Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Saturday, 29 July 2017

Herbal Therapy: Chamomile, the Antimicrobial Whole Herb Medicine in Accelerated Wound Healing

Chamomile, exerted its biotic property in accelerated the progression of wound healing by inhibiting Pseudomonas aeruginosa, in vivo.

According to the Shiraz University of Medical Sciences, treatment of 5% C. nobile ointment extract from chamomile in rat wounds infected induced by P. aeruginosa, was more effective in expression of antibacterial and wound healing activities in comparison to tetracycline, the antibiotic medicine.

The chamomile noble, in the Pseudomonas aeruginosa biofilm formation isolated from wound infections, also showed a remarkable inhibitory concentration of 6.25-25mg/ml.

Chamomile is also known as camomile, common name of many species daisy-like plants in the family Asteraceae, used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.

Dr. Kazemian H. the lead research at the joint study said, " C. nobile may play an important role in its antibacterial activity, thus offering an additional strategy in the fight against bacterial infections. and "However, molecular investigation is required to explore the exact mechanisms of the antibacterial action and functions of this phytocompound".

Furthermore, in the testing of the effect of chamomile compounds in several models of toxicity (acute toxicity against Artemia salina and cytotoxicity against two cell lines (fibroblast and melanoma)), researchers suggested that these compounds showed low to moderate activity in all tests of acetylcholinesterase inhibitory and antibacterial activities.

And the intake of these compounds in naturally available amounts, on their own, would probably not represent a risk to human health but the possible adverse interactions with the plant matrix should not be neglected.

Therefore, people who intent to use chamomile for reduced risk and treatment of various diseases should be cautious to prevent overdoses' toxicity.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) In vivo antibacterial and wound healing activities of Roman chamomile (Chamaemelum nobile) by Kazemian H, Ghafourian S, Sadeghifard N, Badakhsh B, Heidari H1, Taji A, Shavalipour A, Mohebi R, Ebrahim-Saraie HS, Houri H, Houshmandfar R.(PubMed)
(2) Antibacterial, anti-swarming and anti-biofilm formation activities of Chamaemelum nobile against Pseudomonas aeruginosa by Kazemian H1, Ghafourian S1, Heidari H2, Amiri P3, Yamchi JK4, Shavalipour A3, Houri H3, Maleki A1, Sadeghifard N1.(PubMed)
(3) Toxic essential oils. Part III: identification and biological activity of new allylmethoxyphenyl esters from a Chamomile species (Anthemis segetalis Ten.) by Radulović NS1, Mladenović MZ, Blagojević PD, Stojanović-Radić ZZ, Ilic-Tomic T, Senerovic L, Nikodinovic-Runic J.(PubMed)

Herbal Therapy: Alfalfa, the Anti-inflammatory Natural Whole Food

Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, cultivated all over the world as hay for cattle feeding, and used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhanced digestive system, bleeding disorder, kidney and urinary tract infection, etc.
North American aboriginals have used Alfalfa seed as food in making bread and mush.

Inflammation is the natural response of immune system in regulated the production of white blood cells for protection against foreign organisms.

Alfalfa expressed significant anti-inflammatory effect through inhibited production of proinflammatory cytokins during injure, foreign invasion and free radical domino's action, etc....

According to the University of Maryland, novel pectic polysaccharide from alfalfa(Medicago sativa L.) stem, showed significant anti-inflammatory effect against mRNA expressions of the pro-inflammatory cytokine genes, especially for IL-1β antibody.

The chloroform extract of alfalfa aerial part also is found to inhibit the function of lipopolysaccharide (LPS) of Gram-negative bacteria in stimulated immune responses in induced inflammation and suppressed LPS-mediated activation of the extracellular signal-regulated the proinflammatory and prothrombotic responses of nuclear factor kappa-B pathway.

The cinnamic acid derivatives and fatty acids active constituents of the extract have also been found to be effective in ameliorated inflammation and immune response through inhibition of nitric oxide (NO), tumor necrosis factor (TNF-α), and prostaglandin E2 (PGE2) all involved in the development of inflammatory diseases.

Taking together, Alfalfa no doubt has processed an anti inflammatory effects by inhibited free radicals, proinflammatory cytokins and hormone involved the development of inflammatory and auto immune diseases.

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Structural, thermal, and anti-inflammatory properties of a novel pectic polysaccharide from alfalfa(Medicago sativa L.) stem by Chen L, Liu J, Zhang Y, Dai B, An Y, Yu LL1.(PubMed)
(2) Chloroform extract of alfalfa (Medicago sativa) inhibits lipopolysaccharide-induced inflammation by downregulating ERK/NF-κB signaling and cytokine production by Choi KC1, Hwang JM, Bang SJ, Kim BT, Kim DH, Chae M, Lee SA, Choi GJ, Kim DH, Lee JC.(PubMed)
(3) Anti-Inflammatory Activities of Cinnamomum cassiaConstituents In Vitro and In Viv by Jung-Chun Liao,1 Jeng-Shyan Deng,2 Chuan-Sung Chiu,3,4(HindaWi)

Herbal Therapy: Cinnamon - The Best Whole Food Medicine for Reduced Risk and Progression of Cognitive impairment

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
Many researchers has raised a question of their's effectiveness because of quality of the herbs due to geographic differences, time of grown and harvest, etc. I do believe that these questions can only be answered by experience herbalist.

Whole herbal medicine cinnamon may be used as functional food for treatment of cognitive impairment, a renown study suggested.

According to Hoseo University, water extracts of Cinnamomum cassia Blume bark (CCB; Lauraceae), effectively prevent the cognitive dysfunction through the prevention of formation of amyloid-β in induced cell death and toxicity.

Cognitive impairment is considered as an early stage of dementia, affecting memory, language, thinking and judgment

Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.

Administered orally of Cinnamomum zeylanicum (CZ) for a period of 21 days in animal model induced cognitive improvement through inhibition of certain extent of oxidative stress.

In AD mice model, cinnamon reduced accumulation of soluble oligomeric assemblies of β-amyloid polypeptide (Aβ) by inhibition of the formation of toxic Aβ oligoemers induced toxicity of Aβ on neuronal cells, thus reducing the risk of accumulation of plagues which is the early signed of AD development.

Also in animal study, the standardized lyophilized aqueous extract of cinnamon bark (LCZE) testing on learning and memory in rodents at 50, 100, and 200 mg/kg, p.o. dose levels against streptozotocin (STZ)-induced memory impairment, exhibited an improved discrimination between a familiar object and a novel object and function of neurotransmitters activity and reduced oxidative stress parameters in both brain parts.

Cinnamon and its chemical components may be beneficiary for patients in early state of Cognitive impairment. The use of the herbal medicine should be taken with care as overdoses may induce toxicity.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Effect of Cinnamomum zeylanicum extract on scopolamine-induced cognitive impairment and oxidative stress in rat by Jain S, Sangma T, Shukla SK, Mediratta PK.(PubMed)
(2) Agrimonia pilosa Ledeb., Cinnamomum cassia Blume, and Lonicera japonica Thunb. protect against cognitive dysfunction and energy and glucose dysregulation by reducing neuroinflammation and hippocampal insulin resistance in β-amyloid-infused rats by Park S1, Kang S1, Kim DS1, Moon BR1.(PubMed)
(3) Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models by Frydman-Marom A1, Levin A, Farfara D, Benromano T, Scherzer-Attali R, Peled S, Vassar R, Segal D, Gazit E, Frenkel D, Ovadia M.(PubMed)

Friday, 28 July 2017

Food Therapy: Kidney beans( Phaseolus), The Best Anti-Inflammatory Functional Foods

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

If you expect that herbal medicine will ease symptoms of your illness immediately, you will be disappointed. Symptoms of the diseases can only be eased gradually, depending to stage of the treatment which directly address to the cause of the disease.

Intake of kidney bean in different varieties may reduce risk and enhance treatment of inflammatory diseases, including colitis, a recent study suggested.

Kidney beans with kidney shape, strong flavor and color of reddish brown in nature are often the excellent dietary selection with no cholesterol, but a good source of protein and minerals.

According to the University of Guelph, mices fed with red and white kidney bean display a significantly anti inflammatory effects in colitis induced by dextran sodium sulphate (DSS) exposure.

The result of anti colitis activity is attributed to the potency in reduced colon tissue protein levels through ameliorated disease severity and proinflammatory mediator expression, protected further colonic damage,.....

In biochemical approaches including reporter gene assays, immunoprecipitation, kinase assays, and immunoblot analyses, ethanol extract (Pa-EE) of Phaseolus angularis was found to exert anti inflammatory effects by suppressed the release of Prostaglandin E2 (PGE(2)) and NO in Lipopolysaccharide,..........in activation of infection and inflammation.

Furthermore, the phaseolus angularis ethanol extract (Pa-EE) strongly reduced function of ipopolysaccharide in induced the mRNA expression of formation of enzymes in response to cytokines and in production of prostaglandins involved activation of infectious and inflammatory immune response.

Orally administered Pa-EE clearly decreases the ratio of ethanol/hydrogen chloride(EtOH/HCl)-induced gastritis in mice, through protection of gastric surface tissues against further damage.

In fact, the study in differentiate the efficacy of bean hull antioxidant and anti-inflammatory activities, insisted, "Anti-inflammatory activity of bean hulls was dependent on their phenolic content and antioxidant activity that were significantly affected by cultivar and extracting solvent".

Taking together, Kidney beans (Phaseolus) and their family may be used as therapeutic functional foods in improved immunomodutory activity against inflammatory diseases.

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) White and dark kidney beans reduce colonic mucosal damage and inflammation in response to dextran sodium sulfate by Monk JM1, Zhang CP1, Wu W2, Zarepoor L1, Lu JT1, Liu R2, Pauls KP3, Wood GA4, Tsao R2, Robinson LE5, Power KA6.(PubMed)
(2) Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans by Yu T1, Ahn HM, Shen T, Yoon K, Jang HJ, Lee YJ, Yang HM, Kim JH, Kim C, Han MH, Cha SH, Kim TW, Kim SY, Lee J, Cho JY.(PubMed)
(3) Antioxidant and anti-inflammatory activities of bean ( Phaseolus vulgaris L.) hulls by Oomah BD1, Corbé A, Balasubramanian P.(PubMed)

Food Therapy: Cruciferous Vegetable, the Whole Food for Lower Cholesterol Absorption through Bile Acid Binding

Recent study conducted by the University of Lund, fermented brussels sprouts, one of the member of cruciferous vegetables binded the secretion of bile acids from the liver by increased 25% of the fecal dry weight.

The study also confirmed that in various vegetables (carrots, rutabagas, peas, green beans and Brussels sprouts), total excretion of bile acids was reduced only when Brussels sprouts were added.

Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli etc.

Bile acids secreted by the liver with purpose in removing excess cholesterol in the body and aiding intestinal digestion.

Binding bile acids in gastrointestinal track is the function of preventing the reabsorption from the gut with an aim to lower the levels of cholesterol.

In vitro, the study of cruciferous vegetables also suggested that consumed regularly after steam cooking, would lower the risk of cardiovascular disease and cancer and improve public health, through lowered recirculation of bile acids resulting in utilization of cholesterol to synthesize bile acid and reduced fat absorption even more.

Dr. Kahlon TS, the lead author of the study said, " relative to cholestyramine, (a cholesterol-lowering, bileacid binding drug) in vitro bile acidbinding on dry matter basis was for the collard greens, kale, and mustard greens, 13%; broccoli, 10%; Brussels sprouts and spinach, 8%; green bell pepper, 7%; and cabbage, 5%" and (the levels of effectiveness can be classified as follow)"collardgreens = kale = mustard greens > broccoli > Brussels sprouts = spinach = green bell pepper > cabbage".

Furthermore, according to the article published in the science research, besides steam cooking showed to significantly improved bile acid binding ofgreen/leafy vegetables; sautéing also significantly improved bile acid binding of mustard greens, kale, broccoli, cabbage and green bell pepper compared with steaming, boiling or raw (uncooked).

In fact, Collard greens exhibited significantly higher bile acid binding by steaming compared with sautéing, boiling or raw in comparison to other cruciferous vegetables.

Therefore, it is safe to insist that intake of cruciferous vegetables regularly can lower the risk of cardiovascular disease and cancer, through lowering cholesterol absorption and reabsorption.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) Fermentation of vegetable fiber in the intestinal tract of rats and effects on fecal bulking and bile acid excretion by Nyman M1, Schweizer TF, Tyrén S, Reimann S, Asp NG.(PubMed)
(2) Steam cooking significantly improves in vitro bile acid binding of collard greens, kale, mustard greens, broccoli, green bell pepper, and cabbage by Kaifhlon TS1, Chiu MC, Chapman MH.(PubMed)ch
(3) In Vitro Bile Acid Binding of Mustard Greens, Kale, Broccoli, Cabbage and Green Bell Pepper Improves with Sautéing Compared with Raw or Other Methods of Preparation by Talwinder S. Kahlon, Rebecca R. Milczarek, Mei-Chin M. Chiu(Scientific Research)

Food Therapy: Asparagus, the Natural Whole Food for Neuroprotective Effects

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, because geographic differences, time of grown and harvest, etc. may effect their's potency. I do believe, these questions can only be answered by experience herbalists.

Asparagus may be a potential whole food medicine for reduced risk and treatment of neuro degenerative disease, a renowned institution suggested.

Methanol extract from Asparagus cochinchinensi, in vivo and in vitro is found to exhibit neuroprotective effects through activation of the Shp-2, antibody and ErK1/2 Akt and Akt involved the cell apoptosis, cell proliferation.

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia. Asparagus has been used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

In animal study of neurodegenerative disorders involved Alzheimer's disease (AD) , biological stresses, such as oxidative and inflammatory stress, induced neural cell damage, asparagus extract (ETAS) exerted anti neuroprotective effects, through expression of mRNAs in information transfer of DNA factors in exerted cytoprotective and anti-apoptotic functions against death of neuronal cells and early cognitive impairment.

Dr. Sakurai T, the lead researcher in the study insisted, this efficacy may be contributed by the extract in attenuated neuro-cell damage through improved hippocampus function in expression of memory.

Furthermore, other chemical compound isolated roots of Asparagus cochinchinensis may be also effective in treating cognitive impairment by ameliorated neuroinflammation through decreased production of free radical NO and suppressed microglia cells activation cause of neuronal cell death.

Taking altogether, there is no doubt that asparagus extract may be a potential agent for delay neuro degenerative disease through improved function of hippocampal regions associated with the learning and memory functions, increased neurotransmitter activity, attenuated neuro inflammatory expression and inhibited oxidative stress induced free radical in damage of neuro cells.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) The neuroprotective effects and possible mechanism of action of a methanol extract from Asparagus cochinchinensis: In vitro and in vivo studies by Jalsrai A1, Numakawa T2, Kunugi H2, Dieterich DC3, Becker A4.(PubMed)
(2) Enzyme-treated Asparagus officinalis extract shows neuroprotective effects and attenuates cognitive impairment in senescence-accelerated mice by Sakurai T, Ito T, Wakame K, Kitadate K, Arai T, Ogasawara J, Kizaki T, Sato S, Ishibashi Y, Fujiwara T, Akagawa K, Ishida H, Ohno H.(PubMed)
(3) Anti-neuroinflammatory constituents from Asparagus cochinchinensis by Jian R1, Zeng KW, Li J, Li N, Jiang Y, Tu P.(PubMed)
(4) Effect of Convolvulus pluricaulis Choisy and Asparagus racemosus Willd on learning and memory in young and old mice: a comparative evaluation by Sharma K1, Bhatnagar M, Kulkarni SK.(PubMed)

Wednesday, 26 July 2017

Food Therapy: Celery, the Natural Whole Food in Ameliorated Progression and Enhanced Treatment of Gastric Ulcer

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, because geographic differences, time of grown and harvest, etc. may effect their's potency. I do believe, these questions can only be answered by experience herbalists.

Intake of celery or supplement showed to reduce progression and treatment of gastric ulcer.

According to the King Saud University, celery [Apium graveolens L. (Apiaceae/Umbelliferae)], celery supplement at doses of 250 and 500 mg/kg body weight, enhanced the protection of gastric wall mucus (GWM), in increased stomach protection against the models used for ulcerogenesis.

Dr. Powanda MC, the lead researcher said, " Acute toxicity test revealed no deleterious or toxic symptoms or mortality over a period of 14 days. .....and (showed) a large margin of safety and "The results suggest that Apium graveolens extract significantly protects the gastric mucosa and suppresses the basal gastric secretion in rats, possibly through its antioxidant potential".

Celery is a species of Apium graveolens, belonging to the family Apiaceae, cultivated all around the globe as a vegetable. It can grow to 1/2 m tall with stalks (leaf on the top) arranging in a conical shape joined at a common base.

In support of the above analysis, celery Seed Extract (CSE), also showed to protect against and/or reduce gastric irritation caused by NSAIDs, as well as act synergistically with them to reduce inflammation without induced medication interaction of enzyme systems.

Furthermore, the methanolic extract and aqueous extracts used at 300 mg kg(-1) dose, exhibited a highly significant inhibition of gastric lesions in comparison the conventional omeprazole, in dose-dependent for both aerial part of celery.

Taking altogether, intake of celery is associated to meliorate the progression and treatment of gastric ulcer, but oral of celery supplement should be taken with care.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Celery Seed and Related Extracts with Antiarthritic, Antiulcer, and Antimicrobial Activitie by Powanda MC, Whitehouse MW, Rainsford KD.(PubMed)
(2) Over the counter (OTC) oral remedies for arthritis and rheumatism: how effective are they? by Whitehouse MW1, Roberts MS, Brooks PM.( PubMed)
(3) Antiulcerogenic and antibacterial activities of Apium graveolens essential oil and extract by Baananou S1, Bouftira I, Mahmoud A, Boukef K, Marongiu B, Boughattas NA.(PubMed)
(4) Gastric antiulcer, antisecretory and cytoprotective properties of celery (Apium graveolens) in rats by Al-Howiriny T1, Alsheikh A, Alqasoumi S, Al-Yahya M, ElTahir K, Rafatullah S.(PubMed)