A, and colleagues conducted a study of 258 patients from the Department of Cardiology in Chhatrapati Shahuji Maharaj Medical University diagnosed with coronary artery disease randomly divided into 2 groups, the yoga group and the non-yoga group with 129 in each group, yoga attendees after 35-40 min/day, 5 days a week over a period of 18 months displayed a statistically significant reduction in body mass index, waist circumference, systolic and diastolic blood pressure, and heart rate (P < 0.05).

The relaxation to allow more blood to provide nutrients and oxygen to the body's needs may also result in reducing the blood pressure, thus lowering the heart rate.

After taking into account other risk factors, researchers suggested that yoga therapy expressed a significant effect on secondary prevention of mortality and morbidity and health-related quality of life of individuals with coronary heart disease,


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) Effect of yoga regimen on lung functions including diffusion capacity in coronary artery diseasepatients: A randomized controlled study by Yadav A1, Singh S2, Singh K2, Pai P1.(PubMed)
(2) Effect of yogic intervention on the autonomic nervous system in the patients with coronary artery disease: a randomized controlled trial by Pal A, Srivastava N, Narain VS, Agrawal GG, Rani M.(PubMed)
(3) Yoga for secondary prevention of coronary heart disease by Lau HL1, Kwong JS, Yeung F, Chau PH, Woo J.(PubMed)
(4) Evidence of extensive atherosclerosis, coronary artery disease, and myocardial infarction in the ApoE-/-:Ins2+/Akita mouse fed a western diet by Venegas-Pino DE1, Lagrotteria A2, Wang PW3, Morphet J3, Clapdorp C3, Shi Y3, Werstuck GH(PubMed)

Consumption CoffeeCaffeine as Part of a Normal Lifestyle Is Not Associated with FluidLoss, Researchers Suggest

By Kyle J. Norton

Coffee intake may have a diuretic effect in increased urinary secretion, a recent study by a renowned institute suggested
Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.

In an observation study of 10 healthy adults (eight males and two females; age: 27 ± 5 years, weight: 89.5 ± 14.8 kg, height: 1.75 ± 0.08 m, and body mass index: 29.1 ± 4.4 kg m-2) ingested either 200 mL of water (W), or coffee with low caffeine (3 mg kg-1, LCAF), or coffee with high caffeine (6 mg/ kg, HCAF) on three respective separate occasions, researchers found that group injected with high caffeine coffee with (6 mg kgHCAF)demonstrated a greater diuresis during the 3-h period in compared to groups treated with W (356 ± 53 mL) and LCAF.

Furthermore, the volume of urinary secretion of the injection of coffee with high caffeine groups HCAF was 425 mmol compared to groups injected with W of 249 mmol) and LCAF of 177 mmol.

Dr.Seal AD1, the lead author said, "Caffeine intake of 6 mg/kg in the form of coffee can induce an acute diuretic effect, while 3 mg/kg do not disturb the fluid balance in healthy casual coffee-drinking adults at rest".

In contrast to the general belief, coffee consumption does not significantly reduce the fluid balance. According to the University of Birmingham, intake of coffee moderately may have similar hydrating qualities to water, when consumed in moderation.

Additionally, in the review of literature by searching the Medline database of articles published in the medical and scientific literature for the period of January 1966-March 2002, Dr. Maughan RJ, the lead author said, " acute ingestion of caffeine in large doses (at least 250-300 mg, equivalent to the amount found in 2-3 cups of coffee or 5-8 cups of tea) results in a short-term stimulation of urine output in individuals who have been deprived of caffeine for a period of days or weeks".

Interestingly, in a counterbalanced cross-over design, 50 male coffee drinkers (habitually consuming 3-6 cups per day) participated in two trials, each lasting three consecutive days, with controlled physical activity, food, and fluid intake, participants also consumed either 4×200 mL of coffee containing 4 mg/kg caffeine (C) or water (W), researchers filed the following results
1. Intake of coffee during this period showed no significant changes in total body water (TBW) with no differences between trials.
2. Volume urinary secretion showed no difference in the period of examination and between the 2 groups.
3. No change of nude body mass measurement (BM) in the period and between the 2 groups.

Dr. Seal AD, the lead author said, " (there were) no significant differences across a wide range of hematological and urinary markers of hydration status between trials".


The implication of this result insisted that consumption of caffeine-containing beverages as part of a normal lifestyle does not lead to fluid loss in excess of the volume or poor hydration status other than people deprived of caffeine for a period of days or weeks.

Taking tighter, the contradictory results regarded to coffee and coffee caffeine intake in increased urinary volume secretion may require more illustrations from large sample sizes and multi centers studies before the claim can be made either way.

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Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(1) Coffee with High but Not Low Caffeine Content Augments Fluid and Electrolyte Excretion at Rest by Seal AD1, Bardis CN2, Gavrieli A2, Grigorakis P2, Adams JD1, Arnaoutis G2, Yannakoulia M2, Kavouras SA1,3(PubMed)
(2) No evidence of dehydration with moderate daily coffee intake: a counterbalanced cross-over study in a free-living population by Killer SC1, Blannin AK1, Jeukendrup AE1.(PubMed)