Beta-Sitosterol Reduces the Risk and Onset of Tuberculosis

By Kyle J. Norton

The lung is a vital organ of the human being, located near the backbone on either side of the heart with functions of inhaling oxygen from the air then transporting them to the bloodstream to nourish the body cells' need and exhaling carbon dioxide from the bloodstream.

Chronic respiratory diseases are the medical conditions related to abnormal function of the airways and other parts of the lung.

Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis. Commonly, the bacterium attacked the lung tissue but in some cases, it also can cause major damage to other parts of the body.

The disease is very contagious, as types of bacteria that cause TB can spread from person to person through microscopic droplets released into the air.

In other words, people can be infected by TB if they can to close contact with TB patients through tuberculosis coughs, speaks, sneezes, spits,.... and laughs.

The disease is rare in the Western world, however, according to the report of WHO of the region including 36 countries in the Western Pacific Region, approximately 1.4 million notified cases of all forms of TB in 2011 (75 per 100 000 population), corresponding to 23% of the total cases notified globally.

There were 0.6 million new smear-positive cases notified in 2011 (32 per 100 000 population), corresponding to 22% of the total smear-positive cases notified globally.

Most common TB complication has been recorded are spinal pain, back pain, and stiffness, joint damage. 

Furthermore, depending on the diseases associated with the complication induced by tuberculous, patients may also experience the hips and knees malformation, swelling of the membranes that cover your brain, liver or kidney problems, and heart disorders.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of infectious diseases, researchers examined the adjuvant effect of beta-sitosterol and its glucoside in the treatment of culture-proven pulmonary tuberculosis (PTB).

The blinded randomized placebo-controlled trial was conducted by using the culture-proven drug-sensitive PTBs from patients hospitalized for the duration of treatment.

According to the chemical analysis,
* Weight gain was significantly greater in the sitosterol group (mean weight gain 8.9 kg) compared to placebo.

* However, the speed of achieving culture negativity, radiological improvement and induration on Mantoux testing was similar in the two groups.

* Most importantly, the sitosterol treatment group demonstrated a significant increase of lymphocyte counts and eosinophil counts from baseline compared to placebo.

Collectively, scientists suggested, "The study has shown significantly improved weight gain and higher lymphocyte and eosinophil counts in PTB patients receiving sitosterols in addition to an efficacious antituberculosis regimen".

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of tuberculosis, pending to the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A randomised placebo-controlled trial of the efficacy of beta-sitosterol and its glucoside as adjuvants in the treatment of pulmonary tuberculosis by Donald PR1, Lamprecht JH, Freestone M, Albrecht CF, Bouic PJ, Kotze D, van Jaarsveld PP. (PubMed)