Premenstrual Syndrome(PMS) caused by Liver Qi stagnation in Chinese Herbs Perspective

 By Kyle J. Norton 
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Premenstrual syndrome effects over 70% to 90% of women before menopause in the US and less for women in Southeast Asia because of their difference in living style and social structure. It is defined as faulty function of the ovaries related to the women's menstrual cycle, it effects a women's physical and emotional state, and sometimes interferes with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts. In this article, we will discuss How Traditional Chinese Medicine Helps to Treat PMS.

Traditional Chinese medicine used over 4000 thousand years in treating women reproductive system disorder believed Pre menstrual syndrome is also caused by Liver Qi Stagnation in many cases.

Liver is important in carbohydrate synthesis and fat and protein metabolism(1). Liver qi stagnation causes abnormal function of liver in regulating the production of estrogen(2) and other hormones by glands(2) for controlling menstrual blood(3), leading to blood stagnation in the productive system and inducing symptoms of premenstrual syndrome including irritability, anger, depression(4)(5), etc,.

1. Angelica synthesis (Dang Qui)
Angelica synthesis, a queen herb for women reproductive tonic, has been used in traditional Chinese medicine in treating all women productive disorder(6) by releasing the qi stagnation cause of blood stasis(7) including pre menstrual syndrome. probably through its phytochemicals estrogenic(8)(9) and antiestrogenic(10) activities in restored hormone imbalance before ovulation and inhibited the over active uterus muscles(11)(12)(13) cause of pre menstrual pain and cramps(14)(15) and irregular menstruation(15).

2. Milk thistle seed
Milk thistle seed used in the traditional Western medicine over thousand year for liver tonic, showed to restore the liver qi stagnation caused by environment toxins and other toxins(16) and regenerate the liver's cells(16) in reduced symptoms of PMS(17) caused by the changes in monoamine neurotransmitters(17)

3. Peony (Shao Yao)
White peony showed to sooth liver qi stagnation(18) through a blood purifier and induced blood flow by increasing the liver in blood formation(19) and nourishing menstruation(20), relaxing spasm(22), relieving pain(22) and  liver dysfunction(20) causes of tension of nervous system, such as anxiety(23)

4. Fennel seed (Xiao Hu Xiang)
Fennel seed released the stagnation caused by imbalance of yin yang qi in the liver(24) causes of reduced blood flow in inhibition symptoms of pain and cramps(25).

5. Yellow dock root
Yellow dock root, a liver tonic medicine(26), detoxifies liver by removing oxidative damage accumulated in the liver(27) induced liver dysfunction in regulating the production of hormones(2) before and after ovulation.
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References
(1) Vodka and wine consumption in a swine model of metabolic syndrome alters insulin signaling pathways in the liver and skeletal muscle. Elmadhun NY1, Lassaletta AD, Chu LM, Bianchi C, Sellke FW.(PubMed)
(2) http://en.wikipedia.org/wiki/Estrogen
(3) http://www.ncbi.nlm.nih.gov/pubmed/23822457
(4) http://www.ncbi.nlm.nih.gov/pubmed/25211539
(5) http://www.ncbi.nlm.nih.gov/pubmed/20450050
(6) Dang Gui (Chinese Angelica Root) - Chinese Herbal Medicine
(7) http://www.ncbi.nlm.nih.gov/pubmed/21315572
(8)Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease by Choi RC¹, Zhu JT, Yung AW, Lee PS, Xu SL, Guo AJ, Zhu KY, Dong TT, Tsim KW.(PubMed)
(9) Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death by Zhu JT¹, Choi RC, Chu GK, Cheung AW, Gao QT, Li J, Jiang ZY, Dong TT, Tsim KW.(PubMed)
(10) Isoflavones: chemistry, analysis, functions and effects on health and cancer by Ko KP.(PubMed)
(11) http://www.ncbi.nlm.nih.gov/pubmed/20195064
(12) http://www.ncbi.nlm.nih.gov/pubmed/12802720
(13) http://www.ncbi.nlm.nih.gov/pubmed/16573009
(14) http://www.ncbi.nlm.nih.gov/pubmed/23729340
(15) http://www.ncbi.nlm.nih.gov/pubmed/23883364
(16) http://www.ncbi.nlm.nih.gov/pubmed/20564545
(17) http://www.ncbi.nlm.nih.gov/pubmed/22883410 
(18) http://www.ncbi.nlm.nih.gov/pubmed/22779188
(19) Hemopoietic effect of extracts from constituent herbal medicines of Samul-tang on phenylhydrazine-induced hemolytic anemia in rats by Lee HW¹, Kim H¹, Ryuk JA¹, Kil KJ², Ko BS¹.(PubMed)
(20) Characterization of the anti-influenza activity of the Chinese herbal plant Paeonia lactiflora by Ho JY¹, Chang HW², Lin CF³, Liu CJ⁴, Hsieh CF⁵, Horng JT⁶(PubMed)
(21) Anti-viral activity of water extract of Paeonia lactiflora pallas against human respiratory syncytial virus in human respiratory tract cell lines by Lin TJ¹, Wang KC, Lin CC, Chiang LC, Chang JS.(PubMed)
(23) Anxiolytic-like effect of paeonol in mice by Mi XJ¹, Chen SW, Wang WJ, Wang R, Zhang YJ, Li WJ, Li YL.(PubMed)
(24) http://www.ncbi.nlm.nih.gov/pubmed/25211539
(25) http://www.ncbi.nlm.nih.gov/pubmed/?term=fennel+seed+and+pain
(26) http://www.ncbi.nlm.nih.gov/pubmed/23766852
(27) http://www.ncbi.nlm.nih.gov/pubmed/17517459