Phytic acid (Inositol hexaphosphate) are phytichemicasl of the organic acid found abundantly in nuts, sesame seeds, soybeans, wheat, pumpkin, beans, almonds, etc.
Cancer is a class of diseases in which a group of
cells growing and multiplying disordered and uncontrollable way in our
body, have become progressively worse and damaged other healthy
tissues, sometimes spreads to other organs in the body via lymph or
blood and results may be in death.
Prostate cancer is defined as a condition in which the
cells of prostate has become cancerous, causing abnormal cell growth
which spread to the distant parts of the body. Most prostate cancers
are slow growing and enlarged prostate and prostate cancer may be
detected during the Physical (rectum) exams.
The health benefits
In prostate cancer, inositol hexaphosphate (IP6) expressed its anti
cancer effect in inhibiting the cells proliferation and induced
apoptosis through targeting the PI3K, a family of enzymes involved in
cellular functions and in multiple cellular processes pathway. Other in
the study of the same found that Inositol hexaphosphate (IP6) inhibited
both growth and proliferation and decreased cell viability of human prostate
carcinoma PC-3 cells through certain pathways, including aberrant EGF
receptor (EGFR) or IGF-1 receptor (IGF-1R) pathway in downregulation of
growth promoting and survival signaling cascades in advanced and
androgen-independent human PCa PC-3 cells.
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References
(1) Inositol hexaphosphate suppresses growth and induces apoptosis in prostate
carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway
as potential target by Gu M, Roy S, Raina K, Agarwal C, Agarwal R.(PubMed)
(2) Inositol hexaphosphate downregulates both constitutive and
ligand-induced mitogenic and cell survival signaling, and causes
caspase-mediated apoptotic death of human prostate carcinoma PC-3 cells. by Gu M, Raina K, Agarwal C, Agarwal R.(PubMed)
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