Beet, The Root Veggie That Inhibits Bladder Cancer Cells

By Kyle J. Norton

Intake of function food beet root regularly not only lowers the early occurrence but also provides a natural treatment of bladder cancer without inducing adverse effects.

Bladder cancer is a medical condition characterized by irregular cell growth and multiplied disorderly and uncontrollably in bladder tissues.

According to statistic, men are 4 times like to get bladder cancer in compared to women. The condition is the 9th common cancer worldwide.

Every-year, approximately 400, 000 new cases are diagnosed. The 5 years of survival rate included all stage of bladder cancer is about 77% in compared to 70% and 65% of 10 years and 15 years respectively.

The survival rate of early diagnosed of bladder cancer is at 98%.

The causes of bladder are unknown. However, some researchers suggested that smoking and tobacco used is one major cause of bladder cancer.

 Long term exposure to chemicals and irritation of the lining of bladder due to infection are associated to risk factors of the disease.

Most common symptoms of bladder cancer are blood in urine accompanied with painful urination,... and pelvic pain. You should check with your doctor right the way, you experience some of these symptoms.

Dr. Martin C. S. Wong the lead scientist at the joint study conducted by the The Chinese University of Hong Kong and other institutes said, "Many European countries experienced incidence rise. A substantial mortality reduction was observed in most countries, yet increases in mortality rates were observed in the Philippines and Iceland. These findings identified countries where more preventive actions are required"(4).

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to University of Urbino 'Carlo Bo', betaxanthins and betacyanins, isolated from beet root exerted a significant anti cancer effects in testing bladder cancer cell lines, through expression of antioxidant and pro apoptotic activities.

The anti cancer property of beet root also displayed a strong anti angiogenesis by blocking the cancer cell in established new blood vessel signalling.


When used combination with Vitexin-2-O-xyloside, an apigenin flavone glucoside, betaxanthins and betacyanins also exerted a strong antiproliferative activity in bladder cancer cell lines, intrinsically and extrinsically in expression of apoptosis.

The study also indicated that these combination when used conjunction in the conventional chemotherapy not only enhance the effectiveness of treatment in bladder cancer but also overcome the adverse effect of toxicity and multidrug resistance of cancer cells.

Furthermore, in other study conducted by the same university, Betacyanins (BC) purified from beetroot (Beta vulgaris var. rubra L.) tested,alone or in combination with vitexin-2-O-xyloside (XVX) also isolated from the same vegetable enhanced the ability to reduce the proliferation rate in T24 bladder cancer cells, synergistically.by inhibition of protein of gene in promoted cell survival and enhanced cancer apoptosis.

Taking together, a diet enriched with these bioactive molecules of beet root could be used as function food in prevention and treatment of human bladder cancer.

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Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)
(2) Betacyanins enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells by Scarpa ES1, Emanuelli M2, Frati A1, Pozzi V2, Antonini E1, Diamantini G1, Di Ruscio G3, Sartini D3, Armeni T3, Palma F1, Ninfali P1.(PubMed)
(3) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)
(4) The global epidemiology of bladder cancer: a joinpoint regression analysis of its incidence and mortality trends and projectio by Martin C. S. Wong,1,2 Franklin D. H. Fung,1 Colette Leung,1 Wilson W. L. Cheung,1William B. Goggins,3 and C. F. Ng(PMC)

Believe It or Not, Fennel May Alleviate Daily Stress Automatically and Naturally, Scientists Discover

Kyle J. Norton


Fennel may have a potential and positive effect in reduced negative stress impact on daily living, some scientists suggested.

Stress in a natural response of our brain against any kinds of threat and demand. People responded to stress differently, some can cope with stress that no one else can.

However, if stress is over whelming, caused over productions of certain hormones that can induce strong implications in interfered one's daily activity.

Prolonged stress is found to exert physically, emotionally and mentally negative expression in various aspects, including sleep disturbance, digestive disorders,....

Some researchers suggested that people with chronic stress not only increases risk of heart attack and stroke, speeds up the aging process but also are susceptible to risk of metal conditions, such as anxiety, depression, and other mental health problems.

If you experience some abnormal cognitive, emotional, physical,....... and behavior symptoms, you may be in the early stage of chronic stress. Please check with your health service providers.

Causes of stress can be external and internal,

* External stress includes:  difficulty in relationship, at work stress, financial problem, loss of love one,...... and financial problems.

* Internal stress includes: pessimism, rigid thinking, lack of flexibility,........and negative thinking.

Chronic stress if untreated can lead to development of some serious ailments, including mental disorders, abnormal endocrine functions, cardiovascular disease,.......... and respiratory problems.

Some researchers suggested that people with untreated chronic stress also are likely to increase risk of infections, digestive problems and muscular pains, particularly headaches and migraine attack.

Furthermore, society and environment also have significant impacts on stress conditions.

According to the widely validated Holmes and Rahe Stress Scale, the top ten stressful life events for adults, include
Death of a spouse
Divorce
Marriage separation
Imprisonment
Death of a close family member
Injury or illness
Marriage
Job loss
Marriage reconciliation
Retirement

Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean.

The herb or food also is used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...

Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.



In the study to evaluate the anti-stress and memory-enhancing properties of F. vulgare extract in experimentally stress rats at doses of 50, 100 and 200 mg/kg body weight administered orally with an orogastric tube, researchers found that rats treated with all doses exert significant effect in reduced stress implication linearly, observed by Urinary levels of vanillylmandelic acid (VMA) assay in 24 hours.


Further analysis of fennel rat treated group  with additional injection of ascorbic acid also found that the secretion of urinary ascorbic acid levels increased from 65.74 to 78.59, 108.41 and 125.82 μg/kg within the same period on doses of 50, 100 and 200 mg/kg body weight respectively in compared to untreated control group.

These results indicated that fennel has a stronger impact in reduced chronic stress connotation in compared to both ascorbic acid and control groups.

Moreover, treated group also displayed a reduced expression of lipid peroxidation in both rat liver and brain homogenates catalyzed by the stress in induction of ROS production and reduction of natural antioxidant defense in compared to rat group treated with ascorbic acid.

Dr. S Koppula,, the lead author, after taking into account of other con founders said, "The (Fennel) extract also exhibited potent antioxidant effect by inhibition of lipid peroxidation in both rat liver and brain homogenates to a greater extent than the standard antioxidant, ascorbic acid".


Additionally, in the review literature of number of such drugs mostly in the form of their extracts (holistic approach) or in some,of  active principles isolated from them for their antistress activity by a number of tests, researchers found that
* Fennel may have a strong effect in reduced stress in tested mice through observation of swimming endurance and hexobarbitone sleeping time in association to stress in induction of anxiety.

* Fennel inhibits the production of level stress hormone corticosterone produced in the cortex of the adrenal gland.

* Fennel increases production antioxidant and enhanced the antioxidant defense of host such as Superoxide Dismutase (SOD) and sorbitol dehydrogenase (SDH), in inhibited over expression of ROS in initiated chain reaction caused by chronic stress.

* Fennel inhibits levels of MAO in association to alternation of mood and mental conditions.

Finally, application of fennel also reduced tension of central nervous system in response to stress impact, thus reducing neurotransmitter levels in stimulated production of stress hormones in facilitated ROS production, depression, anxiety,.......


The above illustration were supported by the application of fennel oil in exerted significant anti psychiatric disorders caused by chronic stress such as depressive and anxiety in tested mice respectively treated with water, fluoxetine (0.3 mg/kg) and fennel oil (0.5 ml/day) conducted by the Aga Khan University

Repeated administration of fennel oil for 3 weeks demonstarted significant antidepressant- and anxiolytic-like effects, observed by struggling time in forced swim test (FST) and time spent in open arm in elevated plus maze (EPM) in comparable to fluoxetine treatment group.

Interestingly, rats treated group also exhibited a high levels of antioxidant in inhibited ROS in facilitated production of free radicals through lipid peroxidation.

Taken together, fennel with abundant phytochemicals may be considered as a functional food in reduced stress implication in initiation of related diseases.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Foeniculum vulgare Mill (Umbelliferae) Attenuates Stress and Improves Memory in Wister Rats by S Koppula, H Kumar(Tropical Journal of Pharmaceutical Research)
(2) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PubMed)
(3) Untreated Stress Can Lead To Serious Problems(Aarogya)
(4) Stress Symptoms, Signs, and Causes(Help guide)

Chamomile Enhances Immune System Integrity and Immune Cells Viability

By Kyle J. Norton, Master of Nutrition


Herbalism or phytotherapy a traditional medicine used botany and plants as medical treatment, linking health benefits in prevention, management and treatment of diseases has drawn much interests in today respectable scientists.

But herbal qualities, because geographic differences, time of grown,..... and harvest, are still raised some concerns of conventional researchers.

How many conscientious scientists do believe that some days phytotherapy will replace conventional single ingredient medicine for treatment of diseases without inducing serious side effects.

Would the big pharmaceutical companies whose bottom line is nothing but profits and more profits allowed that to happen?

Immunomodulatory effect is a function that stimulates T-cell proliferation, natural killer (NK) cell cytotoxicity, production of cytokines by human peripheral blood mononuclear cells (PBMCcs),.... and nitric oxide (NO) production.

In other words, improving immune function of modulation of gene or neurohormonal system may exert a strong efficacy in protected our body against harmful agents, including micro organisms,......and immunotoxins.

Immune dysfunction can be expressed in several different ways, depending to whether the immune system is overactive or underactive.

In long term overactive immune function, patient may be experience some symptoms of chronic inflammation caused by over production of pro inflammatory cytokines. Diseases associated to these syndromes include, asthma, rheumatoid arthritis (RA), type 1 diabetes...... and Inflammatory bowel disease

Long term of underactive immune system can reduced immune function in fighting against various pathogens or toxins, leading to development of diseases. Diseases associated underactive immune function include Human immunodeficiency virus / acquired immune deficiency syndrome (HIV/AIDS),....

The causes of immune dysfunction, in joint investigation of " Immune Dysfunction as a Cause and Consequence of Malnutrition" lead by the Queen Mary University of London, suggested "Malnutrition results from disordered nutrient assimilation but is also characterized by recurrent infections and chronic inflammation, implying an underlying immune defect." and " Defects emerge before birth via modifications in the immunoepigenome of malnourished parents"(3).

Patients with chronic immune dysfunction are associated to increase risk of morbidity and mortality(4)(5).

Chamomile is also known as camomile, common name of many species daisy-like plants, belongings to the family Asteraceae, native of the Old World.

The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.

Chamomile (Matricaria chamomilla), in recent study conducted by some institutions, restored the resistance against lethal infection with the predominately granulocyte-dependant Candida albicans in immunosuppressed mice.

Administration of the chamomile extract in five doses enhanced the total white blood cells count (up to 1.2 × 10(4) cells/mm(3)) and increased significantly bone marrow cellularity.

Some researchers suggested, "Changes in bone marrow cellularity can be an indicator of systemic toxicity and, therefore, bone marrow should be included in the battery of tissues examined for enhanced histopathology of the immune system"(6).

In other words, increased numbers of bone marrow cellularity has a strong effect in enhanced immune function.

Heteropolysaccharides found in Matricaria chamomilla L. also showed to normalize the developing of the immune response upon air cooling as a result of initiated immunostimulating properties of enlargement of red blood cells and activization of immunoregulation cells.

Dr. Ghonime M, the lead author, said, "immunomodulatory activity,.....Chamomile extracts may have therapeutical implications in prophylactic treatment of opportunistic infections and as supportive treatment in oncogenic cases".

There is no doubt that chamomile and its chemical ingredients have expressed a strong immunomodulatory activity in protection of our body against various diseases, but intake of large quantity should be taken with care to avoid toxicity.

However, further data collection with larger example size and multi centers performed on human consumption over a long term and during the course of the disease will be necessary to complete the picture of chamomile immunomodulatory possibilities.

Additionally, while addressing the possible advantages of chamomile's immunomodutary activities, researchers must also take into account of potential, risk such as, quality controls, dosages and dosage induced adverse effect of acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Evaluation of immunomodulatory effect of three herbal plants growing in Egypt by Ghonime M1, Eldomany R, Abdelaziz A, Soliman H.(PubMed)
(2) [The immunomodulating activity of the heteropolysaccharides from German chamomile(Matricaria chamomilla) during air and immersion cooling].[Article in Russian] by Uteshev BS1, Laskova IL, Afanas'ev VA.(PubMed)
(3) Immune Dysfunction as a Cause and Consequence of Malnutrition by Claire D. Bourke,1,⁎ James A. Berkley,2,3 and Andrew J. Prendergast(PMC)
(4) Extrahepatic morbidity and mortality of chronic hepatitis C by Negro F1, Forton D2, Craxì A3, Sulkowski MS4, Feld JJ5, Manns MP(PubMed)
(5) [Morbidity and mortality in HIV infection].[Article in German] by Stöckle M1, Elzi L, Rockstroh JK, Battegay M(PubMed)
(6) Enhanced Histopathology of the Bone Marrow by SUSAN A. ELMORE, the Society of Toxicologic Pathology

Holistically, The Easy Ways to Prevent and Treatment of Benign Prostatic Hyperplasia(BPH)

Kyle J. Norton

Benign prostatic hyperplasia(BPH) is a condition of increased numbers of cell of prostate tissues, causing partial, or sometimes virtually complete obstruction of the urinary tract.

According to statistic, BPH commonly starts at age of 30 and symptoms usually can not be realized until age of 50.

More than half of men between age of 60-70 are experience symptoms of BPH and only 10% are required treatment.

Suggestion of BPH is associated to nutritional status and eating habits. According to the study, 30 male patients with clinically confirmed and treated disease of the prostatic gland, including 15 men (aged 51-75 years) with BPH and 15 men (aged 51-73 years) with PC, improper nutritional status leading to incorrect nutritional habits and failing to improve their health, may be the cause of the development of some diet-dependent diseases, such as BPH and prostate cancer(a).

A proper diet with vegetable, fruit containing zinc may reduce the risk of the disease from initiation(b)(c).

Epidemiological studies, indicated intake of vegetables and fruits accompanied with healthy life style may be associated in prevented risk and treatment of enlarged prostate(d)(e)(f)in inhibited over production of prostate cells though antioxidant activity (g)(h).

Medication used for treatment of enlarged prostate may be effective in the early ad mild stage of the disease but with significant side effect, such as
* Alpha blockers used to relax bladder muscle and fiber in the prostate may cause adverse effects of dizziness and a harmless condition and semen reversed flowing.

* 5-alpha reductase inhibitors used to control hormone implication of enlarge prostate may induce side effects of infertility caused by retrograde ejaculation.

* Tadalafil (Cialis) intake may cause symptoms of redness or warmth in your face, neck, chest,.... and muscle pain, back pain.

If you are taking these kind of medicine, please make sure you discuss the side effects with your doctor.

In many instances, if the medicine do not work or symptoms become too severe, surgery may be only option, including transurethral resection of the prostate (TURP), transurethral incision of the prostate (TUIP),.....or laser theory.

.
If you choose to treat your enlarged prostate holistically, you may want to add one or two of below to your diet(pumpkin seeds are the best). Please note that these foods may take one to 2 months to exert their efficacy, accompanied with change of diet such as increased intake of vegetables and fruits and lifestyle.

Intake of these foods regularly will prevent onset and treatment of enlarged prostate.

Top 5 Foods to prevent and treatment of Benign prostatic hyperplasia(BPH) naturally
1. Green tea
Green tea containing more amount of antioxidants than any drinks or food with the same volume, is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China.

Green tea is a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years.

Because of their health benefits, they have been cultivated for commercial purposes all over the world.

In the examine the levels and activity of androgen hormones in associated to the risk of BPH, researchers indicated that application of green tea catechin, (-)epigallocatechin-3-gallate, modulated the expression androgenic activity in reduced progression of benign prostatic hyperplasia.

These result suggested that EGCG may be useful for the treatment of various hormone-related abnormalities, inckuding benign prostatic hyperplasia(29)(32)

5 alpha-reductase activity long has suspected to a significant impact in induction of early onset of benign prostatic hyperplasia,

According to the study conducted by the Ben May Institute for Cancer Research, and The Tang Center for Herbal Medicine Research, administration of green tea catechin (-)-epigallocatechin gallate (EGCG) exerts a strong effect in replaced the gallate ester with long-chain fatty acids in acting as a potent 5 alpha-reductase inhibitors(30).

The study by the Oregon State University, also indicated that the combination of soy and tea attenuated prostate malignancy by decreasing prostate hyperplasia in male noble rats implanted with estradiol and testosterone(31)


2. Coffee
Coffee made from the roasted seeds of the genus Coffee, belongings to the family Rubiaceae native to southern Arabia.

According to Dr. Morrison AS. coffee drinking was inversely but only weakly related to prostatic hypertrophy(BPH) in 910 residents of Rhode Island who had a partial or total prostatectomybetween the years 1985-1987(33).

In a study of a total of 1369 patients younger than 75 years old surgically treated for BPH and 1451 controls younger than 75 years of age, the prevalence of BPH was insignificantly among coffee drinkers(34)(35)

However, according to the study by the Univ Estadual Paulista (UNESP) in the rat prostate gland, chronic caffeine intake from puberty may increase androgenic signalling and cell proliferation in initiated development of benign prostatic hyperplasia(36).

3. Pumpkin seeds
Pumpkin seed(PS) or pepita, an edible seed of a pumpkin with flat, dark green color is the genus Cucurbita and belonging to the family Cucurbitaceae.

The origin of pumpkins is unknown, although many people believe that pumpkins are originated in North America.

According the study of 20 male Wistar rats, conducted by the Michael Okpara University of Agriculture, injection of pumpkin seeds inhibited the induction of BPH and through increasing the testosterone:estradiol ratio(37).

In a randomized, double-blind, placebo-controlled trial in over 12 months on 47 benign prostatic hyperplasia patients with average age of 53.3 years and international prostate symptom score over 8, researchers showed that PS demonstrated a positive effect in treatments of benign prostatic hyperplasia(38).

Other study also suggested that oral administration of pumpkin seed oil inhibits testosterone-induced hyperplasia of the prostate(39).

4. Coconut oil
Coconut palm tree is a genus cocos, belongings to the family Arecaceae, native to the tropic and subtropic area.

According to chemical differentiation, coconut oil may reduce total cholesterol, triglycerides, phospholipids, LDL, and VLDL cholesterol levels and increased HDL cholesterol in serum, etc through numbers of phytochemicals.(40).

Coconut oil reduced the increase of both prostate weight (PW) and body weight (BW) ratio, markers in testosterone-induced PH in rats(41).

5. Fish oil
Fish oil, rich in long-chain polyunsaturated essential fatty acids of the omega-3 group may have a potential effect in reduced BPH risk.

According to the study by the University of California at Davis, gamma-linolenic acid (GLA) from fish oil inhibited 80% of gamDHT-enhanced activity of 5 alpha-reductase(42).

Other, in the study of the serum samples of 24 BPH and 19 PC patients, and from 21 age-matched normal male subjects, scientists found that the omega-3 PUFAs level was significantly decreased in patient with BPH(43).

However, in the study to compare the levels of n-3 polyunsaturated fatty acids (PUFAs) in leukocytes and prostate tissue in men with prostate cancer or benign prostatic hyperplasia (BPH), scientists found that long-chain polyunsaturated essential fatty acids intake is not associated in reduced risk of BPH(44).

Taking together, certain foods have been found effectively in reduced risk and treatments of Benign prostatic hyperplasia(BPH). But large sample and multi centers studies are necessary for reconfirm the viability.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.References
(a) Nutritional status and nutritional habits of men with benign prostatic hyperplasia or prostate cancer - preliminary investigation by Goluch-Koniuszy Z, Rygielska M, Nowacka I.(PubMed)
(b) Diet and benign prostatic hyperplasia: a study in Greece by Lagiou P1, Wuu J, Trichopoulou A, Hsieh CC, Adami HO, Trichopoulos D.(PubMed)
(c) Associations of obesity, physical activity and diet with benign prostatic hyperplasia and lower urinary tract symptoms by Raheem OA1, Parsons JK.(PubMed)
(d) Nutrition and benign prostatic hyperplasia by Espinosa G.(PubMed)
(e) Dietary patterns and prostatic diseases by Sebastiano C1, Vincenzo F, Tommaso C, Giuseppe S, Marco R, Ivana C, Giorgio R, Massimo M, Giuseppe M.(PubMed)
(f) Fruit and vegetable consumption, intake of micronutrients, and benign prostatic hyperplasia in US men by Rohrmann S1, Giovannucci E, Willett WC, Platz EA.(PubMed)
(g) Evaluation of oxidative stress and DNA damage in benign prostatic hyperplasia patients and comparison with controls by Ahmad M1, Suhail N, Mansoor T, Banu N, Ahmad S(PubMed).
(h) Oxidative stress and antioxidant status in non-metastatic prostate cancer and benign prostatic hyperplasia by Aydin A1, Arsova-Sarafinovska Z, Sayal A, Eken A, Erdem O, Erten K, Ozgök Y, Dimovski A.(PubMed)
(29) The medicinal action of androgens and green tea epigallocatechin gallate by Liao S.(PubMed)
(30) Structure-activity relationships for inhibition of human 5alpha-reductases by polyphenols by Hiipakka RA1, Zhang HZ, Dai W, Dai Q, Liao S.(PubMed)
(31) Dietary soy and tea mitigate chronic inflammation and prostate cancer via NFκB pathway in the Noble rat model by Hsu A1, Bruno RS, Löhr CV, Taylor AW, Dashwood RH, Bray TM, Ho E.(PubMed)
(32) The medicinal action of androgens and green tea epigallocatechin gallate by Liao S.(PubMed)
(33) Risk factors for surgery for prostatic hypertrophy by Morrison AS.(PubMed)
(34) Food groups and risk of benign prostatic hyperplasia. by Bravi F1, Bosetti C, Dal Maso L, Talamini R, Montella M, Negri E, Ramazzotti V, Franceschi S, La Vecchia C.(PubMed)
(35) Benign prostatic hyperplasia: the opposite effects of alcohol and coffee intake by Gass R.(PubMed)
(36) Chronic caffeine intake increases androgenic stimuli, epithelial cell proliferation and hyperplasia in rat ventral prostate by Sarobo C1, Lacorte LM, Martins M, Rinaldi JC, Moroz A, Scarano WR, Delella FK, Felisbino SL.(PubMed)
(37) Inhibition of the experimental induction of benign prostatic hyperplasia: a possible role for fluted pumpkin (Telfairia occidentalis Hook f.) seeds by Ejike CE1, Ezeanyika LU.(PubMed)
(38) Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia by Hong H1, Kim CS, Maeng S.(PubMed)
(39) Inhibition of testosterone-induced hyperplasia of the prostate of sprague-dawley rats by pumpkin seed oil by Gossell-Williams M1, Davis A, O'Connor N.(PubMed)
(40) Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation. Nevin KG. Rajamohan T. Clinical Biochemistry. 37(9):830-5, 2004 Sep. [Comparative Study. Journal Article] UI: 15329324 Authors Full Name Nevin, K G. Rajamohan, T.
(41) Effects of coconut oil on testosterone-induced prostatic hyperplasia in Sprague-Dawley rats. by de Lourdes Arruzazabala M1, Molina V, Más R, Carbajal D, Marrero D, González V, Rodríguez E.(PubMed)
(42) 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids by Pham H1, Ziboh VA.(PubMed)
(43) Comparison of fatty acid profiles in the serum of patients with prostate cancer and benign prostatic hyperplasia by Yang YJ1, Lee SH, Hong SJ, Chung BC.(PubMed)
(44) Prostate tissue and leukocyte levels of n-3 polyunsaturated fatty acids in men with benign prostate hyperplasia or prostate cancer by Christensen JH1, Fabrin K, Borup K, Barber N, Poulsen J.(PubMed)

The Phytochemicals That Devour Kidney Cancer Cells

Kyle J. Norton


Lentils' (plant sources') lectin may be considered as biomarkers for detection of the early stage of varies types of cancer and treatment of renal cancer, some scientists suggested.

Lentil, a type of pulse and tiny legume that can be cooked quickly and rich in protein and fiber is a bushy annual plant of genus Lens to the Fabaceae family, native to Middle East.

Kidney Cancer is a medical condition characterized by irregular cells growth in the tissue of kidneys.
At the later stage, the cancerous cells may traval a distance way to infect other organs' tissues.
For example, if kidney cancer spread to the lung is called kidney cancer with lung metastases.

At the very early stage of kidney, cancerous tumours that are localized in surface of the kidneys.
The  most common type of kidney cancer is renal cell cancer.

The kidney is of 3 main detoxified organs with main function of filtering water and waste from your blood.

The causes of kidney is unknown, but some researcher suggested that genetic mutation, cigarette smoking, obese, family history,..... and exposed to chemicals, such as asbestos and benzene are all associated to increased risk of kidney cancer.

The cancer is only infected approximately 2% of general population and screening test is only designated for kidney cancer in people who are in higher risk of the disease.

In UK, The survival rate of early diagnosis of early stage of kidney cancer is very high with five-year survival rates for renal cancer of 70-94% for localized tumors

According to statistics reported by Dr. Lewis G, the lead author, " Kidney cancers account for 2-3% of all adult malignancies in the UK. Men are predominantly affected by renal cancer with an average age at diagnosis of 64 years. Renal (or clear) cell carcinoma (RCC) accounts for 90% of kidney cancers"(4) and "RCC should be suspected in the presence of localising symptoms such as flank pain, a loin mass or haematuria; constitutional upset including weight loss, pyrexia and/or night sweats; or with unexplained laboratory tests"(4).

Imaging tests such as computed tomography (CT) or magnetic resonance imaging (MRI), are the best to spot cancer in patients who are at high risk and susceptible of kidney cancer.

According to the investigation of plant lectin effect in risk of cancers, by resisting digestion, lectins after intake maintained full biological activity in binding to the cancer cell remembrances or. and receptors to induce cytotoxicity, thus reducing cancer cell proliferation and inhibiting tumor growth.

 lectins can also incorporate into cancer cell as an antigen to cause agglutination and/or aggregation in induction of cytolysis and inhibite expression of polyamines, small organic cations that are essential for cancer cells to growth.

Furthermore, plant lectins altered the production of various interleukins that are essential importance for the function of both innate and adaptive immunity by activated certain protein kinases in regulating signal transduction pathways in control cancer cells process in induction of tumor progression.

Additionally, lectins can also bind to cancer cell mutated ribosomes, a cell structure that makes protein and inhibit protein synthesis, thus disrupting the critical cellular processes necessary for sustained cancer cell growth and modified the cancer cell phase 1 division and  G2/M phase cell cycle arrest.


Interestingly, injection of lectins also inhibited telomerase expression in cancer cell activity in maintaining tumor progression and angiogenesis in stimulated production of new blood vessel to provide nutrients and oxygen to cancer cells proliferation and tumor expansion.

In clear-cell renal cell carcinoma (ccRCC), Galectin-9 (Gal-9), an animal lectin injection exerted a significant effect in inhibited cancer cell proliferation through binding to β-galactoside which is important to provide energy to tumor survival.

Further investigation of the expression of Gal-9 in a total of in 196 patients with ccRCC who underwent nephrectomy, with 48/196 patients died and 61/196 patients suffered recurrence to assess the prognostic value of Gal-9, suggested that Gal-9 expression not only associates positively with tumor size, but also induces a direct impact in the relative survival ratio, used to predict overall survival (OS) and recurrence-free survival (RFS) of patients.

Indeed, high levels of Gal-9 was found to associate correlately to poor survival and early recurrence and the expression of lectin also can be considered as a biomaker in diagnosed clear-cell renal cell carcinoma (ccRCC) in early stage and lower of grade of tumor, node, and metastasis in patients who are at higher risk of the kidney cancer developing.

The finding evidences suggested that lectins from all sources may be considered as a therapeutic substances and biomarkers for treatment and monitoring the progression of kidney cancer.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Lectin reactivity of alpha-fetoprotein in a case of renal cell carcinoma by Taketa K1, Ichikawa E, Sakuda H, Iwamasa T, Hayakawa M, Taga H, Hirai H.(PubMed)
(2) Lectins as bioactive plant proteins: a potential in cancer treatment by De Mejía EG1, Prisecaru VI.(PubMed)
(3) Galectin-9 predicts postoperative recurrence and survival of patients with clear-cell renal cell carcinoma by Fu H1, Liu Y, Xu L, Liu W, Fu Q, Liu H, Zhang W, Xu J.(PubMed)
(4) Early diagnosis improves survival in kidney cancer by Lewis G1, Maxwell AP(PubMed)

A Herbal Gel That Is Better Than Non-Steroidal Anti-Inflammatory Medications in Healing Ecchymosis With No Side Effects

Arnica may have a potential and therapeutic effect in reduced expression of Ecchymosis, through its anti inflammatory activities, some scientists suggested.

The results of these efficacy were confirmed by some studies conducted by numbers of respectable institutes, including University of Miami Miller School of Medicine and University of South Florida.

Ecchymosis is a condition of discoloration of the skin as a result of bleeding underneath. In most cases it is caused by bruising.

Some people may be mistaken a hematoma as ecchyymosis.

Normally, ecchyymosis is any bruising less than 1 cm and ecchymosis is considered as a hematoma if the bruising of skin is larger than 1 cm.

In other word, hematoma contains blood clots which can be felt when touched, and often exerting symptoms of pain and tenderness, in compared to ecchymosis.

The most common symptoms of ecchymosis is the progression of colors, usually follow this order: red or purple, black or blue, brown and yellow.

Truly, ecchymosis mostly appears on your arms and legs since they’re most likely to be injured. However, bruising can also happen to anywhere such as strain or sprain a bone, particularly in wrist or ankle.

Long term intake of certain medication such as blood thinners, such as aspirin or warfarin, antibiotics,.... and corticosteroids also increases risk of bleeding and bruising.

Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, antive to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is process of repairing after damage of skin, tissues, organs, etc.


The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivative.


In order to confirm the effect of herbal Arnice activity in treatment of ecchymosis in patients who under went rhinoplasty, the most common facial plastic surgical procedure, researchers at the joint study lead by the University of South Florida independently conducted a review of literature in databases (PubMed, SCOPUS, Embase, Web of Science, and the Cochrane database) from inception to September 2016, included studies that compared postoperative care methods (intervention groups) with no treatment (control group).

According to the final searching of 11 trials satisfied the criteria and guideline with a total of 627 patients, application of topical Arnica showed a significant effect in reduced eyelid ecchymosis during the first 7 days postoperative statistically in compared to the control group.

However, eyelid ecchymosis during the first 24 h postoperatively were statistically decreased in the cold compression group in compared to the control group.

Patients' questionnaires returned also expressed a strong satisfaction in the tapping application group than in the control group.

Also, the ratio of patient satisfaction was statistically higher in the tapping and Arnica application group than in the control group.

Additionally, the analysis also found that surgeons had a significant tendency to decrease intranasal packing in remove pain from the surgery area as the placement was found to associate with more adverse effects in terms of postoperative ecchymosis compared to non-packing.

Further differentiation to confirm the effectiveness of the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) in reducing postoperative ecchymosis in a select population of healthy volunteers after oculofacial surgery, researchers conducted a review examined the postoperative course of healthy volunteers using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012 using medical records review.

A total of 27 patients (16 females, 11 males) with age range of 18 to 70 years were included in the study.

Selected medical review showed that patients included had used topical hydrogel pads (OcuMend, Cearna Inc., Chicago, IL) containing Arnica 50 M (10) 50% and Ledum 50 M (10) applied bilaterally after surgery through postoperative day 6 at each postoperative visit.

The results of everyday progression in patients were evaluated by their respective surgeons and assigned a subjective physician-patient rating score comparing each patient's observed healing compared with expected healing if not using Arnica/Ledum.

Photographs in each examination also were recorded.The median duration of follow-up was 7 days, range from 1 to 14 days.

According to the rating of physician examined the results, the proportions of patients with markedly accelerated healing were 38.5% (5 of 13), 85.7% (6 of 7), 60.0% (12 of 20), and 51.9% (14 of 27) at POD 1 to 2, 3 to 5, 6 to 8, and overall, respectively.

The proportions of patients with accelerated healing at the same time points were 15.4% (2 of 13), 14.3% (1 of 7), 30.0% (6 of 20), and 37.0% (10 of 27), respectively.


The proportion of patients using Arnica/Ledum with markedly accelerated healing was significantly more than the proportion of those demonstrating no appreciable difference from expected at (post operative day) POD 3 to 5 (85.7% vs. 0%, p = 0.05), POD 6 to 8 (60.0% vs. 10.0%), and overall (51.9% vs. 11.1%, p = 0.05) without inducing any adverse effects.


Dr. Lee HS, the lead author said, "The preliminary results from this study demonstrate that the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) may be effective in reducing postoperative ecchymosis....,after oculofacial surgery".


Taken together, topical Arnica may be considered as a functional food to accelerated the healing of ecchymosis

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(2) The effectiveness of postoperative intervention in patients after rhinoplasty: a meta-analysis by Lee HS1, Yoon HY1, Kim IH1, Hwang SH2.(PubMed)
(3) Is There a Role for Arnica and Bromelain in Prevention of Post-Procedure Ecchymosis or Edema? A Systematic Review of the Literature by Ho D1, Jagdeo J, Waldorf HA.(PubMed)

A Simple Drink That Exerts Maximum Protection of Your Bone

Kyle J. Norton

"Let foods be your medicine and let medicines be your food", using foods as medication has been a dream of many scholars and scientists over past many centuries.

In order to achieve these, consumption of whole food medicine must accompany with moderated exercise, change of diet and life style.

Evidence from laboratory studies opinionated, regular drinking of green tea improved bone health and reduced risk of osteoporosis and fractures.

Bone health is measured by bone mineral density which has an direct influence in risk of osteoporosis and fractures.

There are numbers of bone diseases, including include osteoporosis, rickets, osteomalacia, osteogenesis imperfecta, marble bone disease (osteopetrosis), Paget disease of bone, and fibrous dysplasia.

And osteoporosis is most frequently occurrence in aging population.

Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. 

It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries.

If you experience symptoms of lower back pain, loss of height over time, a stooped posture, easy bone fracture, neck and back pain,... , you may have osteoporosis. 

Truly, bone diseases affect normal growth and development that can lead to weakness and/or deformity. 

The causes of bone diseases may be associated to genetic abnormalities, nutritional deficiencies, hormonal disorders, infections, cancers..... and other conditions.

According to the general belief and the recommendation of health researchers, good diet and physical exercise may play an important role of skeletal mass at the end of adolescence and these bone mass are remained as the conservation of it during adult life(1).

Attending normal exercise and intake of bone enhancing food at young adult life may protect ourself against risk of bone diseases as we age.

However, the study did mention the effect of diet and exercise in influence of hone health in muscular diseases as in many cases, they are correlated.

In compared to physical inactivity and non weight bearing activities, weight bearing activities in adulthood., such as walking, running. have a greater effect in improved bond mass. However, Intense training may cause damage, promptly repaired, as in stress fractures observed in many instances.

Dr. Branca F, at the National Institute of Nutrition in Rome said, "Calcium intake should also be analysed in the light of other dietary factors affecting the balance between absorption and excretion, and in combination with a number of other minerals, trace elements and bioactive substances with an impact on bone metabolism".

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.

However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But adding a slice of ginger will benign the problem.

According to Texas Tech University Health Sciences Center, green tea lovers have a reduced risk of lower bone mineral density due to its bioactive components with bone-protective properties.

The study also found that, regular green tea drinking promotes bone health in bone mineral loss menopausal women through increased bone mass, thus reducing risk of osteoporosis, a common disease in aging population.

Furthermore, intake of green tea also protected early onset of bone mineral loss in obese subjects.

Other study conducted by the same group of researchers also stated, the bone density protective effect of green tea may involve the bioactive components' effects in decreased risk of fracture by supporting osteoblastic activities while suppressing osteoclastic activities as well as attenuating oxidative stress in promoted healthy levels of bone mineral density.

In postmenopausal osteopenic women study, green tea with optimized dose of polyphenols showed an enhanced osteoprotective efficacy in improved bone mass, microarchitecture integrity, and bone strength observed through the advanced imaging technology.


Dr, Shen CL, the lead author in the studies said, " Tea polyphenols enhance osteoblastogenesis and suppress osteoclastogenesis in vitro" and "Animal studies reveal that intake of tea polyphenols have pronounced positive effects on bone as shown by higher bonemass and trabecular bone volume, number, and thickness and lower trabecular separation via increasing boneformation and inhibition of bone resorption, resulting in greater bone strength".

Promisingly, in a total study of 171 postmenopausal osteopenic women to compare the efficacy of green tea polyphenols (GTP) supplement and/or Tai Chi in risk of osteoporosis, randomly assigned to four groups: (1) placebo (500 mg starch/day), (2) GTP (500 mg GTP/day), (3) placebo + TC (placebo plus TC training at 60 min/session, three sessions/week), and (4) GTP + TC (GTP plus TC training).for 6 months, intake of green and tai chi exercise groups increased bone-specific alkaline phosphatase(bone protective glycoprotein found on the surface of osteoblasts) and improved BAP/(tartrate-resistant acid phosphatase, osteoclast increased risk of bone turnover)/TRAP ratio.

Additionally, group received also green tea showed a significant improved muscle strength in postmenopausal women with osteopenia.

Taking together, green tea may be served as functional food to protect bone health, particularly, the bone mineral density in all people with/ without risk of osteoporosis.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Physical activity, diet and skeletal health by Branca F(PubMed)
(2) Green tea and bone health: Evidence from laboratory studies by Shen CL1, Yeh JK, Cao JJ, Chyu MC, Wang JS.(PubMed)
(3) Green tea and bone metabolism by Shen CL1, Yeh JK, Cao JJ, Wang JS.(PubMed)
(4) Tea and bone health: steps forward in translational nutrition by Shen CL1, Chyu MC, Wang JS.(PubMed)
(5) Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: a 6-month randomized placebo-controlled trial by Shen CL1, Chyu MC, Yeh JK, Zhang Y, Pence BC, Felton CK, Brismée JM, Arjmandi BH, Doctolero S, Wang JS.(PubMed)
(6) Bone disease in post-transplant patients by Jeon HJ1, Kim H, Yang J.(PubMed)