Healthy Food Onion Inhibits Risk Factors that Causes Cardiovascular Disease

By Kyle J. Norton

Cardiovascular disease (CVD) is a class of diseases associated with blood vessels caused by narrowed or blocked blood vessels that can lead to a heart attack and stroke.

The heart formed part of the circulatory system is a muscular organ pumping blood through the blood vessels to nourish the cells, tissues, and organs in the body.

Heart disease is a class of conditions associated with reduced function of the heart due to damage to the structure, including the heart muscle.

According to the statistics provided by the WHO, CVD is the number 1 cause of death globally. In other words, 31% of all global deaths are CVD.

Strokes is an emergency event caused by a blood vessel in the brain ruptures that lead to depriving oxygen in the brain cells causing the death of neurons.

According to the statistics, stroke is a leading cause of serious, long-term disability in the United States. Every year, approximately 795,000 people suffer a stroke. About 600,000 of these are first attacks, and 185,000 are recurrent attacks.

Believe it or not, 3/4 cases of stroke are in patients over 65 years of age.

There is no single cause of CVD. The most prevalent factors associated with the risk of CVD are

aging, male gender, ethnicity, smoking, metabolic syndrome including high blood pressure, sugar, and cholesterol, physical inactivity, overweight, and obesity.

However, some researchers suggested that the increased metabolic syndrome at the alarming rate correlated to the high rate of CVD onset over the past few decades probably is associated with the promotion of the Western diet in the US.

Dr. Mirmiran P, the lead scientist wrote, " Two major dietary patterns, Western and traditional, were identified. During a mean of 4.7 ± 1.4 years of follow-up, 57 participants experienced CVD-related events... In the fully adjusted model, we observed an increased risk of CVD-related events in the highest compared to the lowest tertile category of Western dietary pattern score (HR = 2.07, 95% CI = 1.03-4.18, P for trend = 0.01)

And, " the Western dietary pattern, characterized by higher loads of processed meats, salty snacks, sweets, and soft drinks, is a dietary risk factor for CVD in the Iranian population".

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures. 

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

On finding a potent ingredient that processes cardioprotection researchers examined the Allium species, their extracts, and the chemical constituents for possible effects on cardiovascular disease risk factors.

Quercetin, a type of flavonoid found in onion-induced cardioprotection against the risk factors of cardiovascular diseases, including ischemia-reperfusion injury, cardiotoxicity, and hypertension.

In patients with atherosclerotic disease, certain formulations of garlic and/or onion protected the arteries by inhibiting the formation of plaques, and other unfavorable parameters associated with the disease onset.

Garlic and onion also exerted a significant activity against blood coagulability, a condition found in patients with cardiovascular diseases.

Risk factors associated with metabolic syndromes such as hyperlipidemia, hypertension, and hyperglycemia were also inhibited by the administration of garlic and onion in vitro, vivo, and a number of small size human studies.

However, acute and chronic ingestion of large amounts of these plants or their extracts may cause liver and kidney toxicity.

Taken altogether, onion processed a higher mount of onionin A (ONA) may be considered a remedy for the prevention and treatment of cardiovascular diseases, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cardiovascular Disease: A Target for the Pharmacological Effects of Quercetin by Gormaz JG, Quintremil S, Rodrigo R. (PubMed)
(2) Garlic (Allium sativum) and onion (Allium cepa): a review of their relationship to cardiovascular disease by Kendler BS. (PubMed)
(3) Western dietary pattern increases risk of cardiovascular disease in Iranian adults: a prospective population-based study by Mirmiran P1, Bahadoran Z2, Vakili AZ3, Azizi F. (PubMed)