#Mustards Reduce the Risk of Chronic Diseases Through Their Antioxidants and Anti-Chemical Toxicity Activity, Researchers Say

By Kyle J. Norton

Chronic diseases are a group of medical conditions most commonly associated with aging, including arthritis, cardiovascular diseases such as heart attacks and stroke, cancer, diabetes, epilepsy and seizures, and obesity.

Nutrigenomic activity is a scientific term that optimizes the interaction of nutrition and genes, especially in the prevention or treatment of disease.

In other words, the nutrigenomic activity provided information on how the interaction of certain foods with specific genes leads to the increased risk of chronic diseases such as type 2 diabetes, obesity, heart disease, stroke, and certain cancers.

Biologically, nutrigenomics also provided information molecularly how chemicals found in the diet altered the expression of genes that affect individual health.

More precisely, nutrigenomics is depending totally on an individual's genetic makeup.

According to the Centers for Disease Control, chronic diseases also are the major driver of healthcare costs, accounting for nearly 75 percent of aggregate healthcare spending and increasing absenteeism that impact workforce patterns.

Each chronic patient has cost health care spending $5300 annually.

Believe it or not, chronic diseases in the US, chronic diseases are responsible for 7 out of 10 deaths yearly. In other words, chronic diseases kill more than 1.7 million Americans each year.

According to the joint study led by Fordham University, chronic diseases are among the most prevalent and costly health conditions in the US, affecting over 133 million of the US population as many of them suffer from at least one chronic disease and the number is growing at a rapid rate.

Some chronic diseases such as cancer have been found to be the leading causes of hospitalization, long-term disability, reduced quality of life, and death.

The World Health Organization suggested that unhealthy diet and excessive energy intake, physical inactivity, and tobacco use are some of the most common causes of chronic diseases.

In other words, an unhealthy diet and physical inactivity raised blood pressure, raised glucose levels, abnormal blood lipids (particularly low-density lipoprotein – LDL cholesterol), and overweight (body mass index ≥25 kg/m2) and obesity (body mass index ≥30 kg/m2) are some of the most common prevalent factors found in patients in the Western World.

Other risk factors associated with the risk of chronic disease also inclduing excessive alcohol drinking, infectious agents, and some environmental factors such as air pollution, which contribute to asthma and other chronic respiratory diseases.

Some researchers suggested by changing unhealthy lifestyle patterns, chronic diseases may be preventable.

Dr. Walter C. Willett, the lead scientist in the concern about the risk of chronic disease in poor lifestyle individuals wrote, "Several lines of evidence indicate that realistic modifications of diet and lifestyle can prevent most CAD, stroke, diabetes, colon cancer, and smoking-related cancers".

And, "Among U.S. adults, more than 90 percent of type 2 diabetes, 80 percent of CAD, 70 percent of stroke, and 70 percent of colon cancer are potentially preventable by a combination of nonsmoking, avoidance of overweight, moderate physical activity, healthy diet, and moderate alcohol consumption".

Mustard is a genus Brassica, belongings to the family Brassicaceae, native to the Himalayan region of India. The veggie has seen used in some forms in African, Italian, Indian, Chinese, Japanese, and soul food cuisine because of its popularity.

With an aim to find natural food that lowers the incidence of chronic diseases including different kinds of cancer, researchers examined the anti-cancer effects of sulfur-containing glucosinolates (GLSs)-secondary plant compounds from mustards, including isothiocyanates.

According to medical literature, ITCs promoted overall health in vitro and in vivo. The phytochemical also exerted anti-carcinogenic and anti-inflammatory properties by activating the redox-sensitive transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) involved in the antioxidant expression. and phase II enzymes involved in drug metabolism.

Furthermore, the administration ITCs also significantly ameliorates a severe inflammatory phenotype in colitic mice in vivo.

In other words, ITCs inhibited the risk of chronic disease through their antioxidants and anti-chemical toxicity activity.

Researchers after taking other factors into account wrote, "an epigenetic mode of action for Brassica-derived phytochemicals, the conduction of further studies would be recommendable to investigate if the beneficial effects of these compounds also persist during an irregular consumption pattern".

Taken altogether, mustards processed abundantly ITCs may be considered supplements for the prevention and treatment of chronic diseases, pending the confirmation of the larger sample size and multicenter human study.

Intake of SFN as a supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Brassica-Derived Plant Bioactives as Modulators of Chemopreventive and Inflammatory Signaling Pathways by Sturm C1, Wagner AE. (PubMed)
(2) Chronic diseases and health promotion by WHO
(3) Chapter 44Prevention of Chronic Disease by Means of Diet and Lifestyle Changes by Walter C. Willett, Jeffrey P. Koplan, Rachel Nugent, Courtenay Dusenbury, Pekka Puska, and Thomas A. Gaziano. (NCBI)

#Antioxidant Betacyanins Protect the Liver Against the Risk of #LiverSteatosis, Researchers Say

By Kyle J. Norton

The liver is the largest internal organ that not only filters the blood coming from the intestinal system but also protects our body against chemical and drug toxicity.

Additionally, the liver also produces cholesterol that plays an essential role to aid digestion, producing vitamin D and steroid hormones and building strong cell membranes.

Believe it or not, the liver also produces antioxidant enzymes that inhibit free radical oxidation and interact with the hormone insulin to store glucose in the form of glycogen.

Hepatic steatosis is a condition caused by the accumulation of fat in the liver. Liver steatosis can be classified into 2 types

* Alcoholic liver steatosis is caused by over-consumption of alcohol over time.

* Non-Alcohol Steatosis (NASH) is a condition of accumulation of excess fat in the liver in people who drink little or no alcohol. ... Non-Alcohol Steatosis is considered a major cause of liver scarring and cirrhosis.

The most common symptoms of liver steatosis are jaundice, abdominal swelling (ascites), enlarged blood vessels just beneath the skin's surface, enlarged breasts in men, enlarged spleen, and red palms.

If you have some of the aforementioned symptoms, please check with your doctor to rule out the possibility.

Conventionally, there is no effective treatment for liver steatosis. Weight loss and weight management through a combination of a healthy diet and exercise are the most recommended.

Some researchers suggested that the rise of liver steatosis in the US may be correlated to the promotion of a high-fat diet over the past few decades.

Dr. Arisqueta L, the lead scientist wrote, "High-fat diet (HFD) feeding or leptin-deficient mice are extensively used as models resembling features of human nonalcoholic fatty liver disease (NAFLD)".


And, "The concurrence of experimental factors as fat content and source or total caloric intake leads to prominent differences in the development of the hepatic steatosis and related disturbances".


Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, chard, etc.

On finding a natural pigment for the prevention and treatment of liver steatosis, researchers examined whether betanin (from natural pigments, a member of betacyanins) had anti-oxidant properties against paraquat-induced liver injury in Sprague-Dawley rats.

Paraquat was injected intraperitoneally into rats to induce liver toxicity and randomly assigned to 4 groups: a control group, a paraquat group, and two groups received betanin at doses of 25 and 100mg/kg/day three days before and two days after administered paraquat.

Administration of betanin inhibited the elevated serum aspartate aminotransferase and alanine aminotransferase levels of the paraquat rats.

Betanin treated group also enhanced the production of antioxidant enzymes that counter the overexpression of free radicals-induced oxidative stress.

Furthermore, the betanin-treated group also increased the expression of an enzyme associated with detoxification.

Moreover, liver mitochondrial damage caused by paraquat injection also was reduced by the administration of betanin.

In other words, all parameters associated with the onset of liver damage that causes steatosis to develop were decreased substantially in the animals treated with betanin than in those who received paraquat alone.

Based on the results, researchers after taking other factors into account wrote, "Betanin had a protective effect against paraquat-induced liver damage in rats. The mechanism of the protection appears to be the inhibition of CYP 3A2 expression and protection of mitochondria".

Taken altogether, betacyanins processed abundantly bioactive ingredient betanin may be considered a remedy for the prevention and treatment of liver steatosis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of betacyanins as a supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Red pitaya betacyanins protect from diet-induced obesity, liver steatosis, and insulin resistance in association with modulation of gut microbiota in mice by Song H1,2, Chu Q1, Yan F1, Yang Y1, Han W1, Zheng X. (PubMed)
(2) White Pitaya (Hylocereus undatus) Juice Attenuates Insulin Resistance and Hepatic Steatosis in Diet-Induced Obese Mice by Song H1,2, Zheng Z1, Wu J1, Lai J1, Chu Q1, Zheng X. (PubMed)
(3) High-fat diet overfeeding promotes nondetrimental liver steatosis in female mice by Arisqueta L1, Navarro-Imaz H2, Labiano I3, Rueda Y2, Fresnedo O. (PubMed)

#CaffeinatedCoffee Inhibits #SkinAging by Increasing the Micro-Vascular Function in Skin, Scientists Reveal

By Kyle J. Norton

Moderate intake of caffeinated coffee regularly may have a particular effect in protecting the skin against aging, a joint institutes study suggested.

Skin aging is a natural process that cannot be reversed. However, by looking after our skin through a change of diet and lifestyle and reduced skin exposure to substances which have the potential to cause skin damage, skin aging process can be delayed.

Dr. Silke K. Schagen, the lead author in the study Discovering the link between nutrition and skin aging wrote, "Vitamins, carotenoids, tocopherols, flavonoids and a variety of plant extracts have been reported to possess potent antioxidant properties and have been widely used in the skincare industry either as topically applied agents or oral supplements in an attempt to prolong youthful skin appearance"


These results suggested that regular intake of fruits and vegetables with abundant nutrients and antioxidants may have a strong effect in delaying skin aging process.

Additionally, in the study of lifestyle and risk of skin aging in Japanese, Dr. Keiko Asakura, the lead scientist suggested, "Smoking status and topical sun protection were significantly associated with signs of visible skin aging in this study population"" (There are) significant differences between sexes in the severity of hyperpigmentation, texture, and pores, but not wrinkling".

More precisely, skin aging can be caused by a number of factors, including
* The intrinsic aging of the skin are factors that cannot be controlled, such as genes inherited from the parents, hormone change, and cellular recession due to aging.

* The extrinsic aging of the skin are factors that can or cannot be prevented, such as sun exposure, smoking, air pollution, bad eating habits, and physical inactivity.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.

In the review of coffee caffeine effect in skin blood flow, researchers at the study lead by the Linköping University showed that intake of caffeinated coffee exhibits a stronger expression in increased skin microvascular response to transdermal iontophoresis of acetylcholine (ACh)( non‐invasively introduce vasoactive drugs in regulating the neurotransmitter at neuromuscular junctions), in compared to decaffeinated coffee intake group.

The study also found that coffee caffeine intake displayed a significant effect on microvascular responses in increasing blood flow to the skin but decreasing blood flow in the fingertips, during the first hour after drinking;

These results suggested that caffeine in coffee showed an enormous activity in increasing blood flow to the body's skin.

In a double-blind, placebo-controlled, crossover study performed on 27 healthy volunteers with oral intake of a cup of either caffeinated or decaffeinated coffee and reactive hyperemia of finger blood flow assessed by laser Doppler flowmetry, within an interval of more than 2 days, the same experimental protocol was repeated with another coffee in a crossover manner, researchers showed that caffeinated coffee intake group demonstrated a slightly decreased finger blood flow in compared to decaffeinated coffee intake group.

According to the index of post-occlusive reactive hyperemia, microvascular endothelial function, in compared with decaffeinated coffee intake, the caffeine contained showed an important effect in enhanced microvascular function in healthy individuals.

Taking together, the findings suggested that the intake of coffee caffeine exerted a significant effect in promoting skin blood flow through a microvascular function which may have a strong impact in reducing the risk of skin aging.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Acute effects of coffee on skin blood flow and microvascular function by Tesselaar E1, Nezirevic Dernroth D2, Farnebo S3.(PubMed)
(2) Effect of caffeine contained in a cup of coffee on microvascular function in healthy subjects by Noguchi K1, Matsuzaki T2, Sakanashi M2, Hamadate N2, Uchida T2, Kina-Tanada M2, Kubota H2, Nakasone J2, Sakanashi M2, Ueda S3, Masuzaki H4, Ishiuchi S5, Ohya Y6, Tsutsui M7.(PubMed)
(3) Discovering the link between nutrition and skin aging by Silke K. Schagen,, † Vasiliki A. Zampeli, Evgenia Makrantonaki, and Christos C. Zouboulis. (PMC)
(4) Lifestyle Factors and Visible Skin Aging in a Population of Japanese Elders by Keiko Asakura,1 Yuji Nishiwaki,1 Ai Milojevic,1 Takehiro Michikawa,1 Yuriko Kikuchi,1Makiko Nakano,1 Satoko Iwasawa,1 Greg Hillebrand,2 Kukizo Miyamoto,2 Masaji Ono,3Yoshihide Kinjo,4 Suminori Akiba,5 and Toru Wakabayashi. (PMC)

#Polyphenols and Phenolicacids Found in #ThymeHoney Process Anti-#EndometrialCancer Activity, Scientists Suggest

By Kyle J. Norton

Honey may have a significant effect on reducing the risk and treatment of endometrial cancer, some scientists suggested.
Endometrial cancer is a chronic condition characterized by the irregular cell in the tissue of the endometrium.

Most cases of endometrial cancer start on the cells on the surface of the inner lining of the endometrium. At the advanced stage, after penetrating into the deeper layers, malignant cancer cells may travel a distance away to infect other healthy tissue and organs.

Endometrial cancer has been found to metastasize to the rectum, bladder, pelvic and para-aortic lymph nodes, and vagina.

The exact causes of endometrial cancer are unknown. Epidemiological studies suggested that the increase in age, more years of menstruation, never been pregnant, obesity, and the use of hormone therapy are some of the major prevalent risk factors associated with endometrial cancer.



Some researchers indicated that hormone change in the women's body such as higher androgen and estrogen levels and lower levels of progesterone due to polycystic ovarian syndrome (PCOs) also is a major cause of endometrial cancer.


Dr. Navaratnarajah R, the lead author in the concern of the association of polycystic ovarian syndrome (PCOs) and the risk of endometrial cancer, said, "Several studies have been published that appear to support this association, and it is common practice among gynecologists and physicians to prescribe hormonal treatment to reduce this perceived risk".

"The mechanism(s) underlying any association is also unclear, but it is again widely assumed that chronic anovulation, which results in continuous estrogen stimulation of the endometrium unopposed by progesterone, is a major factor".


These results clearly state that long-term overexpression of estrogen and reduced levels of progesterone are associated with the onset of the disease. However, the study of PCOs in the endometrial cancer risk should also be taken into account of obesity, hyperinsulinemia, and hyperandrogenism, which are also features of PCOS and risk factors for endometrial carcinoma.

In the association of PCOs and endometrial cancer mortality, the doctor team indicated, there is no evidence to link the increased mortality from endometrial cancer in women with the syndrome.

The study once again reaffirms the link of the estrogen therapy used in menopausal women for the treatment of climate symptoms. In other words, long-term high levels of estrogen compared to progesterone in the body are the major cause of endometrial cancer.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered healthy sweet food for replacing the use of white sugar and artificial sweetener

In finding a natural ingredient or whole food for the prevention and treatment of endometrial cancer, researchers examined honey's influence the oestrogenic activity.

The chemical composition and the potential of Greek honey extracts (thyme, pine, and fir honey) were classified to evaluate the most inhibitory activity against the endometrial cancer cells Ishikawa line.

Compared to other honey, thyme honey processes the highest total phenolics, phenolic acids, and hydroxymethylfurfural.

Thyme honey inhibited the expression of Ishikawa by reducing the cancer cell viability.

Moreover, the application of thyme honey also exerted a significant effect against Ishikawa and other cancer cell lines by inhibiting cancer cell proliferation, inducing apoptosis, and cell cycle arrest.


Furthermore, the inhibition of Thyme honey was also found to be associated with its function in the mediation of estrogen via modulation of the estrogen receptor activity, as estrogen agonists or antagonists in cancer cell lines in a tissue type-specific manner.

The efficacy of thyme honey anti-endometrial cancer was probably associated with its polyphenols and phenolic acids (vanillic acid and protocatechuic acid and p10 hydroxybenzoic acid) as these compounds have been proven to inhibit cancer-related pathways and processes

These results indicated that thyme honey monitored cell proliferation may be useful in cancer prevention, particularly, in endometrial cancer, through its agonist/antagonist properties.

Dr. Mari Jaakkola, the lead scientist in the conclusion of the study said, "Honey, especially the thyme honey, may be used as an alternative to sugar, while its incorporation in the human diet or as a food ingredient may prevent cancer-related processes, promoting thus the health of consumers".

Taken altogether, Thyme honey processed with major bioactive compounds polyphenols and phenolic acids may be considered a functional food for the prevention and combined with other primary therapy for the treatment of endometrial cancer without inducing any side effects.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma ISSN 0975-6299.

Sources
(1) Bioactivity of Greek honey extracts on breast cancer (MCF7), prostate cancer (PC3), and endometrial cancer (Ishikawa) cells: Profile analysis of extracts (Research Gate) PDF
(2) Polycystic ovary syndrome and endometrial cancer by Navaratnarajah R1, Pillay OC, Hardiman P. (PubMed)

#GreenTea' #Polyphenols (GTPs) in Attenuating the Risk of Osteoporosis through Their Antioxidant Activity in Vivos

By Kyle J. Norton

Green tea may have a therapeutic and positive effect in reduced onset. progression and treatment of osteoporosis, some scientists suggested.

Green tea is a precious drink that processes a number of health benefits known to almost everyone in Asia and the Western world.

Osteoporosis is a chronic condition characterized by progression in reduced bone mass and deterioration of bone tissue and is considered a major health problem in both elderly men and women.


In the study to evaluate the effects of ingestion of green tea and green tea's bioactive compounds in mitigating bone loss and risk of osteoporotic fractures in both elderly women and men, researchers found that the application of green tea and its bioactive compounds exert significant activities in the reduced onset of osteoporosis, through its antioxidants and its initiation of the production of natural antioxidant in the body such as glutathione and enzymes (e.g., catalase and superoxide dismutase) in inhibited the levels of ROS in facilitated the chain reaction.

Truly, the overexpression of free radicals has been associated with the change in the balance between activities of osteoblasts and osteoclasts, leading to osteoclasts in destroyed the calcified tissue and induced bone remodeling.

These results demonstrated a significant decrease in the risk of fracture by improving bone mineral density and preventing free radicals in damage the bone-forming osteoblasts while suppressing osteoclastic activities.

Moreover, in the review of the effect of green tea and its bioactive components on bone health, researchers indicated that ingestion of green and its bioactive compound displays an impressive Osteo-protective impact on bone mass and microarchitecture in various bone loss models associated with aging, sex hormone deficiency, and chronic inflammation.


The implication of reduced onset and progression of osteoporosis in the aging population due to sex hormone deficiency of the study may be attributed to green tea and its bioactive compound in increased levels of osteocalcin, a bone formation marker, decreased serum of tartrate-resistant acid phosphatase (TRAP), a bone resorption marker and improved the body in absorption of calcium.


In fact, the serum of serum levels of osteocalcin (OC) and tartrate-resistant acid phosphatase (TRAP) is considered an effective measurement of the rate of bone turnover in patients with osteoporosis.

Interestingly, the application of green tea and its bioactive compound was also found to modulate the expression of proinflammatory cytokines in the regulation of osteoblasts and osteoclasts, by inhibiting the production of C-reactive protein (CRP) production in the liver in demonstrated inflammation by reduced levels of interleukin-1 and 6(IL-1-6) and tumor necrosis factor-alpha (TNF-α), the sensitive markers of systemic inflammation.

This differentiation was supported by the study in the evaluation of the efficacy of green tea polyphenols (GTPs) at mitigating bone loss and microstructure deterioration along with related mechanisms in 40 androgen-deficient aged male rats, a model of male osteoporosis, randomly assigned to received A 2 (sham vs. orchidectomy) × 2 (no GTP and 0.5% GTP in drinking water) for 16 weeks.

At the end of the experiment, researchers found that rats treated with GTP demonstrate increased serum osteocalcin concentrations, bone mineral density, and trabecular volume, number, and strength of femur; increased trabecular volume and thickness and bone formation in both the proximal tibia and periosteal tibial shaft; decreased eroded surface in the proximal tibia and endocortical tibial shaft; and increased liver glutathione peroxidase activity.

These results indicated a strong implication of green tea polyphenols in decreased cortical and trabecular bone loss and increased both bone density by stimulated overexpression of bone formation and reduced bone resorption via antioxidant capacity.

Taken together, green tea and its bioactive polyphenols may be considered a functional food in ameliorated early-onset, progression and combined with standard medicine for the treatment of osteoporosis. However, the intake of green tea supplements should be taken with extreme care due to recent reports of acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Green tea and bone metabolism by Shen CL1, Yeh JK, Cao JJ, Wang JS. (PubMed)
(2) Green tea and bone health: Evidence from laboratory studies by Shen CL1, Yeh JK, Cao JJ, Chyu MC, Wang JS. (PubMed)
(3) Supplementation with green tea polyphenols improves bone microstructure and quality in aged, orchidectomized rats by Shen CL1, Cao JJ, Dagda RY, Tenner TE Jr, Chyu MC, Yeh JK.(PubMed)

#Antioxidant #Myricetin and #Quercitrin Found in #Cranberry Protects the Body Against Bacterial Infection in Vitro

By Kyle J. Norton

Infection is a condition caused by a harmful microbial invasion of the body's tissues
Most cases of bacterial infection are treated with antibiotics. However, bacterias are very adaptable, and overuse of antibiotics has been found to make them resistant to antibiotics.

Out of trillions of strains of bacteria in the world, only a few cause diseases in humans. Believe it or not, our gut contains trillion microorganisms, most of which are bacteria.

The most common symptoms of bacterial infection are redness and heat, swelling, fever, and pain at the site of infection.

In severe cases, the patient may also experience symptoms of swollen lymph glands.

Most cases of bacterial infection are treated successfully if the types of bacteria that cause the infection are identified.

There are many risk factors associated with the onset of bacterial infection, people with severe chronic disease may increase the prevalence of bacterial infection, particularly in those with cirrhosis.

Dr. Deschênes M, the lead scientist at the Université de Montréal wrote, "Bacterial infection is a frequent and severe complication of cirrhosis. Cirrhotic patients admitted for gastrointestinal bleeding are at high risk of such a complication and have been targeted in trials of antibiotic prophylaxis".

And, " patients with severe cirrhosis who are admitted for gastrointestinal bleeding have a higher risk of developing a bacterial infection during their hospitalization than other cirrhotic patients".

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the treatment of bacterial infection, researchers examined the effect of cranberry antibacterial activity against uropathogenic strains of Escherichia coli (UPEC).

According to the tested analysis, the whole extract showed a powerful antibacterial activity against UPEC compared to the selected fractions that presented a different behavior.

Myricetin and quercitrin demonstrated the highest decrease in E. coli biofilm formation compared with the control and other fractions.

However, other chemical constituents such as dihydro ferulic acid glucuronide, procyanidin A dimer, quercetin glucoside, myricetin, and prodelphinidin B led to a significant decrease of the surface hydrophobicity compared with the control.

In other words, all fractions in the cranberry extract worked synergistically to protect the host against the infection caused by E. coli

Based on the results, researchers said, "Apart from proanthocyanidins, other compounds, mainly flavonoids, can act against E. coli biofilm formation and also modify UPEC surface hydrophobicity in vitro."

Taken altogether, cranberry may be considered a remedy for the prevention and treatment of bacterial infection, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antibacterial activity of isolated phenolic compounds from cranberry (Vaccinium macrocarpon) against Escherichia coli by Rodríguez-Pérez C1, Quirantes-Piné R2, Uberos J3, Jiménez-Sánchez C1, Peña A4, Segura-Carretero A. (PubMed)
(2) In Vivo Consumption of Cranberry Exerts ex Vivo Antiadhesive Activity against FimH-Dominated Uropathogenic Escherichia coli: A Combined in Vivo, ex Vivo, and In Vitro Study of an Extract from Vaccinium macrocarpon by Rafsanjany N1, Senker J1, Brandt S1, Dobrindt U2, Hensel A. (PubMed)
(3) Risk factors for the development of bacterial infections in hospitalized patients with cirrhosis by Deschênes M1, Villeneuve JP. (PubMed)

#Coffee Intake Daily Reduces the Risk of #MetabolicSyndrome, Studies Fing

By Kyle J. Norton

Coffee consumed daily and regularly may have a substantial and potential effect in blocking the onset of metabolic syndrome, some scientists suggested.
Metabolic Syndrome is a group of risk factors associated with the development of cardiovascular disease and type 2 diabetes, including high blood pressure, abnormally high blood cholesterol, and triglyceride levels,.....

According to the statistic, about a quarter of the US population have metabolic syndrome, and the numbers are increasing at an alarming rate.

The Western diet with a high on saturated and trans, refined sugar, salt, and processed foods, is associated with the early onset of the condition.

Dr. Christos Pitsavos, in the evaluation of the effect of diet on the risk metabolic syndrome, wrote, "People with the metabolic syndrome may benefit from intensive lifestyle modifications including dietary changes and adopting a physically more active lifestyle".

These statements suggested that everyone can prevent the development of the syndrome through modification of their daily diet accompanied by a change to a healthy lifestyle.

The doctor continued, " During the last decades increasing scientific evidence has emerged that protective health effects can be obtained from diets that are rich in fruits, vegetables, legumes, and whole grains, and which include fish, nuts, and low-fat dairy products. Such diets need not be restricted in total fat intake as long as energy intake does not exceed caloric expenditure and if they emphasize predominantly vegetable oils that have a low content of saturated fats and partially hydrogenated oils".

Coffee, second to green tea, is a popular and social beverage all over the world, particularly in the West, made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.

According to the searching of a database of PubMed and the China National Knowledge Infrastructure (CNKI) for relevant articles published between 1 January 1999 and 31 May 2015, including 11 published reports and 13 studies with a total of 159,805 participants eligible for our meta-analysis, the relatively odd risk ratio of metabolic syndrome between the highest vs lowest category of coffee consumption was 0.872

The review also observed a nonlinear relationship between coffee and coffee caffeine consumption in the amelioration of risk of metabolic syndrome, by dose-response analysis.

Additionally, in a cross-sectional population-based survey of 8,821 adults (51.4% female) conducted in Krakow, Poland. to evaluate the coffee and tea consumption and risk of metabolic syndrome, using food frequency questionnaires, researchers after the observation of the questionnaire returned from participants expressed that there is an interesting association between high coffee consumption of 3 cups and the clusters of lower BMI, waist circumference, systolic and diastolic blood pressure, triglycerides, and higher HDL cholesterol compared to those drinking less than 1 cup/day.

The study apparently indicated that people drinking 3 cups of coffee daily and regularly have a favorably ameliorated risk of metabolic syndrome even after adjusting for potential confounding factors.

More importantly, the study also pointed out that high coffee consumption was negatively associated with waist circumference, hypertension, and triglycerides in women but not in men.

Furthermore, in the animal evaluation of the effect of coffee drinking on clinical markers of diabetes and metabolic syndrome in Zucker rats including Diabetic Zucker rats with metabolic syndrome and control Zucker rats, researchers at the Fluminense Federal Institute showed that animals received daily doses of coffee by gavage for 30 days express a substantially decreased risk of metabolic syndrome by reducing serum glucose, total cholesterol, and triglycerides, compared to non-treatment group.

Dr. Abrahão SA, the lead researcher said, "The results demonstrate that treatment with roasted coffee drink, because of its hypoglycemic and hypolipidemic effect, is efficient in the protection of animals with metabolic syndrome and diabetes mellitus type 2".

The findings from the above studies suggested that coffee drinking daily and regularly have a favorably profound effect in decreasing the risk of metabolic syndrome, particularly in women.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) Coffee consumption and risk of the metabolic syndrome: A meta-analysis by Shang F1, Li X1, Jiang X2.(PubMed)
(2) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Topor-Mądry R3, Pikhart H4, Szafraniec K3, Pająk A3.(PubMed)
(3) Diet, Exercise and the Metabolic Syndrome by Christos Pitsavos, Christos Pitsavos, Demosthenes Panagiotakos,, Michael Weinem, and Christodoulos Stefanadis. (PMC)