Kyle J. Norton
Digestive-tract formed part of the digestive system is a series of hollow organs joined in a long, twisting tube from the mouth to the anus and plays a critical role to absorb the nutrient from the food intake to the blood before passing them to other parts of the body.
Cancers are a class of diseases characterized by irregular cell growth in the body tissue.
Most cases of digestive tract cancer start in the cell on the surface of the inner lining of the gastrointestinal tissue before penetrating into deeper layers and colonizing the entire organ.
Colon cancer is one of the most common and slow-growing cancers in the digestive tract that
According to the statistics provided by the American Cancer Society, in 2019, 95,520 people will be diagnosed with colon cancer. Colon cancer will also cause the death of 50,260 patients in the same year.
The 5 years survival rate of colon cancer diagnosed at the localized stage is 90%.
The most common signs of digestive tract cancer include abdominal pain, blood in the stool due to bleeding, and a noticeable lump in the abdomen accompanied by the general symptoms shared with other types of cancer such as unexplained weight loss, weakness or fatigue gastrointestinal discomfort, and loss of appetite.
If you have experienced some of the aforementioned symptoms with no signs of stopping, please make sure you check with your doctor to rule out the possibility.
WHO in the examination of diet in cancer risk wrote, "Cancer is the most important cause of death after diseases of the circulatory system. It accounts for 20% of all deaths in the Region, with 2.5 million new cases diagnosed each year".
And, "A large body of literature indicates that as much as 30% of all cancer cases are linked to poor dietary habits, and is therefore preventable. The proportion reaches 70% for cancers of the gastrointestinal tract".
In other words, poor diet is one of the major causes of gastrointestinal cancer worldwide.
Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to find a potential compound for the treatment of digestive tract cancer, researchers examined the relationship between tomato intake and the risk of digestive tract cancer.
According to the data from a series of case-control studies conducted in Italy between 1983 and 1992, over the period, 317 incident cases of cancer of the oral cavity and pharynx, 85 of the esophagus, 723 of the stomach, 955 of the colon, and 629 of the rectum, were diagnosed compared to a total of 2879 controls admitted for acute, non-neoplastic conditions, unrelated to long-term modifications of diet.
The ORs for the highest tomato consumption quartile were 0.65 (95% CI 0.4-1.0) for oral cavity, pharynx, and esophagus, 0.43 (95% CI 0.3-0.6) for stomach, 0.39 (95% CI 0.3-0.5) for colon, and 0.42 (95% CI 0.3-0.6) for rectum.
The ORs of colorectal cancer for the highest consumption quintile were 0.79 (95% CI 0.6-0.9) for colon and 0.71 (95% CI 0.5-0.9) for rectal cancer, according to another study of colorectal cancer, based on 1,953 cases and 4,154 controls, conducted between 1992 and 1996, using a more detailed food frequency questionnaire.
The findings strongly suggested that a long-term high amount of tomato consumption has a strong impact on the risk of digestive tract cancer, regardless of several potential confounding factors, including measures of body mass index, calorie intake, and physical activity.
Furthermore, to examine the additional information about tomato anti-digestive-tract cancers, researchers investigated the effect of tomatoes on the risk of digestive tract tumors based on an integrated series of case-control studies conducted between 1985 and 1991 in northern Italy, where tomato intake is high but, also, heterogeneous.
For 7 years, the oral cavity and pharynx, 314; the esophagus, 85; stomach, 723; colon, 955; and rectum, 629 were diagnosed compared to a total of 2,879 controls admitted to the hospital for acute non-neoplastic or non-digestive conditions, unrelated to long-term dietary modifications.
The OR of digestive tract cancers in the upper quartile was ranging between 0.4 and 0.7 compared to the baseline.
Researchers after allowance for age, sex, study center, education, smoking, drinking level, and tertile of total caloric intake into account said, "The beneficial effect of raw tomatoes in this population may be partly since they constitute perhaps the most specific feature of the Mediterranean diet".
And, " However, if it is true that tomatoes protect against digestive tract cancers, this is of interest from both a scientific and a public health viewpoint".
Taken together, tomatoes may be considered supplements for the prevention and treatment of digestive tract cancers, pending the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Mediterranean epidemiological evidence on tomatoes and the prevention of digestive-tract cancers by La Vecchia C. (PubMed)
(2) Tomatoes and risk of digestive-tract cancers by Franceschi S1, Bidoli E, La Vecchia C, Talamini R, D'Avanzo B, Negri E. (PubMed)
(3) Cancer linked with poor nutrition by WHO
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