By Kyle J. Norton
Asparagus is a flowering plant belonging to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, northwest Germany, northern Africa, and western Asia, used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.
Asparagus may be the next potential whole food medicine in the inhibited expression of pro-inflammatory cytokines in inducing fever, pain, and swelling in the affected locations,...
Inflammation is a natural expression by the immune system in the induction of white blood cells to protect our body against infection with foreign invasion.
According to the Korea Institute of Oriental Medicine, in an investigation of chronic skin inflammation, using 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced mouse ear edema, administration at 200mg/kg (i.p.) of ethanolic extract from Asparagus cochinchinensis Merrill (ACE)expressed strong anti-inflammatory effect through inhibited topical edema in the mouse ear, and substantial reductions in skin thickness and tissue weight, inflammatory cytokine production,.....
Dr. Lee DY, the lead author in the study said, "ACE is an effective anti-inflammatory agent in murine phorbol ester-induced dermatitis" and " the compound may have therapeutic potential in a variety of immune-related cutaneous diseases."
The study of pharmacological properties of Asparagus racemosus root extracts (AR), also addressed the potential use of extract formulation for topical and/or transdermal drugs to provide anti-inflammatory activity, due to its significant attenuation involved in systemic inflammation, without causing toxicity to experiment monocytic leukemia cell line THP-1.
Furthermore, the extract from asparagus also exerts an inhibitory effect on pro-inflammatory cytokines, namely interleukin 1β and tumor necrosis factor α, and on the production of nitric oxide in free radical-mediated lipid oxidation stimulated by lipopolysaccharide in regulated immune response in vitro.
Some researchers insisted the properties of anti-inflammation of asparagus may also be due to the presence of phytochemical saponin contents in comparison to the group treated with crude saponin extracts in the rat paw-edema and the control group.
Taking it all together, Asparagus may have a potential anti-inflammatory effect in reduced risk and treatment of chronic inflammatory diseases. The efficacy is not due to a single ingredient in the food but the whole food.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Anti-inflammatory effects of Asparagus cochinchinensis extract in acute and chronic cutaneous inflammation by Lee DY1, Choo BK, Yoon T, Cheon MS, Lee HW, Lee AY, Kim HK. (PubMed)
(2) Anti-inflammatory activity of liposomes of Asparagus racemosus root extracts prepared by various methods by Plangsombat N1, Rungsardthong K2, Kongkaneramit L3, Waranuch N4, Sarisuta N5.(PubMed)
(3) Effects of Chlorophytum arundinaceum, Asparagus adscendens and Asparagusracemosus on pro-inflammatory cytokine and corticosterone levels produced by stress by Kanwar AS1, Bhutani KK.(PubMed)
(4) Anti-inflammatory activity of crude saponin extracts from five Nigerian medicinal plants by Hassan HS1, Sule MI, Musa AM, Musa KY, Abubakar MS, Hassan AS.(PubMed)
Tuesday, 6 June 2023
#Herbal #Turmeric Decreases the Risk of #HeadandNeckCancers In Vitro and Vivo, According to Studies
By Kyle J. Norton
Cancer is a group of medical diseases characterized by cell growth irregularly in the organ tissue caused by DNA alternation.
Head and neck cancer (HNC) is a group of cancers located in the mouth, nose, throat, larynx, sinuses, or salivary glands.
According to the statistics, head and neck cancer accounts for about 4% of all cancers in the US. In 2019, approximately 65,410 Americans including 48,000 men and 17,410 women will develop head and neck cancer.
The overall survival rate of 5 years after diagnosis is 62%.
The use of tobacco products and excessive alcohol consumption are considered the most prevalent factor associated with the increased risk of the disease.
Additionally, viral infections including human papillomavirus (HPV) infection (for oropharyngeal cancer), and Epstein-Barr virus (EBV) infection (for nasopharyngeal cancer) are also found in some patients with HNC.
Epidemiologically, the overall incidence of HNC is decreasing in the US, particularly in those of the younger age group. However, the incidence of HPV-related cancers of the oropharynx is increased at an alarming rate.
Dr. Moustafa Mourad,, the lead scientist wrote, "The overall incidence of HNC is decreasing in the United States. However, there is an increasing incidence of HPV-related cancers of the oropharynx. Meaningful differences in cancer incidence and rate of change exist between men and women".
In the explanation of such an increase, the study suggested, "The recent increase in HPV-related cancer could be due to increased rates of oral HPV exposure because markers of high-risk sexual behavior such as younger ages of sexual debut, premarital sex, the average number of lifetime partners, and the practice of oral sex have increased among recent birth cohorts in the United States".
In other words, the risk of HPV-related HNC is also depending on the sexual behavior of individuals.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential compound for the treatment of head and neck cancers. researchers the anticancer activity of a novel oral agent, curcumin on FaDu and Cal27 cell lines.
According to the tested analysis, curcumin inhibited growth and induced apoptosis of the FaDu and Cal27 cell lines associated with the inhibition of the migration of head and neck cancers (HNSCC) and blocking the tumor angiogenetic activity.
Furthermore, curcumin also induced cancer cell death by activating the intrinsic apoptotic pathway (caspase-9) and extrinsic apoptotic pathway (caspase-8).
More precisely, the anti-HNSCC efficacy of curcumin was attributed to the activation of the pathway and nuclear factors associated with DNA damage.
In vivo, the injection of curcumin increased gene expression of SIRT1 in the regulation of cellular biological function in a xenograft mouse model.
In other words, by targeting the gene SIRT1 that promotes the survival of aging cells and increases cancer risk, curcumin not only can increase the chemo drug efficacy but also reduced the risk of side effects.
Taken altogether, turmeric-processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of head and neck cancers, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin as therapeutics for the treatment of head and neck squamous cell carcinoma by activating SIRT1 by Hu A1, Huang JJ2, Li RL3, Lu ZY3, Duan JL3, Xu WH1, Chen XP1, Fan JP. (PubMed)
(2) Synthetic curcumin analog UBS109 inhibits the growth of head and necksquamous cell carcinoma xenografts by Zhu S, Moore TW, Morii N, Howard RB, Culver D, Arrendale RF, Reddy P, Evers TJ, Zhang H, Sica G, Chen ZG, Sun A, Fu H, Khuri FR, Shin DM, Snyder JP, Shoji M. (PubMed)
(3) Epidemiological Trends of Head and Neck Cancer in the United States: A SEER Population Study by Moustafa Mourad, MD,* Thomas Jetmore, MD,† Ameya A. Jategaonkar, MD,‡ Sami Moubayed, MD,§ Erin Moshier, PhD,║ and Mark L. Urken, MD. (PMC)
Cancer is a group of medical diseases characterized by cell growth irregularly in the organ tissue caused by DNA alternation.
Head and neck cancer (HNC) is a group of cancers located in the mouth, nose, throat, larynx, sinuses, or salivary glands.
According to the statistics, head and neck cancer accounts for about 4% of all cancers in the US. In 2019, approximately 65,410 Americans including 48,000 men and 17,410 women will develop head and neck cancer.
The overall survival rate of 5 years after diagnosis is 62%.
The use of tobacco products and excessive alcohol consumption are considered the most prevalent factor associated with the increased risk of the disease.
Additionally, viral infections including human papillomavirus (HPV) infection (for oropharyngeal cancer), and Epstein-Barr virus (EBV) infection (for nasopharyngeal cancer) are also found in some patients with HNC.
Epidemiologically, the overall incidence of HNC is decreasing in the US, particularly in those of the younger age group. However, the incidence of HPV-related cancers of the oropharynx is increased at an alarming rate.
Dr. Moustafa Mourad,, the lead scientist wrote, "The overall incidence of HNC is decreasing in the United States. However, there is an increasing incidence of HPV-related cancers of the oropharynx. Meaningful differences in cancer incidence and rate of change exist between men and women".
In the explanation of such an increase, the study suggested, "The recent increase in HPV-related cancer could be due to increased rates of oral HPV exposure because markers of high-risk sexual behavior such as younger ages of sexual debut, premarital sex, the average number of lifetime partners, and the practice of oral sex have increased among recent birth cohorts in the United States".
In other words, the risk of HPV-related HNC is also depending on the sexual behavior of individuals.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential compound for the treatment of head and neck cancers. researchers the anticancer activity of a novel oral agent, curcumin on FaDu and Cal27 cell lines.
According to the tested analysis, curcumin inhibited growth and induced apoptosis of the FaDu and Cal27 cell lines associated with the inhibition of the migration of head and neck cancers (HNSCC) and blocking the tumor angiogenetic activity.
Furthermore, curcumin also induced cancer cell death by activating the intrinsic apoptotic pathway (caspase-9) and extrinsic apoptotic pathway (caspase-8).
More precisely, the anti-HNSCC efficacy of curcumin was attributed to the activation of the pathway and nuclear factors associated with DNA damage.
In vivo, the injection of curcumin increased gene expression of SIRT1 in the regulation of cellular biological function in a xenograft mouse model.
In other words, by targeting the gene SIRT1 that promotes the survival of aging cells and increases cancer risk, curcumin not only can increase the chemo drug efficacy but also reduced the risk of side effects.
Taken altogether, turmeric-processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of head and neck cancers, pending the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin as therapeutics for the treatment of head and neck squamous cell carcinoma by activating SIRT1 by Hu A1, Huang JJ2, Li RL3, Lu ZY3, Duan JL3, Xu WH1, Chen XP1, Fan JP. (PubMed)
(2) Synthetic curcumin analog UBS109 inhibits the growth of head and necksquamous cell carcinoma xenografts by Zhu S, Moore TW, Morii N, Howard RB, Culver D, Arrendale RF, Reddy P, Evers TJ, Zhang H, Sica G, Chen ZG, Sun A, Fu H, Khuri FR, Shin DM, Snyder JP, Shoji M. (PubMed)
(3) Epidemiological Trends of Head and Neck Cancer in the United States: A SEER Population Study by Moustafa Mourad, MD,* Thomas Jetmore, MD,† Ameya A. Jategaonkar, MD,‡ Sami Moubayed, MD,§ Erin Moshier, PhD,║ and Mark L. Urken, MD. (PMC)
#Antioxidant #Betanin Found in Beetroot Extracts Gobble Up Breast Cancer Cells in Vitro, Researchers Suggest
By Kyle J. Norton
Breast cancer is a chronic medical condition characterized by cell growth irregularly in the breast tissues due to DNA alternation.
Most cases of breast cancer begin in the cell on the surface of the inner lining of the breast tissues before penetrating into the deeper layers.
According to the statistics, in the US the lifetime of breast cancer in women is 1/8. In other words, if you are a woman, your risk of breast cancer development during your lifetime is 12.5%.
According to the prediction using historical data, in 2019, approximately 268,600 new cases of invasive breast cancer are expected to be diagnosed in women in the U.S., along with 62,930 new cases of non-invasive (in situ) breast cancer.
The exact causes of breast cancer are not identified. However, according to epidemiological studies, certain conditions may increase the risk of the disease such as being overweight, diet, inactivity, excessive alcohol consumption, smoking, and exposure to xenoestrogen.
Some researchers suggested that the discovery of oral contraceptive pills over the past few decades may correlate to the rise of breast cancer.
In other words, if you currently use an oral contraceptive, you are at a higher risk of the disease onset.
Dr. Kathleen E. Malone in the examined breast cancer risk in women who use oral contraceptives wrote, "Breast cancer incidence in Western countries is relatively high and apparently is increasing. That breast cancer appears to be influenced by other hormonally mediated factors leads to the hypothesis that the high rate of exposure to oral contraceptives among American women may also be associated with this increase".
And, "an increasing number of studies have appeared that suggest an elevated risk in relation to some aspects of oral contractive use".
Betanin is Phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to find a potential ingredient in plant phytochemicals for the treatment of breast cancer without inducing adverse effects compared to those of conventional medicine, researchers examined the extracts containing betanin and its stereoisomer isobetanin, which belongs to the betalain group of highly bioavailable antioxidants.
The study involved the analysis of the cytotoxicity of applying betanin-enriched extract then characterized on cancer and normal cells.
Betanin/isobetanin concentrate significantly decreased cancer cell proliferation and viability of MCF-7-treated cells, by inducing the production of proteins associated with proapoptosis and genes associated with tumor suppression.
Observation of the increased alternation of the mitochondrial membrane potential suggested that the extracts cause cancer cell death by both intrinsic and extrinsic apoptotic pathways.
The death of MCF-7-treated cells is also attributed to betanin/isobetanin induced autophagy.
Interestingly, the injection of betanin-enriched extract showed no obvious effect on normal cell lines.
Dr. Nowacki L, the lead scientist said, "the betanin/isobetanin mix as a therapeutic anticancer compound, alone or in combination with classical chemotherapeutic drugs, especially in functional p53 tumors".
In other words, betanin/isobetanin mix extracts processed anti-breast cancer cell proliferation by inducing cell death without affecting the integrity and viability of the normal breast cells.
In the analysis of the FDA-approved red food color E162, used in suppressing the development of multi-organ tumors in experimental animals, researchers compared the cytotoxic effect of the red beetroot extract with an anticancer drug, doxorubicin (Adriamycin) in the estrogen receptor-positive human breast cancer cells (MCF-7).
Beetroot extract exerted a significantly lower cancer cell inhibition compared to that doxorubicin.
The findings suggested that betanin, the major betacyanin constituent, may play an important role in the cytotoxicity exhibited by the red beetroot extract, according to the study.
Taken altogether, betanin used alone or combined with other phytochemicals may be considered supplements for the prevention and treatment of breast cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of betanin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betanin-Enriched Red Beetroot (Beta vulgaris L.) Extract Induces Apoptosis and Autophagic Cell Death in MCF-7 Cells by Nowacki L1,2, Vigneron P2, Rotellini L2, Cazzola H1, Merlier F1, Prost E1, Ralanairina R3, Gadonna JP3, Rossi C1, Vayssade M2. (PubMed)
(2) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancercell lines by Kapadia GJ1, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
(3) Oral Contraceptives and Breast Cancer: A Review of the Epidemiological Evidence with an Emphasis on Younger Women by Kathleen E. Malone. (NCBI)
Breast cancer is a chronic medical condition characterized by cell growth irregularly in the breast tissues due to DNA alternation.
Most cases of breast cancer begin in the cell on the surface of the inner lining of the breast tissues before penetrating into the deeper layers.
According to the statistics, in the US the lifetime of breast cancer in women is 1/8. In other words, if you are a woman, your risk of breast cancer development during your lifetime is 12.5%.
According to the prediction using historical data, in 2019, approximately 268,600 new cases of invasive breast cancer are expected to be diagnosed in women in the U.S., along with 62,930 new cases of non-invasive (in situ) breast cancer.
The exact causes of breast cancer are not identified. However, according to epidemiological studies, certain conditions may increase the risk of the disease such as being overweight, diet, inactivity, excessive alcohol consumption, smoking, and exposure to xenoestrogen.
Some researchers suggested that the discovery of oral contraceptive pills over the past few decades may correlate to the rise of breast cancer.
In other words, if you currently use an oral contraceptive, you are at a higher risk of the disease onset.
Dr. Kathleen E. Malone in the examined breast cancer risk in women who use oral contraceptives wrote, "Breast cancer incidence in Western countries is relatively high and apparently is increasing. That breast cancer appears to be influenced by other hormonally mediated factors leads to the hypothesis that the high rate of exposure to oral contraceptives among American women may also be associated with this increase".
And, "an increasing number of studies have appeared that suggest an elevated risk in relation to some aspects of oral contractive use".
Betanin is Phytochemical in the class of red and yellow indole-derived pigments of Betacyanins, belonging to the group of Betalains, found abundantly in beets, chard, etc.
With an aim to find a potential ingredient in plant phytochemicals for the treatment of breast cancer without inducing adverse effects compared to those of conventional medicine, researchers examined the extracts containing betanin and its stereoisomer isobetanin, which belongs to the betalain group of highly bioavailable antioxidants.
The study involved the analysis of the cytotoxicity of applying betanin-enriched extract then characterized on cancer and normal cells.
Betanin/isobetanin concentrate significantly decreased cancer cell proliferation and viability of MCF-7-treated cells, by inducing the production of proteins associated with proapoptosis and genes associated with tumor suppression.
Observation of the increased alternation of the mitochondrial membrane potential suggested that the extracts cause cancer cell death by both intrinsic and extrinsic apoptotic pathways.
The death of MCF-7-treated cells is also attributed to betanin/isobetanin induced autophagy.
Interestingly, the injection of betanin-enriched extract showed no obvious effect on normal cell lines.
Dr. Nowacki L, the lead scientist said, "the betanin/isobetanin mix as a therapeutic anticancer compound, alone or in combination with classical chemotherapeutic drugs, especially in functional p53 tumors".
In other words, betanin/isobetanin mix extracts processed anti-breast cancer cell proliferation by inducing cell death without affecting the integrity and viability of the normal breast cells.
In the analysis of the FDA-approved red food color E162, used in suppressing the development of multi-organ tumors in experimental animals, researchers compared the cytotoxic effect of the red beetroot extract with an anticancer drug, doxorubicin (Adriamycin) in the estrogen receptor-positive human breast cancer cells (MCF-7).
Beetroot extract exerted a significantly lower cancer cell inhibition compared to that doxorubicin.
The findings suggested that betanin, the major betacyanin constituent, may play an important role in the cytotoxicity exhibited by the red beetroot extract, according to the study.
Taken altogether, betanin used alone or combined with other phytochemicals may be considered supplements for the prevention and treatment of breast cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of betanin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Betanin-Enriched Red Beetroot (Beta vulgaris L.) Extract Induces Apoptosis and Autophagic Cell Death in MCF-7 Cells by Nowacki L1,2, Vigneron P2, Rotellini L2, Cazzola H1, Merlier F1, Prost E1, Ralanairina R3, Gadonna JP3, Rossi C1, Vayssade M2. (PubMed)
(2) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancercell lines by Kapadia GJ1, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
(3) Oral Contraceptives and Breast Cancer: A Review of the Epidemiological Evidence with an Emphasis on Younger Women by Kathleen E. Malone. (NCBI)
#Antioxidants #Isothiocyanates Kill Cancers in Vitros, According to Studies
By Kyle J. Norton
Dithiolthiones are phytochemicals in the class of Organosulfides, found abundantly in cruciferous vegetables, garden sorrel, horseradish, etc.
Cancer is a class of diseases in which a group of cells growing and multiplying in disordered and uncontrollable ways in our body, have become progressively worse and damage other healthy tissues, sometimes spreading to other organs in the body via lymph or blood and results may be in death.
In a case-control study conducted in urban Shanghai (from December 2006 to December 2008), ITC consumption from cruciferous vegetables showed a positive effect in reducing the risk of pancreatic cancer after adjusting for possible confounding factors such as age, sex, history of diabetes, and pancreatitis(1).
The study by Campus Morro do Cruzeiro suggested that the phytochemicals inhibited the cell viability of human cervical cancer cells, human pancreatic cancer cells, human hepatocellular carcinoma cells, and human ovarian cancer cells, and have anti-inflammatory properties in the treatment of human T-cell leukemia cells(3).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to 1000 free AND HEALTHY recipes and counting
http://kylejnorton.blogspot.ca/p/recipes.html
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
References
(1) [A case-control study on the association between urinary levels of isothiocyanates and the risk of pancreatic cancer].[Article in Chinese] by Wang J1, Han L, Zhang W, Wang J, Ni Q, Shen M, Gao Y2.(PubMed)
(2) Synthesis, antiproliferative and apoptosis-inducing activity of thiazolo[5,4-d]pyrimidines by Singh B1, Guru SK, Kour S, Jain SK, Sharma R, Sharma PR, Singh SK, Bhushan S, Bharate SB, Vishwakarma RA.(PubMed)
(3) The anti-oxidant properties of isothiocyanates: a review by de Figueiredo SM1, Filho SA, Nogueira-Machado JA, Caligiorne RB.(PubMed)
Dithiolthiones are phytochemicals in the class of Organosulfides, found abundantly in cruciferous vegetables, garden sorrel, horseradish, etc.
Cancer is a class of diseases in which a group of cells growing and multiplying in disordered and uncontrollable ways in our body, have become progressively worse and damage other healthy tissues, sometimes spreading to other organs in the body via lymph or blood and results may be in death.
In a case-control study conducted in urban Shanghai (from December 2006 to December 2008), ITC consumption from cruciferous vegetables showed a positive effect in reducing the risk of pancreatic cancer after adjusting for possible confounding factors such as age, sex, history of diabetes, and pancreatitis(1).
Thiazolo, the synthesis of a novel class of quinazoline, produced by the reaction of 4,6-dichloro-5-aminopyrimidine with isothiocyanates in the presence of 20 mol% KF/alumina, exhibited antiproliferative activity in the lung (NCI-H322 and A549), epidermal (A431) and glioblastoma (T98G), HL-60 cell lines at 20 μM. The effect of compound 4a on mitochondrial potential loss in HL-60 cells is probably through cleavage of PARP-1 and procaspase-3 inhibition(2).
The study by Campus Morro do Cruzeiro suggested that the phytochemicals inhibited the cell viability of human cervical cancer cells, human pancreatic cancer cells, human hepatocellular carcinoma cells, and human ovarian cancer cells, and have anti-inflammatory properties in the treatment of human T-cell leukemia cells(3).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to 1000 free AND HEALTHY recipes and counting
http://kylejnorton.blogspot.ca/p/recipes.html
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
References
(1) [A case-control study on the association between urinary levels of isothiocyanates and the risk of pancreatic cancer].[Article in Chinese] by Wang J1, Han L, Zhang W, Wang J, Ni Q, Shen M, Gao Y2.(PubMed)
(2) Synthesis, antiproliferative and apoptosis-inducing activity of thiazolo[5,4-d]pyrimidines by Singh B1, Guru SK, Kour S, Jain SK, Sharma R, Sharma PR, Singh SK, Bhushan S, Bharate SB, Vishwakarma RA.(PubMed)
(3) The anti-oxidant properties of isothiocyanates: a review by de Figueiredo SM1, Filho SA, Nogueira-Machado JA, Caligiorne RB.(PubMed)
#Herbal #CayennePepper in the Prevention and Treatment of Breast Cancer and Recurrent #BreastCancer, Researchers Say
By Kyle J. Norton
Scientists may have found a kitchen spice that processes the potential for reducing the risk and treatment of breast cancer, some studies suggested.
Breast cancer has emerged recently as the most common cancer that affects one in eight women during their lifetime in the US. The malignantly mammary cancer is characterized by the cell growth disorderly and uncontrollably first on the surface of the breast's inner linings either milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma).
However, there are rare cases that breast cancer starts in other areas of the breast.
In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S.
Breast cancer diagnosed at an early was found to have a 100% of the 5 years survival rate compared to stage II breast cancer at 93% and stage III breast cancer at 72%.
The exact causes of cell DNA in breast tissue alternation are unknown. However, scientists do know that certain risk factors such as aging, family history, smoking, and dense breast tissue are associated with an increased risk of breast cancer.
Genetic mutations inherited from parents such as BRCA1 and BRCA2, tumor protein 53 or P53, and Ataxia telangiectasia mutated (ATM) account for 5-10 percent of all breast cancer diagnosed every year.
However, inherited mutations that cause breast cancer are rare in the general population.
An unhealthy diet such as the Western diet with high in saturated and trans fat, red meat, and processed food and less in fruits and vegetables is also associated with an increased risk of breast cancer.
Dr. Stoll BA, in the assessment of the Western diet, early puberty, and breast cancer risk, explained,
"Both earlier menarche and adult tallness are markers of increased risk to breast cancer. Earlier menarche in the West is usually associated with earlier onset of hyperinsulinemia, and multiple case-control studies report that hyperinsulinemia too is a marker of increased breast cancer risk. Although the Western diet is linked both to earlier menarche and also to earlier hyperinsulinemia, the mechanism involved is not necessarily the same".
In lifestyle aspects, Dr.Harvie M, the lead author at the University Hospital of South Manchester NHS Foundation Trust, said, "Recent expert reports estimate that successful lifestyle changes could prevent 25% to 30% of cases of breast cancer".
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions.
Herbal medicine has been used in traditional medicine to increase metabolism, enhance the circulatory system and stomach and intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
In the study to reaffirm the effect of capsaicin as an anti-breast cancer agent, Dr. Dou D at the Wayne State University School of Medicine and Barbara Ann Karmanos Cancer Center, conducted an experiment to test whether capsaicin exhibits growth arrest and apoptosis in human breast cancer cell lines.
Although there are conflicting reports with regard to the value of hot peppers and their primary active component compound, capsaicin, as an anticancer agent, however, in vitro, breast cell growth inhibition and cell death induction were positively correlated with the capsaicin content of the peppers.
In other words, the effect of capsaicin on breast cancer proliferation and expansion is totally depending on the concentration which facilitates the production of antioxidants in the inhibition of free radical expression.
In MCF-7 cells, capsaicin was found to inhibit cancer cell growth and induces the cancer cells in a dose-dependent manner by reducing the levels of reactive oxygen species.
Further analysis also found that treatment of capsaicin also increased the apoptosis-inducing factor translocated into the cytosol and nucleus from the mitochondria and probably involved the pathways of caspase-independent that program breast cancer cell death
Dr. Constantinou C explained, " These pathways (pathways of caspase-independent programmed cell death (CI-PCD))are likely to be acting as 'death backup systems' that ensure effective removal of defective cells from the organism. Similar to classical apoptosis i.e. caspase-dependent programmed cell death (CD-PCD)".
Taken altogether, herbal Cayenne with high amounts of bioactive capsaicin may be considered a functional food for the prevention and treatment of breast cancer and the recurrence of breast cancer.
Women with a higher risk of breast cancer may want to add a small portion of chili pepper into their diet for preventive measures.
However, due to the limitation of the above studies, additional data collection large example size and multi-center studies performed with human consumption of the whole food or its bioactive compound emodin during the course of the disease will be necessary to complete the picture of herbal Cayenne, anti-breast cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Tumor cell growth inhibition is correlated with levels of capsaicin present in hot peppers by Dou D, Ahmad A, Yang H, Sarkar FH. (PubMed)
(2) Caspase-independent pathways of programmed cell death: the unraveling of new targets of cancer therapy? by Constantinou C1, Papas KA, Constantinou AI. (PubMed)
(3) Dietary and Lifestyle Risk Factors for Colorectal Cancer in Apparently Healthy Adults in Jordanian Hospitals by Omran S1, Barakat H2, Muliira JK3, McMillan S. (PubMed)
(4) Can diet and lifestyle prevent breast cancer: what is the evidence? by Harvie M1, Howell A1, Evans DG. (PubMed)
(5) Capsaicin-induced apoptosis in human breast cancer MCF-7 cells through the caspase-independent pathway by Chou CC, Wu YC, Wang YF, Chou MJ, Kuo SJ, Chen DR.(PubMed)
Scientists may have found a kitchen spice that processes the potential for reducing the risk and treatment of breast cancer, some studies suggested.
Breast cancer has emerged recently as the most common cancer that affects one in eight women during their lifetime in the US. The malignantly mammary cancer is characterized by the cell growth disorderly and uncontrollably first on the surface of the breast's inner linings either milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma).
However, there are rare cases that breast cancer starts in other areas of the breast.
In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S.
Breast cancer diagnosed at an early was found to have a 100% of the 5 years survival rate compared to stage II breast cancer at 93% and stage III breast cancer at 72%.
The exact causes of cell DNA in breast tissue alternation are unknown. However, scientists do know that certain risk factors such as aging, family history, smoking, and dense breast tissue are associated with an increased risk of breast cancer.
Genetic mutations inherited from parents such as BRCA1 and BRCA2, tumor protein 53 or P53, and Ataxia telangiectasia mutated (ATM) account for 5-10 percent of all breast cancer diagnosed every year.
However, inherited mutations that cause breast cancer are rare in the general population.
An unhealthy diet such as the Western diet with high in saturated and trans fat, red meat, and processed food and less in fruits and vegetables is also associated with an increased risk of breast cancer.
Dr. Stoll BA, in the assessment of the Western diet, early puberty, and breast cancer risk, explained,
"Both earlier menarche and adult tallness are markers of increased risk to breast cancer. Earlier menarche in the West is usually associated with earlier onset of hyperinsulinemia, and multiple case-control studies report that hyperinsulinemia too is a marker of increased breast cancer risk. Although the Western diet is linked both to earlier menarche and also to earlier hyperinsulinemia, the mechanism involved is not necessarily the same".
In lifestyle aspects, Dr.Harvie M, the lead author at the University Hospital of South Manchester NHS Foundation Trust, said, "Recent expert reports estimate that successful lifestyle changes could prevent 25% to 30% of cases of breast cancer".
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions.
Herbal medicine has been used in traditional medicine to increase metabolism, enhance the circulatory system and stomach and intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
In the study to reaffirm the effect of capsaicin as an anti-breast cancer agent, Dr. Dou D at the Wayne State University School of Medicine and Barbara Ann Karmanos Cancer Center, conducted an experiment to test whether capsaicin exhibits growth arrest and apoptosis in human breast cancer cell lines.
Although there are conflicting reports with regard to the value of hot peppers and their primary active component compound, capsaicin, as an anticancer agent, however, in vitro, breast cell growth inhibition and cell death induction were positively correlated with the capsaicin content of the peppers.
In other words, the effect of capsaicin on breast cancer proliferation and expansion is totally depending on the concentration which facilitates the production of antioxidants in the inhibition of free radical expression.
In MCF-7 cells, capsaicin was found to inhibit cancer cell growth and induces the cancer cells in a dose-dependent manner by reducing the levels of reactive oxygen species.
Further analysis also found that treatment of capsaicin also increased the apoptosis-inducing factor translocated into the cytosol and nucleus from the mitochondria and probably involved the pathways of caspase-independent that program breast cancer cell death
Dr. Constantinou C explained, " These pathways (pathways of caspase-independent programmed cell death (CI-PCD))are likely to be acting as 'death backup systems' that ensure effective removal of defective cells from the organism. Similar to classical apoptosis i.e. caspase-dependent programmed cell death (CD-PCD)".
Taken altogether, herbal Cayenne with high amounts of bioactive capsaicin may be considered a functional food for the prevention and treatment of breast cancer and the recurrence of breast cancer.
Women with a higher risk of breast cancer may want to add a small portion of chili pepper into their diet for preventive measures.
However, due to the limitation of the above studies, additional data collection large example size and multi-center studies performed with human consumption of the whole food or its bioactive compound emodin during the course of the disease will be necessary to complete the picture of herbal Cayenne, anti-breast cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Tumor cell growth inhibition is correlated with levels of capsaicin present in hot peppers by Dou D, Ahmad A, Yang H, Sarkar FH. (PubMed)
(2) Caspase-independent pathways of programmed cell death: the unraveling of new targets of cancer therapy? by Constantinou C1, Papas KA, Constantinou AI. (PubMed)
(3) Dietary and Lifestyle Risk Factors for Colorectal Cancer in Apparently Healthy Adults in Jordanian Hospitals by Omran S1, Barakat H2, Muliira JK3, McMillan S. (PubMed)
(4) Can diet and lifestyle prevent breast cancer: what is the evidence? by Harvie M1, Howell A1, Evans DG. (PubMed)
(5) Capsaicin-induced apoptosis in human breast cancer MCF-7 cells through the caspase-independent pathway by Chou CC, Wu YC, Wang YF, Chou MJ, Kuo SJ, Chen DR.(PubMed)
#Healthyfood #CelerySeed #Essentialoils, the Natural Repellent, According to Scientists
By Kyle J. Norton
Believe it or not, celery may be used as a repellent against insects.
A recent study suggested that celery in different varieties has exhibited significantly repellent effects on whiteflies, particularly Bemisia tabaci through their phytochemicals in the class of terpene, such as D-Limonene, β-myrcene, and (E)-β-ocimene.
Depending on the types of celery, some showed repellent effects relatively higher in volatilization quantities of β-myrcene than of D-limonene.
Celery is a species of Apium graveolens, belonging to the family Apiaceae, cultivated all around the globe as a vegetable. Celery can grow to 1/2 m tall with stalks (leaf on the top) arranged in a conical shape joined at a common base.
In the study of Aedes aegypti L., one of the primary disease vectors spreading various dreadful diseases, the essential oil extracted from the seeds of celery showed remarkably effective repellency of the oil leading to 100% protection till 165 min as compared to control, probably due to the presence of flavonoids, lactones, and terpenoids.
Dr. Kumar S, the lead researcher said, "Celery seed essential oil can be used as an efficient larvicide and repellent against Ae. Egypt" and ' The identification of the bioactive components, their mode of action, and studying effects on non-target organisms and the environment would help in devising mosquito-management strategies".
Furthermore, according to the Chiang Mai University, G10, celery (Apium graveolens)-based topical product exhibited not only similarity in appearance and physical properties, but also provided comparable repellency to that of the fresh preparation against a broad range of mosquito species belonging to various genera, including Aedes, Anopheles, Armigeres, Culex, and Mansonia, in comparison to the commercial (Insect Block 28) and standard (25% DEET) repellents.
In fact, because the G10 formula is a worthwhile product that expressed significantly promising results, including highly effective repellency with no potential skin irritation or other side effects, some researchers suggested that the product may be used as a potential natural alternative for personal protection against mosquitoes.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Repellent Effects of Different Celery Varieties in Bemisia tabaci (Hemiptera: Aleyrodidae) Biotype Q. by Tu H1,2, Qin Y2,(PubMed)
(2) Larvicidal, Repellent, and Irritant Potential of the Seed-Derived Essential oil of Apium graveolens Against Dengue Vector, Aedes aegypti L. (Diptera: Culicidae) by Kumar S1, Mishra M1, Wahab N1, Warikoo R1(PubMed)
(3) Field evaluation of G10, celery (Apium graveolens)-based topical repellent, against mosquitoes (Diptera: Culicidae) in Chiang Mai province, northern Thailand by Tuetun B1, Choochote W, Pongpaibul Y, Junkum A, Kanjanapothi D, Chaithong U, Jitpakdi A, Riyong D, Wannasan A, Pitasawat B.(PubMed)
(4) Celery-based topical repellents as a potential natural alternative for personal protection against mosquitoes by Tuetun B1, Choochote W, Pongpaibul Y, Junkum A, Kanjanapothi D, Chaithong U, Jitpakdi A, Riyong D, Pitasawat B.(PubMed)
Believe it or not, celery may be used as a repellent against insects.
A recent study suggested that celery in different varieties has exhibited significantly repellent effects on whiteflies, particularly Bemisia tabaci through their phytochemicals in the class of terpene, such as D-Limonene, β-myrcene, and (E)-β-ocimene.
Depending on the types of celery, some showed repellent effects relatively higher in volatilization quantities of β-myrcene than of D-limonene.
Celery is a species of Apium graveolens, belonging to the family Apiaceae, cultivated all around the globe as a vegetable. Celery can grow to 1/2 m tall with stalks (leaf on the top) arranged in a conical shape joined at a common base.
In the study of Aedes aegypti L., one of the primary disease vectors spreading various dreadful diseases, the essential oil extracted from the seeds of celery showed remarkably effective repellency of the oil leading to 100% protection till 165 min as compared to control, probably due to the presence of flavonoids, lactones, and terpenoids.
Dr. Kumar S, the lead researcher said, "Celery seed essential oil can be used as an efficient larvicide and repellent against Ae. Egypt" and ' The identification of the bioactive components, their mode of action, and studying effects on non-target organisms and the environment would help in devising mosquito-management strategies".
Furthermore, according to the Chiang Mai University, G10, celery (Apium graveolens)-based topical product exhibited not only similarity in appearance and physical properties, but also provided comparable repellency to that of the fresh preparation against a broad range of mosquito species belonging to various genera, including Aedes, Anopheles, Armigeres, Culex, and Mansonia, in comparison to the commercial (Insect Block 28) and standard (25% DEET) repellents.
In fact, because the G10 formula is a worthwhile product that expressed significantly promising results, including highly effective repellency with no potential skin irritation or other side effects, some researchers suggested that the product may be used as a potential natural alternative for personal protection against mosquitoes.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Sources
(1) Repellent Effects of Different Celery Varieties in Bemisia tabaci (Hemiptera: Aleyrodidae) Biotype Q. by Tu H1,2, Qin Y2,(PubMed)
(2) Larvicidal, Repellent, and Irritant Potential of the Seed-Derived Essential oil of Apium graveolens Against Dengue Vector, Aedes aegypti L. (Diptera: Culicidae) by Kumar S1, Mishra M1, Wahab N1, Warikoo R1(PubMed)
(3) Field evaluation of G10, celery (Apium graveolens)-based topical repellent, against mosquitoes (Diptera: Culicidae) in Chiang Mai province, northern Thailand by Tuetun B1, Choochote W, Pongpaibul Y, Junkum A, Kanjanapothi D, Chaithong U, Jitpakdi A, Riyong D, Wannasan A, Pitasawat B.(PubMed)
(4) Celery-based topical repellents as a potential natural alternative for personal protection against mosquitoes by Tuetun B1, Choochote W, Pongpaibul Y, Junkum A, Kanjanapothi D, Chaithong U, Jitpakdi A, Riyong D, Pitasawat B.(PubMed)
#Healthyfood #Fennel Inhibits the Risk of #IntestinalDysbiosis in Vivos, Scientists Show
By Kyle J. Norton
Fennel may have a potential and therapeutic effect in reduced risk, progression, and treatment of gastrointestinal dysbiosis, some scientists suggested.
Dysbiosis is the most common gastrointestinal tract disorder, caused by imbalanced microbiota in the gastrointestinal tract, particularly in the small intestines.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as a warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the investigation of the effect of some herbal essential oil in the risk of dysbiosis, researchers found that essential oil isolated from fennel exerts lesser inhibited function in a reduced concentration of the growth of potential pathogens in compared to the isolation of herbal Carum carvi, Lavandula angustifolia, Trachyspermum copticum, and Citrus aurantium var. Amara without inducing any adverse effects.
Further analysis also suggested that ingestion of fennel essential oil although decreases levels of bad micro bacteria concentration, they do not contribute to a substantial detrimental impact on beneficial members of the microflora.
The above differentiation was supported by the joint study conducted by the Scientific Board Member of Islamic Azad University, on 180 day-old broiler chicks to test the effect of the composition of Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fenne) on antimicrobial activity of gut microflora traits.
Application of the composition to samples chick randomly assigned to groups fed with control diet (without additives), a diet accompanied with 2 mentioned mixed powder plants (0.5% of the total diet), a diet with TF mixed powder plant, and diet with FV mixed powder plant, at the end of the experiment, demonstrated a significant improvement of balance of the gastrointestinal microflora, through an expression of increased average daily feed intake (ADFI), average daily gain (ADG).
Additionally, the efficacy of the composition also decreased the concentration of the number of G- bacteria (NGB), the number of Coli form bacteria compared to the sample taken before the experiment.
Indeed, the Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fennel) treated group displayed an enormous anti-antimicrobial activity of the gut, compared to the control group.
In tested porcine gut, anethole, the bioactive compound found in essential oil isolated from fennel displayed a substantial antimicrobial activity against commensal and pathogenic bacteria, through inhibited the chloride secretion with function in major determinant of mucosal hydration throughout the gastrointestinal tract, induced by 5-HT metabolic signaling of gut microbes and theophylline adverse effect in the induction of gut disorder.
At a dose of 0.5 mmol/L, anethole exerted a protective effect against micro imbalance in initiated gastrointestinal disorder by inhibition of excessive chloride secretion.
Taken together, the information finding suggested that fennel and its bioactive compound anethole may be considered as a functional herb for reduced risk, and progression and combined with standard medicine for the treatment of intestinal dysbiosis, without inducing intolerant side effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study by Hawrelak JA1, Cattley T, Myers SP. (PubMed)
(2) Effects of fenugreek and fennel seeds on growth performance and reducing the population of gut microflora in broiler chicks [2010] by Kalantar, M.,Dakhili, M.,(PubMed)
(3) EFFECT OF THE ESSENTIAL OILS THYMOL, E-ANETHOLE AND ECINNAMALDEHYDE ON ACTIVE NUTRIENT ABSORPTION AND STIMULATED CHLORIDE SECRETION IN THE ISOLATED PIG GUT, Chapter 5 by JORIS MICHIELS
Fennel may have a potential and therapeutic effect in reduced risk, progression, and treatment of gastrointestinal dysbiosis, some scientists suggested.
Dysbiosis is the most common gastrointestinal tract disorder, caused by imbalanced microbiota in the gastrointestinal tract, particularly in the small intestines.
Fennel (Foeniculum vulgare) is a plant species of the genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as a warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
In the investigation of the effect of some herbal essential oil in the risk of dysbiosis, researchers found that essential oil isolated from fennel exerts lesser inhibited function in a reduced concentration of the growth of potential pathogens in compared to the isolation of herbal Carum carvi, Lavandula angustifolia, Trachyspermum copticum, and Citrus aurantium var. Amara without inducing any adverse effects.
Further analysis also suggested that ingestion of fennel essential oil although decreases levels of bad micro bacteria concentration, they do not contribute to a substantial detrimental impact on beneficial members of the microflora.
The above differentiation was supported by the joint study conducted by the Scientific Board Member of Islamic Azad University, on 180 day-old broiler chicks to test the effect of the composition of Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fenne) on antimicrobial activity of gut microflora traits.
Application of the composition to samples chick randomly assigned to groups fed with control diet (without additives), a diet accompanied with 2 mentioned mixed powder plants (0.5% of the total diet), a diet with TF mixed powder plant, and diet with FV mixed powder plant, at the end of the experiment, demonstrated a significant improvement of balance of the gastrointestinal microflora, through an expression of increased average daily feed intake (ADFI), average daily gain (ADG).
Additionally, the efficacy of the composition also decreased the concentration of the number of G- bacteria (NGB), the number of Coli form bacteria compared to the sample taken before the experiment.
Indeed, the Trigonella foenum-graecum (Fenugreek) and Foeniculum vulgare (Fennel) treated group displayed an enormous anti-antimicrobial activity of the gut, compared to the control group.
In tested porcine gut, anethole, the bioactive compound found in essential oil isolated from fennel displayed a substantial antimicrobial activity against commensal and pathogenic bacteria, through inhibited the chloride secretion with function in major determinant of mucosal hydration throughout the gastrointestinal tract, induced by 5-HT metabolic signaling of gut microbes and theophylline adverse effect in the induction of gut disorder.
At a dose of 0.5 mmol/L, anethole exerted a protective effect against micro imbalance in initiated gastrointestinal disorder by inhibition of excessive chloride secretion.
Taken together, the information finding suggested that fennel and its bioactive compound anethole may be considered as a functional herb for reduced risk, and progression and combined with standard medicine for the treatment of intestinal dysbiosis, without inducing intolerant side effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.
Sources
(1) Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study by Hawrelak JA1, Cattley T, Myers SP. (PubMed)
(2) Effects of fenugreek and fennel seeds on growth performance and reducing the population of gut microflora in broiler chicks [2010] by Kalantar, M.,Dakhili, M.,(PubMed)
(3) EFFECT OF THE ESSENTIAL OILS THYMOL, E-ANETHOLE AND ECINNAMALDEHYDE ON ACTIVE NUTRIENT ABSORPTION AND STIMULATED CHLORIDE SECRETION IN THE ISOLATED PIG GUT, Chapter 5 by JORIS MICHIELS
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