Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to the
northern North America, Asia and Europe. The herb has been used in
traditional medicine as diuretic agent and to treat urinary problems,
including bladder infections, kidney infection, kidney stone, pelvic
pain, etc.
Inflammation is a condition of Immune
system self-protection to remove harmful stimuli, including damaged
cells, irritants, pathogens... from our body.
The Ingredients It contains
arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and
resin, hydroquinones tannins, phenolic glycosides and flavonoids.
The benefits
Water extract (UW-ext) collected from the the leaf of Arctostaphylos uva-ursi (L.) Spreng (Bearberry
leaf), is found to exhibit its anti-inflammatory effects in ear
swelling by picryl chloride-induced contact dermatitis (PC-CD) and
carrageenin-induced paw edema. arbutin isolated from the leaves of Arctostaphylos
uva-ursi (L.) Spreng., when combined with and indomethacin on Type IV
allergic reaction-induced immuno-inflammation, carrageenin-induced edema
and adjuvant-induced arthritis, found to be effective as arbutin may
increase the inhibitory action of indomethacin on PC-CD, SRBC-DTH,
carrageenin-induced edema and adjuvant-induced arthritis, but further
investigations are required to understand the mechanism involved. Other
study also indicated that 50% methanolic extract (U-ext), containing
arbutin, possesses a therapeutic effect against immuno-inflammation
induced by by picryl chloride (PC-CD) and also increases the inhibitory
effect of prednisolone.
The Side effect
1. Overdoses may cause gastrointestinal
discomfort, including cause nausea, vomiting, etc. and fever, chills,
severe back pain, ringing in the ears, etc.
2. The herb may interact with other medicine, including diuretic
3. Do not use the herb in new born,
children or if you are pregnant or breast feeding without approval from
the related field specialist.
4. Etc.
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References
(1) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. V. Effect of water extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry
leaf) on the antiallergic and antiinflammatory activities of
dexamethasone ointment].[Article in Japanese] by Matsuda H, Nakamura S,
Tanaka T, Kubo M.(PubMed)
(2) [Pharmacological studies on leaf of Arctostaphylos
uva-ursi (L.) Spreng. III. Combined effect of arbutin and indomethacin
on immuno-inflammation].[Article in Japanese] by Matsuda H, Tanaka T,
Kubo M.(PubMed)
(3) [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. I. Combined effect of 50% methanolic extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) and prednisolone on immuno-inflammation].[Article in Japanese] by Kubo M, Ito M, Nakata H, Matsuda H.(PubMed)
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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