Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: Massage Therapy

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).


                          The Treatment

B. Treatment in herbal and traditional Chinese medicine
B.7. Other essential alternative medicine treatment 

3. Massage Therapy
Massage therapy used in traditional Chinese medicine over thousands of year for treatment of osteoarthritis (OA)(392,321) was effective in reduced pain of mild to moderate juvenile rheumatoid arthritis through mediation of children's anxiety and stress hormone (cortisol) levels(322).
Furthermore, in a forty-two adults with rheumatoid arthritis, light pressure massage therapy improved grip strength following the first and last massage sessions, reduced pain and promoted range of motion in their wrist and large upper joints (elbows and shoulders) by the end of the one month period(324).

Dr. Field T said," Moderate pressure massage,....increased weight gain in preterm infants, reduced pain in different syndromes including fibromyalgia and rheumatoid arthritis, enhanced attentiveness, reduced depression and enhanced immune function (increased natural killer cells and natural killer cell activity).......(as well as) reduced depression, anxiety and heart rate, ...... increased vagal activity and decreased cortisol levels"(323)

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)

(321)

(322) Juvenile rheumatoid arthritis: benefits from massage therapy by Field T1, Hernandez-Reif M, Seligman S, Krasnegor J, Sunshine W, Rivas-Chacon R, Schanberg S, Kuhn C.(PubMed)

(323) Massage therapy research review by Field T1.(PubMed)

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: Acupuncture

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).


                          The Treatment

B. Treatment in herbal and traditional Chinese medicine
B.7. Other essential alternative medicine treatment 

2. Acupuncture
The most oldest form of medical treatment in traditional Chinese medicine has been known for its function in relief pain(383,313) and functional limitation(384,314) for chronic patient, including patient with moderate or severe chronic pain(383,313).
The Cochrane Field of Rehabilitation and Related Therapies and the Cochrane Musculoskeletal Review suggests the effectiveness of acupuncture as a rehabilitation of an adjunct therapy for the symptomatic treatment of rheumatoid arthritis showed to reduce symptomatic knee pain in patients with RA 24 hours and 4 months post treatment(315). According to Dr. Wang C and the research team at the Tufts Medical Center and Tufts University School of Medicine, acupuncture showed to decrease pain, significant reduced morning stiffness and inflammatory markers in comparison to controls in patients with rheumatoid arthritis(316).

In a total of 80 eligible patients, 36 patients with mean age of 58 study, electroacupuncture (EA) and traditional Chinese acupuncture (TCA) significantly reduced tender joints and improved physician's and patients global score but large scale trial are recommended in orderto clarify the existing evidence base on acupuncture for RA.(317).

In the discuss of the imbalance between T-helper 17 (Th17) cells and regulatory T (Treg) cells induced rheumatoid arthritis, use of electroacupuncture (EA) not only restores the balance of Th17/Treg cell but also expresses its anti-inflammatory effects through educed paw volumes, arthritis scores and inflammation scores(319) in collagen-induced arthritis (autoimmune disease ) rats(320).

In fact, poor quality of studies and conflicting evidence exists in placebo-controlled trials, in some cases are also found to accompany with certain inconsistency of its efficacy(318).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)

(313)
(314)
(315) Acupuncture and electroacupuncture for the treatment of rheumatoid arthritis by Casimiro L1, Barnsley L, Brosseau L, Milne S, Robinson VA, Tugwell P, Wells G.(PubMed)
(316) Acupuncture for pain relief in patients with rheumatoid arthritis: a systematic review by Wang C1, de Pablo P, Chen X, Schmid C, McAlindon T.(PubMed)
(317)Acupuncture in the treatment of rheumatoid arthritis: a double-blind controlled pilot study.
Tam LS1, Leung PC, Li TK, Zhang L, Li EK.(PubMed)

(318) A pilot study of acupuncture as adjunctive treatment of rheumatoid arthritis by Zanette Sde A1, Born IG, Brenol JC, Xavier RM.(PubMed)

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: Ice or Heat Therapies

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).


                          The Treatment

B. Treatment in herbal and traditional Chinese medicine
B.7. Other essential alternative medicine treatment 

Beside suggesting certain herbal medicine for treatment of osteoarthritis, modern herbal and TCM medicine doctors may also combine other natural treatment for alleviating symptoms of the disease

1. Ice or Heat Therapies
1.1. Ice therapy
Ice therapy, using the techniques of compression and elevation basic principles for treatment of acute soft tissue injury, if applied correctly with repeated application of 10 minutes for avoiding side effects, and preventing possible further injury(306). According to Dr. van den Bekerom MP and the research team at the Orthopaedic Research Center Amsterdam, treatment of pain, swelling, ankle mobility or range of motion, must be made on an individual basis, carefully weighing the relative benefits and risks of each option, and must be based on expert opinions and national guidelines(307).
Unfortunately, according to the study of University of Ottawa, thermotherapy, including hot and ice packs application is found a significant effects on arthritic hands of patient with rheumatoid arthritis and most studies(308).

1.2. Heat therapy
Heat therapy, is another form of thermotherapy with the use of heat in therapy for pain relief by alternative rehabilitation specialists. The review of studied that met the criteria of 328 subjects, by the University of Ottawa, superficial moist heat is found effective for relieved joint swelling, pain, reduced medication intake, improved range of motion (ROM), grip strength, hand function but limited by methodological considerations such as the poor quality of trials(309).  In support of the above, the research team lead by Dr.  found that in 17 with symmetrical rheumatoid arthritis (RA) applied heat to 1 hand twice daily for 2 years, heat therapy improve joint swelling, joint tenderness and grip strength with daily heat therapy did not accelerate the proliferative lesion in RA(310).

In regard of thermotherapy used of heat and cold treatment, Dr. Oosterveld FG and Dr. Rasker JJ said,s" In general, locally applied heat increases and locally applied cold decreases the temperature of the skin, superficial and deeper tissues, and joint cavity. Most studies dealing with the effects of heat and cold on pain, joint stiffness, grip strength, and joint function in inflamed joints report beneficial effects" and " In vitro studies show that higher temperatures increase the breakdown of articular cartilage and tissues that contain collagen".(311)

And according to the traditional Chinese medicine, correlation between cold and hot pattern are related to different pathways, and the network of that might be used for identifying the pattern and classification in other diseases including subsets of RA(312).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)

(306) Ice therapy: how good is the evidence? by Mac Auley DC1.(PubMed)
(307) What is the evidence for rest, ice, compression, and elevation therapy in the treatment of ankle sprains in adults? by van den Bekerom MP1, Struijs PA, Blankevoort L, Welling L, van Dijk CN, Kerkhoffs GM.(PubMed)
(308) Thermotherapy for treating rheumatoid arthritis by Robinson V1, Brosseau L, Casimiro L, Judd M, Shea B, Wells G, Tugwell P.(PubMed)(309) Thermotherapy for treating rheumatoid arthritis by Welch V1, Brosseau L, Shea B, McGowan J, Wells G, Tugwell P.(PubMed)
(310) Rheumatoid arthritis: failure of daily heat therapy to affect its progression by Mainardi CL, Walter JM, Spiegel PK, Goldkamp OG, Harris ED Jr.(PubMed)
(311) Treating arthritis with locally applied heat or cold by Oosterveld FG1, Rasker JJ.(PubMed)

(312) Correlation between cold and hot pattern in traditional Chinese medicine and gene expression profiles inrheumatoid arthritis by Jiang M1, Xiao C, Chen G, Lu C, Zha Q, Yan X, Kong W, Xu S, Ju D, Xu P, Zou Y, Lu A.(PubMed)

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: The alternative Electrostimulation

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).


                          The Treatment

B. Treatment in herbal and traditional Chinese medicine

B.6. The alternative Electrostimulation
Electrostimulation has been applied to acupuncture to treat pain associate to the clips from the therapeutic device, are attached to the needles. This type of alternative application also was found in Ancient Egyptians and later the Greeks and Romans, dates back to thousands of years BC for treatment of pain, muscle dysfunction and sarcopenia(303).
Dr. Men'shikova IV. in the comment of combination of modern physiotherapeutic methods in rehabilitation said,"(Use of electrostimulation of smooth muscle) All patients(with RA) reported alleviation of pain and oedema in the affected joint. The rehabilitation period was 2-5 days shorter than after the traditional treatment(304).

In support to the above study, the School of Rehabilitation Sciences, University of Ottawa, in the review of randomized controlled trials (RCTs) and controlled clinical trials (CCTs), case-control and cohort studies comparing ES against placebo or another active intervention in patients with RA showed that electrostimulation (ES) was shown to have a clinically beneficial effect on grip strength and fatigue resistance for RA patients with muscle atrophy of the hand but the evidences were limited due to low methodological quality of the trial included(305).


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)

(303) Neuromuscular electrostimulation techniques: historical aspects and current possibilities in treatment of pain and muscle waisting by Heidland A1, Fazeli G, Klassen A, Sebekova K, Hennemann H, Bahner U, Di Iorio B.(PubMed)

(304) [Combination of modern physiotherapeutic methods in rehabilitation of patients with osteoarthrosis andrheumatoid arthritis after arthroscopic surgery on the knee joint].[Article in Russian] by Men'shikova IV.(PubMed)

(305) Electrical stimulation for the treatment of rheumatoid arthritis by Brosseau LU1, Pelland LU, Casimiro LY, Robinson VI, Tugwell PE, Wells GE.(PubMed)

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: The Miracle Topical Remedy

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).


                          The Treatment

B. Treatment in herbal and traditional Chinese medicine

B.5. The Miracle Topical Remedy
Certain topical remedies used in traditional or folk medicine have found effective on attenuate persistent symptoms of rheumatoid arthritis

1. Capsaicin cream

Topical Capsaicin cream used for treatment of soft tissue with a pharmaceutical name of Finalgon®(420), has been shown effectively to reduced symptoms of pain  of  80% of patient with rheumatoid arthritis in a double-blind randomized study, 70 patients with osteoarthritis (OA) and 31 with rheumatoid arthritis (RA)(301a). Dr. Rumsfield JA and Dr. West DP. Said," Although capsaicin is clinically used as an external analgesic for temporary relief of neuralgia, it has also been widely used as a research tool to study peripheral pain"(302). of that may be reason for the topical is recommended for treatment in patient with RA in modern herbal and TCM practitioners.

2. Avocado soybean unsaponifiables (ASU)

 Avocado soybean unsaponifiables (ASU) is a natural vegetable extract composed of  one-third avocado oil and two-thirds soybean oil, may be used effectively for treatment of knee osteoarthritis to replace the use of analgesics and nonsteroidal antiinflammatory drugs (NSAIDs), according to the a three-month, prospective, randomized, double-blind, placebo-controlled, parallel-group trial(372,294)).

In rat model, administration of avocado/soybean unsaponifiable (ASU), reduced bone resorption, expression of TRAP and RANKL through its positive effect on bone repair following ligature-induced periodontitis(295). Dr. Pirotta M said," Despite support for some of the most popular CAM therapies for pain from arthritis-related conditions, additional high quality research is needed for other therapies, especially for herbals and homeopathy"(296).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)

(294)

(295) Effect of avocado/soybean unsaponifiables on ligature-induced bone loss and bone repair after ligature removal in rats by Oliveira GJ1, Paula LG1, Souza JA1, Spin-Neto R2, Stavropoulos A3, Marcantonio RA1.(PubMed)

(296) Selected CAM therapies for arthritis-related pain: the evidence from systematic reviews by Soeken KL1.(PubMed)

(301a) Treatment of arthritis with topical capsaicin: a double-blind trial by Deal CL1, Schnitzer TJ, Lipstein E, Seibold JR, Stevens RM, Levy MD, Albert D, Renold F.(PubMed)

(302) Topical capsaicin in dermatologic and peripheral pain disorders by Rumsfield JA1, West DP.(PubMed)

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: The Important supplements

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).


                          The Treatment

B. Treatment in herbal and traditional Chinese medicine

B.4. The Important supplements for rheumatoid arthritis
1. Glucosamine
Glucosamine, a compound of the simple sugar glucose and the amino acid glutamine, is a precursor for glycosaminoglycans(194,289), a major component of joint cartilage(195,290). In a randomized placebo-controlled study of 51 rheumatoid arthritis (RA) patients: 25 patients in the glucosamine group and 26 patients in the placebo group, Glucosamine hydrochloride at a daily dose of 1,500 mg showed to improve some symptomatic effects on RA(291).
The orally administered combination of a glucosamine-chondroitin-quercetin glucoside (GCQG) supplement also exerted a special effect on improving the synovial fluid properties in OA patients, according to the Matsuno Clinic for Rheumatic Diseases(292). Furthermore, a novel glucosamine analogue also showed to inhibit the development of RA through exerting antioxidative and immunomodulatory effects(293).

2. Omega 3 fatty acids

Omega-3 fatty acids found abundantly in cold water fish, algae and seeds and nuts of plant has shown to exhibit the prevention of different pathologies, such as cardiovascular, psychiatric, neurological, dermatological and rheumatological disorders(297), including RA. Dr. Shafaghat A said," The hexane extract from the flower, leaf, stem, and seed contained 39.1%, 43.2%, 29.0%, and 37.6% of omega-3 fatty acids, ... possess considerable antioxidant activity(298) of that may be helpful in attenuate the oxidative stress in induction of RA.

Dr. Jeromson S. and the research team at the University of Stirling suggested that Omega 3 fatty acid also plays an essential role in Skeletal Muscle Health(299) in inhibition of pro inflammatory cytokines(300) which has a direct influence to the onset of rheumatoid arthritis.

In Rheumatoid Arthritis, omega-3 fatty acid supplementation improved physical functioning, physical role, bodily pain, general health, vitality, social functioning, grip strength, morning stiffness,....in comparison to the effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs) in patient of rheumatoid arthritis(301).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)

(289)

(290)

(291) Effects of glucosamine administration on patients with rheumatoid arthritis by Nakamura H1, Masuko K, Yudoh K, Kato T, Kamada T, Kawahara T.(PubMed)

(292) Effects of an oral administration of glucosamine-chondroitin-quercetin glucoside on the synovial fluid properties in patients with osteoarthritis and rheumatoid arthritis by Matsuno H1, Nakamura H, Katayama K, Hayashi S, Kano S, Yudoh K, Kiso Y.(PubMed)

(293) The anti-arthritic and immune-modulatory effects of NHAG: a novel glucosamine analogue in adjuvant-inducedarthritis by Shah SU1, Jawed H, Awan SI, Anjum S, Simjee SU.(PubMed)

(294)

(295) Effect of avocado/soybean unsaponifiables on ligature-induced bone loss and bone repair after ligature removal in rats by Oliveira GJ1, Paula LG1, Souza JA1, Spin-Neto R2, Stavropoulos A3, Marcantonio RA1.(PubMed)

(296) Selected CAM therapies for arthritis-related pain: the evidence from systematic reviews by Soeken KL1.(PubMed)

(297) Omega-3 fatty acids and antioxidants in neurological and psychiatric diseases: an overview. by Mazza M1, Pomponi M, Janiri L, Bria P, Mazza S.(PubMed)

(298) Antioxidant, antimicrobial activities and fatty acid components of flower, leaf, stem and seed of Hypericum scabrum by Shafaghat A1(PubMed)

(299) Omega-3 Fatty Acids and Skeletal Muscle Health by Jeromson S1, Gallagher IJ2, Galloway SD3, Hamilton DL4(PubMed)

(300) [Effects of lymphatic drainage and omega-3 polyunsaturated fatty acids on intestinal ischemia-reperfusion injury in rats].[Article in Chinese] by Zhou KG1, He GZ, Zhang R, Chen XF(PubMed)

(301) Role of omega-3 fatty acid supplementation with indomethacin in suppression of disease activity in rheumatoid arthritis by Das Gupta AB1, Hossain AK, Islam MH, Dey SR, Khan AL.(PubMed)

Most Common Disease of elder: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Rheumatoid Arthritis: The Top Minerals according to Herbal and TCM medicine

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                      Rheumatoid Arthritis

Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).


                          The Treatment

B. Treatment in herbal and traditional Chinese medicine
B.3. The Preventive Minerals and Vitamins
1. Minerals for Immunity
Strengthen immunity plays an important role in regulating the free radical and other form of irregular cell growth causes of inflammation and auto immune diseases as well as attenuating the foreigner invasion. According to the study maintaining normal levels of  Copper, Selenium and Zinc have found to improve immune function against morbidity, decrease antibody production, infection, impaired natural killing cells, etc......(252) in animal study. Also according to Dr. Kremer JM and Bigaouette J., deficiency of pyridoxine, zinc, copper, and magnesium may induce rheumatoid arthritis expression(253).

1.1. Copper
Epidemiological studies suggested that levels of copper may be influence to the risk of rheumatoid arthritis has produced inconclusive results, it probably due to the disease orgination(254)(255). According to the relevant published data were retrieved through PubMed, Chinese National Knowledge Infrastructure (CNKI), and Chinese Biomedical Database (CBM) before September 20, 2014 of 1444 RA cases and 1241 healthy controls, above normal serum levels of copper (Cu) has found in patients with rheumatoid arthritis(254). Dr Li J and the research team at the joint study lead by Sichuan University, suggested patient with rheumatoid arthritis with B-lymphocyte dysfunction are associated to lower levels of copper, selenium and zinc levels(255). Other study insisted that the alternation of copper concentration may be a result of the changes of the immunoregulatory cytokines(256). Dr Percival SS said,"The immune system requires copper to perform several functions,.....interleukin 2 is reduced and T cell proliferation are reduced in copper deficiency"(257).

1.2. Magnesium
Dr. Minton K. in the study of mutation of Mutation of the magnesium transporter 1 (MAGT1) gene has been found to associate to immunodeficiency due to reduced levels of magnesium(258), inducing severe chronic viral infections and inflammations(259). Deficiency of magnesium is found in patient with RA(253), routine dietary supplementation with multivitamins and trace elements is appropriate in this population(253), Dr. Kremer JM1, Bigaouette J. suggested. The Ankara University study expressed only slight and statistically insignificant reductions of plasma and erythrocyte Mg levels of the RA patients showed when compared to controls, with a positive correlations between erythrocyte SOD activity and Mg level(260).

1.3. Selenium
Selenium, is found to be one of most powerful antioxidant in enhancing immune system in fighting against inflammatory and immune-related diseases, including anti-viral immunity, autoimmunity, sepsis, allergic asthma, and chronic inflammatory disorders mainly through its incorporation into selenoproteins(261). Low serum Se concentration is found to associate in patient with RA(262). But according to the Free University of Brussels, in a in a double blind multi-centric placebo-controlled study showed no clinical benefit selenium treatment on RA but a significant  improvement in arm movements and health feeling(263).

1.4. Zinc
Recent study showed that lower than normal serum levels of Zinc (Cu) has found in patients with rheumatoid arthritis(254).

Deficiency of zinc is found to increase immune response through activation of increasing immune cell and inducing  pro inflammatory ccytokines IL6(264), especially in aging population(265). who are vulnerable for the aging degenerative chronic diseases of rheumatoid arthritis(266).

1.5. Pyridoxine
Dietary pyridoxine showed to improve immune responses(267) and reduced the expression of pro inflammatory cytokines of that may relate to the early onset of rheomatoid arthritis(268) but the deficiency was not severe enough to affect the immune system, according to the Instituto Nacional de Ciencias Médicas y Nutricion(269). Dr Chiang EP. and the research team of the National Chung-Hsing University said, " Suboptimal vitamin B6 status seen in rheumatoid arthritis can be corrected by 50 mg pyridoxine supplementation for 30 days,.... but (The pyridoxine supplementation) did not suppress pro-inflammatory cytokine production in patients with rheumatoid arthritis"(270).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(252) Trace Minerals and Immunity in Beef Cattle by SQM

(253) Nutrient intake of patients with rheumatoid arthritis is deficient in pyridoxine, zinc, copper, and magnesium by Kremer JM1, Bigaouette J.(PubMed)

(254) Serum Levels of Copper and Zinc in Patients with Rheumatoid Arthritis: a Meta-analysis. by Xin L1, Yang X1, Cai G1, Fan D1, Xia Q1, Liu L1, Hu Y1, Ding N1, Xu S2, Wang L1, Li X1, Zou Y1, Pan F3.(PubMed)

(255) Effects of B-lymphocyte dysfunction on the serum copper, selenium and zinc levels of rheumatoid arthritispatients by Li J1, Liang Y2, Mao H3, Deng W4, Zhang J5.(PubMed)

(256) Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritisand osteoarthritis by Yazar M1, Sarban S, Kocyigit A, Isikan UE.(PubMed)

(257) Copper and immunity by Percival SS1(PubMed)

(258) Magnesium regulates antiviral immunity by Kirsty Minton(PubMed)

(259) MAGT1 by Genetic home reference

(260) Trace element and magnesium levels and superoxide dismutase activity in rheumatoid arthritis by Tuncer S1, Kamanli A, Akçil E, Kavas GO, Seçkin B, Atay MB.(PubMed)

(261) The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities by Huang Z1, Rose AH, Hoffmann PR.(PubMed)

(262) The Association Between Serum Selenium Levels with Rheumatoid Arthritis by Yu N1, Han F1, Lin X1, Tang C1, Ye J1, Cai X2.(PubMed)

(263) Selenium supplementation in rheumatoid arthritis investigated in a double blind, placebo-controlled trial by Peretz A1, Siderova V, Nève J.(PubMed)

(264) Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation by Wong CP1, Rinaldi NA, Ho E.(PubMed)

(265) Zinc and inflammatory/immune response in aging by Vasto S1, Mocchegiani E, Malavolta M, Cuppari I, Listì F, Nuzzo D, Ditta V, Candore G, Caruso C.(PubMed)

(266) Zinc and its role in immunity and inflammation by Bonaventura P1, Benedetti G1, Albarède F2, Miossec P3.(PubMed)

(267) Effects of dietary pyridoxine on immune responses in abalone, Haliotis discus hannai Ino by Chen H1, Mai K, Zhang W, Liufu Z, Xu W, Tan B.(PubMed)

(268) High dose dietary pyridoxine induces T-helper type 1 polarization and decreases contact hypersensitivity response to fluorescein isothiocyanate in mice by Kobayashi C1, Kurohane K, Imai Y.(PubMed)

(269) Biochemical deficiency of pyridoxine does not affect interleukin-2 production of lymphocytes from patients with Sjögren's syndrome by Tovar AR1, Gómez E, Bourges H, Ortíz V, Kraus A, Torres N.(PubMed)

(270) Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients withrheumatoid arthritis by Chiang EP1, Selhub J, Bagley PJ, Dallal G, Roubenoff R.(PubMed)