By Kyle J. Norton
Cancer is a class of diseases caused by irregular cell growth due to the alternation of the DNA.
After penetrating into deeper layer tissues of a specific organ, the proliferative tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.
The most advanced stage of cancer may result in the death of the patient.
The ovaries are an -shaped ovum-producing reproductive organ in part of a woman's reproductive system connected to the fallopian tubes and attached to the outer layer of the uterus via the ovarian ligament. Usually, the left and right ovaries take a turn to release an egg every month.
Ovarian cancer is a condition of abnormal cell growth of ovarian cells that start in the cells on the surface of the inner lining tissue of the ovary and have become cancerous. Ovarian cancer is one of the most common cancers in the US, according to the statistics adapted from the American Cancer Society's publication,.
Cancer Facts & Figures 2010, an estimated 21,880 women in the United States will be diagnosed with ovarian cancer and 13,850 deaths.
The exact causes of ovarian cancer are unknown. However, the most common prevalent factors associated with increased risk of ovarian cancer are
*Age
The risk of ovarian cancer increases for women between 50 to 70 years of age.
* Genetic preposition
Women who carry certain mutation genes such as BRCA1 and BRCA2 account for 5%–13% of ovarian cancers.
* Family history
The risk of the disease increases if one of your direct member's family has a history of cancer.
* Never pregnant
Researchers found that the risk of ovarian cancer is lower with the number of pregnancies.
* Race
White women are associated with a higher risk than other races.
* Hormone therapy
Risk of ovarian cancer increase with the use of hormone replacement therapy in postmenopausal women.
* Chemical exposures
Certain chemicals such as asbestos also increase the risk of ovarian cancer.
* High-fat dietary
Researchers found that women who diet high in saturated fat and trans fat are at higher risk.
* Fertility medication
Drugs used to enhance fertility such as Clomiphene citrate may increase the risk of ovarian cancer.
* Milk
According to the BBC, researchers found that women who drank two or more glasses a day were at double the risk of those who did not consume it at all, or only in small amounts.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation to garlic. It is often called the "king of vegetables" because of its pungent taste and found in many recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.
In finding a potential compound for the treatment of lung cancer, researchers examined the effects of onionin A (ONA) derived from the onion in the inhibition of tumor-associated macrophages (TAMs) in the M2 phenotype.
According to the tested analysis.* Onionin A (ONA )inhibits ovarian cancer cell proliferation induced by co-culture with human macrophages.
* Onionin A directly suppressed lung cancer cell proliferation.
* Onionin A enhanced the effects of anti-cancer drugs was also observed.
* In ovarian cancer cells. signal transducer and activator of transcription 3 (STAT3) involved in cell proliferation and chemo-resistance were significantly suppressed by ONA.
* Additionally, ONA inhibited cancer progression and prolonged the survival time in a murine ovarian cancer model under single and combined with chemo drug treatment conditions.
Based on the finding, researchers said, "ONA is considered useful for the additional treatment of patients with lung cancer owing to its suppression of the pro-tumor activation of tumor-associated macrophages (TAMs) and direct cytotoxicity against cancer cells".
Taken altogether, onion processed with a higher amount of onionin A (ONA) may be considered a remedy for the prevention and treatment of ovarian cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages by Tsuboki J1,2, Fujiwara Y1, Horlad H1, Shiraishi D1, Nohara T3, Tayama S2, Motohara T2, Saito Y1, Ikeda T3, Takaishi K2, Tashiro H4, Yonemoto Y5, Katabuchi H2, Takeya M1, Komohara Y. (PubMed)
(2) Lung Cancer by Kyle J. Norton
Saturday, 13 May 2023
#Herbal #Chamomile Protects the Liver Against the Onset of Liver Diseases, Researchers Show
By Kyle J. Norton
Chamomile is also known as camomile, the common name of many species of daisy-like plants in the family Asteraceae. The herb has been used in traditional medicine as an antispasmodic and anti-inflammatory constituent to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
Chamomilla Recutita flavonoids (chamiloflan) showed to exhibit antioxidant and anti-inflammatory effects through the induced decrease of ceramide levels in the liver of old rats, according to the Kharkov Karazin National University(1).
Chamomile is also known as camomile, the common name of many species of daisy-like plants in the family Asteraceae. The herb has been used in traditional medicine as an antispasmodic and anti-inflammatory constituent to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
Chamomilla Recutita flavonoids (chamiloflan) showed to exhibit antioxidant and anti-inflammatory effects through the induced decrease of ceramide levels in the liver of old rats, according to the Kharkov Karazin National University(1).
Flavonoids of German chamomile also exhibited the hepatoprotective effect, through affect sphingolipid metabolism and reducing the elevated ceramide level in the aged liver by normalized activities of key enzymes of sphingolipid turnover (neutral SMase and ceramidase) and ceramide contents in the damaged liver and liver cells, and stabilized the hepatocyte membranes. (2)
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to 1000 free AND HEALTHY recipes and counting
http://kylejnorton.blogspot.ca/p/recipes.html
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
References
(a) Guaianolides and volatile compounds in chamomile tea by Tschiggerl C1, Bucar F.(PubMed)
(b) Quantitative determination of phenolic compounds by UHPLC-UV-MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads by Avula B1, Wang YH, Wang M, Avonto C, Zhao J, Smillie TJ, Rua D, Khan IA.(PubMed)
(1a) Anxiety disorder(Canadian mental health association)
References
(1) Effects of Chamomilla recutita flavonoids on age-related liver sphingolipid turnover in rats.
Babenko NA1, Shakhova EG.(PubMed)
(2) Effects of flavonoids on sphingolipid turnover in the toxin-damaged liver and liver cells by Babenko NA1, Shakhova EG.(PubMed)
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to 1000 free AND HEALTHY recipes and counting
http://kylejnorton.blogspot.ca/p/recipes.html
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
References
(a) Guaianolides and volatile compounds in chamomile tea by Tschiggerl C1, Bucar F.(PubMed)
(b) Quantitative determination of phenolic compounds by UHPLC-UV-MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads by Avula B1, Wang YH, Wang M, Avonto C, Zhao J, Smillie TJ, Rua D, Khan IA.(PubMed)
(1a) Anxiety disorder(Canadian mental health association)
References
(1) Effects of Chamomilla recutita flavonoids on age-related liver sphingolipid turnover in rats.
Babenko NA1, Shakhova EG.(PubMed)
(2) Effects of flavonoids on sphingolipid turnover in the toxin-damaged liver and liver cells by Babenko NA1, Shakhova EG.(PubMed)
Artichoke, The Herb that Regulates Insulin Response, According to Studies
By Kyle J. Norton
Insulin response is a process of your body that reacts to the dietary intake.
Insulin produced by the pancreas is a hormone that binds the insulin receptors in the promotion of cells of the intestines to convert glucose to energy for the body's needs.
Acute insulin response was used as the predictor of type 2 diabetes by diagnosing both regular fasting and 2-h plasma glucose concentrations.
Compared to a healthy individual with normal insulin response, most patients with prediabetes and diabetes have elevated fasting and 2 hours of plasma glucose concentration.
There are many risk factors associated with the abnormal insulinemic response. However, some researchers suggested that the gradual dying of the beta cells of the pancreas and insulin receptor sites clogging up by cholesterol are 2 of the major causes that affect insulin expression.
Some researchers suggested that abnormal insulin response may be correlated to the widespread obesity that leads to insulin resistance in the Western world.
Dr. Olga T. Hardy, in the evaluation of the causes of insulin resistance underlying obesity, wrote,
"The association between obesity and insulin resistance is an area of much interest and enormous public health impact".
And, "Visceral adiposity is correlated with the accumulation of excess lipid in the liver and results in cell-autonomous impairment in insulin signaling. Visceral adipose tissue is also prone to inflammation and inflammatory cytokine production, which also contribute to impairment in insulin signaling".
The results strongly suggested if you are obese, your risk of insulin resistance increased substantially compared to overweight or healthy-weight individuals.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas, bloating, etc.
Researchers on finding a potential natural ingredient for the modulation of insulinemic response, researchers investigate the impact of the supplementation of a pre-biotic compound [Jerusalem artichoke meal (JAM)] on the glycaemic and insulinemic response in healthy, non-obese warm-blooded horses.
The study included 6 adult mares fed with crushed oat grains (1 g starch/kg bwt per day) and meadow hay (2 kg/100 kg bwt per day) together with either 0.15 g fructooligosaccharides and inulin (FOS+INU)/kg bwt per day via commercial JAM or maize cob meal without grains as control (CON) in 2 × 3-week periods according to a crossover design.
According to the sample collected at the postprandial (PP) time points (-60, 0, 30, 60, 90, 120, 180, 240, and 300 min), and the plasma glucose and serum insulin levels, JAM vs. CON did not change the PP peak of glucose or insulin (glucose: 6.3 ± 0.40 vs. 7.0 ± 0.87 mmol/l.
However, following JAM feeding, glucose and insulin levels declined more rapidly until 240 min PP compared to animals fed with CON.
The finding suggested that JAM exerted a significant effect on postprandial (PP) glucose and insulin levels on and after the time points of 240 min.
Furthermore, in order to reveal more information about JA insulinemic response, researchers compared the Jerusalem artichoke (Helianthus tuberosus Linne, HTL) and chungkookjang (CKJ; fermented soybeans) in energy and glucose metabolism.
The study included rats divided into partially pancreatectomized (Px) diabetic rats and sham-operated non-diabetic control rats and all fed high-fat diets. Additionally, diabetic rats were subdivided into an untreated diabetic control group and those fed with 5% HTL, 5% CKJ, or 5% HTL+5% CKJ for 8 weeks. HTL+CKJ treatment reduced visceral fat without modulating energy intake compared to diabetic control.
According to the hyperinsulinemic-euglycemic assay, rats treated with HTL, HTL+CKJ showed an improvement in glucose tolerance, compared to the diabetic normal-control group.
CKJ and CKJ+HTL but not HTL, injection groups increased first and second-phase insulin secretion compared to diabetic control.
Moreover, the glucose infusion rates (mg/kg bw/min) and hepatic insulin sensitivity were increased and CKJ+HTL (13.5), but not HTL (9.4) or CKJ (9.5) alone, and HTL and CKJ+ HTL decreased hepatic glucose compared to diabetic control.
Dr. Yang HJ, the lead scientist wrote in the final report, "HTL and CKJ enhanced glucose tolerance in different manners, and exhibited partially additive and complementary effects by reversing insulin resistance and enhancing β-cell function in diabetic rats".
Taken altogether, artichoke used alone or combined with another herbal remedy may be considered functional food for the enhancement of insulinemic response against the onset of diabetes, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Glycaemic and insulinemic responses of adult healthy warm-blooded mares following feeding with Jerusalem artichoke meal by Glatter M1, Bochnia M1, Goetz F1, Gottschalk J2, Koeller G3, Mielenz N4, Hillegeist D5, Greef JM5, Einspanier A2, Zeyner A. (PubMed)
(2) Jerusalem artichoke and chungkookjang additively improve insulin secretion and sensitivity in diabetic rats by Yang HJ1, Kwon DY, Kim MJ, Kang S, Kim DS, Park S. (PubMed)
(3) What causes the insulin resistance underlying obesity? by Olga T. Hardy, Michael P. Czech, and Silvia Corvera. (PMC)
Insulin response is a process of your body that reacts to the dietary intake.
Insulin produced by the pancreas is a hormone that binds the insulin receptors in the promotion of cells of the intestines to convert glucose to energy for the body's needs.
Acute insulin response was used as the predictor of type 2 diabetes by diagnosing both regular fasting and 2-h plasma glucose concentrations.
Compared to a healthy individual with normal insulin response, most patients with prediabetes and diabetes have elevated fasting and 2 hours of plasma glucose concentration.
There are many risk factors associated with the abnormal insulinemic response. However, some researchers suggested that the gradual dying of the beta cells of the pancreas and insulin receptor sites clogging up by cholesterol are 2 of the major causes that affect insulin expression.
Some researchers suggested that abnormal insulin response may be correlated to the widespread obesity that leads to insulin resistance in the Western world.
Dr. Olga T. Hardy, in the evaluation of the causes of insulin resistance underlying obesity, wrote,
"The association between obesity and insulin resistance is an area of much interest and enormous public health impact".
And, "Visceral adiposity is correlated with the accumulation of excess lipid in the liver and results in cell-autonomous impairment in insulin signaling. Visceral adipose tissue is also prone to inflammation and inflammatory cytokine production, which also contribute to impairment in insulin signaling".
The results strongly suggested if you are obese, your risk of insulin resistance increased substantially compared to overweight or healthy-weight individuals.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas, bloating, etc.
Researchers on finding a potential natural ingredient for the modulation of insulinemic response, researchers investigate the impact of the supplementation of a pre-biotic compound [Jerusalem artichoke meal (JAM)] on the glycaemic and insulinemic response in healthy, non-obese warm-blooded horses.
The study included 6 adult mares fed with crushed oat grains (1 g starch/kg bwt per day) and meadow hay (2 kg/100 kg bwt per day) together with either 0.15 g fructooligosaccharides and inulin (FOS+INU)/kg bwt per day via commercial JAM or maize cob meal without grains as control (CON) in 2 × 3-week periods according to a crossover design.
According to the sample collected at the postprandial (PP) time points (-60, 0, 30, 60, 90, 120, 180, 240, and 300 min), and the plasma glucose and serum insulin levels, JAM vs. CON did not change the PP peak of glucose or insulin (glucose: 6.3 ± 0.40 vs. 7.0 ± 0.87 mmol/l.
However, following JAM feeding, glucose and insulin levels declined more rapidly until 240 min PP compared to animals fed with CON.
The finding suggested that JAM exerted a significant effect on postprandial (PP) glucose and insulin levels on and after the time points of 240 min.
Furthermore, in order to reveal more information about JA insulinemic response, researchers compared the Jerusalem artichoke (Helianthus tuberosus Linne, HTL) and chungkookjang (CKJ; fermented soybeans) in energy and glucose metabolism.
The study included rats divided into partially pancreatectomized (Px) diabetic rats and sham-operated non-diabetic control rats and all fed high-fat diets. Additionally, diabetic rats were subdivided into an untreated diabetic control group and those fed with 5% HTL, 5% CKJ, or 5% HTL+5% CKJ for 8 weeks. HTL+CKJ treatment reduced visceral fat without modulating energy intake compared to diabetic control.
According to the hyperinsulinemic-euglycemic assay, rats treated with HTL, HTL+CKJ showed an improvement in glucose tolerance, compared to the diabetic normal-control group.
CKJ and CKJ+HTL but not HTL, injection groups increased first and second-phase insulin secretion compared to diabetic control.
Moreover, the glucose infusion rates (mg/kg bw/min) and hepatic insulin sensitivity were increased and CKJ+HTL (13.5), but not HTL (9.4) or CKJ (9.5) alone, and HTL and CKJ+ HTL decreased hepatic glucose compared to diabetic control.
Dr. Yang HJ, the lead scientist wrote in the final report, "HTL and CKJ enhanced glucose tolerance in different manners, and exhibited partially additive and complementary effects by reversing insulin resistance and enhancing β-cell function in diabetic rats".
Taken altogether, artichoke used alone or combined with another herbal remedy may be considered functional food for the enhancement of insulinemic response against the onset of diabetes, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been referenced in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Glycaemic and insulinemic responses of adult healthy warm-blooded mares following feeding with Jerusalem artichoke meal by Glatter M1, Bochnia M1, Goetz F1, Gottschalk J2, Koeller G3, Mielenz N4, Hillegeist D5, Greef JM5, Einspanier A2, Zeyner A. (PubMed)
(2) Jerusalem artichoke and chungkookjang additively improve insulin secretion and sensitivity in diabetic rats by Yang HJ1, Kwon DY, Kim MJ, Kang S, Kim DS, Park S. (PubMed)
(3) What causes the insulin resistance underlying obesity? by Olga T. Hardy, Michael P. Czech, and Silvia Corvera. (PMC)
#Herbal #Ashwagandha In Reducing the Risk of #ColorectalCancer, Researchers Find
By Kyle J. Norton
The bowel is divided into the small bowel (or small intestine) and the large bowel (or colon and rectum). The large intestine formed a part of the bowel in the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Colorectal cancer is a chronic disease associated with a malignant tumor in the colon or rectum that begins in the cell on the surface of the inner lining of the colon or rectum before proliferating into deeper tissues to form a tumor due to the alternation of cell DNA.
Most cases of colorectal cancer are diagnosed in developed countries, including the U.S. and Canada.
The disease also is relatively very common and slowly growing and progressing with cancer with a tendency that is easy to predict.
According to the statistics provided by the American Cancer Society in 2019, approximately
101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
Furthermore, the overall, lifetime risk colorectal cancer of developing is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Due to the slow growth in nature, most people with colorectal cancer do not experience any symptoms until the advanced stage.
The most common symptoms of colorectal cancer at the late stage can induce symptoms of change of bowel movement, bloody stool, and persistent abdominal discomforts, such as cramps, gas, or pain, accompanied by unintended weight loss, fatigue, and loss of appetite,
If you experience some of the above symptoms, please contact your doctor to rule out the possibility of colorectal cancer.
At this advanced stage, colorectal cancer cells can also travel a distance away to infect other healthy tissue and organs, leading to a second metastasis.
Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent ingredient for the treatment of colorectal cancer, scientists investigated the effects of Withaferin A (WA), an active steroidal lactone derived from the herbal plant Withania somnifera (Ashwagandha), on reactive oxygen species (ROS) induced colorectal cancer model.
According to the tested differentiation, withaferin A showed significant activity in inducing apoptosis and cell cycle arrest in human colon cancer cells.
ROS accumulation that causes mitochondrial dysfunction associated with a cellular network of organelles involved in cancer cell progression was also eradicated by the injection of withaferin A.
In other words, withaferin A-induced ROS-mediated cell cycle arrest and the expression of apoptotic proteins by promoting colorectal cancer cell death resulting in decreased mitochondrial membrane potential accompanying mitochondrial dysfunction.
On HCT-116 and RKO cells, WA exhibited cytotoxicity in a dose-dependent manner.
Based on the findings, researchers said, " these results strongly indicated that WA directly inhibits cell growth and induces apoptosis in CRC cells through ROS-mediated mitochondrial dysfunction and c-Jun N-terminal kinases (JNKs) induced apoptosis)".
Taken altogether, Ashwagandha processed abundantly bioactive compound withaferin A may be considered a functional herb for the prevention and treatment of colorectal cancer, pending to larger sample and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells by Xia S1, Miao Y2, Liu S. (PubMed)
(2) Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity by Choi BY1, Kim BW. (PubMed)
The bowel is divided into the small bowel (or small intestine) and the large bowel (or colon and rectum). The large intestine formed a part of the bowel in the digestive system is involved in the absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Colorectal cancer is a chronic disease associated with a malignant tumor in the colon or rectum that begins in the cell on the surface of the inner lining of the colon or rectum before proliferating into deeper tissues to form a tumor due to the alternation of cell DNA.
Most cases of colorectal cancer are diagnosed in developed countries, including the U.S. and Canada.
The disease also is relatively very common and slowly growing and progressing with cancer with a tendency that is easy to predict.
According to the statistics provided by the American Cancer Society in 2019, approximately
101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
Furthermore, the overall, lifetime risk colorectal cancer of developing is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Due to the slow growth in nature, most people with colorectal cancer do not experience any symptoms until the advanced stage.
The most common symptoms of colorectal cancer at the late stage can induce symptoms of change of bowel movement, bloody stool, and persistent abdominal discomforts, such as cramps, gas, or pain, accompanied by unintended weight loss, fatigue, and loss of appetite,
If you experience some of the above symptoms, please contact your doctor to rule out the possibility of colorectal cancer.
At this advanced stage, colorectal cancer cells can also travel a distance away to infect other healthy tissue and organs, leading to a second metastasis.
Ashwagandha also known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered Indian ginseng and used in Ayurvedic medicine for over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered an anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent ingredient for the treatment of colorectal cancer, scientists investigated the effects of Withaferin A (WA), an active steroidal lactone derived from the herbal plant Withania somnifera (Ashwagandha), on reactive oxygen species (ROS) induced colorectal cancer model.
According to the tested differentiation, withaferin A showed significant activity in inducing apoptosis and cell cycle arrest in human colon cancer cells.
ROS accumulation that causes mitochondrial dysfunction associated with a cellular network of organelles involved in cancer cell progression was also eradicated by the injection of withaferin A.
In other words, withaferin A-induced ROS-mediated cell cycle arrest and the expression of apoptotic proteins by promoting colorectal cancer cell death resulting in decreased mitochondrial membrane potential accompanying mitochondrial dysfunction.
On HCT-116 and RKO cells, WA exhibited cytotoxicity in a dose-dependent manner.
Based on the findings, researchers said, " these results strongly indicated that WA directly inhibits cell growth and induces apoptosis in CRC cells through ROS-mediated mitochondrial dysfunction and c-Jun N-terminal kinases (JNKs) induced apoptosis)".
Taken altogether, Ashwagandha processed abundantly bioactive compound withaferin A may be considered a functional herb for the prevention and treatment of colorectal cancer, pending to larger sample and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells by Xia S1, Miao Y2, Liu S. (PubMed)
(2) Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity by Choi BY1, Kim BW. (PubMed)
Friday, 12 May 2023
#Herbal #Gingers Process Antibiotics Properties, Researchers Find
By Kyle J. Norton
Ginger may be considered a natural antibiotics alternative for the treatment of Candida albicans overgrowth without inducing any side effects, some scientists suggested.
Candida albicans is an opportunistic pathogenic yeast formed part of the commensal gastrointestinal mycobiota.
Candida albicans overgrowth is the most prevalent cause of fungal infections in humans.
Epidemiological studies strongly suggested that long-term users of antibiotics that cause an imbalance of the gut microbiome, weakened immune system, unhealthy diet, and women who are pregnant and hormone imbalance of hormone near menstruation are susceptible to the onset of the condition.
If you experience symptoms of oral thrush, recurring genital or urinary tract infections, persistent digestive issues, or joint pain. particularly, in the skin and nail fungal infections, you may have a yeast infection.
Please check with your doctor to rule out the Candida albicans overgrowth possibility.
Dr. Carol A. Kumamoto in the research team of infectious diseases in the study "Inflammation and gastrointestinal Candida colonization" suggested that Candida albicans overgrowth can be caused by other medical conditions, associated with a digestive disorder.
In the study, the doctor wrote, "Recent studies, however, show that high-level Candida colonization is associated with several diseases of the gastrointestinal tract. Further, results from animal models argue that Candida colonization delays the healing of inflammatory lesions and that inflammation promotes colonization".
And, "Both inflammatory bowel disease and gastrointestinal Candida colonization are associated with elevated levels of the pro-inflammatory cytokine IL-17. Therefore, effects on IL-17 levels may underlie the ability of Candida colonization to enhance inflammation".
These results strongly suggested inflammation flames the overgrowth of Candida colonization in return, the overgrowth of Candida albicans induces persistently low-grade inflammation.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find the natural ingredient or whole food for the replacement of conventional antibiotics without inducing any effects, researchers at the Teikyo University Institute of Medical Mycology investigated the effect of ginger against infection caused by Candida albicans.
4 preparations of the essential oils of young and mature rhizomes, air-dried and steamed rhizomes, and seed rhizomes of Zingiber officinale Roscoe (ginger) were compared in the study.
* All ginger essential oils processed a significant anti-Candida albicans activity.
* Essential oil from the seed and air-dried rhizomes, exerted the highest effect compared to other preparations.
* The seed and air-dried rhizomes essential oils also had a potent inhibitory activity compared to ginger oleoresins obtained by ethanol and hypercritical carbon dioxide extraction and essential oils of 5 other plants in the family Zingiberaceae.
According to the chemical constituents assay, [6]-shogaol was most active against filament formation and growth of C. Albicans, followed by citral and [6]-gingerol.
Furthermore, ginger oleoresin, especially that obtained by ethanol extraction, with a high [6]-gingerol content exhibited potent anti-growth of C. Albicans compared to essential oils of ginger and other Zingiberaceae plants.
Moreover, in a vitro joint study by the Institute of Science and Technology, researchers launched an investigation to evaluate the antimicrobial activity of 2% chlorhexidine gel (CHX) isolated from ginger as an auxiliary chemical substance and intracanal medications on Candida albicans.
The study included 48 single-rooted human teeth randomly divided into four groups (n = 12), according to intracanal medications used: (1) Calcium hydroxide + a pyrogenic saline solution (Ca(OH)2 + SS), (2) 20% ginger glycolic extract (GEN), (3) calcium hydroxide + 20% ginger glycolic extract (Ca(OH)2 + GEN), (4) a pyrogenic SS (control).
At the end of the experiment, researchers found that
* CHX was effective in the complete elimination of E. coli and C. albicans.
* ChX also significantly reduced and then completely eliminated E. faecalis after intracanal medication.
* All other applications also revealed a reduction of endotoxins, the outer membrane of the cell wall of Gram-negative bacteria.
In the final report, the research team concluded, "CHX and intracanal medication used were able to eliminate the microorganisms from the root canal; the endotoxins were reduced, yet not completely eliminated".
These results strongly suggested that ginger bioactive compound processes a significant antibacterial activity, particularly in those of C. albicans.
Taken together, there is no doubt that ginger may be considered a functional food for the prevention and combined with primary medicine for the treatment of yeast infection with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-Candida and radical scavenging activities of essential oils and oleoresins of Zingiber officinale Roscoe and essential oils of other plants belonging to the family Zingiberaceae by Takahashi M1, Inouye S, Abe S.(PubMed)
(2) Action of Chlorhexidine, Zingiber officinale, and Calcium Hydroxide on Candidaalbicans, Enterococcus faecalis, Escherichia coli, and Endotoxin in the Root Canals by Valera MC1, Oliveira SA2, Maekawa LE2, Cardoso FG3, Chung A2, Silva SF2, Carvalho CA2. (PubMed)
(3) Inflammation and gastrointestinal Candida colonization by Carol A. Kumamoto. (PMC)
Ginger may be considered a natural antibiotics alternative for the treatment of Candida albicans overgrowth without inducing any side effects, some scientists suggested.
Candida albicans is an opportunistic pathogenic yeast formed part of the commensal gastrointestinal mycobiota.
Candida albicans overgrowth is the most prevalent cause of fungal infections in humans.
Epidemiological studies strongly suggested that long-term users of antibiotics that cause an imbalance of the gut microbiome, weakened immune system, unhealthy diet, and women who are pregnant and hormone imbalance of hormone near menstruation are susceptible to the onset of the condition.
If you experience symptoms of oral thrush, recurring genital or urinary tract infections, persistent digestive issues, or joint pain. particularly, in the skin and nail fungal infections, you may have a yeast infection.
Please check with your doctor to rule out the Candida albicans overgrowth possibility.
Dr. Carol A. Kumamoto in the research team of infectious diseases in the study "Inflammation and gastrointestinal Candida colonization" suggested that Candida albicans overgrowth can be caused by other medical conditions, associated with a digestive disorder.
In the study, the doctor wrote, "Recent studies, however, show that high-level Candida colonization is associated with several diseases of the gastrointestinal tract. Further, results from animal models argue that Candida colonization delays the healing of inflammatory lesions and that inflammation promotes colonization".
And, "Both inflammatory bowel disease and gastrointestinal Candida colonization are associated with elevated levels of the pro-inflammatory cytokine IL-17. Therefore, effects on IL-17 levels may underlie the ability of Candida colonization to enhance inflammation".
These results strongly suggested inflammation flames the overgrowth of Candida colonization in return, the overgrowth of Candida albicans induces persistently low-grade inflammation.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find the natural ingredient or whole food for the replacement of conventional antibiotics without inducing any effects, researchers at the Teikyo University Institute of Medical Mycology investigated the effect of ginger against infection caused by Candida albicans.
4 preparations of the essential oils of young and mature rhizomes, air-dried and steamed rhizomes, and seed rhizomes of Zingiber officinale Roscoe (ginger) were compared in the study.
* All ginger essential oils processed a significant anti-Candida albicans activity.
* Essential oil from the seed and air-dried rhizomes, exerted the highest effect compared to other preparations.
* The seed and air-dried rhizomes essential oils also had a potent inhibitory activity compared to ginger oleoresins obtained by ethanol and hypercritical carbon dioxide extraction and essential oils of 5 other plants in the family Zingiberaceae.
According to the chemical constituents assay, [6]-shogaol was most active against filament formation and growth of C. Albicans, followed by citral and [6]-gingerol.
Furthermore, ginger oleoresin, especially that obtained by ethanol extraction, with a high [6]-gingerol content exhibited potent anti-growth of C. Albicans compared to essential oils of ginger and other Zingiberaceae plants.
Moreover, in a vitro joint study by the Institute of Science and Technology, researchers launched an investigation to evaluate the antimicrobial activity of 2% chlorhexidine gel (CHX) isolated from ginger as an auxiliary chemical substance and intracanal medications on Candida albicans.
The study included 48 single-rooted human teeth randomly divided into four groups (n = 12), according to intracanal medications used: (1) Calcium hydroxide + a pyrogenic saline solution (Ca(OH)2 + SS), (2) 20% ginger glycolic extract (GEN), (3) calcium hydroxide + 20% ginger glycolic extract (Ca(OH)2 + GEN), (4) a pyrogenic SS (control).
At the end of the experiment, researchers found that
* CHX was effective in the complete elimination of E. coli and C. albicans.
* ChX also significantly reduced and then completely eliminated E. faecalis after intracanal medication.
* All other applications also revealed a reduction of endotoxins, the outer membrane of the cell wall of Gram-negative bacteria.
In the final report, the research team concluded, "CHX and intracanal medication used were able to eliminate the microorganisms from the root canal; the endotoxins were reduced, yet not completely eliminated".
These results strongly suggested that ginger bioactive compound processes a significant antibacterial activity, particularly in those of C. albicans.
Taken together, there is no doubt that ginger may be considered a functional food for the prevention and combined with primary medicine for the treatment of yeast infection with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-Candida and radical scavenging activities of essential oils and oleoresins of Zingiber officinale Roscoe and essential oils of other plants belonging to the family Zingiberaceae by Takahashi M1, Inouye S, Abe S.(PubMed)
(2) Action of Chlorhexidine, Zingiber officinale, and Calcium Hydroxide on Candidaalbicans, Enterococcus faecalis, Escherichia coli, and Endotoxin in the Root Canals by Valera MC1, Oliveira SA2, Maekawa LE2, Cardoso FG3, Chung A2, Silva SF2, Carvalho CA2. (PubMed)
(3) Inflammation and gastrointestinal Candida colonization by Carol A. Kumamoto. (PMC)
#Healthyfood #Fennels Exhibit Anti-antispasmodic Activity, According to Studies
By Kyle J. Norton
Fennel may have a potential and positive effect in reducing pain through its anti-antispasmodic property, some scientists suggested.
Anti-antispasmodic activity is an action that relieves, prevents, or lowers the incidence of muscle spasms, especially those of adnominal muscle in the uterus and smooth muscle such as in the bowel wall.
Certain hormones that have the function of controlling muscle contraction and relaxation are found to associate with the intensity of muscle spasms, if overexpressed.
Fennel (Foeniculum vulgare) is a plant species of the genus, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The herb has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle, and relieve PMS,...
In the findings, the natural antispasmodic ingredients with little or no side effects, Dr. Shamkant B. Badgujar, and colleagues launched an investigation to compare doses of 2.5 and 10.0 mL/L of an alcoholic extract with other Germanic medicinal plants, including Melissa officinalis, Rosmarinus officinalis, Mentha piperita, Matricaria chamomilla, Carum carvi, and Citrus aurantium.
The experiment was carried out on guinea pig ileum by using acetylcholine and histamine as spasmogens.
After taking into all account co and confounders account, researchers found that application-tested doses of alcoholic extract of the fruits of Foeniculum vulgare exert a significant anti-antispasmodic activity by inhibiting the acetylcholine and histamine-induced guinea pig ileal contractions.
Further analysis of the effects of n essential oil obtained from the fruits of Foeniculum vulgare at the doses of 25 μg/ and 10 μg/mL, researchers discovered that the injections also demonstrated a similar as of the extract but through the inhibition of the hormone oxytocin and prostaglandin activities.
Oxytocin and prostaglandin are hormones with a function that causes the contraction of the muscles of the uterus. Over contraction of muscles of the uterus is a major cause of abdominal pain in women.
Additionally, the comparison of the antispasmodic property of 4 different herbal medicine that has been used in traditional medicine for the treatment of abdominal pain in Swiss mice, including fennel according to the guidelines of the Organization for Economic Co-operation and Development (OECD) also found that all herbs used in the testing display a substantial reduction of abdominal pain without inducing any adverse effects.
In the experiment carried out on the guinea pig, the application of fennel also showed significant relaxation in different agonists like histamine and acetylcholine-induced contractions in guinea-pig ileum.
Interestingly, in the study to investigate whether oral fennel drop has any effects on primary dysmenorrhea, the occurrence of painful menstrual cramps of the uterus, researchers conducted an experiment on sixty college students who suffer from primary dysmenorrhea.
The participants were randomly assigned to two groups and followed up for two cycles. The treatment group was given fennel drop and the control group was given non-steroidal anti-inflammatory drugs (NSAIDs) or oral contraceptive pills.
After assessing the final report, researchers suggested that both groups exert a clinically significant effect in reducing pain. However, a comparison of bleeding severity in the study group before and after the intervention on the first day, second day, third day, fourth day, and fifth day was 0.948, 0.330, 0.508, 0.583, and 0.890, respectively.
Dr. Bokaie M, the lead scientist said, "Fennel can be effective in reducing the severity of dysmenorrhea, but it has an unpleasant taste in view of most of the volunteers".
Taken all together, fennel may be considered a secondary and therapeutical form of treatment in reducing pain caused by the overexpression of hormones that control muscle contraction through its antispasmodic activity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) Spasmolytic effect of traditional herbal formulation on guinea pig ileum by Kumar D1, Ganguly K1, Hegde HV1, Patil PA2, Kholkute SD1(PubMed)
(3) Oral fennel (Foeniculum vulgare) drop effect on primary dysmenorrhea: Effectiveness of herbal drug by Bokaie M1, Farajkhoda T, Enjezab B, Khoshbin A, Karimi-Zarchi M(PubMed)
Fennel may have a potential and positive effect in reducing pain through its anti-antispasmodic property, some scientists suggested.
Anti-antispasmodic activity is an action that relieves, prevents, or lowers the incidence of muscle spasms, especially those of adnominal muscle in the uterus and smooth muscle such as in the bowel wall.
Certain hormones that have the function of controlling muscle contraction and relaxation are found to associate with the intensity of muscle spasms, if overexpressed.
Fennel (Foeniculum vulgare) is a plant species of the genus, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The herb has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle, and relieve PMS,...
In the findings, the natural antispasmodic ingredients with little or no side effects, Dr. Shamkant B. Badgujar, and colleagues launched an investigation to compare doses of 2.5 and 10.0 mL/L of an alcoholic extract with other Germanic medicinal plants, including Melissa officinalis, Rosmarinus officinalis, Mentha piperita, Matricaria chamomilla, Carum carvi, and Citrus aurantium.
The experiment was carried out on guinea pig ileum by using acetylcholine and histamine as spasmogens.
After taking into all account co and confounders account, researchers found that application-tested doses of alcoholic extract of the fruits of Foeniculum vulgare exert a significant anti-antispasmodic activity by inhibiting the acetylcholine and histamine-induced guinea pig ileal contractions.
Further analysis of the effects of n essential oil obtained from the fruits of Foeniculum vulgare at the doses of 25 μg/ and 10 μg/mL, researchers discovered that the injections also demonstrated a similar as of the extract but through the inhibition of the hormone oxytocin and prostaglandin activities.
Oxytocin and prostaglandin are hormones with a function that causes the contraction of the muscles of the uterus. Over contraction of muscles of the uterus is a major cause of abdominal pain in women.
Additionally, the comparison of the antispasmodic property of 4 different herbal medicine that has been used in traditional medicine for the treatment of abdominal pain in Swiss mice, including fennel according to the guidelines of the Organization for Economic Co-operation and Development (OECD) also found that all herbs used in the testing display a substantial reduction of abdominal pain without inducing any adverse effects.
In the experiment carried out on the guinea pig, the application of fennel also showed significant relaxation in different agonists like histamine and acetylcholine-induced contractions in guinea-pig ileum.
Interestingly, in the study to investigate whether oral fennel drop has any effects on primary dysmenorrhea, the occurrence of painful menstrual cramps of the uterus, researchers conducted an experiment on sixty college students who suffer from primary dysmenorrhea.
The participants were randomly assigned to two groups and followed up for two cycles. The treatment group was given fennel drop and the control group was given non-steroidal anti-inflammatory drugs (NSAIDs) or oral contraceptive pills.
After assessing the final report, researchers suggested that both groups exert a clinically significant effect in reducing pain. However, a comparison of bleeding severity in the study group before and after the intervention on the first day, second day, third day, fourth day, and fifth day was 0.948, 0.330, 0.508, 0.583, and 0.890, respectively.
Dr. Bokaie M, the lead scientist said, "Fennel can be effective in reducing the severity of dysmenorrhea, but it has an unpleasant taste in view of most of the volunteers".
Taken all together, fennel may be considered a secondary and therapeutical form of treatment in reducing pain caused by the overexpression of hormones that control muscle contraction through its antispasmodic activity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) Spasmolytic effect of traditional herbal formulation on guinea pig ileum by Kumar D1, Ganguly K1, Hegde HV1, Patil PA2, Kholkute SD1(PubMed)
(3) Oral fennel (Foeniculum vulgare) drop effect on primary dysmenorrhea: Effectiveness of herbal drug by Bokaie M1, Farajkhoda T, Enjezab B, Khoshbin A, Karimi-Zarchi M(PubMed)
Bilberry, The Herbal Medicine in Reducing the Risk of #CardiovascularDisease (#CVD), Researchers Suggest
By Kyle J. Norton
Cardiovascular disease is a general term for diseases associated with the blood vessels and heart, including coronary artery diseases (CAD) affected by obstruction of arteries and stroke-affected by the capillaries in the brain.
In other words, the disease in CVD is vary depending on the affected locations. Atherosclerosis is also the most common cause of cardiovascular disease.
The exact causes of CVD are not clear. However, high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, are found to be associated with an increased risk of CVD.
According to the statistics provided by the American Heart Association, over 84 million people in the US suffer from some form of cardiovascular disease, causing the death of 2,200 people a day.
Sadly, approximately 15 million U.S. adults have coronary heart disease.
Out of many risk factors, some researchers suggested that high blood pressure found in 103 million U.S. adults one of the major causes of CVD. Believe it or not, approximately 54% of strokes and 47% of coronary heart diseases, worldwide, are attributable to high blood pressure.
Dr. Chen-Yi Wu, the lead scientist said, "The cardiovascular and expanded-cardiovascular mortality risks were lowest when systolic blood pressures were 120 to 129 mm Hg, and increased significantly when systolic blood pressures (SBPs) were ≥160 mm Hg or diastolic BPs were ≥90 mm Hg".
And, " The impacts of stage 2–3 hypertension on mortality risks were significantly increased among women. The mortality risks of hypertension were not attenuated with older age".
Bilberry is a species of low-growing shrub in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as an herb in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer,
In the urgency to find a natural ingredient for the prevention of cardiovascular diseases (CVD), a leading cause of death researchers examined the bilberry's beneficial effects on CVD risk reduction.
The study included women (n=25) and men (n=11) who consumed 150 g of frozen stored bilberries 3 times a week for 6 weeks.
According to the tested assays, consumption of bilberries showed a decrease in total cholesterol, LDL-C, TG, glucose, albumin, γ-glutamyltransferase, and a positive increase in HDL-C.
All parameters associated with the risk of CVD were decreased substantially at the end of the study. In other words, bilberry reduced the risk of CVD by promoting the blood flow to the heart and other parts of the body.
Interestingly, in men, favorable changes were observed in total cholesterol, glucose, albumin, aspartate aminotransferase, γ-glutamyltransferase, and HDL-C compared to women.
The results strongly support the regular use of bilberries as a dietary source of fruit to reduce the CVD risk, by decreasing LDL-C/TG and increasing HDL-C.
Dr. Habanova M, after taking into account co and confound wrote in the final report, "Changes in other parameters were not significant, for both women and men. Thus, the regular intake of bilberries can be important to reduce CVDs risk, by decreasing LDL-C/TG and increasing HDL-C".
Taken altogether, bilberry may be considered a functioning remedy for the prevention of cardiovascular diseases (CVD), pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Intake of bilberries (Vaccinium myrtillus L.) reduced risk factors for cardiovascular disease by inducing favorable changes in lipoprotein profiles by Habanova M1, Saraiva JA2, Haban M3, Schwarzova M4, Chlebo P5, Predna L6, Gažo J7, Wyka J. (PubMed)
(2) A Brief Review of Blue- and Bilberries' Potential to Curb Cardio-Metabolic Perturbations: Focus on Diabetes by Crespo MC1, Visioli F. (PubMed)
(3) High Blood Pressure and All-Cause and Cardiovascular Disease Mortalities in Community-Dwelling Older Adults by Chen-Yi Wu, MD, Ph.D., Hsiao-Yun Hu, Ph.D., Yiing-Jenq Chou, MD, Ph.D., Nicole Huang, Ph.D., Yi-Chang Chou, MS, and Chung-Pin Li, MD, Ph.D. (PMC)
Cardiovascular disease is a general term for diseases associated with the blood vessels and heart, including coronary artery diseases (CAD) affected by obstruction of arteries and stroke-affected by the capillaries in the brain.
In other words, the disease in CVD is vary depending on the affected locations. Atherosclerosis is also the most common cause of cardiovascular disease.
The exact causes of CVD are not clear. However, high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, are found to be associated with an increased risk of CVD.
According to the statistics provided by the American Heart Association, over 84 million people in the US suffer from some form of cardiovascular disease, causing the death of 2,200 people a day.
Sadly, approximately 15 million U.S. adults have coronary heart disease.
Out of many risk factors, some researchers suggested that high blood pressure found in 103 million U.S. adults one of the major causes of CVD. Believe it or not, approximately 54% of strokes and 47% of coronary heart diseases, worldwide, are attributable to high blood pressure.
Dr. Chen-Yi Wu, the lead scientist said, "The cardiovascular and expanded-cardiovascular mortality risks were lowest when systolic blood pressures were 120 to 129 mm Hg, and increased significantly when systolic blood pressures (SBPs) were ≥160 mm Hg or diastolic BPs were ≥90 mm Hg".
And, " The impacts of stage 2–3 hypertension on mortality risks were significantly increased among women. The mortality risks of hypertension were not attenuated with older age".
Bilberry is a species of low-growing shrub in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as an herb in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer,
In the urgency to find a natural ingredient for the prevention of cardiovascular diseases (CVD), a leading cause of death researchers examined the bilberry's beneficial effects on CVD risk reduction.
The study included women (n=25) and men (n=11) who consumed 150 g of frozen stored bilberries 3 times a week for 6 weeks.
According to the tested assays, consumption of bilberries showed a decrease in total cholesterol, LDL-C, TG, glucose, albumin, γ-glutamyltransferase, and a positive increase in HDL-C.
All parameters associated with the risk of CVD were decreased substantially at the end of the study. In other words, bilberry reduced the risk of CVD by promoting the blood flow to the heart and other parts of the body.
Interestingly, in men, favorable changes were observed in total cholesterol, glucose, albumin, aspartate aminotransferase, γ-glutamyltransferase, and HDL-C compared to women.
The results strongly support the regular use of bilberries as a dietary source of fruit to reduce the CVD risk, by decreasing LDL-C/TG and increasing HDL-C.
Dr. Habanova M, after taking into account co and confound wrote in the final report, "Changes in other parameters were not significant, for both women and men. Thus, the regular intake of bilberries can be important to reduce CVDs risk, by decreasing LDL-C/TG and increasing HDL-C".
Taken altogether, bilberry may be considered a functioning remedy for the prevention of cardiovascular diseases (CVD), pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Intake of bilberries (Vaccinium myrtillus L.) reduced risk factors for cardiovascular disease by inducing favorable changes in lipoprotein profiles by Habanova M1, Saraiva JA2, Haban M3, Schwarzova M4, Chlebo P5, Predna L6, Gažo J7, Wyka J. (PubMed)
(2) A Brief Review of Blue- and Bilberries' Potential to Curb Cardio-Metabolic Perturbations: Focus on Diabetes by Crespo MC1, Visioli F. (PubMed)
(3) High Blood Pressure and All-Cause and Cardiovascular Disease Mortalities in Community-Dwelling Older Adults by Chen-Yi Wu, MD, Ph.D., Hsiao-Yun Hu, Ph.D., Yiing-Jenq Chou, MD, Ph.D., Nicole Huang, Ph.D., Yi-Chang Chou, MS, and Chung-Pin Li, MD, Ph.D. (PMC)
Subscribe to:
Posts (Atom)