Kyle J. Norton
Green tea may be considered as a functional food in lower risk and treatment for patients with nonalcoholic fatty liver disease, a respectable institute opinionated.
Non-alcoholic Fatty Liver Disease is a condition caused by over accumulated of fat in the liver.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will solve the aversion.
According to the University of Connecticut, Storrs, the efficacy of green tea for the treatment of obese patients with nonalcoholic fatty liver disease is associated with polyphenolic catechins in the induction of hypolipidemic, thermogenic, antioxidant, and anti-inflammatory activities.
These chemical compounds have also been found to mitigate the occurrence and progression of NAFLD.
Dr. Masterjohn C, the lead author said, "(The phytochemical compounds) demonstrating the hepatoprotective properties of green tea and its catechins and the proposed mechanisms by which these targeted dietary agents protect against NAFLD"
Furthermore, in mice fed on a high-fat diet for 24 weeks., then injected with EGCG (10, 20 and 40 mg·kg(-1)·d(-1), ip), for 4 weeks, researchers found that treated mice showed a significant improvement of a high-fat diet in induced the body weight, grade 2 or 3 liver fatty degeneration (steatosis, lobular inflammation, and ballooning), severe hyperlipidemia, hyperglycemia, hyperinsulinemia, and insulin resistance.
The phytochemical EGCG, in dose-dependent, also enhanced insulin clearance and upregulated IDE protein expression and enzyme activity in regulated levels of glucose in the liver of treated mice.
In fact, EGCG not only promoted weight loss but also attenuated symptoms of mice with nonalcoholic fatty liver disease.
Promisingly, in the study of green tea polyphenols (GTP) on non-alcoholic fatty liver disease (NAFLD) in Zucker fatty (ZF) rats, researchers also indicated that GTP intervention not only decreased weight gain and significantly lowered visceral fat but also reduced fasting serum insulin, glucose and lipids levels, through ameliorated expression of hepatic TG accumulation and cytoplasmic lipid droplet as well as diminished hepatic lipogenesis and triglycerides outflux from liver.
Taken together, green tea has expressed a significant enhancement in reduced risk and treatment of
nonalcoholic fatty liver disease, through many aspects. However large amounts of intake regularly should be taken with care to prevent toxicity.
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Sources
(1) Therapeutic potential of green tea in nonalcoholic fatty liver disease by Masterjohn C1, Bruno RS.(PubMed)
(2) Green tea polyphenol epigallocatechin-3-gallate ameliorates insulin resistance in non-alcoholic fatty liver disease mice by Gan L1, Meng ZJ1, Xiong RB2, Guo JQ1, Lu XC1, Zheng ZW1, Deng YP1, Luo BD1, Zou F3, Li H1.(PubMed)
(3) Green tea polyphenols ameliorate non-alcoholic fatty liver disease through upregulating AMPK activation in high fat fed Zucker fatty rats by Tan Y1, Kim J1, Cheng J1, Ong M1, Lao WG1, Jin XL1, Lin YG1, Xiao L1, Zhu XQ1, Qu XQ1.(PubMed)
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