Monday, 6 January 2020

Herbal Angelica Inhibits the Acute Coronary Syndrome in Patient with Renal Deficiency

By Kyle J. Norton

The acute coronary syndrome is a medical emergency associated with a range of conditions caused by sudden, reduced blood flow to the heart, leading to heart muscle damage and brain apoptosis depending on the affected location.

The acute coronary syndrome is associated with the severity of buildup of plaque deposits in and on the walls of the coronary arteries.

Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood.

Arteries formed a part of blood vessels and circulatory system with function to deliver oxygen and nutrients to heart muscles.

Depending on the severity of the blockage, a complete blockage is life-threatening. Symptoms of acute coronary syndrome, chest pain or discomfort, pain or discomfort in one or both arms, the jaw, neck, back or stomach, shortness of breath, dizziness, and nausea.

If the chest pain is persistent with no sign of stopping, please call 911 immediately.

The most common treatment of acute coronary syndrome is medicine to reopen the artery. However, in severe cases, angioplasty (a inflate a small balloon) may be necessary.

Traditionally, over many decades, patients with acute coronary syndrome are likely to be treated by oxygen therapy.

Dr. Pankaj Garg in the examing the effects of oxygen therapy on patients with acute coronary syndrome wrote, " However, more recently, there have been many reports of harmful effects of high-flow oxygen in ACS patients where the patient might not be hypoxic".

Anf "High flow oxygen has been shown previously to reduce cardiac output,2 attributes to arterial vasoconstriction35 and also to increase systemic vascular resistance.6 More recently, two systematic reviews suggest that the routine use of high-flow oxygen in uncomplicated myocardial infarction may result in greater infarct size and possibly increase the risk of mortality".

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China. The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a potential compound that inhibits acute coronary syndrome, researchers examined the neuroprotective effects of Chinese herbal medicines in the cardiovascular outcome among patients with acute coronary syndrome (ACS) and renal insufficiency after the percutaneous coronary intervention (PCI).

The study included population consisted of 215 subjects in the control group who were treated with western medicine standard therapy, and 211 subjects in the treatment group who were treated with Chinese herbal medicines (Fufang Chuanxiong Capsule and Xinyue Capsule) for 6 months.

Participants are from the 5C trial with post-PCI patients suffered from ACS with mild-to-moderate renal insufficiency (30 mL•min-1•1.73 m-2 < estimated glomerular filtration rate≤89 mL•min-1•1.73 m-2).

According to the endpoints including the composite of cardiac death, nonfatal recurrent myocardial infarction, and ischemia-driven revascularization assays, after one year of following up of 2 groups
*There were 16 cases of the primary endpoint in the control group and 6 cases of the primary endpoint in the treatment group with an absolute risk reduction ARR=0.046. elative risk RR= 0.38.

* There were 15 cases of secondary endpoint in the control group and 5 cases of secondary endpoint in the treatment with ARR= 0.041 and RR=0.34

In other words, the treatment of Chinese and Western medicines showed a strong effect in reducing the risk of the acute coronary syndrome in patients with renal deficiency.

However, The eGFR levels associated with the renal functioning in the treatment group were significantly higher, compared to the higher levels in the control group.

Based on the findings, researchers said, "Chinese herbal medicines plus western medicine standard therapy improved clinical outcomes in patients with ACS and mild-to-moderate renal insufficiency. Additionally, this study also demonstrated Chinese herbal medicines were useful in deferring the decline of renal function".

Taken altogether, herbal Angelica in combination with other herbal medicines that may be considered a remedy for the treatment of acute coronary syndrome, pending to larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The efficacy of Chinese herbal medicines on acute coronary syndrome with renal insufficiency after percutaneous coronary intervention by Zhang DW1, Wang SL2, Wang PL1, Du JP1, Gao ZY1, Wang CL1, Xu H1, Shi DZ. (PubMed)
(2) Oxygen therapy in acute coronary syndrome: current NICE recommendations by Pankaj Garg. (PMC)

Dandelion (Taraxacum officinale) Reduces the Side Effect of Chemo Drug Induce-Anorexia

By Kyle J. Norton

Eating Disorders are a group of abnormal eating habits associated with a person's preoccupation weight, involving either insufficient or excessive food intake.

Eating disorders can be classified into
* Anorexia nervosa is a type of eating disorder usually develop in the teen years and affects over 90% of females, because of excessive food restriction and irrational fear to become fat due to the wrongly influenced media as attractiveness is equated to thinness.

* Bulimia nervosa
Bulimia nervosa is a medical condition of consuming a large amount of food in a short amount of time or one setting (binge eating), followed by self-induced vomiting, and taking a laxative or diuretic and/or excessive exercise, etc. to compensate for the binge. Bulimia Nervosa also affects almost 90% of females.

* Binge eating disorder
Binge eating disorder is a medical condition of compulsive eating of huge amounts of food while feeling out of control and powerless to stop. It is a common eating disorder in the United States affecting 3.5% of females and 2% of males.

Most common symptoms of Anorexia nervosa are
* Weight loss, sometimes severe as a result of malnutrition.

* Refusal to maintain a normal or minimally above normal body mass index for their age and Dieting despite being thin or dangerously underweight

* Intense fear of gaining weight and primary or secondary amenorrhea

In the study Eating disorders. A review and update by Haller E. at the University of California indicated Anorexia nervosa is diagnosed when a person refuses to maintain his or her body weight over a minimally normal weight for age and height, such as 15% below that expected, has an intense fear of gaining weight, has a disturbed body image, and, in women, has primary or secondary amenorrhea(2).

* Obsession with calories and fat content of food and try to avoid eating altogether. They deny hunger and will usually avoid eating around others as well as avoiding situations where food might be present(3).

* Disturbance to body image the person hold of him/herself
In the study of Eating disorders. A review and update, Dr. E Haller indicated that anorexia Nervosa is diagnosed when a person refuses to maintain his or her body weight over a minimally normal weight for age and height, such as 15% below that expected, has an intense fear of gaining weight, has a disturbed body image, and, in women, has primary or secondary amenorrhea(4).

*Abdominal pain and distention
Anorexia nervosa is also associated with abdominal and with a sensation of elevated abdominal pressure.


Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the treatment of eating disorders in chemotherapy patients, scientists examined the anti-anorexia of herbal mixtures extracts LCBP‑Anocure‑16001‑3 (LA16001, LA16002, LA16003), composed of Atractylodes japonica, Angelica Gigas, Astragalus membranaceus, Lonicera japonica Thunb., Taraxacum Platycerium H. Dahlstedt and Prunella vulgaris var. Asiatica (Nakai) Hara.

In a cisplatin‑induced anorexia mouse model, treatment with LA16001 prevents body weight loss. However, all three extracts were demonstrated to improve food intake.

LA16001showed to altered expression levels of ghrelin, leptin, and interleukin‑6 associated with infection.

In other words, LA16001 modulated the interleukin‑6 activation of phosphring the caorylation of Janus kinase 1 and signal transducer and activator of transcription 3 during the course of infection induce-inflammation observed by the increase of the number of white blood cells and neutrophils. 

Based on the findings, researchers said, " the herbal formula LA16001 may be able to prevent chemotherapy‑induced anorexia and may have potential as a novel therapeutic strategy for the adjuvant treatment of patients with cancer".

Taken altogether, dandelion may be used to enhance and prevent side effect in a combination with chemo drugs in chemotherapy, pending to the confirmation of the larger sample size and multicenter human study. 



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia by Woo SM1, Lee KM2, Lee GR2, Park JY2, Lee HJ2, Bahn HJ2, Yoon HS2, Kim JY2, Shin YC3, Cho SG4, Ko SG. (PubMed)
(2) Eating Disorders: Anorexia nervosa - Symptoms and Signs by Kyle J. Norton


Herbal Turmeric Accelerates Wound Healing

By Kyle J. Norton

Wound healing is the process to repair the wound after injury or damage through many stages, including the acute phase of infection.

First, the immune system after sensing the skin wound activates the immune first-line defense stimulates the constriction of the blood vessel to reduce blood flow, activate platelets, and many different clotting factors to cover the wound area.

Then, the white blood cells also up-regulate the proteins associated with the production of proinflammatory cytokines to the site of infection to kill off all the invasive organisms.

In most cases, due to overproduction of proinflammatory cytokines, patients may experience symptoms of fever, and localized pain, redness, and swelling.

Furthermore, the production of pro-inflammatory cytokines in some case can cause the death of nearby healthy cells, leading to the formation of irreversible scars, as seen in the liver.

After the inflammatory phase, the new blood vessels are formed and the new granulation tissues are built.

The final phase of the wound healing is involved in the remodeling of collagen from type III to type I cellular activity reduces.


If the process of skin healing is interrupted, it may lead to abnormal cell membrane repair, a major cause of skin scars.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

In the urgency to discover a natural ingredient for the accelerated wound healing researchers examined the curcumin effects on wound healing properties.

Based on the tested analysis curcumin administration showed a significant effect on various stages of the natural wound healing process to hasten to heal.

Epidemiological studies suggested curcumin reduces the body's natural response to cutaneous wounds by inhibiting the inflammatory and oxidative expression caused by injury and wound.


Furthermore, curcumin also enhanced granulation tissue formation, collagen deposition, tissue remodeling, and wound contraction.

Moreover, curcumin may be used as a topical application to alter the maximum therapeutical effects on skin wounds.

Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements for the accelerated healing, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin as a wound healing agent by Akbik D1, Ghadiri M1, Chrzanowski W2, Rohanizadeh R. (PubMed)

Sunday, 5 January 2020

Herbal Cramp Bark (Vib urnum opulus), the Anti-Endometriosis Functional Herb

By Kyle J. Norton

Endometriosis is a painful disorder characterized by endometrial cells that grow in other areas in the reproductive organs, such as ovaries, fallopian tubes,..... and the tissue lining your pelvis, outside of the uterus.

Most cases of endometriosis are in the organs in the pelvic area, including ovaries and fallopian tubes.
Endometriosis also reacts to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through the menstrual period.

According to the statistics provided by the Clinical Center of Niš,
* About 20% of reproductive-age women with endometriosis are asymptomatic

* About 55% of women have developed the new onset of severe menstrual cramps

* About 25% of women with sub-fertility (less fertile than a normal couple), depending on the stages of endometriosis.

Endometriosis can be classified into 4 stages
* Minimal stage
The top surface, few in number. Commonly they are found in the inside wall of uterus, ligaments, and ovary, causing a significant reduction in both progesterone and its ratio with 17 beta-oestradiol, luteal dysfunction and abnormal secretory patterns(3). Minimal stage endometriosis may lead to unexplained causes of infertility(2).

* Mild stage
Deeper implants, greater numbers are presented. Commonly found in the same area as a minimal stage, causing worsening of oocyte quality. The mild stage of endometriosis may lead to infertility(4).

* Moderate stage:
Many implants, endometrial cysts are presented, affecting ovary function, and causing scar tissues and adhesion.

* Severe stage:
Intensive peritoneal implants, large endometriomas are presented with dense adhesion.

Conventionally, most cases of endometriosis are treated by pain medicines such as NSAIDs (non-steroidal anti-inflammatory drugs) and hormone therapy such as birth control pills with an aim to reduce pain and improve quality of life, including daily activity.

Cramp Bark is an ornamental plant, genus Viburnum, belonging to the family Adoxaceae, native to Europe and Asia. It has been used in traditional and herbal medicine as anti-spasmodic, anti-inflammatory, nervine. hypotensive agent and to treat menstrual cramps and pain, afterbirth, postpartum pains, excessive blood loss in periods, bleeding associated with the menopause, etc.

On finding a potential herbal medicine for the treatment of menstrual disorders, researchers examined
the effects of cramp-bark on endometriosis in an animal model.

In the endometriosis induced by suturing 15mm piece of the endometrium into the abdominal wall of Sprague Dawley rats, air-dried, powdered fruits of V. Opulus extracts sequentially with n-hexane, ethyl acetate (EtOAc), and methanol (MeOH) showed a strong effect in reducing the endometriotic volumes.

In other words, the EtOAc and MeOH extract-administered group showed a decreased of endometrial volumes to 30.1mm3 and 34.7mm3, compared to the control group, respectively.

Furthermore, EtOAc groups showed no endometrial adhesion.

Moreover, according to the histopathological data both EtOAc and MeOH extract-administered groups displayed significant remission in the levels of pro-inflammatory cytokines, compared to control.

The chemical compound associated with the anti endometriosis activity was found to be chlorogenic acid, according to HPLC analysis.

Based on the results, researchers said, "the effectiveness of the fruit extract of V. Opulus could be partially attributed chlorogenic acid. Other phenolic compounds could potentiate the activity due to their amount".

Cramp Bark(Viburnum opulus) may be considered an anti endometriosis remedy, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Viburnum opulus L.: A remedy for the treatment of endometriosis demonstrated by rat model of surgically-induced endometriosis by Saltan G1, Süntar I2, Ozbilgin S1, Ilhan M2, Demirel MA3, Oz BE1, Keleş H4, Akkol EK. (PubMed)

Herbal Angelica, the Antioxidant Herbal Remedy

By Kyle J. Norton

Antioxidants are stable atoms produced either by the host body or intake of dietary antioxidants rich food with the function that inhibits oxidation caused by free radicals.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer by inducing the alternation of lipids, proteins, and cell DNA damage.

Colon cancer is relatively very common and slowly growing and progressing in a predictable way.

Most cases of primary colon cancer start in the cell on the surface of the inner lining of the colon. At the early stage. most patients with colon cancer do not experience any symptoms.

However, at the advanced stage, the tumor not only can spread to other healthy tissue and organs a distance away through blood and fluid circulation but also suppress the nearby tissue and nerve cells.

The progression of colon cancer at this stage not only induces symptoms of the change in bowel habits, the change in the consistency of your stool, that lasts longer than four weeks but also causes rectal bleeding and persistent abdominal severe pain.

According to the statistic by the American Cancer Society, in the US, there are
97,220 new cases of colon cancer diagnosed in 2018. The lifetime risk of developing colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a potential compound for the prevention and treatment of diseases associated with oxidative stress, researchers examined the antioxidant activity of Angelica dahurica extract in the HT-29 colon cancer cell line.

According to the A HPLC-DAD analysis, the antioxidant anti-cancer activity of the extract was attributed to the phytochemicals Imperatorin and isoimperatorin, the major coumarins in the ethanol-ethyl acetate active fraction.

In other words, Angelica dahurica extract exerted the antioxidant cancer effect by activating the pro-apoptotic proteins caspase cascade and cell cycle arrest and inhibiting the proteins associated with anti-apoptotic expressions

Based on the results, researchers said, "the ant-cancer activity of the organic extract of Angelica dahurica Radix against colon cancer cells".

Taken altogether, Herbal Angelica consists of the ethanol-ethyl acetate active fraction maybe considered a functional herbal medicine for improving antioxidant activity against colon cancer,  pending to larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-oxidant and anti-cancer activities of Angelica dahurica extract via induction of apoptosis in colon cancer cells by Zheng YM1, Shen JZ2, Wang Y2, Lu AX2, Ho WS. (PubMed)
Antimigraine
(1) Chemical Composition and Antimigraine Activity of Essential Oil of Angelicae dahuricae Radix. by Sun J1, Li H2, Sun J2, Liu H3, Chen J2, Wang C. (PubMed)

Turmeric Protects Chemo Patients Against the Hand-Foot Syndrome

By Kyle J. Norton

Hand-foot syndrome also known as palmar-plantar erythrodysesthesia is side effects in some patients undergoing cancer treatments.

Redness, swelling, and pain on the palms of the hands and/or the soles of the feet are some of the most common symptoms of hand-foot syndrome patients.

In severe cases, patients may also experience symptoms of cracked, flaking, or peeling skin, blisters, ulcers, or sores on the skin and difficulty walking or using your hands.

The leading cause of chemotherapy-induced hand and foot syndrome was attributed to damage the growth of skin cells or small blood vessels in the hands and feet once the drug including Capecitabine (Xeloda) Cytarabine (Cytosar-U) Docetaxel (Docefrez, Taxotere) Doxorubicin (Adriamycin) is circulating in the bloodstream.

Most cases of hand and foot syndromes occur in the first 6 weeks of chemo-target drug treatment. In some cases, the syndrome can occur in the 2nd to 3rd months after chemotherapy.

Conventionally, treatment of hand and foot syndrome by identifying the chemo drug that causes of the condition and focusing to reduce inflammation with the use of anti-inflammatory medication such as corticosteroids.

The experts in the chemo care suggested reducing friction and heat exposure to your hands and feet such as hot water, short showers, avoid increased pressure, on the soles of the feet or palms of hands, reducing exercise that affects the food and hand.and avoid any activity that causes excessive pressure and friction on the palms may reduce the severity of hand and foot syndrome.

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia.


The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On findings, a potential compound for the treatment of complications in the first cycle of treatment in approximately 40% to 50% of patients who received capecitabine, researchers examined the efficacy of curcumin on hand-foot syndrome (HFS).

The study included 40 patients whose mean age was 62 years inclduing female (80%) with 52% had breast cancer, and 47.5% had GI tumors.

According to the analysis before and after treament of turmeric at a dose of 4 g/day (2 pills 12 hours apart) starting at the beginning of capecitabine treatment and lasting six weeks of the enrolled patients, 11 of 40 patients with capecitabine developed HFS whereas four patients developed HFS equal or superior to grade 2.

The inflammatory markers such as interleukin-6 (IL-6) showed no correlations in patients with HFS.

Co admiration of turmeric and capecitabine displays a lower rate of HFS, especially in grade 2 or higher.patients.

Taken altogether, turmeric may be considered supplements and adjunct therapy combined with conventional medicine for the prevention of hand and foot syndrome induced by capecitabine, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcuma longa (Turmeric) for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Pilot Study by Scontre VA1, Martins JC2, de Melo Sette CV2, Mutti H2, Cubero D2, Fonseca F2, Del Giglio A. (PubMed)
(2) What Is Hand-Foot Syndrome? by Chemocare

Saturday, 4 January 2020

Red Cabbage, the Potential Anti-Mammalian Cancer Healthy Food

By Kyle J. Norton

Cancers are a class of chronic diseases associated with cell growth in the tissue and organs. At the advanced stage, malignant cells can travel a distance away from the original site to infect other healthy cells and tissues.

There are many types of cancer, depending on the location where cancer begins.

As of today, researchers do not know what are the exact cause of cancers. however many researchers believe, exposure to environmental toxins, genetic mutation, and an unhealthy diet and lifestyle are the most common risk factors associated with the onset of the diseases.

Genetic mutation od BRCA1 and BRCA2 are associated with hereditary breast and ovarian cancer and alternation of gene PTEN.that suppress the growth of tumors also increase the risk of cancers.

According to the statistic provided by the UK Cancers research, in 2012, an estimated 14.1 million new cases of cancer occurred worldwide.

Sadly, more than 4 in ten cancers occurring worldwide are in countries at a low or medium level of the Human Development Index (HDI).

The four most common types of human cancer, occurring worldwide are 
* Lung Cancer
Lung cancer is a medical condition characterized by irregular cell growth in the tissues of the lung. At the later stage, the cancerous cell may invade other healthy tissues and organs a distance away from the original site.

According to statistics, In 2015, approximately 26,600 Canadians will be diagnosed with lung cancer and 20,900 will die of it.

* Female breast cancer
Breast cancer is a medical condition characterized by cell growth irregularly and disorderly in the breast tissue.

Most cases of breast cancer start in the cell on the surface of the inner lining of the breast tissue before spreading into deeper layers of the breast.

* Colorectal cancer
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of cells DNA.

Colorectal cancer is relatively very common and slowly growing and progressing cancer.

The disease is also the third most commonly diagnosed cancer in developed countries, including the US and Canada.

* Prostate cancer
Prostate cancer is defined as a condition in which the cells of the prostate have become cancerous, causing abnormal cell growth which spread to the distant parts of the body. Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.

Primary prostate cancer normally starts from the cell on the surface of the inner lining of the prostate tissue and gradually spreads to the deeper part of the prostate.

Kale is a species of Brassica Oleracea, belongings to the family Brassicaceae, native to coastal southern and western Europe. The veggie leave is highly nutritious cultivated as foods in most parts of Europe.

On finding a potent compound for the prevention and treatment of cancers, researchers examined, in vitro cytotoxic effects and the mode of interaction of biologically synthesized Ag and Au nanoparticles (NPs) using Brassica oleracea L. var. capitata f. Rubra (BOL) against HT-1080 cancer cells and bacterial cells.

According to the tested analysis,
* The Ag NPs showed a stronger free radical scavenging activity in vitro compared to the Au NPs.

* Both nanoparticles (NPs) exerted the cytotoxic effects are mediated through nuclear morphological changes and DNA damage.

* Intracellular localization of Ag and Au NPs induced HT-1080 cancer cells apoptosis.

These results strongly suggested that the Ag and Au NPs have easily entered and accumulated into the cytosol and nucleus to activate the inflammatory and apoptosis pathways to induce damage in cancer cell DNA. 

Most importantly, Ag and Au NPs showed no clear toxic effects and no nuclear abnormalities in peripheral blood cells

Taken altogether, red cabbage may be considered a functional food for the treatment of mammalian cancer, pending to the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Interaction of silver and gold nanoparticles in mammalian cancer: as real topical bullet for wound healing- A comparative study by Sivakumar AS1, Krishnaraj C2, Sheet S3, Rampa DR4, Kang DR1, Belal SA1, Kumar A5, Hwang IH6, Yun SI2, Lee YS3, Shim KS. (PubMed)