^^^^How to Prevent and Treat Infectious Diseases Naturally and Effectively, MEDLINE Studies Suggestions

Kyle J. Norton 

Including green tea as a beverage in your diet may have a therapeutic and positive effect in reduced risk and treatment of bacterial and viral infectious diseases, some scientists suggested.

The results of the analysis were carried out by numbers of institutes, including the Yonsei University and punished on online medical literature.

Green tea, is a precious drink processed numbers of health benefit known to almost everyone in Asia and Western world.

According to Review provided by VeriMed Healthcare Network. intake of green tea 2 to 4 cups per day  by steep covered 5 to 10 minutes for leaf or flowers and 10 to 20 minutes for roots was  associated to support immunity while providing antibacterial and antiviral activity.

Also, green tea (Camellia sinensis) extract of 250 to 500 mg daily, enhanced immune function due to its antioxidant, anti-inflammatory, and immune effects.

Moreover, tannin, green tea derived polyphenols and other related compounds, in the study to investigate the anti-viral effects of tannins on 12 different viruses including both enveloped viruses (influenza virus H3N2, H5N3, herpes simplex virus-1, vesicular stomatitis virus, Sendai virus and Newcastle disease virus) and non-enveloped viruses (poliovirus, coxsachievirus, adenovirus, rotavirus, feline calicivirus and mouse norovirus) researchers suggested that application of tannin reduced some viral infectivity in compared to persimmon (Diospyros kaki) with more than 4-log scale against all of the viruses tested.

More importantly, the differentiation of epigallocatechin-3-gallate (EGCG) effect against viral infections also indicated that EGCG injection in solution type and powder types over extended periods at various temperature conditions exerts a strong effect in inhibited the tested human influenza A/H1N1 virus.

Green tea extract in the study also demonstrated potent viral inactivating activity for over a period of up to 2 months.

These results suggested that adding green tea supplement GTE may provide a greater than 4 log10 reduction of viral titers at a wide range of temperatures.

Dr. Lee YH, after taking intoaccount of other co and confouders said, "GTE-based antiviral agents could be formulated as a safe and environmentally friendly personal hygiene against viral infections".

The findings showed that green tea and green tea extract may be considered as function foods in reduced risk and treatment of infectious diseases caused by bacterial and viral invasion.

However, intake of green tea supplementations should be taken with extreme care as acute liver toxicity has been reported in numbers of cases.

Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Measle  Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
(2) Inactivation of Pathogenic Viruses by Plant-Derived Tannins: Strong Effects of Extracts from Persimmon (Diospyros kaki) on a Broad Range of Viruses
Kyoko Ueda, 1 Ryoko Kawabata, 1 Takashi Irie, 1 Yoshiaki Nakai, 2 Yukinobu Tohya, 3 and Takemasa Sakaguchi 1 (PMC)
(2) Evaluation of green tea extract as a safe personal hygiene against viral infections by Lee YH#1, Jang YH#1, Kim YS1, Kim J2,3, Seong BL1,4.(PubMed)

How to Treat Lower Back Pain Efficiently and Naturally, According to Studies of MEDLINE database's Suggestion

Kyle J. Norton


Green tea and its bioactive catechin epigallocatechin 3-gallate (EGCG) may have a therapeutic and positive effect in ameliorated symptoms and treatment of chronic back pain, some scientists suggested.

Green tea is a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world.

Back pain is a condition of Musculo-Skeletal disorders(MSDs) of the spine caused by various factors, including bone fractures, muscle or ligament injure, arthritis, herniated discs. aging,....


Application of biologically active polyphenol epigallocatechin 3-gallate (EGCG) demonstrated a significant effect in reduced back pain through facilitate anti inflammatory and anti-catabolic activity in patients with intervertebral disc (IVD) disease due to age-related changes in the adult disc in induction of back pain.

According to the study by the Institute for Biomechanics (D-HEST), ETH Zurich ingestion of green tea EGCG on back pain patients, human IVD cells isolated from patients undergoing surgery due to degenerative disc disease (n = 34) and cultured in 2D or 3D indicated that the phytochemical inhibited levels of inflammatory response activated by IL-1β, a cytokine protein produced by macrophages, with function in contributed to the inflammatory pain hypersensitivity in the site of infection observed by the reverse transcription polymerase chain reaction (qRT-PCR), western blotting, enzyme-linked immunosorbent assay (ELISA), immunofluorescence and transcription factor assay.

Further more, application also displayed a strong effect in reduced expression of
p38 mitogen-activated protein kinases in mediated inflammatory factors of IL-1β in responded to stress stimuli.

Also, according to the Institute for Biomechanics (D-HEST), in the investigation of the analgesic properties of EGCG, by the von Frey filament test in Sprague-Dawley rats (n = 60), green tea EGCG injection also significantly inhibited the expression of pro-inflammatory mediators as expressed in above and reduced matrix metalloproteinases which have been found to associate to pro-inflammatory cytokines, chemokines and other proteins to regulate varied aspects of inflammation and immunity.

Moreover, in the radiculopathic pain component, researchers also indicated that EGCG inhibited the inflammation in precipitated back pain through modulation of the activity of IRAK-1 in glucose metabolism and insulin sensitivity in skeletal muscle and p38, c-Jun N-terminal kinases (JNK) and nuclear factor NF-κB in responded to stress stimuli in mediated production of pain related pro inflammatory cytokines such as IL-1β.

Some researchers postulated that back pain may also induced by muscle degeneration and impairment nerve injury, leading to increased levels of reactive oxygen species in induced tissue apoptosis.

In crushing of the sciatic nerve induced back pain in tested animal, application of green tea EGCG improved motor function in the toe spread and foot positioning and gain in the percentage motor deficit.

More importantly, EGCG expressed a significant effect in recovery of sensory innervation in neuropathic pain-like syndrome and improvement of muscle tissues from injured limb with severe histopathological alterations at the end of week 3 post-surgery in treated animals.


According to the RT-PCR assay, EGCG treatment also normalizing the Bax/Bcl-2 ratio, abnormal ratio of the Bax/Bcl-2 ratio has been found to associate in induction of nerve cell apoptosis as well as inhibited levels of p53 with function in regulated the cell death cycle at days 3 and 7 post-surgery.

These results demonstrated a important effect of green tea EGCG in enhanced functional recovery, protected muscle fibers from cellular death, and improved morphological recovery in skeletal muscle after nerve injuries.


However, in the study of caffeine activity in the modulation of pain perception in chronic pain states of 131 patients with chronic low back pain (64 men and 67 women; mean age = 42.1 years; mean duration of pain = 6.1 years) referred to a multidisciplinary pain clinic over a 2-year period, researchers found that in compared to caffeine intake regardless concentration, cffeine is not related to the global experience of pain and disability in patients with chronic low back pain, although high caffeine use may be embedded in a context of other unhealthy life-style behaviors.

Taken together, green tea and its bioactive component epigallocatechin 3-gallate (EGCG) may be considered as functional food in reduced back pain caused by physical damage of the spine and injured nerve cells. Intake of green tea supplement should be taken exceptional care as some cases of liver acute toxicity have been reported in medical literature.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Epigallocatechin 3-gallate suppresses interleukin-1β-induced inflammatory responses in intervertebral disc cells in vitro and reduces radiculopathic pain in rats by Krupkova O1, Sekiguchi M, Klasen J, Hausmann O, Konno S, Ferguson SJ, Wuertz-Kozak K.(PubMed)
(2) (-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury by Renno WM1, Al-Maghrebi M, Al-Banaw A.(PubMed)
(3) Caffeine and chronic low back pain by Currie SR1, Wilson KG, Gauthier ST.(PubMed)

How to Prevent Onset of Alzheimer’s disease, US National Library of Medicine Studies Suggested

By Kyle J. Norton

Coffee intake may have a positive implication in reduced risk of early onset of Alzheimer’s disease, a respectable joint study suggested.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

Alzheimer’s disease is generalized and progressive neuro degenerative disease due to aging.

In a rat model for Alzheimer’s disease (AD) induced by phosphoprotein phosphatase 2A (PP2A), eicosanoyl-5-hydroxytryptamide (EHT), researchers showed that components found in coffee exhibited a protective effect against AD, through inhibited expression of the I2(PP2A), or SET protein involved multiple cellular processes in the brains.

More importantly, oral administration of the supplement for 12 months showed a strong attenuated all the defects of cognitive impairment, including tau hyperphosphorylation, and elevated levels of cytoplasmic amyloid-β protein caused by phosphoprotein phosphatase 2A (PP2A) injection.


Dr. Basurto-Islas G, the lead author in the joint study said, ” possibility that EHT may make a substantial contribution to the apparent neuroprotective benefits associated with coffee consumption as evidenced by numerous epidemiologic studies indicating that coffee drinkers have substantially lowered risk of developing AD”.

Further more, Dr. Wierzejska R in the evaluated effects of caffeine coffee in dietary factors which might prolong mental agility, said, ” moderate coffee consumption in fact has a lower the risk for common neurodegenerative conditions, i.e. Alzheimer’s and Parkinson’s diseases” and “Possibly, in the future experts will recommend drinking coffee not only to satisfy individual taste preferences but also to decrease age-related mental deterioration.”.

Others, in the concerns of the high consumption of coffee in effect of individual’s health through evaluating database of online medical literature, researchers found that coffee-drinking habits, and/or the quantity of coffee consumption, have a significantly reduced risk of dementia/AD, and other chronic diseases, but the the underlying mechanisms are not fully understood, when comparing coffee drinkers with non-drinker.

Taking together, regular drinking of caffeine coffee in a moderated amount daily may have a positive effect in attenuated risk and progression of Alzheimer’s disease and caffeine may be considered as a novel therapy for treatment of Alzheimer’s disease.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Therapeutic benefits of a component of coffee in a rat model of Alzheimer’s disease by Basurto-Islas G1, Blanchard J1, Tung YC1, Fernandez JR2, Voronkov M2, Stock M2, Zhang S3, Stock JB4, Iqbal K5.(PubMed)
(2) Can coffee consumption lower the risk of Alzheimer’s disease and Parkinson’s disease? A literature review by Wierzejska R1.(PubMed)
(3) Possible health effects of caffeinated coffee consumption on Alzheimer’s disease and cardiovascular disease by You DC1, Kim YS, Ha AW, Lee YN, Kim SM, Kim CH, Lee SH, Choi D, Lee JM.(PubMed)

How to Prevent Vulvar Cancer Naturally, US National Library of Medicine Studies Suggestions

Kyle J. Norton

Adding a portion of carrots in women daily diet may have a profound and positive effect in reduced risk, progression and treatment of vulvar cancer, some scientists suggested.

The investigations were conduced by numbers of respectable university in women associated to higher risk of vulvar cancers, including the Tampere University Central Hospital and Mercer University  and the results were published on online literature.

You can view the detail in abstracts of the studies by clicking any of the resources link


Vulvar cancer is a medical condition characterized by cell growth irregularly and disorderly in the tissue of the area of skin surrounded the urethra and vagina, including the clitoris and labia.

At the later stage, the cancerous cells may travel a distance away from the original site to infectious other healthy tissue.

The results of evaluation were reported by some respectable institutes and published on the online medical literature.


Carrot, a root vegetable with orange color is a sub spices of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.

Nutrients
1. Carbohydrates
2. Sugars
3. Fibre
4. Fat
5. Protein
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C

13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Molybdenum
18. Phosphorus
19. Potassium
20. Sodium


In the study to analyze the association between body mass, selected indicator food intake, and vulvar cancer risk of 125 women aged 80 years or younger with histologically confirmed diagnosis of invasive vulvar cancer, admitted to a network of general and teaching hospitals in the greater Milan area in compared to Control subjects of 541 patients admitted to teaching and general hospitals in Milan for acute conditions, researcher found that carrot consumption is associated to reduce risk of the cancer.

In compared to others in exerted inconsistent association of risk of vulvar cancer such as milk, meat, liver, alcohol and coffee consumption, carrot demonstrated a significantly decreased risk ratio of 1.4.

The results suggest that certain factors in the dietary and nutritional aspects may process related mechanisms in risk of vulvar cancer.

Further analysis of carrot effect in risk of vulvar cancer inregard of the micro nutrients expression, researchers found that serum concentrations of vitamin A (retinol), vitamin E (alpha-tocopherol) and total carotene were lower in women with vulvar cancer but no difference to women with other types of female reproductive cancer such as cervical, endometrial and ovarian carcinomas.

In compared to healthy control, the mean levels of vitamin A was significantly less in patients with vulvar cancer.

However, according to the Mercer University, in analysis of the patients with metastasising carcinoma of the uterine cervix or recurrent disease after failure of surgical and/or radiation and chemotherapy therapy.

13-cis-retinoic acid and interferon alpha-2 a in the treatment of squamous cell carcinoma of the cervix in 6 patients with locally recurrent or metastasising squamous cell carcinomas, five of the uterine cervix, one of the vulva. in the period of 52 days, median survival time 107 days, filed the results as follows
* 3 women experienced progression of disease uninfluenced by therapy.
* 1 patient with multiple subcutaneous lymph node metastases showed mixed response for a short period of 3 weeks before progression and eventual death.
* 1 patient had no change or disease for 13 months with subsequent progression and eventual death after 22 months.
* One patient could not be evaluated for an allergic reaction after only 15 days of treatment.

The application also induced adverse effects of "flu-like symptoms", skin irritations, conjunctivitis sicca and chileitis, all WHO 1-2.

Overall toxicity is extremely low in compared to standard chemotherapy, but is not negligible.

The failure of study in treatment of advance vulvar cancer may be due to numbers of implication,  researchers at the Mercer University suggested , "this might be due to the small number of cases, which is a common problem in immunotherapeutic studies. Moreover, very unfavourable patient selection criteria in our study compared to primarily untreated patients may also have contributed to different response rates. However, in our opinion the tested regimen cannot be considered sufficiently effective in patients suffering from pretreated, recurrent squamous cell carcinoma of the cervix or vulva".

Taken together, Carrot with high amount of nutrients and antioxidants may be used as functional food in reduced risk and combined with standard therapy for treatment of vulvar cancer. However, multi centers and large sample size studies are necessary to re confirm this viability.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Selected food intake and risk of vulvar cancer by Parazzini F1, Moroni S, Negri E, La Vecchia C, Dal Pino D, Cavalleri E.(PubMed)
(2) Serum vitamins A and E and carotene in patients with gynecologic cancer by Heinonen PK1, Kuoppala T, Koskinen T, Punnonen R.(PubMed)
(3) [13-cis retinoic acid and interferon-alfa-2a as palliative therapy in pretreated, recurrent squamous epithelial carcinoma of the cervix uteri and vulva] by [Article in German](PubMed)

How to Stop Hair Loss and Improve Hair Diameter & Density Naturally, US National Library of Medicine Posted

Kyle J. Norton

Researchers may have  found ingredients for treatment of  hair loss pattern.

Supplementation with specific omega 3 & 6 and antioxidants acts efficiently against hair loss, improves hair density and reduces the telogen percentage and the proportion of miniaturized anagen hair, the Laboratoires innéov study suggested

The results of the investigation were published on online literature.

Omega-3& 6 fatty acids are phytochemincals in the class of lipids, found abundantly in dark-green leafy vegetables, grains, legumes, nuts,…

Antioxidants are substances with function in inhibited oxidation caused by reactive oxygen species.

Many antioxidants also act as free radical scavengers, such as vitamin C, D and E.

Human have to absorb Omega 3 & 6 from other sources as they do not produce them.

In the total of 120 healthy female subjects participated in this 6-month, randomized, comparative study to evaluate the change in hair density on standardized photographs primary with. secondary endpoints to include changes in telogen hair percentage and diameter distribution of anagen hair (>40 µm vs. ≤40 µm) measured by trichogram, researchers found that intake of omega 3 & 6 and antioxidants display a significant effect in reduced hair loss and promoted hair growth.

According to the photograph assessment, the application demonstrated a superior improvement in hair density.

The telogen hair percentage was significantly (P < 0.001) reduced in the supplemented group.

The proportion of nonvellus anagen hair (>40 µm) increased compared to the control group.

Trichometer index in supplemented group expressed a substantial increment of hair growth, in compared to loss in control group. 

Also, according to the doctors' final photograph assessment reported, oral administration of Omega 3 & 6 supplement reduced hair loss, improved hair diameter and hair density in most of women who were assigned to treatment group.

After aking into account of other co and con founders, Dr. Le Floc’h C, the lead scientist said, “A large majority of supplemented subjects reported a reduction in hair loss (89.9% of subjects at 6 months), as well as an improvement in hair diameter (86.1%) and hair density (87.3%)”.

Truly, the study of 6-month supplementation with omega 3&6 and antioxidants no doubt expressed a significant effect in inhibited hair loss and improved hair density and reduced telogen percentage and miniaturized proportion of anagen hair.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca



Sources
(1) Effect of a nutritional supplement on hair loss in women by Le Floc’h C1, Cheniti A, Connétable S, Piccardi N, Vincenzi C, Tosti A.(PubMed)

Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-62

How to Protect Yourself From Next Influenza Season Naturally and Permanently, PubMed Suggested

Kyle J. Norton


Including green tea, the Camellia sinensis leaves as a beverage in your daily diet, may have a therapeutic and positive effect in protection against influenza, some scientists suggested.

Influenza, is also known as "the flu", is an infectious disease caused by an influenza virus.

Green tea, is a precious drink processed numbers of health benefit and known to almost everyone in Asia and Western world.


In the investigated the green tea effect in reduced risk of influenza viral overspreading in general population, researchers at the Yonsei University conducted a study to evaluate catechin derivatives with different alkyl chain length and aromatic ring substitutions at the 3-hydroxyl group synthesized from epigallocatechin (EGC) and (+)-catechin (C) activity against influenza virus.

According to the experiment, application of catechin derivatives, carrying moderate chain length (7-9 carbons) exerted a pronounced effect in inhibited over expression of the virus in compared to those with aromatic rings.

Interestingly, injection of the 5'-hydroxyl group did not significantly contribute to antiviral activity against trihydroxy benzyl moiety.

However, administration of both derivatives demonstrated an inhibitory effect for all six influenza subtypes tested including three major types of currently circulating human influenza viruses (A/H1N1, A/H3N2 and B type), H2N2 and H9N2 avian influenza virus, through strongly inhibited adsorption of the viruses on red blood cell (RBC).

In vivo, the derivatives also expressed an impressive activity in restricted the growth of avian influenza virus with minimum inhibition concentration (MIC) of 5-10 microM far exceeding the dose of conventional medicine oseltamivir or M2 proton channel inhibitor amantadine with the same purposes.


Further analysis suggested that the derivatives isolated from actechin inhibited effect were attributed to the mediation and interaction with hemagglutinin (HA)/viral membrane at the initial stage of infection.


Dr. Song JM, the lead author, after taking account of all assessment said, "The broad spectrum activity against various subtypes of influenza viruses may complement the limitations of current antivirals and contribute for managing potentially emerging influenza pandemic".


Importantly, in the comparison of the theaflavins fraction (TF80%, with a purity of 80%) and three theaflavin (TF) derivatives potently inhibitory effects against influenza virus in vitro, scientists at the Chinese Academy of Medical Sciences & Peking Union Medical College indicated that all applications displayed significant inhibitory effects on the HA of three different subtypes of influenza virus strains [A/PR/8/34(H1N1), A/Sydney/5/97(H3N2) and B/Jiangsu/10/2003] with 50% inhibitory concentration (IC(50)) values ranging from 9.27 to 36.55 μg/mL, probably though expression and interaction on HA as above differentiation.


Additionally, TF derivatives inhibited the over expression of viral particle infectivity consistently and corelatively with the inhibitory effect on HA.

According to the qPCR and nuclear localization of the influenza virus vRNP assays, all applications exerted anti infectivity by interrupting the viral replication and also decreased the production of inflammatory cytokine IL-6 in induction of serious tissue injury and apoptosis.


The above evaluation were supported by the Yonsei University study of the polyphenolic compound catechins ((-)-epigallocatechin gallate (EGCG), (-)-epicatechin gallate (ECG) and (-)-epigallocatechin (EGC)) from green tea in inhibited influenza virus replication in cell culture and for potentially direct virucidal effect.
According to the results, among all compound selected in the assessment, EGCG and ECG were found to be potent inhibitors of influenza virus replication in MDCK( in a suitable transfection host for influenza research) cell culture, including A/H1N1, A/H3N2 and B virus, observed in all influenza virus subtypes tested, with 50% effective inhibition concentration (EC50) of EGCG, ECG, and EGC for influenza A virus at doses of 22-28, 22-40 and 309-318 microM, respectively.


The effective compounds EGCG and ECG also displayed an exhibited anti hemagglutination activity, similar to those in above studies.

Moreover, in compared to the EGCG and ECG anti influenza virus efficacy, researchers surprisingly found that at high concentration, EGCG + ECG also suppressed viral RNA synthesis in MDCK cells whereas EGC failed to show similar effect and EGCG + ECG inhibited the neuraminidase activity more effectively than the ECG.

These results reaffirmed that the expression of green tea biocative polyphenols antiviral effect of catechins on influenza virus is mediated not only by specific interaction with HA, but also alter the physical properties of viral membrane, Dr. Song JM, the lead author of the study suggested.


Taken together, green tea with abundant phytochemical polyphenols may be considered as a functional food for reduced risk, progression and treatment of infleunza infection.

Reprint of this article is welcome with author name and link to the article sources intact https://kylejnorton.blogspot.ca/2018/03/the-magic-of-camellia-sinensis-leaves.html


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Biological evaluation of anti-influenza viral activity of semi-synthetic catechin derivatives by Song JM1, Park KD, Lee KH, Byun YH, Park JH, Kim SH, Kim JH, Seong BL.(PubMed)
(2) In vitro anti-influenza virus and anti-inflammatory activities of theaflavin derivatives by Zu M1, Yang F, Zhou W, Liu A, Du G, Zheng L.(PubMed)
(3) Antiviral effect of catechins in green tea on influenza virus by Song JM1, Lee KH, Seong BL.(PubMed)

How to Optimize Your Immune System Against Pathogens Quickly and Permanently, PubMed Suggested

By Kyle J. Norton

Including a portion of lentil in your diet will have a profound and substantial effect in modulated immune response in acute phase of infection, some scientist suggested

Lentil is a type of pulse and tiny legumes that can be cooked quickly and rich in protein and fiber, belongings genus Lens the Fabaceae family, native to Middle East.

Immune response is a natural reaction of immune system to protect our body against invasion of foreign substances.

In acute phase of infection, immune system initiated production of of proinflammatory Th1 cytokines in activated interleukin-12 (IL-12) and gamma interferon (IFN-γ) and other pro inflammatory factors such as TNF beta in response to detect, engulf and destroy pathogens and apoptotic cells through macrophages.

These activities played an important in induced apoptosis and reduced proliferation of bacteria or virus by attaching to the surface of the injure cells to initiation of alternation. however, over production of pro inflammatory expression may indeed cause substantial adverse effects in tissue destruction, and, in some cases, shock and death.

Type 1 T helper (Th1) in response to tissue damage and injure also activated macrophages which are responsible for cell-mediated immunity and phagocyte-dependent protective activity.


In the concerns of lectins adverse effecs may pose a potential threat to consumers due to their capacity to induce histamine release from basophils, after investigating over 16 common dietary produceds containing lectins researchers found that most plant lectins induce human basophils to produce interleukin 4 (IL-4) a anti inflammatory cytokine, which plays an important role in stimulated secretion of T cells and IL-13 another cytokines works conjunction with IL-4 in promoted the expression of T helper 2 (Th2) responses and regulation of Immunoglobulin E (IgE) synthesis.


All these expressed a significant effect of dietary lectin in reduced over expression of pro inflammatory factors in immune system during acute phase of infection in induced further cell damage and death in the infectious site through secretion of anti inflammatory cytokines without decreasing the immune protective activities.


Truly, further examine also found that concanavalin A, lentil lectin, phytohemagglutinin, , triggered basophils to release IL-4 at concentrations of up to 1 ng/10(6) basophils which in turn orchestrated the release of IL-13 and histamine and levels of IL-4 and IL-13 release reached a maximum after 4-6 h and more than 18 h, after injection, , respectively.


These activities demonstrated a significant effect of lentil lectin in inducing early IL-4 required to switch the immuneresponse towards a Th2 response and type I allergy, involving immunoglobulin E (IgE)–mediated release of histamine and other mediators from mast cells and basophils.

Indeed, the relative balance between Th1 and Th2 cytokines appears crucial, as Th1 cells activated immune response during the early state of body injure or damage through evoking cell-mediated immunity and phagocyte-dependent inflammation, in stimulated production of several pro inflammatory cytokines such as interferon (IFN)-gamma, interleukin (IL)-2 and tumor necrosis factor (TNF)-beta which may also cause damage to the cell of the infectious region, leading to permanently additional damage to the tissues and Th2, under response to over expression of pro inflammatory cytokines stimulated the production of IL-4, IL-5, IL-6, IL-9, IL-10, and IL-13 of anti inimflammatory mytokines in evoked strong antibody responses (including those of the IgE class) and eosinophil accumulation, and inhibited several functions of phagocytic cells as indicated above.


Taken together, Lentil lectin may have a anti inflammatory effect in reduced over expression of pro inflammatory factors in initiation of symptoms of fever, headache, swelling, redness, loss of appetite, muscle stiffness through activating production of anti inflammatory mytokines.

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Author Biography
Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Role of Th1 and Th2 Cytokines in Immune Response to Uncomplicated Plasmodium falciparum Malaria by Donato Torre,1,* Filippo Speranza,1 Massimo Giola,1 Alberto Matteelli,2 Roberto Tambini,1 andGilberto Biondi1(PMC)
(2) Dietary lectins can induce in vitro release of IL-4 and IL-13 from human basophils by Haas H1, Falcone FH, Schramm G, Haisch K, Gibbs BF, Klaucke J, Pöppelmann M, Becker WM, Gabius HJ, Schlaak M.(PubMed)
(3) T-cell subsets (Th1 versus Th2) by Romagnani S1(PubMed)