Testosterone is a male hormone. The hormone besides promoting libido it has other important functions such as maintaining muscle mass and forming bone and regulating heart muscle and cholesterol.
The Hormone also helps to improve the oxygen levels throughout the body as well as controlling blood glucose and strengthening the immune system.
However, as men age, the pituitary gland produces less free testosterone while more free testosterone is being converted to estrogen which results in many health problems.
Testosterone is synthesized primarily in Leydig cells stimulated by the pituitary gland to release FSH and LH.
* Loss of bone density
The brain and bone are the important issues that have the primary effect of testosterone are by way of aromatization to 17² estradiol in the bones. 17²-estradiol accelerates the maturation of cartilage into bone, leading to the closure of the epiphyses (a rounded end of a long bone) and a conclusion of growth.
* Loss of muscle mass
Testosterone effects can be classified as anabolic effects that include growth of muscle mass and strength, increased bone density and strength, and stimulation of height growth and bone maturation. Testosterone effects can also be classified by the age of usual occurrence.
* Memory loss
Low levels of testosterone allow beta-amyloid, a toxic peptide to accumulate in certain regions of the brain causing memory loss.
* Abdominal fat
Fat cells create aromatase enzymes that contribute to fat build up and low levels of testosterone which allows the forming of abdominal fat that produces more aromatase enzymes resulting in more formation of estrogen. It also causes insulin resistance by increasing fat around the stomach/waist area and fat mass.
Testosterone is synthesized primarily in Leydig cells stimulated by the pituitary gland to release FSH and LH.
In other words, when the levels of testosterone are low, testosterone is synthesized induced by gonadotropin-releasing hormone (GnRH) that is released by the hypothalamus.
Symptoms associated with testosterone deficiency are
* Decreased sexual function
As we mentioned in the last article, starting at age 40 levels of testosterone start to diminish. The levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to dihydro-testosterones DHT thus triggering low levels of testosterone resulting in sexual dysfunction.
As we mentioned in the last article, starting at age 40 levels of testosterone start to diminish. The levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to dihydro-testosterones DHT thus triggering low levels of testosterone resulting in sexual dysfunction.
* Loss of bone density
The brain and bone are the important issues that have the primary effect of testosterone are by way of aromatization to 17² estradiol in the bones. 17²-estradiol accelerates the maturation of cartilage into bone, leading to the closure of the epiphyses (a rounded end of a long bone) and a conclusion of growth.
* Loss of muscle mass
Testosterone effects can be classified as anabolic effects that include growth of muscle mass and strength, increased bone density and strength, and stimulation of height growth and bone maturation. Testosterone effects can also be classified by the age of usual occurrence.
* Memory loss
Low levels of testosterone allow beta-amyloid, a toxic peptide to accumulate in certain regions of the brain causing memory loss.
* Abdominal fat
Fat cells create aromatase enzymes that contribute to fat build up and low levels of testosterone which allows the forming of abdominal fat that produces more aromatase enzymes resulting in more formation of estrogen. It also causes insulin resistance by increasing fat around the stomach/waist area and fat mass.
Impairment of testosterone synthesis is a condition associated with the testis impaired by the cryptorchid state,
The study included 75 12-week-old male Sprague-Dawley rats that were randomly divided into 5 groups, containing 15 rats each: a normal control group that received no treatment and 4 experimental groups (I, II, III, and IV) in which an LHRH agonist was administered for 4 weeks to induce spermatogenic failure. Group I received distilled water, and groups II, III, and IV received 200 mg/kg/day of KH-465, 400 mg/kg/day KH-465, and depo-testosterone for 4 weeks, respectively.
On finding a natural ingredient for the prevention and treatment of cancers, scientists examined the Chinese angelica polysaccharide (CAP), the main effective ingredient of angelica sinensis anti-inflammatory and anti-apoptotic effects.
Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a potential compound for the treatment of male infertility, researchers examined the protective effect of a mixture of 2 herbal extracts, KH-465, which consisted of Epimedium koreanum Nakai and Angelica Gigas Nakai, on spermatogenesis in a luteinizing hormone-releasing hormone (LHRH) agonist-induced rat model of male infertility.
Angelica or Dang Gui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a potential compound for the treatment of male infertility, researchers examined the protective effect of a mixture of 2 herbal extracts, KH-465, which consisted of Epimedium koreanum Nakai and Angelica Gigas Nakai, on spermatogenesis in a luteinizing hormone-releasing hormone (LHRH) agonist-induced rat model of male infertility.
According to the results of differentiation,
* There are no significant changes in Body, testis, and epididymis weight among the control and experimental groups.
* Treatment with KH-465 increased sperm count and motility.
* Serum hormone levels of T, free T, and FSH were not significantly different in the experimental groups, while the LH level was higher than in the LHRH agonist-induced control group, but not to a significant extent.
* Levels of SOD were higher and 8-OHdG were lower in the groups that received KH-465 than in the LHRH agonist-induced control group.
Based on the results, researchers suggest, "Our results suggest that KH-465 increased sperm production via reducing oxidative stress and had a positive effect in a male infertility model".
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Ovarian Cysts And PCOS Elimination
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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Restoration of Spermatogenesis Using a New Combined Herbal Formula of Epimedium koreanum Nakai and Angelica gigas Nakai in an Luteinizing Hormone-Releasing Hormone Agonist-Induced Rat Model of Male Infertility by Hyun Jun Park, Yean Kyoung Koo, and Nam Cheol Par. (PMC)
* There are no significant changes in Body, testis, and epididymis weight among the control and experimental groups.
* Treatment with KH-465 increased sperm count and motility.
* Serum hormone levels of T, free T, and FSH were not significantly different in the experimental groups, while the LH level was higher than in the LHRH agonist-induced control group, but not to a significant extent.
* Levels of SOD were higher and 8-OHdG were lower in the groups that received KH-465 than in the LHRH agonist-induced control group.
Taken altogether, herbal Angelica alone or in combination with another herbal remedy may be used for the treatment of male infertility, pending to the confirmation of the larger sample size and multicenter human study.
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Restoration of Spermatogenesis Using a New Combined Herbal Formula of Epimedium koreanum Nakai and Angelica gigas Nakai in an Luteinizing Hormone-Releasing Hormone Agonist-Induced Rat Model of Male Infertility by Hyun Jun Park, Yean Kyoung Koo, and Nam Cheol Par. (PMC)
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