Food Therapy: Maternal Coffee Intake in Reduced Risk of β-cell autoimmunity in New Born

By Kyle J. Norton

In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Maternal consumption of coffee may have a profound effect in reduced risk of β-cell autoimmunity inducing Type 1 diabetes in the offspring, according to the University of Tampere.

In a prospective Finnish birth cohort of 4297 infants with human leukocyte antigen (HLA)-DQB1-conferred susceptibility to type 1 diabetes with lbood samples collected from the children at 3-12 months intervals to measure type 1 diabetes-associated antibodies against islet cells (ICA), insulin, glutamate dehydroxylase, and islet antigen 2, returned questionnaire from mothers indicated that intake of coffee during perchance expresses a inversely associated risk of development of advanced β-cell autoimmunity in their infants.

Even after adjusting to other risk factors,  coffee showed a linearly dependent to amount of cups intake of the mothers against risk of β-cell autoimmunity incidence in newborns.

Additionally, in the review of data comprised 4297 children with increased genetic susceptibility to type 1 diabetes, born at the University Hospital of Oulu or Tampere, Finland, between October 1997 and December 2002 monitored for diabetes-associated autoantibodies from samples obtained at 3-12-mo intervals, returned surveys from mothers indicated that coffee increased antioxidant status have a a significant effect in reduced risk of advanced beta cell autoimmunity development in children, compared to substantial risk of the offspring in mother who did not intake any antioxidant dietary nutrients.

Further more, Dr. Uusitalo L, the lead researcherssaid, "the hazard ratios, indicating the change in risk per a 2-fold increase in the intake of each antioxidant, were nonsignificant and close to 1" and "High maternal intake of retinol, beta-carotene, vitamin C, vitamin E, selenium, zinc, or manganese does not protect the child from development of advanced beta cell autoimmunity in early childhood".

Interestingly, the returned questionarre from participants in the data from a population-based case-control study with incident cases of adult onset (≥ 35 years) diabetes, including 245 cases of latent autoimmune diabetes in adults (glutamic acid decarboxylase antibody positive), 759 cases of Type 2 diabetes (glutamic acid decarboxylase antibody negative), together with 990 control subjects without diabetes, randomly selected from the population, researchers found that intake of coffee may have enormous effect in reduced risk of type 2 diabetes, but conversely, coffee intake showed to associate to elevated risk of autoimmunity and possibly an increased risk of Type 1-like latent autoimmune diabetes in these group of adults.

Dr. Löfvenborg JE, the lead author in above study said, " for every additional cup of coffee consumed per day, there was a 15.2% (P = 0.0268) increase in glutamic acid decarboxylase antibody levels".

Taking altogether, There is no doubt that coffee consumption during pregnancy has a substantial effect in attenuated risk of type 1 diabetes caused by advanced β-cell autoimmunity. But coffee consumed in adulthood may increased risk of  Type 1-like latent autoimmune diabetes adults. contrastively.

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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Maternal food consumption during pregnancy and risk of advanced β-cell autoimmunity in the offspring by Virtanen SM1, Uusitalo L, Kenward MG, Nevalainen J, Uusitalo U, Kronberg-Kippilä C, Ovaskainen ML, Arkkola T, Niinistö S, Hakulinen T, Ahonen S, Simell O, Ilonen J, Veijola R, Knip M.(PubMed)
(2) Intake of antioxidant vitamins and trace elements during pregnancy and risk of advanced beta cell autoimmunity in the child by Uusitalo L1, Kenward MG, Virtanen SM, Uusitalo U, Nevalainen J, Niinistö S, Kronberg-Kippilä C, Ovaskainen ML, Marjamäki L, Simell O, Ilonen J, Veijola R, Knip M.(PubMed)
(3) Coffee consumption and the risk of latent autoimmune diabetes in adults--results from a Swedish case-control study by Löfvenborg JE1, Andersson T, Carlsson PO, Dorkhan M, Groop L, Martinell M, Rasouli B, Storm P, Tuomi T, Carlsson S.(PubMed)