Beta-Sitosterol Inhibits the Obesity- Related Chronic Inflammation

By Kyle J. Norton

Inflammation is a natural response of the immune system in the stimulation of the production of inflammatory cytokines with an aim to protect our body against infectious agents in the acute phase of bodily injury and tissue damage.

Inflammation can be acute or chronic. In the acute phase of infection, the immune system after receiving information from the neurons, macrophages, the largest white blood cells in the first line of defense stimulate the production of blood palette to cover the wound and the production of inflammatory cytokines to kill off micro-organisms, leading to symptoms of fever, redness, and swelling.

However, in many instances, overexpression of pro-inflammatory cytokines can cause cell death and tissue damage, leading to irreversible organ damage with large scars formation.

For example, overexpression of pro-inflammatory cytokines in the healing of hepatitis virus infection can lead to liver scars.

Furthermore, inflammation that lasts more than 3 months may be considered chronic inflammation, a leading cause of chronic diseases.

Chronic inflammation occurs when the immune system no longer has the ability to kill off all the infectious agents, during the onset of acute infection.

Moreover, chronic inflammation also happens in people with autoimmune disorders. In this case, the immune system attacks the bodily normal healthy tissue, by mistaking them for foreign pathogens that cause disease.

Obesity is a chronic and medical condition caused by excess body fat accumulated to some extent that impacts personal health. The hallmark of obesity is attenuated metabolism and structural cell changes in the obese fat observed by reducing metabolic activity.

According to the statistics provided by the National Center for Health Statistics (2015-2016), in the US, approximately 39.8% of adults aged 20 and over were obese accompanied by another 31.8% overweight.

Obesity is associated with a chronic inflammatory response, associated with abnormal production, pro-inflammatory cytokines observed by several biological markers.

Conditions associated with obesity-related chronic inflammation are cardiovascular diseases and metabolic syndromes, insulin resistance, type 2 diabetes, and hepatic steatosis,

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of infectious diseases, researchers elucidated the physiological roles of phytosterols in both clinical studies and animal experiments on obesity-related chronic inflammation.

According to the chemical analysis, serum sitosterol level showed a negative correlation with the expression of pro-inflammatory cytokines (IL-6 and the TNF-α) in both diabetic subjects (n=46) and non-diabetic subjects (n=178).

According to the Multiple regression analyses, ABCG5/8 hetero mice with elevated plasma sitosterol levels without any modulation of food intake fed a high-fat diet, inhibited the increase in body weight, fatty liver changes, and the expansion of perigonadal adipose tissues, compared to high fat diet-fed only ABCG5/8 hetero mice.

Furthermore, parameters associated with obese related inflammation such as the plasma IL-6 and TNF-α levels, the expressions of TNF-α and PAI-1 in the liver and the expressions of the IL-6, TNF-α, and MCP-1 levels in the adipose tissue were lower in ABCG5/8 KO mice were lower in the ABCG5/8 hetero mice with elevated plasma sitosterol.

Based on the findings, researchers said, "These results suggest that sitosterol might suppress obesity-related chronic inflammation and might be applicable to the treatment of metabolic diseases".

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of obesity-related chronic inflammation, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Sitosterol prevents obesity-related chronic inflammation by Kurano M1, Hasegawa K2, Kunimi M2, Hara M3, Yatomi Y1, Teramoto T4, Tsukamoto K. (Europe PMC)

Omega -3 Fatty Acids Induce Weight Loss Naturally in Obese with Type 2 Diabetes

By Kyle J. Norton

Today, the prevalence of extremely overweight and obese children caused by an unhealthy diet and lifestyle change over 2 decades of economic prosperity, in the southeast Asian population has raised concerns of the scientific community,

Overweight and obesity have reached epidemic proportions in many countries, affecting even younger age populations inducing an economic burden in the health care system for treatment of obesity-related disorders such as diabetes, hypertension, and cardiovascular diseases(1).


Obesity is a chronic and medical condition caused by excess body fat accumulated to some extent that impacts personal health. The hallmark of obesity is attenuated metabolism and structural cell changes in the obese fat observed by reducing metabolic activity.

Visceral fat is a layer of fat that surrounds the organs. Overexpression of visceral fat has been found to promote insulin resistance, diabetes, heart disease, and inflammation.

In obese, accumulation of visceral fat is predominant in the intra-abdominal cavity.

According to the BMI index, a person is considered overweight, if he/she has a BMI between 25 to 29.9 kg/m2. A BMI of 30 kg/m2 or more is an indication of obese.

Weight loss is a process that intentionally reduces the total body mass, through the decrease of fluid, body fat or adipose tissue or lean mass.

Due to the widespread obesity in North America (over 68% of the US population is either overweight or obese), many weight loss products were created by manufacturers. 

The weight loss products is a 66 billion business in the US, according to the statistic provided by the Marketdata LLC research firm. And the business continues to grow at a rapid rate.

Is the weight loss products worked? I don't think so. Otherwise, the percentage of the overweight population in the US should be decreased substantially.

In other words, all weight loss products may have a complex structure or a long-term commitment before the results can be seen.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic diseases associated with obesity, researchers examined the relationship between levels of serum eicosapentaenoic acid (EPA), arachidonic acid (AA), as well as EPA/AA ratio and weight loss during hospitalization in participants considered to be overweight, with type 2 diabetes.

The study included 142 patients who were hospitalized for treatment of type 2 diabetes divided into two groups depending on the achievement in the reduction of body weight 3% or more during hospitalization.

According to the tested analysis,
* After adjustment was made for several confounders, the hazard ratio of effective weight loss for logarithmical serum EPA was 1.59 (95% CI 1.02-2.49, P = 0.04) and for logarithmical EPA/AA ratio 1.64 (1.03-2.61, P = 0.04), whereas the hazard ratio for effective weight loss for logarithmical serum AA was 1.11 (0.45-2.78, P = 0.82).

* Furthermore, after dividing EPA/AA ratio and serum EPA into quartiles based on participant number, the hazard ratio for the highest quartile of EPA/AA ratio was 2.33 for the highest quartile of serum EPA 1.60 (0.80-3.19, P = 0.18) compared with the lowest quartile.

More precisely, EPA is involved in body weight change under a caloric-restriction regimen.

In other words, a high serum level of EPA, relative to the level of AA, can lead to a reduction of adipose tissue weight through the anti-inflammatory effects of EPA.

Based on the finding, researchers said, " EPA/AA ratio was found to be a better predictor of medical intervention for weight loss among overweight patients with type 2 diabetes, compared with serum EPA level".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for inducing weight loss, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Eicosapentaenoic acid/arachidonic acid ratio and weight loss during hospitalization for glycemic control among overweight Japanese patients with type 2 diabetes: a retrospective observational study by Nakanishi S1, Hirukawa H2, Shimoda M2, Tatsumi F2, Kohara K2, Obata A2, Okauchi S2, Kinoshita T2, Sanada J2, Fushimi Y2, Nishioka M2, Kan Y2, Tomita A2, Mashiko A2, Horiya M2, Iwamoto Y2, Mune T2, Kaku K3, Kaneto H. (PubMed)
(2) Rising Burden of Obesity in Asia by Ambady Ramachandran and Chamukuttan Snehalatha(Journey of Obesity)

Lycopene Processes Anti Anti Platelet Aggression Activity

By Kyle J. Norton

Platelet aggregation is a condition of platelets clumping together in the blood. In most cases, the process is to protect the vascular injury against additional bleeding and microbial pathogenic invasion.

In other words, platelet aggregation is stimulated by the first-line immune response after sensing bodily injury or damage accompanied by the production of pro-inflammatory cytokines to defend
the injured area against infection.

Platelet disorders can lead to abnormal bleeding. Most common types of genetic proposition of platelet disorders including disorder of platelet adhesion, aggregation, secretion, and procoagulant activity.

If your blood platelet count falls below the normal range from 150,000 to 450,000 platelets per microliter of circulating blood, you are considered thrombocytopenia.

Believe it or not, platelet count that falls below 10,000 platelets per microliter are dangerous. Epidemiologically, severe thrombocytopenia can be fatal.

 Most common symptoms of platelet disorders are unexplained bruising throughout the body, bleeding from your nose, mouth, or gums, under your skin, muscles, and joints and heavy or prolonged menstrual bleeding,

In severe cases, patients may also experience symptoms of vomiting blood,  blood in your feces and internal bleeding.

Conventionally, most common medication with blood-thinning activity such as aspirin (ASA) and other drugs containing aspirin non-steroidal anti-inflammatory drugs and some antibiotics may have a strong implication of the formation of platelets coagulation.

Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and perform various functions in photosynthesis.

On finding a potent ingredient for the treatment of heart disease, scientists compared the antiplatelet effect of lycopene with aspirin.

In vitro, various concentrations of Aspirin (140 μmol/L) and lycopene (4, 6, 8, 10, and 12 μmol/L) were studied against adenosine-5'- diphosphate (ADP) (2.5 μM/L) and collagen.

Based on the tested analysis, all concentrations of lycopene (4-12 μmol/L) exhibited a reduction of maximum platelet aggregation induced by aggregating agents ADP and collagen comparable with aspirin.

Furthermore, lycopene at concentration 10 μmol/L showed a maximum platelet inhibition (47.05%) of ADP, whereas lycopene at concentration 8 μmol/L showed maximum platelet inhibition (54.26%) of collagen.

In other words, lycopene protects the cardio function selectively and dose-dependently.

However, all 4 μmol/L of lycopene combined with 140 μmol/L and 70 μmol/L aspirin showed greater inhibition of platelets compared to aspirin 140 μmol/L alone, against both ADP and collagen.

Based on the findings, researchers said, "The study favorably compares lycopene and aspirin with respect to their antiplatelet activities against ADP and collagen" and "Lycopene can be considered as a potential target for modifying the thrombotic and pro-inflammatory events associated with platelet activation".

Taken altogether, lycopene found in tomato may be considered an anti-platelet aggresion phytochemical, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You.  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: An in vitro study by Sawardekar SB1, Patel TC1, Uchil D. (PubMed)
(2) Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation by Hsiao G1, Wang Y, Tzu NH, Fong TH, Shen MY, Lin KH, Chou DS, Sheu JR. (PubMed)

Leeks, The Natural Anti High Blood Cholesterol Functional Food

By Kyle J. Norton

Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.

Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.

More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.

In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).

Low-density lipoprotein is needed for our body to build cell walls, make hormones and vitamin D, and create bile salts that help you digest fat. However, overexpression of LDL can induce plaque accumulated on the arterial wall, leading to atherosclerosis, a major cause of cardiovascular disease.

Low-density lipoprotein is produced by the liver or from the dietary sources. High-density lipoprotein neutralizes the levels LDL by returning them to the liver.

Some researchers suggested that diet high in trans fats, saturated fat, sugar, smoking, medical conditions such as diabetes or high blood pressure are associated with the increased risk of high blood cholesterol.

According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.

Although there are many risk factors such as obesity, large waist circumference, physically inactive, smoking and diabetes associated with the onset of high blood cholesterol, researchers suggested that a poor diet with rich in saturated and trans fat, processed foods is the major cause of high blood cholesterol in the Western world.

Epidemiological studies indicated a healthy diet that contains a high amount of fruits and vegetables and whole-grain have a positive on blood cholesterol. In other words, hyperlipidemia can be prevented by a healthy diet.

Leek is a genius of Allium, belonging to the vegetable family vegetable Alliacaea, the same as onion and garlic. Leeks are easy to grow from seed and usually reach maturity in the autumn months, and have few pest or disease problems.

On finding a potential plant that processes anti-high blood cholesterol, researchers examined the effects of oral administration of Persian leek on plasma and liver lipids.

The study included male Syrian hamsters that were randomly divided into three groups: control (standard diet), high-fat control (high-fat/high-cholesterol diet), Persian leek (high-fat/high-cholesterol diet + 1% per weight of diet from dried powdered Persian leek) for 14 weeks.

Before treatment of a high-fat diet showed an increase of plasma and liver lipids compared to a standard diet.

Administration of Persian leek to the high-fat/high-cholesterol diet resulted in no significant changes in the concentration of the plasma lipids or liver cholesterol.

Liver triglycerides (TG), plasma Alanine aminotransferase and gene expression of tumor necrosis factor- α associated with liver stress marker and pro-inflammatory cytokines, compared to high-fat diet only.

Collectively, researchers said, "Persian leek might be considered as a herbal food that can reduce liver TG accumulation induced by high-fat diets".

Taken altogether, leeks may be considered a functional food for the prevention and treatment of high blood cholesterol, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effects of Persian leek (Allium ampeloprasum) on hepatic lipids and the expression of proinflammatory gene in hamsters fed a high-fat/ high-cholesterol diet by Fatoorechi V1, Rismanchi M2, Nasrollahzadeh J. (PubMed)

Healthy Veggie Broccoli Inhibits Cardio-Risk Parameters in Diabetes

By Kyle J. Norton

Cardiovascular diseases (CVD) are a group of conditions associated with blood vessels and the heart.

According to the statistics provided by the World Health Organization, cardiovascular diseases are the number 1 cause of death globally. Approximately, 17.9 million people died from CVDs in 2016, representing 31% of all global deaths.

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Most common types of diabetes are
* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

As of today, there is no cure for type 1 diabetes. Treatment is focusing on managing blood sugar levels with insulin injection, diet, and lifestyle change.

* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.

The most common symptoms of type 2 diabetes are an increased thirst that won't stop with water intake, increased hunger (especially after eating), dry mouth, frequent urination, and unintentional weight loss.

* Latent autoimmune diabetes in adults (LADA), similar to type 1 diabetes, is a slow-progressing form of autoimmune diabetes. The disease is caused by the pancreas inability to produce enough insulin, because of slowly die-off of insulin-producing cells in the pancreas.

LADA is also known as type 1.5 diabetes because the disease has characteristics of both type 1 (autoimmune in nature) and type 2 diabetes.

Therefore, LADA shares the same risk factors and symptoms similar to those type 1 and 2 diabetes

* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.

Women with gestational diabetes are at an increased risk of type 2 diabetes in later life.

Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

On finding a potential plant that processes chronic diseases, researchers compared the effects of broccoli sprouts powder, as an alternative and complementary treatment, to those of standard triple therapy, as a common medical treatment in cardiovascular diseases (CVD) risk in patients with type 2 diabetes.

The study included 86 type 2 diabetic patients with positive H.pylori stool antigen test (HpSAg) who were randomized to receive one of the three following regimens:
* STT) Standard triple therapy (omeprazole 20 mg, clarithromycin 500 mg, amoxicillin 1000 mg, twice a day for 14 days),

* BSP) 6 g/d broccoli sprouts powder for 28 days, and

* Combination of these as STT + BSP. After 4 weeks of treatment.

Based on the results of the analysis of 77 participants who completed the study [STT (n = 28), BSP (n = 25), STT + BSP (n = 24)],

* Before treatment, the H.pylori eradication rates were 89.3%, 56.0% and 91.7% in STT, BSP and STT + BSP groups, respectively. 

* After the treatment, both systolic and diastolic blood pressure significantly decreased in STT + BSP group (P < 0.05).

* Serum triglycerides and TG/HDL-C ratio increased in STT patients group (<0.05).

* Serum hs-CRP levels significantly decreased in the patients who were treated with BSP per se (3.0 ± 2.5 at baseline vs. 2.3 ± 2.1 after the treatment, P < 0.05).

Collectively, researchers said, "Compared to standard triple therapy, BSP regimen in addition to considerable effects on H.pylori eradication had also favorable properties on cardiovascular risk factors following the H.pylori eradication".

Taken altogether, broccoli may be considered a functional food for reducing the risk of CVD in diabetes, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A comparative study of broccoli sprouts powder and standard triple therapy on cardiovascular risk factors following H.pylori eradication: a randomized clinical trial in patients with type 2 diabetes by Mirmiran P1, Bahadoran Z2, Golzarand M2, Zojaji H3, Azizi F. (PubMed)

Angelica Sinensis Improve the Body's Blood Circulation

By Kyle J. Norton

Blood is a body fluid that delivers necessary nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.

The heart formed part of the circulatory system is a muscular organ that pumps blood through the blood vessels to nourish the body tissues and organs.

The circulatory or cardiovascular system delivers nutrients and oxygen to all cells in the body, consisting of the heart and the blood vessels in the body.

More precisely, there are 2 types of large vessel
* The arteries carry blood away from the heart.

*The veins carry the blood back to the heart.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. High blood pressure means raising the pressure in your heart and staying high over time, damaging the body in many ways.

Most cases of heart dysfunction are associated with the reduced function of the heart muscle, leading to reduce blood flow that facilitates heart failure and the backup of blood into the lungs or rest of the body.

Heart disease is a condition in which the heart's inner lining of blood vessels is served damage that can impede the function of transportation of oxygen and nutrition of the heart to other cells and organs in the body.

Every day, more than 2,000 Americans die as a result of heart diseases. Approximately 60 million Americans have heart disease.

Believe it or not, 1 in 4 women in the US dies from heart diseases and coronary heart diseases.

Most common heart diseases associated with blood circulation are

* Heart diseases are affected by the arteries to the heart, such as coronary heart disease.

which is a condition of blockage of blood flow in the arteries, as a result of hardening arterial wall, cholesterol building up, chemicals, such as cadmium clog up arteries, etc. causes of narrowing coronary arteries.

* Heart diseases are affected by heart valves function in regulating blood flow such as valvular heart disease.

According to the statistics, heart disease is the leading cause of death in the US, approximately 610,000 people die of heart disease every year.

On finding a natural ingredient for the prevention and treatment of heart diseases, scientists examined the alcohol (Jiu Danggui, JDG) and charred DG are the main processed products of Angelica sinensis (Danggui, DG) on blood stasis syndrome (BSS).

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

According to the analysis of the results of hemorheology, coagulation function parameters and metabolomics,

* In BSS model, JD demonstrated the best in DGPPs intervention in significant relief rats' BSS.

* DGPP intervention showed different degrees of reverse effect on these metabolites associated with the expression of the syndrome in the tested model, and

* JDG was found to be the most effective owing to extensive regulation effect on differential metabolites.

Based on the results, researchers suggest, "This study provides a reference for understanding the pathological mechanism of BSS and the mechanism of DGPPs, which lays a theoretical foundation for the rational use of DGPPs in clinical practice".

Taken altogether, Dandelion may be considered a remedy for the treatment of blood stasis syndrome (BSS), pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Metabolomics study on promoting blood circulation and ameliorating blood stasis: Investigating the mechanism of Angelica sinensis and its processed products by Yuan Z1, Zhong L1, Hua Y1, Ji P1, Yao W1, Ma Q1, Zhang X1, Wen Y1, Yang L1, Wei Y. (PubMed)

Eyebright (Euphrasia), A Natural Antimicrobial Herbal Medicine

By Kyle J. Norton

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections.

Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.

Infectious diseases are a medical condition caused by pathogenic microorganisms, including bacteria, viruses, parasites or fungi.

Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.

In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.

According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.

More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.

Conventionally, most cases of infectious diseases except those caused by viruses are treated by antibiotics.

Microorganism, first observed by Anton van Leeuwenhoek in 1675 is a class of microscopic organisms, including a bacterium, virus, or fungus.

Believe or not, single-celled like bacteria, algae, and protozoa, or multicellular, such as algae and fungi can survive under all types of extreme environments.

And less than 1% of bacteria, can invade and cause infection and diseases.

Although the discovery of human antibiotics is medicines that kill or slow the growth of bacteria, however, overuses of the antibiotics have been found to induce microbial resistance to certain drugs.

On finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the antimicrobial effects on the essential oil extracted from Eyebright, Euphrasia rostkoviana Hayne (Scrophulariaceae).

Eyebright is one of the species of flowering plants, genus Euphrasia, belonging to the family Orobanchaceae, native to Europe. 

The plant has been used in traditional and herbal medicine to treat eye infection and to relieve inflammation caused by colds, coughs, sinus infections, sore throats, and hay fever.

According to the analysis of eye infections induced by Enterococcus faecalis, Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, S. epidermidis, Pseudomonas aeruginosa, and Candida albicans,
* 70 constituents isolated from the essential oil that inhibited infection, the n-hexadecanoic acid (18.47%) was the main constituent followed by thymol (7.97%), myristic acid (4.71%), linalool (4.65%), and anethole (4.09%).

* The essential oil showed antimicrobial effect against all organisms tested with the exception of P. aeruginosa.

* Most importantly, the best activity was observed against all Gram-positive bacteria tested with the minimum inhibitory concentrations of 512 µg/mL.

Based on the results, researchers suggest, "This is the first report on the chemical composition of E. rostkoviana essential oil and its antimicrobial activity".

Taken altogether, Eyebright (Euphrasia) may be considered a remedy for the treatment of microbial infection, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Composition and Antimicrobial Activity of Euphrasia rostkoviana Hayne Essential Oil by Novy P1, Davidova H1, Serrano-Rojero CS1, Rondevaldova J2, Pulkrabek J3, Kokoska L. (PubMed)