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Thursday, 26 October 2023

#Tomato and Its #Lycopene Protect Your Heart Against Cardiovascular Diseases through Its Effects on Blood LIpids, Blood Pressure, and Endothelial Function

Kyle J. Norton

Cardiovascular disease is a group of conditions involving blood vessels and heart.
In the Western world, most cases of CVD are related to a process called atherosclerosis, a condition associated with plaque build-up on the wall of arteries that reduces the oxygen-rich blood flow to the heart in facilitating the onset of heart disease and stroke, depending on the affected location.

Heart disease is a condition caused by plaque disruption that has induced significant heart muscle damage, leading to heart disease associated with symptoms


* Leg cramps during walking
Leg cramps during walking might be an indication of heart disease caused by arteries in your leg being clogged up by cholesterol in a result of not enough oxygen being delivered to the cells in your leg. If this symptom persists, please consult with your doctor.

* Chest pain
Chest pain is caused by blood vessels in the heart temporarily being blocked up by inadequate oxygen supply to the heart muscle. The persistence of chest pain would be an early indication of heart disease.

* Shortness of breath
Shortness of breath (dyspnea) is the major symptom of left ventricular insufficiency. People with shortness of breath are four times more likely to die from a heart disease-related cause than individuals without any symptoms.

* Headaches
People who see sparkling zigzag lines or loss of vision before a migraine attack may be at particular risk of future cardiovascular problems. Generally, headaches do not cause heart diseases but a sudden, explosive onset of great pain might be.

* Dizziness
Dizziness can have many causes including low blood count, low iron in the bloodstream and other blood disorders, dehydration, and viral illnesses. Since there are many different conditions that can produce these symptoms, anybody experiencing episodes of severe headaches or dizziness ought to be checked by your doctor.

* Palpitations
Palpitations is an extremely common symptom of heart disease. Palpitations are the skips in the heartbeats and irregular heartbeats.

* Loss of consciousness
It is a common symptom, most people pass out at least once in their lives. However, sometimes loss of consciousness indicates a dangerous or even life-threatening condition such as heart disease so when the loss of consciousness occurs it is important to figure out the cause.

Stroke is a condition caused either by reduced blood or rupture of a blood vessel depriving oxygen in the blood that induces the death of neurons.

Symptoms of a stroke attack can be
* Sudden trouble in standing
Sudden trouble in standing is an early symptom of stroke as a result of the circulation of blood that carries oxygen to the brain suddenly deplete caused by narrowing of arteries and high blood pressure.

* Dizziness and loss of balance
The brain coordinates information from the eyes, the inner ear, and the body's senses to maintain balance. If the cells of that part of the brain get damaged as the result of depleted oxygen will cause dizziness and loss of balance.

* Sudden confusion
A sudden onset of confusion means that something is potentially going wrong with the brain. Almost all conditions that affect the brain are life-threatening.

* Having trouble speaking and understanding
Having trouble speaking and understanding occurs when the brain cells in the area of the Broca, Wernicke, and angular gyrus in the left hemisphere area begin to die.

*Sudden severe headaches
Headache is a condition of pain in the head, sometimes neck or upper back pain may also be affected. It ranks amongst the most common local pain complaints and may be frequent for many people but sudden severe headaches may be caused by an early symptom of stroke due to the rupture of a brain vessel or depletion of oxygen in some parts of the brain.

* Sudden trouble seeing
This may be an early indication of stroke when the oxygen in the blood supply to the part of the brain is suddenly interrupted, affecting the cells that control the vision area of the cerebral cortex in the brain.

Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

In the urgency to discover healthy foods for the treatment of cardiovascular disease (CVD), researchers examined the effect of consuming tomato products and lycopene on markers of cardiovascular (CV) function.

By searching 3 databases including Medline, Web of Science, and Scopus from inception to August 2016, researchers identified 21 fulfilled inclusion criteria included in the meta-analyses.

All publications showed that the interventions supplementing tomato were associated with significant reductions in LDL-cholesterol, production of proinflammatory cytokine I(L-6), and improvements in flow-mediated dilation (FMD).

Compared to tomato, lycopene supplementation reduced systolic-BP (-5.66 mmHg; p = 0.002) without affecting other outcomes significantly.


Based on the results, Dr. Cheng HM, the lead scientist wrote, "The available evidence on the effects of tomato products and lycopene supplementation on CV risk factors supports the view that increasing the intake of these has positive effects on blood lipids, blood pressure, and endothelial function".

In other words, tomatoes have a potential effect on the inhibition of CVD development.

In other to review more information about tomato and its bioactive compound lycopene anti-CVD activity, researchers examined the clinical trials comparing the efficacy of lycopene supplements with tomato products on intermediate CVD risk factors.

According to the results from the clinical trial, consuming tomato-based foods is a first-line approach to cardiovascular health.

However, compared to the supplement lycopene in blood pressure management, tomato intake provided more favorable results on cardiovascular risk endpoints than did lycopene supplementation.

Taken together, tomatoes processed with a high amount of lycopene may be considered a dietary supplement for the prevention and treatment of CVD, pending to large sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis by Cheng HM1, Koutsidis G1, Lodge JK1, Ashor A2, Siervo M2, Lara J. (PubMed)
(2) Whole food versus supplement: comparing the clinical evidence of tomato intake and lycopene supplementation on cardiovascular risk factors by Burton-Freeman B, Sesso HD. (PubMed)
(3) Heart Diseases- Causes, Symptoms, Types, Preventions & Treatments by Kyle J. Norton
(4) Stroke - Causes, Symptoms The Risk Factors, Types, Preventions and Treatments by Kyle J. Norton

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