Friday, 27 September 2019

Green Beans Inhibit the Expression of Liver Stress Markers

By Kyle J. Norton

Oxidative stress is a condition characterized by overexpression of free radicals in the body.

In other words, oxidative stress is a result of the imbalance of the ratio of free radical and antioxidant caused by abundant free radicals and low levels of antioxidant enzymes produced by the body.

Free radical is an unstable atom with a single electron on the outermost ring. Given to its nature, free radicals readily donate or intercept an electron from another atom, leading a chain of the free radical cascade which cannot be stopped until all single electron is paired or inhibited by antioxidants.

Antioxidants are stable atoms with a function to inhibit oxidation, come either from dietary sources or produced by the body.

Contrast to general belief, free radical is also needed in a moderated amount for the function of the heart muscle to pump blood such as NO for vasodilation and increasing blood flow.

In a healthy person, oxidative stress is harmful because it not only induces cells lipid and protein oxidation but also causes the change of cell DNA, leading to diseases associated with oxidative stress including cancer, diabetes, and cardiovascular disease.

Ozone, certain pesticides, and cleaners, cigarette smoke, radiation, pollution are some of the risk factors associated with the increased risk of oxidative stress.

Liver stress markers such as serum MDA refer to oxidative stress in the liver tissues caused by the overexpression of free radicals or reduced levels of antioxidant enzymes in the liver.

Dr. Halina Cichoż-Lach, the lead scientist said, "Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases.".

And, "Hepatocytic proteins, lipids, and DNA are among the cellular structures that are primarily affected by ROS and reactive nitrogen species. The process results in structural and functional abnormalities in the liver".

In other words, liver oxidative stress over the long-term induced damage of proteins, and lipid and alternation of cell DNA can lead to liver diseases, including cancer.


Green bean is a genus of Phaseolus Sensu Stricto, containing 55 difference species, belong to the family Fabaceae and native to the New World tropics and grown in Europe for its attractive flowers and fleshy immature pods. It can be classified into two major groups, bush beans, and pole beans.

On finding a natural compound for the prevention liver stress, researchers examined the effect of cabbage, green beans, or seeds from sunflowers grown either on municipal sewage sludge-amended soil or soil alone fed to male and female Coturnix quail, as 50% of a complete diet, for 5 weeks.

Green beans fed male and female Coturnix quail exhibited liver GST activities significantly lower comapred those fed with sludge-grown cabbage.

Comapred to the levels of liver glutathione S-transferase (GST) soil-grown cabbage demonstrated a two-fold activity increase in birds fed the other plants.

More precisely, the levels of glucosinolates present in the cabbage, are 3040 and 9253 ppm (dry basis) in the sludge-grown and soil-grown cabbage, respectively.

In other words, green beans showed a significant reduction of liver stress markers lesser than those of cabbage, regardless of soil cultivation.

Taken altogether, green beans may be considered a liver protective veggie, pending to the confirmation of larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Changes in liver glutathione S-transferase activities in Coturnix quail fed municipal sludge-grown cabbage with reduced levels of glucosinolates by Stoewsand GS, Anderson JL, Lisk DJ. (PubMed)
(2) Oxidative stress as a crucial factor in liver diseases by Halina Cichoż-Lach and Agata Michalak (PMC)

Thursday, 26 September 2019

Bromelain, the Potential Treatment of Chronic Rhinosinusitis

By Kyle J. Norton

Rhinosinusitis (RS) is a condition associated with the inflammation of the sinuses and nasal cavity.

Sinusitis is an inflammation of the paranasal sinuses that causes a headache as a result of exposure to a cold or flu virus, or an allergic reaction to pollen, mold, dust or smoke.

Sinusitis affects 37 million people each year.

Other symptoms of RS include nasal congestion or obstruction, facial or dental pain, purulent rhinorrhea, postnasal drainage, headache, and cough. 

Some patients may also experience symptoms of fever, fatigue, hyposmia, ear fullness or pressure,  voice changes, epiphora, fever, and psychological effects and fatigue.

If you have some of the above symptoms that last more than 12 weeks, you may have chronic rhinosinusitis,

If you experience some of the aforementioned symptoms without a cold or flu, you may have rhinosinusitis. Conventionally, most cases of bacterial rhinosinusitis (BRS) are treated by antibiotics.

In viral rhinosinusitis (VRS), medication focus on reducing symptoms and improving quality of life.
Out of many risk factors involved in the onset of the condition, some researchers suggested that people with an immune deficiency may be vulnerable to rhinosinusitis developing.

Dr. Sergio E. Chiarella, the lead scientist wrote, "CRS is a common disease; in those patients with frequent exacerbations or who are refractory to treatment, an immunodeficiency evaluation should be considered. Treatment includes vaccination, antibiotic therapy, immunoglobulin replacement, and surgery".

More precisely, people who are using immune suppressants or weakened and immature immune system are at an increased risk of rhinosinusitis.


Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

With an aim to find a natural compound for the treatment of an inflammatory condition associated with sinuses and nasal cavity, researchers examined the bromelain effects on patients with chronic rhinosinusitis (CRS).

40 patients including 20 patients were given bromelain 500 mg tablet twice daily for 30 days, and 20 controls enrolled in the study.

According to the observation in the turbinate and ethmoid mucosas and in the serum of both the groups, bromelain showed significant anti-inflammatory activity in paranasal sinus pathologies.

In other words, the efficacy of bromelain anti chronic rhinosinusitis was attributed to its function in distribution evenly in the sinuses and nasal cavity.

Taken altogether, bromelain may be considered supplements for the prevention and treatment of chronic rhinosinusitis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Bromelain's penetration into the blood and sinonasal mucosa in patients with chronic rhinosinusitis by Passali D1, Passali GC2, Bellussi LM1, Sarafoleanu C3, Loglisci M1, Manea C3, Iosif C4, Passali FM. (PubMed)
(2) Alternative therapies for chronic rhinosinusitis: A review by Griffin AS1, Cabot P, Wallwork B, Panizza B. (PubMed)
(3) Immune deficiency in chronic rhinosinusitis: screening and treatment by Sergio E. Chiarella and Leslie C. Grammer. (PMC)

Lycopene Protects the Lung Against Chronic Obstructive Lung Diseases (COPD)

By Kyle J. Norton

The lungs are a pair of organs located on either side of the chest (thorax) with a function to bring fresh oxygen into the body and remove the carbon dioxide and other waste gases from the body.

According to the statistics provided by the Lung Association over 3 million Canadians are affected by one of five serious respiratory diseases – asthma, chronic obstructive pulmonary disease (COPD), lung cancer, tuberculosis (TB), and cystic fibrosis.

In 2017, 28,600 Canadians were diagnosed with lung cancer, represented 14% of all new cancer cases. Lung cancer caused the death of 21,100 Canadians in the same year.

The exact causes of lung disease are not identified. However, epidemiological studies suggested
being overweight, smoking, family history, smoking are some of the most prevalent factors associated with the onset of the disease.

Most common lung diseases in North America including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, pulmonary hypertension, and cystic fibrosis.

Symptoms of lung disease are totally depending on the type of disease.

Most common diseases associated with allergic airway inflammation are
* Asthma is a chronic inflammatory disease affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood.

*Chronic obstructive pulmonary disease (COPD), the third leading cause of death in the US can be classified into
** Emphysema casued by damage to tissues of the air sacs (alveoli) in the lungs is a type of chronic obstructive pulmonary disease (COPD)associated with a long term and progressive condition cause of shortness of breath but depending to the stage of lung function.


** Chronic bronchitis is a chronic inflammation of the lung’s bronchi that causes the increased production of mucus in the lung induced symptoms of difficulty breathing.


Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and perform various functions in photosynthesis.

On finding a potential compound for the treatment of asthma researchers examined the effects of ascorbic acid (AA), carotenoids (lutein, zeaxanthin, β-cryptoxanthin, α-carotene, β-carotene, and lycopene), retinol and α-tocopherol levels in Japanese patients with chronic obstructive lung diseases (COPD).

Based on the tested analysis, comapred to other phytochemicals, plasma AA level was significantly lower in of COPD subjects than that of healthy elderly people. 

Levels of plasma lycopene and total carotenoid levels associated with levels of antioxidant enzymes such as GSH content produced the host were significantly lower in COPD subjects comapred to those of healthy elderly people without affecting the redox markers such as GSSG, GSH/GSSG ratio associated with the oxidative stress in the lung tissues.

Lycopene and total carotenoid levels did not lower the marker of the levels of urinary 8-OHdG detected in COPD subjects compared to healthy elderly people.

In other words, increased the levels of lycopene and total carotenoid levels in the body may have a strong impact in reducing the risk of COPD


Based on the findings, researchers said, "COPD of Japanese patients may develop partly because of oxidative stress derived from a shortage of antioxidant nutrients, especially of AA and lycopene".

Taken altogether, lycopene found in tomato may be considered a remedy for the prevention of COPD, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You.  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antioxidant nutrients in plasma of Japanese patients with chronic obstructivepulmonary disease, asthma-COPD overlap syndrome and bronchial asthma by Kodama Y1, Kishimoto Y2, Muramatsu Y3, Tatebe J4, Yamamoto Y5, Hirota N3, Itoigawa Y1, Atsuta R1, Koike K1, Sato T1, Aizawa K5, Takahashi K1, Morita T4, Homma S3, Seyama K1, Ishigami A. (PubMed)

Wednesday, 25 September 2019

Herbal Coltsfoot(Tussilago farfara) Improves the Bone Marrow Cells Against the Risk of Leukemia

By Kyle J. Norton

Leukemia is a condition characterized by an abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending to the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.

Bone marrow is soft tissue inside the hollow center of the major bone. including spine, pelvis, underarm, leg. etc.

Acute leukemia is a condition caused by a rapid increase in the numbers of extreme immature white blood cells which appear in the bloodstream in the other parts of the body, including tissue and organs, Acute leukemia can also be classified into
* Acute lymphoblastic leukemia (ALL)
Acute lymphocytic leukemia (ALL) is a type of cancer of the abnormal growth of extreme immature lymphocytes overproduced by the bone marrow and/or lymphatic system. The condition has a tendency to multiply quickly, leading to the death to normal white blood cells in the bone marrow and/or lymphatic system.

In ALL, lymphocytes appear immature in the bloodstream. Acute lymphoblastic leukemia (ALL) is the most common children forms of leukemia with about 80% of all cases.

* Acute myeloid leukemia (AML)
Acute myelogenous leukemia (AML) is a cancer of myelogenous lining caused by the rapid growth of abnormal granulocytes accumulated in the bone marrow, interfering with the normal blood cells. In AML, granulocytes appear immature in the bloodstream.

According to the statistic proved by the American Cancer Society, in 2019, approximately 21,450 new cases of acute myeloid leukemia (AML) will be diagnosed in adults. The disease also causes the
of 10,920 deaths of American adults.

Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.

On finding a potential compound for the treatment of bone marrow cells integrity, researchers examined the protective effect of polysaccharides from Tussilago farfara L. on bone marrow cells.

According to the tested analysis, Tussilago farfara L. protected the bone marrow cells against the side effects of polychemotherapy-induced apoptosis.

Furthermore, polychemotherapy-induced DNA damage in bone marrow cells was also reversed by the application of polysaccharides from Tussilago farfara L.

In vivo, small intestinal epithelium of C57Bl/6 mice, polysaccharides from Tussilago farfara L.also induced genoprotective properties against the chemo side effects.

Taken altogether, coltsfoot may be considered a remedy for the protection of bone marrow cells integrity against the onset of leukemia, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective Effect of Polysaccharides from Tussilago farfara L. on Bone Marrow Cells and Small Intestinal Epithelium Under Conditions of Polychemotherapy Evaluated by DNA Comet Assay by Safonova EA1, Lopatina KA2, Vychuzhanina AV2, Mashanova VA2, Razina TG2, Borovskaya TG2, Zueva EP2, Gur'ev AM3, Belousov MV. (PubMed)

Herbal Ashwagandha Inhibits the Risk of Chronic Generalized Periodontitis

By Kyle J. Norton

Gingivitis is a common and mild form of periodontal disease caused by inflammation of the gingiva, leading to symptoms of irritation, redness, and swelling of the gum that lines the base of the teeth.

Gingivitis dental plaques formed around the base of the teeth are sticky biofilm of bacteria associated with the interaction of the food intake and bacteria in the mouth. Over time, if untreated, the condition can lead to periodontitis and advanced periodontitis.

At this early stage, the bone and connective tissue that hold the teeth in place are not yet affected. The problems can be reversed by more frequent and proper brushing and flossing.

Most common cause of gingivitis is poor hygiene. Epidemiologically, risk factors induce the onset of gingivitis are smoking or chewing tobacco. diabetes and long-term use of certain medication including oral contraceptives, steroids, anticonvulsants, calcium channel blockers.

Some people under treatment of chemotherapy may also experience symptoms of gingivitis.

Periodontitis is a severe stage of gingivitis that damages the soft tissue and destroys the bone that supports your teeth, leading to teeth loosen or tooth loss.

Periodontitis can be classified into
* Chronic periodontitis is caused by plaque buildup and involves slow deterioration of the gums and bone and loss of teeth if not treated. The condition is a common condition that affects mostly adults.

* Aggressive periodontitis found mostly in childhood or early adulthood. The condition is rare that causes rapid progression of bone and tooth loss if untreated.
* Necrotizing periodontal disease is a severe infection that causes the death of gum tissue, tooth ligaments and supporting bone.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean. The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for the treatment of oral health, researchers examined the effects of WA on periodontitis.

In vitro, Herbal ashwagandha possessed marked anti-inflammatory effect against denaturation of proteins associated with the loss of the quaternary structure, tertiary structure, and secondary structure, probably through the herbal alkaloid and withanolide contents.

Furthermore, herbal ashwagandha also induced adaptogenic, immunomodulating, antibacterial, anti-inflammatory against on the onset of periodontitis.

The enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase produced by the host are the increased by the administration of WA against bacterial-induced inflammatory periodontitis.

Moreover, Ashwagandha supplementation also showed to process activity to act as an adjunct to scaling and root planing(SRP) in chronic periodontitis(CP) patients by inhibiting oxidative stress (OS) and increased levels of acute-phase proteins associated with gingival inflammation and periodontitis.

Based on the findings, researchers said, "Changes in peripheral blood cellular and molecular components can be seen in patients with periodontitis, as periodontitis includes inflammatory changes of the periodontal tissues".

Taken altogether, Ashwagandha may be considered a functional herb for the prevention and an adjunct therapy combined with the primary medicine for the treatment of periodontitis, pending to the result of larger sample size and multicenter study



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You  How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of Ashwagandha on Salivary Antioxidant and Serum c Reactive Protein in Chronic Generalized Periodontitis by NIH
(2) Periodontitis by Mayo Clinic

Tuesday, 24 September 2019

Healthy Food Turmeric Improves the Function of Peripheral Nerves, Neuropathy in Patients with Dejerine-Sottas Disease

By Kyle J. Norton

Dejerine-Sottas disease is an inherited neurological disorder that causes the enlarged or thickened peripheral nerves, leading to muscle weakness.

Most cases of Dejerine-Sottas disease begin suddenly, in population between 10 and 30 years of age.

Beside muscle weakness, patients with the disease also experience symptoms of pain, weakness, numbness, and a tingling, prickling or burning sensation in the legs. 

Conventionally, treatment of Dejerine-Sottas disease is focusing on reducing symptoms and slowing the progression of the disease and improving quality of life.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

With an aim to find a potential compound for the treatment of Charcot-Marie-Tooth disease type 1B caused by mutations in myelin protein zero, researchers examined the effect of turmeric on an animal model.

The study included R98C mice, an authentic model induced the early onset Charcot-Marie-Tooth disease type 1B, in the developing neuropathy.

According to the tested assays, R98C mutant mice were treated with curcumin dissolved in sesame oil or phosphatidylcholine curcumin, starting at 4 days of age showed an increased numbers of large-diameter axons in their sciatic nerve.

The aforementioned compound also demonstrated an increased compound muscle action potential amplitudes and the innervation of neuromuscular junctions without improving the nerve conduction velocity, myelin thickness, G-ratios or myelin period in transmitting electrical impulses. 

Additionally, the protein associated with the onset of neurodegenerative disease X-box binding protein (XBP1) splicing was also decreased by the treatment of curcumin dissolved in sesame oil or phosphatidylcholine curcumin.

Based on the findings, researchers wrote, "these data demonstrate that treatment with curcumin dissolved in sesame oil or phosphatidylcholine curcumin improves the peripheral neuropathy of R98C mice by alleviating endoplasmic reticulum stress, by reducing the activation of unfolded protein response and by promoting Schwann cell differentiation".

In other words, curcumin protects the nerve cells against the onset of peripheral neuropathy by reducing the nerves damage that carries messages to and from the brain and spinal cord from and to the rest of the body.

Taken altogether, turmeric may be considered supplements for the treatment of neuropathy in patients with Dejerine-Sottas disease, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice by Patzkó A1, Bai Y, Saporta MA, Katona I, Wu X, Vizzuso D, Feltri ML, Wang S, Dillon LM, Kamholz J, Kirschner D, Sarkar FH, Wrabetz L, Shy ME. (PubMed)

Bromelain Inhibits the Onset of Acute Diarrhea in Vivo

By Kyle J. Norton

Diarrhea is an acute condition of loose, watery stools (bowel movements). In other words, if you have loose stools three or more times in one day, you are considered to have diarrhea.

Most cases of diarrhea are acute that last for a few days. However, chronic diarrhea that lasts for a long period of time is an indication of other medical conditions, including irritable bowel disorder, or inflammatory bowel disease.

Accompanied by loose and watery stool, patients with chronic diarrhea also experience abdominal cramps and pain, fever, blood and mucus in the stool, bloating, nausea and the urge of a bowel movement.

Most common causes of diarrhea are an infection caused by bacterias and virus. Some medications such as antibiotics also have been found to induce acute diarrhea.

The condition in some cases can also be induced by lactose intolerance, fructose, artificial sweeteners and other digestive disorder such as Crohn's disease, ulcerative colitis, celiac disease.

Acute diarrhea can be treated successfully if the cause is found. Untreated diarrhea has been found to cause complications of dehydration, particularly in children and a weakened the immune system in older adults

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and for the treatment of pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

On finding a natural compound for the treatment of diarrhea, researchers examined the effects of bromelain on K88 positive enterotoxigenic Escherichia coli (K88+ ETEC), an important cause of diarrhea in young piglets.

The study included bromelain (0, 12.5, or 125 mg) orally administered to just weaned piglets for 10 days following by the commencement of bromelain treatment, piglets were challenged with K88+ ETEC (5 x 10(10) K88ac:0149) for seven days.

Injection of 12.5 or 125 mg showed a significant effect in reducing the incidence of K88+ ETEC diarrhea and protected piglets from a life-threatening disease.

Both doses of bromelain treated pigs also had significantly increased weight gain compared to untreated pigs.

However, bromelain only temporarily inhibited K88+ ETEC receptor activity observed by the receptor activity being regenerated 30 hours following treatment, consistent with the regeneration of new enterocytes.

In other words, both doses of bromelain can only temporarily inactivate ETEC receptors in vivo and protect against ETEC induced diarrhea.

These results strongly suggested that bromelain treatment prevented the attachment of K88+ ETEC to piglet small intestines that inhibits the risk of K88+ ETEC pathogenesis.

Based on the finding, Dr. Chandler DS, the lead scientist wrote, "Bromelain may, therefore, be an effective prophylaxis against ETEC infection".

Taken altogether, bromelain used alone or combined with conventional medicine may be considered a remedy for the prevention and treatment of diarrhea, pending to the confirmation of the larger sample size and multicenter human study.

Intake of bromelain in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Bromelain protects piglets from diarrhoea caused by oral challenge with K88 positive enterotoxigenic Escherichia coli by Chandler DS1, Mynott TL. (PubMed)