Turnip, the Anti-Hypoxia Herbal Remedy

By Kyle J. Norton

Hypoxia is an urgent medical emergency of deficiency in the amount of oxygen reaching the tissues.

In other words, if your body does not get enough oxygen, you might get hypoxia. The condition has been found to induce brain, liver, and other organs damaged just minutes after symptoms starting.

The most common symptoms of hypoxia are associated with a lack of oxygen that reaches the organs and tissues, including changes in the color of the skin, ranging from blue to cherry red, confusion, cough, increased heart rate, rapid breathing and shortness of breath.

Most common risk factors associated with the onset of hypoxia are damage to lung due to trauma, medical conditions as an asthma attack, lung diseases such as chronic obstructive pulmonary disease (COPD), emphysema, bronchitis, pneumonia, and pulmonary edema, intake of certain medications that hold back breathing and people with severe anemia.

The most common treatment of hypoxia is to withdraw medications that cause the condition and give additional oxygen to the patient quickly. Almost all patients respond to additional oxygen supplied by a nasal cannula.

Tibetan turnip (Brassica rapa L.), native in Tibet region, is a medical plant used in Tibet as a “tonic and anti-hypoxia” “heat-clearing and detoxification” and “alleviating fatigue” herbal medications.

On finding a potential compound for the treatment of hypoxia, researchers conducted a joint study led by Zhejiang University on an animal model.

Selected male ICR mice included in the study were assigned to the normoxia group and several hypoxia groups, given sterile water, p-coumaric acid (CA) or dexamethasone orally, once daily for four consecutive days.

Based on the results of the analysis in a hypoxic environment of 9.5% O2,, mice treated with 100 mg/kg body wt CA showed a significantly lower lung water content (LWC), and the protein content of bronchoalveolar lavage fluid (BALF) content than mice in the hypoxia vehicle group.

Where lower lung water content (LWC), and the protein content of bronchoalveolar lavage fluid (BALF)content are the symptoms of the deficient amount of oxygen in the lung.

Moreover, mice treated by CA also protect the lung functioning by showing an intact lung blood-gas-barrier, increased levels of plasma total NO, 

Additionally, levels of preproendothelin-1 (PPET1), associated with the vasoconstriction was also decreased in the CA treatment group.

More importantly, CA induced the production of occludin, a tight junction protein in maintaining the integrity of the lung epithelial barrier against hypoxia.

Taken altogether, turnip may be considered herbal medicine for the prevention and treatment of hypoxia, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) p-Coumaric acid as a prophylactic measure against normobaric hypoxia-induced pulmonary edema in mice by Li Y1, Han J1, Chen Y1, Chen C1, Chu B2, Zhang Y. (PubMed)

Brassica Food plants in the Prevention and Treatment of Cardiac Hypertrophy

By Kyle J. Norton

Hypertrophy is a process or condition that increases and growth of muscle cells by increasing the muscular size achieved through exercise.

Lifting weights are the most common way to increase hypertrophy.

In other words, hypertrophy is the enlargement of an organ or tissue from the increase in the size of its cells by increasing the number of contractile proteins in each muscle fiber.

There are two types of muscular hypertrophy including the growth of muscle contraction parts or myofibrillar and the increased muscle glycogen storage or sarcoplasmic.

Myofibrillar training improves the strength and speed, compared to sarcoplasmic growth that sustains more energy in endurance athletic events.

Cardiac hypertrophy is a medical condition associated with the abnormal enlargement, or thickening, of the heart muscle.

The most common causes of cardiac hypertrophy are the results of hypertension or valvular disease.

The condition can also be caused by athletic hypertrophy (a condition related to exercise), valve disease, hypertrophic cardiomyopathy (HOCM), and congenital heart disease.

The most common symptoms are shortness of breath, chest pain, and palpitation, especially during exercise.

On finding a potential compound that attenuates cardiac H9c2 cell hypertrophy, researchers examined the effects of 3,3'-Diindolylmethane (DIM) is the major product of the acid-catalyzed condensation of indole-3-carbinol (I3C), a component of extracts of Brassica food plants.

The study was conducted using an in vitro model with 1 µM angiotensin II (Ang II) in cultured rat cardiac H9c2 cells, to observe the effects of DIM on cardiac hypertrophy.

According to the tested analysis, the optimal concentration of DIM for 6, 12, and 24 h. showed a significant effect on the atrial natriuretic peptide, brain natriuretic peptide, and myosin heavy chain β mRNA expression induced by Ang II in H9c2 cells.

In other words, DIM lower the blood pressure, promotes diuresis, natriuresis, vasodilation of the systemic and pulmonary vasculature, and reduction of circulating levels of endothelin and aldosterone and cardiac muscle contraction induced by Ang II in H9c2 cells.

Furthermore, H9c2 cells treated with DIM for 0, 15, 30, and 60 min induced by Ang II also improve the function of 5'-AMP-activated protein kinase catalytic subunit alpha-1 that regulates the activities of a number of key metabolic enzymes in protecting the cardiac cells from stresses in response to hypertrophic stimuli.

Based on the findings, Brassica food plants consist of DIM that may be used for the prevention of cardiac hypertrophy, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) 3,3'-Diindolylmethane attenuates cardiac H9c2 cell hypertrophy through 5'-adenosine monophosphate-activated protein kinase-α by Zong J1, Wu QQ1, Zhou H1, Zhang JY1, Yuan Y1, Bian ZY1, Deng W1, Dai J1, Li FF1, Xu M1, Fang Y1, Tang QZ. (PubMed)

Lycopene Inhibits the Onset of Chronic Bacterial Prostatitis, According to Studies

By Kyle J. Norton

Prostatitis is a condition associated with the inflammation of the prostate and the areas around the prostate.

Chronic bacterial prostatitis is a medical condition of prostatitis induced by a bacterial infection.

According to the statistics provided by the American Family Physician, approximately 8.2 percent of men in the US are living with prostatitis. The conditions account for 8 percent of visits to urologists, and up to 1 percent of visits to primary care physicians.

Believe it or not, in 2000, prostatitis has cost over $84 million, including the charge of diagnosis and treatment.

The most common symptoms of prostatitis are painful, difficult and/or frequent urinating, groin pain, rectal pain, abdominal pain and/or low back pain, fever, chills, and body aches.

In severe cases, patients may also experience symptoms of urethral discharge, painful ejaculation or sexual dysfunction and blood in the urine.

The exact causes of prostatitis are not identified, some researchers suggested that nerve damage in the lower urinary tract caused by surgery or trauma to the area has been found to induce prostatitis in patients.

Conventionally, most cases of prostatitis are treated by antibiotics in cases of infection, alpha-blockers to relax the bladder neck and the muscle fibers and anti-inflammatory medicine to ease pain and discomforts.

Dr. JAMES J. STEVERMER, the lead scientist in the treatment of chronic bacterial prostatitis at the University of Missouri–Columbia School of Medicine, wrote, "If the patient responds to therapy, antibiotics are continued for at least three to four weeks, although some men require treatment for several months. A patient who does not respond might be evaluated for chronic nonbacterial prostatitis, in which nonsteroidal anti-inflammatory drugs, alpha-blocking agents, anticholinergic agents or other therapies may provide symptomatic relief".

Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.

On finding a potential compound for the treatment of prostatitis, researchers evaluated the efficacy and the safety of a combination of Serenoa repens, selenium and lycopene extract + bromelain and methylsulfonylmethane extract associated with levofloxacin in patients with chronic bacterial prostatitis (CBP).

The study included all patients with a clinical and instrumental diagnosis of CBP, admitted to a single Urological Institution from March to June 2015 were enrolled in this phase III study. 

All selected patients were randomized into two groups, Group A (n=40)received levofloxacin 500 mg o.d. for 14 days associated with lycopene and methylsulfonylmethane; Group B (n=39) received levofloxacin (500 mg o.d. for 14 days) only.

According to the results from the follow-up (T1), the NIH Chronic Prostatitis Symptom Index (CPSI), International Prostatic Symptom Score (IPSS) of group A were significantly lower compared to group B.
In other words, group A showed milder symptoms compared to group B.

Furthermore, the symptomatic and microbiological recurrence was also significantly lower in group A n=1) compared to group B (n=7).

Moreover, these change between groups was continued at the second follow-up visit (T2) observed by the questionnaire results.

Based on the findings, researchers said, "The combination of Serenoa repens, selenium, lycopene + bromelain and methylsulfonylmethane extracts improved the clinical efficacy of levofloxacin in patients affected by CBP without the development of side effects".

Taken altogether, lycopene found in tomato may be considered an adjunct therapy for the treatment of chronic bacterial prostatitis, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You.  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Serenoa repens associated with selenium and lycopene extract and bromelain and methylsulfonylmethane extract are able to improve the efficacy of levofloxacin in chronic bacterial prostatitis patients by Cai T1, Tiscione D, Gallelli L, Verze P, Palmieri A, Mirone V, Bartoletti R, Malossini G. (PubMed)
(2) Treatment of Prostatitis by JAMES J. STEVERMER, M.D., M.S.P.H., and SUSAN K. EASLEY, M.D. (the University of Missouri–Columbia School of Medicine, Columbia, Missouri)

Cranberry Protects the Neurons Against β-Amyloid Aggregation

By Kyle J. Norton

Amyloid beta (Aβ or Abeta) is the main component of the amyloid plaques that cause the gradual death of neurons, leading to the onset of Alzheimer's disease.

Alzheimer's disease is a common form of dementia or neurodegenerative disease found in the elderly.

Alzheimer's disease is a type of dementia correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.

According to the statistics, the disease is most prevalent in the elderly. Approximately 5.7 million Americans of all ages are living with Alzheimer's. 15.9 million family caregivers provide an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.

 Alzheimer's disease is caused by a combination of genetic, lifestyle and environmental factors that affect the neurons of the brain over time. However, less than 10% of patients with AD are associated with a genetic preposition. Patients with such mutated genes on chromosomes 21, 14, and 1are virtually guaranteed to develop the disease.

More precisely, Alzheimer's disease is caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.

Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal.

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia.

 Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the treatment of mental disorders, researchers examined the effect of cranberry supplementation on β-amyloid aggregation.

According to tested analysis, the cranberry protected the neurons by mediating Aβ toxicity alleviation required heat shock transcription factor (HSF)-1 rather than DAF-16 and SKN-1associated with cellular stress.

In other words, cranberry supplementation reduced Aβ toxicity induced brain cell stress by reducing the transactivity of HSF-1 in an IIS-dependent manner.

More precisely, HSF-1 plays a pivotal role in maintaining proteostasis, a process that regulates proteins within the cell in order to maintain the neuron cellular health involved in oxidative stress.

Based on the findings, researchers aid, "(cranberry) elucidated the mechanism whereby cranberry attenuated Aβ toxicity in C elegans and stressed the significance of proteostasis in the prevention of age-related diseases from a practical point of view.".

Taken altogether, cranberry may be considered a remedy for the treatment of AD, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberry Extract Standardized for Proanthocyanidins Alleviates β-Amyloid Peptide Toxicity by Improving Proteostasis Through HSF-1 in Caenorhabditis elegans Model of Alzheimer’s Disease by
Hong Guo, Min Cao, Sige Zou, 4 Boping Ye,  and Yuqing Dong. (PMC)

Herbal Ashwagandha Balance the Ratio of Antioxidants and Free Radicals Against the Onset of Oxidative Stress

By Kyle J. Norton

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, intake dietary sources of antioxidants may be necessary.

Oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.

In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.

Dr. Ercal N, the lead author in the study of the relation of toxic metals and oxidative stress, wrote, "antioxidants may play an important role in abating some hazards of heavy metals. In order to prove the importance of using antioxidants in heavy metal poisoning, pertinent biochemical mechanisms for metal-induced oxidative stress".

There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, oxidative burst from activated macrophages, particularly, the free radicals chain reaction.

Sadly, a prolonged period of oxidative stress presented in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.

Certain chronic diseases are found to be associated with oxidative stress, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, and stroke.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound that processes the antioxidant activity, researchers examined  the acetylcholine esterase (AChE) inhibitory and antioxidant potential of Ashwagandha root extract (ARE

Ashwagandha root extract (ARE) in in-vitro and ex-vivo models showed a strong free radical scavenging effect by preventing protein degradation.

In rat lymphocytes, ARE pre-treatment not only protect the immune cells's integrity against s against H2 O2 -induced oxidative damage including DNA fragmentation and significantly decreased the activities of key antioxidant enzymes such as peroxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glucose-6-phosphate dehydrogenase.

Furthermore, the decreased and increased the content of glutathione and malondialdehyde induced by the injection H2O2 have also reversed,  indicating by the remedy to suppress hydrogen peroxide-induced oxidative stress.

Collectively, researchers said, "The study provides the scientific basis of pleiotropic functions of Ashwagandha".

Taken altogether, Ashwagandha may be considered a functional herb for the treatment of chronic diseases induced by oxidative stress, pending to the result of larger sample size and multicenter study

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Ashwagandha Root Extract Inhibits Acetylcholine Esterase, Protein Modification and Ameliorates H2 O2 -Induced Oxidative Stress in Rat Lymphocytes by Ajay Pal1 , Kandikattu Hemanth Kumar2 , Bharat Bhushan*1, Vinod Saharan (Pharmacogn J. 2017; 9(3):302-309A Multifaceted Journal in the field of Natural Products)
(2) Toxic metals and oxidative stress part I: mechanisms involved in metal-induced oxidative damage by Ercal N1, Gurer-Orhan H, Aykin-Burns N.(PubMed)

Herbal Coltsfoot(Tussilago farfara) Induces Expectorant Effect in Vivo

By Kyle J. Norton

An expectorant effect is a function that helps to cough up loosen mucus by increasing the water content.

Coughing is a natural reflex that clears the throat of mucus or foreign pathogens.

In other words,  frequent coughing may be a condition of infection caused by inflammation of the airway. 

An acute cough is short-term coughing that lasts for less than three weeks. Chronic coughing that lasts more than 3 weeks may be a condition of respiratory diseases, including asthma, allergies, gastroesophageal reflux disease (GERD), or bronchitis.

Phlegm produced in the lungs and lower respiratory tract is a type of mucus found mostly in acutely sick or longstanding health conditions patients.

Chronic mucus collected in the lungs has been associated with patients with tuberculosis (TB), pneumonia, a fungal infection, whooping cough early in life and measles.

Seriously, chronic mucus collected in the lungs increases a significant risk of further infections and more damage.

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.

The Modern Research Center for Traditional Chinese Medicine of Shanxi University, the expectorant effect of Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae) examined the water extracts orally from flower bud and rachis that administrated to tested mice.

Mice selected to the study induced coughing by Ammonia showed a strong effect on significantly lengthened the latent period of cough, decreased cough frequency.

Furthermore, in expectorant evaluation, the phenolic compounds, organic acid, sugar, amino acid, terpene, and sterol were found to be the major contribution in enhancing tracheal phenol red output.

Additionally, in chemical analysis, the high concentration of chlorogenic acid, 3,5-dicaffeoylquinic acid, rutin in flower buds showed a significant antitussive and expectorant effects of Flos Farfara compared to flower rachis.

Dr. Li ZY, the lead scientist said, "These findings provide pharmacological and chemical evidence that only flower bud can be used as the antitussive and expectorant herbal drug".

Taken altogether, coltsfoot may be considered a remedy for loosening mucus, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Metabolomic profiling of the flower bud and rachis of Tussilago farfara with antitussive and expectorant effects on mice by Li ZY1, Zhi HJ, Xue SY, Sun HF, Zhang FS, Jia JP, Xing J, Zhang LZ, Qin XM. (PubMed)

Turmeric Processes Anti-Metastatic Activity

By Kyle J. Norton

Cancer is a class of diseases characterized by the irregular cell growth on the body tissue, due to the alternation of cell DNA.

Most cases of cancer start in the cell on the surface of the inner lining tissue and do not exert any symptoms at the early stage.

At the later stage, the larger size tumor may press on the nearby blood vessels and nerve cells, causing localized severe bleeding and pain accompanied by the general symptoms of cancers, including the unintended weight loss, loss of appetite, fatigue and tiredness and gastrointestinal problems.

Most cancer cells at this stage can also travel a distance away from the original site to affect other healthy tissue and organs, leading to secondary metastasis.

Metastasis is the process to induce the development of secondary malignant growths at a distance from primary cancer.

Metastatic cancer also shares the characteristics of primary cancer. Breast cancer that spreads to the lung is called metastatic breast cancer, not lung cancer.

According to statistics, in 2018, approximately over1,700,000 cases of cancer were diagnosed worldwide. The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.

Believe it or not, some metastatic cancer may have an unknown primary origin or CUP, secondary cancer without a primary cancer site.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

In the urgency to discover a natural ingredient for the prevention of metastasis in cancer, researchers examined the effects of Furanodiene, a bioactive compound isolated from Curcuma wenyujin Y. H. Chen et C. Ling (C. wenyujin) on tumor metastatic activities.

According to the tested differentiation, low concentrations (5-25μM) of furanodiene inhibited adhesion, migration, and invasion of breast cancer cells, without inducing cytotoxicity, apoptosis and cell cycle arrest.

Furthermore, furanodiene also regulated the parameters such as the integrin αV expression, β-catenin expression, associated with the cell survival, migration, proliferation, differentiation, angiogenesis, and remodeling of the extracellular matrix in the modulation of the tumor metastasis process.

In MDA-MB-231 cells, furanodiene modulated the matrix metalloproteinase 9 (MMP-9) involved in tumor metastasis and cancer markers.

Based on the results Dr. Zhong Z, the lead scientist said, "furanodiene might be the primary contributor to the anti-cancer effects of volatile oil extracts, and it might be a good therapeutic target for highly metastatic breast cancer".

Taken altogether, turmeric processed a high amount of bioactive compound furanodiene may be considered supplements for the prevention of tumor metastasis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Furanodiene, a natural small molecule suppresses metastatic breast cancer cell migration and invasion in vitro by Zhong Z1, Tan W1, Chen X2, Wang Y. (PubMed)