By Kyle J. Norton
Gut microbiota is a community of microbes living in the gastrointestinal tract, including at least 1000 different species of known bacteria with more than 3 million genes.
In a healthy individual, the ratio of good and bad microbes in the gut is balanced. However, people who have a psychological condition such as anxiety, and depression, and are under constant stress and long-term use of antibiotics, particularly your diet may have a negative impact on the ratio.
More precisely, under normal conditions, gut microbiota plays a critical role in overall health,
* Gut microbiota improves the absorption of dietary nutrients in the digestive system
* Gut microbiota protects the body against xenobiotics and drug toxicity by facilitating excretion.
* Gut microbiota also maintains the structural integrity of the gut mucosal barrier by enhancing the epithelial cells that protect the intestine against invasive pathogens and ensure the function of intestinal in nutrient adsorption.
* Gut microbiota interacts with the immune system against inflammatory immune disorders and inhibits the risk of gastrointestinal diseases and non-gastrointestinal diseases caused by overexpression of bad bacteria.
However, imbalanced the ratio of gut microbiota may have a negative impact on human health and diseases.
Epidemiological studies suggested imbalanced gut microbiota dysbiosis found in overweight and obese has been found to promote diet-induced obesity and metabolic complications.
Dr. Karina Al-Ass wrote, "Obesity is a worldwide epidemiologic syndrome characterized by fat mass accumulation, mainly visceral fat. Current thinking considers the potential role of gut microbiota on the development of obesity and its related comorbidities"
And " Gut microbiota can influence energy extraction from food, lipid metabolism, immune response, and endocrine functions and its profile has shown to differ between obese and lean subjects".
A recent joint study led by the Tianjin Medical University, General Hospital, an onion supplement may be potent to improve gut microflora and intestinal histomorphology on an animal model.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
The study included a total of 300 12-day-old broiler chicks (Ross) that were randomly divided into four groups as A served as the control without any supplementation, and B, C, and D received supplemented with onion powder at the rate of 1.5, 2 and 2.5g/kg of feed respectively.
Based on the tested results,* Supplementation of onion exerted a significantly (P<0.05) increased weight gain and feed consumption compared to the control.
* Furthermore, supplementation of onion significantly inhibited the population of E. coli and increased significantly Lactobacillus and Streptococcus species.
In other words, onion supplement promotes colon health by improving the ratio of gut microbiota.
* More importantly, injection of onion supplement also significantly increases the morphometry of length, width, crypt depth, and surface area of the villus in the duodenum, jejunum, and ileum of the small intestine associated with colon health optimization.
Based on the findings, researchers said, "Onion supplementation in broiler produced a positive effect on performance, gut microflora, and intestinal histomorphology".
Taken altogether, onion processed with a higher amount of onionin A (ONA) may be considered a remedy for the promotion of colon health, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of Quercetin Monoglycosides on Oxidative Stress and Gut MicrobiotaDiversity in Mice with Dextran Sodium Sulphate-Induced Colitis by Hong Z1, Piao M. (PubMed)
(2) In vivo effects of Allium cepa L. on the selected gut microflora and intestinal histomorphology in broiler by Ur Rahman S1, Khan S1, Chand N1, Sadique U2, Khan RU. (PubMed)
(3) Gut microbiota and obesity by Karina Al-Assal, Ana Cristina Martinez, Raquel SusanaTorrinhas, Camila Cardinelli, Dan Waitzberg. (Science Direct)
Thursday, 8 June 2023
#Healthyfood #CollardGreens Inhibit the Fat Accumulation in the Liver of Obese in Vivos, Researchers Say
By Kyle J. Norton
Obesity is a chronic condition characterized by excess body fat that has accumulated over time. People with a BMI of over 30 are considered obese.
Similarly, overweight is a condition of excess body weight relative to height. People with a BMI ranging from 25 to 29.9 is considered overweight.
According to the statistics, 68% of the American population is either overweight or obese. Obesity has been found to induce adverse effects in nearly every system of the human body, leading to increased risk of numerous diseases, including diabetes and cardiovascular disease.
Furthermore, the rate of obesity in the US and Canada continues to climb at an alarming rate, leading to significant burdens to the country's economy and health care system.
Epidemiologically, the most common symptoms of obesity are breathlessness, increased sweating, inability to cope with physical activity, feeling very tired every day, back and joint pains, low confidence, and self-esteem, and feeling isolation
According to the CDC, the most common complications associated with obesity are coronary heart disease, stroke, type 2 diabetes, cancer of the breast, colon, endometrial, gallbladder, kidney, and liver, and sleep apnea.
Currently, there is no effective treatment for the disease. However, some researchers suggested that combating the powerful environmental factors that influence eating and physical activity may be the best approach to reducing the risk of obesity.
Bariatric surgery is used as an option for management that causes a reduction in the amount of food you are or a reduction in the absorption of calories from the food you eat, or both.
The surgery has been proposed for patients with extreme obesity (BMI of 40 or higher) due to weight-induced serious weight-related health problems, such as diabetes or high blood pressure.
Furthermore, this type of surgery has posed a serious risk to many patients if the commitment to making lifelong changes in eating and exercise habits cannot be followed through.
Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.
With an aim to find a natural food for the prevention and treatment of obesity, researchers examined the effect of sulforaphane found abundantly in collard greens.
In a high-fat diet (HFD)-induced obesity in C57BL/6N mice that were fed a normal diet (ND), HFD or HFD plus 0.1% sulforaphane (SFN) for 6 weeks, researchers found that SFN administration not only attenuated HFD-induced visceral adiposity that stored around a number of important internal organs such as the liver, pancreas and intestines, adipocyte hypertrophy associated with an enlargement of adipose tissue but also ameliorated fat accumulation in the liver.
Furthermore, SFN decreased the elevated levels of serum total cholesterol and leptin, and liver triglyceride in HFD-SFN-fed mice compared to HFD-fed mice.
SFN also inhibited the expression of a gene associated with the promotion of inflammation in the adipose tissue of HFD-SFN mice and increased the adiponectin function in regulating glucose levels and fatty acid breakdown.
Moreover, reductase expression associated with the production of cholesterol was decreased and an antibody associated with fatty acid utilization was increased in the lycopene treatment group compared with HFD-fed mice.
Taken altogether, collard green processed abundantly SFN may be considered supplements for the prevention and treatment of obesity, pending the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Potential effects of sulforaphane to fight obesity by Martins T1, Colaço B1,2, Venâncio C1,2, Pires MJ1,3, Oliveira PA1,3, Rosa E1, Antunes LM. (PubMed)
(2) Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice by Kyeong-Mi Choi, Youn-Sun Lee, Wonkyun Kima, Seung Jung Kimb, Kyong-Oh Shina, Ji-YeonYuc, Mi Kyeong Lee, Yong-Moon Lee, Jin Tae Honga, Yeo-PyoYuna, Hwan-SooYooa. (Science Direct)
Obesity is a chronic condition characterized by excess body fat that has accumulated over time. People with a BMI of over 30 are considered obese.
Similarly, overweight is a condition of excess body weight relative to height. People with a BMI ranging from 25 to 29.9 is considered overweight.
According to the statistics, 68% of the American population is either overweight or obese. Obesity has been found to induce adverse effects in nearly every system of the human body, leading to increased risk of numerous diseases, including diabetes and cardiovascular disease.
Furthermore, the rate of obesity in the US and Canada continues to climb at an alarming rate, leading to significant burdens to the country's economy and health care system.
Epidemiologically, the most common symptoms of obesity are breathlessness, increased sweating, inability to cope with physical activity, feeling very tired every day, back and joint pains, low confidence, and self-esteem, and feeling isolation
According to the CDC, the most common complications associated with obesity are coronary heart disease, stroke, type 2 diabetes, cancer of the breast, colon, endometrial, gallbladder, kidney, and liver, and sleep apnea.
Currently, there is no effective treatment for the disease. However, some researchers suggested that combating the powerful environmental factors that influence eating and physical activity may be the best approach to reducing the risk of obesity.
Bariatric surgery is used as an option for management that causes a reduction in the amount of food you are or a reduction in the absorption of calories from the food you eat, or both.
The surgery has been proposed for patients with extreme obesity (BMI of 40 or higher) due to weight-induced serious weight-related health problems, such as diabetes or high blood pressure.
Furthermore, this type of surgery has posed a serious risk to many patients if the commitment to making lifelong changes in eating and exercise habits cannot be followed through.
Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.
With an aim to find a natural food for the prevention and treatment of obesity, researchers examined the effect of sulforaphane found abundantly in collard greens.
In a high-fat diet (HFD)-induced obesity in C57BL/6N mice that were fed a normal diet (ND), HFD or HFD plus 0.1% sulforaphane (SFN) for 6 weeks, researchers found that SFN administration not only attenuated HFD-induced visceral adiposity that stored around a number of important internal organs such as the liver, pancreas and intestines, adipocyte hypertrophy associated with an enlargement of adipose tissue but also ameliorated fat accumulation in the liver.
Furthermore, SFN decreased the elevated levels of serum total cholesterol and leptin, and liver triglyceride in HFD-SFN-fed mice compared to HFD-fed mice.
SFN also inhibited the expression of a gene associated with the promotion of inflammation in the adipose tissue of HFD-SFN mice and increased the adiponectin function in regulating glucose levels and fatty acid breakdown.
Moreover, reductase expression associated with the production of cholesterol was decreased and an antibody associated with fatty acid utilization was increased in the lycopene treatment group compared with HFD-fed mice.
Taken altogether, collard green processed abundantly SFN may be considered supplements for the prevention and treatment of obesity, pending the confirmation of the larger sample size and multicenter human study.
Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Potential effects of sulforaphane to fight obesity by Martins T1, Colaço B1,2, Venâncio C1,2, Pires MJ1,3, Oliveira PA1,3, Rosa E1, Antunes LM. (PubMed)
(2) Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice by Kyeong-Mi Choi, Youn-Sun Lee, Wonkyun Kima, Seung Jung Kimb, Kyong-Oh Shina, Ji-YeonYuc, Mi Kyeong Lee, Yong-Moon Lee, Jin Tae Honga, Yeo-PyoYuna, Hwan-SooYooa. (Science Direct)
#Antioxidant #Allicin in the Normalization of #BloodPressure, According to Studies
By Kyle J. Norton
Scientists may have found a natural bioactive ingredient for the prevention and treatment of hypertension with no side effects, according to the studies.
Hypertension is a medical condition characterized by abnormally high blood pressure.
Acute high blood pressure is a risk of high blood pressure caused by sudden stress or physical activity in the short term that will eventually fall back to normal levels.
Chronic hypertension is a persistence of elevated high blood pressure which cannot be decreased without medication.
Chronic hypertension is one of the members of the cluster of conditions associated with metabolic syndrome and a major cause of cardiovascular disease.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
Some researchers suggested that hypertension may be caused by certain medical conditions, such as kidney disease, however, the cause of the syndrome is more likely as a result of an unhealthy lifestyle.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects.
Therefore, if you are currently taking medicine for the treatment of hypertension, please make sure you know all side effects for preventive measures.
Dr. Beilin LJ, at the University Department of Medicine, and West Australian Heart Research Institute in the examine the lifestyle risk of hypertension wrote, High salt intakes remain a major contributor to hypertension, especially when potassium intake is low. Smoking has a dominant effect in increasing cardiovascular risk in hypertensives ".
And, "Clustering of risk factors is often associated with clustering of unhealthy lifestyle characteristics and both are most prominent in lower socio-economic groups and in Developing Countries adopting a more sedentary lifestyle and Western diet patterns".
This statement clearly suggested that by making changes to lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.
Allicin is phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in onion and garlic.
On finding a natural compound for the prevention and treatment of high blood pressure, one of the major conditions associated with the onset of cardiovascular disease, researchers examined the antihypertensive phytochemical allicin isolated from garlic.
The study included nine patients with rather severe hypertension (diastolic blood pressure > or = 115 mm Hg).
Administrated garlic preparation including 1.3% allicin at a large dose (2400 mg) showed a sitting blood pressure fall of 7/16 (+/- 3/2 SD) mm Hg at peak effect approximately 5 hours after the dose.
From 5-14 hours after the dose, the preparation significantly decreased the diastolic blood pressure with no side effects.
Dr. McMahon FG, the lead scientist said, "Our results indicate that this garlic preparation can reduce blood pressure", after taking into account other factors.
Furthermore, in a total of 84 men with mild or moderate arterial hypertension, researchers compared the antihypertensive effects of time-released garlic powder tablets (Allicor) with that of regular garlic pills (Kwai)in a double-blind, placebo-controlled trial with an active control arm.
After an 8-week placebo treatment run-in phase, patients were randomized either to 600 mg Allicor (n=30) or to placebo (n=20) daily for 8 weeks In addition, in the open-label branch, patients received either 2400 mg Allicor daily (n=18) or 900 mg Kwai daily (n=16).
Allicor treatment at a dose of t600 mg daily showed a decrease of both systolic and diastolic blood pressures by 7.0 mm Hg (95% confidence interval (95% CI): 5.3-8.7) and 3.8 mm Hg (95% CI: 2.7-4.8), respectively.
However, Increasing the Allicor dosage to 2400 mg daily did not provide any additional benefit.
Treatment with Kwai exerted a similar effect in decreasing systolic blood pressure (5.4 mm Hg, 95% CI: 1.9-8.8) as those of Allicor, but no decrease in diastolic blood pressure.
The results clearly indicated that Allicor may process the prolonged action that was found in the Kwai treatment group.
Dr. Sobenin IA, the lead scientist wrote in the final report, "Time-released garlic powder tablets are more effective for the treatment of mild and moderate arterial hypertension than are regular garlic supplements".
Taken altogether, allicin, a bioactive compound processed with antihypertensive properties may be used for the prevention and treatment of high blood pressure, pending the validation of a large sample size and multicenter study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Can garlic lower blood pressure? A pilot study by McMahon FG, Vargas R.(PubMed)
(2) Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension by Sobenin IA, Andrianova IV, Fomchenkov IV, Gorchakova TV, Orekhov AN. (PubMed)
(3) Lifestyle and hypertension--an overview by Beilin LJ. (PubMed)
Scientists may have found a natural bioactive ingredient for the prevention and treatment of hypertension with no side effects, according to the studies.
Hypertension is a medical condition characterized by abnormally high blood pressure.
Acute high blood pressure is a risk of high blood pressure caused by sudden stress or physical activity in the short term that will eventually fall back to normal levels.
Chronic hypertension is a persistence of elevated high blood pressure which cannot be decreased without medication.
Chronic hypertension is one of the members of the cluster of conditions associated with metabolic syndrome and a major cause of cardiovascular disease.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
Some researchers suggested that hypertension may be caused by certain medical conditions, such as kidney disease, however, the cause of the syndrome is more likely as a result of an unhealthy lifestyle.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects.
Therefore, if you are currently taking medicine for the treatment of hypertension, please make sure you know all side effects for preventive measures.
Dr. Beilin LJ, at the University Department of Medicine, and West Australian Heart Research Institute in the examine the lifestyle risk of hypertension wrote, High salt intakes remain a major contributor to hypertension, especially when potassium intake is low. Smoking has a dominant effect in increasing cardiovascular risk in hypertensives ".
And, "Clustering of risk factors is often associated with clustering of unhealthy lifestyle characteristics and both are most prominent in lower socio-economic groups and in Developing Countries adopting a more sedentary lifestyle and Western diet patterns".
This statement clearly suggested that by making changes to lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.
Allicin is phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in onion and garlic.
On finding a natural compound for the prevention and treatment of high blood pressure, one of the major conditions associated with the onset of cardiovascular disease, researchers examined the antihypertensive phytochemical allicin isolated from garlic.
The study included nine patients with rather severe hypertension (diastolic blood pressure > or = 115 mm Hg).
Administrated garlic preparation including 1.3% allicin at a large dose (2400 mg) showed a sitting blood pressure fall of 7/16 (+/- 3/2 SD) mm Hg at peak effect approximately 5 hours after the dose.
From 5-14 hours after the dose, the preparation significantly decreased the diastolic blood pressure with no side effects.
Dr. McMahon FG, the lead scientist said, "Our results indicate that this garlic preparation can reduce blood pressure", after taking into account other factors.
Furthermore, in a total of 84 men with mild or moderate arterial hypertension, researchers compared the antihypertensive effects of time-released garlic powder tablets (Allicor) with that of regular garlic pills (Kwai)in a double-blind, placebo-controlled trial with an active control arm.
After an 8-week placebo treatment run-in phase, patients were randomized either to 600 mg Allicor (n=30) or to placebo (n=20) daily for 8 weeks In addition, in the open-label branch, patients received either 2400 mg Allicor daily (n=18) or 900 mg Kwai daily (n=16).
Allicor treatment at a dose of t600 mg daily showed a decrease of both systolic and diastolic blood pressures by 7.0 mm Hg (95% confidence interval (95% CI): 5.3-8.7) and 3.8 mm Hg (95% CI: 2.7-4.8), respectively.
However, Increasing the Allicor dosage to 2400 mg daily did not provide any additional benefit.
Treatment with Kwai exerted a similar effect in decreasing systolic blood pressure (5.4 mm Hg, 95% CI: 1.9-8.8) as those of Allicor, but no decrease in diastolic blood pressure.
The results clearly indicated that Allicor may process the prolonged action that was found in the Kwai treatment group.
Dr. Sobenin IA, the lead scientist wrote in the final report, "Time-released garlic powder tablets are more effective for the treatment of mild and moderate arterial hypertension than are regular garlic supplements".
Taken altogether, allicin, a bioactive compound processed with antihypertensive properties may be used for the prevention and treatment of high blood pressure, pending the validation of a large sample size and multicenter study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Can garlic lower blood pressure? A pilot study by McMahon FG, Vargas R.(PubMed)
(2) Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension by Sobenin IA, Andrianova IV, Fomchenkov IV, Gorchakova TV, Orekhov AN. (PubMed)
(3) Lifestyle and hypertension--an overview by Beilin LJ. (PubMed)
#Bromelain Improves the Immune System Against the Development of Cancers, Researchers Say
By Kyle J. Norton
The immune system is a network of cells, tissues, and organs that provide the body's defense against infectious organisms and pathogens.
The immune system can be classified into innate immunity and adaptive immunity
* Innate immunity comprised the cells and mechanisms is the process of the immune response against infection in a non-specific manner.
* Adaptive immunity or acquired immunity is the process to destroy pathogens or prevent their growth by a composed of highly specialized, systemic cells that have been causing a threat to the body in the past.
Diseases associated with the immune system can also be classified into underactive immunity and overactive immunity
* Underactive immunity also known as weakened immune function is a condition found mostly in people with chronic illness, the elderly, and children with immature immunity.
People with a weakened immune system are prone to infectious diseases.
* Overactive immunity is associated with autoimmune diseases, including celiac disease, diabetes mellitus type 1, Graves disease, and inflammatory bowel disease, caused by allergens induced by the immune system mistakenly attacking the body tissues.
In an inflammatory perspective, chronic inflammatory diseases are also caused by the immune system's failure in destroying all foreign invaders in the acute infection in a set period of time, leading to immune adaptation with the long-term production of pro-inflammatory cytokines.
Diseases associated with chronic inflammation include type II diabetes and cardiovascular disease.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a potential compound for the modulation of the immune system, researchers examined the effects on inflammation-related cytokines of two doses of bromelain in a single dose placebo-controlled 3 × crossovers randomized clinical trial.
Injection of bromelain demonstrated significant immune-modulatory effects on Th1 cell mediator interferon-gamma in response to antigenic stimulation, Th2-type cytokine IL-5 in the regulation of humoral immune responses to extracellular parasites and bacterial infection as well as the immunosuppressive cytokine interleukin (IL)-10.
In other words, bromelain has a general effect on the antigen-specific (T cell) compartment of the human immune system in the modulation of cellular responses of lymphocytes.
In order to obtain more information on bromelain immunomodulatory effects, researchers investigated the influence of bromelain and trypsin on the cytokine production and proliferation of peripheral blood mononuclear cells (PBMC) from patients with a classical cellular mediated autoimmune disorder, namely encephalomyelitis disseminate (ED) as well as from healthy controls.
The experiment was carried out with PBMC from patients with ED (n=12) and healthy controls (n=12) cultured for seven days at 37 degrees C under three different conditions: without antigen, with bromelain, and with trypsin (final concentrations 10-1000 microg/ml).
Compared to trypsin, PBMC from patients with ED and healthy controls showed a significantly increased proliferative response to bromelain (ED: 14053+/- 7585 CPM with bromelain vs. spontaneous proliferation of 430+/- 255 CPM; healthy controls.
Furthermore, bromelain modulated the immune expression by activating macrophages/monocytes and type 1 cell associated with the adaptive immunity process independently from the underlying disease.
Taken altogether, bromelain may be considered a remedy for the modulation of immune function, pending the confirmation of large sample size and multicenter study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain by Müller S1, März R, Schmolz M, Drewelow B, Eschmann K, Meiser P. (PubMed)
(2) In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans by Barth H1, Guseo A, Klein R. (PubMed)
The immune system is a network of cells, tissues, and organs that provide the body's defense against infectious organisms and pathogens.
The immune system can be classified into innate immunity and adaptive immunity
* Innate immunity comprised the cells and mechanisms is the process of the immune response against infection in a non-specific manner.
* Adaptive immunity or acquired immunity is the process to destroy pathogens or prevent their growth by a composed of highly specialized, systemic cells that have been causing a threat to the body in the past.
Diseases associated with the immune system can also be classified into underactive immunity and overactive immunity
* Underactive immunity also known as weakened immune function is a condition found mostly in people with chronic illness, the elderly, and children with immature immunity.
People with a weakened immune system are prone to infectious diseases.
* Overactive immunity is associated with autoimmune diseases, including celiac disease, diabetes mellitus type 1, Graves disease, and inflammatory bowel disease, caused by allergens induced by the immune system mistakenly attacking the body tissues.
In an inflammatory perspective, chronic inflammatory diseases are also caused by the immune system's failure in destroying all foreign invaders in the acute infection in a set period of time, leading to immune adaptation with the long-term production of pro-inflammatory cytokines.
Diseases associated with chronic inflammation include type II diabetes and cardiovascular disease.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a potential compound for the modulation of the immune system, researchers examined the effects on inflammation-related cytokines of two doses of bromelain in a single dose placebo-controlled 3 × crossovers randomized clinical trial.
Injection of bromelain demonstrated significant immune-modulatory effects on Th1 cell mediator interferon-gamma in response to antigenic stimulation, Th2-type cytokine IL-5 in the regulation of humoral immune responses to extracellular parasites and bacterial infection as well as the immunosuppressive cytokine interleukin (IL)-10.
In other words, bromelain has a general effect on the antigen-specific (T cell) compartment of the human immune system in the modulation of cellular responses of lymphocytes.
In order to obtain more information on bromelain immunomodulatory effects, researchers investigated the influence of bromelain and trypsin on the cytokine production and proliferation of peripheral blood mononuclear cells (PBMC) from patients with a classical cellular mediated autoimmune disorder, namely encephalomyelitis disseminate (ED) as well as from healthy controls.
The experiment was carried out with PBMC from patients with ED (n=12) and healthy controls (n=12) cultured for seven days at 37 degrees C under three different conditions: without antigen, with bromelain, and with trypsin (final concentrations 10-1000 microg/ml).
Compared to trypsin, PBMC from patients with ED and healthy controls showed a significantly increased proliferative response to bromelain (ED: 14053+/- 7585 CPM with bromelain vs. spontaneous proliferation of 430+/- 255 CPM; healthy controls.
Furthermore, bromelain modulated the immune expression by activating macrophages/monocytes and type 1 cell associated with the adaptive immunity process independently from the underlying disease.
Taken altogether, bromelain may be considered a remedy for the modulation of immune function, pending the confirmation of large sample size and multicenter study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain by Müller S1, März R, Schmolz M, Drewelow B, Eschmann K, Meiser P. (PubMed)
(2) In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans by Barth H1, Guseo A, Klein R. (PubMed)
#Phytochemical #Allylisothiocyanate Processes Anti-#ProstateCancer Properties in Vivos, Researchers Say
By Kyle J. Norton
Phytochemicals, the natural chemical constituent, protect the plants against diseases and form their outer's color.
Bioactive compound Allyl isothiocyanate has a profound and potential effect in reducing the risk and treatment of prostate cancer, some scientists suggested.
Allyl isothiocyanate is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in horseradish, mustard, wasabi, etc.
Prostate cancer is a condition in which the cells of the prostate have become cancerous, causing abnormal cell growth in the prostate tissue.
Most cases of prostate cancer start in the cell on the surface of the inner lining of the prostate tissue. At this stage, patients do not experience any symptoms.
However, as the tumor continued to grow, in the short distance in the future, it will suppress the nearby healthy tissue and nerve cells, leading to localized symptoms and severe pain.
At the advanced stage, most primary prostate cancer cells can travel a distance away to infect other healthy tissue and organ, leading to secondary cancer metastasis.
According to the statistic, In the US, approximately 164,690 new cases of prostate cancer were diagnosed and 29,430 will die from prostate cancer in 2018.
In fact, more than 2.9 million men in the United States who have been diagnosed with prostate cancer at some point are still alive today.
Early diagnosis is the key to survival in prostate cancer. The 5-year survival rate for most men with local or regional prostate cancer is nearly 100%. Ninety-eight percent (98%) are alive after 10 years.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.
The causes of prostate cancer are unknown. However, certain risk factors, epidemiologically are associated with an increased risk of the disease, including the increase in age, ethnicity, family history, genetic preposition, and poor diet.
Dr. Amir Bagheri, the lead author in the study "Dietary patterns and risk of prostate cancer: a factor analysis study in a sample of Iranian men" firmly suggested that a healthy dietary pattern was associated with a decreased risk of prostate cancer (highest versus lowest tertile OR:0.24; 95% CI: 0.07-0.81;trend p: 0.025). An unhealthy dietary pattern was related to increased risk of prostate cancer(highest versus lowest tertile OR:3.4; 95% CI: 1.09-10.32; trend p: 0.037).
Therefore, by a chance of the diet pattern which contains high fruits and vegetables and whole-grain and few saturated and trans fat, red meat, and processed foods, a healthy man can substantially decrease the risk of prostate cancer
On finding a natural ingredient or whole food for the prevention and treatment of prostate cancer, researchers evaluated the effects of allyl isothiocyanate (AITC), a constituent of cruciferous vegetables, against the growth of human prostate cancer xenografts in vivo.
Injection of 10 micromol AITC, three times per week (Monday, Wednesday, and Friday) beginning the day of tumor cell implantation significantly inhibited the growth of PC-3 xenograft.
On the 26 days after tumor cell implantation, the average tumor volume in control mice (1025 +/- 205 mm3) was approximately 1.7-fold higher compared with AITC-treated mice.
The histological analysis of tumors excised at the termination of the experiment, revealed a statistically significant increase in the number of apoptotic bodies with a concomitant decrease in cells undergoing mitosis in the tumors of AITC-treated mice compared with that of control mice.
The Western blot analysis indicated the injection of AITC inhibited the 70% of the levels of anti-apoptotic protein in the tumor lysate of AITC-treated mice compared with that of control mice.
The injection of AITC also exerted a statistically significant reduction in the expression of several proteins associated with the regulation of G2/M progression.
The finding suggested that AITC administration inhibits the growth of PC-3 xenografts in vivo by inducing apoptosis and reducing mitotic activity.
Futhermore, in order to understand the effect of dietary isothiocyanates (ITCs) in the protection against chemically induced cancers in laboratory animals, researchers examined the allyl isothiocyanate (AITC) anti-cancer activity in the cultured PC-3 (androgen-independent) and LNCaP (androgen-dependent) human prostate cancer cell.
Application of AITC inhibited all the tested cancer cell lines in a dose-dependent manner with an IC(50) of approximately 15-17 micro M.without affecting the normal prostate cancer cells.
The inhibition of the proliferation of PC-3 as well as LNCaP cells in the presence of AITC is correlated with the accumulation of cells in the G(2)/M phase and induction of apoptosis.
At 24 h treatment of PC-3 and LNCaP cells with 20 micro M, AITC scored a similar effect as that of the previous study by causing a significant decrease in the levels of proteins that regulate G(2)/M progression, and the levels of anti-apoptotic protein.
Taken altogether, Allyl isothiocyanate may be considered a dietary source for the prevention and treatment of prostate cancer with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits the growth of PC-3 human prostate cancer xenografts in vivo by Srivastava SK1, Xiao D, Lew KL, Hershberger P, Kokkinakis DM, Johnson CS, Trump DL, Singh SV. (PubMed)
(2) Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis by Xiao D1, Srivastava SK, Lew KL, Zeng Y, Hershberger P, Johnson CS, Trump DL, Singh SV. (PubMed)
(3) Dietary patterns and risk of prostate cancer: a factor analysis study in a sample of Iranian men by Amir Bagheri, Seyed Mostafa Nachvak, Mansour Rezaei, 3 Mozhgan Moravridzade, Mahmoudreza Moradi, 4 and Michael Nelson. (PMC)
Phytochemicals, the natural chemical constituent, protect the plants against diseases and form their outer's color.
Bioactive compound Allyl isothiocyanate has a profound and potential effect in reducing the risk and treatment of prostate cancer, some scientists suggested.
Allyl isothiocyanate is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in horseradish, mustard, wasabi, etc.
Prostate cancer is a condition in which the cells of the prostate have become cancerous, causing abnormal cell growth in the prostate tissue.
Most cases of prostate cancer start in the cell on the surface of the inner lining of the prostate tissue. At this stage, patients do not experience any symptoms.
However, as the tumor continued to grow, in the short distance in the future, it will suppress the nearby healthy tissue and nerve cells, leading to localized symptoms and severe pain.
At the advanced stage, most primary prostate cancer cells can travel a distance away to infect other healthy tissue and organ, leading to secondary cancer metastasis.
According to the statistic, In the US, approximately 164,690 new cases of prostate cancer were diagnosed and 29,430 will die from prostate cancer in 2018.
In fact, more than 2.9 million men in the United States who have been diagnosed with prostate cancer at some point are still alive today.
Early diagnosis is the key to survival in prostate cancer. The 5-year survival rate for most men with local or regional prostate cancer is nearly 100%. Ninety-eight percent (98%) are alive after 10 years.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.
The causes of prostate cancer are unknown. However, certain risk factors, epidemiologically are associated with an increased risk of the disease, including the increase in age, ethnicity, family history, genetic preposition, and poor diet.
Dr. Amir Bagheri, the lead author in the study "Dietary patterns and risk of prostate cancer: a factor analysis study in a sample of Iranian men" firmly suggested that a healthy dietary pattern was associated with a decreased risk of prostate cancer (highest versus lowest tertile OR:0.24; 95% CI: 0.07-0.81;trend p: 0.025). An unhealthy dietary pattern was related to increased risk of prostate cancer(highest versus lowest tertile OR:3.4; 95% CI: 1.09-10.32; trend p: 0.037).
Therefore, by a chance of the diet pattern which contains high fruits and vegetables and whole-grain and few saturated and trans fat, red meat, and processed foods, a healthy man can substantially decrease the risk of prostate cancer
On finding a natural ingredient or whole food for the prevention and treatment of prostate cancer, researchers evaluated the effects of allyl isothiocyanate (AITC), a constituent of cruciferous vegetables, against the growth of human prostate cancer xenografts in vivo.
Injection of 10 micromol AITC, three times per week (Monday, Wednesday, and Friday) beginning the day of tumor cell implantation significantly inhibited the growth of PC-3 xenograft.
On the 26 days after tumor cell implantation, the average tumor volume in control mice (1025 +/- 205 mm3) was approximately 1.7-fold higher compared with AITC-treated mice.
The histological analysis of tumors excised at the termination of the experiment, revealed a statistically significant increase in the number of apoptotic bodies with a concomitant decrease in cells undergoing mitosis in the tumors of AITC-treated mice compared with that of control mice.
The Western blot analysis indicated the injection of AITC inhibited the 70% of the levels of anti-apoptotic protein in the tumor lysate of AITC-treated mice compared with that of control mice.
The injection of AITC also exerted a statistically significant reduction in the expression of several proteins associated with the regulation of G2/M progression.
The finding suggested that AITC administration inhibits the growth of PC-3 xenografts in vivo by inducing apoptosis and reducing mitotic activity.
Futhermore, in order to understand the effect of dietary isothiocyanates (ITCs) in the protection against chemically induced cancers in laboratory animals, researchers examined the allyl isothiocyanate (AITC) anti-cancer activity in the cultured PC-3 (androgen-independent) and LNCaP (androgen-dependent) human prostate cancer cell.
Application of AITC inhibited all the tested cancer cell lines in a dose-dependent manner with an IC(50) of approximately 15-17 micro M.without affecting the normal prostate cancer cells.
The inhibition of the proliferation of PC-3 as well as LNCaP cells in the presence of AITC is correlated with the accumulation of cells in the G(2)/M phase and induction of apoptosis.
At 24 h treatment of PC-3 and LNCaP cells with 20 micro M, AITC scored a similar effect as that of the previous study by causing a significant decrease in the levels of proteins that regulate G(2)/M progression, and the levels of anti-apoptotic protein.
Taken altogether, Allyl isothiocyanate may be considered a dietary source for the prevention and treatment of prostate cancer with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits the growth of PC-3 human prostate cancer xenografts in vivo by Srivastava SK1, Xiao D, Lew KL, Hershberger P, Kokkinakis DM, Johnson CS, Trump DL, Singh SV. (PubMed)
(2) Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis by Xiao D1, Srivastava SK, Lew KL, Zeng Y, Hershberger P, Johnson CS, Trump DL, Singh SV. (PubMed)
(3) Dietary patterns and risk of prostate cancer: a factor analysis study in a sample of Iranian men by Amir Bagheri, Seyed Mostafa Nachvak, Mansour Rezaei, 3 Mozhgan Moravridzade, Mahmoudreza Moradi, 4 and Michael Nelson. (PMC)
#Healthyfood #Celery Shows A Significant Effect on High Blood Cholesterol, Researchers Say
By Kyle J. Norton
Scientists may have found a whole vegetable for the prevention and treatment of high blood cholesterol comparable to that of conventional medicine without inducing any side effects, according to studies.
High blood cholesterol is a medical condition of abnormally high levels of cholesterol in the blood.
There are 2 types of cholesterols in the human body, low-density lipoproteins, and high-density lipoproteins.
Low-density cholesterol plays an important role in building cell membranes, and inducing the production of bile, steroid hormones, and vitamin. However, long-term accumulation of cholesterol in the bloodstream not only impedes the blood flow of the arteries but also increases the risk of plaque building up on the arterial walls.
The high-density lipoprotein removes cholesterol from the blood and returns them to the liver. However, if the low-density lipoprotein in the bloodstream was found in high amounts, compared to high-density lipoprotein, then some bad cholesterols may be left in the arteries, causing the onset of high blood cholesterol.
The healthy ratio of blood cholesterol is lower than 4 (levels of low-density lipoprotein)/ 1(levels of high-density cholesterol).
What causes high blood cholesterol? Epidemiological studies suggested that a poor diet with rich in saturated and trans fat, red meat and processed foods, and few in fruits and vegetables are the most common risk factors that cause the onset of high blood cholesterol in the Western world.
According to the statistic, in Australia, over 1 million of the population have high blood cholesterol. The highest prevalent group is those between 55 to 64 year age group.
Sadly, one in five Australians aged 18 to 34 also has high total cholesterol.
Dr. Henry N. Ginsberg, the lead scientist in the cardiovascular disease team examining the risk of high blood cholesterol and dietary cholesterol in young and healthy men said, "Fasting plasma total cholesterol concentrations increased by 1.47 mg/dL (0.038 mmol/L) for every 100 mg dietary cholesterol added to the diet (P <.001). Low-density lipoprotein (LDL) cholesterol increased in parallel." and " increases in dietary cholesterol resulted in linear increases in fasting total and LDL cholesterol in young, healthy men".
These results suggested that short-term intake of high cholesterol diet does not have an effect on postprandial plasma lipids or an increased atherogenic potential of postprandial serum. In other words, high blood cholesterol is a condition caused by a long-term high-cholesterol diet that takes years to develop.
Celery is a species of Apium graveolens, belonging to the family Apiaceae. It is cultivated all around the globe as a vegetable. Celery can grow to 1/2 m tall with stalks (leaf on the top) arranged in a conical shape joined at a common base.
With an aim to find a natural ingredient or whole food which processes anti-high blood cholesterol activity with no side effects, researchers at the National University of Singapore looked into the antihyperlipidemic property of aqueous celery extract.
The study included 2 groups of Wistar rats fed a high-fat diet for eight weeks to induce hyperlipidemia. One group was supplemented with aqueous celery extract in the diet while the other group served as control.
At the end of the experiment, the treatment group exerted a significant reduction in the serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) concentrations, compared to the control.
The concentration of hepatic TG was significantly higher in the celery-treated group than in the control group. However, the hepatic triacylglycerol lipase (HL) activity was found to be significantly lower in the celery-treated rats observed for the hepatic microsomal P450 content which is an indication of individual hepatic clearance.
Surprisingly, researchers discovered that the aqueous extract of celery does not contain 3-n-butylphthalide (BuPh), a unique compound in celery. This result suggested that the efficacy of celery probably is associated with other major unknown compound compounds.
Furthermore, in examining other compounds that processed the anti-high blood cholesterol activity, researchers explored the antihyperlipidemic effect of ethanolic extract of seeds of Apium graveolens L. (celery) and its chloroform and aqueous basic fraction in olive oil-induced hyperlipidemic rats.
The antihyperlipidemic activity of Apium graveolens has been found in the previous study as effective as of the of standard drug Atorvastatin (50mg/kg).
The study included the ethanolic extract and its fractions administered orally at doses of 200 and 400 mg/kg body weight in rats followed by the Olive oil (5ml/kg oral dose) administered 30 min after treatment.
The ethanolic extract and its fractions of celery at a dose-dependently inhibited the total cholesterol (TC) triglycerides (TG), low-density lipoproteins (LDL) level, and significantly increased high-density lipoprotein (HDL) level.
The inhibition of high blood cholesterol was attributed to the major compounds terpenoid, tannin, alkaloid, glycoside, flavonoid, and sterols.
Taken altogether, celery containing high amounts of bioactive compounds may be considered a functional food for the prevention and treatment of high blood cholesterol with no side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effects of aqueous celery (Apium graveolens) extract on lipid parameters of rats fed a high fat diet by Tsi D1, Das NP, Tan BK.(PubMed)
(2) Effect of chloroform and an aqueous basic fraction of ethanolic extract from Apium graveolens L. in experimentally-induced hyperlipidemia in ratsm by Iyer D1, Patil UK(PubMed)
(3) Hypolipidemic and antioxidant activity of mountain celery (Cryptotaenia japonica Hassk) seed essential oils by Cheng MC1, Lin LY, Yu TH, Peng RY.(PubMed)
(4) The mechanism underlying the hypocholesterolaemic activity of aqueous celery extract, its butanol and aqueous fractions in genetically hypercholesterolaemic RICO rats by Tsi D1, Tan BK.(PubMed)
(5) Effects of celery extract and 3-N-butylphthalide on lipid levels in genetically hypercholesterolaemic (RICO) rats by Tsi D1, Tan BK.(PubMed)
(6) A Dose-Response Study of the Effects of Dietary Cholesterol on Fasting and Postprandial Lipid and Lipoprotein Metabolism in Healthy Young Men by Henry N. Ginsberg, Wahida Karmally, Maliha Siddiqui, Steve Holleran, Alan R. Tall, Steven C. Rumsey, Richard J. Deckelbaum, William S. Blaner, and Rajasekhar Ramakrishnan. (PMC)
Scientists may have found a whole vegetable for the prevention and treatment of high blood cholesterol comparable to that of conventional medicine without inducing any side effects, according to studies.
High blood cholesterol is a medical condition of abnormally high levels of cholesterol in the blood.
There are 2 types of cholesterols in the human body, low-density lipoproteins, and high-density lipoproteins.
Low-density cholesterol plays an important role in building cell membranes, and inducing the production of bile, steroid hormones, and vitamin. However, long-term accumulation of cholesterol in the bloodstream not only impedes the blood flow of the arteries but also increases the risk of plaque building up on the arterial walls.
The high-density lipoprotein removes cholesterol from the blood and returns them to the liver. However, if the low-density lipoprotein in the bloodstream was found in high amounts, compared to high-density lipoprotein, then some bad cholesterols may be left in the arteries, causing the onset of high blood cholesterol.
The healthy ratio of blood cholesterol is lower than 4 (levels of low-density lipoprotein)/ 1(levels of high-density cholesterol).
What causes high blood cholesterol? Epidemiological studies suggested that a poor diet with rich in saturated and trans fat, red meat and processed foods, and few in fruits and vegetables are the most common risk factors that cause the onset of high blood cholesterol in the Western world.
According to the statistic, in Australia, over 1 million of the population have high blood cholesterol. The highest prevalent group is those between 55 to 64 year age group.
Sadly, one in five Australians aged 18 to 34 also has high total cholesterol.
Dr. Henry N. Ginsberg, the lead scientist in the cardiovascular disease team examining the risk of high blood cholesterol and dietary cholesterol in young and healthy men said, "Fasting plasma total cholesterol concentrations increased by 1.47 mg/dL (0.038 mmol/L) for every 100 mg dietary cholesterol added to the diet (P <.001). Low-density lipoprotein (LDL) cholesterol increased in parallel." and " increases in dietary cholesterol resulted in linear increases in fasting total and LDL cholesterol in young, healthy men".
These results suggested that short-term intake of high cholesterol diet does not have an effect on postprandial plasma lipids or an increased atherogenic potential of postprandial serum. In other words, high blood cholesterol is a condition caused by a long-term high-cholesterol diet that takes years to develop.
Celery is a species of Apium graveolens, belonging to the family Apiaceae. It is cultivated all around the globe as a vegetable. Celery can grow to 1/2 m tall with stalks (leaf on the top) arranged in a conical shape joined at a common base.
With an aim to find a natural ingredient or whole food which processes anti-high blood cholesterol activity with no side effects, researchers at the National University of Singapore looked into the antihyperlipidemic property of aqueous celery extract.
The study included 2 groups of Wistar rats fed a high-fat diet for eight weeks to induce hyperlipidemia. One group was supplemented with aqueous celery extract in the diet while the other group served as control.
At the end of the experiment, the treatment group exerted a significant reduction in the serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) concentrations, compared to the control.
The concentration of hepatic TG was significantly higher in the celery-treated group than in the control group. However, the hepatic triacylglycerol lipase (HL) activity was found to be significantly lower in the celery-treated rats observed for the hepatic microsomal P450 content which is an indication of individual hepatic clearance.
Surprisingly, researchers discovered that the aqueous extract of celery does not contain 3-n-butylphthalide (BuPh), a unique compound in celery. This result suggested that the efficacy of celery probably is associated with other major unknown compound compounds.
Furthermore, in examining other compounds that processed the anti-high blood cholesterol activity, researchers explored the antihyperlipidemic effect of ethanolic extract of seeds of Apium graveolens L. (celery) and its chloroform and aqueous basic fraction in olive oil-induced hyperlipidemic rats.
The antihyperlipidemic activity of Apium graveolens has been found in the previous study as effective as of the of standard drug Atorvastatin (50mg/kg).
The study included the ethanolic extract and its fractions administered orally at doses of 200 and 400 mg/kg body weight in rats followed by the Olive oil (5ml/kg oral dose) administered 30 min after treatment.
The ethanolic extract and its fractions of celery at a dose-dependently inhibited the total cholesterol (TC) triglycerides (TG), low-density lipoproteins (LDL) level, and significantly increased high-density lipoprotein (HDL) level.
The inhibition of high blood cholesterol was attributed to the major compounds terpenoid, tannin, alkaloid, glycoside, flavonoid, and sterols.
Taken altogether, celery containing high amounts of bioactive compounds may be considered a functional food for the prevention and treatment of high blood cholesterol with no side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effects of aqueous celery (Apium graveolens) extract on lipid parameters of rats fed a high fat diet by Tsi D1, Das NP, Tan BK.(PubMed)
(2) Effect of chloroform and an aqueous basic fraction of ethanolic extract from Apium graveolens L. in experimentally-induced hyperlipidemia in ratsm by Iyer D1, Patil UK(PubMed)
(3) Hypolipidemic and antioxidant activity of mountain celery (Cryptotaenia japonica Hassk) seed essential oils by Cheng MC1, Lin LY, Yu TH, Peng RY.(PubMed)
(4) The mechanism underlying the hypocholesterolaemic activity of aqueous celery extract, its butanol and aqueous fractions in genetically hypercholesterolaemic RICO rats by Tsi D1, Tan BK.(PubMed)
(5) Effects of celery extract and 3-N-butylphthalide on lipid levels in genetically hypercholesterolaemic (RICO) rats by Tsi D1, Tan BK.(PubMed)
(6) A Dose-Response Study of the Effects of Dietary Cholesterol on Fasting and Postprandial Lipid and Lipoprotein Metabolism in Healthy Young Men by Henry N. Ginsberg, Wahida Karmally, Maliha Siddiqui, Steve Holleran, Alan R. Tall, Steven C. Rumsey, Richard J. Deckelbaum, William S. Blaner, and Rajasekhar Ramakrishnan. (PMC)
#Healthyfood #CruciferousVegetables Process Anti #BreastCancer Activties, Scientists Say
By Kyle J. Norton
Scientists may have found a delicious whole food that has potential in the prevention and treatment of breast cancer, some studies suggested.
Breast cancer (malignant breast neoplasm) is a chronic disease characterized by abnormal cell growth in either the tissues of the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.
There are also rare cases that breast cancer starts in other areas of the breast.
According to the statistic, in 2010, over 250,000 new cases of breast cancer were diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
As of today, the exact causes of breast cancer are still unknown. Researchers believed that
genetic mutation inherited from the parents and an unhealthy diet and lifestyle are the major factors that facilitate the early onset of the disease.
However, dietary factors that contribute to chronic low-grade metabolic acidosis have been linked to breast cancer risk, and probably are associated with the diet-dependent acid load in the risk of breast cancer.
Dr. Park YM, the lead scientist in the study "Higher diet-dependent acid load, is associated with risk of breast cancer: Findings from the Sister Study" in the differentiation of The Potential Renal Acid Load (PRAL) score used to estimate the diet-dependent acid load, said, "Since PRAL scores are positively correlated with meat consumption and negatively correlated with fruit and vegetable intake, results also suggest that diets high in fruits and vegetables and low in meat may be protective against hormone receptor-negative breast cancer".
These results suggested women who follow the typical Western diet are associated with a higher risk of breast cancer, development.
Many other factors like pesticides used in agriculture or the exposure to chemical substances, electromagnetic pollution, environmental pollution, or cosmic radiation, as well as the use of cell phones, cosmetics, and bras, even television viewing time,
Dr. Max Dieterich, the lead author in the concerns of an unhealthy lifestyle in risk of breast cancer, wrote, "Appropriate education programs addressing lifestyle changes are crucial in terms of preventing BC. These programs should be carried out by experts, begin during childhood, and should contain information about the importance of a healthy dietary pattern, the avoidance of adult weight gain, physical activity, and the renunciation of alcohol and tobacco".
These proposals suggested, women who change from the Western diet pattern and unhealthy lifestyle to a healthy diet pattern and lifestyle are associated with substantially reduced risk of breast cancer, compared to those who do not.
Cruciferous vegetables are a group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli, etc.
Its chemical constituents include glucosinolates, dithiolthiones, indoles, glucoraphanin, s-methyl cysteine sulfoxide, isothiocyanates, indole-3-carbinol, etc.
In the study to examine the anti-breast cancer effect of the organic isothiocyanates (ITCs), the dietary components present in cruciferous vegetables in human breast cancer MCF-7 and human mammary epithelium MCF-12A cell lines, as well as in a second human epithelial cell line, human kidney HK-2 cells, researchers at the University at Buffalo found that
* Benzyls isothiocyanate (BITC), beta-phenethyl isothiocyanate (PEITC), the derivative components of ITC can inhibit the growth of human breast cancer cells as well as human mammary epithelial cells at concentrations similar to those of the chemotherapeutic drug DNM.
* Sulforaphane and 1-naphthyl isothiocyanate (NITC) exert the cytotoxicity effect against MCF-7 and human mammary epithelium MCF-12A at higher IC50 values compared to BEITC and BITC.
* The effect of these ITCs on cell growth may contribute to the cancer chemopreventive properties of ITCs by suppressing the growth of preclinical tumors.
Furthermore, in the assessment of Cruciferous vegetables' isothiocyanates (ITCs) in the risk of breast cancer, researchers at the Roswell Park Cancer Institute launched an investigation to evaluate the associations between consumption of cruciferous vegetables, sources of ITCs, and breast cancer risk, and potential modification of relations by GSTM1 and GSTT1 genotypes.
Participants in the study include cases of 740 Caucasian women with incident breast cancer identified from all major hospitals in Erie and Niagara counties and 810 controls matched to cases by age and county.
Consumption of cruciferous vegetables, particularly broccoli, was marginally inversely associated with breast cancer risk in premenopausal women.
Associations were weaker or null among postmenopausal women. No significant effects of GST genotype on risk were observed in either the menopausal group.
The finding suggested cruciferous vegetables intake regularly and daily may play an important role in decreasing the risk of premenopausal breast cancer.
Interestingly, in the study of cruciferous vegetable intake and the GSTP1 Ile(105)Val genetic polymorphism on breast cancer risk, including 3035 cases and 3037 population controls who were participating in the Shanghai Breast Cancer Study and for whom diet and genetic data were complete (87% of cases and 85% of controls), researchers found that
* Cruciferous vegetable intake consistent with high isothiocyanate exposure may reduce breast cancer risk.
* Cruciferous vegetable intake also may ameliorate the effects of the GSTP1 genotype in contribution to the risk of breast cancer.
Taken altogether, regular and daily intake of cruciferous vegetables is associated with a decreasing risk of breast cancer, particularly, in women with the GSTP1 genotype.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Dietary organic isothiocyanates are cytotoxic in human breast cancerMCF-7 and mammary epithelial MCF-12A cell lines by Tseng E, Scott-Ramsay EA, Morris ME. (PubMed)
(2) Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype by Ambrosone CB, McCann SE, Freudenheim JL, Marshall JR, Zhang Y, Shields PG. (PubMed)
(3) Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk by Lee SA, Fowke JH, Lu W, Ye C, Zheng Y, Cai Q, Gu K, Gao YT, Shu XO, Zheng W.(PubMed)
(4) Higher diet-dependent acid load is associated with risk of breast cancer: Findings from the Sister Study by Park YM1, Steck SE2,3, Fung TT4,5, Merchant AT3, Hodgson ME6, Keller JA7, Sandler DP1. (PubMed)
Scientists may have found a delicious whole food that has potential in the prevention and treatment of breast cancer, some studies suggested.
Breast cancer (malignant breast neoplasm) is a chronic disease characterized by abnormal cell growth in either the tissues of the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.
There are also rare cases that breast cancer starts in other areas of the breast.
According to the statistic, in 2010, over 250,000 new cases of breast cancer were diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of a woman is 1/8.
As of today, the exact causes of breast cancer are still unknown. Researchers believed that
genetic mutation inherited from the parents and an unhealthy diet and lifestyle are the major factors that facilitate the early onset of the disease.
However, dietary factors that contribute to chronic low-grade metabolic acidosis have been linked to breast cancer risk, and probably are associated with the diet-dependent acid load in the risk of breast cancer.
Dr. Park YM, the lead scientist in the study "Higher diet-dependent acid load, is associated with risk of breast cancer: Findings from the Sister Study" in the differentiation of The Potential Renal Acid Load (PRAL) score used to estimate the diet-dependent acid load, said, "Since PRAL scores are positively correlated with meat consumption and negatively correlated with fruit and vegetable intake, results also suggest that diets high in fruits and vegetables and low in meat may be protective against hormone receptor-negative breast cancer".
These results suggested women who follow the typical Western diet are associated with a higher risk of breast cancer, development.
Many other factors like pesticides used in agriculture or the exposure to chemical substances, electromagnetic pollution, environmental pollution, or cosmic radiation, as well as the use of cell phones, cosmetics, and bras, even television viewing time,
Dr. Max Dieterich, the lead author in the concerns of an unhealthy lifestyle in risk of breast cancer, wrote, "Appropriate education programs addressing lifestyle changes are crucial in terms of preventing BC. These programs should be carried out by experts, begin during childhood, and should contain information about the importance of a healthy dietary pattern, the avoidance of adult weight gain, physical activity, and the renunciation of alcohol and tobacco".
These proposals suggested, women who change from the Western diet pattern and unhealthy lifestyle to a healthy diet pattern and lifestyle are associated with substantially reduced risk of breast cancer, compared to those who do not.
Cruciferous vegetables are a group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli, etc.
Its chemical constituents include glucosinolates, dithiolthiones, indoles, glucoraphanin, s-methyl cysteine sulfoxide, isothiocyanates, indole-3-carbinol, etc.
In the study to examine the anti-breast cancer effect of the organic isothiocyanates (ITCs), the dietary components present in cruciferous vegetables in human breast cancer MCF-7 and human mammary epithelium MCF-12A cell lines, as well as in a second human epithelial cell line, human kidney HK-2 cells, researchers at the University at Buffalo found that
* Benzyls isothiocyanate (BITC), beta-phenethyl isothiocyanate (PEITC), the derivative components of ITC can inhibit the growth of human breast cancer cells as well as human mammary epithelial cells at concentrations similar to those of the chemotherapeutic drug DNM.
* Sulforaphane and 1-naphthyl isothiocyanate (NITC) exert the cytotoxicity effect against MCF-7 and human mammary epithelium MCF-12A at higher IC50 values compared to BEITC and BITC.
* The effect of these ITCs on cell growth may contribute to the cancer chemopreventive properties of ITCs by suppressing the growth of preclinical tumors.
Furthermore, in the assessment of Cruciferous vegetables' isothiocyanates (ITCs) in the risk of breast cancer, researchers at the Roswell Park Cancer Institute launched an investigation to evaluate the associations between consumption of cruciferous vegetables, sources of ITCs, and breast cancer risk, and potential modification of relations by GSTM1 and GSTT1 genotypes.
Participants in the study include cases of 740 Caucasian women with incident breast cancer identified from all major hospitals in Erie and Niagara counties and 810 controls matched to cases by age and county.
Consumption of cruciferous vegetables, particularly broccoli, was marginally inversely associated with breast cancer risk in premenopausal women.
Associations were weaker or null among postmenopausal women. No significant effects of GST genotype on risk were observed in either the menopausal group.
The finding suggested cruciferous vegetables intake regularly and daily may play an important role in decreasing the risk of premenopausal breast cancer.
Interestingly, in the study of cruciferous vegetable intake and the GSTP1 Ile(105)Val genetic polymorphism on breast cancer risk, including 3035 cases and 3037 population controls who were participating in the Shanghai Breast Cancer Study and for whom diet and genetic data were complete (87% of cases and 85% of controls), researchers found that
* Cruciferous vegetable intake consistent with high isothiocyanate exposure may reduce breast cancer risk.
* Cruciferous vegetable intake also may ameliorate the effects of the GSTP1 genotype in contribution to the risk of breast cancer.
Taken altogether, regular and daily intake of cruciferous vegetables is associated with a decreasing risk of breast cancer, particularly, in women with the GSTP1 genotype.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Dietary organic isothiocyanates are cytotoxic in human breast cancerMCF-7 and mammary epithelial MCF-12A cell lines by Tseng E, Scott-Ramsay EA, Morris ME. (PubMed)
(2) Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype by Ambrosone CB, McCann SE, Freudenheim JL, Marshall JR, Zhang Y, Shields PG. (PubMed)
(3) Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk by Lee SA, Fowke JH, Lu W, Ye C, Zheng Y, Cai Q, Gu K, Gao YT, Shu XO, Zheng W.(PubMed)
(4) Higher diet-dependent acid load is associated with risk of breast cancer: Findings from the Sister Study by Park YM1, Steck SE2,3, Fung TT4,5, Merchant AT3, Hodgson ME6, Keller JA7, Sandler DP1. (PubMed)
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