By Kyle J. Norton
Obesity is defined as a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
How do calculate your BMI index
BMI= weight (kg)/ height (m2)
Rheumatoid Arthritis is defined as a conditon of inflammation of the joints of which may also affects other tissues and organs, according to the statistic of article of Rheumatoid Arthritis of the arthritis society, about one out of every 100 Canadians has rheumatoid arthritis (RA). That’s about 300,000 Canadians and a leading cause of disability.
How Obesity associates with Rheumatoid Arthritis
1. According to the study of "Associations between body mass, radiographic joint damage, adipokines and risk factors for bone loss in rheumatoid arthritis" by Baker JF, George M, Baker DG, Toedter G, Von Feldt JM, Leonard MB.,posted in PubMed, researchers found that in the evaluating the association between BMI and radiographic joint damage (RJD) in RA.Methods,...Higher BMI was independently associated with less RJD and was greatest in participants with risk factors for bone loss. Future studies are needed to examine the associations between RJD, obesity, weight loss and osteoporosis.
2. In the abstract of study of "Radiographic joint damage in early rheumatoid arthritis is highly dependent on body mass index" by Westhoff G, Rau R, Zink A., posted in PubMed, researchers found that BMI provides a risk estimate of joint damage in RA patients. Further studies are needed to elucidate the association between BMI, RF, and joint damage in RA and the possible role of adipose tissue.
3. In the study of "Obesity, adipose tissue and rheumatoid arthritis: coincidence or more complex relationship?" by Derdemezis CS, Voulgari PV, Drosos AA, Kiortsis DN., posted in PubMed, researchers indicated that it is also implicated in obesity, a low-grade inflammatory state, as well as inflammatory conditions including rheumatoid arthritis (RA), an autoimmune disease where anti- and pro-inflammatory cytokine balance is critical is critical.
4. According to the study of "Abnormal body composition phenotypes in Vietnamese women with early rheumatoid arthritis" by Dao HH, Do QT, Sakamoto J., posted in PubMed, researchers found that women with early RA had a significantly higher proportion of unhealthy body composition phenotypes, higher total and truncal FM and lower appendicular LM than controls. Disease activity and disability scores were associated with unhealthy body composition. These findings suggest that clinicians should encourage muscle strengthening and fat loss in RA patients to reduce their disability.
5. According to the abstract of the study of "Obesity in rheumatoid arthritis" by Stavropoulos-Kalinoglou A, Metsios GS, Koutedakis Y, Kitas GD, posted in PubMed, researchers indicated that Obesity is a major threat for public health and its study has attracted significant attention in the general population, predominantly due to its association with significant metabolic and cardiovascular complications. In RA research, BMI is frequently reported as a demographical variable, but obesity, as such, has received little interest. This is surprising, in view of the clear associations of obesity with other arthritides, particularly OA, but also in view of the now-clear association of RA with increased cardiovascular morbidity and mortality.
6. Etc.
Treatments of Obesity and Rheumatoid Arthritis
1. In a study of "Body composition phenotypes in systemic lupus erythematosus and rheumatoid arthritis: a comparative study of Caucasian female patients" by Santos MJ, Vinagre F, Canas da Silva J, Gil V, Fonseca JE., posted in PubMed, researchers found that women with SLE (systemic lupus erythematosus ) or RA (Rheumatoid Arthritis) diagnosis are more likely to have abnormal body composition phenotype, with some differences existing between these two conditions. Changes in body composition are partly explained by the inflammatory burden of disease and its treatment.
2. According to the study of "Role of diet in rheumatic disease" by Li S, Micheletti R., posted in PubMed, researchers wrote that Millions of people suffer from rheumatic diseases such as gout, fibromyalgia, osteoarthritis, and rheumatoid arthritis. These can be incapacitating and detrimental to quality of life. Diet, nutrition, and weight loss have shown promise in alleviating some of this disease burden. These lifestyle changes may give patients a feeling of control and ownership over their disease as well as a nonpharmacologic means of treatment.
3. In a study of "What predicts obesity in patients with rheumatoid arthritis? An investigation of the interactions between lifestyle and inflammation" by Stavropoulos-Kalinoglou A, Metsios GS, Smith JP, Panoulas VF, Douglas KM, Jamurtas AZ, Koutedakis Y, Kitas GD., posted in PubMed, researchers concluded that inflammation does not seem to influence BMI and BF in RA. As in the general population, high levels of habitual physical activity associate with low BMI and BF in RA. Energy intake is a major determinant of being underweight in those who consume fewer calories. Further research is needed to investigate the suitability of exercise and diet modalities, and their effects on the body composition of RA patients.
4. Etc.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Monday, 11 August 2014
The best and healthy Fruit Salsa with Cinnamon Chips
Recipe attributed to Quick and easy family favorites by Vickie and JoAnn
Ashley Connelly, Louisa, VA
Kiwis, apple, raspberries, and strawberry make up this colorful salsa. It 'll be a treat that guests will not want to miss.....especially when served with homemade cinnamon chips.
2 kiwis, peeled and diced
2 Golden delicious apples. cored, peeled and diced
1/2 Lb. raspberries
16 Oz. pkg. strawberry, bulled and diced
1 c. plus 2 T. sugar and divided
1 T. brown sugar, packed
3 T. strawberry preserves
1 to 2 T. cinnamon
10 (10-inch) flour tortillas, sliced into wedges
butter flavored non-stick vegetable spray
Combined all fruits into a large bowl, mix in 2 tsp. sugar, brown sugar and strawberry preserves. Cover and chill for 15 minutes.
Mix together remaining 1 cup of sugar and cinnamon. Arrange tortilla wedges in a single layer on an ungreased baking sheet; coat chips with butter flavored vegetable spray. Sprinkle with desired amount of cinnamon-sugar.
Bake at 350 degrees for 8 to 10 minutes. Repeat with remaining tortilla wedges, cool 15 minutes. Serve chips with chilled fruit mixture.
Makes 10 to 15 servings
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Ashley Connelly, Louisa, VA
Kiwis, apple, raspberries, and strawberry make up this colorful salsa. It 'll be a treat that guests will not want to miss.....especially when served with homemade cinnamon chips.
2 kiwis, peeled and diced
2 Golden delicious apples. cored, peeled and diced
1/2 Lb. raspberries
16 Oz. pkg. strawberry, bulled and diced
1 c. plus 2 T. sugar and divided
1 T. brown sugar, packed
3 T. strawberry preserves
1 to 2 T. cinnamon
10 (10-inch) flour tortillas, sliced into wedges
butter flavored non-stick vegetable spray
Combined all fruits into a large bowl, mix in 2 tsp. sugar, brown sugar and strawberry preserves. Cover and chill for 15 minutes.
Mix together remaining 1 cup of sugar and cinnamon. Arrange tortilla wedges in a single layer on an ungreased baking sheet; coat chips with butter flavored vegetable spray. Sprinkle with desired amount of cinnamon-sugar.
Bake at 350 degrees for 8 to 10 minutes. Repeat with remaining tortilla wedges, cool 15 minutes. Serve chips with chilled fruit mixture.
Makes 10 to 15 servings
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
The best snack with Family and Friends: Italian eggplant Sticks
Recipe attributed to Quick and easy family favorites by Vickie and JoAnn
Karen Pitcher
Burleson, TX
Served with marinara sauce or even salsa, this Italian-season veggies will get a big thumbs up from family and friends
3 eggplant peeled
1. cup Italian favored dry bread crumbs
1 tsp. salt
1 tsp. pepper
3 eggs
1/4 cup milk
oil for deep frying
Cue eggplant into3''x1/2' stick; place in ice water for 30 minutes. drain and set aside.
Combined bread crumbs, salt and pepper; set a side. Blend together eggs and milk in a shallow bowl, dip eggplant sticks into egg mixture and dredge in bread crumbs mixture. Arrange eggplant on an ungreased baking sheet. Cover and chill for 20 minutes.
Pour oil to a depth of one inch in a deep skillet; heat oil to 275 degrees. Add eggplant and cook 2 minutes on each side or until golden. Drain on paper towels. Serve 6
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Karen Pitcher
Burleson, TX
Served with marinara sauce or even salsa, this Italian-season veggies will get a big thumbs up from family and friends
3 eggplant peeled
1. cup Italian favored dry bread crumbs
1 tsp. salt
1 tsp. pepper
3 eggs
1/4 cup milk
oil for deep frying
Cue eggplant into3''x1/2' stick; place in ice water for 30 minutes. drain and set aside.
Combined bread crumbs, salt and pepper; set a side. Blend together eggs and milk in a shallow bowl, dip eggplant sticks into egg mixture and dredge in bread crumbs mixture. Arrange eggplant on an ungreased baking sheet. Cover and chill for 20 minutes.
Pour oil to a depth of one inch in a deep skillet; heat oil to 275 degrees. Add eggplant and cook 2 minutes on each side or until golden. Drain on paper towels. Serve 6
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sunday, 10 August 2014
To Make the best of beef soup recipe: The Beef stock
Recipe contributed by 125 Best Chinese Recipe1 By Bill Jones and Stephen Wong (Robert Rose)
5 lb. beef bone a(shine or neck)
3 large onion, peeled and roughly chopped
3 carrots, roughly chopped
3 stalks of celery, roughly chopped
1/2 garlic head
1/2 cup tomato paste
3 bay leaves
1 small handful thyme
1 small handful rosemary
1 small handful marjoram
1 bunch parsley stalks
5 whole pepper corns
20 cups water
1, Pace bone in a pan and roast until lightly golden, about 2 hours. Add vegetables and garlic; roast 1 hour. Add tomato paste, stirring to coat. roast 30 minutes.
1. Place roast bones and vegetables in a large stockpot, add remain ingredients. Add more water, if necessary to cover. Bring mixture to a broil; reduce heat and simmer gently for 8 hours, skimming occasionally to remove any foam or impurities that rise to the top. Try not to let the mixture boil or broth will be cloudy.
2. Strain in to container and cool to room temperature before refrigerating. (If hot stock is placed directly in the fridge, it will sometime sour). for a more intensely flavored stock, let liquid cool; return stock to pot and over low heat, simmer until volume is reduced by half.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
5 lb. beef bone a(shine or neck)
3 large onion, peeled and roughly chopped
3 carrots, roughly chopped
3 stalks of celery, roughly chopped
1/2 garlic head
1/2 cup tomato paste
3 bay leaves
1 small handful thyme
1 small handful rosemary
1 small handful marjoram
1 bunch parsley stalks
5 whole pepper corns
20 cups water
1, Pace bone in a pan and roast until lightly golden, about 2 hours. Add vegetables and garlic; roast 1 hour. Add tomato paste, stirring to coat. roast 30 minutes.
1. Place roast bones and vegetables in a large stockpot, add remain ingredients. Add more water, if necessary to cover. Bring mixture to a broil; reduce heat and simmer gently for 8 hours, skimming occasionally to remove any foam or impurities that rise to the top. Try not to let the mixture boil or broth will be cloudy.
2. Strain in to container and cool to room temperature before refrigerating. (If hot stock is placed directly in the fridge, it will sometime sour). for a more intensely flavored stock, let liquid cool; return stock to pot and over low heat, simmer until volume is reduced by half.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
At Last! The Natural PCOS Diet
A Naturopath’s Easy Step-by-Step Guide to Overcome PCOS
by Qualified Australian Naturopath And Hormone Health Expert
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
4 someone who loves Walnuts: Hot and spicy Walnuts
Recipe attributed to Fresh and Easy Meals by Better Homes and Gardens
Nut hits the spot as snack, and this snack is loaded with them. walnuts have more heart-healthy Omega-3 fat than other nuts. Use canola oil in the recipe to boost it Omega 3 content even more.
Prep. 10 minutes
Bake 20 minutes
Cool 15 minutes
Oven 300 degree F
Make 8 (1/4 cup) servings
1 tsp. ground coriander
1 tsp. ground cumin
!/2 tsp. salt
1/4 tsp. freshly ground black pepper
1/2 tsp. cayenne pepper
2 cups walnuts halves
1 tsp. cooking oil
In a small bowl stir together coriander, cumin, salt, black pepper, and cayenne pepper; set aside. Place nuts in a 13x9x2 inch baking pan. Drizzle with the oil, stir to coat. Sprinkle with choice mixture; toss lightly.
Baking in a 300 degrees oven for 20 munities or until nuts are slightly toasted, stirring once or twice. Cool in pan for 15 minutes. Turn out onto paper towels; cool completely. Store, covered in a cool place.
Nutrition facts per serving: 214 Cal. 21 g total fat(2g sat. fat), O mg cholesterol, 147 mg sodium, 4g carbo, 2 g fiber, 5 g pro.
Daily value: 1% vitamin C, 3% calcium, 5% iron.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Nut hits the spot as snack, and this snack is loaded with them. walnuts have more heart-healthy Omega-3 fat than other nuts. Use canola oil in the recipe to boost it Omega 3 content even more.
Prep. 10 minutes
Bake 20 minutes
Cool 15 minutes
Oven 300 degree F
Make 8 (1/4 cup) servings
1 tsp. ground coriander
1 tsp. ground cumin
!/2 tsp. salt
1/4 tsp. freshly ground black pepper
1/2 tsp. cayenne pepper
2 cups walnuts halves
1 tsp. cooking oil
In a small bowl stir together coriander, cumin, salt, black pepper, and cayenne pepper; set aside. Place nuts in a 13x9x2 inch baking pan. Drizzle with the oil, stir to coat. Sprinkle with choice mixture; toss lightly.
Baking in a 300 degrees oven for 20 munities or until nuts are slightly toasted, stirring once or twice. Cool in pan for 15 minutes. Turn out onto paper towels; cool completely. Store, covered in a cool place.
Nutrition facts per serving: 214 Cal. 21 g total fat(2g sat. fat), O mg cholesterol, 147 mg sodium, 4g carbo, 2 g fiber, 5 g pro.
Daily value: 1% vitamin C, 3% calcium, 5% iron.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Obesity Complication of Pancreatitis
By Kyle J. Norton
Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
B. How to calculate your BMI index
BMI= weight (kg)/ height (m2)
C. Pancreatitis is defined as a condition of inflammation of the pancreas as its no longer function normally in secreting digestive juices, or enzymes. Pancreatitis can be acute or chronic.
D. How Obesity associates with Pancreatitis
1. According to the abstract of the study of "Influence of obesity on the severity and clinical outcome of acute pancreatitis" by Shin KY, Lee WS, Chung DW, Heo J, Jung MK, Tak WY, Kweon YO, Cho CM, posted in PubMed, researchers indicated that When compared with normal patients (BMI 18.5 to 22.9), all categories with a BMI ≥23 had an increased risk of developing a severe form of acute pancreatitis (p=0.003) and all categories with a BMI ≥25 significantly predicted severity (p<0.001). Patients with class 1 obesity (BMI 25 to 29.9) developed significantly more systemic and metabolic complications and concluded that Overweightedness and obesity were found to be associated with a higher risk of developing severe pancreatitis. Further studies are needed to establish the precise prognostic value of obesity in members of the population with low BMIs.
2. In a study of "The impact of obesity on the course and outcome of acute pancreatitis" by Abu Hilal M, Armstrong T., posted in PubMed, researchers filed the conclusion that This has led to proposed modifications of acute pancreatitis scoring systems to include obesity as an independent primary predictive factor of severe disease. Obesity is associated with a low-grade inflammatory state, which may predispose obese patients to such complications. Furthermore, visceral obesity and visceral adipose tissue may be particularly important in underlying the pathophysiology of these observations.
3. In another study of "Obesity: a risk factor for severe acute biliary and alcoholic pancreatitis" by Suazo-Baráhona J, Carmona-Sánchez R, Robles-DÃaz G, Milke-GarcÃa P, Vargas-Vorácková F, Uscanga-DomÃnguez L, Peláez-Luna M., posted in PubMed, researchers filed the result that Prevalence of obesity was 57%. Thirty-eight percent of the obese patients developed complications as compared with 21% of the nonobese (RR=1.74; 95% CI, 1-2.9). The risk for severe AP increased according to the degree of obesity. Pancreatic and peripancreatic necrosis was more common in obese patients (17.6% vs 6%), as was the incidence of infectious complications. The risk for severe AP was highest in obese patients with either alcoholic (RR=5.3; 95% CI, 1.2-23) or biliary etiology (RR=5.2, 95% CI, 1-26).
4. According to the abstract of the study of "Obesity: an important prognostic factor in acute pancreatitis" by Funnell IC, Bornman PC, Weakley SP, Terblanche J, Marks IN., posted in PubMed, researchers concluded that obesity had a sensitivity of 63 per cent and a specificity of 95 per cent for predicting disease severity. When five obese women with gallstone pancreatitis were excluded, the sensitivity of obesity increased to 86 per cent. Severe pancreatitis occurred in all eight obese patients with disease of an alcoholic aetiology. These data suggest that increased fat deposits in the peripancreatic and retroperitoneal spaces in obese patients may increase the risk of peripancreatic fat necrosis, abscess and death. Consideration should be given to including obesity as a prognostic factor in acute pancreatitis.
5. In the study of "Experimental evidence of obesity as a risk factor for severe acute pancreatitis" by Frossard JL, Lescuyer P, Pastor CM., posted in PubMed, researchers indicated that Several hypotheses have been suggested: (1) obese patients have an increased inflammation within the pancreas; (2) obese patients have an increased accumulation of fat within and around the pancreas where necrosis is often located; (3) increase in both peri- and intra-pancreatic fat and inflammatory cells explain the high incidence of pancreatic inflammation and necrosis in obese patients; (4) hepatic dysfunction associated with obesity might enhance the systemic inflammatory response by altering the detoxification of inflammatory mediators; and (5) ventilation/perfusion mismatch leading to hypoxia associated with a low pancreatic flow might reduce the pancreatic oxygenation and further enhance pancreatic injury. Recent experimental investigations also show an increased mortality and morbidity in obese rodents with acute pancreatitis and the implication of the adipokines leptin and adiponectin. Such models are important to investigate whether the inflammatory response of the disease is enhanced by obesity. It is exciting to speculate that manipulation of the adipokine milieu has the potential to influence the severity of acute pancreatitis.
6. Etc.
E. Treatments of Obesity and Pancreatitis
1, In the abstract of the study of "The influence of dietary restriction on the development of diabetes and pancreatitis in female WBN/Kob-fatty rats" by Akimoto T, Terada M, Shimizu A, Sawai N, Ozawa H., posted in PubMed, researchers stated that pathological changes of the pancreas were observed in female fatty rats. All female fatty rats showed severe interlobular, intra-lobular and intra-islet fibrosis. In female fatty rats of the restricted feeding group, pathological changes of the pancreas were milder those of the free-feeding fatty group. Although dietary restriction could not completely prevent pancreatitis in female fatty rats, the development of diabetes was inhibited by its reduction of the severity of pancreatitis.
2. According to the study of "Fat replacement of the malignant pancreatic tissue after neoadjuvant therapy" by Makay O, Kazimi M, Aydin U, Nart D, Yilmaz F, Zeytunlu M, Goker E, Coker A., posted in PubMed, researchers found that The tissue pathology revealed lipomatosis of the pancreas. He was disease-free and symptom-free at 1 year follow-up. To our knowledge, this is the first report in the literature of pancreatic head carcinoma with total fat replacement of the pancreas after neoadjuvant chemoradiotherapy.
3. In the study of "Pancreatic surgery" by Hines OJ, Reber HA., posted in PubMed, researcher indicated that Recent evidence suggests that obese patients with pancreatic cancer appear to have more advanced disease at the time of diagnosis and a worse outcome following resection. The issues surrounding adjuvant treatment for pancreatic cancer with chemotherapy and/or radiation therapy continue to be evaluated....... and summarized that each year more is learned about the natural history of pancreatic lesion. For those dedicated to the study and treatment of this gland, several new advances help the clinician with treatment decisions.
4. Etc.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
B. How to calculate your BMI index
BMI= weight (kg)/ height (m2)
C. Pancreatitis is defined as a condition of inflammation of the pancreas as its no longer function normally in secreting digestive juices, or enzymes. Pancreatitis can be acute or chronic.
D. How Obesity associates with Pancreatitis
1. According to the abstract of the study of "Influence of obesity on the severity and clinical outcome of acute pancreatitis" by Shin KY, Lee WS, Chung DW, Heo J, Jung MK, Tak WY, Kweon YO, Cho CM, posted in PubMed, researchers indicated that When compared with normal patients (BMI 18.5 to 22.9), all categories with a BMI ≥23 had an increased risk of developing a severe form of acute pancreatitis (p=0.003) and all categories with a BMI ≥25 significantly predicted severity (p<0.001). Patients with class 1 obesity (BMI 25 to 29.9) developed significantly more systemic and metabolic complications and concluded that Overweightedness and obesity were found to be associated with a higher risk of developing severe pancreatitis. Further studies are needed to establish the precise prognostic value of obesity in members of the population with low BMIs.
2. In a study of "The impact of obesity on the course and outcome of acute pancreatitis" by Abu Hilal M, Armstrong T., posted in PubMed, researchers filed the conclusion that This has led to proposed modifications of acute pancreatitis scoring systems to include obesity as an independent primary predictive factor of severe disease. Obesity is associated with a low-grade inflammatory state, which may predispose obese patients to such complications. Furthermore, visceral obesity and visceral adipose tissue may be particularly important in underlying the pathophysiology of these observations.
3. In another study of "Obesity: a risk factor for severe acute biliary and alcoholic pancreatitis" by Suazo-Baráhona J, Carmona-Sánchez R, Robles-DÃaz G, Milke-GarcÃa P, Vargas-Vorácková F, Uscanga-DomÃnguez L, Peláez-Luna M., posted in PubMed, researchers filed the result that Prevalence of obesity was 57%. Thirty-eight percent of the obese patients developed complications as compared with 21% of the nonobese (RR=1.74; 95% CI, 1-2.9). The risk for severe AP increased according to the degree of obesity. Pancreatic and peripancreatic necrosis was more common in obese patients (17.6% vs 6%), as was the incidence of infectious complications. The risk for severe AP was highest in obese patients with either alcoholic (RR=5.3; 95% CI, 1.2-23) or biliary etiology (RR=5.2, 95% CI, 1-26).
4. According to the abstract of the study of "Obesity: an important prognostic factor in acute pancreatitis" by Funnell IC, Bornman PC, Weakley SP, Terblanche J, Marks IN., posted in PubMed, researchers concluded that obesity had a sensitivity of 63 per cent and a specificity of 95 per cent for predicting disease severity. When five obese women with gallstone pancreatitis were excluded, the sensitivity of obesity increased to 86 per cent. Severe pancreatitis occurred in all eight obese patients with disease of an alcoholic aetiology. These data suggest that increased fat deposits in the peripancreatic and retroperitoneal spaces in obese patients may increase the risk of peripancreatic fat necrosis, abscess and death. Consideration should be given to including obesity as a prognostic factor in acute pancreatitis.
5. In the study of "Experimental evidence of obesity as a risk factor for severe acute pancreatitis" by Frossard JL, Lescuyer P, Pastor CM., posted in PubMed, researchers indicated that Several hypotheses have been suggested: (1) obese patients have an increased inflammation within the pancreas; (2) obese patients have an increased accumulation of fat within and around the pancreas where necrosis is often located; (3) increase in both peri- and intra-pancreatic fat and inflammatory cells explain the high incidence of pancreatic inflammation and necrosis in obese patients; (4) hepatic dysfunction associated with obesity might enhance the systemic inflammatory response by altering the detoxification of inflammatory mediators; and (5) ventilation/perfusion mismatch leading to hypoxia associated with a low pancreatic flow might reduce the pancreatic oxygenation and further enhance pancreatic injury. Recent experimental investigations also show an increased mortality and morbidity in obese rodents with acute pancreatitis and the implication of the adipokines leptin and adiponectin. Such models are important to investigate whether the inflammatory response of the disease is enhanced by obesity. It is exciting to speculate that manipulation of the adipokine milieu has the potential to influence the severity of acute pancreatitis.
6. Etc.
E. Treatments of Obesity and Pancreatitis
1, In the abstract of the study of "The influence of dietary restriction on the development of diabetes and pancreatitis in female WBN/Kob-fatty rats" by Akimoto T, Terada M, Shimizu A, Sawai N, Ozawa H., posted in PubMed, researchers stated that pathological changes of the pancreas were observed in female fatty rats. All female fatty rats showed severe interlobular, intra-lobular and intra-islet fibrosis. In female fatty rats of the restricted feeding group, pathological changes of the pancreas were milder those of the free-feeding fatty group. Although dietary restriction could not completely prevent pancreatitis in female fatty rats, the development of diabetes was inhibited by its reduction of the severity of pancreatitis.
2. According to the study of "Fat replacement of the malignant pancreatic tissue after neoadjuvant therapy" by Makay O, Kazimi M, Aydin U, Nart D, Yilmaz F, Zeytunlu M, Goker E, Coker A., posted in PubMed, researchers found that The tissue pathology revealed lipomatosis of the pancreas. He was disease-free and symptom-free at 1 year follow-up. To our knowledge, this is the first report in the literature of pancreatic head carcinoma with total fat replacement of the pancreas after neoadjuvant chemoradiotherapy.
3. In the study of "Pancreatic surgery" by Hines OJ, Reber HA., posted in PubMed, researcher indicated that Recent evidence suggests that obese patients with pancreatic cancer appear to have more advanced disease at the time of diagnosis and a worse outcome following resection. The issues surrounding adjuvant treatment for pancreatic cancer with chemotherapy and/or radiation therapy continue to be evaluated....... and summarized that each year more is learned about the natural history of pancreatic lesion. For those dedicated to the study and treatment of this gland, several new advances help the clinician with treatment decisions.
4. Etc.
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Saturday, 9 August 2014
Obesity Complication of Type II Diabetes
By Kyle J. Norton
Obesity is defined as a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
Type II diabetesDiabetes is defined as a medical condition of insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in the pancreas dying off or receptor sites clogged up by the accumulation of fat and cholesterol. In some case, diabetes is also caused by allergy reactions of cells in our body.
How do calculate your BMI indexBMI= weight (kg)/ height (m2)
How obesity cause type II diabetes
Type II diabetes is a result of insulin resistance and obesity is considered as a risk factor for developing insulin resistance.
1. According to the article of "Obesity and insulin resistance" by Barbara B. Kahn and Jeffrey S. Flier (1), researchers indicated that the association of obesity with type 2 diabetes has been recognized for decades, and the major basis for this link is the ability of obesity to engender insulin resistance. Insulin resistance is a fundamental aspect of the etiology of type 2 diabetes and is also linked to a wide array of other pathophysiologic sequelae including hypertension, hyperlipidemia, atherosclerosis (i.e., the metabolic syndrome, or syndrome X), and polycystic ovarian disease.
1. Can Gene and Inherited factor cause of Obesity and type II diabetes be changed
Obesity and type II diabetes as a result of genetic susceptible or heredity can be prevented, according to the study of " Lifestyle and Genetics in Obesity and type 2 Diabetes." by Temelkova-Kurktschiev T, Stefanov T. (Source from Medicobiological Unit.) posted in PubMed, researchers found that gene-lifestyle interaction studies suggest that
a. Genetic susceptibility to obesity and type 2 diabetes may be partially or totally kept under control by healthy lifestyle or lifestyle modification and that lifestyle determines whether an individual is likely to develop the disease.
b. Inherited factors, however, seem to influence individual response to a lifestyle intervention program and even the motivation for lifestyle change. Personalized interventions according to genotype may be, therefore, considered in the future.
By then lifestyle modification targeting dietary change and increased physical activity may be recommended for successful obesity and type 2 diabetes prevention irrespectively of genetic susceptibility.
2. Leptin and Obesity and Type 2 Diabetes
Since leptin is the protein product of the obese gene, many researchers have tries to develop the mew approach to treat obesity and type 2 diabetes. In a study of " Novel Approaches to the Treatment of Obesity and Type 2 Diabetes Mellitus: Bioactive Leptin-Related Synthetic Peptide Analogs." by Grasso P. (Source from Department of Medicine, Division of Endocrinology and Metabolism Albany Medical College, MC 141, Albany, NY 12208, USA. grassop@mail.amc.edu), posted in PubMed, researches indicated that The pleiotropic nature of leptin has been confirmed by demonstration of a role for leptin in hematopoiesis, angiogenesis, immune function, osteogenesis, reproduction, and wound healing. Unfortunately, the results of the majority of clinical trials with recombinant human leptin indicated that its effectiveness in restoring energy balance and correcting obesity-related endocrinopathies in genetically obese rodent models extended only to the management of those rare forms of human obesity caused by mutation in the ob gene. Failure of leptin in the clinic, and withdrawal of fenfluramine, phentermine, and sibutrimine from clinical use in the United States, have stimulated new approaches in the development of anti-obesity and anti-diabetes pharmacophores.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
(1) Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USAAddress correspondence to: Barbara B. Kahn, Division of Endocrinology and Metabolism, Beth Israel Deaconess Medical Center, 99 Brookline Avenue, Boston, Massachusetts 02215, USA. Phone: (617) 667-5422; Fax: (617) 667-2927; E-mail: bkahn@caregroup.harvard.edu. The Journal of Clinical investigation
Obesity is defined as a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
Type II diabetesDiabetes is defined as a medical condition of insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in the pancreas dying off or receptor sites clogged up by the accumulation of fat and cholesterol. In some case, diabetes is also caused by allergy reactions of cells in our body.
How do calculate your BMI indexBMI= weight (kg)/ height (m2)
How obesity cause type II diabetes
Type II diabetes is a result of insulin resistance and obesity is considered as a risk factor for developing insulin resistance.
1. According to the article of "Obesity and insulin resistance" by Barbara B. Kahn and Jeffrey S. Flier (1), researchers indicated that the association of obesity with type 2 diabetes has been recognized for decades, and the major basis for this link is the ability of obesity to engender insulin resistance. Insulin resistance is a fundamental aspect of the etiology of type 2 diabetes and is also linked to a wide array of other pathophysiologic sequelae including hypertension, hyperlipidemia, atherosclerosis (i.e., the metabolic syndrome, or syndrome X), and polycystic ovarian disease.
1. Can Gene and Inherited factor cause of Obesity and type II diabetes be changed
Obesity and type II diabetes as a result of genetic susceptible or heredity can be prevented, according to the study of " Lifestyle and Genetics in Obesity and type 2 Diabetes." by Temelkova-Kurktschiev T, Stefanov T. (Source from Medicobiological Unit.) posted in PubMed, researchers found that gene-lifestyle interaction studies suggest that
a. Genetic susceptibility to obesity and type 2 diabetes may be partially or totally kept under control by healthy lifestyle or lifestyle modification and that lifestyle determines whether an individual is likely to develop the disease.
b. Inherited factors, however, seem to influence individual response to a lifestyle intervention program and even the motivation for lifestyle change. Personalized interventions according to genotype may be, therefore, considered in the future.
By then lifestyle modification targeting dietary change and increased physical activity may be recommended for successful obesity and type 2 diabetes prevention irrespectively of genetic susceptibility.
2. Leptin and Obesity and Type 2 Diabetes
Since leptin is the protein product of the obese gene, many researchers have tries to develop the mew approach to treat obesity and type 2 diabetes. In a study of " Novel Approaches to the Treatment of Obesity and Type 2 Diabetes Mellitus: Bioactive Leptin-Related Synthetic Peptide Analogs." by Grasso P. (Source from Department of Medicine, Division of Endocrinology and Metabolism Albany Medical College, MC 141, Albany, NY 12208, USA. grassop@mail.amc.edu), posted in PubMed, researches indicated that The pleiotropic nature of leptin has been confirmed by demonstration of a role for leptin in hematopoiesis, angiogenesis, immune function, osteogenesis, reproduction, and wound healing. Unfortunately, the results of the majority of clinical trials with recombinant human leptin indicated that its effectiveness in restoring energy balance and correcting obesity-related endocrinopathies in genetically obese rodent models extended only to the management of those rare forms of human obesity caused by mutation in the ob gene. Failure of leptin in the clinic, and withdrawal of fenfluramine, phentermine, and sibutrimine from clinical use in the United States, have stimulated new approaches in the development of anti-obesity and anti-diabetes pharmacophores.
Weight Loss the Easy Ways
Andrea Albright Featured on Health and Fitness Jan. 2015
will Personally Coach You How to Get There The Easy Way
If You Are Looking For a SoulMate
Celebrity Patti Stanger Will Coach You To Get Him/Her
and Keep Him/Her for Good,The Simple Way
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
(1) Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USAAddress correspondence to: Barbara B. Kahn, Division of Endocrinology and Metabolism, Beth Israel Deaconess Medical Center, 99 Brookline Avenue, Boston, Massachusetts 02215, USA. Phone: (617) 667-5422; Fax: (617) 667-2927; E-mail: bkahn@caregroup.harvard.edu. The Journal of Clinical investigation
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