Whole Food Cucumber Inhibits All Parameters Associated with Insulin Resistance In Vivo

By Kyle J. Norton

Insulin Resistance, a hallmark in patients with type II diabetes is the condition in which the cells in tissues that start to resist or ignore the signal of the hormone insulin.

In other words, the insulin produced by the body no longer can convert glucose to energy even with the presence of the hormone insulin, leading to high levels of glucose in the bloodstream.

According to the statistics provided by the CDC, approximately, 1 in 3 people in the United States have prediabetes, including half of those age 60 and older.

People with insulin resistance has been found to increase the risk for prediabetes, type 2 diabetes and other serious health problems, such as cardiovascular disease and cancer.

Although researchers do not know the exact cause of insulin resistance, they do not certain risk factors such as genetic preposition, aging, and ethnicity are associated with the onset of the condition.

However, an unhealthy lifestyle that causes excess body weight, too much belly fat, smoking and lack of exercise are the most prevalent factors in the Western world.

Dr. Martin O. Weickert wrote, "Insulin resistance has been proposed as the strongest single predictor for the development of Type 2 Diabetes (T2DM). Chronic oversupply of energy from food, together with inadequate physical activity, has been recognized as the most relevant factors leading to overweight, abdominal adiposity, insulin resistance, and finally T2DM".

And, "Conversely, energy-reduced diets almost invariably to facilitate weight loss and reduce abdominal fat mass and insulin resistance. However, sustained weight loss is generally difficult to achieve, and distinct metabolic characteristics in patients with T2DM further compromise success".

The findings strongly suggested that by maintaining a healthy lifestyle including a healthy diet and moderate exercise, insulin resistance is preventable.

The cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.

On finding a potential compound for the treatment of insulin resistance, researchers investigated the effect of the effects of Cucumis melo L. (Cucumis) on obesity-induced insulin resistance (IR) in genetically leptin-deficient Lepob/Lepob mice.

According to the results of the tested assays, Cucumis showed significant activity in the improvement of IR in obese mice and inhibition of inflammation in adipose tissue and blood.

The efficacy of Cucumis against insulin resistance of the tested mice was also attributed to the enhancement of the ratio of gut microbiota in the gut associated with improvement of insulin sensitivity.

Based on the findings, researchers wrote in the final report, " administration of Cucumis improved IR by reducing inflammation, thereby changing the gut microbiota composition. Cucumis is thus a promising treatment for obesity-induced insulin resistance and the inflammatory state".

The Lund University in the study of glycemic and insulinemic responses to fermentation products suggested that adding pickled cucumber to breakfast with a high-glycemic index bread significantly lowered postprandial glycemia and insulinemia compared to no metabolic response of regular milk and fresh cucumber.

In other words, fermentation products such a prickle play an essential role in reducing the risk of insulin resistance.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Taken altogether, fermented cucumber may be used for the treatment of insulin resistance, pending to the confirmation of the larger sample size and multicenter human study.
Sources
(1) Therapeutic Effect of Cucumis melo L. Extract on Insulin Resistance and the Gut Microbiome in Lepob/Lepob Mice by Lee D1, Yoo JH1, Lee BC. (PubMed)
(2) Inconsistency between glycemic and insulinemic responses to regular and fermented milk products by Ostman EM1, Liljeberg Elmståhl HG, Björck IM. (PubMed)
(3) Nutritional Modulation of Insulin Resistance by Martin O. Weickert. (PMC)