Holistic Health Articles and Research Related to Herbal Medicines, Foods and Phytochemicals

Tuesday, 24 February 2015

Quick and Easy Healthy Kid Loved Lunch Box Recipe: Mac & cheese, all dress up

Posted Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

All natural macaroni and cheese 1 package (6 oz./ 185 g)
Cheddar, monterey jack, or havarti cheese 1/2 cup (2 oz./60 g) shredded
Parmesan cheese 2 tablespoons, grated
Frozen vegetables such as peas, carrots, shelled edamame, and/or broccoli florets 1 cup (5 oz, 155 g).

Prepare the macaroni and cheese sauce according to the package directions. Stir in the extra cheeses and the vegetables. Cook gently over low heat until the cheese is melt and the vegetable are heated through, about 5 minutes.
Spoon servings into insulated containers as needed and closed tightly to keep warm. Don't forget to pack a fork! ( Let any remaining pasta cool, then cover tightly and refrigerate for up to 5 days).

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Monday, 23 February 2015

(!st edited) Most Common Diseases of Ages of Elders: Upper gastrointestinal disorders: Gastric ulcers - Preventions, Treatments and Management

Gastric ulcer, a type of peptic ulcer is a condition of a localized tissue erosion in the lining the stomach.

A. Symptoms
1. Abdominal pain, bloating, septic shock
A clinical, retrospective, cross-sectional and descriptive study of patients who were treated at the General Hospital of Mexico with a diagnosis of perforated peptic ulcer from January 2006 to December 2008 of 30 patients with an average age of 57.07 years (± 14.2 years), most common symptoms include
1. Abdominal pain prior to admission,
2. Bloating,
3. Septic shock(1).

2. Dyspepsia
Dyspepsia, may be the first symptoms of peptic ulcer disease (an ulcer of the stomach or duodenum), is the medical term for difficult digestion, including various symptoms in the upper abdomen, such as fullness, discomfort, early satiation, bloating, heartburn, belching, nausea, vomiting, or pain(2).

3. Blood in stool
As a result of upper gastrointestinal bleeding(4).

4. Nausea and vomiting
Upper gastrointestinal tract with gastric erosions and duodenal ulcers in most cases can cause nausea and vomiting(3).

5. Dizziness and tarry stools
Patients with bleeding from a gastric ulcer, and endoscopic hemostasis may consist symptoms of with dizziness and tarry stools, depending to amounts of blood loss(4)

5. Unintentional weight loss
Benign gastro-colic fistula with symptoms of worsening abdominal pain, nausea, vomiting, diarrhea and weight loss, is a rare occurrence due to the progress in medical management of gastric ulcer disease(5).

6. Mood disorders
Individuals with chronic fatigue syndrome, fibromyalgia, bowel disorder or stomach or intestinal ulcers had the highest risk of mood disorders(6).
7. Etc.

B. Causes and Risk factors
B.1. Causes
1. Imbalance between stomach acid and upper GI tract mucosa
Imbalance between stomach acid, a common conditions impacted quality of life for a significant number of people nationwide. is the leading cause of Gastric ulcer, due to an abnormal secretion by gastric parietal cells and the ability of upper GI tract mucosa(7).

2. Medication
Medication such as aspirin and Non-steroidal anti-inflammatory drugs (NSAIDs) may cause damage of the gastrointestinal tract and aggravate pre-existing diseases. Risk of bleeding is increased with advancing age, presence of Helicobacter pylori(HP), previous history of bleeding, anticoagulant use, etc.(9).

3. Helicobacter pylori and chronic gastritis
Helicobacter pylori, a Gram-negative, microaerophilic bacterium found in the stomach, has shown to be a leading cause of idiopathic peptic ulcers in developed countries, especially, the bacterial now exhibited an increase in antibiotic resistance(10).
Higher degree of HP colonisation in gastric mucosa showed to associate to the persistence of active ulcer (GU+) and its infection is a leading cause of the development and chronicity of peptic GU disease(11).
4. Etc.

B.2. Risk factors
1. Periodontal disease
according to the study of eligible 28 765 subjects, the rate of periodontitis in people with peptic ulcer(1.4%) is 20% plus(8).

2. Aging
According Osaka City University Graduate School of Medicine, risk of gastric ulcer, especially corpus-predominant atrophic gastritis increases proportionally with increased life expectancy(12).

3. Smoking
Cigarette smoking increases xanthine oxidase activity, leukotrienes, and nitric oxide production and also neutrophil infiltration in the gastric mucosa(13).

4. Mechanical ventilation
Mechanical ventilation increases risk for bleeding in the upper part of the gastrointestinal tract. Patients recieved pantoprazole and famotidine are associated to bleeding in the upper part of the gastrointestinal tract14).

5. Critical illness
Critical illness such as ischemia can lead to back-diffusion of H+ ions may impair mucosal buffering that can lead to intramural acidosis and cell death(15).

8. Etc.

C. Complications
1. Death
according to 701 patients with gastric ulcers admitted to hospital within the period 1955-64, 180 died within a five-year period with causes of death of autopsy of 66%(16).

2. Peptic ulcer bleeding
Peptic ulcer bleeding is a frequent and dramatic event with both a high mortality rate associated to increased risk of in individuals aged>65 years and increasing further in those aged>75 years, especially in those with co-morbidities(17).

3. Perforative hole
Perforated gastroduodenal ulcers, in many cases, can lead to perforative hole in 11.7% of the patients(18).

4. Others
According to, Ataturk University
4.1. Giant ulcers are more prone to severe hemorrhage and malignancy
4.2. Giant gastric ulcers are more prone to free perforation(19).
Other complications may include
4.3. Hematemesis, hematochezia and perforation(20).

D. The do and do not’s list
1. Dietary phytosterols and phospholipids
Experiments using animal peptic ulcer models showed that intake of lipid fraction in foods from the staple diets not only reduced risk if adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs in both gastric and duodenal ulceration patients, but also promoted healing of ulceration.
due to phospholipid, sterol and sterol ester fractions of the lipid present in the diets. including phosphatidyl ethanolamine (cephalin) and phosphatidyl choline (Lecithin), β-sitosterol, etc.(21).

2. Reduce intake of NSAID if possible
As NSAID has been proven to cause gastric Ulcer(9), by by inhibiting the body’s production of prostaglandins, hormones that protect the stomach lining.

3. Smoking
Cigarette smoking induce gastric ulcer due to the presence of increased xanthine oxidase activity, leukotrienes, and nitric oxide production and neutrophil infiltration in the gastric mucosa(13).

4. Don’t miss your dental appointment
Periodontitis is more frequently occurred in elder patients. Risk of gastric ulcer increases proportionally with existence of teeth loss and bad oral hygiene(8).

5. Reduce stress
The risk of gastrointestinal diseases has found to increase with psychosocial stress by 1.5 times, including hemorrhagic ulcers, gastric ulcer/duodenal ulcer, non-H. pylori and non-NSAID ulcers etc.(22).

6. Excessive hard liquor drinking can damage the lining of stomach and worsen ulcers and induced pain, through its interference of gastric acid secretion and activity of the muscles surrounding the stomach.(22a).

7. According to the article of Good Foods / Bad Foods For Peptic Ulcers By Sharon Gillson, she suggested the below

Restrict or avoid those foods that may cause irritation to the digestive system
Reduce excessive acid production
Prevent unpleasant side effects, such as heartburn.
Eat 5 to 6 small meals a day instead of 3 larger meals. It is important that you avoid overeating. Frequent, smaller meals will be more comfortable and easier on the stomach than two or three large meals a day.
Eat a diet rich in fiber, especially from fruits and vegetables
Rest and relax a few minutes before and after each meal, as well as remaining relaxed during meals.
Eat slowly and chew you food well
Avoid eating within 3 hours before bedtime
Eat foods that are low fat
Avoid foods that are fried
Avoid foods that are spicy
Cut down on the following foods:
- Coffee
- Decaffeinated coffee
- Tea
- Cola drinks
- Carbonated beverages
- Citrus fruits
- Tomato-based products
- Chocolate(23)

F. Diagnosis If you are experience the symptoms of gastric ulcer as mentioned above, a complete physical examination (rectal exam) and and medical (weight loss or fatigue, present and past medication use including chronic use of NSAID) and family history( If your family has a history of gastric ulcer) should be recorded to rule out other diseases with the same symptoms (Gallstones, heart condiction, GERB, etc.)
F1. Non invasive testing
1. Blood test (Complete blood count)
The aim of the test is to check for the abnormally high or low counts which may be an indication of infection.

2. Fecal occult blood test (FOBT)
The aim of test to check for hidden (occult) blood in the stool (feces) with an aim to detect subtle blood loss in the gastrointestinal tract.

3. Screen for Helicobacter pylori test
If your doctor suspects that you have gastric ulcer due to infection, screen for Helicobacter pylori test may be ordered, including Blood antibody test, Stool antigen test, Urea breath test, etc.)

4. Endoscopy
Endoscopy is a procedure for your doctor look inside your body with an endoscope, (a long, thin tube equipped with a tiny video camera) to detect any abnormality including the presence of peptic ulcers, bleeding, stomach cancer, etc.
5. Biopsy
In biopsy, a sampling of tissues is withdrawn for examination.
6. Etc.

F. Treatments
F1. In conventional medicine perspective
1. Antibiotics
Although antibiotics have shown to be best treatment for gastric ulcer caused by H. pylori, unfortunately, monoresistant strains are prevalent with high rates(34).

2. Sequential and Conventional triple therapies
Most frequently used in treatment of gastric ulcer, Sequential and Conventional triple therapies
showed overall eradication rate of 81.0%, and 75.7%(35).

3. Endoscopy
Endoscopy in most cases is used to control ulcer bleeding, but has low benefits for patients with benign ulcer in comparison to its cost(36).

4. Probiotic therapy
Probiotic treatment with an aim to reduce fungal colonization and on patients with gastric ulcer (GU) and ulcerative colitis (UC), showed effectively in delay process of fungal colonization, reduced inflammation and promoted healing of GI tract(37).

3. Surgery
Surgery will always be the last resources for treatment gastric ulcer, and only be performed if patients do not respond to medicines or endoscopy
1.Vagotomy
The aim of the surgery is to control the secretion of stomach acid by cutting of the vagus nerve.

2. Pyloroplasty
Pyloroplasty is a surgical procedure used to widen the opening in the lower part of the stomach (pylorus), to allow stomach contents to empty more quickly into the intestine.

3. Partial gastrectomy
Partial gastrectomy is a surgical procedure removed parts of the stomach, but vagotomy( a surgical procedure involved resection of the vagus nerve) and pyloroplasty(a surgical procedure involved removal of lower portion of the stomach,) have not yet been established as a routine treatment for all gastric ulcers(38).

B. Herbs
1. Deglycyrrhizinated licorice
B. Herbs
1. Deglycyrrhizinated licorice
Deglycyrrhizinated licorice used to treat people with gastric and peptic ulcers for nearly a hundred years, showed to increase the content of endogenous prostaglandins in the gastric mucosa, due to endogenous secretin released by its antiulcer agents, namely FM 100, plaunotol, and teprenon(39)(40).

2. Aloe Vera
According to the article of “Effect Of Orally Consumed Aloe Vera Juice On Gastrointestinal Function In Normal Humans, excerpts By Jeffrey Bland, Ph.D., aloe vera juice promoted proper gastrointestinal function, probably through its regulated gastrointestinal pH, improved
gastrointestinal motility, increased stool specific gravity, and reduced populations of certain fecal micro-organisms activities(41).

3. Mastic gum
According to the article of "Strategies to Protect Against Potential Bone-Destroying Effects”By Chris D. Meletis, ND, the author, mastic gum only supports the health of patients with ulcers and also inhibits the bacteria H. pylori(42).

4. Ginger
Ginger used for thousands of years to enhance the function of digestive system to treat stomach distress including nausea, vomiting, diarrhea and in digestion, acid reflux, motion sickness, dyspepsia, etc., its methanol extract showed to inhibit the growth of all 19 strains in vitro, probably through its anti-inflammatory, antimicrobial and analgesic activities(43)

5. Peppermint
In vitro, has significant Animal model studies, peppermint demonstrate a relaxation effect on gastrointestinal (GI) tissue, probably through its antimicrobial and antiviral activities, strong antioxidant and antitumor actions, and some antiallergenic potential.analgesic and anesthetic effects, but caution is necessary for the use of peppermint therapy due to absent and limited clinical trials(44).
6. Etc.

F.3. In traditional Chinese medicine perspective
1. Acupuncture and moxibustion
According to chief physician YANG Mei-liang, a famous doctor of TCM in China, applying spleen and stomach theory with the use of acupuncture and moxibustion together with accurate and proper prescription association and acupuncture point selection, is the most effective way in treating patients with insomnia, ophthalmopathy, intestinal obstruction, gastric ulcer, etc.(45).

2. Adlay seeds
Adlay seeds used to treat warts, chapped skin, rheumatism, and neuralgia in traditional Chinese medicine (TCM), showed to inhibit antiulcer activity, probably through anti oxidative and inflammatory properties(46).

3. Qifang Weitong Powder and omeprazole
Qifang Weitong Powder combined with omeprazole (QWP-Op), showed to improve the histological quality of ulcer healing and restore the morphological structure of gastric mucosa in patients with active gastric ulcer(47).

4. Kangyanling and Omeprazole
Combined therapy with Kangyanling (KYL, a Chinese herbal preparation) and Omeprazole on post-burn digestive dysfunction, showed to restore normal pH value in gastric mucosa(48)

5. Jianpi Qingre Huayu Recipe
Jianpi Qingre Huayu Recipe showed to cure gastric ulcer up to 86.7% in 30 patients with gastric ulcer of Pi -insufficiency and stasis-heat syndrome type(49).

6. Jianwei Yuyang Granule
According to the study by Institute of Integrative Traditional Chinese and Western Medicine, Xiangya Hospital of Central South University, Jianwei Yuyang Granule with its good clinical compliance, has favorable effects in relieving clinical symptoms, promoting endoscopic ulcer healing and HP clearance, etc.(50).

References
(1) http://www.ncbi.nlm.nih.gov/pubmed/21631975
(2) http://www.ncbi.nlm.nih.gov/pubmed/22327302
(3) http://www.ncbi.nlm.nih.gov/pubmed/23152072
(4) http://www.ncbi.nlm.nih.gov/pubmed/22187712
(5) http://www.ncbi.nlm.nih.gov/pubmed/21756322
(6) http://www.ncbi.nlm.nih.gov/pubmed/18625088
(7) http://www.ncbi.nlm.nih.gov/pubmed/11729446.
(8) http://www.ncbi.nlm.nih.gov/pubmed/22980150
(9) http://www.ncbi.nlm.nih.gov/pubmed/23163547
(10) http://www.ncbi.nlm.nih.gov/pubmed/23018004.
(11) http://www.ncbi.nlm.nih.gov/pubmed/1759132
(12) http://www.ncbi.nlm.nih.gov/pubmed/21061517
(13) http://www.ncbi.nlm.nih.gov/pubmed/9872502
(14) http://www.ncbi.nlm.nih.gov/pubmed/18310651
(15) http://www.ncbi.nlm.nih.gov/pubmed/7495942
(16) http://www.ncbi.nlm.nih.gov/pubmed/1211040
(17) http://www.ncbi.nlm.nih.gov/pubmed/17896831
(18) http://www.ncbi.nlm.nih.gov/pubmed/1881067
(19) http://www.ncbi.nlm.nih.gov/pubmed/1636903
(20) http://www.ncbi.nlm.nih.gov/pubmed/9059054
(34) http://www.ncbi.nlm.nih.gov/pubmed/22611319
(35) http://www.ncbi.nlm.nih.gov/pubmed/22654429
(36) http://www.ncbi.nlm.nih.gov/pubmed/8425440
(37) http://www.ncbi.nlm.nih.gov/pubmed/17242486
(38) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1553030/pdf/gut00684-0094.pdf
(39) http://www.ncbi.nlm.nih.gov/pubmed/776752
(40) http://www.ncbi.nlm.nih.gov/pubmed/6588541
(41) http://wholeleaf.com/aloeveraoralconsumption.html
(42) http://www.drmeletis.com/wp-content/uploads/2012/07/Proton-Pump-Inhibitors.pdf
(43) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761965/
(44) http://onlinelibrary.wiley.com/doi/10.1002/ptr.1936/abstract
(45) http://www.ncbi.nlm.nih.gov/pubmed/18481724
(46) http://www.ncbi.nlm.nih.gov/pubmed/21517098
(47) http://www.ncbi.nlm.nih.gov/pubmed/17717919
(48) http://www.ncbi.nlm.nih.gov/pubmed/18476431
(49) http://www.ncbi.nlm.nih.gov/pubmed/17578313
(50) http://www.ncbi.nlm.nih.gov/pubmed/17717918

Quick and Easy Healthy Kid Loved Lunch Box Recipe: Honey granola dip

Posted Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Recipes contributed by The Lunch Box, Packed with fun, healthy meals that keep them smiling, by Kate McMillan and Sarah Putman Clegg, published by Weldonowen.

Fill a small airtight container about halfway with plain or vanilla yogurt. Add a layer of granola and then another layer of yogurt. Top with a generous drizzle of honey and a sprinkling of granola. Closed tightly and refrigerate until ready to go. Pack sliced or skewered fruit dippers (see below) along with the dip. Make 1 serving.

Fruit dippers
* fresh apple slices or dried apple chips
* Dried apricot
* Dried banana chips
* Fresh berries or grapes skewered onto toothpicks
* Dried mango strips
* Cantaloupe or honeydew melon slices
* Fresh peach or nectarine slices
* Fresh pineapple wedges
* Halved strawberries

For other Healthy Kid loved recipes http://kylejnorton.blogspot.ca/p/recipes.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sunday, 22 February 2015

War of Hue City Central Vietnam by 林軍碩

According to the resource, the below lost poem was written by 林軍碩, on early 1975 at Hue city war zone. Mr. 林, the former editor of department of Chinese literature studies news at university of Minh Duc, faculty of Humanity and Social sciences, at ages of 18, was one of the well known poem writer between 1974 - 1975 in Saigon, south Vietnam, before communist taking power. He also involved in many charitable events in assisting the refugees to rebuild their homes in the War zone(1974-1975). Loved by his Chao zhou community lead by Mr. 陳城, Mr. 林, was considered by his community as one of the best next generation leaders at that tine.

Quick and Easy Healthy Kid Loved Lunch Box Recipe: Vanilla-raspberry side

Posted Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

Posted By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Recipes contributed by The Lunch Box, Packed with fun, healthy meals that keep them smiling, by Kate McMillan and Sarah Putman Clegg, published by Weldonowen.

Fill a small airtight container about halfway with vanilla yogurt. Top with a thin, smooth layer of raspberry jam. Add another layer of yogurt. top the yogurt with spiral or smiley face of jam, if you like. Closed tightly and refrigerate until ready to go. Pack sliced or skewered fruit dippers (see below) along with the dip. Make 1 serving

Fruit dippers
* fresh apple slices or dried apple chips
* Dried apricot
* Dried banana chips
* Fresh berries or grapes skewered onto toothpicks
* Dried mango strips
* Cantaloupe or honeydew melon slices
* Fresh peach or nectarine slices
* Fresh pineapple wedges
* Halved strawberries

For other Healthy Kid loved recipes http://kylejnorton.blogspot.ca/p/recipes.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Saturday, 21 February 2015

(4th edited )Most common diseases of Elders- Diseases of Central Nervous system(CNS): TCM herbal Shui Fei Zi (Milk thistle) treatments of Dementia Caused by Toxin Accumulation

Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way

If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Diseases of Central Nervous system

Dementia

About 5-8% of all people over the age of 65 have some form of dementia, and this number doubles every five years above that age. Dementia is the loss of mental ability, severe enough to interfere with people's every life and Alzheimer's disease is the most common type of dementia in aging people.
V. Treatments
C. In traditional Chinese Medicine Perspective(*)
Based on Chinese ancient medical records. causes of dementia are the results of (*)

C.5. According to TCM philosophy, dementia is also to be induced by the combination/or of Kidney essence vacuity and toxin (turbid phlegm).
C.5.1. Dementia due to toxins accumulation
Toxins accumulation in internal organs disturbed the balance of immunity(1213)(1214) may cause impairment of food intake regulation(1215), exhibition of phlegm(1208)(1208)(1210), retention of fluid(1211)(1212) and blood statsis(1209) induced early the onset of dementia, in aging population with depletion of kidney-essence(1208)(1209), according to traditional Chinese medicine.

Herbal Medicine for toxins elimination
Chinese Herbal medicine for toxins elimination
1. Shui Fei Zi or Milk thistle (Silybum marianum)
Shui fei zi, the bitter and cold herb, is also known as milk thistle, native to Western Europe and northern Africa, used in traditional Chinese medicine to improve liver function(1193)(1194)(1210), promote the flow of breast milk(1207), bile secretion(1200), anti depression(1201) and anti tumors(1196)(1197)(1198), inhibit allergic effects(1195)(1199), treat hepatitis C(1202)(1203), cirrhosis(1205) and liver fibrosis(1206), by enhancing function of liver and gallbladder channels(1204)

Phytochemicals
1. Flavonoid
2. Fumaric acid
3. Silymarin
4. Isosilybin,
5. Dehydrosilybin,
6. Silydianin
7. Silychristin
8. Cinnamic acid
9. Myristic acid
10. Palmitelaidic acid
10. Arachidic acid
11. Etc.

Shui Fei Zi or Milk thistle used in the treatment and prevention of dementia(1218) in traditional Chinese medicine, may be due to its effectiveness of phytochemicals Silymarin and Silibinin in ameliorated amyloid pathology(1216) and oxidative stress(1216)(1217) through attenuated levels of lipid peroxidation (malondialdehyde) and antioxidant (glutathione) in the hippocampus(1217).

1.1. In Alzheimer's disease
Alzheimer disease (AD). a neurodegenerative disorders is the most prevalent diseases in the United States, in aging population(1219). Silymarin, a phytochemical found abundantly in milk thistle, in age related disorders like neurodegenerative diseases improved locomotion rate, higher response to stimuli and tolerance to stress, in C.elegans Alzheimer's Model, through delayed paralysis via enhanced resistance to oxidative stress(1220). In rat induced Alzheimer's disease model, the phytochemical also inhibited amyloid formation(1222) and suppressed amyloid protein precursor (APP) expression(1222)and reduced neurotoxicity in PC12 cells(1222) in improvement memory(1223) and learning function(1221).

1.2. In Parkinson disease
In a mouse model of Parkinson's disease, causes of mitochondrial dysfunction and selective cells death of dopaminergic neurons, silibinin, derivative of silymarin, protected mitochondria through attenuated motor deficit and dopaminergic neuronal loss(1224) and anti oxidative and anti inflammatory pathways(1225).

1.3. In neuroprotective effects
In focal cerebral ischemia, silymarin (SM), a mixture of flavonolignans extracted from the milk thistle exerted it neuroprotective effects, in upregulating the antioxidant status and lowering the apoptotic response in slowing down the progression of neurodegeneration(1226) and preventing inflammation-related neurodegenerative disease(1227) and ROS causs of oxidative damage to macromolecules in the brain(1230).

1.4. In cognitive impairment
In cognitive deficit mice model, silibinin exhibited its anti cognitive impairment effects through amelioration of decreases in dopamine and serotonin levels in the prefrontal cortex and hippocampus, (1228). In amyloid beta peptide-induced memory impairment, the chemicals also improve cognitive memory deficits through attenuated the Abeta(25-35)- accumulation of malondialdehyde and depletion of glutathione in the hippocampus(1229).

Reprinted from Norton Journal, Volume I, Most Common Diseases of Ages of 50 Plus - Chapter of Diseases of Central Nervous system(CNS): Dementia - Treatments in Traditional Chinese Herbal Medicine by Kyle J. Norton.

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(*) http://www.hindawi.com/journals/ecam/2012/692621/
(1193) http://www.ncbi.nlm.nih.gov/pubmed/9468229
(1194) http://www.ncbi.nlm.nih.gov/pubmed/20564545
(1195) http://www.ncbi.nlm.nih.gov/pubmed/23121838
(1196) http://www.ncbi.nlm.nih.gov/pubmed/23879966
(1197) http://www.ncbi.nlm.nih.gov/pubmed/24574320
(1198) http://www.ncbi.nlm.nih.gov/pubmed/25242120
(1199) http://www.ncbi.nlm.nih.gov/pubmed/23701595
(1200) http://www.ncbi.nlm.nih.gov/pubmed/17692492
(1201) http://www.ncbi.nlm.nih.gov/pubmed/25431050
(1202) http://www.ncbi.nlm.nih.gov/pubmed/25247194
(1203) http://www.ncbi.nlm.nih.gov/pubmed/22797645
(1204) http://alternativehealing.org/shui_fei_ji.htm
(1205) http://www.ncbi.nlm.nih.gov/pubmed/15277093
(1206) http://www.ncbi.nlm.nih.gov/pubmed/22087179
(1207) http://www.ncbi.nlm.nih.gov/pubmed/23468043
(1208) http://www.ncbi.nlm.nih.gov/pubmed/24187864
(1209) http://www.ncbi.nlm.nih.gov/pubmed/22500712
(1210) http://www.ncbi.nlm.nih.gov/pubmed/24155069
(1211) http://www.ncbi.nlm.nih.gov/pubmed/25155658
(1212) http://www.ncbi.nlm.nih.gov/pubmed/25162367
(1213) http://www.ncbi.nlm.nih.gov/pubmed/24719080
(1214) http://www.ncbi.nlm.nih.gov/pubmed/22866982
(1215) http://www.ncbi.nlm.nih.gov/pubmed/16769094
(1216) http://www.ncbi.nlm.nih.gov/pubmed/21185897
(1217) http://www.ncbi.nlm.nih.gov/pubmed/19552690
(1218) http://www.ncbi.nlm.nih.gov/pubmed/21071836
(1219) http://www.ncbi.nlm.nih.gov/pubmed/25696782
(1220) http://www.ncbi.nlm.nih.gov/pubmed/25613505
(1221) http://www.ncbi.nlm.nih.gov/pubmed/24460990
(1222) http://www.ncbi.nlm.nih.gov/pubmed/21071836
(1223) http://www.ncbi.nlm.nih.gov/pubmed/19638571
(1224) http://www.ncbi.nlm.nih.gov/pubmed/25677261
(1225) http://www.ncbi.nlm.nih.gov/pubmed/24660866
(1226) http://www.ncbi.nlm.nih.gov/pubmed/21840019
(1227) http://www.ncbi.nlm.nih.gov/pubmed/20833521
(1228) http://www.ncbi.nlm.nih.gov/pubmed/19857526
(1229) http://www.ncbi.nlm.nih.gov/pubmed/19552690
(1230) http://www.ncbi.nlm.nih.gov/pubmed/19647779

Email Scam: Contact Person: Mr. Nicholas Donnie. E-mail: (brihcolumlottbc49@qq.com)‏

Scam E Mail received 20/02/2015

Contact Person: Mr. Nicholas Donnie. E-mail: (brihcolumlottbc49@qq.com)

BRITISH COLUMBIA NATIONAL LOTTERY BC-49 (faaloughaim@uod.edu.sa)

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20/02/2015

Dear: e-Mail Winner,

This is to inform you that your e-Mail Address have WON you the sum of 1,550,952.00 (One Million Five Hundred And Fifty Thousand Nine Hundred And Fifty two Pounds Sterling) from the British Columbia National Lottery BC-49 Online Promo 2015. The Promotional Award was held on Saturday 28th of January 2015, in Liverpool United Kingdom. Your e-mail address attached to BC-49 Lottery Chip NO: IMP/73253CA/2015 which drew the

Winning No: 07 12 15 20 22 25

Bonus No: 14.

Contact Person: Mr. Nicholas Donnie.

E-mail: (brihcolumlottbc49@qq.com)

Telephone Number: +447011149203

FILL THE PAYMENT PROCESSING FORM BELOW:

1.Full Names:________

2.Address:__________

3.Nationality:_______________

4.Age:________

5.Occupation:________

6.Winning e-Mail Address:______