Omega -3 Fatty Acids Reduces the Risk of Type 2 Diabetes in Overweight or Obese

By Kyle J. Norton

Diabetes is a chronic and medical condition characterized by the inability of the body to use insulin to convert glucose in the bloodstream to energy.

Type 2 diabetes or acquired diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate glucose due to either cell in the pancreas dying off or receptor sites clogged up by fat and cholesterol.

Researchers do not know what causes the pancreas dying off or receptor sites clogged up. However, they do know obesity or overweight, gender, ethnicity, age, family history, gestation diabetes, are associated with an increased risk of type 2 diabetes.

Some researchers also suggested that people with certain medical conditions such as polycystic ovary syndrome. and high blood pressure is more prone to the onset of the disease.

The most common symptoms of type 2 diabetes are increased thirst that won't stop with water intake, increased hunger (especially after eating), dry mouth, frequent urination, and unintentional weight loss.

According to statistics, diabetes is one of the most common diseases in the US. Approximately 10% or 29.1 million people in the United States have diabetes, accompanied by 8.1 million that are undiagnosed and unaware of their condition.

About 1.4 million new cases of diabetes are diagnosed in the United States every year. More than one in every 10 adults who are 20 years or older has diabetes.

Diabetic complications are any diseases associated with hyperglycemia if the blood glucose is not managed properly. Patients with diabetes may induce a number of complications including cardiovascular disease, neuropathy, nephropathy, retinopathy, and foot ulcer.

Overweight, blood pressure and cholesterol are some of the conditions associated with increased risk of diabetes complications.

By managing your blood glucose properly and daily, the risk of diabetic complications can be reduced in diabetics by taking your medication as directed, keeping tight control of your blood sugar or managing the blood glucose in the required range, eating healthy with moderate exercise to protect your weight, blood pressure, and cholesterol, get regular checkups and quit smoking

If you are following the aforementioned suggestion, you may do just fine in the prevention of diabetes complications.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the Long-chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) status on patients with type 2 diabetes in the Hunter Community Study.

The study included men and women aged 55-85 years (n = 2092, diabetes: n = 249) who had plasma phospholipid fatty acid composition data available and diabetes status randomly selected from the electoral roll and invited to participate.

According to the tested analysis, after adjusting for confounders of diabetes, 

* LCn-3PUFA status was inversely associated with diabetes in overweight/obese females (OR [95%CI]: 0.90 [0.80, 1.00], p = 0.045) but not males (p-interactionsex = 0.041).

* Furthermore, overweight/obese females with diabetes had significantly lower levels of DHA than those without diabetes (mean difference [95%CI]: -0.53 [-0.87, -0.20], p = 0.002), with no difference in EPA.

In other words, low levels of DHA are associated with patients with diabetes regardless of weigh.

* More importantly, LCn-3PUFA was inversely associated with Homeostatic model assessment-Insulin Resistance  (HOMA-IR) (r = -0.175, p = 0.005).

Based on the evidence, researchers said, "This study provides further evidence of a sex-dependent association between LCn-3PUFA and types 2 diabetes. Causal pathways between LCn-3PUFA and type 2 diabetes merits delineation".

Taken altogether, Omega-3 fatty acids processed abundantly LCn-3PUFA  may be considered a functional food for the prevention and treatment of type 2 diabetes, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Association between plasma phospholipid omega-3 polyunsaturated fatty acids and type 2 diabetes is sex dependent: The Hunter Community Study by Abbott KA1, Burrows TL2, Thota RN3, Alex A1, Acharya S4, Attia J5, McEvoy M5, Garg ML. (PubMed)
(2) Curcumin and/or omega-3 polyunsaturated fatty acids supplementation reduces insulin resistance and blood lipids in individuals with high risk of type 2 diabetes: a randomised controlled trial by Thota RN1,2, Acharya SH3, Garg ML. (PubMed)