Herbal Enchinanea, A Promising Antioxidant and Anti-inflammatory Agent

By Kyle J. Norton

Infection is a condition caused by a harmful microbial invasion of the body tissues

Most cases of bacterial infection are treated with antibiotics. However, bacterias are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.

Out of trillions of strains of bacteria in the world, only a few cause diseases in humans. Believe it or not, our gut contains trillion microorganisms, most of them are bacteria.

The most common symptoms of bacterial infection are redness and heat, swelling, fever, pain at the site of infection.

In severe cases, the patient may also experience symptoms of swollen lymph glands.

Most cases of bacterial infection are treated successfully if the types of bacteria that cause the infection are identified.

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, intake dietary sources of antioxidants may be necessary.

Echinacea also is known as purple coneflowers, is a flowering plant of the genus Echinacea, belongings to the family Asteraceae, native to eastern and central North America. The herb has been used in traditional and herbal medicine to treat or prevent colds, flu, infections by stimulating the immune function, etc.

On finding a potential phytochemical for the treatment of chronic infectious diseases, researchers examined Echinacea extracts anti antioxidant activities.

According to the analysis of the three Echinacea extracts which were labeled as A, B, and C (A, roots of Echinacea purpurea L. Moench; B, roots, leaves, flowers, and seeds of Echinacea purpurea; C, aerial parts and roots of Echinacea purpurea and roots of Echinacea Angustifolia DC),

* Extract C showed higher density (0.97 g/mL), dry matter (0.23 g/mL), phenols (137.5 ± 2.3 mEAG/mL), flavonoids (0.62 ± 0.02 mEQ/mL), and caffeic acid (0.048 mg/L) compared to A and B.

* A, B presented 11 alkylamides, whereas C presented those 11 and three more.

* B decreased edema (40%) on day 2 similar to indomethacin. A and C showed hypoglycaemic activity similar to glibenclamide.

* The antiproliferative effect was only detected for C (IC50 270 μg/mL; 8171 μg/mL; 9338 μg/mL in HeLa, MCF-7, HCT-15, respectively).

In other words, the roots of Enchinanea showed the highest antioxidant profiles and capacity compared to the other parts of the plant.

After talking about other factors into account, researchers said, "The difference in the chemical and pharmacological properties among extracts highlights the need to consider strategies and policies for standardization of commercial herbal extracts in order to guarantee the safety and identity of this type of products".

Taken altogether, herbal echinacea may be considered adjunct therapies in the treatment of diseases associated with chronic inflammatory diseases, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Echinacea plants as antioxidant and antibacterial agents: From traditional medicine to biotechnological applications by Sharifi-Rad M1, Mnayer D2, Morais-Braga MFB3, Carneiro JNP3, Bezerra CF3, Coutinho HDM3, Salehi B4,5, Martorell M6, Del Mar Contreras M7, Soltani-Nejad A8, Uribe YAH9, Yousaf Z10, Iriti M11, Sharifi-Rad J. (PubMed)

Herbal Ashwagandha, the Potential Anti Neuro-Inflammatory Herbal Remedy

By Kyle J. Norton

The central system is the complex of nerve tissues including the brain and spinal cord with functions to respond to the integrating sensory information.

Inflammation is a natural response of the immune system in which the macrophages of the first defense stimulates the production of blood palette to cover the wound in case of injury and production of proinflammatory cytokines to the site of infection to fence off the foreign pathogens.

Inflammation also can be triggered by the immune mistakenly attacked the body tissues in cases of autoimmune disease.

Neuroinflammation is a process of the immune system that responds to harmful pathogens that induced oxidative stress to the brain.

A nerve cell is a brain cell specialized in transmitting nerve impulses.

Neuroinflammation is a medical condition characterized by the inflammation of the central nervous tissues, including the brain and spinal cord.

There many risk factors associated with the onset of neuroinflammation similar to other tissues inflammation, including infection, traumatic brain injury, toxic metabolites, or autoimmunity.

In other words, neuroinflammation is a complex response to brain injury involving the activation of inflammatory cytokines and chemokines, and generation of reactive oxygen and nitrogen species.

Overnutrition in the Western world may be one of the main culprits associated with the widespread neuroinflammation in the aging population.

The neuroinflammatory disease can be acute or chronic. Chronic neuroinflammation that leads to the activation of glial cells and the recruitment of inflammatory cytokines into the brain is found to associate with neurodegenerative diseases.

Most cases of the neuroinflammatory disease associated with the loss of neuronal structure and function.can be measured by the typical inflammatory markers, including CSF Aβ1-42, tau and p-tau181, and a panel of 37 neuroinflammatory markers in patients with Alzheimer's disease.

Aswagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-ageing herbal medicine.

In the urgency to discover a natural ingredient for the prevention of chronic inflammatory diseases, researchers examined the neuroprotective activity of Ashwagandha (Withania somnifera) against the inflammation associated with neurodegeneration and cognitive impairments induced by systemic LPS administration using in vivo rat model system.

The study included young adult Wistar strain male albino rats randomized into four groups: (i) Control, (ii) LPS alone, (iii) LPS + ASH-WEX, (iv) ASH-WEX alone.

According to the tested analysis, orally administered ASH-WEX not only significantly suppressed the cognitive and motor-coordination impairments in rats, but also regulated the expression of various proteins involved in synaptic plasticity and neuronal cell survival.

In LPS-mediated microglial activation induced damage to neurons via direct cell to cell contact or through secretion of inflammatory mediators, the application of ASH-WEX and FIV pretreatment restored neurite outgrowth and protect neurons from apoptotic cell death.

In other words, LPS-induced neuroinflammation activated in microglial conditioned medium-treated neuronal cultures and microglial-neuronal co-culture were significantly demolished by the application of ASH-WEX.

Collectively, researchers said, "ASH-WEX can be used as a promising natural therapeutic remedial for the prevention of neurodegeneration and cognitive impairments associated with peripheral inflammation and neuroinflammation".

Taken altogether, Ashwagandha may be considered supplements for the prevention and treatment of neuroinflammation, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Withania somnifera (L.) Dunal ameliorates neurodegeneration and cognitive impairments associated with systemic inflammation by Gupta M1, Kaur G. (PubMed)

Cranberry Balances the Population of Gut Microbiota

By Kyle J. Norton

Gut microbiota or gastrointestinal microbiota, the complex community of microorganisms in our digestive tracts plays a critical role in a variety of metabolic functions, including produced vitamins, synthesized all essential and nonessential amino acids, and carried out biotransformation of bile.

The gut microbiota also maintains the key processes of nutrition-enhancing the digestive functioning, lipid, and energy metabolism by inducing the production of short-chain fatty acids (SCFAs), phenolics, and other molecules, and pathogen resistance by promoting the immune function.

In a healthy individual, the levels of gut microbiota are balanced that allow the body to function in an optimal way.

Overexpression of certain harmful bacteria in the gut such as E. coli can utilize a complex arsenal of virulence factors to colonize and persist in the intestine, leading to gut microbiota imbalance that facilitates the early onset of gastrointestinal diseases.

Balanced gut microbiota protects the intestinal structures and functions by attaching to the gut wall against the entry of pathogenic, enteroinvasive bacteria into the epithelial cells.

In the immune perspective, gut microbiota protects the intestines by alerting the immune response against foreign invasion through specific receptors, leading to an immune system in inducing the proinflammatory cytokines.

However, the imbalance of digestive gut microbiota has been found to induce a number of diseases, syndromes, and functional aberrations, including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), and wider systemic manifestations of disease such as obesity, and type 2 diabetes.

Imbalanced gut microbiota is found in obese patients, compared to healthy weight individuals.

Alterations in gut microbiota composition have been found in patients with a low-grade inflammatory state, leading to an increased risk of several diseases, including type 2 diabetes mellitus and cardiovascular disease.

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the protection of the digestive functioning, researchers investigated the effects of cranberry extract (CE) in high fat/high sucrose (HFHS)-fed mice on the gut microbiota.

Selected C57BL/6J mice were fed either a chow or an HFHS diet. HFHS-fed mice were gavaged daily either with vehicle (water) or CE (200 mg/kg) for 8 weeks. 

According to the results from differentiation,

* CE treatment decreased liver weight and triglyceride accumulation in association with blunted hepatic oxidative stress and inflammation.

* More importantly, CE treatment lowered intestinal triglyceride content and alleviated intestinal inflammation and oxidative stress, similar to those in the liver.

* Interestingly, CE treatment markedly enhanced the ratio of gut microbiota by increasing the proportion of the mucin-degrading bacterium Akkermansia in the tested subjects.

Taken altogether, cranberry may be considered a remedy for balancing the ratio of the gut microbiota, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice by Anhê FF1, Roy D2, Pilon G1, Dudonné S2, Matamoros S2, Varin TV2, Garofalo C3, Moine Q3, Desjardins Y2, Levy E4, Marette A. (PubMed)

How to Make Homemade and Natural Hand Sanitizers against #Coronavirus, According to Doctors

By Kyle J. Norton

According to Dr. Nina A. Gold and Dr. Usha Avva at the Hackensack University Medical Center
Joseph M. Sanzari Children's Hospital

Data suggests that more than 1.4 million patients in developed and developing countries worldwide are affected at any time. There is ample evidence that hand antisepsis reduces the transmission of healthcare-associated pathogens and the incidence of HCAI... and More

The link below will give you all the information that you need to make effective natural Hand Sanitizers

https://www.ncbi.nlm.nih.gov/books/NBK513254/

Herbal Dandelion(Taraxacum officinale) Inhibits the Diseases Associated with Dengue Virus Serotype 2

By Kyle J. Norton

Infection is a condition that caused the invasion of stimuli and micro pathogens, including viral infection.

Similar to bacterial infection, both infections shared common characteristics by spreading through coughing and sneezing by and contact with infected people, especially through kissing and sex.

However, unlike bacteria, a virus replicates only inside the living cells of an organism. Viruses can infect all types of life forms, including humans and microorganisms, such as bacteria and archaea.

Anti-viral effects are the process that certain substances are used to cause the destruction of a virus.

In the acute phase of viral infection, depending on the types of viruses, the viruses after entering the body start to attack the specific host cells. The cold and flu virus will attack the cells in the respiratory system and the human immunodeficiency virus (HIV), which causes AIDS, will attack the white blood cells of the immune system,

The viral infection has been known to carry over some different stage, after successfully attaching to the host cell, the virus to release its mRNA into the host cell, leading to the recruit of the host cell's enzymes to accelerate the viral multiplying, then breaking free from the host cell to start the cycle all over again.

The white blood cells in the systematic immune response in the acute phase of infection stimulate the production of the proinflammatory cytokines to the site of infection with an aim to protect our body by killing off the invaders.

The battle between the immune white blood cell and viral invaders in most cases an in the flavor of the side of the immune system, the invaders are killed and the infection is healed.

However, if the immune system can not kill off the invaders with 3 - 8 weeks, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.

Dengue virus (DENV) belongs to the Flavivirus genus and is transmitted by Aedes aegypti and Ae. Albopictus mosquitoes, found in tropical and subtropical regions of the world. In severe cases, dengue virus serotype 2 has been found to induce symptoms of severe plasma leakage, severe hemorrhage and/or severe organ impairment.

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the prevention and treatment of infectious diseases, scientists examined the cytotoxic concentration and the inhibitory effect of extracts or fractions from Urtica dioica, Taraxacum officinale, Calea integrifolia and Caesalpinia pulcherrima on the dengue virus serotype 2 (DENV2 replication on the BHK-21 cell line.
According to the tested differentiation,
* The methanolic extracts at 60 °C of T. officinale and U. dioica showed the higher inhibitory effects on DENV2 replication.

* The chemical analysis suggested that the higher activity fraction is found for U. dioica and T. officinale, at the IC50 values of 165.7 ± 3.85 and 126.1 ± 2.80 μg/ml, respectively.

The compounds which  exhibited the efficacy of T. officinale were luteolin and caffeoylquinic acid derivatives and quercetin diclycosides compared to the compounds in the active fraction chlorogenic acid, quercetin derivatives and flavonol glycosides (quercetin and kaempferol) in the U. dioica.

Based on the results, researchers suggest, "Two fractions from U. dioica and T. officinale methanolic extracts with anti-dengue activity were found. The compounds present in both fractions were identified, several recognized molecules have demonstrated activity against other viral species".

Taken altogether, dandelion may be considered an antioxidant remedy for the treatment of dengue virus serotype 2, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Taraxacum officinale and Urtica dioica extracts inhibit dengue virus serotype 2 replication in vitro by María R. Flores-Ocelotl,1,2,3 Nora H. Rosas-Murrieta,4 Diego A. Moreno,5 Verónica Vallejo-Ruiz,1 Julio Reyes-Leyva,1 Fabiola Domínguez,2 and Gerardo Santos-López. (PMC)

Herbal Coltsfoot(Tussilago farfara) Processes Antitussive Activity Against Coughing

By Kyle J. Norton

Coughing is a natural reflex that clears the throat of mucus or foreign pathogens. Frequent coughing may be a condition of infection caused by inflammation of the airway.

An acute cough is a condition that lasts for less than three weeks. Chronic coughing that lasts more than 3 weeks may be a condition of respiratory diseases, including asthma, allergies, gastroesophageal reflux disease (GERD), or bronchitis.

Phlegm produced in the lungs and lower respiratory tract is a type of mucus found mostly in acutely sick or longstanding health conditions patients.

Chronic mucus collected in the lungs has been associated with patients with tuberculosis (TB), pneumonia, a fungal infection, whooping cough early in life and measles.

Seriously, chronic mucus collected in the lungs increases a significant risk of further infections and more damage.

Antitussive is a type of substance used to prevent or relieve a cough.

The most common type of antitussive drugs used for the treatment of cough is dextromethorphan

Another expectorant available in OTC products is guaifenesin.

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.

On finding a potential compound for the treatment of chronic cough, researchers examined the anti-antitussive effect of Tussilagone (TSL) chemical constituents, chlorogenic acid (1), 3,5-dicaffeoylquinic acid (2), 3,4-dicaffeoylquinic acid (3), and 4,5-dicaffeoylquinic acid (4).isolated from the flower of buds of Tussilago farfara (Compositae).

The study included selected mice orally treated with these compounds and their mixture (in a ratio of 5:28:41:26 as in EtE) at doses of 10 and 20 mg/kg once daily for 3 days.

According to the tested analysis, chemical compounds 4,5-dicaffeoylquinic acid (4) exerted a significant anti-inflammatory activity by 49.7%.observed by the leukocyte count in the bronchoalveolar lavage fluid associated with acute airway inflammation compared to the other compounds.

Moreover, 4,5-dicaffeoylquinic acid (4) also inhibited 58.0% in cough frequency.

Based on the findings, researchers said, "The caffeoylquinic acids and their mixture, exhibiting significant antitussive,...and anti-inflammatory effects, could be considered as the main effective ingredients of FTF, and they may act in a collective and synergistic way.".

Taken altogether, coltsfoot may be considered an antitussive remedy, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antitussive, expectorant, and anti-inflammatory activities of four caffeoylquinic acids isolated from Tussilago farfara by Wu QZ1, Zhao DX1, Xiang J1, Zhang M1, Zhang CF1, Xu XH. (PubMed)

Angelica Sinensis Protects the liver Against Toxicity

By Kyle J. Norton

The liver is the largest internal organ in the human body and the only organ which can regenerate itself. The liver is the first line of the bodily toxin defense by filtering the blood that comes from the digestive tract, before passing it to the rest of the body.

The liver also produces cholesterol that plays a critical role in building strong cell membranes, producing steroid hormones and vitamin D and aiding the digestive function in food absorption and detoxifying chemicals and metabolizing drugs.

The hepatoprotective or liver protective effect is an action that maintains the liver's healthy functioning against any harmful toxins, including detoxification which is a natural process of our body to maintain the proper function and protect our organs and tissues against toxicity by eliminating toxins accumulated.

When they fail, the toxic accumulations cause a disruption of hormone production, damage the body's detoxification organs and weaken the immune system, leading to hormone imbalance and much chronic illness consequently.

Symptoms of liver diseases include jaundice, abdominal pain, and swelling, swelling in the legs and ankles, itchy skin, dark urine, and pale stool color, and a tendency to bruise easily.

There are no exact causes of liver disease. viruses, toxins, genetics, alcohol, and unknown causes are some prevalent factors found in patients with chronic liver disease, including cancer.

In the US, most cases of liver disease are a result of hepatitis viral infection and autoimmune diseases. Infectious viral hepatitis can produce toxins to protect them against the antioxidant enzymes produced by the host body and prevent the attack of the systematic immune response.

Furthermore, in recent years, excessive alcohol drinking has been found to induce alcoholic liver disease in many parts of Asia and America.

On finding a natural ingredient for the prevention and treatment of liver diseases, scientists examined the hepatoprotective effects of polysaccharides-enriched fraction from the root of Angelica sinensis in rodents.

Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

According to tested analysis,
* Intra-gastric administration of Angelica sinensis polysaccharides-enriched fraction (AP) at the doses of 50 or 75 mg/kg dose-dependently prevented liver toxicity induced by acetaminophen in mice but did not affect the serum acetaminophen concentration.
* AP inhibited the liver stress markers alanine transferase (ALT), malondialdehyde (MDA) and hepatic nitric oxide synthase (NOS) activities and glutathione level in the liver.

* In the carbon tetrachloride (CCl4) induced liver damage animals, AP showed weak protective activity.

* However, a higher dose of AP inhibited the MDA level without affecting the serum ALT level, the hepatic glutathione level instead while the NOS activity in CCl4 induced liver damage rats.

Based on the results, researchers suggest, "These findings suggest that the pathogenic mechanisms of both acetaminophen and CCl4 are different. AP is more effective in the protection against liver damage induced by acetaminophen, which is associated with the glutathione depletion and nitric oxide synthase activation in the liver".

Taken altogether, Dandelion may be considered a remedy for the protection against liver damage, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective effect of polysaccharides-enriched fraction from Angelica sinensis on hepatic injury by Ye YN1, Liu ES, Li Y, So HL, Cho CC, Sheng HP, Lee SS, Cho CH. (PubMed)
(2) Protection of Angelica sinensis (Oliv) Diels against hepatotoxicity induced by Dioscorea bulbifera L. and its mechanism by Niu C1, Wang J, Ji L, Wang Z. (PubMed)