By Kyle J. Norton
The immune system formed part of the defense system is the set of cells associated with the activity that protect the body against antigens or infectious agents.
It is one of the body's defense systems against diseases by keeping us healthy and preventing infections.
Immune dysfunction is a chronic condition, depending on the parts of the immune system affected.
Immune dysfunction can be classified into
* The underactive immune system is also known as the weakened immune system. People with an underactive immune system are susceptible to infection, recurrent infections.
* The overactive immune system is also known as autoimmune disease. In this case, patients suffer diseases associated with the immune system that attacks the body tissues.
Immunomodulation is a process in which an immune response is altered to the desired level. In other words, under the immunomodulatory effect, the immune system is responding correctly to the desire of the body, regardless of the type of immune dysfunction.
Some researchers suggested that providing the necessary nutrition which has been found to play major exogenous factor in modulating different aspects of immune function. Therefore, the immune system can be optimal for the benefit of human health.
Dr. the lead scientist outlined,
* " nutrition induces a significant modulation of a marker within the reference range" or
* "nutrition induces a significant modulation of a marker from outside the reference or control range back into the range" or
*"nutrition induces a significant modulation of a marker from within the reference or control range to outside the range" or
* "nutrition prevents a significant modulation of a marker from within the reference or control range to outside the range" or
* "nutrition induces a significant modulation of a marker from a less favorable reference range into the reference range of a comparator group with a more favorable immune function".
Finally, the doctor said, "If related immune function markers show consistent changes, the interpretation will be easy and will follow the same logic as for individual markers" and "If changes in related markers are not consistent, interpretation is greatly helped by good clinical practices that include the a priori definition of the most important ‘lead markers’ (typically groups A and B)".
In other words, immune functioning can be modulated to the body's needs.
The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
With an aim to find a potential compound that processes immunomodulatory effects, researchers examined the onion extract against diseases associated with immune dysfunction.
In vitro, the application of both onion aqueous and ethanolic extract of garlic powder significantly stimulated cell proliferation of rat spleen lymphocytes, by activating a cytokine signaling molecule in the immune system that regulates the activities of white blood cells.
These activities were totally depending on the specific stimulator of cell proliferation. In this case, it was the interleukin 2 (IL2).
In subjects treated with concanavalin, both extracts also modulated the proliferation of rat thymocytes and splenocytes in response to concanavalin administration.
Interestingly, depending on the concentration, onion extracts not only had an inhibitory effect on T cell proliferation at higher concentrations but also increased T cell proliferation at lower concentrations of extracts.
In other words, onion-processed immune modulatory effects depend on the body's needs.
Taken altogether, onion may be considered a remedy for the promotion of immune function, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Garlic and onions: Their cancer prevention properties by Holly L. Nicastro,1 Sharon A. Ross,2 and John A. Milner. (PubMed)
(2) Monitoring immune modulation by nutrition in the general population: identifying and substantiating effects on human health by Ruud Albers, 1 Raphaëlle Bourdet-Sicard, 2 Deborah Braun, 3 Philip C. Calder, 4 Udo Herz, 5Claude Lambert, 6 Irene Lenoir-Wijnkoop, 7 Agnès Méheust, 8 Arthur Ouwehand, 9Phoukham Phothirath, 10 Tomoyuki Sako, 11 Seppo Salminen, 12 André Siemensma, 13Henk van Loveren, 14 and Ulrich Sack. (PMC)
Thursday, 15 June 2023
#Yoga Intervention Alleviate The Symptoms and Disability of #RheumaticDiseases, Researchers Suggest
By Kyle J. Norton
Yoga intervention may have a profound effect to alleviate pain and treat rheumatic diseases, some studies suggested.
Rheumatic diseases are a condition of Musculoskeletal disorders, affecting the joints and muscles.
Yoga, the accident technique practice for harmonized external and internal body well-being, through breath control, meditation, bodily movement, and gesture..... has been best known to people in the Western world and some parts of Asia.
In a study to compare the effect of Tai Chi and yoga therapies in treatments for rheumatologic and musculoskeletal diseases, researchers filed the following report
* Both therapy displays a significant effect of Tai Chi and yoga in the management of rheumatologic diseases, particularly in osteoarthritis of the knee, hip, and hand, and rheumatoid arthritis pain.
* Tai Chi and yoga are safe, expressed a reduction of pain, and improvement of physical function and quality of life in patients with rheumatic diseases.
By the information collected, Uhlig T, the leading author said, "Recommendations for Tai Chi in knee osteoarthritis have recently been issued by the American College of Rheumatology. To allow broader recommendations for the use of Tai Chi and yoga in rheumatic diseases".
The study from McGill University, Montreal suggested that yoga lessons not only improve stress and anxiety and promote a sense of calmness, general well-being, and quality of life but also reduced inflammatory mediators including C-reactive protein and interleukin-6 in overexpression pain in participants with rheumatic disease.
Truly, regular yoga practice can increase muscle strength and endurance, proprioception, the sense equilibrium, and balance, depending on the notion of force and balance, with emphasis on movement through a full range of motion to increase flexibility and mobility, thus reducing physical symptoms in patients with rheumatic diseases.
Some researchers suggested that regular yoga practice
* can improve stress management and can have a feedback effect on improving chronic pain, by affecting the response to pain, and decreasing the level of perceived suffering.
* can improve the movement of joints, as motion and muscle stretching can decrease the intensity of pain or relieve your pain completely in some patients.
Furthermore, yoga breathing, and medication also were found to reduce chronic pain by calming the nervous system to block responses to pain messages, reducing inflammatory chemicals from communicating with nerves, and increasing the release of natural pain-relieving chemicals called endorphins.
However, in the review of randomized controlled trials (RCTs) by comparing yoga with control interventions in patients with rheumatic diseases by searching databases of Medline/PubMed, Scopus, the Cochrane Library, and IndMED through February 2013, eight RCTs selected met the guideline with a total of 559 subjects with two RCTs with a low risk of bias, researchers found that all studies expressed very low evidence for effects on pain and disability, in patients with rheumatic diseases participated in yoga classes, long and short terms.
Taking all together, yoga practice may have a profound effect to alleviate pain and treat rheumatic diseases, however, larger randomized controlled trials. are necessary to reaffirm these possibilities
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Yoga for rheumatic diseases: a systematic review by Cramer H1, Lauche R, Langhorst J, Dobos G.(PubMed)
(2) Yoga in rheumatic diseases by Bartlett SJ1, Moonaz SH, Mill C, Bernatsky S, Bingham CO 3rd.(PubMed)
(3) Tai Chi and yoga as complementary therapies in rheumatologic conditions by Uhlig T1.(PubMed)
Yoga intervention may have a profound effect to alleviate pain and treat rheumatic diseases, some studies suggested.
Rheumatic diseases are a condition of Musculoskeletal disorders, affecting the joints and muscles.
Yoga, the accident technique practice for harmonized external and internal body well-being, through breath control, meditation, bodily movement, and gesture..... has been best known to people in the Western world and some parts of Asia.
In a study to compare the effect of Tai Chi and yoga therapies in treatments for rheumatologic and musculoskeletal diseases, researchers filed the following report
* Both therapy displays a significant effect of Tai Chi and yoga in the management of rheumatologic diseases, particularly in osteoarthritis of the knee, hip, and hand, and rheumatoid arthritis pain.
* Tai Chi and yoga are safe, expressed a reduction of pain, and improvement of physical function and quality of life in patients with rheumatic diseases.
By the information collected, Uhlig T, the leading author said, "Recommendations for Tai Chi in knee osteoarthritis have recently been issued by the American College of Rheumatology. To allow broader recommendations for the use of Tai Chi and yoga in rheumatic diseases".
The study from McGill University, Montreal suggested that yoga lessons not only improve stress and anxiety and promote a sense of calmness, general well-being, and quality of life but also reduced inflammatory mediators including C-reactive protein and interleukin-6 in overexpression pain in participants with rheumatic disease.
Truly, regular yoga practice can increase muscle strength and endurance, proprioception, the sense equilibrium, and balance, depending on the notion of force and balance, with emphasis on movement through a full range of motion to increase flexibility and mobility, thus reducing physical symptoms in patients with rheumatic diseases.
Some researchers suggested that regular yoga practice
* can improve stress management and can have a feedback effect on improving chronic pain, by affecting the response to pain, and decreasing the level of perceived suffering.
* can improve the movement of joints, as motion and muscle stretching can decrease the intensity of pain or relieve your pain completely in some patients.
Furthermore, yoga breathing, and medication also were found to reduce chronic pain by calming the nervous system to block responses to pain messages, reducing inflammatory chemicals from communicating with nerves, and increasing the release of natural pain-relieving chemicals called endorphins.
However, in the review of randomized controlled trials (RCTs) by comparing yoga with control interventions in patients with rheumatic diseases by searching databases of Medline/PubMed, Scopus, the Cochrane Library, and IndMED through February 2013, eight RCTs selected met the guideline with a total of 559 subjects with two RCTs with a low risk of bias, researchers found that all studies expressed very low evidence for effects on pain and disability, in patients with rheumatic diseases participated in yoga classes, long and short terms.
Taking all together, yoga practice may have a profound effect to alleviate pain and treat rheumatic diseases, however, larger randomized controlled trials. are necessary to reaffirm these possibilities
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Yoga for rheumatic diseases: a systematic review by Cramer H1, Lauche R, Langhorst J, Dobos G.(PubMed)
(2) Yoga in rheumatic diseases by Bartlett SJ1, Moonaz SH, Mill C, Bernatsky S, Bingham CO 3rd.(PubMed)
(3) Tai Chi and yoga as complementary therapies in rheumatologic conditions by Uhlig T1.(PubMed)
#Greentea (-)-Epigallocatechin Gallate (EGCG) +Chitosan (CS) and Aspartic Acid (PAA) Attenuates the Risk of #Atherosclerosis
By Kyle J. Norton
Atherosclerosis is a medical condition characterized by the deposition of plaques of fatty material on the inner walls, causing to hardening of the arterial vessels.
According to statistics, the mortality rate of coronary heart disease was about 60% in 2010, compared to 30% for stroke and heart failure.
In the study to determine the effect of green tea bioactive epigallocatechin-3-gallate (EGCG) in ameliorated Porphyromonas gingivalis -induced atherosclerosis in a murine model, after injection of the extract EGCG, the tested mice than fed high-fat diets and injected with P. gingivalis three times a week for 3 weeks, observation at weeks 15 displayed a significant reduction of atherosclerotic plaques accumulated in the branches of arteries, observed by Oil Red O staining
Further analysis also found that the polyphenol extract decreased infection of atherosclerotic lesion areas in the anatomic dilations of the ascending aorta through decreased expression of C-reactive protein, in regulating the acute phase of infection and monocyte chemoattractant protein-1 (MCP-1/CCL2) chemokines in regulated migration and infiltration of monocytes/macrophages of the immune system in induced production of cytokines to counter foreign substances.
Additional observation, also indicated that green tea bioactive epigallocatechin-3-gallate (EGCG) not also improved LDL/very LDL cholesterol but also ameliorated ROS activity via antioxidant in induced low-density lipoprotein (LDL) oxidation, a leading indicator of plague accumulation.
In-depth differentiation, the efficacy of green tea epigallocatechin-3-gallate (EGCG) in reduced expression of atherosclerosis due to bacterial P. gingivalis was attributed to decrease secreted proteins with functions in stimulated inflammatory effects, such as chemokines (CCL2) involved in immunoregulatory and inflammatory processes, matrix metallopeptidase 9 (MMP-9) in regulated pathological remodeling processes that involve inflammation, ICAM-1 (Intercellular Adhesion Molecule 1) involved inflammation of capillary vessel walls, the mitochondrial chaperonin hsp60 in the induction of inflammation,......
Interestingly, in the process to prevent plague initiation of the development of atherosclerosis through the above implications, green tea epigallocatechin-3-gallate (EGCG) also increased levels of antioxidant defense enzyme (heme oxygenase-1 mRNA) HO-1 mRNA levels in reduced expression of oxidative stress in induction of pathogenic inflammatory diseases.
Intrusively, continued investigation of the effect of epigallocatechin-3-gallate (EGCG) in inhibiting the formation and development of atherosclerosis via its anti-inflammatory capability also found that EGCG restricts the function of IL6 (interleukin 6) in induced overexpression of pro-inflammatory cytokines and Angiotensin (Ang) II functions in stimulated and increased vascular permeability through the production of vascular endothelial cell growth factor CRP in initiated the pro-inflammatory process.
Interleukin 6 is an interleukin with duo functions of pro-inflammatory cytokines and anti-inflammatory cytokines.
Amazingly, the antioxidant activities of EGCG also acted as free radical scavengers to prevent ROS to establish a chain reaction in the induction of inflammatory effect in encouraging lipid accumulation in the inner wall of arteries, the leading cause of atherosclerosis.
ROS are free radicals with the function to mediate many pathophysiological processes, such as growth, migration, apoptosis, and secretion of inflammatory cytokines,
Angiotensin is a hormone with function in regulated vasoconstriction in increased blood pressure.
Application of combined (-)-Epigallocatechin gallate (EGCG) +chitosan (CS) and aspartic acid (PAA). demonstrated a significant effect in reduced risk and treatment of atherosclerosis through ameliorated lipid deposition in tested animals.
Compared to the effects of conventional medicine simvastatin with an approximately successful treatment rate of lipid deposition of 15.6%, injection of (-)-Epigallocatechin gallate (EGCG) +chitosan (CS) and aspartic acid (PAA).exhibited overall treatment rate of 16.9%.
The accounted evidence suggests that EGCG, as a natural substance, may have a substantial and therapeutic effect in attenuating the risk and treatment of atherosclerosis through anti-inflammatory and antioxidative activities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sourcesase
(1) Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis -induced atherosclerosis by Yu Cai Tomoko Kurita-Ochiai Tomomi Hashizume Masafumi Yamamoto(Pathogen and Disease)
https://academic.oup.com/femspd/article/67/1/76/2367414
(2) Improving the effectiveness of (-)-epigallocatechin gallate (EGCG) against rabbit atherosclerosis by EGCG-loaded nanoparticles prepared from chitosan and polyaspartic acid by Hong Z1, Xu Y, Yin JF, Jin J, Jiang Y, Du Q.(PubMed)
(3) Epigallocatechin-3-gallate inhibits interleukin-6- and angiotensin II-induced production of C-reactive protein in vascular smooth muscle cells by NingPeng, Jun-tian Liu Fang. Guo. Rui Li(Science Direct)
Atherosclerosis is a medical condition characterized by the deposition of plaques of fatty material on the inner walls, causing to hardening of the arterial vessels.
According to statistics, the mortality rate of coronary heart disease was about 60% in 2010, compared to 30% for stroke and heart failure.
In the study to determine the effect of green tea bioactive epigallocatechin-3-gallate (EGCG) in ameliorated Porphyromonas gingivalis -induced atherosclerosis in a murine model, after injection of the extract EGCG, the tested mice than fed high-fat diets and injected with P. gingivalis three times a week for 3 weeks, observation at weeks 15 displayed a significant reduction of atherosclerotic plaques accumulated in the branches of arteries, observed by Oil Red O staining
Further analysis also found that the polyphenol extract decreased infection of atherosclerotic lesion areas in the anatomic dilations of the ascending aorta through decreased expression of C-reactive protein, in regulating the acute phase of infection and monocyte chemoattractant protein-1 (MCP-1/CCL2) chemokines in regulated migration and infiltration of monocytes/macrophages of the immune system in induced production of cytokines to counter foreign substances.
Additional observation, also indicated that green tea bioactive epigallocatechin-3-gallate (EGCG) not also improved LDL/very LDL cholesterol but also ameliorated ROS activity via antioxidant in induced low-density lipoprotein (LDL) oxidation, a leading indicator of plague accumulation.
In-depth differentiation, the efficacy of green tea epigallocatechin-3-gallate (EGCG) in reduced expression of atherosclerosis due to bacterial P. gingivalis was attributed to decrease secreted proteins with functions in stimulated inflammatory effects, such as chemokines (CCL2) involved in immunoregulatory and inflammatory processes, matrix metallopeptidase 9 (MMP-9) in regulated pathological remodeling processes that involve inflammation, ICAM-1 (Intercellular Adhesion Molecule 1) involved inflammation of capillary vessel walls, the mitochondrial chaperonin hsp60 in the induction of inflammation,......
Interestingly, in the process to prevent plague initiation of the development of atherosclerosis through the above implications, green tea epigallocatechin-3-gallate (EGCG) also increased levels of antioxidant defense enzyme (heme oxygenase-1 mRNA) HO-1 mRNA levels in reduced expression of oxidative stress in induction of pathogenic inflammatory diseases.
Intrusively, continued investigation of the effect of epigallocatechin-3-gallate (EGCG) in inhibiting the formation and development of atherosclerosis via its anti-inflammatory capability also found that EGCG restricts the function of IL6 (interleukin 6) in induced overexpression of pro-inflammatory cytokines and Angiotensin (Ang) II functions in stimulated and increased vascular permeability through the production of vascular endothelial cell growth factor CRP in initiated the pro-inflammatory process.
Interleukin 6 is an interleukin with duo functions of pro-inflammatory cytokines and anti-inflammatory cytokines.
Amazingly, the antioxidant activities of EGCG also acted as free radical scavengers to prevent ROS to establish a chain reaction in the induction of inflammatory effect in encouraging lipid accumulation in the inner wall of arteries, the leading cause of atherosclerosis.
ROS are free radicals with the function to mediate many pathophysiological processes, such as growth, migration, apoptosis, and secretion of inflammatory cytokines,
Angiotensin is a hormone with function in regulated vasoconstriction in increased blood pressure.
Application of combined (-)-Epigallocatechin gallate (EGCG) +chitosan (CS) and aspartic acid (PAA). demonstrated a significant effect in reduced risk and treatment of atherosclerosis through ameliorated lipid deposition in tested animals.
Compared to the effects of conventional medicine simvastatin with an approximately successful treatment rate of lipid deposition of 15.6%, injection of (-)-Epigallocatechin gallate (EGCG) +chitosan (CS) and aspartic acid (PAA).exhibited overall treatment rate of 16.9%.
The accounted evidence suggests that EGCG, as a natural substance, may have a substantial and therapeutic effect in attenuating the risk and treatment of atherosclerosis through anti-inflammatory and antioxidative activities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sourcesase
(1) Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis -induced atherosclerosis by Yu Cai Tomoko Kurita-Ochiai Tomomi Hashizume Masafumi Yamamoto(Pathogen and Disease)
https://academic.oup.com/femspd/article/67/1/76/2367414
(2) Improving the effectiveness of (-)-epigallocatechin gallate (EGCG) against rabbit atherosclerosis by EGCG-loaded nanoparticles prepared from chitosan and polyaspartic acid by Hong Z1, Xu Y, Yin JF, Jin J, Jiang Y, Du Q.(PubMed)
(3) Epigallocatechin-3-gallate inhibits interleukin-6- and angiotensin II-induced production of C-reactive protein in vascular smooth muscle cells by NingPeng, Jun-tian Liu Fang. Guo. Rui Li(Science Direct)
#Coffee Reduces the Risk of #LiverCirrhosis Through its Antioxidant and phytochemical Activities, Researchers Say
By Kyle J. Norton
Intake of coffee daily and regularly may have a profound and therapeutic effect in reduced risk and treatment of Hepatic
Cirrhosis
Coffee, second to green tea, is a popular and social beverage all over the world, particularly in the West, made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.
Hepatic Cirrhosis is a condition characterized by the abnormal function of the liver due to the presence of live damage or scarring.
In the experiments in cellular and animal models provided biological plausibility, coffee consumption exhibited a liver protective effect in preventing Cirrhosis from developing through its antifibrotic activity.
According to the Arauz and colleagues study in the exam, one of the key questions regarding the anti-fibrotic role of coffee, coffee as a specifically primary antifibrotic agent is considered as a functional food in prevent and treatment of chronic liver disease.
Dr. Dranoff J in the analysis Coffee Consumption and Risk of Cirrhosis suggested that coffee consumption is inversely related to the progression of liver fibrosis to cirrhosis and even hepatocellular carcinoma.
Furthermore, in the study to evaluate the hepatoprotective properties of coffee and caffeine in a model of chronic bile duct ligation (BDL) in male Wistar rats with liver injury induced by 28-day BDL, assigned to the administered group of conventional coffee, decaffeinated coffee, or caffeine daily, researchers at the lead Autonomous University of Baja California, filed the following results
1. Intake of coffee showed significant effects in promoting the antioxidant status by restoring the redox equilibrium, preventing the elevation of liver enzymes as well as hepatic glycogen depletion.
2. Coffee and caffeine consumption prevented collagen increases
3. Coffee intake reduced protein expression in promoting hepatic infectious cell activation,
4. Coffee intake decreased expression levels of transforming growth factor-β, connective tissue growth factor, α-smooth muscle actin, and collagen in inducing further damage in a tested model of chronic bile duct ligation (BDL).
The result indicated that coffee intake have a strong efficacy in prevent liver cirrhosis development through antioxidant activity, hepaprotective effect, reduced profibrotic molecules, and proinflammation-involved expression of Cirrhosis.
More interestingly, in the comparison of the total of 195 patients with end-stage liver disease (ESLD) consumed coffee on a daily basis and 184 patients did not. researchers at the joint study led by the University Hospital of Heidelberg found that coffee consumption, in fact, ameliorated the progression of liver cirrhosis and increased long-term survival after liver transplantation compared to nondrinker.
With all the information found, one may be considered coffee as a functional food in attenuated risk and treatment of liver cirrhosis through its liver protective effect via phytochemicals in demonstration of antioxidant expression.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Coffee Consumption and Prevention of Cirrhosis - In Support of the Caffeine Hypothesis by Dranoff J1.(PubMed)
(2) Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans by Arauz J1, Zarco N2, Hernández-Aquino E3, Galicia-Moreno M1, Favari L3, Segovia J2, Muriel P4.(PubMed)
#Healthyfood #NavyBean, Lentils and Chickpeas Normalize the Postprandial Glycemic Response, Researchers Say
By Kyle J. Norton
Diabetes is a chronic disease associated with insufficient insulin entering the bloodstream to regulate the glucose caused by either the cells in the pancreas died-off or receptor sites clogged up by fat and cholesterol. Hyperglycemia is a condition of abnormally high levels of glucose in the bloodstream.
Glycemic response is a change in blood glucose after consuming a carbohydrate-containing food compared to Glycemic Index (GI) which ranks carbohydrate-containing foods according to their effect on blood glucose levels.
In other words, the glycemic response is the change of blood glucose after the intake of a food or meal.
Postprandial blood glucose is the level taken after 2 hours of a meal, generally at the approximate peak value in patients with diabetes.
According to the 2015 statistics by the American Diabetes Association, in the U.S. over 30.3 million Americans, or 9.4% of the population are living with diabetes. Sadly, out of 30.3 million adults with diabetes, 23.1 million were diagnosed, and 7.2 million were undiagnosed.
Believe it or not, in 2015, 84.1 million Americans age 18 and older had prediabetes.
Most people who are not prediabetes or diabetes have normal blood glucose and insulin levels that rise within the range after eating, then return to the fasting levels over a short period of time.
According to epidemiological studies, by controlling the glycaemic response within the healthy range, the glycaemic response can reduce the risk of type 2 diabetes. Some researchers suggested including additional fibers into a meal or food can reduce the levels of glucose shortly after intake.
By managing postprandial blood glucose effectively, diabetics can decrease the risk of microvascular (retinopathy, nephropathy, and neuropathy) and cardiovascular disease (CVD).
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a potential compound for the improvement of postprandial glycaemic response, researchers examined the effect of dietary intake of pulses, including navy bean.
The study included healthy young men who received commercially prepared pulse powders and BG response was recorded before and after a subsequent meal.
More precisely, participants were randomly divided into a whole, puréed, and powdered pulses (navy beans in Expt 1; lentils in Expt 2; chickpeas in Expt 3) and whole-wheat flour as the control.
After a fixed-energy pizza meal (50·2 kJ/kg body weight) was provided at 120 min, the BG concentration was measured before (0-120 min) and after (140-200 min) the pizza meal, researchers found that
* Compared with the whole-wheat flour control, navy bean treatments lowered peak BG concentrations but not the mean BG concentration over 120 min.
* Compared to nay bean, all lentils and chickpeas lower the mean BG concentration over 120 min after treatments
* Moreover, processing pulses to powdered form does not eliminate the benefits of whole pulses on BG response.
Based on the finding, researchers said, "the use of pulse powders as value-added food ingredients to moderate postprandial glycaemic response".
Taken altogether, Navy bean used alone or combined with conventional medicine may be considered a remedy for the improvement of postprandial glycaemic response, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The acute effect of commercially available pulse powders on postprandial glycaemic response in healthy young men by Anderson GH1, Liu Y1, Smith CE1, Liu TT1, Nunez MF1, Mollard RC1, Luhovyy BL. (PubMed)
(2) First and second meal effects of pulses on blood glucose, appetite, and food intake at a later meal by Mollard RC1, Wong CL, Luhovyy BL, Anderson GH. (PubMed)
Diabetes is a chronic disease associated with insufficient insulin entering the bloodstream to regulate the glucose caused by either the cells in the pancreas died-off or receptor sites clogged up by fat and cholesterol. Hyperglycemia is a condition of abnormally high levels of glucose in the bloodstream.
Glycemic response is a change in blood glucose after consuming a carbohydrate-containing food compared to Glycemic Index (GI) which ranks carbohydrate-containing foods according to their effect on blood glucose levels.
In other words, the glycemic response is the change of blood glucose after the intake of a food or meal.
Postprandial blood glucose is the level taken after 2 hours of a meal, generally at the approximate peak value in patients with diabetes.
According to the 2015 statistics by the American Diabetes Association, in the U.S. over 30.3 million Americans, or 9.4% of the population are living with diabetes. Sadly, out of 30.3 million adults with diabetes, 23.1 million were diagnosed, and 7.2 million were undiagnosed.
Believe it or not, in 2015, 84.1 million Americans age 18 and older had prediabetes.
Most people who are not prediabetes or diabetes have normal blood glucose and insulin levels that rise within the range after eating, then return to the fasting levels over a short period of time.
According to epidemiological studies, by controlling the glycaemic response within the healthy range, the glycaemic response can reduce the risk of type 2 diabetes. Some researchers suggested including additional fibers into a meal or food can reduce the levels of glucose shortly after intake.
By managing postprandial blood glucose effectively, diabetics can decrease the risk of microvascular (retinopathy, nephropathy, and neuropathy) and cardiovascular disease (CVD).
The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to its numerous health benefits.
With an aim to find a potential compound for the improvement of postprandial glycaemic response, researchers examined the effect of dietary intake of pulses, including navy bean.
The study included healthy young men who received commercially prepared pulse powders and BG response was recorded before and after a subsequent meal.
More precisely, participants were randomly divided into a whole, puréed, and powdered pulses (navy beans in Expt 1; lentils in Expt 2; chickpeas in Expt 3) and whole-wheat flour as the control.
After a fixed-energy pizza meal (50·2 kJ/kg body weight) was provided at 120 min, the BG concentration was measured before (0-120 min) and after (140-200 min) the pizza meal, researchers found that
* Compared with the whole-wheat flour control, navy bean treatments lowered peak BG concentrations but not the mean BG concentration over 120 min.
* Compared to nay bean, all lentils and chickpeas lower the mean BG concentration over 120 min after treatments
* Moreover, processing pulses to powdered form does not eliminate the benefits of whole pulses on BG response.
Based on the finding, researchers said, "the use of pulse powders as value-added food ingredients to moderate postprandial glycaemic response".
Taken altogether, Navy bean used alone or combined with conventional medicine may be considered a remedy for the improvement of postprandial glycaemic response, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The acute effect of commercially available pulse powders on postprandial glycaemic response in healthy young men by Anderson GH1, Liu Y1, Smith CE1, Liu TT1, Nunez MF1, Mollard RC1, Luhovyy BL. (PubMed)
(2) First and second meal effects of pulses on blood glucose, appetite, and food intake at a later meal by Mollard RC1, Wong CL, Luhovyy BL, Anderson GH. (PubMed)
#Antioxidant #Betacyanins Process A Significant #FreeRadicalScavengering Activities, Researchers Show
By Kyle J. Norton
Free radical scavengers are antioxidants that gobble up free radicals before they can cause a chain of reaction.
The most common types of free radical scavengers are catalase, glutathione peroxidase, superoxide dismutase (SOD), and vitamins A, C, D, and E.
Free radicals are highly unstable molecules. They can be everywhere. Internally, free radicals are produced in our bodies during the process of cell metabolism. Externally, free radicals can enter our bodies from environmental sources, such as the air we breathe, the food we eat, and the water we drink.
In other words, any chemical compounds or molecules which process oxygen atoms can be free radicals after chemical interaction.
Oxidative stress is a result of overexpression of free radical-induced by a chain reaction that can not be stopped due to reduced levels of antioxidant enzymes produced by the body.
Why? overexpression of free radicals causes lipid peroxidation by oxidizing the free and ester forms of unsaturated fatty acids and cholesterol through three distinct mechanisms, including free radical-mediated chain reaction, enzyme-mediated oxidation, and nonradical, nonenzymatic oxidation.
Over time, oxidative stress can damage the lipid, and protein and induce the alternation of healthy cell DNA.
How important are free radical scavengers to our bodies? Dr. Milind S Hatwalne in the investigation of the effect of free radical scavengers in anesthesiology and critical care wrote, "Free radicals are highly reactive and unstable compounds. They play a central role in the mechanism of cell injury and cell death".
And, "Free radical scavengers either prevent these reactive species from being formed or remove them before they can damage vital components of the cell" and "Several clinical trials have been performed in order to reduce oxidative stress by supplementation of antioxidants alone or in combination with standard therapies. Antioxidant supplementation at an early stage of illness may lead to improved therapies in the treatment of critically ill patients".
In other words, antioxidants with free radical scavenging activity may protect the body against damage to various cellular components.
Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to find a potential compound for the treatment of diseases associated with oxidative stress, researchers examined the effect of betacyanins as free radical scavengers.
By analyzing the compound in betacyanins, researchers found that
* Betanin was a weak free radical scavenger in the free radical chain-breaking probably due to kinetic solvent effects on its solubility, stability, and reaction rates, and partition in lipid bilayers (a thin polar membrane) activity.
* Betanidin also found in betacyanins behaved as a chain-terminating antioxidant in the liposomal model,.particualrly in peroxyl radical-scavenging activity
The finding strongly suggested that betacyanins exhibit a chemical reaction of betanin and its glycone betanidin towards peroxyl radicals generated from the azo-initiated oxidation.
Additionally, in the peroxyl radical generating system with the presence of AAPH and NO-generating system, researchers assessed the antioxidant capacity of betacyanins as indole-derived plant pigments, such as betanin, phyllotactic, and betanidin.
According to the tested assays, betacyanins induced peroxyl radical scavenging capacity at a dose-dependent in the low concentration range (25-100 nM).
Furthermore, betacyanins also reduced the nitrite level in the low concentration range of 2.5-20 μM.
In chemical ingredients differentiation, the IC₅₀ values (μM) of nitrogen radical scavenging activity were 24.48, 17.51, and 6.81 for betanin, phyllocactin, and betanidin.
Based on the results, Dr. Taira J, the lead scientist wrote, "These results indicated that betacyanins have a strong antioxidant capacity, particularly betanidin with a catechol group had higher activity than those of the glycoside of betacyanins".
Taken altogether, betacyanins may be considered free radical scavengers to terminate the oxidative reaction, pending the confirmation of the larger sample size and multicenter human study.
Intake of betacyanins in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betacyanins as phenol antioxidants. Chemistry and mechanistic aspects of the lipoperoxyl radical-scavenging activity in solution and liposomes by Tesoriere L1, Allegra M, Gentile C, Livrea MA. (PubMed)
(2) Antioxidant capacity of betacyanins as radical scavengers for peroxyl radical and nitric oxide by Taira J1, Tsuchida E2, Katoh MC2, Uehara M2, Ogi T. (PubMed)
(3) Free radical scavengers in anesthesiology and critical care by Milind S Hatwalne. (PMC)
Free radical scavengers are antioxidants that gobble up free radicals before they can cause a chain of reaction.
The most common types of free radical scavengers are catalase, glutathione peroxidase, superoxide dismutase (SOD), and vitamins A, C, D, and E.
Free radicals are highly unstable molecules. They can be everywhere. Internally, free radicals are produced in our bodies during the process of cell metabolism. Externally, free radicals can enter our bodies from environmental sources, such as the air we breathe, the food we eat, and the water we drink.
In other words, any chemical compounds or molecules which process oxygen atoms can be free radicals after chemical interaction.
Oxidative stress is a result of overexpression of free radical-induced by a chain reaction that can not be stopped due to reduced levels of antioxidant enzymes produced by the body.
Why? overexpression of free radicals causes lipid peroxidation by oxidizing the free and ester forms of unsaturated fatty acids and cholesterol through three distinct mechanisms, including free radical-mediated chain reaction, enzyme-mediated oxidation, and nonradical, nonenzymatic oxidation.
Over time, oxidative stress can damage the lipid, and protein and induce the alternation of healthy cell DNA.
How important are free radical scavengers to our bodies? Dr. Milind S Hatwalne in the investigation of the effect of free radical scavengers in anesthesiology and critical care wrote, "Free radicals are highly reactive and unstable compounds. They play a central role in the mechanism of cell injury and cell death".
And, "Free radical scavengers either prevent these reactive species from being formed or remove them before they can damage vital components of the cell" and "Several clinical trials have been performed in order to reduce oxidative stress by supplementation of antioxidants alone or in combination with standard therapies. Antioxidant supplementation at an early stage of illness may lead to improved therapies in the treatment of critically ill patients".
In other words, antioxidants with free radical scavenging activity may protect the body against damage to various cellular components.
Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to find a potential compound for the treatment of diseases associated with oxidative stress, researchers examined the effect of betacyanins as free radical scavengers.
By analyzing the compound in betacyanins, researchers found that
* Betanin was a weak free radical scavenger in the free radical chain-breaking probably due to kinetic solvent effects on its solubility, stability, and reaction rates, and partition in lipid bilayers (a thin polar membrane) activity.
* Betanidin also found in betacyanins behaved as a chain-terminating antioxidant in the liposomal model,.particualrly in peroxyl radical-scavenging activity
The finding strongly suggested that betacyanins exhibit a chemical reaction of betanin and its glycone betanidin towards peroxyl radicals generated from the azo-initiated oxidation.
Additionally, in the peroxyl radical generating system with the presence of AAPH and NO-generating system, researchers assessed the antioxidant capacity of betacyanins as indole-derived plant pigments, such as betanin, phyllotactic, and betanidin.
According to the tested assays, betacyanins induced peroxyl radical scavenging capacity at a dose-dependent in the low concentration range (25-100 nM).
Furthermore, betacyanins also reduced the nitrite level in the low concentration range of 2.5-20 μM.
In chemical ingredients differentiation, the IC₅₀ values (μM) of nitrogen radical scavenging activity were 24.48, 17.51, and 6.81 for betanin, phyllocactin, and betanidin.
Based on the results, Dr. Taira J, the lead scientist wrote, "These results indicated that betacyanins have a strong antioxidant capacity, particularly betanidin with a catechol group had higher activity than those of the glycoside of betacyanins".
Taken altogether, betacyanins may be considered free radical scavengers to terminate the oxidative reaction, pending the confirmation of the larger sample size and multicenter human study.
Intake of betacyanins in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betacyanins as phenol antioxidants. Chemistry and mechanistic aspects of the lipoperoxyl radical-scavenging activity in solution and liposomes by Tesoriere L1, Allegra M, Gentile C, Livrea MA. (PubMed)
(2) Antioxidant capacity of betacyanins as radical scavengers for peroxyl radical and nitric oxide by Taira J1, Tsuchida E2, Katoh MC2, Uehara M2, Ogi T. (PubMed)
(3) Free radical scavengers in anesthesiology and critical care by Milind S Hatwalne. (PMC)
#Coffee Promotes Vascular Function in Reducing the Risk of Cardiovascular Diseases, According to Studies
By Kyle J. Norton
Coffee may have a profound effect on the stimulated function of arteries and veins to provide nutrients and fluids to the body through blood and water circulation, a joint study suggested.
Vascular function is the action of arteries and veins, involving blood and water circulation in the body.
Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.
According to the study led by the University of Reading, chlorogenic acids isolated from the coffee roasted bean, acutely improved vascular function, partly acting as mediators mediated by 5-CQA in regulating the normal function of arteries and veins.
In an acute randomized, controlled, cross-over human intervention trial conducted to examine the impact of coffee intake, matched for caffeine but differing in CGA content (89, and 310 mg) on flow-mediated dilatation (FMD) in 15 healthy male subjects, in compared a second intervention trial conducted with 24 healthy male subjects, the impact of pure 5-caffeoylquinic acid (5-CQA), the main CGA in coffee(5-CQA; 450 mg and 900 mg) on FMD, researchers filed the following results
1. Low and high CGA(89 mg and 310 mg CGA) intake, showed a significant effect on vascular function 1 hour after injecting coffee
2. Coffee intake was found closely associated with the paralleled to the appearance of CGA metabolites in regulating the normal function of arteries and veins at 5 hours
3. 5-CQA (450 mg) expressed an improvement by FMD assay after i hour of administration.
The information findings suggested that coffee has a strong effect on activated vascular function through its phytochemicals, including CGA and its metabolites in plasma, 3-, 4- and 5-feruloyl quinic acid and ferulic-4'-O-sulfate at 1 h and isoferulic-3'-O-glucuronide and ferulic-4'-O-sulfate.
Other, A total of 38 men and 37 women with a mean ± SD age of 38.5 and body mass index of 24.1 were randomly assigned to 3 groups: a control group that did not consume coffee or a placebo and 2 groups that consumed 400 mL coffee/d for 8 wk containing a medium (MCCGA; 420 mg) or high (HCCGA; 780 mg) CGA content, researchers filed the results as follow
1. Coffee consumption over the period indicated and after 1 hour showed a significant presence of caffeic and ferulic acid concentrations in the coffee-drinking groups, with different values in the 2 coffee injection groups.
2. At the same time as in 1, the levels of antioxidant expression increased substantially in 2 coffee intake groups but were undetectable in the control group or placebo.
3. All amounts of antioxidants and phytochemicals creased to exist after 8 weeks.
The evidence in the study demonstrated an acute effect of coffee in promoting vascular function in improved nutrients and fluid transportation by arteries and vessels.
Dr. Agudelo-Ochoa GM, the lead author said, "Both coffees, which contained CGAs and were low in diterpenes and caffeine, provided bioavailable CGAs and had a positive acute effect on the plasma AC in healthy adults and no effect on blood lipids or vascular function" and "The group that did not drink coffee showed no improvement in serum lipid profile, FMD, BP, or NO plasma metabolites".
Taking together, there is no doubt that coffee consumption has an enormous effect o improved vascular function in reduced risk of cardiovascular incidence and complications.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: Two randomized, controlled, crossover intervention trials by Mills CE1, Flury A2, Marmet C3, Poquet L3, Rimoldi SF2, Sartori C4, Rexhaj E2, Brenner R2, Allemann Y2, Zimmermann D3, Gibson GR1, Mottram DS1, Oruna-Concha MJ1, Actis-Goretta L3, Spencer JP5.(PubMed)
(2) Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial by Agudelo-Ochoa GM1, Pulgarín-Zapata IC2, Velásquez-Rodriguez CM3, Duque-Ramírez M4, Naranjo-Cano M5, Quintero-Ortiz MM5, Lara-Guzmán OJ6, Muñoz-Durango K2. (PubMed)
Coffee may have a profound effect on the stimulated function of arteries and veins to provide nutrients and fluids to the body through blood and water circulation, a joint study suggested.
Vascular function is the action of arteries and veins, involving blood and water circulation in the body.
Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.
According to the study led by the University of Reading, chlorogenic acids isolated from the coffee roasted bean, acutely improved vascular function, partly acting as mediators mediated by 5-CQA in regulating the normal function of arteries and veins.
In an acute randomized, controlled, cross-over human intervention trial conducted to examine the impact of coffee intake, matched for caffeine but differing in CGA content (89, and 310 mg) on flow-mediated dilatation (FMD) in 15 healthy male subjects, in compared a second intervention trial conducted with 24 healthy male subjects, the impact of pure 5-caffeoylquinic acid (5-CQA), the main CGA in coffee(5-CQA; 450 mg and 900 mg) on FMD, researchers filed the following results
1. Low and high CGA(89 mg and 310 mg CGA) intake, showed a significant effect on vascular function 1 hour after injecting coffee
2. Coffee intake was found closely associated with the paralleled to the appearance of CGA metabolites in regulating the normal function of arteries and veins at 5 hours
3. 5-CQA (450 mg) expressed an improvement by FMD assay after i hour of administration.
The information findings suggested that coffee has a strong effect on activated vascular function through its phytochemicals, including CGA and its metabolites in plasma, 3-, 4- and 5-feruloyl quinic acid and ferulic-4'-O-sulfate at 1 h and isoferulic-3'-O-glucuronide and ferulic-4'-O-sulfate.
Other, A total of 38 men and 37 women with a mean ± SD age of 38.5 and body mass index of 24.1 were randomly assigned to 3 groups: a control group that did not consume coffee or a placebo and 2 groups that consumed 400 mL coffee/d for 8 wk containing a medium (MCCGA; 420 mg) or high (HCCGA; 780 mg) CGA content, researchers filed the results as follow
1. Coffee consumption over the period indicated and after 1 hour showed a significant presence of caffeic and ferulic acid concentrations in the coffee-drinking groups, with different values in the 2 coffee injection groups.
2. At the same time as in 1, the levels of antioxidant expression increased substantially in 2 coffee intake groups but were undetectable in the control group or placebo.
3. All amounts of antioxidants and phytochemicals creased to exist after 8 weeks.
The evidence in the study demonstrated an acute effect of coffee in promoting vascular function in improved nutrients and fluid transportation by arteries and vessels.
Dr. Agudelo-Ochoa GM, the lead author said, "Both coffees, which contained CGAs and were low in diterpenes and caffeine, provided bioavailable CGAs and had a positive acute effect on the plasma AC in healthy adults and no effect on blood lipids or vascular function" and "The group that did not drink coffee showed no improvement in serum lipid profile, FMD, BP, or NO plasma metabolites".
Taking together, there is no doubt that coffee consumption has an enormous effect o improved vascular function in reduced risk of cardiovascular incidence and complications.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: Two randomized, controlled, crossover intervention trials by Mills CE1, Flury A2, Marmet C3, Poquet L3, Rimoldi SF2, Sartori C4, Rexhaj E2, Brenner R2, Allemann Y2, Zimmermann D3, Gibson GR1, Mottram DS1, Oruna-Concha MJ1, Actis-Goretta L3, Spencer JP5.(PubMed)
(2) Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial by Agudelo-Ochoa GM1, Pulgarín-Zapata IC2, Velásquez-Rodriguez CM3, Duque-Ramírez M4, Naranjo-Cano M5, Quintero-Ortiz MM5, Lara-Guzmán OJ6, Muñoz-Durango K2. (PubMed)
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