Sunday, 23 July 2023

#Herbal #Turmeric and Ginger Exert a Significant Protection of Endocrine Functioning by Modulating the Hormones Produced by the Glands

Kyle J. Norton

Scientists may have found a bioactive ingredient that protects the endocrine system integrity with no side effects, according to studies.

The endocrine system is made up of glands that produce and secrete hormones with the aim to regulate the activity of cells or organs.

In other words, the endocrine system produces hormones to regulate the body's growth, metabolism (the physical and chemical processes of the body), and sexual development and function.

Any disruption of the endocrine system can cause abnormal production of hormones, leading to developmental malformations in the infant and children, interference with the function of the reproductive organ, increased cancer risk; and disturbances in the immune and nervous system function.

The most common cause of endocrine dysfunction is exposure to man-made xenochemiclas. Particularly to those new and without testing men make chemicals introduced to the market every year.

There are many ways that endocrine disruptors can interfere with the endocrine system in hormone production such as mimic or partly mimic naturally occurring hormones in the body like estrogens such as xanophytochemicals that bind to a receptor within a cell and block the endogenous hormone from binding.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.


The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

With an aim to find a natural ingredient that promotes endocrine function, researchers examined the effects of ginger and turmeric on the modulation of hormone production in the body's glands.

According to the differentiation of physiological and therapeutic effects of ginger and turmeric, both exerted a significant activity in some endocrine gland functions, and signal pathways by
* Inhibiting the high levels of some hormones such as T4, leptin or interacting with hormone receptors. In other words, ginger and turmeric normalize the levels of the hormone for the body needs.

* Inhibiting the production of cytokines/adipokine expression associated with inflammation and oxidative stress.

* Inhibiting the levels of reactive oxygen species (ROS)-generating enzymes against the oxidative stress-induced hormone imbalance.


* Protecting the cell integrity against DNA alternation by promoting pro-apoptotic and inhibiting proliferative genes.

The results strongly suggested that ginger and curcumin exerted strong protection of endocrine functioning by modulating the hormones produced by the glands.

Based on the findings, researchers said, "These multiple mechanisms of protection against inflammation and oxidative damage make ginger and curcumin particularly promising natural agents in fighting the ravages of aging and degenerative diseases".

Taken together, turmeric combined with ginger may be considered supplements for the prevention and treatment of endocrine dysfunction, pending the confirmation of the larger sample size and multicenter human study.

Intake of turmeric and ginger in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Physiological and therapeutical roles of ginger and turmeric on endocrine functions by Al-Suhaimi EA1, Al-Riziza NA, Al-Essa RA. (PubMed)
(2) [Effect of 5 warm-hot nature Chinese drugs for promoting blood circulation and removing blood stasis on 5-HT, NE, and endocrine hormones of rats of cold coagulation and blood stasis syndrome].[Article in Chinese] by Wang P1, Fu XJ, Zhou Y, Wang ZG. (PubMed)

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