A. Obesity is defined as a medical condition of excess
body fat has accumulated overtime, while overweight is a condition
of excess body weight relatively to the height. According to the
Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over
weight, while a BMI of over 30 is an indication of obesity.
According to the statistic, 68% of American population are either
overweight or obese.
B. How to calculate your BMI index
BMI= weight (kg)/ height (m2)
C. Stroke
Besides
cancer and heart diseases, stroke is the third leading cause of death.
Approximate 1/4 of all stroke victims die as a direct result of the
stroke or it's complications. Stroke is caused by uncontrolled diet
that is high in saturated and trans fats resulting in cholesterol build
up in the arteries and high blood pressure. In other words, if
cholesterol building up in the arteries is blocking the circulation of
blood in any part of the body causing oxygen not to be delivered to the
brain, resulting in some cells in the brain to die off and are unable
reproduce, then we have stroke. Other strokes happen when a blood vessel
in the brain ruptures causing the cells in your brain to be deprived
of oxygen in your blood, they die and never come back.
D. How Obesity associates with Stroke
1. In a study of "Evaluation of the Obesity Genes FTO and MC4R and the Type 2 Diabetes Mellitus Gene TCF7L2 for Contribution to Stroke Risk: The Mannheim-Heidelberg Stroke Study"
by Winter Y, Back T, Scherag A, Linseisen J, Rohrmann S, Lanczik O,
Hinney A, Scherag S, Neumaier M, Ringleb PA, Dodel R, Hebebrand J.,
posted in PubMed, researchers found that the observed trends of obesity risk alleles for risk of stroke/TIA
as well as the possible sex-specific differences in clinical outcomes
found for the TCF7L2 (rs7903146) require replication in future studies.
Our study demonstrates that candidate gene studies for common stroke may benefit from focusing on polymorphisms that predispose to vascular risk.
2. According to the study of "Trends in stroke hospitalizations and associated risk factors among children and young adults, 1995-2008" by George MG, Tong X, Kuklina EV, Labarthe DR., posted in PubMed, researchers wrote that During the period of study, the prevalence of hospitalizations of acute ischemic stroke
increased among all age and gender groups except females aged 5 to 14
years. Females aged 15 to 34 years and males and females aged 35 to 44
years showed a decrease in the prevalence of hospitalizations for
subarachnoid hemorrhage, whereas females aged 5 to 14 years showed
increases for subarachnoid hemorrhage. Hypertension, diabetes, obesity,
lipid disorders, and tobacco use were among the most common coexisting
conditions, and their prevalence increased from 1995 to 2008 among
adolescents and young adults (aged 15-44 years) hospitalized with acute
ischemic stroke.
3. In the study of "Weight of the obesity epidemic: rising stroke rates among middle-aged women in the United States" by Towfighi A, Zheng L, Ovbiagele B., posted in PubMed, researchers found that Stroke
prevalence among women aged 35 to 54 years has tripled over the past 2
decades, at the same time remaining stable among men. Prevalence of obesity and 3 metabolic syndrome components increased; they may be key factors in the increase in women's stroke prevalence.
4. According to the study of "Health and economic burden of the projected obesity trends in the USA and the UK" by Wang YC, McPherson K, Marsh T, Gortmaker SL, Brown M., posted in PubMed,
researchers wrote that These trends project 65 million more obese
adults in the USA and 11 million more obese adults in the UK by 2030,
consequently accruing an additional 6-8·5 million cases of diabetes,
5·7-7·3 million cases of heart disease and stroke, 492,000-669,000 additional cases of cancer, and 26-55 million quality-adjusted life years forgone for USA and UK combined.
5. In a study of "Prevalence of overweight and obesity in the United States, 1999-2004" by Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM., posted in PubMed, researchers found that The prevalence of overweight among children and adolescents and obesity
among men increased significantly during the 6-year period from 1999
to 2004; among women, no overall increases in the prevalence of obesity
were observed. These estimates were based on a 6-year period and
suggest that the increases in body weight are continuing in men and in
children and adolescents while they may be leveling off in women.
6. Etc.
E. Treatments of Obesity and Stroke
1. Accoesing to the abstract of the study of `Targeting the melanocortin receptor system for anti-stroke therapy` by Holloway PM, Smith HK, Renshaw D, Flower RJ, Getting SJ, Gavins FN., posted in PubMed, researchers indicated that Stroke continues to be a leading cause of death worldwide, with risk factors including smoking, diabetes, hypertension and obesity. The pathophysiology of stroke
is highly complex: reintroduction of blood flow to the infarcted brain
region is paramount in limiting ischaemic damage caused by stroke, yet a concomitant inflammatory response can compound tissue damage. The possibilities of pro-resolving treatments
that target this inflammatory response have only recently begun to be
explored. This review discusses the endogenous roles of the
melanocortin system in reducing characterized aspects of inflammation,
and how these, together with potent neuroprotective actions, suggest
its potential as a therapeutic target in stroke.
2. In a study of `Preventing increased blood pressure in the obese Zucker rat improves severity of stroke`by Osmond JM, Mintz JD, Stepp DW., posted in PubMed,
researchers wrote that Cerebral ischemia was induced for 60 min using
an intralumenal suture technique, followed by 24 h of reperfusion. HCT
treatment effectively prevented the increase in blood pressure in obese
rats; however, the LS diet did not lower pressure. Importantly,
infarct size was normalized by HCT after ischemia-reperfusion injury.
Additionally, HCT improved the changes in MCA structure observed in
untreated OZRs. There were no benefits of the LS diet on stroke
injury or vessel structure. These results indicate that increased
pressure is essential for driving the changes in infarct size in OZRs.
3. According to the study of `Three-month exercise and weight loss program improves heart rate recovery in obese persons along with cardiopulmonary function`by
Nagashima J, Musha H, Takada H, Takagi K, Mita T, Mochida T, Yoshihisa
T, Imagawa Y, Matsumoto N, Ishige N, Fujimaki R, Nakajima H, Murayama
M., posted in PubMed,
researchers found that Our data demonstrated that HRR can be improved
in obese subjects by a 3-month exercise and weight loss program.
Improvement in cardiopulmonary function by exercise seems to be the
main contributor to the increment of HRR.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sunday, 3 November 2013
Obesity and Carpal Tunnel Syndrome
A. Obesity is defined as a medical condition of excess
body fat has accumulated overtime, while overweight is a condition of
excess body weight relatively to the height. According to the Body
Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight,
while a BMI of over 30 is an indication of obesity. According to the
statistic, 68% of American population are either overweight or obese.
B. How do calculate your BMI index
BMI= weight (kg)/ height (m2)
C. Carpal Tunnel Syndrome is defined as a condition of numbness, tingling, weakness, or muscle damage in the hand and fingers, as a result of the pressure on the median nerve.
D. How Obesity associates Carpal Tunnel Syndrome
1. According to the study of|The relationship of obesity, age, and carpal tunnel syndrome: more complex than was thought?" by Bland JD., posted in PubMed, researchers found that increased BMI is a significant independent risk factor for CTS in patients under the age of 63 years, but is less important in older patients. Patients over the age of 63 years have a different pattern of risk factors for CTS than younger patients. This suggests that CTS in the elderly population may have different underlying pathogenetic mechanisms.
2. In study of "Carpal tunnel syndrome" by Aroori S, Spence RA., posted in PubMed, researchers indicated that Carpal tunnel syndrome is one of the most common peripheral neuropathies. It affects mainly middle aged women. In the majority of patients the exact cause and pathogenesis of CTS is unclear. Although several occupations have been linked to increased incidence and prevalence of CTS the evidence is not clear. Occupational CTS is uncommon and it is essential to exclude all other causes particularly the intrinsic factors such as obesity before attributing it to occupation.
3. According to the study of "Hand syndromes associated with diabetes: impairments and obesity predict disability" by Redmond CL, Bain GI, Laslett LL, McNeil JD., posted in PubMed, researchers found that In adults with hand syndromes associated with diabetes, disability was related to impaired muscle function and carpal tunnel syndrome. Obesity and overall physical functioning influenced hand disability, particularly in women.
4. In abstract of the study of "Assessment of body mass index and hand anthropometric measurements as independent risk factors for carpal tunnel syndrome" by Sharifi-Mollayousefi A, Yazdchi-Marandi M, Ayramlou H, Heidari P, Salavati A, Zarrintan S, Sharifi-Mollayousefi A., posted in PubMed, researchers found that The mean values of BMI, wrist ratio and shape index were significantly higher in all CTS patients and females compared to controls, whereas in males only BMI and wrist ratio were higher. The patients in the mild severity subgroup had a significantly lower age and wrist ratio. BMI, wrist ratio and shape index were found to be independent risk factors of CTS development in all patients and females. Our study showed BMI, wrist ratio and shape index as independent risk factors for CTS. These findings are of potential anatomical and clinical importance and outline the risk factors of anatomical malfunction of the wrist in CTS.
5. According to the study of "Individual risk factors for carpal tunnel syndrome: an evaluation of body mass index, wrist index and hand anthropometric measurements" by Boz C, Ozmenoglu M, Altunayoglu V, Velioglu S, Alioglu Z., posted in PubMed, researchers concluded that Differences in the hand length/height ratio were not statistically significant in female and male CTS patients compared to their controls and it was not found to be an independent risk factor for CTS. Our study confirmed BMI as an independent risk factor for CTS in both genders. Hand and wrist anthropometrics were found to be independent risk factors for CTS in females, but not in males.
6. In abstract of the study of "Epidemiology of carpal tunnel syndrome in women of childbearing age. Findings in a large cohort study" by Vessey MP, Villard-Mackintosh L, Yeates D., posted in PubMed, researchers indicated that The most significant positive association between an existing disease and CTS was menstrual disorders (p=.001). Additional similar associations existed for orthopedic conditions and gastrointestinal tract symptoms. The relationships between CTS and OC use, menstrual disorders, and obesity may be related to pressure on the median nerve due to fat or edema near the carpal tunnel.
7. Etc.
E. Treatments of Obesity and Carpal Tunnel Syndrome
1. According to the study of "Medical and non-medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million" by Tseng CH, Liao CC, Kuo CM, Sung FC, Hsieh DP, Tsai CH., posted in PubMed, researchers found that Patients were predominantly women (65.6% vs. 47.7% in the control group) and older (40 and above, 62.6% vs. 36.2%). Rheumatoid arthritis was found to be the most significant comorbidity associated with CTS, followed by gout, hypertension, diabetes, obesity, uremia, and acromegaly. For younger group age ≤39, the association of these comorbidities was stronger, and hypothyroidism and vitamin B(6) deficiency were additional comorbidities...., these disorders may aid in removing possible causes of CTS. This is the first report on the effect of aging on probable CTS risk factors. How factors associated with aging contribute to the development of CTS remains to be determined.
2. In a study of "Concurrent medical disease in work-related carpal tunnel syndrome" by, Atcheson SG, Ward JR, Lowe W., posted in PubMed, researchers concluded that Routine patient histories and record reviews are inadequate for proper evaluation of work-related CTS. Unrecognized medical diseases capable of causing CTS are common. Studies asserting an association between occupational hand usage and CTS are of questionable validity unless they prospectively account for confounding disease and obesity.
3. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
B. How do calculate your BMI index
BMI= weight (kg)/ height (m2)
C. Carpal Tunnel Syndrome is defined as a condition of numbness, tingling, weakness, or muscle damage in the hand and fingers, as a result of the pressure on the median nerve.
D. How Obesity associates Carpal Tunnel Syndrome
1. According to the study of|The relationship of obesity, age, and carpal tunnel syndrome: more complex than was thought?" by Bland JD., posted in PubMed, researchers found that increased BMI is a significant independent risk factor for CTS in patients under the age of 63 years, but is less important in older patients. Patients over the age of 63 years have a different pattern of risk factors for CTS than younger patients. This suggests that CTS in the elderly population may have different underlying pathogenetic mechanisms.
2. In study of "Carpal tunnel syndrome" by Aroori S, Spence RA., posted in PubMed, researchers indicated that Carpal tunnel syndrome is one of the most common peripheral neuropathies. It affects mainly middle aged women. In the majority of patients the exact cause and pathogenesis of CTS is unclear. Although several occupations have been linked to increased incidence and prevalence of CTS the evidence is not clear. Occupational CTS is uncommon and it is essential to exclude all other causes particularly the intrinsic factors such as obesity before attributing it to occupation.
3. According to the study of "Hand syndromes associated with diabetes: impairments and obesity predict disability" by Redmond CL, Bain GI, Laslett LL, McNeil JD., posted in PubMed, researchers found that In adults with hand syndromes associated with diabetes, disability was related to impaired muscle function and carpal tunnel syndrome. Obesity and overall physical functioning influenced hand disability, particularly in women.
4. In abstract of the study of "Assessment of body mass index and hand anthropometric measurements as independent risk factors for carpal tunnel syndrome" by Sharifi-Mollayousefi A, Yazdchi-Marandi M, Ayramlou H, Heidari P, Salavati A, Zarrintan S, Sharifi-Mollayousefi A., posted in PubMed, researchers found that The mean values of BMI, wrist ratio and shape index were significantly higher in all CTS patients and females compared to controls, whereas in males only BMI and wrist ratio were higher. The patients in the mild severity subgroup had a significantly lower age and wrist ratio. BMI, wrist ratio and shape index were found to be independent risk factors of CTS development in all patients and females. Our study showed BMI, wrist ratio and shape index as independent risk factors for CTS. These findings are of potential anatomical and clinical importance and outline the risk factors of anatomical malfunction of the wrist in CTS.
5. According to the study of "Individual risk factors for carpal tunnel syndrome: an evaluation of body mass index, wrist index and hand anthropometric measurements" by Boz C, Ozmenoglu M, Altunayoglu V, Velioglu S, Alioglu Z., posted in PubMed, researchers concluded that Differences in the hand length/height ratio were not statistically significant in female and male CTS patients compared to their controls and it was not found to be an independent risk factor for CTS. Our study confirmed BMI as an independent risk factor for CTS in both genders. Hand and wrist anthropometrics were found to be independent risk factors for CTS in females, but not in males.
6. In abstract of the study of "Epidemiology of carpal tunnel syndrome in women of childbearing age. Findings in a large cohort study" by Vessey MP, Villard-Mackintosh L, Yeates D., posted in PubMed, researchers indicated that The most significant positive association between an existing disease and CTS was menstrual disorders (p=.001). Additional similar associations existed for orthopedic conditions and gastrointestinal tract symptoms. The relationships between CTS and OC use, menstrual disorders, and obesity may be related to pressure on the median nerve due to fat or edema near the carpal tunnel.
7. Etc.
E. Treatments of Obesity and Carpal Tunnel Syndrome
1. According to the study of "Medical and non-medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million" by Tseng CH, Liao CC, Kuo CM, Sung FC, Hsieh DP, Tsai CH., posted in PubMed, researchers found that Patients were predominantly women (65.6% vs. 47.7% in the control group) and older (40 and above, 62.6% vs. 36.2%). Rheumatoid arthritis was found to be the most significant comorbidity associated with CTS, followed by gout, hypertension, diabetes, obesity, uremia, and acromegaly. For younger group age ≤39, the association of these comorbidities was stronger, and hypothyroidism and vitamin B(6) deficiency were additional comorbidities...., these disorders may aid in removing possible causes of CTS. This is the first report on the effect of aging on probable CTS risk factors. How factors associated with aging contribute to the development of CTS remains to be determined.
2. In a study of "Concurrent medical disease in work-related carpal tunnel syndrome" by, Atcheson SG, Ward JR, Lowe W., posted in PubMed, researchers concluded that Routine patient histories and record reviews are inadequate for proper evaluation of work-related CTS. Unrecognized medical diseases capable of causing CTS are common. Studies asserting an association between occupational hand usage and CTS are of questionable validity unless they prospectively account for confounding disease and obesity.
3. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Obesity's Complications http://kylejnorton.blogspot.ca/p/obesitys-complications.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Allergies - House Dust Allergy
Allergy is the over reaction of immune system to harmless substances after entering our body affecting 1 in every 3 people.
Cure Allergies Completely Naturally
Allergy Free For Life All Natural Cure
For Stopping Your Allergies In 5 Days
Causes
Allergy is defined as the type I reactions or Immediate Hypersensitivity as a result ofover production of Immunoglobulin E (IgE), a class of allergic antibody by the immune system against harmless substance that lead to mediated release of histamine and other mediators from mast cells and basophils, resulting in allergic reaction, including mucus secretion, sneezing, itching, etc.
G. House dust Allergy is defined as a condition of fabnormal immune reaction as a result of dust exposure related to common household chores such as vacuuming, sweeping, and dusting.
G.1. A. 1. How to determine the severity of the allergic effects
Depending to the allergy stimulating effect, some researchers suggested to scale the severity from 1 to 4 and followed by degeneration scale, but from -1 to -4
G.1.1. The severity scale from +1 to +4
+1. The first level of stimulation
If there is no symptoms at all or If the patient is alert and function morally after allergic efects.
+2. The second level of stimulation
The patient have become irritable, hyperactive, tense, thirsty, etc. after a suspected allergic effects
+3. The third level of stimulation
The patient have become hypomanic, aggressive, apprehensive, etc.
+4. The fourth level of stimulation
The patient have become mania, agitation, over excitement, etc.
G.1.2. Degeneration scale from -1 to -4
-1. If a patient is experience symptoms of reaction of runny nose, hive, diarrhea, etc.
-2. If a patient is experience symptoms of reaction of tiredness, fatigue, swelling etc.
-3. If a patient is experience symptoms of reaction of depression, mental disturbance, confusion, mood change, etc.
-4. If a patient is experience symptoms of reaction of sever depression, paranoia, etc.
G.2. Symptoms
Symptoms of house dust allergy are the result of airway inflammation of which can affects the daily activity including quality of life, productivity, and other chronic conditions, including asthma.
In the study of "Characteristics of Young Atopic Adults with Self-Reported Past Wheeze and Airway Hyperresponsiveness" by Yoshikawa T, Kanazawa H. (Source from Department of Sports Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan) posted in PubMed, researchers raised that the possibility that self-reported past-wheezers with AHR might form a distinct subgroup with features similar to past-asthmatics, which is one of the risk groups for adult asthma.
and
1. Asthma-like symptoms
2. Itching
3. Sneezing
4. Wheezing
5. Sinus pain
6. Tearing eyes
7. Runny nose
8. Itchy eyes and throat
9. Etc.
G.3. Diagnosis
If you are experience Allergic Rhinitis, it is possible to find what types of allergen have trigger that. After recording the family history and a complete physical exam. you doctor may order
1. Skin test
a. Intradermal test
It is one of most common test but time consuming( some patient may return for more 20 time for the injection) in diagnosis of allergy and depending to the symptoms, by injecting small amounts of diluted allergens into the top layers of the skin to see how the immune system react to them.
b. Skin prick testing
Similar to the Intradermal test, but the diagnosis involves in applying a drop of allergen into to punctures made on the skin.
2. Blood test (RadioAllergoSorbent Test)
This is the test for evaluating of the levels of IgE-mediated food allergies react to a particular allergen. If you RAST score is higher than the predictive value for that food, 95% chance you will have an allergic reaction. Unfortunately, non-IgE mediated allergies cannot be detected by this method.
3. Challenge Tests
Because of the risk of anaphylaxis, most doctors will avoid the test unless it is absolutely necessary and the test is performed only in the hospital. In this test, suspected allergen package into capsule taken by patient and signs or symptoms of an allergic reaction are observed.
4. Etc.
G..4. Prevention
There is no way to prevent them unless you can prevent yourdelf from dust exposure related to common household chores such as vacuuming, sweeping, and dusting. But one can always enhance the immune system by eating healthy and living a healthy lifestyle. For more information of healthy foods, visit 100+ Healthy Foods Classification
Since Allergies are caused by immune over reaction of certain harmless substance, enhancing immue system is one of the best way to prevent and treat them as some researchers suggested that allergies may be caused by weakened immune system over aggression. Vitamin A, E, C are antioxidants and free radical scavengers, they protect the immune system from free radicals attack and help to reduce levels of histamine in the blood. For more information of antioxidants and health effects
G.5. Treatments
G.5.1. Conventional medicine
According to the "Treatment of allergic rhinitis." American Family Physician - Volume 81, Issue 12 (June 2010), posted in MD preview, the writer wrote that allergic rhinitis is a common chronic respiratory illness that affects quality of life, productivity, and other comorbid conditions, including asthma. Treatment should be based on the patient's age and severity of symptoms. Patients should be advised to avoid known allergens and be educated about their condition. Intranasal corticosteroids are the most effective treatment and should be first-line therapy for mild to moderate disease. Moderate to severe disease not responsive to intranasal corticosteroids should be treated with second-line therapies, including antihistamines, decongestants, cromolyn, leukotriene receptor antagonists, and nonpharmacologic therapies (e.g., nasal irrigation). With the exception of cetirizine, second-generation antihistamines are less likely to cause sedation and impair performance. Immunotherapy should be considered in patients with a less than adequate response to usual treatments. Evidence does not support the use of mite-proof impermeable covers, air filtration systems, or delayed exposure to solid foods in infancy.
1. There is no specific treatment for House Dust Allergy, but depending to the symptoms. Medication includes bronchodilators, anti-allergics, antihistamines, NSAIDs, etc.
2. Allergic shot
Allergy shot, also known as immunotherapy, contains extracts from the most common substance which people are allergic to, including such as vacuuming, sweeping, and dusting, etc., by providing long-term relief from certain symptoms. In some people, after series of allergic shot, the disease is cured.
3. Etc.
G.5.2. Herbs
1. Garlic
It is best known for treating cold and flu and enhances immune system against alll types of foreign invasion. According to the study of "Immunomodulatory Effects of Aged Garlic Extract"
Eikai Kyo, Naoto Uda, Shigeo Kasuga and Yoichi Itakur, Posted in the "Journal of Nutrition" in March 2001, researchers strongly suggest that AGE (Aged Garlic Extract) could be a promising candidate as an immune modifier, which maintains the homeostasis of immune functions; further studies are warranted to determine when it is most beneficial.
2. Grape seed extract
Grape seed extract is best known for its antioxidant property in delay aging, it also acts as a natural histamine inhibitor, thus reducing the risk of allergic responses.
3. Licorice root
Beside is nest known to lower stomach acid levels, relieve heartburn and indigestion, licorice root is also boost the levels of interferon of immune system to fight off attacking viruses. According to the article of "Licorice, plantain and nettle herbs used in the treatment of Allergies" posted in Bitteroot restoration the author wrote that This ( Licorice root) can actually help to counteract many of the symptoms that are associated with allergies.: It also contains substances which work to thin the mucus and soothe to respiratory passages, which can reduce irritation that often accompanies allergies and their symptoms.
4. Turmeric
Turmeric paste has been used in traditional herbal medicine as an antimicrobial and anti-inflammatory agent, it also helps to treat allergy. According to an article "Vitamin D and turmeric for allergies" by Joe Graedon and Teresa Graedon posted in Washington Post, May 11-2009, the authors wrote that In animal studies, turmeric prevents the release of histamine from mast cells (Molecular Nutrition and Food Research, September 2008). If it works similarly in humans, this would prevent allergy symptoms from developing.
5. Sting Netttle
Sting Netttle contains antihistaminics which has been used as cream in treating symptoms of allergy. In a study of "Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis." by Roschek B Jr, Fink RC, McMichael M, Alberte RS.(HerbalScience Group LLC, 1004 Collier Center Way, Suite 200, Naples, FL 34110, USA.) posted in US National Library of Medicine National Institutes of Health, researchers found that Through the use of DART TOF-MS, which yields exact masses and relative abundances of compounds present in complex mixtures, bioactives have been identified in nettle that contribute to the inhibition of pro-inflammatory pathways related to allergic rhinitis. These results provide for the first time, a mechanistic understanding of the role of nettle extracts in reducing allergic and other inflammatory responses in vitro.
6. Etc.
G.5.3. Traditional Chinese medicine
In a study of "Complementary and alternative medicine in pediatric allergic disorders." by Li XM. (Source from Department of Pediatrics, Mount Sinai School of Medicine, New York, NY, USA., posted in PubMed, researcher indicated that in the last 2-3 years, there have been more controlled studies of TCM for allergic asthma and allergic rhinitis. Several publications including ours indicate that some TCM herbal formulas are well tolerated and produce some level of efficacy. Some herbal formulas also showed beneficial immunomodualtory effects. Several preclinical studies demonstrated that the food allergy herbal formula-2 was effective in protecting against peanut anaphylaxis in animal models. Two TCM products have entered clinical trials in the United States for treating asthma and food allergy, respectively. Both of these trials include children. In Summary, researcher concluded that Recent studies indicate that TCM therapy including herbal medicines and acupuncture for allergic disorders in children is well tolerated. There are also promising clinical and objective improvements. More controlled clinical studies are encouraged.
1. Xin Yi Hua is a lily-shaped flower with a hairy bud and Xin-yi-san (Magnolia Flower Powder)a. It is a type of traditional Chinese medicine used to treat allergy and dramatically reduces the symptoms of sneezing, anosmia, nasal congestion and profuse rhinorrhea (runny nose) caused by allergies triggered by dust mites, pets and fungi.According to the study of "Traditional Chinese medicine, Xin-yi-san, reduces nasal symptoms of patients with perennial allergic rhinitis by its diverse immunomodulatory effects" bySien-Hung Yang, Chia-Li Yu, Ying-Lin Chen, Sheng-Lin Chiao, Mei-Ling Chen f. Posted in International Immunopharmacology 10 (2010) 951–958, researchers found that this proposal is based on the fact that different combinations of Chinese herbs involve different mechanisms. It appears that the immunosuppressive and anti-inflammatory effects derived from the mixed formula of Chinese herbs are broader than XYS. Nevertheless,we found that XYS alone sufficiently exerts immunomodulatory effects on patients with AR.In conclusion, this study provides evidence to support that XYS, when used singly, is beneficial in nasal allergic inflammation through enhancing IL-10 and IL-8 production.
b. Ingredient
Main use: Expels wind-cold, unblocks nasal passages, congestion, loss of smell, sinus headache.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Cure Allergies Completely Naturally
Allergy Free For Life All Natural Cure
For Stopping Your Allergies In 5 Days
Causes
Allergy is defined as the type I reactions or Immediate Hypersensitivity as a result ofover production of Immunoglobulin E (IgE), a class of allergic antibody by the immune system against harmless substance that lead to mediated release of histamine and other mediators from mast cells and basophils, resulting in allergic reaction, including mucus secretion, sneezing, itching, etc.
G. House dust Allergy is defined as a condition of fabnormal immune reaction as a result of dust exposure related to common household chores such as vacuuming, sweeping, and dusting.
G.1. A. 1. How to determine the severity of the allergic effects
Depending to the allergy stimulating effect, some researchers suggested to scale the severity from 1 to 4 and followed by degeneration scale, but from -1 to -4
G.1.1. The severity scale from +1 to +4
+1. The first level of stimulation
If there is no symptoms at all or If the patient is alert and function morally after allergic efects.
+2. The second level of stimulation
The patient have become irritable, hyperactive, tense, thirsty, etc. after a suspected allergic effects
+3. The third level of stimulation
The patient have become hypomanic, aggressive, apprehensive, etc.
+4. The fourth level of stimulation
The patient have become mania, agitation, over excitement, etc.
G.1.2. Degeneration scale from -1 to -4
-1. If a patient is experience symptoms of reaction of runny nose, hive, diarrhea, etc.
-2. If a patient is experience symptoms of reaction of tiredness, fatigue, swelling etc.
-3. If a patient is experience symptoms of reaction of depression, mental disturbance, confusion, mood change, etc.
-4. If a patient is experience symptoms of reaction of sever depression, paranoia, etc.
G.2. Symptoms
Symptoms of house dust allergy are the result of airway inflammation of which can affects the daily activity including quality of life, productivity, and other chronic conditions, including asthma.
In the study of "Characteristics of Young Atopic Adults with Self-Reported Past Wheeze and Airway Hyperresponsiveness" by Yoshikawa T, Kanazawa H. (Source from Department of Sports Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan) posted in PubMed, researchers raised that the possibility that self-reported past-wheezers with AHR might form a distinct subgroup with features similar to past-asthmatics, which is one of the risk groups for adult asthma.
and
1. Asthma-like symptoms
2. Itching
3. Sneezing
4. Wheezing
5. Sinus pain
6. Tearing eyes
7. Runny nose
8. Itchy eyes and throat
9. Etc.
G.3. Diagnosis
If you are experience Allergic Rhinitis, it is possible to find what types of allergen have trigger that. After recording the family history and a complete physical exam. you doctor may order
1. Skin test
a. Intradermal test
It is one of most common test but time consuming( some patient may return for more 20 time for the injection) in diagnosis of allergy and depending to the symptoms, by injecting small amounts of diluted allergens into the top layers of the skin to see how the immune system react to them.
b. Skin prick testing
Similar to the Intradermal test, but the diagnosis involves in applying a drop of allergen into to punctures made on the skin.
2. Blood test (RadioAllergoSorbent Test)
This is the test for evaluating of the levels of IgE-mediated food allergies react to a particular allergen. If you RAST score is higher than the predictive value for that food, 95% chance you will have an allergic reaction. Unfortunately, non-IgE mediated allergies cannot be detected by this method.
3. Challenge Tests
Because of the risk of anaphylaxis, most doctors will avoid the test unless it is absolutely necessary and the test is performed only in the hospital. In this test, suspected allergen package into capsule taken by patient and signs or symptoms of an allergic reaction are observed.
4. Etc.
G..4. Prevention
There is no way to prevent them unless you can prevent yourdelf from dust exposure related to common household chores such as vacuuming, sweeping, and dusting. But one can always enhance the immune system by eating healthy and living a healthy lifestyle. For more information of healthy foods, visit 100+ Healthy Foods Classification
Since Allergies are caused by immune over reaction of certain harmless substance, enhancing immue system is one of the best way to prevent and treat them as some researchers suggested that allergies may be caused by weakened immune system over aggression. Vitamin A, E, C are antioxidants and free radical scavengers, they protect the immune system from free radicals attack and help to reduce levels of histamine in the blood. For more information of antioxidants and health effects
G.5. Treatments
G.5.1. Conventional medicine
According to the "Treatment of allergic rhinitis." American Family Physician - Volume 81, Issue 12 (June 2010), posted in MD preview, the writer wrote that allergic rhinitis is a common chronic respiratory illness that affects quality of life, productivity, and other comorbid conditions, including asthma. Treatment should be based on the patient's age and severity of symptoms. Patients should be advised to avoid known allergens and be educated about their condition. Intranasal corticosteroids are the most effective treatment and should be first-line therapy for mild to moderate disease. Moderate to severe disease not responsive to intranasal corticosteroids should be treated with second-line therapies, including antihistamines, decongestants, cromolyn, leukotriene receptor antagonists, and nonpharmacologic therapies (e.g., nasal irrigation). With the exception of cetirizine, second-generation antihistamines are less likely to cause sedation and impair performance. Immunotherapy should be considered in patients with a less than adequate response to usual treatments. Evidence does not support the use of mite-proof impermeable covers, air filtration systems, or delayed exposure to solid foods in infancy.
1. There is no specific treatment for House Dust Allergy, but depending to the symptoms. Medication includes bronchodilators, anti-allergics, antihistamines, NSAIDs, etc.
2. Allergic shot
Allergy shot, also known as immunotherapy, contains extracts from the most common substance which people are allergic to, including such as vacuuming, sweeping, and dusting, etc., by providing long-term relief from certain symptoms. In some people, after series of allergic shot, the disease is cured.
3. Etc.
G.5.2. Herbs
1. Garlic
It is best known for treating cold and flu and enhances immune system against alll types of foreign invasion. According to the study of "Immunomodulatory Effects of Aged Garlic Extract"
Eikai Kyo, Naoto Uda, Shigeo Kasuga and Yoichi Itakur, Posted in the "Journal of Nutrition" in March 2001, researchers strongly suggest that AGE (Aged Garlic Extract) could be a promising candidate as an immune modifier, which maintains the homeostasis of immune functions; further studies are warranted to determine when it is most beneficial.
2. Grape seed extract
Grape seed extract is best known for its antioxidant property in delay aging, it also acts as a natural histamine inhibitor, thus reducing the risk of allergic responses.
3. Licorice root
Beside is nest known to lower stomach acid levels, relieve heartburn and indigestion, licorice root is also boost the levels of interferon of immune system to fight off attacking viruses. According to the article of "Licorice, plantain and nettle herbs used in the treatment of Allergies" posted in Bitteroot restoration the author wrote that This ( Licorice root) can actually help to counteract many of the symptoms that are associated with allergies.: It also contains substances which work to thin the mucus and soothe to respiratory passages, which can reduce irritation that often accompanies allergies and their symptoms.
4. Turmeric
Turmeric paste has been used in traditional herbal medicine as an antimicrobial and anti-inflammatory agent, it also helps to treat allergy. According to an article "Vitamin D and turmeric for allergies" by Joe Graedon and Teresa Graedon posted in Washington Post, May 11-2009, the authors wrote that In animal studies, turmeric prevents the release of histamine from mast cells (Molecular Nutrition and Food Research, September 2008). If it works similarly in humans, this would prevent allergy symptoms from developing.
5. Sting Netttle
Sting Netttle contains antihistaminics which has been used as cream in treating symptoms of allergy. In a study of "Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis." by Roschek B Jr, Fink RC, McMichael M, Alberte RS.(HerbalScience Group LLC, 1004 Collier Center Way, Suite 200, Naples, FL 34110, USA.) posted in US National Library of Medicine National Institutes of Health, researchers found that Through the use of DART TOF-MS, which yields exact masses and relative abundances of compounds present in complex mixtures, bioactives have been identified in nettle that contribute to the inhibition of pro-inflammatory pathways related to allergic rhinitis. These results provide for the first time, a mechanistic understanding of the role of nettle extracts in reducing allergic and other inflammatory responses in vitro.
6. Etc.
G.5.3. Traditional Chinese medicine
In a study of "Complementary and alternative medicine in pediatric allergic disorders." by Li XM. (Source from Department of Pediatrics, Mount Sinai School of Medicine, New York, NY, USA., posted in PubMed, researcher indicated that in the last 2-3 years, there have been more controlled studies of TCM for allergic asthma and allergic rhinitis. Several publications including ours indicate that some TCM herbal formulas are well tolerated and produce some level of efficacy. Some herbal formulas also showed beneficial immunomodualtory effects. Several preclinical studies demonstrated that the food allergy herbal formula-2 was effective in protecting against peanut anaphylaxis in animal models. Two TCM products have entered clinical trials in the United States for treating asthma and food allergy, respectively. Both of these trials include children. In Summary, researcher concluded that Recent studies indicate that TCM therapy including herbal medicines and acupuncture for allergic disorders in children is well tolerated. There are also promising clinical and objective improvements. More controlled clinical studies are encouraged.
1. Xin Yi Hua is a lily-shaped flower with a hairy bud and Xin-yi-san (Magnolia Flower Powder)a. It is a type of traditional Chinese medicine used to treat allergy and dramatically reduces the symptoms of sneezing, anosmia, nasal congestion and profuse rhinorrhea (runny nose) caused by allergies triggered by dust mites, pets and fungi.According to the study of "Traditional Chinese medicine, Xin-yi-san, reduces nasal symptoms of patients with perennial allergic rhinitis by its diverse immunomodulatory effects" bySien-Hung Yang, Chia-Li Yu, Ying-Lin Chen, Sheng-Lin Chiao, Mei-Ling Chen f. Posted in International Immunopharmacology 10 (2010) 951–958, researchers found that this proposal is based on the fact that different combinations of Chinese herbs involve different mechanisms. It appears that the immunosuppressive and anti-inflammatory effects derived from the mixed formula of Chinese herbs are broader than XYS. Nevertheless,we found that XYS alone sufficiently exerts immunomodulatory effects on patients with AR.In conclusion, this study provides evidence to support that XYS, when used singly, is beneficial in nasal allergic inflammation through enhancing IL-10 and IL-8 production.
b. Ingredient
Main use: Expels wind-cold, unblocks nasal passages, congestion, loss of smell, sinus headache.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Chinese Herbs – Quan Shen (Rhizoma Bistortae)
Quan Shen is also known as Meadow bistort. The
bitter, tart and slightly cold herb has been used in TCM to treat
enteritis, dysentery, hepatitis.hemorrhoid, appendicitis, tonsillitis,
tracheitis, convulsion, edema, urination difficulty, etc., as it clears
Heat, expels toxin, disperses Dampness, resolves abscesses, etc., by
enhancing the functions of liver, lung and large intestine channels.
Ingredients
1. Tannin
2. Starch
3. Gallic acid
4. Succinic acid
5. 3,4-dihydroxybenzoic acid
6. D-catechol
7. L-epicatecho
8. 6-galloylglucose
9. 3,6-digalloylglucose
10. 2,6-dihydroxybenzoic acid
11. (-)-epicatechin-5-O-β-D-glucopyranoside
12. Etc.
Health Benefits
1. Antiradical activity
in the study of Antiradical potential of extracts measured with DPPH radical (2,2-diphenyl-1-picrylhydrazyl) and was expressed as the number of units per mg of extracts (TAU(515/mg)) and per g of raw material (TAU(515/g)). The amount of phenolic compounds was determined colorimetrically using Folin-Ciocalteu phenol reagent (3H₂O • P₂O5 • 13WO₃ • 5MoO₃ • 10H₂O), found that he strongest antiradical activity was noted for extracts obtained from Cinnamomi cortex; the number of antiradical units per mg of extract (TAU(515/mg)) was 10.31±1.052. The lowest antiradical features were exhibited by extract from Zingiberis rhizoma (0.28±0.174) and extract from Cichorii radix (0.38±0.669). The highest amount of phenolic compounds was measured for extracts from Bistortae rhizoma, with a value (in percentage) of 78.6±13.5(1).
2. Antitumor
In this study to evaluate thje chemopreventive efficacy of Antitumor B, a Chinese herbal mixture of six plants (Sophora tonkinensis, Polygonum bistorta, Prunella vulgaris, Sonchus arvensis L., Dictamnus dasycarpus, and Dioscorea bulbifera) on the development of 4-nitroquinoline-1-oxide (4NQO) induced oral squamous cell carcinomas in A/J mice, found thatsignificant amounts of obacunone, matrine, and maackiain in the blood after 1-wk treatment. The concentrations of these three compounds did not increase further at 18 wk, suggesting that plasma concentrations had reached a steady-state level at 1 wk. There was no significant body weight loss and there was no other obvious sign of toxicity in Antitumor B-treated mice. These results suggest that Antitumor B is a promising agent for human oral cancer chemoprevention(2).
3. Anti-inflammatory activity
In the study to investigate The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae for their anti-inflammatory activity, showed that administered (100 and 200 mg kg-1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve(3).
4. Etc.
Side Effects
1. Do not use the herb in case if not high heat and fire
symptoms
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22470189
(2) http://www.ncbi.nlm.nih.gov/pubmed/22086836
(3) http://www.ncbi.nlm.nih.gov/pubmed/8051612
Ingredients
1. Tannin
2. Starch
3. Gallic acid
4. Succinic acid
5. 3,4-dihydroxybenzoic acid
6. D-catechol
7. L-epicatecho
8. 6-galloylglucose
9. 3,6-digalloylglucose
10. 2,6-dihydroxybenzoic acid
11. (-)-epicatechin-5-O-β-D-glucopyranoside
12. Etc.
Health Benefits
1. Antiradical activity
in the study of Antiradical potential of extracts measured with DPPH radical (2,2-diphenyl-1-picrylhydrazyl) and was expressed as the number of units per mg of extracts (TAU(515/mg)) and per g of raw material (TAU(515/g)). The amount of phenolic compounds was determined colorimetrically using Folin-Ciocalteu phenol reagent (3H₂O • P₂O5 • 13WO₃ • 5MoO₃ • 10H₂O), found that he strongest antiradical activity was noted for extracts obtained from Cinnamomi cortex; the number of antiradical units per mg of extract (TAU(515/mg)) was 10.31±1.052. The lowest antiradical features were exhibited by extract from Zingiberis rhizoma (0.28±0.174) and extract from Cichorii radix (0.38±0.669). The highest amount of phenolic compounds was measured for extracts from Bistortae rhizoma, with a value (in percentage) of 78.6±13.5(1).
2. Antitumor
In this study to evaluate thje chemopreventive efficacy of Antitumor B, a Chinese herbal mixture of six plants (Sophora tonkinensis, Polygonum bistorta, Prunella vulgaris, Sonchus arvensis L., Dictamnus dasycarpus, and Dioscorea bulbifera) on the development of 4-nitroquinoline-1-oxide (4NQO) induced oral squamous cell carcinomas in A/J mice, found thatsignificant amounts of obacunone, matrine, and maackiain in the blood after 1-wk treatment. The concentrations of these three compounds did not increase further at 18 wk, suggesting that plasma concentrations had reached a steady-state level at 1 wk. There was no significant body weight loss and there was no other obvious sign of toxicity in Antitumor B-treated mice. These results suggest that Antitumor B is a promising agent for human oral cancer chemoprevention(2).
3. Anti-inflammatory activity
In the study to investigate The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum officinale L. Zygophyllaceae and Hamamelis virginiana L. Hamamelidaceae for their anti-inflammatory activity, showed that administered (100 and 200 mg kg-1, p.o.) before the induction of carrageenan rat paw oedema, extracts of P. bistorta significantly suppressed both the maximal oedema response and the total oedema response (monitored as area under the time course curve(3).
4. Etc.
Side Effects
1. Do not use the herb in case if not high heat and fire
symptoms
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22470189
(2) http://www.ncbi.nlm.nih.gov/pubmed/22086836
(3) http://www.ncbi.nlm.nih.gov/pubmed/8051612
Chinese Herbs – Quan Xie (Buthus martensi)
Quan Xie is also known as scorpion. The
neutral, acrid, sweet and toxic herb has been used in TCM to treat
epilepsy, stroke, paralysis, migraine, pain in arthritis, tetanus,
tuberculosis in lymph nodes, urticaria, , etc., as it calms Wind,
convulsions, relieve pain, expels toxins, disperses nodules, promotes
circulation in the collaterals, etc., by enhancing the liver channels.
Ingredients
1. Katsutoxin
2. Polypeptides
3. Tityustoxin
4. Hyaluronidase
5. Lecithin
6. Katsu acid
7. Trimethylamin
8. Betaine
9. Etc.
Health Benefits
1. Cardiovascular effects
Buthus martensii (Karsch) (BMK) scorpion envenomation is a common medical problem in China and BMK scorpion has been widely used in traditional Chinese medicine. In the study to investigate i.v. BMK venom injection significantly increased the blood pressure in conscious rats in a concentration-dependent manner (ED50 = 59 +/- 12 micrograms/kg), showed that BMK venom significantly increased the metabolism of InsP3 in dispersed cardiac myocytes, indicating a direct effect on cardiac myocytes. These results demonstrate the significant cardiovascular effects of BMK venom, which may be mediated by an alteration in InsP3 in cardiac myocytes but not by [Ca2+]i in vascular smooth muscle cells(1).
2. Antinociceptive activity
In the site-directed mutagenesis and mouse acetic acid writhing test used to investigate the role of Ser54 in the antinociceptive activity of BmK9 neurotoxin from the Buthus martensii Karsch scorpion, detailed mutagenesis analysis revealed that substitution of Ser54 by various polar amino acids produced no significant change in the antinociceptive activity, while all substitutions of nonpolar amino acid for Ser54 led to a significant loss of antinociceptive activity. Following the conformational analysis, it was suggested that Ser54 in BmK9 plays a functional role in the antinociceptive activity, the residue exerts its effect by means of a side-chain hydrogen bond(2).
3. Analgesic activity
In the study of an effective Escherichia coli expression system used to study the role of residues in the antitumor-analgesic peptide from Chinese scorpion Buthus martensii Karsch (BmKAGAP) and to evaluate the extent to which residues of the toxin core contribute to its analgesic activity, nine mutants of BmKAGAP obtained by PCR, showed that withthe ongoing efforts for establishing the structure and analgesic activity relationship of BmKAGAP, we have succeeded in pinpointing which residues are important for the analgesic activity(3).
4. Etc.
Side Effects
1. The herb can cause Allergic effects, including rash, urticaria with fever
2. Overdose can be toxic
3. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
4. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.htmlSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/8153958
(2) http://www.ncbi.nlm.nih.gov/pubmed/21906612
(3) http://www.ncbi.nlm.nih.gov/pubmed/20307602
Ingredients
1. Katsutoxin
2. Polypeptides
3. Tityustoxin
4. Hyaluronidase
5. Lecithin
6. Katsu acid
7. Trimethylamin
8. Betaine
9. Etc.
Health Benefits
1. Cardiovascular effects
Buthus martensii (Karsch) (BMK) scorpion envenomation is a common medical problem in China and BMK scorpion has been widely used in traditional Chinese medicine. In the study to investigate i.v. BMK venom injection significantly increased the blood pressure in conscious rats in a concentration-dependent manner (ED50 = 59 +/- 12 micrograms/kg), showed that BMK venom significantly increased the metabolism of InsP3 in dispersed cardiac myocytes, indicating a direct effect on cardiac myocytes. These results demonstrate the significant cardiovascular effects of BMK venom, which may be mediated by an alteration in InsP3 in cardiac myocytes but not by [Ca2+]i in vascular smooth muscle cells(1).
2. Antinociceptive activity
In the site-directed mutagenesis and mouse acetic acid writhing test used to investigate the role of Ser54 in the antinociceptive activity of BmK9 neurotoxin from the Buthus martensii Karsch scorpion, detailed mutagenesis analysis revealed that substitution of Ser54 by various polar amino acids produced no significant change in the antinociceptive activity, while all substitutions of nonpolar amino acid for Ser54 led to a significant loss of antinociceptive activity. Following the conformational analysis, it was suggested that Ser54 in BmK9 plays a functional role in the antinociceptive activity, the residue exerts its effect by means of a side-chain hydrogen bond(2).
3. Analgesic activity
In the study of an effective Escherichia coli expression system used to study the role of residues in the antitumor-analgesic peptide from Chinese scorpion Buthus martensii Karsch (BmKAGAP) and to evaluate the extent to which residues of the toxin core contribute to its analgesic activity, nine mutants of BmKAGAP obtained by PCR, showed that withthe ongoing efforts for establishing the structure and analgesic activity relationship of BmKAGAP, we have succeeded in pinpointing which residues are important for the analgesic activity(3).
4. Etc.
Side Effects
1. The herb can cause Allergic effects, including rash, urticaria with fever
2. Overdose can be toxic
3. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
4. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.htmlSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/8153958
(2) http://www.ncbi.nlm.nih.gov/pubmed/21906612
(3) http://www.ncbi.nlm.nih.gov/pubmed/20307602
Chinese Herbs – Ren Dong Teng (Caulis Lonicerae)
Ren Dong Teng is also known as Japanese
Honeysuckle Stem. The sweet and cold herb has been used in TCM as
Anti-inflammatory and Anti-spasm agent and to enhance the heart
function, lower blood cholesterol, etc. as it clears Heat, expels
toxins, disperses Wind-Heat-Damp, calms pain, etc. by enhancing the
functions of heart and lung channels.
Ingredients
1. Chlorogenic acid
2. Isochlorogenic acid
3. L:oganin
4. Secologanin dimethylacetal
5. Secologanin dimethylacetal
6. Vogeloside
7. Epi-vogeloside[2]
8. Hederagenin-3-O-α-L-rbinopyranoside
9. Hederagenin-3-O-β-D-glucopyranosyl(1→2)-α-L-arabinopyranoside
10. Hederagenin-3-O-α-L-arabinopyranosyl-28-O-β-D-glucopyranosyl(1→6)- β-D-glucopyranoside
11. Etc.
Health Benefits
1. Liver protective effects
In the study to investigate the Protective effects of 41 Taiwan crude drugs on rat hepatic injuries caused by carbon tetrachloride (CCl4) and alpha-naphthylisothiocyanate (ANIT)found that the methanol extracts of Elephantopi Herba and Lonicerae Flos inhibited the release of intrahepatic enzymes and histological changes by CCl4(1).
2. Phagocytosis
Twenty-six herbal preparations made from 24 medicinal herbs, categorized as antipyretics in Chinese materia medica, were tested in vitro to determine their effects upon phagocytosis of 32P-labelled Staphylococcus aureus by neutrophils isolated from bovine blood and milk, showed that when compared with PBSS (0.01 M phosphate buffered saline solution) controls, most of the herbs at high concentrations inhibited phagocytosis while at lower concentrations phagocytosis was increased. All 26 herbal preparations significantly increased blood neutrophil activity at their proper concentrations. The most active herbs in promoting blood neutrophil phagocytosis were observed for Herba verbenae, Flos chrysanthemi, Flos lonicerae, Radix sophorae flavescentis, Herba houttuyniae, Radix isatidis, Herba patriniae(2)
3. Inhibition of platelet activation
In the study to evaluate the effects of the polyphenolic compounds isolated from Lonicera japonica Thunb on platelet aggregation, platelet thromboxane biosynthesis and hydrogen peroxide-induced endothelial cell injury, showed that the inhibitory effect on platelet activation and the cytoprotective effect on hydrogen peroxide-induced cell injury may explain the possible role of polyphenolic compounds isolated from Lonicera japonica Thunb in maintaining vascular homeostasis(3).
4. Regulation of Proinflammatory Mediators
In teh study to investigate the anti-inflammatory mechanism of polyphenol components isolated from Korea L. japonica T. by nuclear factor-kappaB (NF-κB) and mitogen-activated protein kinases (MAPKs) pathway, indicated that that polyphenol components isolated from Korea L. japonica T. should have anti-inflammatory effect on LPS-stimulated RAW 264.7 cells through the decrease of proinflammatory mediators expression by suppressing NF-κB and p38 MAPK activity(4).
5. HepG2 Cells
In the study to investigate the anti-cancer and hepatic protective effect of Lonicera japonica Thunb. (L. japonica T.), found that Polyphenolic extract also decreased the expression of CDK1, CDC25C, cyclin B1, pro-caspases-3 and -9 and poly ADP ribose polymerase, and affected the levels of mitochondrial apoptotic-related proteins. The phosphorylation of extracellular signal-related kinase ½ (ERK 1/2), c-Jun N-terminal kinase (JNK), and p-38 mitogen-activated protein kinases (MAPKs) were increased in HepG2 cells treated with polyphenolic extract, whereas Akt was dephosphorylated. These results indicate that inhibition of PI3K/Akt and activation of MAPKs are pivotal in G2/M cell cycle arrest and apoptosis of human hepatocarcinoma cells mediated by polyphenolic extract(5).
6. Neuroprotective effects
in the investigation of the neuroprotective effects of Lonicera japonica THUNB. extract (LJ) on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in SH-SY5Y cells, showed that LJ has a potent anti-parkinsonism; this effect was mediated, at least in part, by inhibition of neurotoxicity, apoptotic cascade events, and oxidative stress via activation of MAPKs, PI3K/Akt, and NF-κB(6).
7. Etc.
Side Effects
1. Do not use in case of spleen deficiency
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.htmlSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/8301540
(2) http://www.ncbi.nlm.nih.gov/pubmed/1455927
(3) http://www.ncbi.nlm.nih.gov/pubmed/1603820
(4) http://www.ncbi.nlm.nih.gov/pubmed/22611435
(5) http://www.ncbi.nlm.nih.gov/pubmed/22561682
(6) http://www.ncbi.nlm.nih.gov/pubmed/22227216
Ingredients
1. Chlorogenic acid
2. Isochlorogenic acid
3. L:oganin
4. Secologanin dimethylacetal
5. Secologanin dimethylacetal
6. Vogeloside
7. Epi-vogeloside[2]
8. Hederagenin-3-O-α-L-rbinopyranoside
9. Hederagenin-3-O-β-D-glucopyranosyl(1→2)-α-L-arabinopyranoside
10. Hederagenin-3-O-α-L-arabinopyranosyl-28-O-β-D-glucopyranosyl(1→6)- β-D-glucopyranoside
11. Etc.
Health Benefits
1. Liver protective effects
In the study to investigate the Protective effects of 41 Taiwan crude drugs on rat hepatic injuries caused by carbon tetrachloride (CCl4) and alpha-naphthylisothiocyanate (ANIT)found that the methanol extracts of Elephantopi Herba and Lonicerae Flos inhibited the release of intrahepatic enzymes and histological changes by CCl4(1).
2. Phagocytosis
Twenty-six herbal preparations made from 24 medicinal herbs, categorized as antipyretics in Chinese materia medica, were tested in vitro to determine their effects upon phagocytosis of 32P-labelled Staphylococcus aureus by neutrophils isolated from bovine blood and milk, showed that when compared with PBSS (0.01 M phosphate buffered saline solution) controls, most of the herbs at high concentrations inhibited phagocytosis while at lower concentrations phagocytosis was increased. All 26 herbal preparations significantly increased blood neutrophil activity at their proper concentrations. The most active herbs in promoting blood neutrophil phagocytosis were observed for Herba verbenae, Flos chrysanthemi, Flos lonicerae, Radix sophorae flavescentis, Herba houttuyniae, Radix isatidis, Herba patriniae(2)
3. Inhibition of platelet activation
In the study to evaluate the effects of the polyphenolic compounds isolated from Lonicera japonica Thunb on platelet aggregation, platelet thromboxane biosynthesis and hydrogen peroxide-induced endothelial cell injury, showed that the inhibitory effect on platelet activation and the cytoprotective effect on hydrogen peroxide-induced cell injury may explain the possible role of polyphenolic compounds isolated from Lonicera japonica Thunb in maintaining vascular homeostasis(3).
4. Regulation of Proinflammatory Mediators
In teh study to investigate the anti-inflammatory mechanism of polyphenol components isolated from Korea L. japonica T. by nuclear factor-kappaB (NF-κB) and mitogen-activated protein kinases (MAPKs) pathway, indicated that that polyphenol components isolated from Korea L. japonica T. should have anti-inflammatory effect on LPS-stimulated RAW 264.7 cells through the decrease of proinflammatory mediators expression by suppressing NF-κB and p38 MAPK activity(4).
5. HepG2 Cells
In the study to investigate the anti-cancer and hepatic protective effect of Lonicera japonica Thunb. (L. japonica T.), found that Polyphenolic extract also decreased the expression of CDK1, CDC25C, cyclin B1, pro-caspases-3 and -9 and poly ADP ribose polymerase, and affected the levels of mitochondrial apoptotic-related proteins. The phosphorylation of extracellular signal-related kinase ½ (ERK 1/2), c-Jun N-terminal kinase (JNK), and p-38 mitogen-activated protein kinases (MAPKs) were increased in HepG2 cells treated with polyphenolic extract, whereas Akt was dephosphorylated. These results indicate that inhibition of PI3K/Akt and activation of MAPKs are pivotal in G2/M cell cycle arrest and apoptosis of human hepatocarcinoma cells mediated by polyphenolic extract(5).
6. Neuroprotective effects
in the investigation of the neuroprotective effects of Lonicera japonica THUNB. extract (LJ) on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in SH-SY5Y cells, showed that LJ has a potent anti-parkinsonism; this effect was mediated, at least in part, by inhibition of neurotoxicity, apoptotic cascade events, and oxidative stress via activation of MAPKs, PI3K/Akt, and NF-κB(6).
7. Etc.
Side Effects
1. Do not use in case of spleen deficiency
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.htmlSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/8301540
(2) http://www.ncbi.nlm.nih.gov/pubmed/1455927
(3) http://www.ncbi.nlm.nih.gov/pubmed/1603820
(4) http://www.ncbi.nlm.nih.gov/pubmed/22611435
(5) http://www.ncbi.nlm.nih.gov/pubmed/22561682
(6) http://www.ncbi.nlm.nih.gov/pubmed/22227216
Chinese Herbs – Ren Shen (Radix Ginseng)
Ren Shen is also known as Gingshen. The smells
aromatic, tastes sweet and slightly warm herbs had been used in TCM as
improved immune system, Anti Cancer, Anti aging, Anti stress, etc. agent
and to generates fluids and reduce thirst, for xinqixu (heart qi
deficient) palpitations with instant sweating and anxiety, insomnia,
dizziness/headache, forgetfulness, impotence, diabetes, bleeding in the
vagina not during period, seizures in children, chronic weakness, etc.
as it strongly tonifies Original Qi, tonifies the Spleen and the Lungs,
promotes generation of Body Fluids, calms thirs and the Mind, etc. by
enhancing the functions of spleen and lung channels.
Ingredients
1. Saponins
2. Panaxynol
3. Ginsenyne
4. Alpha pansinsene
5. Beta pansinsene
6. Beta farnesene
7. Bicyclogermacrene
8. Beta elemene
9. Gama elemene
10. Alpha neodovene
11. Beta neodovene
12. Alpha humulene
13. Beta humulene
14. Ccaryophyllene
15. Beta gurjunene
16. Alpha gurjunene
17. Alpha selinene
18. Beta selinene
19. Gama selinene
20. Selin-4, alpha guaiene
21. Gama cubebene
22. Beta patchoulene
23. Hepatadecanol-1
24. Etc.
Health Benefits
1. Erectile dysfunction
Panax ginseng has been used as yang promoting herb as it improves sexual desire, treat erectile dysfunction and impotent over thousands of year. In the investigation of the effectiveness of Korean ginseng and mountain ginseng (Panax ginseng CA Meyer) for treating erectile dysfunction, found that A total of 86 patients completed 8 weeks of treatment. The scores on the five domains of the IIEF after medication were significantly higher than the baseline scores in the group treated with TMGE (P<0.05), whereas no significant improvement was observed in the placebo group (P>0.05). Erectile function and overall satisfaction scores after medication were significantly higher in the TMGE group than in the placebo group (P<0.05). Erectile function of patients in the TMGE-treated group significantly improved, suggesting that TMGE could be utilized for improving erectile function in male patients, according to “Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction”by Kim TH, Jeon SH, Hahn EJ, Paek KY, Park JK, Youn NY, Lee HL.(1)
2. Antioxidant activity
In the evaluation of the extraction conditions of polysaccharides from the rhizomes of Panax japonicus C.A. Meyer and its antioxidant effect found that antioxidant activity exhibited Panax japonicus polysaccharides (PJP) had a good potential for antioxidant, according to “Optimization of polysaccharides from Panax japonicus C.A. Meyer by RSM and its anti-oxidant activity” by Wang R, Chen P, Jia F, Tang J, Ma F.(2)
3. Antipsychotic effect
In the investigation of Panax quinquefolium (PQ) and its significant neuroactive properties for its antipsychotic potential found that PQ blocked ketamine induced memory impairment in the passive avoidance paradigm. In the chronic studies, PQ reduced the ketamine induced enhanced immobility in the forced swim test and did not show extra-pyramidal side effects in bar test and wood block test of catalepsy. These behavioural effects were compared with standard drugs haloperidol and clozapine. Further PQ reduced DA and 5-HT content after chronic treatment, but not after acute administration, according to “Evaluation of the Antipsychotic Potential of Panax quinquefolium in Ketamine Induced Experimental Psychosis Model in Mice” by Chatterjee M, Singh S, Kumari R, Verma AK, Palit G.(3)
4. Anti-cancers
In the identification of Panax ginseng as a herb used in Asia for the prevention and treatment of various diseases, including cancer found that the results clearly indicate the structure-related activities in which the compound with less polar chemical structures possesses higher cytotoxic activity towards cancer cells, according to “The in vitro structure-related anti-cancer activity of ginsenosides and their derivatives” by Dong H, Bai LP, Wong VK, Zhou H, Wang JR, Liu Y, Jiang ZH, Liu L.(4)
5. Neuroprotective effect
In the analyzing Panax ginseng C.A. Meyer and its beneficial effects in cerebral ischemia and inhibition of the inflammatory cascade in sepsis found that Ginsenoside Rb1 (GRb1) partially inhibited the activation of nuclear factor-κB (NF-κB) pathway from 6 h to 72 h after ischemia and reperfusion onset, as determined by the expression of total and phosphorylated NF-κB/p65, inhibitor protein of κB (IκB)-α, and IκB-kinase complex (IKK)-α. All these results indicate that suppression of local inflammation after cerebral ischemia might be one mechanism that contributes to the neuroprotection of GRb1, according to “Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia” by Zhu J, Jiang Y, Wu L, Lu T, Xu G, Liu X.(5)
6. Immunological activities
In the study of Water-soluble ginseng oligosaccharides (designated as WGOS) with a degree of polymerization ranging from 2 to 10 were obtained from warm-water extract of Panax ginseng roots, found that WGOS were potent B and T-cell stimulators and WGOS-1 has the highest immunostimulating effect on lymphocyte proliferation among those purified fractions. It is hoped that the WGOS will be developed into functional food or medicine, according to “Structural characterization and immunological activities of the water-soluble oligosaccharides isolated from the Panax ginseng roots” by Wan D, Jiao L, Yang H, Liu S.(6)
7. Breast cancer
In the investigation the anticancer effects of warming and relieving cold phlegm formula (, WRCP), a mixture composed of the aqueous extracts of Aconitum carmichaeli, Rhizoma bolbostemmatis, Phytolacca acinosa, Panax notoginseng, and Gekko swinhonis G Å« enther, combined with 5-fluorouracil (5-FU) on human breast cancer found that the treatment combination of WRCP and 5-FU was more effective in the inhibition of tumor growth than either agent alone and may have potentially additional benefit in improving the general condition and immunity of the mice with human breast cancer cell implants, according to “Anticancer effects of 5-fluorouracil combined with warming and relieving cold phlegm formula on human breast cancer” by Wang XL, Ma F, Wu XZ(7)
8. Type 2 diabetes
In the researches of Red ginseng (RG, Panax ginseng C.A. Meyer) and its effect for treating type 2 diabetes mellitus (DM) found that the evidence for the effectiveness of RG in controlling glucose in type 2 DM is not convincing. Few included studies with various treatment regimens prohibit definitive conclusions. More rigorous studies are needed to clarify the effects of RG on this condition, according to “Red ginseng for type 2 diabetes mellitus: A systematic review of randomized controlled trials” by Kim S, Shin BC, Lee MS, Lee H, Ernst E.(8)
9. Metabolic cardiovascular disease
In the identification of several traditional Chinese medicine and teirs effect on metabolic cardiovascular disease, authors emphasized that the relationship among axis of excessive ROS/RNS-mitochondrial dysfunction-apoptosis-atherosclerosis. They also introduce several traditional Chinese medicines such as Ophiopogon japonicus, butin, Panax ginseng, Pueraria lobata, Solanum lyratum and so on in the treatment of relevant diseases through anti-ROS/RNS mechanism. Moreover, the TCMs also can anti-cancer and anti-fatigue,which show the speciality of TCMs different from the single effect of classical western medicines, according to “[Mitochondrial dysfunction induced by excessive ROS/RNS-metabolic cardiovascular disease and traditional Chinese medicines intervention].[Article in Chinese]” by Zhang C, Liu J, Pan H, Yang X, Bian K.(9)
10. Prostate hyperplasia
in the demonstration of Panax ginseng’s pharmacological activities on benign prostatic hyperplasia (BPH) found that 20(S)-Rg3 downregulated AR by facilitating the degradation of AR protein. WKRG and 20(S)-Rg3 were found to have new pharmacological activities against testosterone-induced prostate overgrowth. Given that red ginseng has been used safely in Asia for 1000 years, red ginseng and 20(S)-Rg3 could be potential therapeutic regimens for treating BPH, according to “Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling” by Bae JS, Park HS, Park JW, Li SH, Chun YS(10)
11. HL-60 cells
In the classification of Four new triterpene saponins, ginsenosides Rh (14)-Rh (17) ( 1- 4), along with two known compounds, 20( S)-ginsenoside Rg (2) and dammar-( E)-20(22),24-diene-3 β,6 α,12 β-triol, and theirs effect on HL-60 cells found that the isolated compounds were tested for IN VITRO cytotoxicity against HL-60 cells, according to “Four New Dammarane-Type Triterpene Saponins from the Stems and Leaves of Panax ginseng and Their Cytotoxicity on HL-60 Cells” by Li KK, Yao CM, Yang XW.(11)
12. Wound healing
In the investigation of herbal drugs (Panax ginseng, beta-sitosterol from Aloe vera, calycosin from Radix Astragali, and extracts from Hippophae rhamnoides L. and Angelica sinensis.) and theirs effect on wound healing indicated that the use of plants and their extracts as potential therapeutic agents with pro- or antiangiogenic activity. Since the anticancer and antiangiogenic properties of many phytomedicines have been amply reviewed elsewhere this paper will focus on the treatment of vascular insufficiency in wound healing, according to “Proangiogenic activity of plant extracts in accelerating wound healing – a new face of old phytomedicines” byMajewska I, Gendaszewska-Darmach E.(12)
13. Cardiovascular Disorders
In the evaluation of plethora of pharmacological properties of North American ginseng (Panax quinquefolius) and Asian ginseng (Panax ginseng) found that Experimental studies have revealed a number of beneficial properties of ginseng, particularly in the area of cardiac protection, where ginseng and ginsenosides have been shown to protect the ischaemic and reperfused heart in a variety of experimental models. Emerging evidence also suggests that ginseng attenuates myocardial hypertrophy, thus blunting the remodelling and heart failure processes. However, clinical evidence of efficacy is not convincing, likely owing primarily to the paucity of well designed, randomized, controlled clinical trials, according to “Therapeutic Potential of Ginseng in the Management of Cardiovascular Disorders” by Karmazyn M, Moey M, Gan XT.(13)
14. Atherosclerosis
In the association of the herbal remedies on the prevention and treatment of AS found that mixed herbal preparations with multiple active ingredients may be preferable for the prevention and treatment of AS. Further rigorously designed pharmacological evaluation and multi-centred clinical trials are warranted, according to “Herbal Remedies Supply a Novel Prospect for the Treatment of Atherosclerosis: A Review of Current Mechanism Studies” by Zeng Y, Song JX, Shen XC.(14)
Side Effects
1. Overdoses can cause toxicity such as headaches, insomnia, anxiety, elevated blood pressure, rapid respiration and Oral dosage of 200 ml of saponins may cause allergic reactions of rash, itchiness, dizziness, headache, rising of body temperature and bleeding
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/19234482
(2) http://www.ncbi.nlm.nih.gov/pubmed/22214823
(3) http://www.ncbi.nlm.nih.gov/pubmed/22189635
(4) http://www.ncbi.nlm.nih.gov/pubmed/22183886
(5) http://www.ncbi.nlm.nih.gov/pubmed/22173011
(6) http://www.ncbi.nlm.nih.gov/pubmed/22183124
(7) http://www.ncbi.nlm.nih.gov/pubmed/22160948
(8) http://www.ncbi.nlm.nih.gov/pubmed/22139546
(9) http://www.ncbi.nlm.nih.gov/pubmed/22121816
(10) http://www.ncbi.nlm.nih.gov/pubmed/22101440
(11) http://www.ncbi.nlm.nih.gov/pubmed/22034065
(12) http://www.ncbi.nlm.nih.gov/pubmed/22030557
(13) http://www.ncbi.nlm.nih.gov/pubmed/21975571
(14) http://www.ncbi.nlm.nih.gov/pubmed/21928391
Ingredients
1. Saponins
2. Panaxynol
3. Ginsenyne
4. Alpha pansinsene
5. Beta pansinsene
6. Beta farnesene
7. Bicyclogermacrene
8. Beta elemene
9. Gama elemene
10. Alpha neodovene
11. Beta neodovene
12. Alpha humulene
13. Beta humulene
14. Ccaryophyllene
15. Beta gurjunene
16. Alpha gurjunene
17. Alpha selinene
18. Beta selinene
19. Gama selinene
20. Selin-4, alpha guaiene
21. Gama cubebene
22. Beta patchoulene
23. Hepatadecanol-1
24. Etc.
Health Benefits
1. Erectile dysfunction
Panax ginseng has been used as yang promoting herb as it improves sexual desire, treat erectile dysfunction and impotent over thousands of year. In the investigation of the effectiveness of Korean ginseng and mountain ginseng (Panax ginseng CA Meyer) for treating erectile dysfunction, found that A total of 86 patients completed 8 weeks of treatment. The scores on the five domains of the IIEF after medication were significantly higher than the baseline scores in the group treated with TMGE (P<0.05), whereas no significant improvement was observed in the placebo group (P>0.05). Erectile function and overall satisfaction scores after medication were significantly higher in the TMGE group than in the placebo group (P<0.05). Erectile function of patients in the TMGE-treated group significantly improved, suggesting that TMGE could be utilized for improving erectile function in male patients, according to “Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction”by Kim TH, Jeon SH, Hahn EJ, Paek KY, Park JK, Youn NY, Lee HL.(1)
2. Antioxidant activity
In the evaluation of the extraction conditions of polysaccharides from the rhizomes of Panax japonicus C.A. Meyer and its antioxidant effect found that antioxidant activity exhibited Panax japonicus polysaccharides (PJP) had a good potential for antioxidant, according to “Optimization of polysaccharides from Panax japonicus C.A. Meyer by RSM and its anti-oxidant activity” by Wang R, Chen P, Jia F, Tang J, Ma F.(2)
3. Antipsychotic effect
In the investigation of Panax quinquefolium (PQ) and its significant neuroactive properties for its antipsychotic potential found that PQ blocked ketamine induced memory impairment in the passive avoidance paradigm. In the chronic studies, PQ reduced the ketamine induced enhanced immobility in the forced swim test and did not show extra-pyramidal side effects in bar test and wood block test of catalepsy. These behavioural effects were compared with standard drugs haloperidol and clozapine. Further PQ reduced DA and 5-HT content after chronic treatment, but not after acute administration, according to “Evaluation of the Antipsychotic Potential of Panax quinquefolium in Ketamine Induced Experimental Psychosis Model in Mice” by Chatterjee M, Singh S, Kumari R, Verma AK, Palit G.(3)
4. Anti-cancers
In the identification of Panax ginseng as a herb used in Asia for the prevention and treatment of various diseases, including cancer found that the results clearly indicate the structure-related activities in which the compound with less polar chemical structures possesses higher cytotoxic activity towards cancer cells, according to “The in vitro structure-related anti-cancer activity of ginsenosides and their derivatives” by Dong H, Bai LP, Wong VK, Zhou H, Wang JR, Liu Y, Jiang ZH, Liu L.(4)
5. Neuroprotective effect
In the analyzing Panax ginseng C.A. Meyer and its beneficial effects in cerebral ischemia and inhibition of the inflammatory cascade in sepsis found that Ginsenoside Rb1 (GRb1) partially inhibited the activation of nuclear factor-κB (NF-κB) pathway from 6 h to 72 h after ischemia and reperfusion onset, as determined by the expression of total and phosphorylated NF-κB/p65, inhibitor protein of κB (IκB)-α, and IκB-kinase complex (IKK)-α. All these results indicate that suppression of local inflammation after cerebral ischemia might be one mechanism that contributes to the neuroprotection of GRb1, according to “Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia” by Zhu J, Jiang Y, Wu L, Lu T, Xu G, Liu X.(5)
6. Immunological activities
In the study of Water-soluble ginseng oligosaccharides (designated as WGOS) with a degree of polymerization ranging from 2 to 10 were obtained from warm-water extract of Panax ginseng roots, found that WGOS were potent B and T-cell stimulators and WGOS-1 has the highest immunostimulating effect on lymphocyte proliferation among those purified fractions. It is hoped that the WGOS will be developed into functional food or medicine, according to “Structural characterization and immunological activities of the water-soluble oligosaccharides isolated from the Panax ginseng roots” by Wan D, Jiao L, Yang H, Liu S.(6)
7. Breast cancer
In the investigation the anticancer effects of warming and relieving cold phlegm formula (, WRCP), a mixture composed of the aqueous extracts of Aconitum carmichaeli, Rhizoma bolbostemmatis, Phytolacca acinosa, Panax notoginseng, and Gekko swinhonis G Å« enther, combined with 5-fluorouracil (5-FU) on human breast cancer found that the treatment combination of WRCP and 5-FU was more effective in the inhibition of tumor growth than either agent alone and may have potentially additional benefit in improving the general condition and immunity of the mice with human breast cancer cell implants, according to “Anticancer effects of 5-fluorouracil combined with warming and relieving cold phlegm formula on human breast cancer” by Wang XL, Ma F, Wu XZ(7)
8. Type 2 diabetes
In the researches of Red ginseng (RG, Panax ginseng C.A. Meyer) and its effect for treating type 2 diabetes mellitus (DM) found that the evidence for the effectiveness of RG in controlling glucose in type 2 DM is not convincing. Few included studies with various treatment regimens prohibit definitive conclusions. More rigorous studies are needed to clarify the effects of RG on this condition, according to “Red ginseng for type 2 diabetes mellitus: A systematic review of randomized controlled trials” by Kim S, Shin BC, Lee MS, Lee H, Ernst E.(8)
9. Metabolic cardiovascular disease
In the identification of several traditional Chinese medicine and teirs effect on metabolic cardiovascular disease, authors emphasized that the relationship among axis of excessive ROS/RNS-mitochondrial dysfunction-apoptosis-atherosclerosis. They also introduce several traditional Chinese medicines such as Ophiopogon japonicus, butin, Panax ginseng, Pueraria lobata, Solanum lyratum and so on in the treatment of relevant diseases through anti-ROS/RNS mechanism. Moreover, the TCMs also can anti-cancer and anti-fatigue,which show the speciality of TCMs different from the single effect of classical western medicines, according to “[Mitochondrial dysfunction induced by excessive ROS/RNS-metabolic cardiovascular disease and traditional Chinese medicines intervention].[Article in Chinese]” by Zhang C, Liu J, Pan H, Yang X, Bian K.(9)
10. Prostate hyperplasia
in the demonstration of Panax ginseng’s pharmacological activities on benign prostatic hyperplasia (BPH) found that 20(S)-Rg3 downregulated AR by facilitating the degradation of AR protein. WKRG and 20(S)-Rg3 were found to have new pharmacological activities against testosterone-induced prostate overgrowth. Given that red ginseng has been used safely in Asia for 1000 years, red ginseng and 20(S)-Rg3 could be potential therapeutic regimens for treating BPH, according to “Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling” by Bae JS, Park HS, Park JW, Li SH, Chun YS(10)
11. HL-60 cells
In the classification of Four new triterpene saponins, ginsenosides Rh (14)-Rh (17) ( 1- 4), along with two known compounds, 20( S)-ginsenoside Rg (2) and dammar-( E)-20(22),24-diene-3 β,6 α,12 β-triol, and theirs effect on HL-60 cells found that the isolated compounds were tested for IN VITRO cytotoxicity against HL-60 cells, according to “Four New Dammarane-Type Triterpene Saponins from the Stems and Leaves of Panax ginseng and Their Cytotoxicity on HL-60 Cells” by Li KK, Yao CM, Yang XW.(11)
12. Wound healing
In the investigation of herbal drugs (Panax ginseng, beta-sitosterol from Aloe vera, calycosin from Radix Astragali, and extracts from Hippophae rhamnoides L. and Angelica sinensis.) and theirs effect on wound healing indicated that the use of plants and their extracts as potential therapeutic agents with pro- or antiangiogenic activity. Since the anticancer and antiangiogenic properties of many phytomedicines have been amply reviewed elsewhere this paper will focus on the treatment of vascular insufficiency in wound healing, according to “Proangiogenic activity of plant extracts in accelerating wound healing – a new face of old phytomedicines” byMajewska I, Gendaszewska-Darmach E.(12)
13. Cardiovascular Disorders
In the evaluation of plethora of pharmacological properties of North American ginseng (Panax quinquefolius) and Asian ginseng (Panax ginseng) found that Experimental studies have revealed a number of beneficial properties of ginseng, particularly in the area of cardiac protection, where ginseng and ginsenosides have been shown to protect the ischaemic and reperfused heart in a variety of experimental models. Emerging evidence also suggests that ginseng attenuates myocardial hypertrophy, thus blunting the remodelling and heart failure processes. However, clinical evidence of efficacy is not convincing, likely owing primarily to the paucity of well designed, randomized, controlled clinical trials, according to “Therapeutic Potential of Ginseng in the Management of Cardiovascular Disorders” by Karmazyn M, Moey M, Gan XT.(13)
14. Atherosclerosis
In the association of the herbal remedies on the prevention and treatment of AS found that mixed herbal preparations with multiple active ingredients may be preferable for the prevention and treatment of AS. Further rigorously designed pharmacological evaluation and multi-centred clinical trials are warranted, according to “Herbal Remedies Supply a Novel Prospect for the Treatment of Atherosclerosis: A Review of Current Mechanism Studies” by Zeng Y, Song JX, Shen XC.(14)
Side Effects
1. Overdoses can cause toxicity such as headaches, insomnia, anxiety, elevated blood pressure, rapid respiration and Oral dosage of 200 ml of saponins may cause allergic reactions of rash, itchiness, dizziness, headache, rising of body temperature and bleeding
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
Chinese Secrets To Fatty Liver And Obesity Reversal
Use The Revolutionary Findings To Achieve
Optimal Health And Loose Weight
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Popular Chinese Herbs http://kylejnorton.blogspot.ca/p/chinese-herbs.html
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/19234482
(2) http://www.ncbi.nlm.nih.gov/pubmed/22214823
(3) http://www.ncbi.nlm.nih.gov/pubmed/22189635
(4) http://www.ncbi.nlm.nih.gov/pubmed/22183886
(5) http://www.ncbi.nlm.nih.gov/pubmed/22173011
(6) http://www.ncbi.nlm.nih.gov/pubmed/22183124
(7) http://www.ncbi.nlm.nih.gov/pubmed/22160948
(8) http://www.ncbi.nlm.nih.gov/pubmed/22139546
(9) http://www.ncbi.nlm.nih.gov/pubmed/22121816
(10) http://www.ncbi.nlm.nih.gov/pubmed/22101440
(11) http://www.ncbi.nlm.nih.gov/pubmed/22034065
(12) http://www.ncbi.nlm.nih.gov/pubmed/22030557
(13) http://www.ncbi.nlm.nih.gov/pubmed/21975571
(14) http://www.ncbi.nlm.nih.gov/pubmed/21928391
Subscribe to:
Posts (Atom)