Monday, 2 October 2017

Food Therapy: Coffee Intake in reduced Risk of Stroke, Particularly in Women

By Kyle J. Norton


Coffee, second to green tea is a popular and social beverage all over the world, particular in the West, made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

A stroke is medical condition characterized by interrupted blood supply, thus reducing oxygen and nutrients delivery to the brain, resulting in death of brain cells.

Intake of coffee and coffee caffeine may have a profound effect in reduced risk of stroke incidence, a renowned institute study suggested.

In a third National Health and Nutrition Examination Survey (1988-1994; NHANES III) data to examine coffee consumption and stroke with participants aged ≥17 years old, researchers found that
coffee intake of this population showed a significantly inverse association to  stroke risk incidence,  regardless to smoke status.

Interestingly, the study also discovered that frequent coffee drinkers displayed a less occurrence of heart failure, diabetes, and hypertension but risk of high cholesterol for those consuming ≥3 cups per day. 

Dr. Liebeskind DS, the lead author said, "Heavier daily coffee consumption is associated with decreased stroke prevalence" and ". Multivariate analyses revealed an independent effect of heavier coffee consumption (≥3 cups/day) on reduced stroke".

Further more, in an analyzed data from a prospective cohort of 83,076 women in the Nurses' Health Study without history of stroke, coronary heart disease, diabetes, or cancer at baseline, with coffee consumption assessed first in 1980, then repeatedly every 2 to 4 years, and follow-up through 2004, researchers at the Harvard School of Public Health filed the following results
1. The relative risk ratio of stroke in participants coffee consumption (<1 cup per month, 1 per month to 4 per week, 5 to 7 per week, 2 to 3 per day, and >or=4 per day) were 1, 0.98, 0.88, 0.81, and 0.80 repetitively.
2. Intake of coffee and coffee caffeine daily and regularly showed a significantly positive effect in reduced stroke risk after taking in to count of other favors, including high blood pressure, hypercholesterolemia, and type 2 diabetes.
3. Risk of stroke also associated stronger correlation among never and past smokers (RR for >or=4 cups a day versus <1 cup a month, 0.57) than among current smokers (RR for >or=4 cups a day versus <1 cup a month, 0.97).
4. Decaffeinated coffee intake also was associated to a trend in lower risk of stroke after adjustment for caffeinated coffee consumption.
5. Caffeine consumption of other beverage do not associate to risk or reduced risk of stroke.

The findings suggested that long-term coffee consumption was not associated to risk of stroke but modestly reduce risk of stroke.

Promisingly, a Asian study of data obtained from the Health Examinees (HEXA) Study, involved 146,830 individuals aged 40-69 years demonstrated that high coffee consumption was associated with a 38% lower odds ratio for stroke in women in compared to (none drinkers vs. ≥ 3 cups/day drinkers in women but not in men.

The expression of coffee intake in reduced risk of stroke also found greater in women who are healthy, younger, non-obese, non-hypertensive, non-diabetic, non-smokers, and non-alcohol drinkers.

Taking together, there is no doubt that intake of coffee daily and regularly have a remarkable effect in reduced risk of stroke, particular in women.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The coffee paradox in stroke: Increased consumption linked with fewer strokes by Liebeskind DS1, Sanossian N2, Fu KA2, Wang HJ3, Arab L4(PubMed)
(2) Coffee consumption and risk of stroke in women by Lopez-Garcia E1, Rodriguez-Artalejo F, Rexrode KM, Logroscino G, Hu FB, van Dam RM.(PubMed)

Herbal Therapy: Green tea, the Best in Prevention and Treatment of Chronic Inflammatory Diseases

By Kyle J. Norton


People who turn to herbal Medicine for treatment of disease in avoidance of adverse effects induced by conventional medicine must be patient as the alternative treatment can only ease symptoms gradually, depending to stages of the treatment which directly address to the cause of the disease.

Good news for people with chronic inflammatory diseases, green tea polyphenols (GrTPs) is found to reduced risk and progression of the diseases through the exhibition of potent antioxidants in regulating vital signaling pathways involved production of inflammatory cytokines. a renowned institute study suggested

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger in each drink will attenuate the expression.

Chronic inflammation diseases are medical conditions caused by over reaction of the immune system in protection against microbial invasion and damage to organs due to injure, affecting tissue healing process, which can lead to life-long debilitation and loss of tissue function and organ failure.

According to the University of Kentucky Medical Center, green tea phytochanical polyphenols protected our body against inflammation through actions in intercepted the surge of inflammatory markers like cytokines and production of cyclooxygenase-2 in innated anti inflammatory mytokins.

In chronic Inflammatory Bowel Disease patients, catechin isolated from green tea enhanced the antioxidant production such as such as glutathione peroxidases (GPO) and glutathione (GSH), in significantly inhibited excessive oxidative stress through direct or indirect in reducing the oxidative damages to the colon.

Dr. Fan FY, the lead author said, " catechins can exert their significant anti-inflammatory properties by regulating the activation or deactivation of inflammation-related oxidative stress-related cell signaling pathways( involved proinflammation specifically)".

Particularly, the study also specified, the impression of antioxidant catechin in stabilized the structure of the gastrointestinal micro-ecological environment via promoting the proliferation of beneficial intestinal bacteria and regulating the balance of intestinal flora for induction of relief in patients with IBD.

Furthermore, in psoriasis mouse model, BALB/c mice topically treated with IMQ for 6 consecutive days, displayed a significant alleviated psoriasiform dermatitis, improved the skin pathological structure by reduce the expression of epidermal PCNA(Base cells) and promoted the expression of caspase-14 involved in inflammation.

In fact, according to the study, the efficacy of Epigallocatechin-3-gallate (EGCG), for treatment of
psoriasis-like inflammation is the result of the phytochemiclal functions in anti-inflammatory, immune regulatory and antioxidant activation.

Taking together, green tea may be used as a protectively functional food in prevention and treatment of chronic inflammatory diseases, but regularly large amount injection should be avoid to prevent toxicity.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Chronic Inflammatory Diseases and Green Tea Polyphenols by Oz HS1.(PubMed)
(2) Catechins and Their Therapeutic Benefits to Inflammatory Bowel Disease by Fan FY1, Sang LX2, Jiang M3.(PubMed)

Food Therapy; Coffee and Coffee Caffeine in Reduced Risk of Cancers But Esophageal Cancer

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stage of the treatment which directly address to the cause of disease.

Intake of coffee regularly may have a profound effect in reduced risk of cancers, a recent study proposed.

Cancer is a group of diseases characterized by irregular cell growth in any tissue and organ in the body.

Coffee, becoming a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the joint study lead by the Università degli Studi di Milano-Bicocca, consumption of healthy foods, particularly coffee with rich in polyphenols might have a substantial influence in reduced prevalence of cancer incidence.

Coffee extract with high chlorogenic acids (CGAs) exhibited the beneficial biological effects in ameliorated risk of cancer through anti-inflammatory activity and anti-carcinogenic activity.

In Ras-dependent breast cancer cell line MDA-MB-231, CGAs also displayed a molecular basis of the activity and chemoprotective in induction of cell apoptosis.

Furthermore, in the review of literature in expression of the association between total, caffeinated and decaffeinated coffee consumption and melanoma risk in a dose-response meta-analysis on prospective cohort studies through searching the data base of PubMed and Embase, researchers indicated, seven studies eligible for meta-analysis, comprised 1,418,779 participants and 9211 melanoma cases. caffeine attenuated melanoma risk with a linear dose-response association between total coffee consumption.

Prevalence risk of melanoma reduced by 3% for additional cup of coffee intake per day.
Dr. Micek A, the lead author said, "coffee intake may be inversely associated with incidence of melanoma".

In further demonstrated coffee and coffee caffeine in ameliorated risk of cancer, the Cox proportional hazards regression was used to estimate multivariable-adjusted hazard ratios (HR) for coffee consumption associated with death from all cancers combined and from specific cancer types among 922,896 Cancer with 1982 as a base line, researchers at joint study lead by the American Cancer Society found that only smokers showed a a non-linear association between coffee consumption and all-cancer death but not in never smokers.

Among non-smokers,drinking 2 cup/day or more showed a significantly inverse associated with death from colorectal, head and neck and female breast cancers, but positively associated with esophageal cancer death . 

Taking altogether, coffee and coffee caffeine have a profound effects in reduced risk of many types of cancer, excepted esophageal cancer which may be attributed to long term themo effect of hot beverage intake.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins by Palmioli A1, Ciaramelli C1, Tisi R1,2, Spinelli M1, De Sanctis G1, Sacco E1,3, Airoldi C1,2,3.(PubMed)
(2) Caffeinated and decaffeinated coffee consumption and melanoma risk: a dose-response meta-analysis of prospective cohort studies by Micek A1, Godos J2, Lafranconi A3, Marranzano M2, Pajak A1.(PubMed)
(3) Associations of Coffee Drinking and Cancer Mortality in the Cancer Prevention Study-II by Gapstur SM1, Anderson RL2, Campbell PT2, Jacobs EJ2, Hartman TJ3, Hildebrand JS4, Wang Y2, McCullough ML2.(PubMed)

Sunday, 1 October 2017

Alternative Therapy: Yoga, The Best Ancient Intervention In Ameliorated Chronic Pain

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

People attending yoga lessons long terms demonstrated superior performance on measure of implicit motor imagery in reduced severity of chronic pain, compared non yoga participants.

This implication of superior motor imagery performance in yoga participants actually promoted cortical re-organization in alleviate pain associated with imagination and observation of movement, without triggering the protective pain response.

Yoga is a ancient practical technique of India, included breath control, meditation, bodily movement and gesture,..... with an aim to achieve harmonization of the body, mind, and spirit.

Chronic pain is a persistence of pain last more 12 weeks and longer.

Dr. Hartnoll SH, the lead researcher said, " Yoga practice is associated with superior motor imagery performance; an association that may be important in explaining the established rehabilitative value of yoga for chronic pain".

In a total of 36 participants (18 yoga, 18 nonyoga) matched for age, sex and handedness, undertook the hand laterality recognition task yoga group scored a magnificent faster result in compared controls (p < 0.05), including greater accuracy, faster responses to images corresponding with the dominant limb and with awkward postures, as indicated motor imagery assay.

Additionally, researchers also emphasized that yoga practiced attendees also expressed a motor imagery performance, involving awkward postures in compared control group.

Other study insisted that mind-body techniques such as yoga may be used as pain and symptom management in conjunction of non-opioid pain medication for certain chronic pain as well as improved quality of life.

Intertestingly, in study to evaluate the regular yoga practice influenced in a left/right judgement task in compared to people who do not, participant after viewing into 40 photographs of a model with their head turned to the left or right, yoga group and non yoga scored a more faster and more accurate (p=0.001) at making left/right neck rotation judgement than they were at making left/right-hand judgements, regardless of groupd. These results may be an indication that yoga may have a chronic pain efficacy through other aspects unrelated to certain tasks.


Taking together, yoga may be a safe and effective technique used for treatment of chronic pain though many mechanisms, including superior motor imagery performance. 

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Yoga practice is associated with superior motor imagery performance by Hartnoll SH1, Punt TD1.(PubMed)
(2) Are people who do yoga any better at a motor imagery task than those who do not? by Wallwork SB1, Butler DS2, Wilson DJ1, Moseley GL3.(PubMed)
(3) A Mind-Body Approach to Pediatric Pain Management by Brown ML1,2, Rojas E3, Gouda S4.9(PubMed)
(4) The effects of graded motor imagery and its components on phantom limb pain and disability in upper and lower limb amputees: a systematic review protocol Katleho Limakatso, Lieselotte Corten and Romy Parker(Systematic Reviews)

Herbal Therapy: Green Tea, the Best Functional in Reduced Risk and Treatment of chronic obstructive pulmonary disease (COPD)

By Kyle J. Norton

The use of plants for healing purposes has been predated long before the existence of modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......


Green tea may be considered as a potential pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD), a renowned institute study suggested.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will resolved the problem.

Chronic obstructive pulmonary disease (COPD) is a condition of lung disease caused by obstruction of air flow in normal breathing.

In a total of 13,651 adults from three Dutch cities examined from 1994 to 1997. observation of dietary intake estimated using a food frequency questionnaire, and flavonoid intake calculated using specific food composition tables, showed a significant effect of flavonoid intake regularly in reduced risk COPD.

According to the returned questionnaire, total catechin, flavonol, and flavone intake was positively associated with FEV1 in air flow of a deep breath and inversely associated with chronic cough and breathlessness, common symptoms of chronic obstructive pulmonary disease (COPD).

More specified, Dr. Tabak C, the lead author said, "Flavonol and flavone intake was independently associated with chronic cough only"

Furthermore, Chafuroside A (CFA), a water-soluble flavone C-glycoside, isolated from oolong tea, in oral administration exhibited at 0.5mg/kg or higher exhibited a profound effect in attenuated inflammatory symptoms in a dose-dependent manner, in experimental asthma/chronic obstructive pulmonary disease (COPD)-like model.

In fact, Biomarker profiling revealed that the CFA/SAM at 0.1mg CFA/kg equipotent to CFA at 1.0mg/kg testing result also expressed protective activity against antigen-induced airway inflammation.

Taking together, there is no doubt that green tea may be used as a therapeutic and functional food for reduced risk and treatment of chronic obstructive pulmonary disease (COPD) through expression of plant phytochemicals, but large amount intake regularly should be taken with care in prevented toxicity.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease by Grandhi S1, Donnelly LE, Rogers DF.(PubMed)
(2) Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the MORGEN Study by Tabak C1, Arts IC, Smit HA, Heederik D, Kromhout D.(PubMed)
(3) Self-assembled micellar formulation of chafuroside A with improved anti-inflammatory effects in experimental asthma/COPD-model rats by Onoue S1, Matsui T, Aoki Y, Ishida H, Nukaya H, Kou K, Yamada S.(PubMed)

14 Surprising Health Benefits and 2 Adverse Effects of Kidney beans

By Kyle J. Norton

Kidney bean is popular because of its kidney shape, strong flavor and color of reddish brown in nature, It is often an excellent dietary selection with no cholesterol and good sources of protein and mineral.

16 Surprising Health Benefits Kidney beans 
1. Food Therapy: Kidney Bean, the Anti Hperglycemic Whole Food for Obese & Over Weight Patients
2. Food Therapy: Kidney beans( Phaseolus), The Best Anti-Inflammatory Functional Foods
3. Food Therapy: Kidney Beans Uncooked May induce Gastrointestinal Dysfunction
4. Food Therapy: Kidney bean, the Anti Hyperlipidemia Natural and Functional Food
5. Food Therapy: Kidney Bean, The Anti Obesity Complications Natural functional Food
6. Food Therapy: Kidney Beans, the Potential anti-human immunodeficiency virus (anti-HIV) Natural Whole Food
7. Food Therapy: Kidney beans, The Whole Food in Reduced Risk and Treatment of Diabetes
8. Food Therapy: Kidney beans( Phaseolus), The Best Function Food for Reduced Risk and Treatment of Chronic Diseases
9. Food Therapy: Kidney Bean, The Best Natural Weight Loss Functional Food
10. Food Therapy: Kidney Beans, The Whole Food in Reduced Risk and Treatment of Colon Cancer
11. Food Therapy: Raw Kidney beans May Induce Toxicity
12. Food Therapy, Kidney bean, The Natural Whole Food with Anti-Microbial Activities
13. Food Therapy: Kidney bean, the Best Anti-cancer Healthy Whole Food
14. Food Therapy: Kidney beans, the Whole Food in Reduced Risk and Treatment of Leukemia
15. Food Therapy: Kidney Bean, the Natural Antioxidants Whole Food
16. Food Therapy: Kidney beans May Induce Risk of Intestinal Atrophy

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over laast 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Saturday, 30 September 2017

Food Therapy: Kidney beans May Induce Risk of Intestinal Atrophy

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The use of plants for healing purposes have been predated long before the existence of  modern medicine. Herbal plants have formed a fundamental sources for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Intake of kidney beans may result in increased risk of the developed intestinal atrophy, the renowned institute study suggested.

Kidney beans with kidney shape, strong flavor and color of reddish brown in nature are often the excellent dietary selection with no cholesterol, but a good source of protein and minerals.

Intestinal atrophy is the abnormality of small intestine mucous membrane, caused by bacterial infection.

According to the University of Utrecht, animal fed with kidney bean induced mucosal atrophy microscopically causing atrophy and dissection of the intestinal villus in association with lengthen crypts with cells in increased mitotic activity in compared to than normal tissues.

In compared to controls, kidney bean intake significantly decreased the goblet cells in secrete gel-forming mucins, the major components of mucus but increased in the crypt region, a gland found in the intestinal epithelium lining of the small intestine and large intestine.

Dr. Kik MJ, the lead author of the study said, " feeding Phaseolus vulgaris beans reduced the digestive and absorptive capacity of the mucosa, resulting in weight loss and diarrhea in affected pigs".

In randomized study with mice fed to chow, elemental diet, elemental diet plus concanavalin-A and elemental diet plus phytohaemagglutinin groups, group fed phytohaemagglutinin showed a strong effect of chemical compound lectin in inducing cell proliferation in the small intestine and crypt fission of the middle and distal small intestine in compared to other groups.

The study also showed that phytohaemagglutinin with high amount of lectin also induced intestinal atrophy by affecting the gastric function and mobility through increased secretion of hormone in regulated gastric acid (HCl). In fact, the effects of lectins cause significant gastric trophy on the small intestine and colon may vary between different sites in the gastrointestinal tract.

In support to the above analysis, the Christian-Albrechts-Universität study
with 30 day old male rats pairfed for 10 days with lactalbumin as a control diet or lactalbumin plus PHA or purified soybean trypsin inhibitor (STI) as a positive control (42 mg/rat/day) with or without 20 micrograms of the cholecystokinin A (CCK-A) antagonist MK 329, also found that oral administration of phytohaemagglutinin (PHA) in rats dose dependently induces growth of the small intestine through significantly increased CCK plasma levels from 0.75 to 6.67 (SEM 2.23) compared with 2.3 (0.35) pM in the control group.

The result of phytohaemagglutinin (PHA) intake in exhibit the intestine atrophy may be attributed to the lectin levels in increased production of hormone cholecystokinin in stimulated additional release of bile into the intestine.

Taking together, intake of kidney bean should be taken with care with patients with digestive problems as level of lectin may induce intestinal atrophy.



Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Pathologic changes of the small intestinal mucosa of pigs after feeding Phaseolusvulgaris beans by Kik MJ1, Huisman J, van der Poel AF, Mouwen JM(PubMed)
(2) Lectins can reverse the dsstal intestinal atrophy associated with elemental diets in mice M by SASAKI*, A. J. FITZGERALD*, G. GRANT , M. A. GHATEIà, N. A. WRIGHT* & R. A. GOODLAD§(Wiley online Library)
(3) Red kidney bean lectin is a potent cholecystokinin releasing stimulus in the rat inducing pancreatic growth byK-H Herziga, S Bardoczc, G Grantc, R Nustedeb, U R Fölscha, A Pusztaic(BMJ Journals)