Anacardic acids are phenolic lipids, phytochemicals of the organic acid found abundantly in cashews, mangoes, etc.
Prostate cancer is defined as a condition in which the cells of
prostate has become cancerous, causing abnormal cell growth which
spread to the distant parts of the body. Most prostate cancers are slow
growing and enlarged prostate and prostate cancer may be detected
during the Physical (rectum) exams.
The health Benefits
Anacardic acid (6-pentadecylsalicylic
acid), a natural chemical constituent from ancient plant Amphipterygium
adstringens, also known as a non-specific histone acetyltransferase
inhibitor of p300, beside exhibuts its anti-inflammatory, anticancer,
antioxidative, and antimicrobial effects, but also revealed that Src
protein expression, tumor cell proliferation, and microvessel density
could be remarkably suppressed by anacardic acid and may be considered as a potent agent to treat prostate cancer. Other study of Anacardic acid (6-pentadecylsalicylic acid), also showed to inhibit of prostate cancer by down-regulates androgen receptor (AR) through suppressing p300.
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Back to Phytochemical Therapy http://kylejnorton.blogspot.ca/p/phytochemical-therapy.html
References
(1) Anacardic acid (6-pentadecylsalicylic
acid) inhibits tumor angiogenesis by targeting Src/FAK/Rho GTPases
signaling pathway by Wu Y, He L, Zhang L, Chen J, Yi Z, Zhang J, Liu M,
Pang X.(PubMed)
(2) Anacardic acid (6-pentadecylsalicylic acid) induces apoptosis of prostate cancer
cells through inhibition of androgen receptor and activation of p53
signaling by Tan J, Chen B, He L, Tang Y, Jiang Z, Yin G, Wang J, Jiang
X.(PubMed)
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