Herbal therapy - Chaste tree berry (Vitex agnus-castus) Anti Cancer Effects

Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of year as anaphrodisiac herb. It is considered as a Queen herb in treating menstrual problems and discomforts by taking it in a prolonged period of time. There was report that chaste tree berry stems and leaves used by women as bedding "to cool the heat of lust" during the time of the Thesmophoria,

Chemical constituents
1.  β-citronellol
2. Labdane-type diterpenoids,
3. Halimane-type diterpenoid,
4. Oleanane-type triterpenoids,
5. Ursane-type triterpenoids,
6. Sesquiterpenoid,
7.  Flavonoid
8. Viteagnusins C, D, E, F, G, and H
9. Abietane-type diterpenoids

Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.

In human uterine cervical canal fibroblast (HCF), human embryo fibroblast (HE-21), ovarian cancer (MCF-7), cervical carcinoma (SKG-3a), breast carcinoma (SKOV-3), gastric signet ring carcinoma (KATO-III), colon carcinoma (COLO 201), and small cell lung carcinoma (Lu-134-A-H) cells, crude extract prepared with ethanol from dried ripened Vitex agnus-castus fruits, inhibited SKOV-3, KATO-III, COLO 201, and Lu-134-A-H cell lines through  its cytotoxic activity and apoptosis(1).
In a human gastric signet ring carcinoma cell line, KATO-III, according to Tokyo University of Pharmacy and Life Science, ethanol extract of the dried ripe fruit of Vitex agnus-castus (Vitex) also displayed cytotoxic activity through intracellular oxidative stress and mitochondrial membrane damage(2).  In prostate epithelial cell lines (BPH-1, LNCaP, PC-3), the Extracts of Vitex agnus-castus fruits (VACF), inhibited proliferation and induced apoptosis in a concentration-dependent manner(3).


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References
(1) Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth by Ohyama K¹, Akaike T, Hirobe C, Yamakawa T.(PubMed)
(2) Human gastric signet ring carcinoma (KATO-III) cell apoptosis induced by Vitex agnus-castus fruit extract through intracellular oxidative stress by Ohyama K¹, Akaike T, Imai M, Toyoda H, Hirobe C, Bessho T.(PubMed)
(3) A Vitex agnus-castus extract inhibits cell growth and induces apoptosis in prostate epithelial cell lines by Weisskopf M¹, Schaffner W, Jundt G, Sulser T, Wyler S, Tullberg-Reinert H.(PubMed)

Raw and Vegan recipe - Sweet cranberry Kale salad

Raw can Roll Cafe (www.rawcanrollcafe.com)
Prep. 15 minutes
1 bunch kale, devined and chopped
4 ounces apple infused dried cranberries or plain dried cranberry
1/4 chopped small apple (with or without peel)
2 ounces walnuts
2 tbsp. agave
1 tsp. orange juice
1tsp. fresh ground pepper
Himalayan pink salt
Combine ingredients together and toss, making sure it it thoroughly ciast with the salt and orange juice.

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The best of using leftover rice salad - Fancy rice salad

Recipe attributed to Company's Coming Salads by Jean Pare
Turn leftover rice into this yummy dish. Serve on lettuce with a roll

Cooked rice, cold  1 cup  (250ml)
Crushed pineapple, drained4 oz.  (398 ml)
Granulated sugar  1/4 cup  (50ml)
Whipping cream ( or 1 envelope topping) 1 cup (250 ml)
Salad dressing ( or Mayonnaise) 1/4 cup  (50ml)
Lettuce
Maraschino cherries
Combine rice, pineapple and sugar in a bowl. Stir
Beat cream until stiff. Beat in salad dressing. Fold into rice mixture.
Arrange lettuce on plates. Spoon salad in center. Top with a cherry. Serve 6.

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Smoke Paprika and lime Aioli

Recipe by Holiday collection by ATCO blue fame collection

Serve this aioli as a dip for shrimp or as a sauce for shrimp cocktail
1 cup (250ml) mayonnaise
1 tbsp. (15ml) fresh lime juice
1 tsp. (5ml) grated lime peel
1 tsp. (5ml) smoke paprika
1/4 tsp. (1ml) salt
2 cloves garlic, crushed
Combined all ingredients until blenched. Transfer to a serving dish. Cover and refrigerate for at least 2 hours or up to 24 hours. Makes about I cup (250ml).

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Phytochemical Polysulfides and breast cancer

Polysulfides are phytochemicals in a class of chemical compounds containing chains of sulfur atoms, belonging to the group of Organosulfides found abundantly in ioxidized product, including beer, wine, whiskey, garlic oil, etc.

Breast cancer (malignant breast neoplasm) is a cancer started in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk. there is also rare cases that breast cancer starts in other areas of the breast. In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during life time of a women is 1/8.
Eating garlic daily and regularly is associated to reduce risk of cancer due to its properties in stimulated cells arrest at G2/M phase of the cells with a sub-G1 DNA content, through caspase-3 pathway(1). In sensitive (MCF-7) and resistant (Vcr-R) human breast carcinoma cells, Diallyl- and dipropyltetrasulfides showed to inhibit growth of both cancer cell lines, through cell cycle arrest associated to antiproliferative effect(2). The Alexandria University study also supported the role of diallyl trisulfide in inhibition of MCF-7 breast cancer through enhanced the expression levels of FAS and cyclin D1, but not in downregulated the expression levels of Akt and Bcl-2(3).


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will Personally Coach You How to Get There The Easy Way

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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca      References
(1) Anticancer effects of diallyl trisulfide derived from garlic by Seki T¹, Hosono T, Hosono-Fukao T, Inada K, Tanaka R, Ogihara J, Ariga T.(PubMed)
(2) Antiproliferative effect of natural tetrasulfides in human breast cancer cells is mediated through the inhibition of the cell division cycle 25 phosphatases by Viry E¹, Anwar A, Kirsch G, Jacob C, Diederich M, Bagrel D.(PubMed)
(3) Garlic constituent diallyl trisulfide induced apoptosis in MCF7 human breast cancer cells by Malki A¹, El-Saadani M, Sultan AS.(PubMed)
 

Layered shrimp and salsa dip

Recipe by Holiday collection by ATCO blue fame collection
8 oz. (250ml) cream cheese, softened
1/8 tsp. (.05ml) garlic powder
1/8 tsp. (.05ml) hot pepper sauce
1 cup (250ml) medium salsa
2 tbsp. (25ml) chopped fresh cilantro
11/2 cup (375ml) coarsely chopped cooked shrimp
2 tbsp. (25ml) thinly sliced green onion
Using medium speed of an electric mixer, beat together cream cheese garlic powder and hot pepper sauce until blended. Spread cream cheese mixture over bottom of a shallow 6 inch (15cm) serving dish. Combine salsa and cilantro. Spoon over cream cheese mixture. Sprinkle shrimp over salsa mixture. Top with green onion. Serve with crackers or tortilla chips. Serve 6 - 8.

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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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The best of lunch box salad - Carrot raisin salad

Recipe attributed to Company's Coming Salads by Jean Pare
A lunch box winner

Grated carrot  2 cups (500 ml)
Raisin (see note)  1/2 cup  (125 ml)
Salad dressing ( or mayonnaise) 1/3 cup (75 ml)
Vinegar 1tbsp. 15 ml
Put all ingredients into a bowl. Toss to coat. Serve 6.
Note: If raisins are too dry. Covered in equal amount of water to 2 minutes. Let stand until cool. Drain. Pat dry with paper towel.
Variation: Add 1/2 cup (125 ml) chopped celery.

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