Saturday, 10 June 2023

#Healthyfood #FermentedCucumbers Balance of the Ratio of Microbiota Composition in Vitros, According to Studies

By Kyle J. Norton

The gut microbiome made up of trillions of microorganisms is the bacterial composition found in the gut of the digestive tract.

In a healthy individual, the ratio of the bacterial composition is balanced. In other words, the bad bacteria in the digestive tract are totally countered by the presence of good bacteria.

However, the imbalanced ratio of the composition of the gut microbiota has been associated with chronic diseases ranging from inflammatory bowel disease (IBD), obesity, and allergic disorders, in both human and animal models


Believe it or not, gut microbes have been found to influence many aspects of human health including immune, metabolic, and neurobehavioural traits.

In immunity, the balance of the gut microbes showed to stimulate the immune function against inflammatory immune disorders.

Digestively, balanced gut microbes protect the gut against gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria.


In metabolism, gut microbes influence what the human host is able to extract from its diet, such as nutrients, thus reducing the risk of obesity and obesity complications.

Neurologically, gut microbiota can control brain insulin signaling and metabolite levels that play a critical role in neurobehaviors.

Some researchers suggested, there are huge benefits that influence the function of the brain, immunity, heart, and digestive system and reduce the risk of chronic diseases and conditions such as diabetes and metabolic syndrome by maintaining a good ratio of the gut microbiome.

The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.

With an aim to discover a natural ingredient for balancing the ratio of microbiota composition, researchers investigated and evaluated cucumber phytochemical compositions along with their potential gut microbiota modulating, free radical scavenging, and anti-inflammatory capacities.

Seed flour extracts from cucumber enhanced the total number of gut bacteria by altering the abundance of specific bacterial phylum or genus in vitro.

In other words, cucumbers improved digestive functioning by enhancing the ratio of microbiota compositions in the gut.

Compared to broccoli and carrot seed flour extracts, cucumber seed extract showed the least effect in DPPH radical scavenging capacity, oxygen radical absorbing capacity, and hydroxyl radical (HO•) scavenging capacity values of 85, 634, and 270 μmol Trolox equivalent (TE)/g.

In the tested J774A.1 cells, cucumber suppressed the LPS-induced production of pro-inflammatory cytokines.

The results strongly suggested that the administration of Cucumis prevented colonic inflammation and improve digestive functioning by changing the gut microbiota composition.

In order to reveal more information about cumber in the improvement of gut microbiota, composition researchers examined Cucumis melo L. (Cucumis) on obesity-induced IR in genetically leptin-deficient Lepob/Lepob mice.

According to the tested assays, Cucumis improved IR and relieved inflammation in adipose tissue and blood which lead to the balance of the ratio of microbiota composition.

Dr. Lee D, the lead scientist after taking into account co and confounders wrote, "administration of Cucumis improved IR by reducing inflammation, thereby changing the gut microbiota composition".

Taken altogether, fermented cucumber may be used for the treatment of digestive dysfunction by improving the ratio of gut microbiota composition, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Therapeutic Effect of Cucumis melo L. Extract on Insulin Resistance and the Gut Microbiome in Lepob/Lepob Mice by Lee D1, Yoo JH1, Lee BC. (PubMed)
(2) Chemical Compositions of Cold-Pressed Broccoli, Carrot, and Cucumber Seed Flours and They're in Vitro Gut Microbiota Modulatory, Anti-inflammatory, and Free Radical Scavenging Properties by Choe U1, Li Y1,2, Gao B2, Yu L1, Wang TTY, Sun J, Chen P, Liu J3, Yu L1. (PubMed)

#Coffee Does Not Elevate the Dyspeptic Symptoms in Dyspepsia Patients, Studies Show

By Kyle J. Norton

In contrast to public belief, coffee, and coffee caffeine do not increase the risk of dyspepsia, but elevate symptoms of dyspepsia, a respectable university study postulated.
Dyspepsia is a condition of painful, difficult, or disturbed digestion, accompanying symptoms of nausea and vomiting, heartburn, bloating, and stomach discomfort.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.

A total of 30 coffee-sensitive individuals completed a single-center, randomized, double-blind, crossover study in the evaluated symptom of dyspepsia regarded both in the fasting state and after ingestion of a standard test meal. researchers found that both states exhibited certain effects in increased symptoms of dyspepsia after 2 cups of coffee intake.


According to the University of Nebraska Medical Center, coffee intake in the experiment model showed no significant differences in the frequency or severity of dyspepsia between the coffee brewed with coffee beans processed using conduction roasting in compared to other types of roasted coffee.


Dr. DiBaise JK, the lead author said, "differences in the coffee bean roasting process do not result in marked differences in coffee-induced upper gastrointestinal symptoms".

Additionally, in the comprised studies of coffee drinking habits of 58 duodenal ulcer patients, 55 non-ulcer dyspepsia patients, and 55 normal controls, researchers at the University of Michigan, filed the following reports

1. Intake of coffee daily in the experimental subjects showed no statistical difference between non-ulcer dyspepsia patients (55%) and controls.
2. The induced dyspepsia in these participants showed no difference in caffeine and decaffeinated coffee intake
3. Furthermore, dyspepsia was not associated with the number of cups per day, the method of preparation, the length of time of coffee use, or any change in coffee intake in the previous year.
4. The prevalence of coffee induction of dyspeptic symptoms was much more common in non-ulcer dyspepsia patients (53%) than in controls (22%).
Dr. Elta GH, the lead researcher said, "Patients with non-ulcer dyspepsia,....... were more likely to experience dyspeptic symptoms after coffee ingestion".

Taking together, coffee regardless of type does not exhibit risk but elevated symptoms of dyspepsia. According to the Royal Adelaide Hospital, identifying specific foods as triggers of the symptoms, and making behavioral adjustments in the daily diet and lifestyle change may improve symptoms, including reduced intake of implicated foods such as milk and dairy products, citrus fruits, spicy foods, coffee, and alcohol.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A randomized, double-blind comparison of two different coffee-roasting processes on the development of heartburn and dyspepsia in coffee-sensitive individuals by DiBaise JK1.(PubMed)
(2) Comparison of coffee intake and coffee-induced symptoms in patients with duodenal ulcer, non=ulcer dyspepsia, and normal controls by Elta GH1, Behler EM, Colturi TJ.(PubMed)
(3) Dietary and lifestyle factors in functional dyspepsia by Feinle-Bisset C1, Azpiroz F.(PubMed)

#Garbanzo beans(#Chickpeas) Reduce the Risk of Dyslipidemia and Diseases Associated with High Blood Cholesterol, Researchers Find

By Kyle J. Norton

Garbanzo beans also known as chickpeas are an edible legume of the genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to the Middle East.

The effectiveness of chickpeas in reducing the symptoms and complications of patients with high blood cholesterol is probably due to the existence of the high amount of dietary fiber. According to the Huazhong Agricultural University, dietary fiber has the potential to be used as a functional ingredient to control cardiovascular disease. due to the effectiveness of lipid-binding capacities of the three fibers and their effects on serum and hepatic lipid profiles.

In total, 157 patients study, dietary fiber intake may have a protective factor associated with CVD, through reduction of the levels of pro-inflammatory factors, indoxyl sulfate, and serum cholesterol.

The study of the dietary fiber in the prevention of obesity-related liver lipotoxicity, Dr. Han S and research team in the joint study led by Soochow University wrote," Adequate intake of dietary fibers has proven metabolic and cardiovascular benefits,.... (and) exhibited lower weight gain, lipid profiles, and insulin resistance.

In an animal study, the change of diet such as high fiber diet may completely normalize neuropathy, promote weight loss, improved insulin sensitivity, and restored LDL cholesterol and oxLDL by 50% compared with levels in HFD control mice with metabolic syndrome (obesity, dyslipidemia, hypertension and impaired glucose tolerance (IGT)).

Taking all together, an increased intake of dietary fiber every day such as chickpeas may reduce the risk of dyslipidemia as well as high blood cholesterol-induced diseases.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Tea Dietary Fiber Improves Serum and Hepatic Lipid Profiles in Mice Fed a High Cholesterol Diet by Guo W1, Shu Y1, Yang X2.(PubMed)
(2) Dietary fiber intake is associated with chronic kidney disease (CKD) progression and cardiovascular risk, but not protein nutritional status, in adults with CKD by Lu L1,2,3, Huang YF4, Wang MQ2, Chen DX1,2,3, Wan H5, Wei LB1,2,3, Xiao W6.(PubMed)
(3) Dietary fiber prevents obesity-related liver lipotoxicity by modulating sterol-regulatory element binding protein pathway in C57BL/6J mice fed a high-fat/cholesterol diet by Han S1, Jiao J1, Zhang W1, Xu J2, Wan Z1, Zhang W3, Gao X4, Qin L1.(PubMed)
(4) Dietary reversal of neuropathy in a murine model of prediabetes and metabolic syndrome by Hinder LM1, O'Brien PD1, Hayes JM1, Backus C1, Solway AP1, Sims-Robinson C2, Feldman EL3.(PubMed)

#Healthyfood #NavyBean #FermentedExtracts Show a Strong Effect in the Inhibition of #Hypertension, Studies Show

By Kyle J. Norton

High blood pressure or hypertension is a medical condition characterized by abnormally high blood pressure in the arteries. High blood pressure is also a condition in the cluster of metabolic syndrome that increases the risk of heart disease, stroke, and diabetes.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

Although high blood pressure usually does not cause symptoms at the early stage, in some extreme cases patients may experience dizziness and light head, shortness of breath, nosebleeds, flushing, chest pain, and visual changes.

Underlying medical conditions such as kidney disease and long-term stress are associated with high blood pressure.

More precisely, according to the American Hypertension Association, long-term untreated high blood pressure can induce complications such as
* Heart attack is caused damaged by damaged arteries due to high blood pressure that leads to blockage or limited blood flow to the heart muscle.

* Stroke, damaged blood vessels in the brain may be clogged and burst.

* Heart failure and high blood pressure increase the risk of an enlarged heart that limits the heart function in blood circulation

Conventional hypertensive medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects.

If you are currently taking hypertensive medicine, please make sure you know all the side effects of the preventive measure.

Some researchers also found that excessive energy intake and obesity are major causes of hypertension.

Dr. Savica V, the lead author in the study "The effect of nutrition on blood pressure" wrote, "Obesity is associated with increased activity of the renin-angiotensin-aldosterone and sympathetic nervous systems, possibly other mineralocorticoid activity, insulin resistance, salt-sensitive hypertension, and excess salt intake, and reduced kidney function".

High sodium chloride intake strongly predisposes to hypertension".

"Increased alcohol consumption may acutely elevate blood pressure. High intakes of potassium, polyunsaturated fatty acids, and protein, along with exercise and possibly vitamin D, may reduce blood pressure".

The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed worldwide due to its numerous health benefits.

To find a potential ingredient for the treatment of hypertension, researchers investigated the inhibitory activities of the navy bean by preparation of navy bean milk (NBM) subjected to fermentation of four lactic acid bacteria (LAB) strains, namely, Lactobacillus helveticus MB2-1, Lactobacillus plantarum B1-6, and Lactobacillus plantarum 70810.

According to the tested assays, all fermented NBM showed higher angiotensin I-converting enzyme (ACE) inhibitory activity compared to the unfermented ones.

By comparison of each strain, researchers found that 2 h, 3 h, and 5 h are the optimum fermentation periods for respectively L. plantarum 70810, L. plantarum B1-6, and L. bulgaricus.

Compared to the IC value without causing an intestinal disturbance, the extracts fermented by L. plantarum B1-6 exerted the lowest IC50 value of 21 ± 2.1 μg protein ml(-1).

Angiotensin-converting enzyme (ACE) is a central component of the renin-angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body.


In other words, the effect of LAB fermentation on the degradation of navy lean proteins and the capacity to release ACE inhibitory peptides may have a strong effect on the inhibition of hypertension.

Dr. Rui X, after taking other factors into account wrote, "The approach was promising to obtain probiotic products with the potential to serve as functional ingredients targeting hypertension".


Taken altogether, the fermented navy bean may be considered a remedy for the prevention and treatment of hypertension, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best Before it's news, the karateKarate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Enrichment of ACE inhibitory peptides in navy bean (Phaseolus vulgaris) using lactic acid bacteria by Rui X1, Wen D, Li W, Chen X, Jiang M, Dong M. (PubMed)
(2) The effect of nutrition on blood pressure by Savica V1, Bellinghieri G, Kopple JD(PubMed)

#Healthyfood #Lentils In the Inprovement of The Diet Quality, According to Studies

By Kyle J. Norton

Intake of lentils frequently and daily may have a substantial and positive effect on improved diet quality, recent recommendations and guidance suggested.

Lentil, a type of pulse or tiny legume that can be cooked quickly and rich in protein and fiber is a bushy annual plant of genus Lens to the Fabaceae family, native to the Middle East.

The differentiation of lentils in the improvement of diet quality may be observed through several different aspects and implications.

According to the review of published medical literature online of MEDLINE, EMBASE, CINAHL, and the Cochrane Library for relevant controlled trials of >or=7 days, dietary non-oil-seed pulses (chickpeas, beans, peas, lentils, etc.) are a good source of slowly digestible carbohydrate, fiber and vegetable protein and a valuable means of lowering the glycaemic-index (GI) of the diet.

Further examination of the selected trials and studies satisfied the criteria and guideline of 41 trials (39 reports), found that studies using pulses alone (11 trials demonstrated a significant effect in reduced fasting blood glucose (FBG) and improved insulin levels, in compared to pulses in low-GI diets (19 trials) in lowered glycosylated blood proteins (GP), expressed blood glucose to the red blood cells, observed by HbA(1c) in the measurement of three-month average plasma glucose concentration or fructosamine, in the measurement of glucose levels over the previous 2-3 week and pulses in high-fiber diets (11 trials) lowered FBG and GP.

Observation of the outcomes of the trials and studies obtained indicated a significant effect of pulses in high-fiber diets in reduced risk of overexpression of glucose levels in the tested subjects in comparison to the other 2 groups.

After taking into account other confounders such as high inter-study quality and unexplained outcomes, Dr. Mitchell DC, the lead author said, "Pooled analyses demonstrated that pulses, alone or in low-GI or high-fiber diets, improve markers of longer-term glycaemic control in humans, with the extent of the improvements subject to significant inter-study heterogeneity".

According to the recommendation of The US Department of Agriculture's (New) MyPyramid guidelines, doubling dietary intake for vegetables, particularly, in subgroups of vegetables, including dry beans, peas, and lentils.

Even though dry beans, peas, and lentils were found to contain a rich source of nutrients and phytochemicals that have been shown to have beneficial health effects by several respectable institutes and recommended by health advocates, consumption levels in the United States are quite low.

The review from the National Health and Nutrition Examination Study (NHANES) found that only 0.9% of adolescents, 2.2% of adult men, and 3.5% of adult women met their dietary guidelines for both fruits and vegetables, compared to the EU-28, with average a third (34.4 %) of the population aged 15 or over did not consume any fruit or vegetables in a day; half (51.4 %) the population ate daily from 1 to 4 portions of fruit and vegetables, while the residual 14.1 % consumed more than 5 portions a day.

In the study to assess nutrient and food group intakes of dry bean and pea consumers compared to nonconsumers using data of dietary intake from 1999-2002 of National Health and Nutrition Examination Survey for adults aged > or =19 years, researchers surprisingly found that only 7.9% of adults are consuming dry beans and peas every day. Dry beans or peas intake showed significant fiber, protein, folate, zinc, iron, and magnesium levels and lowered saturated fat and total fat consumption. Most Mexican Americans or other Hispanics are more likely to be consumers than nonconsumers.

After an in-depth differentiation of the data, Dr.Mitchell DC, the lead scientist said, "These data support the specific recommendation for dry beans and peas as part of the overall vegetable recommendation" and "Increased consumption of dry beans and peas-economical and nutrient-rich foods could improve the diet quality of Americans".

Taken together, there is no doubt that the diet of lentils and other dry beans and peas may substantially affect improved diet quality for the population in all nations.

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.

Source
(1) Effect of non-oil-seed pulses on glycaemic control: a systematic review and meta-analysis of randomized controlled experimental trials in people with and without diabetes by Sievenpiper JL1, Kendall CW, Esfahani A, Wong JM, Carleton AJ, Jiang HY, Bazinet RP, Vidgen E, Jenkins DJ.(PubMed)
(2) Consumption of dry beans, peas, and lentils could improve diet quality in the US population by Mitchell DC1, Lawrence FR, Hartman TJ, Curran JM.(PubMed)
(3) Increasing Fruit and Vegetable Consumption: Challenges and Opportunities by Sandeep Sachdeva, Tilak R Sachdev, and Ruchi Sachdeva(PMC)
(4) The fruit and vegetable sector in the EU - a statistical overview, Data extracted in July and August 2016. Most recent data: Further Eurostat information, Main tables and Database.

#Healthyfood #CollardGreens Inhibits the Parameters Associated with Obese #FatAccumulation in Vivos, Researchers Suggest

By Kyle J. Norton

Obesity is a chronic condition characterized by excess body fat that has accumulated over time. People with a BMI of over 30 are considered obese.

Similarly, overweight is a condition of excess body weight relative to height. People with a BMI ranging from 25 to 29.9 is considered overweight.

According to the statistics, 68% of the American population is either overweight or obese. Obesity has been found to induce adverse effects nearly every system of the human body, leading to an increased risk of numerous diseases, including diabetes and cardiovascular disease.

Furthermore, the rate of obesity in the US and Canada continues to climb at an alarming rate, leading to significant burdens to the country's economy and health care system.

Epidemiologically, the most common symptoms of obesity are breathlessness, increased sweating, inability to cope with physical activity, feeling very tired every day, back and joint pains, low confidence, and self-esteem, and feeling isolation

According to the CDC, the most common complications associated with obesity are coronary heart disease, stroke, type 2 diabetes, cancer of breast, colon, endometrial, gallbladder, kidney, and liver and sleep apnea.

Currently, there is no effective treatment for the disease. However, some researchers suggested that combat the powerful environmental factors that influence eating and physical activity may be the best approach to reduce the risk of obesity.

Bariatric surgery is used as an option for management that causes a reduction in the amount of food you are or a reduction in the absorption of calories from the food you eat, or both.


The surgery has been proposed for patients with extreme obesity (BMI of 40 or higher) due to weight-induced a serious weight-related health problem, such as diabetes or high blood pressure.

Furthermore, this type of surgery has posed a serious risk to many patients if the commitment to making lifelong changes in their eating and exercise habits cannot be followed through.

Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.

With an aim to find a natural food for the prevention and treatment of obesity, researchers examined the effect of sulforaphane found abundantly in collard greens.


In a high-fat diet (HFD)-induced obesity in C57BL/6N mice that were fed a normal diet (ND), HFD or HFD plus 0.1% sulforaphane (SFN) for 6 weeks, researchers found that SFN administration not only attenuated HFD-induced visceral adiposity that stored around a number of important internal organs such as the liver, pancreas and intestines, adipocyte hypertrophy associated with an enlargement of adipose tissue but also ameliorated fat accumulation in the liver.

Furthermore, SFN decreased the elevated levels of serum total cholesterol and leptin, and liver triglyceride in HFD-SFN-fed mice compared to HFD-fed mice.

SFN also inhibited the expression of a gene associated with the promotion of inflammation in the adipose tissue of HFD-SFN mice and increased the adiponectin function in regulating glucose levels and fatty acid breakdown.

Moreover, reductase expression associated with the production of cholesterol was decreased and an antibody associated with fatty acid utilization was increased in lycopene treat group compared with HFD-fed mice.

Taken altogether, collard green processed abundantly SFN may be considered supplements for the prevention and treatment of obesity, pending confirmation of the larger sample size and multicenter human study.

Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Potential effects of sulforaphane to fight obesity by Martins T1, Colaço B1,2, Venâncio C1,2, Pires MJ1,3, Oliveira PA1,3, Rosa E1, Antunes LM. (PubMed)
(2) Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice by Kyeong-Mi Choi, Youn-Sun Lee, Wonkyun Kima, Seung Jung Kimb, Kyong-Oh Shina, Ji-YeonYuc, Mi Kyeong Lee, Yong-Moon Lee, Jin Tae Honga, Yeo-PyoYuna, Hwan-SooYooa. (Science Direct)

#Phytochemical #Betanin Processes a Strong #FreeRadicalScavenging Activities, Researchers Say

By Kyle J. Norton

Antioxidants are stable atoms that inhibit oxidation caused by free radicals.

Free radical scavengers are types of antioxidants that inhibit free radicals before they can orchestrate a chain reaction that can not be stopped until all electrons in the outermost ring are paired or inhibited by antioxidants.

Oxidative stress is associated with chronic disease due to the imbalanced ratio of free radicals and antioxidants produced by the host including heart disease, stroke, and diabetes.

Antioxidants besides produced by the body, they can also come into the body dietary sources.

In a healthy individual, an antioxidant produced by the body is good enough to counter the expression of free radicals induced by cell metabolism and free radicals induced by the environment such as the air we breathe and the food we eat.

However, for people with a weakened immune system, intake of antioxidants from outside sources such as fruits and vegetables can be helpful.

Believe it or not. moderate free radicals in the body are necessary for body functioning, including the promotion of heart function in blood circulation.

The most common types of free radical scavengers include
* Catalases, the very important enzyme is produced by the host that protects the cell from oxidative damage by free radicals.

*Glutathione peroxidase, is a cytosolic enzyme produced by the host that dissolves hydrogen peroxide to water and oxygen and peroxide radicals to alcohols and oxygen.

*Superoxide dismutase (SOD), is also produced by the host that dissolves superoxide radicals into either ordinary molecular oxygen or hydrogen peroxide.

*Vitamin E, Vitamin C, and vitamin D.

Betanin is phytochemicals in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains, found abundantly in beets, chard, etc.

In the urgency to find a natural compound for the treatment of diseases associated with overexpression of free radicals, researchers examined the betanin free radical scavenging activity.

According to the Trolox equivalent antioxidant capacity (TEAC) assay, at a pH > 4, betanin is about 1.5-2.0-fold more active to scavenge free radical compared to those of anthocyanins.

More precisely, the exceptionally high antioxidant activity of betanin was associated with an increase of its H-donation and electron-donation ability, totally depending on the expression of cationic state to mono-, di- and tri-deprotonated states present at essential solutions.


In other words, the efficacy of betanin's high free radical scavenging activity was dependent on the pH levels.

Taken altogether, betanin may be considered supplements for the prevention and treatment of diseases associated with oxidative stress, pending to the confirmation of larger sample size and multicenter human study.

Intake of betanin in supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Betanin, the main pigment of red beet: molecular origin of its exceptionally high free radical-scavenging activity by Gliszczyńska-Swigło A1, Szymusiak H, Malinowska P. (PubMed)
(2) Betacyanins as phenol antioxidants. Chemistry and mechanistic aspects of the lipoperoxyl radical-scavenging activity in solution and liposomes by Tesoriere L1, Allegra M, Gentile C, Livrea MA. (PubMed)