Saturday 15 January 2022

Beta-Sitosterol Exerts a Neuro-Protective Effect in Vitro

By Kyle J. Norton

Cancer is a class of chronic diseases associated with irregular cell growth in the tissues of the affected organ.

Brain and spinal cord make up the nervous system. Brain and Spinal Cord tumors originated are not very common.

The function of the brain process a complex function, including control of our thoughts, memory, and speech, movement of the arms and legs,...

Brain cancer is a medical and chronic condition characterized by cell growth disorderly in the brain tissue.

Benign tumors are noncancerous, and malignant tumors are cancerous. More than 190.000 people in the US are diagnosed with a brain tumor each year alone.

A neuron is a nerve cell that forms a building block of the nervous system.

Neuroblastoma is cancer developed by the immature nerve cells found in several areas of the body, mostly in and around the adrenal glands.

Cancer most commonly affects children age 5 or younger compared to less often in older children.

According to the statistics provided by the Cancer Net, approximately 800 children are diagnosed with neuroblastoma in the United States.

And 90% of children affected by neuroblastoma are children younger than 5.

Sadly, the the-5-year survival rate of cancer is less than 50%.

The most common symptoms are totally depending on the area that has been affected including back pain, fever, unexplained weight loss, and bone pain.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of brain cancer, researchers evaluated the neuroprotective effects and action mechanism of Cirsium setidens (CSEA) and Aster scaber (ASEA) against H2O2-induced cell death of human brain neuroblastoma SK-N-SH cells.

According to the experimental and chemical analysis, 
*The major phytochemicals isolated from CSEA and ASEA were found to be β-sitosterol, Dau, Pec, Ast, or isoquercitrin.

* Ethyl acetate fractions from Cirsium setidens (CSEA) and Aster scaber (ASEA) showed neuroprotective effects in SK-N-SH cells.

* Compared to β-sitosterol, pretreatment with Dau, Pec, or Ast showed protective effects against H2O2-induced cell death and inhibited ROS generation by oxidative stress to induce brain cell apoptosis.

In other words, all chemical compounds found in Cirsium setidens (CSEA) and Aster scaber (ASEA) work synergistically by inducing overexpression of free radicals to exert cytotoxicity against the tested cells.

Taken altogether, beta-Sitosterol used in a combination with other chemical compounds may be considered a supplement for the prevention and treatment of brain cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Neuroprotective effects of phytosterols and flavonoids from Cirsium setidens and Aster scaber in human brain neuroblastoma SK-N-SH cells by Chung MJ1, Lee S2, Park YI3, Lee J3, Kwon KH. (PubMed)

Monday 10 January 2022

Herbal Angelica Protects the Neurons Against Traumatic Brain Injury (TBI)

By Kyle J. Norton

The central nervous system containing the brain and the spinal cord is the complex system of nerve tissues that controls the activities of the human body.

It is the center that controls our thoughts, the interpreter of our external environment, and body movement.

Traumatic brain injury (TBI) is a condition caused by sudden damage to the brain due to a blow or jolt to the head. 

Most cases of TBI are associated with car accidence and sports injuries.

The most common symptoms caused by TBI are the loss of consciousness induce-dazed, confusion or disorients, headache, dizziness or loss of balance, difficulty sleeping and the problem with speech

In severe cases, patients may also experience sensory problems, sensitivity to light or sound, memory or concentration problems, mood swings, and feeling depressed or anxious.

Conventionally, the treatment of TBI includes physical therapy, occupational therapy, speech therapy. psychological and vocational counseling, cognitive therapy,... depending on the location of the injury.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

On finding a potential compound for the prevention and treatment of diseases associated with brain injury, researchers examined the effects of Astragali Radix (AR)-Radix Angelica Sinensis (RAS) activity on traumatic brain injury (TBI).

According to the chemical analysis, researchers discover that the effects of the combination against the traumatic brain injury (TBI) may be attributed to the 14 bioactive ingredients in AR-RAS, while 33 potential targets hit by these ingredients related to TBI.

The effectiveness of the combined herbal medicines according to the GO annotation analysis, was involved in the regulation of multiple biological processes by AR-RAS.

Additionally, 89 novel signaling pathways (P<0.05) were also found to underlie the effects of AR-RAS for TBI treatment.

According to the animal experiment, in vivo AR-RAS showed significantly induced tissue recovery and improved neurological deficits in the hippocampus of TBIrats on the 14th day.

More precisely, AR-RAS target the neurotrophin signaling pathways as a major related pathway to improve axonal growth.

Based on the findings, researchers said, "Our work illuminates the "multi-compounds, multi targets, and multi pathways" curative action of AR-RAS in the treatment of TBI by network pharmacology".


Taken altogether, Herbal Angelica used alone or combined with Astragali Radix may be considered a functional herbal medicine for the treatment of traumatic brain injury,  pending a larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A Network Pharmacology Analysis to Explore the Effect of Astragali Radix-Radix Angelica Sinensis on Traumatic Brain Injury by Xie G1, Peng W2, Li P1, Xia Z1, Zhong Y1, He F3, Tulake Y4, Feng D1, Wang Y1, Xing Z. (PubMed)

Saturday 8 January 2022

Healthy Food Coffee and Coffee's Caffeine in Reducing The Risk of Colon Cancer, Studies Reveal

By Kyle J. Norton

Good news for coffee drinkers, coffee consumption regularly is associated with reduced risk of colon cancer, a renowned institute study suggested.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted beans from the Coffea plant, native to tropical Africa and Madagascar.

Colon Cancer is a disease characterized by irregular cell growth in the colon, with the tendency in spreading to distant parts of the body, depending on the stage.

According to the Federico II University of Naples, the efficacy of coffee consumption in attenuated risk of the colon may be attributed to its bioactive components, such as polyphenols, melanoidins, carbohydrates, diterpenes,...

Dr. Vitaglione P, the lead author said, " ...metabolism and composition, both coffee chlorogenic acids and dietary fiber, including melanoidins, may reduce CRC risk, increasing colon motility and antioxidant status".

However, phytochemicals found in coffee may be different that depends on the amount and type of compounds ingested with the beverage, the variety of coffee used, the roasting degree, the type of brewing method as well as the serving size.


Additionally, in the investigated the protective action of coffee against Caco-2 human colon carcinoma cells. researchers filed the following results
1. Even with low concentrations, coffee (<5%) inhibited the proliferation of Caco-2 cells without affecting normal cell viability.
2. . Increasing the duration of coffee bean roasting showed a significant in reduction the mutative risk of gene KRAS expression.

3 Coffee reduces the risk of colon cancer through suppressed miR-30c and miR-96, in promoted cell proliferation, migration and invasion, and enhanced tumor growth.

Interestingly, in the examine of the association between coffee consumption and CRC risk as well as a risk by anatomic subsite among Japanese, using data from the Hospital-based Epidemiological Research Program at Aichi CancerCenter I and II (HERPACC-I and II) with subjects enrolled in HERPACC-I between 1988 and 2000 and in HERPACC-II between 2001 and 2005, scientists found that returned self-administered questionnaire from participants, coffee consumption in reduced risk of colon cancer is associated to numbers of cup intake daily, in compared to non-drinker.

The relative odd ratio of less than 1 cup/day, 1-2 cups/day, and 3 or more cups/day for CRC were 0.88, 0.90, and 0.78 respectively.

Dr. Senda Nakagawa H, the lead author said, " Subsite-specific analysis revealed a significant inverse linear trend between coffee consumption and distal colon cancer (p-trend = 0.048), and a tendency toward a lower risk of rectal cancer (p-trend = 0.068)".

The finding evidence suggested that coffee and coffee caffeine may have a profound effect in reduced risk of cancer linearly.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months



Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Coffee, colon function and colorectal cancer by Vitaglione P1, Fogliano V, Pellegrini N.(PubMed)
(2) Coffee reduces KRAS expression in Caco-2 human colon carcinoma cells via regulation of miRNAs by Nakayama T1, Funakoshi-Tago M1, Tamura H1.(PubMed)

Thursday 6 January 2022

Aloe Vera, the Anti-Microbial Herbal Medicine

By Kyle J. Norton

A recent study performed by a renowned institute suggested that intake of Aloe Vera or Aloe Vera supplement may reduce the risk of microbial infection and infectious diseases.

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan, used in herbal medicine in treating many kinds of disease, including wound, burn- healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterols, etc.

In a total of Sixty students in the age group 6-12 years selected from an orphanage center, divided into four groups study, oral administration of Aloe Vera group showed a decrease of the bacterial count by 80.94% .

Dr. Bhati N, the lead author said, "Herbal dentifrices containing A. Vera... can be safely recommended as an alternative to fluoridated dentifrices in terms of antimicrobial efficacy".

In Streptococcus mutant strains, Aloe vera brushing showed a reduced bacteria contamination of Streptococcus mutant strains, without differentiation from the other chemical agents used.

In fact, Aloe vera in the study against pathogenic such as Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Salmonella Typhimurium, Proteus vulgaris, Klebsiella pneumonia, Escherichia coli, Streptococcus pyogenes and Candida albicans displayed a significantly antimicrobial inhibition rate zones ranging from 6.0 ± 0.57 to 16.6 ± 0.57 mm as the result of the expression of bioactive compounds with high 2,2-diphenyl-1-picrylhydrazyl (DPPH, stable free-radical molecules isolated from the herb), composed of scavenging properties.

Taking together, oral administration of Aloe Vera is found to associate to reduced risk of microbial infection and infectious diseases, but a large amount intake should only be prescribed by related field specialists.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months



Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Evaluation of antimicrobial efficacy of Aloe vera and Meswak containing dentifrices with fluoridated dentifrice: An in vivo study by Bhati N1, Jaidka S1, Somani R1(PubMed)
(2) Antimicrobial capacity of Aloe vera and propolis dentifrice against Streptococcus mutant strains in toothbrushes: an in vitro study by Bertolini PF1, Biondi Filho O, Pomilio A, Pinheiro SL, Carvalho MS.(PubMed)
(3) Diversity, antimicrobial and antioxidant activities of culturable bacterial endophyte communities in Aloe vera by Akinsanya MA1, Goh JK2, Lim SP2, Ting AS3.(PubMed)

Monday 3 January 2022

Omega-3 Fatty Acids Process Anti-Mental Illness in Patients with Omega-3 Fatty Acid Deficiency

By Kyle J. Norton

Neurological disorders are a group of diseases associated with the neurons in the brain and spinal cord of the central nervous system.

The WHO in the evaluation of neurological disorders wrote, "Neurological disorders contribute to 92 million disability-adjusted life years (DALYs) in 2005 projected to increase to 103 million in 2030 (approximately a 12% increase). While Alzheimer's and other dementias are projected to show a 66% increase from 2005 to 2030".

Where one DALY represents the loss of the equivalent of one year of full health.

Believe it or not, there are more than 600 diseases of the central nervous system, including brain tumors, epilepsy, dementia such as Parkinson's disease and Alzheimer's disease, and stroke.

Mental illness is also known as mental health disorders associated with a wide range of mental health disorders, affecting all aspects of your psychological health, including mood, thinking, and behavior.

The most common mental illness in the Western world is depression, anxiety disorders, schizophrenia, eating disorders, and addictive behaviors.

There are many causes associated with the onset of mental illness, including severe psychological trauma suffered as a child, such as emotional, physical, or sexual abuse, an important early loss, such as the loss of a parent, neglect, and poor ability to relate to others.

Medical conditions such as diabetes, a  history of mental illness in a blood relative, such as a parent or sibling, and stressful life situations are some of the prevalent factors that are involved in the onset of the diseases.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of psychological illnesses, researchers examined the effects of omega-3 fatty acids on the prevention and treatment of mental illness.

According to the search of the studies from 1966 to December 2010 by comparing changes in symptoms, functioning, other outcomes, and/or side effects in patients treated with omega-3 fatty acids for mental illness, intake of omega-3 fatty acids showed strong activity against mental illness in patients diagnosed with an omega-3 fatty acid deficiency.

Furthermore, the application of omega 3 fatty acids also have a strong implication against specific psychiatric disorder.

Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of mental illness caused by omega-3 fatty acid deficiency, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The use of omega-3 fatty acids in mental illness by Gören JL1, Tewksbury AT. (PubMed)
(2) The NEURAPRO Biomarker Analysis: Long-Chain Omega-3 Fatty Acids Improve 6-Month and 12-Month Outcomes in Youths at Ultra-High Risk for Psychosis by Amminger GP1, Nelson B2, Markulev C2, Yuen HP2, Schäfer MR2, Berger M2, Mossaheb N3, Schlögelhofer M3, Smesny S4, Hickie IB5, Berger GE6, Chen EYH7, de Haan L8, Nieman DH8, Nordentoft M9, Riecher-Rössler A10, Verma S11, Thompson A2, Yung AR12, McGorry PD. (PubMed)

Sunday 2 January 2022

Phytochemical Tocopherols, the Potential Treatment for Malaria

By Kyle J. Norton

Malaria, a mosquito-borne infectious disease caused by parasitic protozoans.

According to the statistic, malaria is one of the most common diseases in Nigeria, affecting over 97% of Nigeria's population. There are an estimated 100 million malaria cases with over 300,000 deaths per year.

Symptoms of malaria tend to occur in cycles, which correspond to the life cycle of the parasite. The most common symptoms include headaches, fatigue, muscle aches, and gastrointestinal discomforts including diarrhea.

In severe cases, patients with malaria may also experience symptoms of shortness of breath caused by fluid in the lungs and expanded abdomen caused by enlarged spleen hypoglycemia and liver diseases such as jaundice and low blood glucose.

Immune deficiency, pregnant women, newborn babies are prone to the disease if they are bitten by an infected mosquito.

Cerebral malaria is the most severe neurological complication of infection with Plasmodium falciparum malaria.

The condition is caused by coma and asexual forms of the parasite on peripheral blood smears.

Symptoms of cerebral malaria are fever, headache, body ache and progressively, delirium and coma.

Tocopherols are phytochemicals of which many have vitamin E activity, belonging to the group of Lipids, found abundantly in butter, egg yolk, milk fat, some vegetable, and seed or nut oils, etc.

On finding a potential phytochemical for the treatment of diseases associated with parasite infection, researchers examined the effect of α-TOS as an anti-malarial drug.

The study included selected C57BL/6J mice infected with P. yoelii 17XL and P. berghei ANKA, induced cerebral malaria (ECM), treated with several concentrations of α-TOS by intraperitoneal administration on 1, 3, 5, and 7 days post-infection (dpi).

According to the analysis, α-TOS treatment groups showed a significant decrease in parasitemia and improvement of the survival rate compared to a significant increase in mice infected with both parasites. 

Furthermore, the intensity of Evans blue staining associated with plasma membrane damage on brains taken from α-TOS-treated mice was weaker than that of untreated mice. 

In other words, α-TOS treatment exerted an inhibition of the breakdown of the blood-brain barrier (BBB) and the progression of cerebral malaria. 

Based on the findings, researchers said, " These findings indicate that vitamin E derivatives like α-TOS might be a potential candidate for treatment drugs against malaria"

Taken altogether, tocopherols may be considered a supplement for the treatment of malaria, pending to the confirmation of the larger sample size and multicenter human study.

Intake of tocopherols in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) α-Tocopheryl succinate-suppressed development of cerebral malaria in mice by Kume A1, Kasai S2, Furuya H1, Suzuki H. (PubMed).

Thursday 30 December 2021

Herbal Dandelion (Taraxacum officinale), a Natural Anti-Colitis Remedy

By Kyle J. Norton

Colitis is medical a condition characterized by the inflammation of the large intestine, including the colon, caecum, and rectum.

Depending on the causes, colitis can be classified into microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis, and Behcet's colitis, particularly in those associated with inflammatory bowel disease (IBD), such as ulcerative colitis (UC).

* Inflammatory bowel disease (IBD) is the inflammation of chronic inflammation of digestive tract associated with symptoms of severe diarrhea, abdominal pain, fatigue, and weight loss.

* Microscopic colitis is a disease involved in the inflammation of the colon or large intestine, associated with symptoms of watery diarrhea and cramping. Microscopic colitis is much less severe than other types of inflammatory bowel disease.

* Ischemic colitis is an inflammation of the large intestine caused by the injury-induced inadequate blood supply to the colon, leading to pain on the left side of the abdomen.

* Segmental colitis associated with diverticula is an inflammation that affects colonic luminal mucosa in segments due to diverticulosis, causing symptoms of bloody stools, sometimes accompanied by abdominal pain, cramping discomfort, or diarrhea.

* Radiation colitis is an inflammation of the large intestines in patients with radiation therapy, leading to symptoms of diarrhea, nausea, vomiting, and stomach cramps.

* Diversion colitis is an inflammation of the large intestines as a complication of ileostomy or colostomy. Most cases of diversion colitis often occur within the year following the surgery.

* Eosinophilic colitis is a rare disease associated with a type of white blood cell, due to injury and inflammation to the large intestine.

* Behcet's colitis is chronic immune-mediated, inflammatory disorder that only affect the intestines but also the joints, skin, eyes, and biliary tracts

Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.

On finding a natural ingredient for the prevention and treatment of inflammatory diseases, scientists examined the taraxacum officinale extract (TOE) effects on colitis.

According to the results of DSS-induced colitis treated with different concentrations of TOE for 8 days, TOE showed significant activity in the attenuation of the clinical symptoms, by lowering the inflammatory scoring and inhibiting the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

In other words, the efficacy of TOE in the treatment of colitis was associated with the activity in the induction of fatty acid degradation through the increased of the expression levels of Adh5, Aldh3a2, and Acox in breaking down fat and decreased the levels of CCL20, CCR6, and CXCL1 in cytokine-receptor signaling.

Additionally, TEO also enhanced the levels of S24-7 and adlercreutzia but decreased the number of anerostipes, Enterococcus, Enterobacteriaceae and peptostreptococcaceae to promote microbial imbalance or maladaptation

Based on the findings, researchers said, "TOE ameliorated DSS-induced colitis by regulating fatty acid degradation and microbial dysbiosis".

Taken altogether, dandelion may be considered a remedy for the protection against colitis, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Taraxacum officinale extract ameliorates dextran sodium sulphate-induced colitisby regulating fatty acid degradation and microbial dysbiosis by Chen W1, Fan H1, Liang R1, Zhang R1, Zhang J1, Zhu J. (PubMed)