Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia - The Free Radical scavengers - Vitamin A

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                               The Antioxidants

Free radicals are atoms, molecules, or ions with unpaired electrons through chemical bonds with other atoms or molecules during a chemical reaction. They may have positive, negative or zero charge.

Free Radicals play an important role in the function of the Immune System. The immune system produces free radicals to kill foreign microbes(152)(153), but the production of free radical sometime can be excessive, leading to formation of a large number of free radicals(154)(155). The domino effects have shown to induce many chronic illness, such as cancers(155).
Furthermore, free radicals also displays over expression of oxidative stress, inducing varies form of chronic illness including metabolic syndrome(156).

                            The Free Radical scavengers

1. Vitamin A
vitamin A plays an essential roles in enhancing a broad range of immune processes, including white blood cells activation and proliferation(157)of T-helper-cell differentiation, the production of specific antibody in regulation of the immune response(158). According to the Suleyman Demirel University, Concentrations of vitamins A were significantly lower in patients with fibromyalgia than in controls, leading to over displayment of reactive oxygen species (ROS) in the etiology and pathogenesis of fibromyalgia(159).
Furthermore, in the evaluation of a total of 43 patients with FM and 44 healthy women, FM group
showed a mean consumption of nutrients lower than CT group, including vitamin A(160).
Deficiency of concentration may play an important role in exacerbate the over expression of Fibromyalgia but excess amount of vitamin A may also worsen the the symptoms of soft tissue rheumatism(161) Dr. Romano TJ. suggested.

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and restore your health naturally with Chinese diet

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References

(152 Free Radicals, Antioxidants in Disease and Health by Lien Ai Pham-Huy,1 Hua He,2 and Chuong Pham-Huy3(PMC)
(153) Superoxide Anion and Its Functions(Beta Forces)
(154) Free radicals and antioxidants in normal physiological functions and human disease by Valko M1, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J.(PubMed)
(155) Free radicals, metals and antioxidants in oxidative stress-induced cancer by Valko M1, Rhodes CJ, Moncol J, Izakovic M, Mazur M.(PubMed)

(156) Clinical implications of oxidative stress and potential role of natural antioxidants in diabetic vascular complications by Ceriello A1, Testa R2, Genovese S3.(PubMed)
(157) Cellular immunity in osteoarthritis: novel concepts for an old disease by Liossis SN1, Tsokos GC.(PubMed)
(158) Free Radicals, Antioxidants in Disease and Health by Lien Ai Pham-Huy,1 Hua He,2 and Chuong Pham-Huy3(PMC)

(159) Levels of lipid peroxidation, nitric oxide, and antioxidant vitamins in plasma of patients with fibromyalgia by Akkuş S1, Naziroğlu M, Eriş S, Yalman K, Yilmaz N, Yener M.(PubMed)

(160) Food intake assessment and quality of life in women with fibromyalgia.

[Article in English, Portuguese] by Batista ED1, Andretta A2, Miranda RC3, Nehring J4, Paiva ED2, Schieferdecker ME3.(PubMed)

(161) Exacerbation of soft tissue rheumatism by excess vitamin A: case reviews with clinical vignette by Romano TJ.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The Free Radical scavengers- Vitamin C

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

The Antioxidants

Free radicals are atoms, molecules, or ions with unpaired electrons through chemical bonds with other atoms or molecules during a chemical reaction. They may have positive, negative or zero charge.

Free Radicals play an important role in the function of the Immune System. The immune system produces free radicals to kill foreign microbes(152)(153), but the production of free radical sometime can be excessive, leading to formation of a large number of free radicals(154)(155). The domino effects have shown to induce many chronic illness, such as cancers(155).
Furthermore, free radicals also displays over expression of oxidative stress, inducing varies form of chronic illness including metabolic syndrome(156).

                            The Free Radical scavengers

2. Vitamin C
Vitamin C, also known as L-ascorbate, a water soluble vitamin with a chemical structure formula of C6H6O6  is best known for it's antioxidant property in strengthening the immune system.Due to recent promotion of western diet in some developed country, deficiencies of micronutrients are emerging as the limiting factors in ensuring children's optimal health, according Bayer Consumer Care Ltd(162). Deficiency of vitamin C and zinc in fact, interfere with normal children's growth and development(162). Researchers found that vitamin C raised the concentration in the blood of total immunoglobulin(163) in promotion of the ability of antibodies and phagocytic cells to clear pathogens(164).
Dr. Altindag O and Dr. Celik H. said, " patients with fibromyalgia are exposed to oxidative stress and this increased oxidative stress may play a role in the etiopathogenesis of the disease. Supplementation of antioxidant vitamins such as vitamins C and E to the therapy may be indicated"(165).

According to the University of Kuopio,  vegan diet rich in antioxidants, lactobacilli and fibre, have shown to benefit patient with rheumatoid disorder(166).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(162) Essential role of vitamin C and zinc in child immunity and health by Maggini S1, Wenzlaff S, Hornig D.(PubMed)
(163) New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate by Hae-Suk Kim,a Michael J. Quon,c and Jeong-a Kima,b(PMC)
(164) Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications by Singh BN1, Shankar S, Srivastava RK.(PubMed)

(165) Total antioxidant capacity and the severity of the pain in patients with fibromyalgia by Altindag O1, Celik H.(PubMed)

(166) Antioxidants in vegan diet and rheumatic disorders by Hänninen1, Kaartinen K, Rauma AL, Nenonen M, Törrönen R, Häkkinen AS, Adlercreutz H, Laakso J.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The Phytochemicals: Boswellic acid

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                       The Phytochemicals

Boswellic acid
Gum-resin extracts of Boswellia serrata have been traditionally used in folk medicine for centuries to treat various chronic inflammatory diseases. recent study showed that the acid are also responsible for inhibition of pro-inflammatory enzymes(143). Dr Bishnoi M and the research team at the University Institute of Pharmaceutical Sciences, the phytochemical also may help to reduce the therapeutic doses of conventional NSAIDs and also reduce side effects when used conjunction with nimesulide(144).
In Lipopolysaccharide-Induced Cognitive Impairment in Mice, combination therapy of 3-acetyl-11-keto-β-boswellic acid (AKBA), a 5-lipoxygenase (5-LOX) inhibitor and celecoxib, and a selective cyclooxygenase-2 (COX-2) inhibitor expressed anti-inflammatory activity against amyloid beta peptide (Aβ) induced cognitive dysfunction(145).

Furthermore, oral administration of Boswellic acid inhibited airway hyperresponsiveness, inflammatory cell infiltration, Th2 cytokine and OVA-specific IgE production in a mouse model of asthma by ameliorated the over expression of anti body Th2 cytokines(146).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(143) Boswellia serrata, a potential antiinflammatory agent: an overview by Siddiqui MZ1.(PubMed)
(144) Potentiation of antinociceptive effect of NSAIDs by a specific lipooxygenase inhibitor, acetyl 11-keto-betaboswellic acid by Bishnoi M1, Patil CS, Kumar A, Kulkarni SK.(PubMed)

(145) Co-administration of 3-Acetyl-11-Keto-Beta-Boswellic Acid Potentiates the Protective Effect of Celecoxib in Lipopolysaccharide-Induced Cognitive Impairment in Mice: Possible Implication of Anti-inflammatory and Antiglutamatergic Pathways by Sayed AS1, El Sayed NS2,3.(PubMed)

(146) Boswellic acid attenuates asthma phenotypes by downregulation of GATA3 via pSTAT6 inhibition in a murine model of asthma by Liu Z1, Liu X1, Sang L1, Liu H1, Xu Q1, Liu Z1.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The Phytochemicals: Resveratrol

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

The  Phytochemicals

Different mediators of central inflammation in dysfunctional and inflammatory pain have been found to associate with patient with Fibromyalgia(127). Certain phytochemicals have found effectively for treatment of inflammatory symptoms of patient with FM, including the following

3. Resveratrol
Resveratrol (RES), a well-known antioxidant and anti-inflammatorycompound, is abundant in red wine and exerts numerous pharmacological effects, including hepatoprotection and cadioprotection(137).
The antioxidant exhibited anti-inflammatory effects through ameliorated the expression of proinflammatory (e.g., miR-155) in infections, injuries, atherosclerosis, diabetes mellitus, obesity, cancer, osteoarthritis, age-related macular degeneration, demyelination, and neurodegenerative diseases(138).

In the evaluation of the medical effect of resveratrol, the University of Wuxi, Jiangsu, insisted" Resveratrol prevented the accumulation of chronic oxidative stress and suppression of Tregs production in HFD mice, modulated changes of cytokines in the plasma and spleen, and decreased expressions of inflammatory mediators compared with those of the DIO group"(139).

Furthermore, the antioxidant also expressed anti age-associated chronic diseases through exhibited dysregulation of multiple cell signaling pathways in induction of inflammation(140).According to the University of Arizona study, resveratrol facilitated acute and chronic pain through activation of AMPK, the enzyme played a key role as a master regulator of cellular energy homeostasis(141).
In a Mouse Fibromyalgia-Like Model, resveratrol significantly reduced mechanical allodynia and thermal hyperalgesia in attenuated oxidative stress and reactive species, underlying mechanism of pathogenesis of the disease. through antinociceptive and antidepressant actions(142)

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(137) Resveratrol nanoparticle system improves dissolution properties and enhances the hepatoprotective effect of resveratrol through antioxidant and anti-inflammatory pathways by Lee CW1, Yen FL, Huang HW, Wu TH, Ko HH, Tzeng WS, Lin CC.(PubMed)

(138) Exploring new ways of regulation by resveratrol involving miRNAs, with emphasis on inflammation by Latruffe N1, Lançon A1, Frazzi R2, Aires V1,3, Delmas D1,3, Michaille JJ1, Djouadi F4, Bastin J4, Cherkaoui-Malki M1.(PubMed)

(139) Resveratrol prevents suppression of regulatory T-cell production, oxidative stress, and inflammation of mice prone or resistant to high-fat diet-induced obesity by Wang B1, Sun J, Li X, Zhou Q, Bai J, Shi Y, Le G.(PubMed)

(140) Resveratrol: a multitargeted agent for age-associated chronic diseases by Harikumar KB1, Aggarwal BB.(PubMed)

(141) Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain by Tillu DV1, Melemedjian OK, Asiedu MN, Qu N, De Felice M, Dussor G, Price TJ.(PubMed)

(142) Coadministration of Resveratrol and Rice Oil Mitigates Nociception and Oxidative State in a Mouse Fibromyalgia-Like Model by Peres Klein C1, Rodrigues Cintra M2, Binda N3, Montijo Diniz D3, Gomez MV3, Souto AA4, de Souza AH5.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The Phytochemicals: Curcumin

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                 

 The  Phytochemicals

Different mediators of central inflammation in dysfunctional and inflammatory pain have been found to associate with patient with Fibromyalgia(127). Certain phytochemicals have found effectively for treatment of inflammatory symptoms of patient with FM, including the following

2. Curcumin
Curcumin, a phytochemical found in turmeric used in the Indian cooking recipe has found to process the antioxidants and anti inflammatory effects, epidemiologically.
The phytochemical also showed to inhibited muscle pain, muscle damage, inflammation and delayed onset muscle soreness, the SportsMed Canterbury study suggested.(132), through attenuate the inflammatory responses and production of reactive oxygen species (ROS) that sustain both inflammation and oxidative stress(133).
Dr. Ghosh S and colleagues at the Bose Institute suggested, " Oxidative stress and inflammation play a pivotal role in various diseases like diabetes, cancer, arthritis, Alzheimer's disease and cardiovascular diseases. Curcumin, therefore, could be a therapeutic option for the treatment of these diseases, provided limitations in its oral bioavailability can be overcome."(134), particular in various proinflammatory chronic diseases(135).In fact Dr. Anand P and the research team at the University of Texas M.D. Anderson Cancer Center, curcumin beside inhibited pain in many therapeutic levels but also linked to suppression of inflammation; angiogenesis, tumorigenesis and diseases of the cardiovascular, pulmonary, and neurological systems(136).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(132) Curcumin supplementation likely attenuates delayed onset muscle soreness (DOMS) by Nicol LM1, Rowlands DS, Fazakerly R, Kellett J.(PubMed)
(133) Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial by Drobnic F1, Riera J1, Appendino G2, Togni S3, Franceschi F3, Valle X4, Pons A5, Tur J5.(PubMed)

(134) The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update by Ghosh S1, Banerjee S1, Sil PC2.(PubMed)

(135) Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases by Aggarwal BB1, Harikumar KB.(PubMed)

(136) Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature.by Anand P1, Thomas SG, Kunnumakkara AB, Sundaram C, Harikumar KB, Sung B, Tharakan ST, Misra K, Priyadarsini IK, Rajasekharan KN, Aggarwal BB.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The Phytochemicals: Polyphenols(-)-epigallocatechin-3-gallate (EGCG)

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                  The  Phytochemicals

Different mediators of central inflammation in dysfunctional and inflammatory pain have been found to associate with patient with Fibromyalgia(127). Certain phytochemicals have found effectively for treatment of inflammatory symptoms of patient with FM, including the following

1. Polyphenols(-)-epigallocatechin-3-gallate (EGCG)(Green tea)
Epigallocatechin gallate (EGCG), including catechins, is phytochemicals of Flavan-3-ols, in the group of Flavonoids (polyphenols) found abundantly catechin in green tea.The majoe phytochemical has showed to process anti viral and bacterial effects through immune expression such as chronic or acute inflammation(128). Dr. Xiao J and the research team at the Shenzhen Institute of Advanced Technology suggested, pure extract of (-) epigallocatechin gallate (EGCG) inhibited inflammatory effects through its antioxidant activities against oxidative stress and down regulated pro-inflammatory markers(129).
According to the Universitat de Girona (UdG), Polyphenols(-)-epigallocatechin-3-gallate (EGCG) also showed to reduce pain in attenuate the alterations by diminishing apoptotic gene overexpression in skeletal muscles(130).
In the consideration of the safety amount for healthy individuals to take green tea, Dr. Chow HH and colleagues said, "green tea polyphenol products in amounts equivalent to the EGCG content in 8-16 cups of green tea once a day or in divided doses twice a day for 4 weeks. There is a >60% increase in the systemic availability of free EGCG after chronic green tea polyphenol administration at a high daily bolus dose (800 mg EGCG or Polyphenon E once daily)(131).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(127) Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain--interleukin-8 infibromyalgia and interleukin-1 β in rheumatoid arthritis by Kosek E1, Altawil R2, Kadetoff D3, Finn A4, Westman M2, Le Maître E2, Andersson M5, Jensen-Urstad M6, Lampa J2.(PubMed)
(128) Compounds derived from epigallocatechin-3-gallate (EGCG) as a novel approach to the prevention of viral infections by Hsu S.(PubMed)
(129) Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways by Xiao J1, Ho CT, Liong EC, Nanji AA, Leung TM, Lau TY, Fung ML, Tipoe GL.(PubMed)
(130) (-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury by Renno WM1, Al-Maghrebi M, Al-Banaw A(PubMed)).

(131) Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals by Chow HH1, Cai Y, Hakim IA, Crowell JA, Shahi F, Brooks CA, Dorr RT, Hara Y, Alberts DS.(PubMed)

Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Fibromyalgia -The diet of Circuit fruits

Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                                      Fibromyalgia

Fibromyalgia, according to the American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia in the newly proposed criteria for the classification of fibromyalgia are 1) widespread pain in combination with 2) tenderness at 11 or more of the 18 specific tender point sites(a) as a result in responding to pressure.

                  The diet

Dietary consumption plays an important part in reduce or increase risk of chronic inflammatory diseases. A typical American diet with high amount of red meat, fat and trans fat, processed, meat, artificial ingredients, refined products are associated to promote the expression of pro inflammatory cytokines, leading to all kinds of diseases including chronic inflammatory, cardiovascular diseases and diabetes.

4. Circuit fruits
Circuit fruit contain high amount of Quercetin which can reduce the risk of chronic inflammatory diseases as a result of anti inflammatory(122) and antioxidant effects(123). Vitamin C, also known as L-ascorbate is a water soluble vitamin with a chemical structure formula of C6H6O6 found abundantly in circuit fruit, enhanced the activation of immune cells such as T and NK cells in attenuation of the inflammation caused by viral infection when used conjunction with red ginseng(124).
Dr. Yan H and colleagues in the study of Ascorbic acid (AA) in mitigating oxidative stress and inhibiting inflammation suggested, ascorbic acid significantly reduced clinical signs, inflammatory cytokines, myeloperoxidase (MPO) and malonaldehyde (MDA) activities in animal model(125).

Furthermore, the application of vitamin C and Quercetin, in exposure to fine particulate matter (PM2.5), exhibited the repressive roles in respiratory oxidative damage caused by PM2.5, through attenuated the depleted the cell viability of 16HBE cells, the elevated reactive oxygen species (ROS) generation, and the inhibited mitochondrial genes expressions(126).

                     

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References

(122) In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway by Comalada M1, Camuesco D, Sierra S, Ballester I, Xaus J, Gálvez J, Zarzuelo A.(PubMed)

(123) Health effects of quercetin: from antioxidant to nutraceutical by Boots AW1, Haenen GR, Bast A.(PubMed)

(124) Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection by Kim H1,2, Jang M1, Kim Y1, Choi J1, Jeon J1, Kim J3, Hwang YI1, Kang JS1,2, Lee WJ1.(PubMed)

(125) Ascorbic acid ameliorates oxidative stress and inflammation in dextran sulfate sodium-induced ulcerative colitis in mice by Yan H1, Wang H2, Zhang X3, Li X1, Yu J1.(PubMed)

(126) Amelioration of particulate matter-induced oxidative damage by vitamin c and quercetin in human bronchial epithelial cells by Jin X1, Su R1, Li R2, Song L1, Chen M1, Cheng L3, Li Z4.(PubMed)