Mushroom is a standard name of white button mushroom, the fleshy,
spore-bearing fruiting body of a fungus produced above ground on soil
or on its food source, It is a genus A. Muscaria and belong to the
family Amanitaceae and has been cultivation in many cultures all over the world for foods and health benefits.
Nutrients
1. Carbohydrates
2. Protein
3. Thiamine (Vitamin B1)
4. Riboflavin (Vitamin B2)
5. Niacin (Vitamin B3)
6. Pantothenic acid (Vitamin B5)
7. Calcium
8. Phosphorus
9. Potassium
10. Sodium
11. Selenium
12. Iron
13. Copper
14. Zinc
15. Etc.
Chemical constituents
Astraodorol, Psilocybin, Lectin,
adustin, ribonuclease, nicotine, 2-hydroxy-4-methoxy-6-methylbenzoic
acid, orsellinic acid, melleolide, ergosterol, genistein, daidzein,
daucosterol, genistin, uracil and D-mannitol(a).
Prostate cancer is defined as a condition in which the
cells of prostate has become cancerous, causing abnormal cell growth
which spread to the distant parts of the body. Most prostate cancers
are slow growing and enlarged prostate and prostate cancer may be
detected during the Physical (rectum) exams(1).
In athymic mice, conjugated linoleic acid (CLA), found in white button mushroom
extract and its major component showed to inhibit proliferation in the
prostate cancer cell lines in vitro within 72 hours and to decrease the
prostate tumor size of DU145 and PC3(2). But according to the study by
University of Western Sydney, Agaricus bisporus white button mushroom
(WBM), in a tetrazolium dye
[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide]-based
assay, it showed a little effect on the growth of human colon, prostate, gastric cancer,
and murine Sarcoma 180 cells but breast cancer cell line MCF-7(3).
Button mushrooms with a rich source of vitamin D2 that when consumed can
increase and maintain blood levels of 25-hydroxyvitamin D in a healthy
range(4) of that may lead to reduced risk of prostate cancer(5).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
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References
(a) [Chemical constituents from fungus Armillaria mellea]. by [Article in Chinese] by Yuan XL1, Yan LH, Zhang QW, Wang ZM.(PubMed)
(1) Prostate Cancer (Health tips for better living and living health)
(2) White button mushroom
(Agaricus bisporus) exhibits antiproliferative and proapoptotic
properties and inhibits prostate tumor growth in athymic mice by Adams LS1, Phung S, Wu X, Ki L, Chen S.(PubMed)
(3) Macrophage immunomodulating and antitumor activities of polysaccharides isolated from Agaricus bisporus white button mushrooms by Jeong SC1, Koyyalamudi SR, Jeong YT, Song CH, Pang G.(PubMed)
(4) Photobiology of vitamin D in mushrooms and its bioavailability in
humans by Keegan RJ, Lu Z, Bogusz JM, Williams JE, Holick MF.(PubMed)
(5) Prostate cancer risk and prediagnostic serum 25-hydroxyvitamin D
levels (Finland) by Merja H. Ahonen, Leena Tenkanen, Lyly Teppo, Matti
Hakama, Pentti Tuohimaa (Springer link)
Wednesday, 30 April 2014
Bircher Muesli
Contributed by 4 Ingredients by Kim McCosker and Rachael Bermingham (Atria Books)
Serve 1
1/2 cup natural muesli
1/2 cup orange juice
2 tsp. plain yogurt
1 green apple, grated Soak muesli in Juice for 15 minutes. Mix the remaining ingredients and serve.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Tons of recipes
http://kylejnorton.blogspot.ca/p/recipes.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Tuesday, 29 April 2014
Herbal Ginseng and Infertility
Kyle J. Norton
Ginseng, the King of Chinese herb, according to the literature in Chinese medicine may be the next single herb in enhancing fertility in both sexes. According to the statistic from Centers for Disease Control and Prevention (CDC), approximately 7.3 million women of childbearing age (between 15 and 44) in the US are likely to have impaired fecundity with 11% of population in the US alone were infertile.
Beside improving general well-being, the herb has been used in traditional Chinese medicine to treat sexual dysfunction as well as enhanced sexual behavior(1).
Recent animal studies and confirmed in human case control studies, ginseng had shown a positive effects in enhancing libido, and copulatory performances(1). Ginsenosides, an active chemical compound extracted from ginseng was found not only to improve the sperm quality and count of healthy individuals and patients with treatment-related infertility(2), but also facilitate penile erection through directly inducing the vasodilatation and relaxation of penile corpus cavernosum(3).
In treatment of sexual dysfunction, ginsenoside also induced Nitric oxide (NO) function in the process, involving psychogenic and hormonal input, and a neurovascular nonadrenergic, noncholinergic mechanism(3).
Dr. Murphy LL and Lee TJ. at the Southern Illinois University, School of Medicine, told PubMed, "Treatment with American ginseng also affects the central nervous system and has been shown to significantly alter the activity of hypothalamic catecholamines involved in the facilitation of copulatory behavior and hormone secretion"(3)
In 30 male rats randomly allocated into three groups of 10 rats each: 1. controls, 2. diabetes (D) and 3. diabetes + ginseng (DG) study, oral administration of ginseng extract showed a significant improvement of fertility parameters and testicular antioxidants together with a decrease in malondialdehyde, production of lipid peroxidation and prostaglandin biosynthesis and testicular pathological signs including degenerative changes of the seminiferous tubules(4). In infertile women with Polycystic ovarian syndrome (PCOS), Korean red ginseng extract (KRGE), lowered the high numbers of antral follicles and increased the number of corpora lutea in the polycystic ovaries(6).
Ginseng is a slow-growing perennial plants with fleshy roots, the genus Panax, belonging to the family Araliaceae. Depending to the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root).
The Asian herb has been used in traditional and Chinese medicine to promote yang and to improve cardiac function, short of breath, blood pressure. Panax ginseng can generates fluids and reduce thirst, to treat anxiety, insomnia, dizziness/headache, forgetfulness, impotence, diabetes, bleeding in the vagina not during period, etc.
The composition of carnitine, acetyl carnitine, L-arginine and ginseng in treatment of men with asthenopermia promoted the improvement of sperm motility and enhanced libido and sexual performance(7).
Its nutrients and chemical constituents including koryoginsenoside, ginsenoside, ginseng saponins, ginseng oils and phytosterol(4), carbohydrates and sugars, organic acids, nitrogenous substances, amino acids and peptides, vitamins and minerals(5), may hold the power of enhancing immunity through stimulating antiviral cytokine IFN-γ production, improved survival of human lung epithelial cells upon influenza virus infection, vascular dysfunctions, such as hypertension, atherosclerotic disorders and ischemic injury, etc.(8) These findings with the diverse pharmacological activities may be the reasons for ginseng to be named the king of all herbs in improved general well-being.
Taken altogether, ginseng, especially Panax ginseng and its major chemical compound ginsenosides
may be effective in enhancing the chance of fertility in both sexes, through vary mechanisms. Overdoses may cause nausea, diarrhea, high blood pressure, low blood pressure, breast pain, tremors, nervousness, headache, vomiting, insomnia, nose bleeding, etc.. As always, all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & related field specialist before applying.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Ginseng and male reproductive function by Wah Leung K, Wong AS.(PubMed)
(2) The role of nitric oxide in erectile dysfunction: implications for medical therapy by Burnett AL.(PubMed)
(3) Ginseng, sex behavior, and nitric oxide by Murphy LL, Lee TJ.(PubMed)
(4) Effect of ginseng extract supplementation on testicular functions in diabetic rats by Sawiress FA, Ziada MS, Bebawy WS, Amer HA.(PubMed)
(5) The chemical constituents of ginseng plants by Hou JP.(PubMed)
(6) Therapeutic effect of korean red ginseng extract on infertility caused by polycystic ovaries by Jung JH, Park HT, Kim T, Jeong MJ, Lim SC, Nah SY, Cho IH, Park SH, Kang SS, Moon CJ, Kim JC, Kim SH, Bae CS.(PubMed)
(7) [Treatment with carnitine, acetyl carnitine, L-arginine and ginseng improves sperm motility and sexual health in men with asthenopermia].[Article in Italian] by Morgante G, Scolaro V, Tosti C, Di Sabatino A, Piomboni P, De Leo V.(PubMed)
(8) Immunomodulatory activity of red ginseng against influenza A virus infection by Lee JS, Hwang HS2, Ko EJ3, Lee YN4, Kwon YM5, Kim MC6, Kang SM(PubMed)
(9)Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides by Yue PY, Mak NK, Cheng YK, Leung KW, Ng TB, Fan DT, Yeung HW, Wong RN(PubMed)
(10) Popular Herbs - Ginseng, Asian (Panax ginseng) and Ginseng, North America by Kyle J. Norton
Ginseng, the King of Chinese herb, according to the literature in Chinese medicine may be the next single herb in enhancing fertility in both sexes. According to the statistic from Centers for Disease Control and Prevention (CDC), approximately 7.3 million women of childbearing age (between 15 and 44) in the US are likely to have impaired fecundity with 11% of population in the US alone were infertile.
Beside improving general well-being, the herb has been used in traditional Chinese medicine to treat sexual dysfunction as well as enhanced sexual behavior(1).
Recent animal studies and confirmed in human case control studies, ginseng had shown a positive effects in enhancing libido, and copulatory performances(1). Ginsenosides, an active chemical compound extracted from ginseng was found not only to improve the sperm quality and count of healthy individuals and patients with treatment-related infertility(2), but also facilitate penile erection through directly inducing the vasodilatation and relaxation of penile corpus cavernosum(3).
In treatment of sexual dysfunction, ginsenoside also induced Nitric oxide (NO) function in the process, involving psychogenic and hormonal input, and a neurovascular nonadrenergic, noncholinergic mechanism(3).
Dr. Murphy LL and Lee TJ. at the Southern Illinois University, School of Medicine, told PubMed, "Treatment with American ginseng also affects the central nervous system and has been shown to significantly alter the activity of hypothalamic catecholamines involved in the facilitation of copulatory behavior and hormone secretion"(3)
In 30 male rats randomly allocated into three groups of 10 rats each: 1. controls, 2. diabetes (D) and 3. diabetes + ginseng (DG) study, oral administration of ginseng extract showed a significant improvement of fertility parameters and testicular antioxidants together with a decrease in malondialdehyde, production of lipid peroxidation and prostaglandin biosynthesis and testicular pathological signs including degenerative changes of the seminiferous tubules(4). In infertile women with Polycystic ovarian syndrome (PCOS), Korean red ginseng extract (KRGE), lowered the high numbers of antral follicles and increased the number of corpora lutea in the polycystic ovaries(6).
Ginseng is a slow-growing perennial plants with fleshy roots, the genus Panax, belonging to the family Araliaceae. Depending to the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root).
The Asian herb has been used in traditional and Chinese medicine to promote yang and to improve cardiac function, short of breath, blood pressure. Panax ginseng can generates fluids and reduce thirst, to treat anxiety, insomnia, dizziness/headache, forgetfulness, impotence, diabetes, bleeding in the vagina not during period, etc.
The composition of carnitine, acetyl carnitine, L-arginine and ginseng in treatment of men with asthenopermia promoted the improvement of sperm motility and enhanced libido and sexual performance(7).
Its nutrients and chemical constituents including koryoginsenoside, ginsenoside, ginseng saponins, ginseng oils and phytosterol(4), carbohydrates and sugars, organic acids, nitrogenous substances, amino acids and peptides, vitamins and minerals(5), may hold the power of enhancing immunity through stimulating antiviral cytokine IFN-γ production, improved survival of human lung epithelial cells upon influenza virus infection, vascular dysfunctions, such as hypertension, atherosclerotic disorders and ischemic injury, etc.(8) These findings with the diverse pharmacological activities may be the reasons for ginseng to be named the king of all herbs in improved general well-being.
Taken altogether, ginseng, especially Panax ginseng and its major chemical compound ginsenosides
may be effective in enhancing the chance of fertility in both sexes, through vary mechanisms. Overdoses may cause nausea, diarrhea, high blood pressure, low blood pressure, breast pain, tremors, nervousness, headache, vomiting, insomnia, nose bleeding, etc.. As always, all articles written by Kyle J. Norton are for information & education only, please consult your Doctor & related field specialist before applying.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Ginseng and male reproductive function by Wah Leung K, Wong AS.(PubMed)
(2) The role of nitric oxide in erectile dysfunction: implications for medical therapy by Burnett AL.(PubMed)
(3) Ginseng, sex behavior, and nitric oxide by Murphy LL, Lee TJ.(PubMed)
(4) Effect of ginseng extract supplementation on testicular functions in diabetic rats by Sawiress FA, Ziada MS, Bebawy WS, Amer HA.(PubMed)
(5) The chemical constituents of ginseng plants by Hou JP.(PubMed)
(6) Therapeutic effect of korean red ginseng extract on infertility caused by polycystic ovaries by Jung JH, Park HT, Kim T, Jeong MJ, Lim SC, Nah SY, Cho IH, Park SH, Kang SS, Moon CJ, Kim JC, Kim SH, Bae CS.(PubMed)
(7) [Treatment with carnitine, acetyl carnitine, L-arginine and ginseng improves sperm motility and sexual health in men with asthenopermia].[Article in Italian] by Morgante G, Scolaro V, Tosti C, Di Sabatino A, Piomboni P, De Leo V.(PubMed)
(8) Immunomodulatory activity of red ginseng against influenza A virus infection by Lee JS, Hwang HS2, Ko EJ3, Lee YN4, Kwon YM5, Kim MC6, Kang SM(PubMed)
(9)Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides by Yue PY, Mak NK, Cheng YK, Leung KW, Ng TB, Fan DT, Yeung HW, Wong RN(PubMed)
(10) Popular Herbs - Ginseng, Asian (Panax ginseng) and Ginseng, North America by Kyle J. Norton
Simple recipe - Bacon and egg muffin
4 Ingredients by Kim McCosker and Rachael Bermingham (Atria Books)
Serve 1
A recipe from Brett McCosker
1 egg
1 slice bacon
1 English muffin
1 tsp. barbecue sauce
Ina small skillet, fry egg and bacon, drain on paper towels. Toast muffin a toaster, spread with barbecue sauce and top with bacon and egg.
Optional: add a slice of cheese.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
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Salad recipe - Lettuce tomato
Contributed by Company Coming salads by Jean Pare
A pretty salad to brighten appetites
1/4 lettuce, solid medium head
2-3 green onions, chopped
1-2 tomatoes, cut into small chunks
1/4 to 1/2 cup (50-125 ml) salad dressing (or mayonnaise) to coat
Cut a tear lettuce into bite size pieces in a salad bowl. Add green onions. Add tomatoes just before serving as not dilute dressing. Add salad dressing. Toss to coat. Serve 4.
5. Spinach salad(Company Coming salads by Jean Pare)
Not the usual spinach salad. Different and tastier.
Dressing
1/2 cup (125 ml) salad dressing (or mayonnaise)
1/4 cup (60 ml) commercial coleslaw dressing
1/4 tsp. (1 ml) dill weed
Salad
6 cups (1.5 ml) spinach leaves, torn and lightly packed
1/4 cups (60 ml) grated Swiss cheese
1 cup (250 ml) fresh sliced mushrooms
6 bacon slice, cooked and crumbled
2. hard- boiled eggs, chopped
Dressing: Combined all 3 ingredients in a small bowl. Stir. Set aside.
salad: Place spinach in a large bowl. Add about 3/4 dressing. Toss to coat. pile onto 4 to 6sald plates
Sprinkle Swiss cheese over top. Sprinkle with mushrooms, bacon and egg. Drizzle remaining dressing over top. Serve immediately. Serve 4 to 6.
Variation: Swiss cheese may be omitted. Double amount of Cheddar for equally good results.
Romaine salad: substitute Romaine lettuce for spinach leaves. Delicious and easier to obtain at time than spinach.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
A pretty salad to brighten appetites
1/4 lettuce, solid medium head
2-3 green onions, chopped
1-2 tomatoes, cut into small chunks
1/4 to 1/2 cup (50-125 ml) salad dressing (or mayonnaise) to coat
Cut a tear lettuce into bite size pieces in a salad bowl. Add green onions. Add tomatoes just before serving as not dilute dressing. Add salad dressing. Toss to coat. Serve 4.
5. Spinach salad(Company Coming salads by Jean Pare)
Not the usual spinach salad. Different and tastier.
Dressing
1/2 cup (125 ml) salad dressing (or mayonnaise)
1/4 cup (60 ml) commercial coleslaw dressing
1/4 tsp. (1 ml) dill weed
Salad
6 cups (1.5 ml) spinach leaves, torn and lightly packed
1/4 cups (60 ml) grated Swiss cheese
1 cup (250 ml) fresh sliced mushrooms
6 bacon slice, cooked and crumbled
2. hard- boiled eggs, chopped
Dressing: Combined all 3 ingredients in a small bowl. Stir. Set aside.
salad: Place spinach in a large bowl. Add about 3/4 dressing. Toss to coat. pile onto 4 to 6sald plates
Sprinkle Swiss cheese over top. Sprinkle with mushrooms, bacon and egg. Drizzle remaining dressing over top. Serve immediately. Serve 4 to 6.
Variation: Swiss cheese may be omitted. Double amount of Cheddar for equally good results.
Romaine salad: substitute Romaine lettuce for spinach leaves. Delicious and easier to obtain at time than spinach.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Monday, 28 April 2014
Cervical cancer in Folate Points of View
Kyle J. Norton
According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of 4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(1).
Folate, also known as folic acid, vitamin B9, is a water soluble vitamin, found abundantly in leafy vegetables, citrus fruits, beans, whole grain, etc. The vitamin plays an important role in synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions, production of red blood cells for anemia prevention.
Epidemiological studies focusing folate or vitamin B9 in reduced risk of cervical cancer have produced conflict results(a)(b)(c)(d).
Levels of serum of folate
Suggestion of lower levels of serum of folate or deficiency of folate and vitamin B12 may induce risk of cervical caner. According to a case-control study enrolled 927 Korean women (440 controls, 165 patients with CIN 1, 167 patients with CIN 2/3, and 155 patients with cervical cancer, aged 20-75 years) study by Kyunghee University College of Medicine, serum of folate is associated to reduced risk of cervical cancer but MTHFR variant genotype may increase CIN and cervical cancer risk in women with low folate or vitamin B12 status(2). The Shanxi Medical University, in the study of the effects of folate against human cervical cancer cell line and HPV indicated that different concentration of folate inhibited cervical cancer cell proliferation and enhanced cell apoptosis, but not interaction between folate and HPV16 in cervical cancer cell(3). Also, in regard of serum folate, vitamin B12, MTHFR polymorphisms and serum homocysteine (chemiluminescence assay) among 322 women from Kerala, South India, found that no significant associations between MTHFR polymorphisms, serum homocysteine, and folate levels with cervical carcinogenesis but these parameters acted as effect modifiers of serum vitamin B12, implicating a synergistic role of these 2 vitamins in invasive cervical cancer(4). Other suggestion of high-expression of DNMT1 protein or mRNA and folate deficiency was significantly associated with cervical carcinogenesis(5) and adequate folate could effectively inhibit the proliferation of cervical cancer cells and facilitate their apoptosis in vitro, thus would reverse the aberration protein expression of DNMT1 and MeCP2(6).
The effects
The All India Institute of Medical Sciences,study, alood and tissue samples collected from normal (n = 35), SILs (n = 27), and cervical cancer patients (n = 38) in the age group of 26-70 years, indicated a role of folate and vitamin B(12) in modulating the risk of cervical cancer(7). Women with higher concentrations of serum folate and vitamin B12 may have a beneficial impact on the prevention of CC. and a lower risk of being positive for HR-HPVs, according to the University of Alabama at Birmingham (UAB)(8). Other researchers suggested that low levels of folate might increase the risk of cervical cancer, and there may be a potential interaction between low level of serum folate and HPV16 in the development of cervical cancer(9) and Improved folate status in people who are at risk of getting infected or already infected with high-risk HPV may have a beneficial impact in the prevention of cervical cancer(9). IGFBP3, insulin-like growth factor binding protein 3, decreased associated to the progression of cervical cancer, folic acid increased levels of IGF-BP3, of that lead to inhibition of cervical cancer cell growth(10).
Taking altogether, serum concentration of folate is associated to reduced risk and treatment of cervical cancer and supplement folate may improve people who are at risk of cervical due to HPV infection.
Over doses of folate may induce symptoms of difficulty of coordinating movement, numbness, sensory changes, etc., please make sure you follow the guideline of the Institute of Medicine of the National Academies.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Cerical cancer (Amerrican cancer society)
(a) Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin, and vitamin B12 by Hernandez BY1, McDuffie K, Wilkens LR, Kamemoto L, Goodman MT.(PubMed)
(b) A case control study of nutritional factors and cervical dysplasia by Liu T1, Soong SJ, Wilson NP, Craig CB, Cole P, Macaluso M, Butterworth CE Jr.(PubMed)
(c) [Chemoprevention of cervical cancer--intervention study of cervical precancerous lesions by retinamide II and riboflavin].[Article in Chinese] byChen RD.(PubMed)
(d) Epidemiologic studies of vitamins and cancer of the lung, esophagus, and cervix by Ziegler RG.(PubMed)
(2) Common polymorphisms in methylenetetrahydrofolate reductase gene are associated with risks of cervical intraepithelial neoplasia and cervical cancer in women with low serum folate and vitamin B12 by Tong SY1, Kim MK, Lee JK, Lee JM, Choi SW, Friso S, Song ES, Lee KB, Lee JP.(PubMed)
(3) [Effect of folate on the proliferation of human cervical cancer cell and relationship with HPV16].
(4) A case-control nutrigenomic study on the synergistic activity of folate and vitamin B12 in cervical cancer progression by Ragasudha PN1, Thulaseedharan JV, Wesley R, Jayaprakash PG, Lalitha P, Pillai MR.(PubMed)
(5) Folate deficiency and aberrant expression of DNA methyltransferase 1 were associated with cervical cancerization by Jin-Tao W1, Ling D, Shi-Wen J, Junxia H, Wei-Min Z, Qin Z, Zuo-Kai Y, Li Z.(PubMed)
(6) [Effect of folate in modulating the expression of DNA methyltransferase 1 and methyl-CpG-bingding protein 2 in cervical cancer cell lines].
According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of 4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(1).
Folate, also known as folic acid, vitamin B9, is a water soluble vitamin, found abundantly in leafy vegetables, citrus fruits, beans, whole grain, etc. The vitamin plays an important role in synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions, production of red blood cells for anemia prevention.
Epidemiological studies focusing folate or vitamin B9 in reduced risk of cervical cancer have produced conflict results(a)(b)(c)(d).
Levels of serum of folate
Suggestion of lower levels of serum of folate or deficiency of folate and vitamin B12 may induce risk of cervical caner. According to a case-control study enrolled 927 Korean women (440 controls, 165 patients with CIN 1, 167 patients with CIN 2/3, and 155 patients with cervical cancer, aged 20-75 years) study by Kyunghee University College of Medicine, serum of folate is associated to reduced risk of cervical cancer but MTHFR variant genotype may increase CIN and cervical cancer risk in women with low folate or vitamin B12 status(2). The Shanxi Medical University, in the study of the effects of folate against human cervical cancer cell line and HPV indicated that different concentration of folate inhibited cervical cancer cell proliferation and enhanced cell apoptosis, but not interaction between folate and HPV16 in cervical cancer cell(3). Also, in regard of serum folate, vitamin B12, MTHFR polymorphisms and serum homocysteine (chemiluminescence assay) among 322 women from Kerala, South India, found that no significant associations between MTHFR polymorphisms, serum homocysteine, and folate levels with cervical carcinogenesis but these parameters acted as effect modifiers of serum vitamin B12, implicating a synergistic role of these 2 vitamins in invasive cervical cancer(4). Other suggestion of high-expression of DNMT1 protein or mRNA and folate deficiency was significantly associated with cervical carcinogenesis(5) and adequate folate could effectively inhibit the proliferation of cervical cancer cells and facilitate their apoptosis in vitro, thus would reverse the aberration protein expression of DNMT1 and MeCP2(6).
The effects
The All India Institute of Medical Sciences,study, alood and tissue samples collected from normal (n = 35), SILs (n = 27), and cervical cancer patients (n = 38) in the age group of 26-70 years, indicated a role of folate and vitamin B(12) in modulating the risk of cervical cancer(7). Women with higher concentrations of serum folate and vitamin B12 may have a beneficial impact on the prevention of CC. and a lower risk of being positive for HR-HPVs, according to the University of Alabama at Birmingham (UAB)(8). Other researchers suggested that low levels of folate might increase the risk of cervical cancer, and there may be a potential interaction between low level of serum folate and HPV16 in the development of cervical cancer(9) and Improved folate status in people who are at risk of getting infected or already infected with high-risk HPV may have a beneficial impact in the prevention of cervical cancer(9). IGFBP3, insulin-like growth factor binding protein 3, decreased associated to the progression of cervical cancer, folic acid increased levels of IGF-BP3, of that lead to inhibition of cervical cancer cell growth(10).
Taking altogether, serum concentration of folate is associated to reduced risk and treatment of cervical cancer and supplement folate may improve people who are at risk of cervical due to HPV infection.
Over doses of folate may induce symptoms of difficulty of coordinating movement, numbness, sensory changes, etc., please make sure you follow the guideline of the Institute of Medicine of the National Academies.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Cerical cancer (Amerrican cancer society)
(a) Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin, and vitamin B12 by Hernandez BY1, McDuffie K, Wilkens LR, Kamemoto L, Goodman MT.(PubMed)
(b) A case control study of nutritional factors and cervical dysplasia by Liu T1, Soong SJ, Wilson NP, Craig CB, Cole P, Macaluso M, Butterworth CE Jr.(PubMed)
(c) [Chemoprevention of cervical cancer--intervention study of cervical precancerous lesions by retinamide II and riboflavin].[Article in Chinese] byChen RD.(PubMed)
(d) Epidemiologic studies of vitamins and cancer of the lung, esophagus, and cervix by Ziegler RG.(PubMed)
(2) Common polymorphisms in methylenetetrahydrofolate reductase gene are associated with risks of cervical intraepithelial neoplasia and cervical cancer in women with low serum folate and vitamin B12 by Tong SY1, Kim MK, Lee JK, Lee JM, Choi SW, Friso S, Song ES, Lee KB, Lee JP.(PubMed)
(3) [Effect of folate on the proliferation of human cervical cancer cell and relationship with HPV16].
[Article in Chinese] by Ding L1, Ma J, Zhou Q, Wang J.(PubMed)
(4) A case-control nutrigenomic study on the synergistic activity of folate and vitamin B12 in cervical cancer progression by Ragasudha PN1, Thulaseedharan JV, Wesley R, Jayaprakash PG, Lalitha P, Pillai MR.(PubMed)
(5) Folate deficiency and aberrant expression of DNA methyltransferase 1 were associated with cervical cancerization by Jin-Tao W1, Ling D, Shi-Wen J, Junxia H, Wei-Min Z, Qin Z, Zuo-Kai Y, Li Z.(PubMed)
(6) [Effect of folate in modulating the expression of DNA methyltransferase 1 and methyl-CpG-bingding protein 2 in cervical cancer cell lines].
[Article in Chinese]by Wang JT1, Wu TT, Bai L, Ding L, Hao M, Wang Y.(PubMed)
(7) Cervical cancer pathogenesis is associated with one-carbon metabolism by Pathak S1, Bhatla N, Singh N(PubMed)
(8) Indian women with higher serum concentrations of folate
and vitamin B12 are significantly less likely to be infected with
carcinogenic or high-risk (HR) types of human papillomaviruses (HPVs) by Piyathilake CJ1, Badiga S, Paul P, Vijayaraghavan K, Vedantham H, Sudula M, Sowjanya P, Ramakrishna G, Shah KV, Partridge EE, Gravitt PE.(PubMed)
(9) Folate is associated with the natural history of high-risk human papillomaviruses by Piyathilake CJ1, Henao OL, Macaluso M, Cornwell PE, Meleth S, Heimburger DC, Partridge EE.(PubMed)
(10) In vitro downregulation of growth factors by insulin-like growth factor binding protein-3 in cervical cancer. by Mathur RS1, Mathur SP.(PubMed)
Peasant soup
The vegetarian collection by Alison Kent and Canadian living test Chicken
Prep. 10 minutes, cook 15 minutes, make 6 serving
2 tbsp. (30 ml) vegetable oil
3 stacks celery, diced
2 carrots, diced
1 onion, diced
5 cloves garlic, minced
1/2 tsp. (2ml) salt
1/2 tsp. (2ml) dried mint
1/4 tsp. (1ml) turmeric
1 can (28 oz./796 ml) whole tomatoes
1/3 cup (75 ml) dried green lentils, rinsed and drained
1 tbsp. (15 ml) tomato paste
1/2 cup (125 ml) mini shell pasta
1 can (19 oz./ 540 ml) bean medley, drained and rinsed
2 tbsp. (30 ml) chopped fresh parsley
In large saucepan or Dutch oven, heat oil over medium heat, fry celery, carrots, onion, garlic salt mint, turmeric, stirring occasionally until softened about 6 minutes.
Stir in tomatoes, breaking up with back of spoon; stir in lentils, tomato paste and 41/2 cups (1125ml) water. Bring to boil, reduced heat and simmer. covered until lentils are tender about 25 minutes.
Meanwhile, in large pot of boiling salted water, cook pasta until al dente, about 8 minutes. Drain and add to soup along with beans and parsley; simmer for 5 minutes.(16).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Prep. 10 minutes, cook 15 minutes, make 6 serving
2 tbsp. (30 ml) vegetable oil
3 stacks celery, diced
2 carrots, diced
1 onion, diced
5 cloves garlic, minced
1/2 tsp. (2ml) salt
1/2 tsp. (2ml) dried mint
1/4 tsp. (1ml) turmeric
1 can (28 oz./796 ml) whole tomatoes
1/3 cup (75 ml) dried green lentils, rinsed and drained
1 tbsp. (15 ml) tomato paste
1/2 cup (125 ml) mini shell pasta
1 can (19 oz./ 540 ml) bean medley, drained and rinsed
2 tbsp. (30 ml) chopped fresh parsley
In large saucepan or Dutch oven, heat oil over medium heat, fry celery, carrots, onion, garlic salt mint, turmeric, stirring occasionally until softened about 6 minutes.
Stir in tomatoes, breaking up with back of spoon; stir in lentils, tomato paste and 41/2 cups (1125ml) water. Bring to boil, reduced heat and simmer. covered until lentils are tender about 25 minutes.
Meanwhile, in large pot of boiling salted water, cook pasta until al dente, about 8 minutes. Drain and add to soup along with beans and parsley; simmer for 5 minutes.(16).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Researched articles - Points of view of Vitamins, Foods and Herbs http://kylejnorton.blogspot.ca/p/blog-page_24.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
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