Herbal Artichoke Modulates the Glycemic Responses Against Elevated Level of Glucose After A Meal

By Kyle J. Norton


Glycemic response is a change in blood glucose after consuming a carbohydrate-containing food compared to Glycemic Index (GI) which is a ranking of carbohydrate-containing foods according to their effect on blood glucose levels.

Some researchers suggested that the glycemic response is the change of blood glucose after the intake of a food or meal.

Most healthy individual has normal blood glucose and insulin levels that rise within the range after eating, then return to the fasting levels over a short period of time.

According to the epidemiological studies, by controlling the glycaemic response with the healthy range, the glycaemic response can reduce the risk of type 2 diabetes.

Including additional fiber into a meal or food may have a strong implication in reducing the levels of glucose shortly after intake.

Dr. Jenkins DJ, the lead scientists in the examination of adding fiber into a meal effect in glycemic response wrote, "Addition of purified fiber to carbohydrate test meals has been shown to flatten the glycemic response in both normal and diabetic volunteers, reduce the insulin requirement in patients on the artificial pancreas and in the longer term reduce urinary glucose loss and improve diabetes control".

And, " More recently it has become clear that many aspects of carbohydrate foods (food form, antinutrients, etc.) in addition to fiber may influence the rate of digestion and has led to a classification especially of starchy foods in terms of glycemic index to define the degree to which equicarbohydrate portions of different foods raise the blood glucose".

The results strongly suggested people with abnormal levels of glycemic responses should always add some fiber to their diet to prevent the fluctuation of blood glucose before and after a meal.

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.

Researchers on the finding a natural therapeutic for the control of postprandial glycemic responses investigated the extracts from Phaseolus vulgaris and Cynara scolymus and their 1:2 combination effect on postprandial glycemia after food intake.

The study included rats given access to regular food and water, regular food, water, and a chocolate-flavored beverage, or infused with a starch bolus.

According to test assays, injection of P. vulgaris extract and the combination produced comparable reductions in intake of regular food and chocolate-flavored beverage.

Furthermore, P. vulgaris and C. scolymus extracts additively contributed to the reduction of the glycemic rise.

The finding suggested that the combination is more favorable over single extract for the treatment of postprandial glycemic responses.

Dr. the lead scientist after taking into account co and confounders said, " recent clinical use of the combination of P. vulgaris and C. scolymus extracts in the control of appetite, food intake, and postprandial glycemia".

Taken altogether, artichoke combined with kidney bean may be considered a functional formula for the treatment of patients with elevated postprandial glycemic responses with no side effects, pending to the validation of larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymusextracts on food intake and glycemia in rats by Loi B1, Fantini N, Colombo G, Gessa GL, Riva A, Bombardelli E, Morazzoni P, Carai MA. (PubMed)
(2) Dietary fiber and the glycemic response by Jenkins DJ, Jenkins AL. (PubMed)