Omega-3 Fatty Shows to Reduce Cancer-Related Complications

By Kyle J. Norton

Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.

Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.

However, at the advanced stage, most cancers not can induce common symptoms such as gastrointestinal discomforts, unintended weight loss, loss of appetite and fatigue but also localized symptoms depending on the affected tissues and organs.

Cancers at this stage also can travel a distance away from the original site to induce secondary metastasis.

According to the statistics provided by the American cancer society, in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.
The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.

Compared to all cancers, lung, breast, prostate, and colorectal cancers are the most common cancer in the US.

Most common cancer complications, depending on the types of cancer are

* Pain can be caused by cancer or by cancer treatment

* Fatigue.

* Difficulty breathing. 

*Nausea. 

*Diarrhea or constipation. 

* Weight loss. 

*Chemical changes in your body. 

* Brain and nervous system problems.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the improvement of quality of life in cancer patients, researchers examined the omega-3 polyunsaturated fatty acids (PUFAs) effects on cancer complications

According to the medical literature

* A  systematic review demonstrated that a nutritional supplement enriched with fish oil decreased the symptoms of fatigue and pain in patients during chemo- and/or radiotherapy, probably due to  reduced inflammatory status.

* A recent systematic review evaluated the effects of fish oil for cachexia in advanced cancer, concluding that clinical evidence is still uncertain due to a weak methodology and a large variation of fish oil dosages. However, fish oil supplementation could benefit postoperative recovery and reduce complications, such as impaired wound healing and infections.

* The plasmatic contents of omega-6/omega-3 and ALA/EPA were associated with muscle atrophy in cachectic cancer patients, indicating that these molecules may participate in the development of cancer cachexia.

* Regarding the participation of omega-3 in cancer-associated depression, it was observed that, in newly diagnosed Japanese lung cancer patients, the ALA and total omega-3 consumption was inversely associated with the development of depression.

* The application of  omega-3 supplementation could be beneficial for hypercalcemia-associated bone resorption because it was observed that, in an animal model of apical periodontitis, omega-3 supplementation reduced bone resorption by the downregulation of the inflammatory cells influx.

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the treatment of cancer-related complications, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective Effects of Omega-3 Fatty Acids in Cancer-Related Complications by Freitas RDS1,2, Campos MM. (PubMed)

Eyebright ( Euphrasia) Demonstrates Antihyperglycemic Activity in Vivo

By Kyle J. Norton

Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.

Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.

In other words, hyperglycemia is a hallmark in patients with diabetes, the condition can also occur to people without diabetes due to a certain medical condition such as pneumonia in the elderly.

Untreated hyperglycemia has been found to induce ketoacidosis characterized by the symptoms shortness of breath, breath that smells fruity and gastrointestinal discomforts such as nausea, vomiting, and dry mouth.

Over the long-term, persistently mild hyperglycemia can lead to complications in eyes, kidneys, and nerve damage and heart disease and stroke.

Most cases of hyperglycemia can be controlled by the following diabetes guidance. 

By eating a healthy diet high in fiber, such as vegetables, fruits, nuts, legumes (beans, peas, and lentils), whole-wheat flour and wheat bran, accompanied by healthy fish, patients with type 1 and 2 diabetes can control their blood glucose without worrying the onset of hyperglycemia.

The most common causes of hyperglycemia are associated with an uncontrolled diet, improper use of insulin and skip diabetic medication.

The most common symptoms of hyperglycemia are increased thirst frequent urination, fatigue (weak, and unintended weight loss. In severe cases, some patients may also experience symptoms of headaches, trouble concentrating and blurred vision.

On finding a natural ingredient for the prevention and treatment of high blood glucose, scientists examined the effects of the aqueous extract of the leaf of Euphrasia officinale. 

Eyebright is one of the species of flowering plants, genus Euphrasia, belonging to the family Orobanchaceae, native to Europe. 

The plant has been used in traditional and herbal medicine to treat eye infection and to relieve inflammation caused by colds, coughs, sinus infections, sore throats, and hay fever.

The study included selected rats that were assigned to healthy normal or alloxan-induced diabetic rats

According to tested analysis and compared to the levels of blood glucose levels in normal and alloxan-diabetic rats

* Treatment of alloxan-induced diabetic rats showed a strong effect by bringing down the raised glucose levels,

* The extract administration exerted a significant activity against hypoglycemia in normal and diabetic induced rats.

In other words, the aqueous extract of the leaf of Euphrasia officinale. not only has a strong activity against levels of blood glucose but also ameliorated the hyperglycemia in diabetic experimental rats.

Taken altogether, Eyebright (Euphrasia)may be considered a remedy for the treatment of hyperglycemia, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antihyperglycemic activity of Euphrasia officinale leaves by Porchezhian E1, Ansari SH, Shreedharan NK. (PubMed)

Angelica Sinensis Destroys the Glioma Cells in Vitro and in Vivo

By Kyle J. Norton

A glioma is a type of brain and spinal cord tumor characterized by the alternation of DNA of the glial cells.

Believe it or not, gliomas have been found accounting for 30 percent of all brain tumors and central nervous system tumors, and 80 percent of all malignant brain tumors.

Glioma can be classified into 3 types, including
* Astrocytomas are found in glial cells, star-shaped brain cells in the cerebrum called astrocytes. Most astrocytomas are localized.

* Ependymomas are cancers that grow in your brain or any part of the spine, including your neck and upper and lower back starting from the ependymal cells in the middle of your spinal cord and fluid-filled spaces in your brain.

* Oligodendrogliomas are cancers that begin on the oligodendrocytes of the brain or from a glial precursor cell.

Primary glioblastoma is considered the most aggressive cancer that begins within the brain. Cancer may arise de novo, meaning they begin as a Grade IV tumor with no evidence.

According to the statistic, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.

Due to the rapid growth of the tumor, patients diagnosed with primary glioblastoma experience brain swelling and increased brain pressure, leading to symptoms of nausea, vomiting, and severe headaches and localized symptoms depending on the location of the tumor.

Radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.

On finding a natural ingredient for the prevention and treatment of neurological diseases, scientists examined the inhibitory effects of Angelica polysaccharides (APs), bioactive constituents of Angelica on a glioma cell line.

Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

According to tested analysis both in vitro and in vivo models,
* APs exerted a significant inhibition of the growth and proliferation of U251 cells and induced their apoptosis.

* APs effectively reduced the expression of several cell cycle regulators such as cyclins D1, B, and E in the induction of cell cycle division of the tested cell line.

* APs also inhibited the anti-apoptotic protein Bcl-2 and increased the expression of pro-apoptotic proteins Bax and cleaved-caspase-3.

* Most importantly, APs inhibited the transforming growth factor (TGF)-β signaling pathway and stimulated the expression of E-cadherin, associated with the inhibition of cell growth.

Based on the results, researchers suggest, " the results indicate that APs attenuate the tumorigenicity of glioma cells and promote their apoptosis by suppressing the TGF-β signaling pathway".

Taken altogether, Dandelion may be considered a neuroprotective remedy, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo by Zhang WF1, Yang Y1, Li X1, Xu DY1, Yan YL1, Gao Q1, Jia AL1, Duan MH. (PubMed)

Beta-Sitosterol Inhibits the Obesity- Related Chronic Inflammation

By Kyle J. Norton

Inflammation is a natural response of the immune system in the stimulation of the production of inflammatory cytokines with an aim to protect our body against infectious agents in the acute phase of bodily injury and tissue damage.

Inflammation can be acute or chronic. In the acute phase of infection, the immune system after receiving information from the neurons, macrophages, the largest white blood cells in the first line of defense stimulate the production of blood palette to cover the wound and the production of inflammatory cytokines to kill off micro-organisms, leading to symptoms of fever, redness, and swelling.

However, in many instances, overexpression of pro-inflammatory cytokines can cause cell death and tissue damage, leading to irreversible organ damage with large scars formation.

For example, overexpression of pro-inflammatory cytokines in the healing of hepatitis virus infection can lead to liver scars.

Furthermore, inflammation that lasts more than 3 months may be considered chronic inflammation, a leading cause of chronic diseases.

Chronic inflammation occurs when the immune system no longer has the ability to kill off all the infectious agents, during the onset of acute infection.

Moreover, chronic inflammation also happens in people with autoimmune disorders. In this case, the immune system attacks the bodily normal healthy tissue, by mistaking them for foreign pathogens that cause disease.

Obesity is a chronic and medical condition caused by excess body fat accumulated to some extent that impacts personal health. The hallmark of obesity is attenuated metabolism and structural cell changes in the obese fat observed by reducing metabolic activity.

According to the statistics provided by the National Center for Health Statistics (2015-2016), in the US, approximately 39.8% of adults aged 20 and over were obese accompanied by another 31.8% overweight.

Obesity is associated with a chronic inflammatory response, associated with abnormal production, pro-inflammatory cytokines observed by several biological markers.

Conditions associated with obesity-related chronic inflammation are cardiovascular diseases and metabolic syndromes, insulin resistance, type 2 diabetes, and hepatic steatosis,

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of infectious diseases, researchers elucidated the physiological roles of phytosterols in both clinical studies and animal experiments on obesity-related chronic inflammation.

According to the chemical analysis, serum sitosterol level showed a negative correlation with the expression of pro-inflammatory cytokines (IL-6 and the TNF-α) in both diabetic subjects (n=46) and non-diabetic subjects (n=178).

According to the Multiple regression analyses, ABCG5/8 hetero mice with elevated plasma sitosterol levels without any modulation of food intake fed a high-fat diet, inhibited the increase in body weight, fatty liver changes, and the expansion of perigonadal adipose tissues, compared to high fat diet-fed only ABCG5/8 hetero mice.

Furthermore, parameters associated with obese related inflammation such as the plasma IL-6 and TNF-α levels, the expressions of TNF-α and PAI-1 in the liver and the expressions of the IL-6, TNF-α, and MCP-1 levels in the adipose tissue were lower in ABCG5/8 KO mice were lower in the ABCG5/8 hetero mice with elevated plasma sitosterol.

Based on the findings, researchers said, "These results suggest that sitosterol might suppress obesity-related chronic inflammation and might be applicable to the treatment of metabolic diseases".

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of obesity-related chronic inflammation, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Sitosterol prevents obesity-related chronic inflammation by Kurano M1, Hasegawa K2, Kunimi M2, Hara M3, Yatomi Y1, Teramoto T4, Tsukamoto K. (Europe PMC)

Omega -3 Fatty Acids Induce Weight Loss Naturally in Obese with Type 2 Diabetes

By Kyle J. Norton

Today, the prevalence of extremely overweight and obese children caused by an unhealthy diet and lifestyle change over 2 decades of economic prosperity, in the southeast Asian population has raised concerns of the scientific community,

Overweight and obesity have reached epidemic proportions in many countries, affecting even younger age populations inducing an economic burden in the health care system for treatment of obesity-related disorders such as diabetes, hypertension, and cardiovascular diseases(1).


Obesity is a chronic and medical condition caused by excess body fat accumulated to some extent that impacts personal health. The hallmark of obesity is attenuated metabolism and structural cell changes in the obese fat observed by reducing metabolic activity.

Visceral fat is a layer of fat that surrounds the organs. Overexpression of visceral fat has been found to promote insulin resistance, diabetes, heart disease, and inflammation.

In obese, accumulation of visceral fat is predominant in the intra-abdominal cavity.

According to the BMI index, a person is considered overweight, if he/she has a BMI between 25 to 29.9 kg/m2. A BMI of 30 kg/m2 or more is an indication of obese.

Weight loss is a process that intentionally reduces the total body mass, through the decrease of fluid, body fat or adipose tissue or lean mass.

Due to the widespread obesity in North America (over 68% of the US population is either overweight or obese), many weight loss products were created by manufacturers. 

The weight loss products is a 66 billion business in the US, according to the statistic provided by the Marketdata LLC research firm. And the business continues to grow at a rapid rate.

Is the weight loss products worked? I don't think so. Otherwise, the percentage of the overweight population in the US should be decreased substantially.

In other words, all weight loss products may have a complex structure or a long-term commitment before the results can be seen.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic diseases associated with obesity, researchers examined the relationship between levels of serum eicosapentaenoic acid (EPA), arachidonic acid (AA), as well as EPA/AA ratio and weight loss during hospitalization in participants considered to be overweight, with type 2 diabetes.

The study included 142 patients who were hospitalized for treatment of type 2 diabetes divided into two groups depending on the achievement in the reduction of body weight 3% or more during hospitalization.

According to the tested analysis,
* After adjustment was made for several confounders, the hazard ratio of effective weight loss for logarithmical serum EPA was 1.59 (95% CI 1.02-2.49, P = 0.04) and for logarithmical EPA/AA ratio 1.64 (1.03-2.61, P = 0.04), whereas the hazard ratio for effective weight loss for logarithmical serum AA was 1.11 (0.45-2.78, P = 0.82).

* Furthermore, after dividing EPA/AA ratio and serum EPA into quartiles based on participant number, the hazard ratio for the highest quartile of EPA/AA ratio was 2.33 for the highest quartile of serum EPA 1.60 (0.80-3.19, P = 0.18) compared with the lowest quartile.

More precisely, EPA is involved in body weight change under a caloric-restriction regimen.

In other words, a high serum level of EPA, relative to the level of AA, can lead to a reduction of adipose tissue weight through the anti-inflammatory effects of EPA.

Based on the finding, researchers said, " EPA/AA ratio was found to be a better predictor of medical intervention for weight loss among overweight patients with type 2 diabetes, compared with serum EPA level".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for inducing weight loss, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Eicosapentaenoic acid/arachidonic acid ratio and weight loss during hospitalization for glycemic control among overweight Japanese patients with type 2 diabetes: a retrospective observational study by Nakanishi S1, Hirukawa H2, Shimoda M2, Tatsumi F2, Kohara K2, Obata A2, Okauchi S2, Kinoshita T2, Sanada J2, Fushimi Y2, Nishioka M2, Kan Y2, Tomita A2, Mashiko A2, Horiya M2, Iwamoto Y2, Mune T2, Kaku K3, Kaneto H. (PubMed)
(2) Rising Burden of Obesity in Asia by Ambady Ramachandran and Chamukuttan Snehalatha(Journey of Obesity)

Lycopene Processes Anti Anti Platelet Aggression Activity

By Kyle J. Norton

Platelet aggregation is a condition of platelets clumping together in the blood. In most cases, the process is to protect the vascular injury against additional bleeding and microbial pathogenic invasion.

In other words, platelet aggregation is stimulated by the first-line immune response after sensing bodily injury or damage accompanied by the production of pro-inflammatory cytokines to defend
the injured area against infection.

Platelet disorders can lead to abnormal bleeding. Most common types of genetic proposition of platelet disorders including disorder of platelet adhesion, aggregation, secretion, and procoagulant activity.

If your blood platelet count falls below the normal range from 150,000 to 450,000 platelets per microliter of circulating blood, you are considered thrombocytopenia.

Believe it or not, platelet count that falls below 10,000 platelets per microliter are dangerous. Epidemiologically, severe thrombocytopenia can be fatal.

 Most common symptoms of platelet disorders are unexplained bruising throughout the body, bleeding from your nose, mouth, or gums, under your skin, muscles, and joints and heavy or prolonged menstrual bleeding,

In severe cases, patients may also experience symptoms of vomiting blood,  blood in your feces and internal bleeding.

Conventionally, most common medication with blood-thinning activity such as aspirin (ASA) and other drugs containing aspirin non-steroidal anti-inflammatory drugs and some antibiotics may have a strong implication of the formation of platelets coagulation.

Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and perform various functions in photosynthesis.

On finding a potent ingredient for the treatment of heart disease, scientists compared the antiplatelet effect of lycopene with aspirin.

In vitro, various concentrations of Aspirin (140 μmol/L) and lycopene (4, 6, 8, 10, and 12 μmol/L) were studied against adenosine-5'- diphosphate (ADP) (2.5 μM/L) and collagen.

Based on the tested analysis, all concentrations of lycopene (4-12 μmol/L) exhibited a reduction of maximum platelet aggregation induced by aggregating agents ADP and collagen comparable with aspirin.

Furthermore, lycopene at concentration 10 μmol/L showed a maximum platelet inhibition (47.05%) of ADP, whereas lycopene at concentration 8 μmol/L showed maximum platelet inhibition (54.26%) of collagen.

In other words, lycopene protects the cardio function selectively and dose-dependently.

However, all 4 μmol/L of lycopene combined with 140 μmol/L and 70 μmol/L aspirin showed greater inhibition of platelets compared to aspirin 140 μmol/L alone, against both ADP and collagen.

Based on the findings, researchers said, "The study favorably compares lycopene and aspirin with respect to their antiplatelet activities against ADP and collagen" and "Lycopene can be considered as a potential target for modifying the thrombotic and pro-inflammatory events associated with platelet activation".

Taken altogether, lycopene found in tomato may be considered an anti-platelet aggresion phytochemical, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You.  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: An in vitro study by Sawardekar SB1, Patel TC1, Uchil D. (PubMed)
(2) Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation by Hsiao G1, Wang Y, Tzu NH, Fong TH, Shen MY, Lin KH, Chou DS, Sheu JR. (PubMed)

Leeks, The Natural Anti High Blood Cholesterol Functional Food

By Kyle J. Norton

Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.

Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.

More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.

In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).

Low-density lipoprotein is needed for our body to build cell walls, make hormones and vitamin D, and create bile salts that help you digest fat. However, overexpression of LDL can induce plaque accumulated on the arterial wall, leading to atherosclerosis, a major cause of cardiovascular disease.

Low-density lipoprotein is produced by the liver or from the dietary sources. High-density lipoprotein neutralizes the levels LDL by returning them to the liver.

Some researchers suggested that diet high in trans fats, saturated fat, sugar, smoking, medical conditions such as diabetes or high blood pressure are associated with the increased risk of high blood cholesterol.

According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.

Although there are many risk factors such as obesity, large waist circumference, physically inactive, smoking and diabetes associated with the onset of high blood cholesterol, researchers suggested that a poor diet with rich in saturated and trans fat, processed foods is the major cause of high blood cholesterol in the Western world.

Epidemiological studies indicated a healthy diet that contains a high amount of fruits and vegetables and whole-grain have a positive on blood cholesterol. In other words, hyperlipidemia can be prevented by a healthy diet.

Leek is a genius of Allium, belonging to the vegetable family vegetable Alliacaea, the same as onion and garlic. Leeks are easy to grow from seed and usually reach maturity in the autumn months, and have few pest or disease problems.

On finding a potential plant that processes anti-high blood cholesterol, researchers examined the effects of oral administration of Persian leek on plasma and liver lipids.

The study included male Syrian hamsters that were randomly divided into three groups: control (standard diet), high-fat control (high-fat/high-cholesterol diet), Persian leek (high-fat/high-cholesterol diet + 1% per weight of diet from dried powdered Persian leek) for 14 weeks.

Before treatment of a high-fat diet showed an increase of plasma and liver lipids compared to a standard diet.

Administration of Persian leek to the high-fat/high-cholesterol diet resulted in no significant changes in the concentration of the plasma lipids or liver cholesterol.

Liver triglycerides (TG), plasma Alanine aminotransferase and gene expression of tumor necrosis factor- α associated with liver stress marker and pro-inflammatory cytokines, compared to high-fat diet only.

Collectively, researchers said, "Persian leek might be considered as a herbal food that can reduce liver TG accumulation induced by high-fat diets".

Taken altogether, leeks may be considered a functional food for the prevention and treatment of high blood cholesterol, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of Persian leek (Allium ampeloprasum) on hepatic lipids and the expression of proinflammatory gene in hamsters fed a high-fat/ high-cholesterol diet by Fatoorechi V1, Rismanchi M2, Nasrollahzadeh J. (PubMed)