Phytochemical β-Carotene Reduces the Risk of ER Breast Cancer

By Kyle J. Norton

The women's breasts are made up of specialized tissue that produces milk (glandular tissue) and fatty tissue. The size of a women's breast is totally determined by the amount of fat.

Cancer is a group of chronic and medical diseases associated with the growth of the irregular cells caused by DNA alternation.

Breast cancer is a medical condition characterized by cell growth irregularly and disorderly in the breast tissue.

Most cases of breast cancer start in the cell on the surface of the inner lining of the breast tissue before spreading into deeper layers of the breast.

In the early stage, most patients with breast cancer may experience lumps on the breast or surrounding the breast.

However, breast skin irritation or dimpling, nipple pain, nipple retraction (turning inward), redness and scaliness that cannot be healed within 3 weeks are also the signs and symptoms of breast cancer.

At the later stage, after colonizing most parts of the breast, the breast cancer cells may travel a distance far the way to infect other healthy cells and tissue.

The causes of breast cancer are unknown, As of today, researchers cannot explain why people with the same health conditions in the same family, some are susceptible to the onset of breast cancer while others do not.

In Canada, according to the statistic, 11% of women will develop breast cancer by the time they reach 90 years of age.

Just about 20% of breast cancers in Canada are diagnosed in women under 50, while almost 30% are diagnosed in women over 70 years of age.

Believe it or not, In 2018, approximately 266,120 new cases of invasive breast cancer were diagnosed in women in the U.S.

The 5 years survival rate of breast cancer diagnosis at the early stage is 100%. Therefore, women at a higher risk of breast cancer should examine their breasts at least once a month for preventive measures.

β-Carotene is a phytochemical in the class of Carotenes, belongings to the group of Carotenoids (tetraterpenoids), found abundantly in dark, leafy greens and red, orange and yellow fruits and vegetable.
On finding a potential phytochemical for the prevention and treatment of cancer, researchers evaluated the associations of plasma carotenoid, retinol, tocopherol, and vitamin C concentrations and risk of breast cancer.

In a nested case-control study within the European Prospective Investigation into Cancer and Nutrition cohort, 1502 female incident breast cancer cases were included, with an oversampling of premenopausal (n = 582) and estrogen receptor-negative (ER-) cases (n = 462). Controls (n = 1502).

According to the tested analysis, α-carotene and β-carotene were inversely associated with risk of ER- breast cancer with the relative odds ration of 0.61 and 0.41 respectively, compared to no statistically in other analytes associated with ER- breast cancer.

Furthermore,  β-carotene was a statistically significant difference between ER- and ER+ tumors.

In other words, α-carotene showed no statistical effects on ER+ breast cancer.

However, there was no statistically significant interaction between smoking, alcohol, or BMI and all investigated plasma analytes.

Based on the findings, researchers said, " higher concentrations of plasma β-carotene and α-carotene are associated with lower breast cancer risk of ER- tumors".

Taken altogether, β-Carotene may be considered a functional food for the prevention and treatment of ER breast cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of β-Carotene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Plasma carotenoids, vitamin C, tocopherols, and retinol and the risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition cohort by Bakker MF1, Peeters PH2, Klaasen VM3, Bueno-de-Mesquita HB4, Jansen EH5, Ros MM5, Travier N6, Olsen A7, Tjønneland A7, Overvad K8, Rinaldi S9, Romieu I9, Brennan P9, Boutron-Ruault MC10, Perquier F10, Cadeau C10, Boeing H11, Aleksandrova K11, Kaaks R12, Kühn T12, Trichopoulou A13, Lagiou P14, Trichopoulos D15, Vineis P16, Krogh V17, Panico S18, Masala G19, Tumino R20, Weiderpass E21, Skeie G22, Lund E22, Quirós JR23, Ardanaz E24, Navarro C25, Amiano P26, Sánchez MJ27, Buckland G6, Ericson U28, Sonestedt E28, Johansson M29, Sund M30, Travis RC31, Key TJ31, Khaw KT32, Wareham N33, Riboli E34, van Gils CH. (PubMed)

Healthy Food Cruciferous Vegetables in Reducing the Risk of Type 2 Diabetes

By Kyle J. Norton

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

In other words, diabetes occurs when cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Most common types of diabetes are

* Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, the most common form diabetes found in children is a condition in which the pancreas does not produce any insulin. The most common form of type 1 diabetes is caused by genetic mutation and some viruses.

As of today, there is no cure for type 1 diabetes. Treatment is focusing on managing blood sugar levels with insulin injection, diet, and lifestyle change.

* Type 2 diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose due to either cell in pancreas dying off or receptor sites clogged up by fat and cholesterol.

The most common symptoms of type 2 diabetes are an increased thirst that won't stop with water intake, increased hunger (especially after eating), dry mouth, frequent urination, and unintentional weight loss.

* Gestational diabetes is a form of diabetes that can occur during pregnancy, affecting between 3% and 20% of pregnant women.

Women with gestational diabetes are at an increased risk of type 2 diabetes in later life.

Hyperglycemia, a medical condition of abnormally high blood glucose, is a major concern, in people with both type 1 and type 2 diabetes.

Most cases of hyperglycemia occurred in patients who do not manage their diabetes properly.

Hyperglycemia, a hallmark of diabetes has been found to induce diabetics complications, including neuropathy, nephropathy, and retinopathy). ...

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential compound for the treatment of diabetes, researchers examined the association between the consumption of different types of vegetables in relation to T2D risk in an Asian Population.

Participants included in the study are 45 411 individuals (age range: 45-74 years) of the Singapore Chinese Health Study (SCHS) free of diabetes, cancer or CVD at baseline (1993-1998).

According to the dietary information collected using a validated FFQ and Physician-diagnosed incident diabetes reported at follow-up I (1999-2004) and II (2006-2010) interviews, 5207 incident T2D occurred during 494 741 person-years of follow-up.

However, after adjustment for potential confounders, total vegetables (top v. bottom quintile HR=1·08; 95 % CI 0·98, 1·18, P trend=0·66) nor specific vegetables including dark green leafy vegetables (HR=1·05; 95 % CI 0·96, 1·15, P trend=0·21) and cruciferous vegetables (HR=0·97; 95 % CI 0·88, 1·06, P trend=0·29) were not substantially associated with risk of T2D.

Another meta-analysis included eleven studies with 754 729 participants and 58 297 cases), suggested green leafy (summary relative risk (RR)=0·91; 95 % CI 0·84, 1·00) and cruciferous vegetable consumption (RR=0·87; 95 % CI 0·76, 1·00)  were borderline significant inverse associations between T2D risk, depending to types of vegetable intake.

Taken altogether, Cruciferous vegetables may be considered functional foods for the prevention of type 2 diabetes, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Green leafy and cruciferous vegetable consumption and risk of type 2 diabetes: results from the Singapore Chinese Health Study and meta-analysis by Chen GC1, Koh WP2, Yuan JM3, Qin LQ1, van Dam RM. (PubMed)

Broccoli Improves the Chemo Drug Cisplatin's Anti Cancer Activity

By Kyle J. Norton

A chemosensitivity assay is a test that measures the number of tumor cells killed by chemotherapy.

The aim of the test is to found the best chemo drugs for the treatment of cancer.

Cancer is a class of diseases in which a group of cells growing and multiplying disorderly and uncontrollably in our body.

Most cases of cancer start in the cells on the surface of the inner lining of specific tissues and organs.

At the early stage due to the very small size of the tumor, most cancers are asymptomatic. However, at the advanced stage, cancer not only can induce general symptoms such as gastrointestinal discomfort, unintended weight loss, fatigue, and loss but also lead to specific symptoms, such as localized bleeding and pain, depending on the location of cancer.

Also, at this stage, primary cancer cells can travel a distance away from the original site to infect other healthy tissues and organs, leading to secondary metastasis through the circulation of blood and fluids.

Some cancers can be slow-growth, including prostate and colon cancer. Primary cancer at stage 0 and 1 may not induce any symptoms.

According to the statistic provided by the American Cancer Society, in the US 2019, approximately 1,762,450 new cancer cases will be diagnosed and 606,880 deaths are results of cancer.

Furthermore, in the age perspective, older adults although are accounted for only 8% of all cases diagnosed in the US, have a 17% mortality rate compared to other age groups.

As of today, researchers do not know the exact cause of cancer neither they know why people with the same health condition and family history, some are susceptible to DNA alternation in facilitating the onset of cancer, while others do not.

The 5 years survival rate is totally depending on the stage of cancer diagnosed. The early diagnosed stage has the highest survival rate compared to other later stages.

Cisplatin is a chemotherapy drug given by Sclerotherapy used in conventional medicine for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, breast cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors, and neuroblastoma.

Cisplatin has been found to induce adverse effect, including nausea and vomiting, diarrhea, temporary hair loss, loss inability to taste the food, dry mouth, dark urine, and decreased sweating,

Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.

On finding a potential chemical compound with inhibition of chemotherapy side effects and chemosensitivity, researchers compared the effect of polymeric nanoparticles utilized to co-deliver a water-soluble CDDP derivative, poly(γ,l-glutamic acid)-CDDP conjugate and a naturally occurring compound derived from broccoli, sulforaphane (SFN) on chemo drug cisplatin (CDDP).

Compared with the combinational treatment of CDDP and SFN, the nanoparticles were more effectively internalized and significantly reduced GSH content in breast cancer cells, observed by the increase of DNA-bound Pt and DNA damage-induced apoptosis.

In other words, the combination is more effective than the use of the chemo drug alone due to its ability to penetrate deeper into the cancer cells.

Furthermore, in an orthotopic breast cancer model, the nanoparticles achieved a significantly higher tumor accumulation by enhancing the permeability and retention of EPR-mediated tumor targeting and exhibited a more powerful antitumor activity.

The nano-enhanced chemotherapy also showed higher content of GSH in the liver cancer model.

Collectively, researchers said, "this sulforaphane-based nano strategy holds great promise to enhance the sensitivity and therapeutic efficacy of Pt-based chemotherapy

Taken altogether, broccoli processed a high amount of sulforaphane used in a combination of chemo drugs may be considered adjunct therapy for the treatment of liver cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of sulforaphane in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity by Xu Y1,2,3, Han X1,2,4, Li Y1,2, Min H1, Zhao X1,2, Zhang Y1,2, Qi Y5, Shi J1,2, Qi S6, Bao Y7, Nie G. (PubMed)

Phytochemical Tocopherols, the Renal Protective Antioxidants

By Kyle J. Norton

The kidneys are a pair of kidney-shaped organs located on either side of your spine with a function to filter out the wastes from the blood before passing the wastes through urinary secretion.

More than a detoxed organ, the kidneys also maintain the body fluid balance, regulate the production of red blood cells and high blood pressure.

Kidney damage can be acute such as an overdose of toxin or chronic. Acute kidney diseases can be cured if the underlying cause is found.

Chronic kidney disease (CKD) is a slow and progressive disease that can lead to kidney failure over time.

At the advanced of CKD can cause the dangerous levels of fluid, electrolytes and wastes build up in the body.

Renal protection is a strategy that protects the kidney against injury or damage. In other words, renal protection is a process that maintains the function of the kidneys.

Depending on the severity of renal damage, patients may experience symptoms of decreased urine output, fluid retention, that lead to swelling in the legs, ankles or feet, fatigue, nausea, and physical weakness

In severe cases, patients may also have symptoms of shortness of breath, confusion, and irregular heartbeat.

The worse cases of kidney damage can lead to renal failure, a condition that induces wastes and toxins accumulated in the blood. In this stage, dialysis and kidney transplant are the only options.

According to statistics, approximately 14 percent of the US general population suffer from CKD. Believe it or not, more than 661,000 Americans have kidney failure. Of these, 468,000 individuals are on dialysis, and roughly 193,000 live with a functioning kidney transplant.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of kidney diseases, researchers examined the pretreatment effect of alpha-tocopherol against oxidative renal tubular damage and subsequent carcinogenesis by ferric nitrilotriacetate (Fe-NTA) in rats.

According to the tested analysis, injection of Fe-NTA in rats fed a standard diet showed an increase of renal mRNA levels of calnexin significantly in 3 hours of treatment-associated with the progression of chronic kidney disease (CKD) to end-stage renal disease.

After the injection of alpha-tocopherol, the levels of renal calnexin mRNA levels were decreased, without altering the protein levels.

In LLC-PK1 cells, the addition of alpha-tocopherol showed strong protective activity against oxidative stress induced by H2O2.

Furthermore, alpha-tocopherol induced N-acetylglucosaminyltransferase 3 involved in kidney cancer suppression.in the tested mice.

Moreover, alpha-tocopherol modifies glycoprotein metabolism partially induced cancer and inflammation by conferring mild ER stress in the protection against kidney cell damage.

Taken altogether, tocopherols may be considered a functional supplement for the prevention and treatment of kidney damage, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Alpha-tocopherol induces calnexin in renal tubular cells: another protective mechanism against free radical-induced cellular damage by Lee WH1, Akatsuka S, Shirase T, Dutta KK, Jiang L, Liu YT, Onuki J, Yamada Y, Okawa K, Wada Y, Watanabe A, Kohro T, Noguchi N, Toyokuni S. (PubMed)

Herbal Cramp Bark(Viburnum opulus), the Natural and Potential Gastroduodenoprotective Remedy

By Kyle J. Norton

The digestive system included the gastrointestinal tract, the liver, pancreas, and gallbladder plays a critical role to maintain the body normal function by providing nutrients and fluids to the body and remove waste through the secretary system.

The gastric mucosa is the mucous membrane layer of the stomach that plays a critical role in providing physical protection against ingested particles and preventing the contact between digestive enzymes such as pepsin and the underlying mucosa.

On the other hand, the gastric mucosal barrier protects the stomach against gastric acid that is required for digestion.

Dr, Lawson HH. in the classification of the different histologic types of the normal human duodenal mucosa suggested that there are antral type-duodenal mucosa, the transitional-type duodenal mucosa, and the jejunal-type duodenal mucosa.

The three different types of mucosa vary in their degree of susceptibility to the effect of acid hypersecretion, leading to duodenitis and gastritis and worsens the condition of ulcer.

The function of duodenum mucosa is to increase its surface area that contacts with chyme passing through the intestinal lumen and improves the absorption of nutrients.

Abnormal duodenal mucosa can lead to acute and chronic duodenal ulcers.

Cramp Bark is an ornamental plant, genus Viburnum, belonging to the family Adoxaceae, native to Europe and Asia. It has been used in traditional and herbal medicine as anti-spasmodic, anti-inflammatory, nervine. hypotensive agent and to treat menstrual cramps and pain, afterbirth, postpartum pains, excessive blood loss in periods, bleeding associated with the menopause, etc.

On finding a potential herbal medicine for the protection of the digestive function, researchers examined the gastrointestinal mucosal defense mechanisms of proanthocyanidins (PA), the polymers of flavan-3-ols, isolated from the Viburnum opulus (VOPA, Caprifoliaceae).

According to the tested assays of rats exposed to non-topical ulcerogens (stress) without and with capsaicin (125 mg/kg, sc) denervation, VOPA showed strong effects in the promotion of the gastroduodenal mucosal integrity and pattern, observed by the carbohydrate-binding proteins and nitric oxide (NO) content that protects the intact mucosa.

The levels of antioxidant enzymes produced by the tested rats such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) were also significantly higher in the VOPA group at doses of 25, 50 or 75 mg/kg body weight.

In other words, VOPA inhibited lipid peroxidation by enhancing the production of antioxidant enzymes produced by the host.

Based on the findings, researchers said, "VOPA exerts a potent gastroduodenoprotective activity via an increase in endogenous NO generation, suppression of lipid peroxidation and mobilization of antioxidant activity and changes in glycoconjugate content of the gastroduodenal mucosa of rats".

Taken altogether, cramp bark(Viburnum opulus)  may process the gastroduodenoprotective effects, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Influence of Viburnum opulus proanthocyanidins on stress-induced gastrointestinal mucosal damage by Zayachkivska OS1, Gzhegotsky MR, Terletska OI, Lutsyk DA, Yaschenko AM, Dzhura OR. (PubMed)
(2) The duodenal mucosa in health and disease. A clinical and experimental study by Lawson HH. (PubMed)

Omega-3 Fatty Acids Lower Blood Pressure in Children Born with Reduced Birth Weight

By Kyle J. Norton

Blood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.

Hypertension or high blood pressure is a condition characterized by persistent high blood pressure.

In the US approximately, one-third of the adults have high blood pressure, affecting over 77 million people in the country. 

Additionally, among adults age 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.

High blood pressure is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.

High blood pressure can be acute or chronic. Acute high blood pressure most often occurs to people with sudden stress.

Acute high blood pressure can be caused by intense physical exercise. As the heart must pump harder to provide the needs of nutrients and oxygen.

Most cases of chronic high blood pressure are associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.

In other words, if you can control your diet, such as making changes to lifestyle, maintaining ideal weight and diet with low salt, you could do just fine without the drugs.

The cause of high blood pressure is a result of hardening and thickening of the arteries (atherosclerosis), due to the slow progression of plaques accumulated on the wall of the arteries.

According to the American Heart Association (AHA) patients with blood pressure that higher than 130 over 80 millimeters of mercury (mmHg) is considered to have hypertension.

Untreated chronic high blood pressure may induce complications of heart attack, stroke, and other health conditions.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of cardiovascular diseases, researchers examined the associations of dietary intake in childhood of the long-chain ω-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid with blood pressure parameters in children born with reduced birth weight.

According to the results from the data from 3457 children aged 8 to 15 years participating in the continuous National Health and Nutrition Examination Survey 2003-2004, 2005-2006, and 2007-2008, compared to normal birth weight children, systolic blood pressure was 1.1 mm Hg higher in those with reduced (<10th centile).

More importantly, at the baseline,  reduced (<10th centile) birth weight children showed a higher systolic blood pressure of 1.1 mm Hg, compared with normal birth weight (≥ 10th centile) children.

Compared with children with the lowest tertile of intake, 354 children with reduced birth weight, with the highest tertile of dietary eicosapentaenoic acid and docosahexaenoic acid intake showed a significantly lower systolic blood pressure (-4.9 mm Hg [95% confidence interval, -9.7 to -0.1]) and pulse pressure.

In other words, high-dietary intakes of eicosapentaenoic acid and docosahexaenoic acid are associated with lower systolic blood pressure and pulse pressure in children born with reduced birth weight. 

Based on the findings, researchers said, "These data are consistent with the hypothesis that long-chain ω-3 fatty acids reduce blood pressure in those with impaired fetal growth".

 Taken altogether, Omega-3 fatty acids lower blood pressure, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) High intake of dietary long-chain ω-3 fatty acids is associated with lower bloodpressure in children born with low birth weight: NHANES 2003-2008 by Skilton MR1, Raitakari OT, Celermajer DS. (PubMed)

Cranberry Inhibits the Biofilms Growth of Candida Albicans

By Kyle J. Norton

A fungus is a primitive organism, including mushrooms, mold, and mildew.found in the air, in the soil, on plants, and in water.

Fungi reproduce through tiny spores in the air to cause a fungal infection that often starts in the lungs or on the skin.

Similar to other bacterias, there are millions of different fungal species on Earth, but only about 300 are known to infect people.

Conventionally, fungal infection is treated with antibiotics, including topical antifungal ointments or oral medications, depending on the severity of the disease.

Candida is a class of yeasts that cause fungal infections worldwide.

Candida albicans is a member of a large group of an organism whose cells contain complex structures enclosed within the membranes, including yeast and mold that live among the gut flora in the human mouth and gastrointestinal tract.

Under normal circumstances, Candida albicans do not cause harmful effects, but overgrowth results in candidiasis.

Oral candidiasis is an oral condition infected by the fungal C. albicans found mostly in people with a weakened immune system including patients who are taking the immune-suppressive medicine.

Biofilms are microbial communities in which cells stick to each other and often also to a surface.

Symptoms of oral Candida overgrowth include worse in the damp day, persistence drowsiness, lack of coordination, headaches, mood swing, loss of balance, rashes, bad breath, dry mouth, and postnasal drip.

There are many risk factors associated with Candida overgrowth including medical conditions that cause weakened immune system, inhalant medicine, low level of stomach acids, and pregnancy.

Some researchers suggested aging may be one of the major risk factors that cause Candida overgrowth

Dr. Aikaterini Flevari, the lead scientists said, "Candida species remain the most important cause of opportunistic infections worldwide, affecting predominantly patients over 65 years old, while they are considered to be the fourth most common cause of nosocomial bloodstream infections".

And, "The rapidly growing elderly population has specific physiological characteristics, which makes it susceptible to colonization and subsequent infection due to Candida species".

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia.

 Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the treatment of infectious disease, researchers examined the effects of polyphenol-rich cranberry extracts on dual-species Streptococcus mutans-Candida.

The experience included S. mutans-C. albicans biofilms grown on saliva-coated hydroxyapatite discs (s-HA) mounted on the high-throughput Amsterdam Active Attachment model treated by the cranberry extracts/vehicle control for five minutes just before biofilm growth and subsequently after 12 hours and 24 hours of biofilm growth.

According to the tested analysis, cranberry extracts treatment after 24-hour-old biofilms at doses of 500 to 1,000 μg/mL significant reduce acidogenicity and metabolic activity (P<0.0001) compared to the control.

Furthermore, cranberry extracts treatment also showed a significant decrease in biovolumes of the exopolysaccharide (EPS) and microbial biofilm components.

Based on the findings, researchers said, "Cranberry extracts inhibited cariogenic virulence properties of S. mutans-C. albicansdual-species biofilms in an in vitro model".

Taken altogether, cranberry may be considered a remedy for the treatment of Candida albicans, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Polyphenol-Rich Cranberry Extracts Modulate Virulence of Streptococcus mutans-Candida albicans Biofilms Implicated in the Pathogenesis of Early Childhood Caries by Philip N1, Leishman SJ2, Bandara H3, Walsh LJ. (PubMed)
(2) Cranberry-derived proanthocyanidins induce a differential transcriptomic response within Candida albicans urinary biofilms by Sundararajan A1, Rane HS2, Ramaraj T1, Sena J1, Howell AB3, Bernardo SM4, Schilkey FD1, Lee SA. (PubMed)