Cruciferous Vegetables May Process Anti Inflammatory Activity, According to Studies

By Kyle J. Norton

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management, and treatment of diseases has induced much interest in today renowned scientists.
But many researchers have raised questions of herbal quality, because geographic differences, time of grown and harvest, etc. may affect their's potency. I do believe, these questions can only be answered by experienced herbalists.

Intake of cruciferous vegetables may be inversely correlated with circulating proinflammatory levels in women.

In a total of 1,005 middle-aged Chinese women study, consumption of cruciferous vegetables regularly is associated to lower circulating concentrations of proinflammatory cytokines.

Proinflammatory cytokines, also known as Interleukin (IL) and tumor necrosis factor (TNF), secreted by the immune system to protect our body in inducing fever, inflammation, tissue destruction, etc.


Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli, etc.

Further to the study, Sulforaphane (SFN) and Diallyl disulfide(DAFDs), the naturally occurring isothiocyanate found in cruciferous vegetables, in the highly metastatic B16F-10 melanoma cells exhibited the induction of apoptosis in the cancer cell line, through the involvement of proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin.

Dr. Pratheeshkumar P, the lead author of the study suggested, DADS induces caspase-dependent apoptosis through an induced cell death pathway in B16F-10 melanoma cells by activating...... and suppressing pro-inflammatory cytokines.

Other phytochemicals found in the vegetables, such as 3,3'-diindolylmethane (DIM), a derivative of indole-3-carbinol, also expressed anti-pro-inflammatory effects through interleukin (IL)-1beta, IL-6, and tumor necrosis factor.

 
In fact, chemical compounds found in the vegetable, not only inhibited the pro-inflammatory cytokines in the expression of chronic diseases and cancers but also involved in other aspects, such as environmental airborne particulate pollutants, according to the East Campus - Laurentian University.


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Sources
(1) Cruciferous vegetable intake is inversely correlated with circulating levels of proinflammatory markers in women by Jiang Y, Wu SH, Shu XO, Xiang YB, Ji BT, Milne GL, Cai Q, Zhang X, Gao YT, Zheng W, Yang G.(PubMed)
(2) Induction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells by Hamsa TP1, Thejass P, Kuttan G.(PubMed)
(3) The role of mitochondria-mediated intrinsic death pathway in gingerdione derivative I6-induced neuronal apoptosis by Lin CH1, Chen PS, Kuo SC, Huang LJ, Gean PW, Chiu TH.(PubMed)
(4) Oral administration of 3,3'-diindolylmethane inhibits lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice by Kim EJ1, Shin M, Park H, Hong JE, Shin HK, Kim J, Kwon DY, Park JH.(PubMed)
(5) Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract by Ritz SA1, Wan J, Diaz-Sanchez D.(PubMed)

Queen Herb, Chaste Tree Berry May Process Anti-Aging Chronic Diseases Activity, Researchers Find

By Kyle J. Norton

Chaste tree berry may process a strong effect in reduced the risk of free radical progression in inducing various diseases, the renowned institute suggested.

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.

Antioxidants are chemical compounds with the function of inhibited oxidation caused by the production of free radicals with an aim to reduce the risk of oxidative damage to our body.

According to the Faculty of Pharmacy, Ege University, in the observation of the chemical activity of different preparation s of Chaste tree berry, researchers showed that water and ethanol extract content is far stronger antioxidant activity in compared n-hexane extracts.

In vitro antioxidant assays, the newly differentiated ingredients isolated from the Chaste tree berry, EtOAc extract displayed a significant antioxidant property in reduced free radicals caused by brain homogenate. at the concentration-dependent effect tested by 1,1-diphenyl-2-picrylhydrasyl (DPPH) free radical assay (IC(50) = 68 microg/mL) in compared fractions of MeOH-H(2)O and n-hexane fraction.


The study also suggested that the efficacy of antioxidant effect in the extract may have resulted from the recently discovered phytochemicals, flavonoid constituents EtOAc extract, casticin, vitexin, and orientin as viewed in the tested essay.


More importantly, in support of the above differentiation, a study of mice subcutaneously injected with d-galactose (500 mg/kg/d for 45 days) induced aging and natural aging. administrated extract of Vitex (600 mg/kg/bid for 7 days by gavage) to 72 female NMRI mice (48 3-month-old normal mice and 24 18-24-month-old mice), weighing 30-35 g randomly divided into six groups: control, Vitex, d-galactose, Vitex + d-galactose, Aging, and Vitex + Aging, groups treated with chaste tree berry expressed a superior effect in restored estrous cycle and damage of uterus and ovarian tissues, through antioxidant activities in ameliorated oxidative stress and aging diseases.

Truly, mice treated with extract of Chaste tree berry only showed a reduced presence of free radicals but also improved hormone expression in natural and d-galactose induced aging.

Taking together, there is no doubt that Chaste tree berry displayed a significant antioxidant potential in ameliorated the risk of free radicals in induced chronic diseases, but a large amount of intake should be taken with care.


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Sources
(1) Antioxidant activity of Vitex agnus-castus L. extracts by Sağlam H1, Pabuçcuoğlu A, Kivçak B.(PubMed)
(2) Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents by Hajdú Z1, Hohmann J, Forgo P, Martinek T, Dervarics M, Zupkó I, Falkay G, Cossuta D, Máthé I.(PubMed)
(3) Effects of Vitex agnus-castus fruit on sex hormones and antioxidant indices in a d-galactose-induced aging female mouse model by Ahangarpour A1, Najimi SA2, Farbood Y3.(PubMed)

Healthy Foods Dried Peas and Dried Beans Ameliorate the Risk and Treatment of Colon Cancer in Vivo and Human Studies

By Kyle J. Norton

Dietary factors can influence cancers formation and growth, intake of dried peas may have a potential effect in reduced risk of colon cancer, a recent study suggested

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with a healthy source of proteins, fibers, vitamins, and minerals.

Colon cancer is a condition characterized by cell growth disorderly and irregularly in the tissues of the colon.

A case-control designed study of 186 men and women with a mean of 58 years of age revealed that consumption of legumes such as dried beans, split peas, or lentils daily and regularly was inversely associated with reduced risk of colon cancer, after adjusting all potential confounding variables.

The relative risk odd ratio of colon cancer occurrence in these subjects was ameliorated substantially in comparison to control.


Researchers also indicated that the risk of colon cancer decrease may be attributed to legumes dietary fiber together with enormous presences of phytochemical compounds.
Dr. Agurs-Collins T, the led author said, "Nurses working with African-Americans should encourage consumption of these foods to decrease this risk".

Others, in the study of the same subject, suggested that by modifying diet and lifestyle habits, adenomatous polyps and 25-35% of colon adenoma risk could be avoidable. As consumption of legumes at least 3 times/wk reduced the risk of colon cancer by 33% after adjusting for meat intake.

Furthermore, the research result also postulated that a high frequency of consumption of cooked green vegetables, dried fruit, legumes, and brown rice was associated with a decreased risk of colorectal polyps.

Interestingly, in the investigated effect of consumption of standard diets supplemented with freeze-dried vegetables (peas, spinach, sprouts, and broccoli) and carotenoids (all-trans beta-carotene and palm oil carotenoid extract) on surrogate end-point markers for colorectal cancer in an azoxymethane-induced rat model, researchers at the Unilever Research Vlaardingen, illustrated that
peas, spinach, sprouts, and a mix of all vegetable diet expressed a significantly reduced the number of foci with >2 aberrant crypts/focus by 37, 26, 23, and 26%, particularly in the pea and spinach intervention groups.


After adjusting to other risk factors, researchers filed the following reports
1. Peas, spinach, sprouts, and a mix of all vegetable diet was beneficial effects in reduced risk of colorectal carcinogenesis
2. Consumption of several types of vegetables inhibits the early onset of colorectal carcinogenesis
3. and suggest that the vegetable-induced effect is more pronounced in advanced lesions.

Taking all together, dried peas may be used as therapeutic ingredients in reduced risk and treatment of colon cancer and diseases related to colon abnormalities.


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Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.




Sources
(1) Legume intake and reduced colorectal adenoma risk in African-Americans by Agurs-Collins T1, Smoot D, Afful J, Makambi K, Adams-Campbell LL(PubMed)
(2) Foods and food groups associated with the incidence of colorectal polyps: the Adventist Health Study by Tantamango YM1, Knutsen SF, Beeson WL, Fraser G, Sabate J.(PubMed)
(3) Effect of vegetable and carotenoid consumption on aberrant crypt multiplicity, a surrogate end-point marker for colorectal cancer in azoxymethane-induced rats by Rijken PJ1, Timmer WG, van de Kooij AJ, van Benschop IM, Wiseman SA, Meijers M, Tijburg LB.(PubMed)

Green Tea Decoction GTD (2/3 Epigallocatechin Gallate (EGCG)+1/3 Epigallocatechin EGC) Reduces Weight Gain and Promotes Weight Loss, Researchers Say

Kyle J. Norton 

Green tea polyphenols may have a therapeutic effect in reduced weight gain through decreased hormone expression with function direct influence of excess energy deposit, some scientists opinionated.

Green tea, a precious drink processes numbers of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

Weight gain is an increase in body weight, involved an increase in muscle mass, fat deposits, excess fluids.

In the compared green tea, polyphenols [epigallocatechin gallate (EGCG), epigallocatechin (EGC)] in a decoction of green tea leaves versus usual green tea extracts to evaluate the effect in weight gain in obese animal models fed with a high-fat diet, researchers after taking into account of other con-founders suggested that green tea decoction acute administration of GTD with 2/3 EGCG+1/3 EGC inhibited SGLT-1 activity involved distinct and complementing glucose homeostasis through absorbing glucose from the diet in the small intestine and by reabsorbing the filtered glucose in the tubular system of the kidney, thus reducing access energy being converted to glycogen or fat and deposit in liver, muscles and fat cells.

Additionally, green tea decoction not only improved glucose tolerance but also demonstrated a significant increase in GLUT2 protein in facilitated glucose movement across cell membranes in the regulation of glucose absorption in the distribution of dietary sugar to tissues to induce calorie restriction.

Chronic administration of green tea decoction GTD for 6 weeks, in the same experiment models, also displayed a huge reduction of body weight gain, circulating triglycerides and cholesterol, and improved glucose tolerance, through significantly reduced SGLT-1 as seen in an acute application and increased GLUT2 mRNA levels in the jejunum mucosa with function in increase the surface area of tissue available to absorb nutrients from ingested foodstuffs for decreased fat accumulation and glucose in the liver.


Dr. Snoussi C, the lead author said, "GTD-treated rats for 6 weeks display significantly reduced SGLT-1 and increased GLUT2 mRNA levels in the jejunum mucosa". This result showed that green tea decoction with polyphenols such as epigallocatechin gallate (EGCG), epigallocatechin (EGC) may have a certain effect in reduced weight gain through decreased fat deposit in the liver and promoted calorie restriction.

Further analysis of C57BL/6J mice fed a high-fat/high-sucrose diet (HF/HS, 32% energy from fat; 25% energy from sucrose) or the same diet supplemented with 0.25% GTP or BTP or a low-fat/high-sucrose (LF/HS, 10.6% energy from fat, 25% energy from sucrose) diet for 4 weeks showed that treatment with decaffeinated green tea (GT) polyphenols inhibited weight gain in mice fed an obesogenic diet as indicated above, through the rearrange the relative proportions of Blautia, Bryantella, Collinsella, Lactobacillus, Marvinbryantia, Turicibacter, Barnesiella, and Parabacteroides is correlated with weight loss by a decrease of cecum Firmicutes and increase in Bacteroidetes in the gastrointestinal tract.
Indeed, GTP not only induces weight loss in association with alteration of the gut microbiota but also increased hepatic AMPK in reaction in sugar metabolism, and energy storage and release.

Interestingly, according to the START Clinic for the Mood and Anxiety Disorders, oral administration of green tea extract induced an unexpected decrease in total body fat mass, a decrease in body fat percentage, and an increase in lean body mass in patients with weight gain induced by psychotropic medications.


Taken together, green tea, bioactive active polyphenols epigallocatechin gallate (EGCG), epigallocatechin (EGC) may be used as a functional food in reduced weight gain induced by all sources and increased weight loss through regulation of energy metabolism in fat accumulation.


For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal of Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Decaffeinated green and black tea polyphenols decrease weight gain and alter microbiome populations and function in diet-induced obese mice by Henning SM1, Yang J2, Hsu M2, Lee RP2, Grojean EM2, Ly A2, Tseng CH3, Heber D2, Li Z2. (PubMed)
(2) Green tea decoction improves glucose tolerance and reduces weight gain of rats fed a normal and high-fat diet by Snoussi C1, Ducroc R2, Hamdaoui MH3, Dhaouadi K4, Abaidi H3, Cluzeaud F2, Nazaret C2, Le Gall M2, Bado A5. (PubMed)
(3) Weight gain and psychiatric treatment: Is there a role for green tea and conjugated linoleic acid? by Katzman MA1, Jacobs L, Marcus M, Vermani M, Logan AC. (PubMed)

Herbal Anise's Anethole Reduces the Risk, Progression and Treatment of Osteoporosis, Scientists Suggest

Kyle J. Norton


Anise may have a potential and substantial effect in reduced risk and progression and treatment of osteoporosis, some scientists suggested.

Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belongings to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic,...

Chemical constituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.

In the investigation of the herbal selective estrogen receptor modulators or SERMs effect in risk of osteoporosis, in comparison of plant aqueous extracts derived from Greek flora (Sideritis euboea, Sideritis clandestina, Marticaria chamomilla, and Pimpinella anisum), researchers at the Medical School, University of Athens found that all extracts exert profound activities in stimulated the differentiation and mineralization of osteoblastic cell culture.

Further analysis, also discovered that all plant extracts at concentration range 10-100 microg/mL, including Anise induced osteoblastic cell differentiation in formation of bone and improved bone density.

These results indicated that Anise and other plant extracts may comprise a substantial anti-estrogenic effect in reduced risk of osteoporosis in a dose-dependent manner.


Also, in the evaluation of (E)-anethole, a major bioactive compound isolated from Anise protective effect on H2O2-induced alterations in collagen metabolism, researchers showed that application of anethole of 0.5 µM for 1 h completely prevent the alternation of cells treated with 300 µM H2O2 in displayed a decrease in collagen biosynthesis of 54 %, correlated with alterations of type I collagen mRNA expression in the osteoblasts in initiated higher bone turn over.


Additionally, differentiation also revealed that Anise anethole administration at 10 µM, exerts the most efficient suppression in the ameliorated expression of MMP-2 and MMP-9 caused by H2O2 induced alterations in collagen metabolism, in contributing to the 8 % decrease in the amount of collagen secreted into the medium.

The result suggested that the application of H2O2 not only directly activates MMPs but also causes a decrease in the expression of their inhibitors, such as TIMP2, a metastasis suppressor in initiated alterations of collagen metabolism in bone.

In Other words, anethole isolated from Anise attenuated ROS causes increased activity of matrix metalloproteinases (MMPs) in degraded collagen in fibroblasts.
Some researchers suggested, "the loss of MMP-9 improved the connectivity density of the trabeculae, whereas the loss of MMP-2 reduced this parameter. Similar differential effects in architecture were observed in the L5 vertebra, but bone volume fraction was lower for both MMP-2 and MMP-9 (in mice study) "


Taken together, Anise and its bioactive anethole may be considered as a functional herb for reduced risk and treatment of osteoporosis caused by collagen loss in skin and bone. However, intake of Anise supplement should be taken with extreme care in prevented toxicity.

For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal of Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties by Kassi E1, Papoutsi Z, Fokialakis N, Messari I, Mitakou S, Moutsatsou P.(PubMed)
(2) Anethole prevents hydrogen peroxide-induced apoptosis and collagen metabolism alterations in human skin fibroblast by Anna Galicka, Rafał Krętowski, Jolanta Nazaruk, and Marzanna Cechowska-Pasko(PubMed)
(3) Differential Effects Between the Loss of MMP-2 and MMP-9 on Structural and Tissue-Level Properties of Bone by Jeffry S Nyman,1,2,3,4 Conor C Lynch,5 Daniel S Perrien,2,3 Sophie Thiolloy,6 Elizabeth C O’Quinn,2,7 Chetan A Patil,4 Xiaohong Bi,2,4 George M Pharr,8,9 Anita Mahadevan-Jansen,4 and Gregory R Mundy(PMC)
(4) Osteoporosis, a unitary hypothesis of collagen loss in skin and bone by Shuster S1.(PubMed)

Mixture of Kale (Brassica Oleracea) and Payapa Shows Promising Results for the Treatment of Colitis in Vivo

By Kyle J. Norton

Colitis is medical a condition characterized by the inflammation of the large intestine, including the colon, caecum, and rectum.

There is no exact cause of colitis. Certain risk factors such as colon infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis have been found to increase the risk of the onset of the condition.

The most common symptoms of colitis are totally depending on the types, including abdominal pain, cramping, diarrhea, with or without blood in the stool.

Types of colitis according to the Catholic University of the Sacred Heart, are including
Depending on the causes, colitis can be classified into microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis, and Behcet's colitis, particularly in those associated with inflammatory bowel disease (IBD), such as ulcerative colitis (UC).

Some cases of colitis are also induced by the overactive immune system in the response of unharmful allergens.

Most common symptoms of colitis depending on the cause of the disease, including abdominal pain, cramping, diarrhea, with or without blood in the stool.

Some patients in the early phase of colitis may also experience symptoms of fever, chills, fatigue, and skin inflammation.

If you experience some of the aforementioned symptoms, please make sure that you check with your doctor to rule out the possibility.

Treatment of colitis is totally depending on the causes. Infected colitis is treated with antibiotics. 

However, treatment of non-infection colitis is focusing on symptoms relief, supportive care, and maintaining adequate hydration and pain control.

If you are taking antibiotics for the treatment of colitis, please discuss the side effect with your doctor.

Kale is a species of Brassica Oleracea, belonging to the family Brassicaceae, native to coastal southern and western Europe. Since kale's leave is highly nutritious and easy to grow with a range of long season from the middle of winter through the beginning of spring, it is cultivated as foods in most parts of Europe.

On finding a potential wholefood for the treatment of colitis researchers examined the evaluate the effect of dried vegetables as a prebiotic and as an intestinal anti-inflammatory in the rat colitis model.

Rats selected to the study were given orally, 500 mg/kg of rat weight of three treatments of dried vegetables: papaya, kale and the mixture of both vegetables (60% of kale plus 40% of papaya) with colitis were induced by intracolonic administration of trinitrobenzene sulfonic acid (TNBS) after the two weeks of treatment.

According to the prebiotic assay, administration of the mixture showed to modulate the bacterial flora in both the healthy rats and rats with colitis induced by TNBS compared to the veggie individual treatment

Furthermore, the application of the mixture showed a strong intestinal anti-inflammatory effect in the colitic rats observed by the reduced levels of pro-inflammatory colonic iNOS, TNFa and IL-1b  expression

Taken altogether, kale used a combination with  papaya may be considered a mixture for the treatment of colitis




Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of kale and papaya supplementation in colitis induced by trinitrobenzenesulfonic acid in the rat Cibele Lima de Albuquerque a,*, Monica Comlada b , Desiree Camuesco b , Maria Elena Rodrı´guez-Cabezas b , Anderson Luiz-Ferreira a , Ana Nieto c , Alba Regina Monteiro de Souza Brito a , Antonio Zarzuelo b , Julio Ga´lvez. (EL SEVIER)

Phytochemical Omega -3 Fatty Acids Process Anti-Hyperglycemic Activity, According to Studies

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.

Although hyperglycemia is a hallmark in patients with diabetes, the condition can also occur to people without diabetes due to a certain medical condition such as pneumonia in the elderly.

Most cases of hyperglycemia occurred in patients who do not manage diabetes properly.

Untreated hyperglycemia has been found to induce ketoacidosis characterized by the symptoms shortness of breath, breath that smells fruity and gastrointestinal discomforts such as nausea, vomiting, and dry mouth.

Ketoacidosis is a life-threatening condition caused by your body's inability to make enough insulin.

The most common causes of hyperglycemia are associated with an uncontrolled diet, improper use of insulin and skip diabetic medication.

The most common symptoms of hyperglycemia are increased thirst frequent urination, fatigue (weak, and unintended weight loss. In severe cases, some patients may also experience symptoms of headaches, trouble concentrating and blurred vision.

Most cases of hyperglycemia can be controlled by the following diabetes guidance.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of diabetic complications, researchers examined a combination of plant sterols (PS) and omega-3 fatty acids synergistic effect on impaired glucose regulation (IGR).

A total of 200 participants were randomized to receive PS and omega-3 fatty acids (n = 50), PS alone (n = 50), omega-3 fatty acids alone (n = 50), or placebo soybean powder plus placebo capsules (n = 50) for 12 weeks. 

According to the results of the experiment, 

* Compared to the placebo group, the group receiving the combined intervention exhibited significantly decreased TG, HDL-C, fasting plasma glucose (FPG), Insulin Resistance (HOMA-IR)) and glycosylated hemoglobin (HbA1c).

* Omega-3 fatty acids alone were associated with significant reductions in waistline, TG, FBG, HOMA-IR, and Hs-CRP.

* The combined ap[plication also exerted no significant changes in body weight, BMI, blood pressure, FINS, body fat percentage, visceral fat rating, TC, LDL-C or IL-6.

Based on the findings, researchers said, " this study has demonstrated for the first time that PS, omega-3 fatty acids or the combination thereof significantly improved inflammation, insulin resistance, as well as glucose and lipid metabolism in IGR individuals".

Taken altogether, Omega-3 fatty acids together with plant sterols (PS)  may be considered a supplement for the treatment of hyperglycemia-induced by IGR,  pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial by Wang JF1, Zhang HM2, Li YY1, Xia S3, Wei Y1, Yang L1, Wang D1, Ye JJ1, Li HX1, Yuan J1, Pan RR. (PubMed)