#Cinnamon Reduces Parameters Associated with the Onset of #Hyperlipidemia, According to Studies

Kyle J. Norton

Intake of cinnamon is found to improve levels of blood cholesterol in patients with Hyperlipidemia.
According to the Shaanxi Provincial People's Hospital, cinnamaldehyde (CA), an active and major compound in cinnamon reduced levels of triglyceride, cholesterol, low-density lipoprotein-cholesterol (LDL-C), and increased high-density lipoprotein-cholesterol (HDL-C), in C57BLKS/J db/db mice.

Cinnamon is a spice derived from the inner bark of a tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, used in herbal and traditional medicine as an anti-fungal and bacterial level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.


Hyperlipidemia is abnormally elevated levels of any or all lipids or lipoproteins in the blood.


Also in C57BL/Ks db/db mice study, the cinnamon extract significantly improved hyperglycemia and hyperlipidemia possibly by regulating the protein with function in medicated glucose and lipid metabolism.

Furthermore, in rats fed a high-fat diet (HFD), oral administration of cinnamon polyphenol extract reduced hyperlipidemia, inflammation, and oxidative stress by activating the proteins involved in transferring genetic information of DNA into RNA and the antioxidative defense signaling pathway.


Dr. Ghorbani A, the lead author of a joint study said, "The levels of triglyceride and total cholesterol in polyherbal mixture treated rats were significantly lower than those in the diabetic control group (P < 0.05)" and "Our results demonstrated that this polyherbal mixture has beneficial effects on blood glucose and lipid profile and it has the potential to be used as a dietary supplement for the management of diabetes"


With all the information collected, cinnamon may have potency in reducing levels of triglycerides, LDL cholesterol, and increased HDL cholesterol in patients with hyperlipidemia. Still, the use of high quantities should only be given by herbalists in the prevention of toxicity.



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Sources
(1) Antihyperglycemic and antihyperlipidemic action of cinnamaldehyde in C57BLKS/J db/db mice by Li J1, Liu T, Wang L, Guo X, Xu T, Wu L, Qin L, Sun W.(PubMed)
(2) Cinnamon Polyphenol Extract Inhibits Hyperlipidemia and Inflammation by Modulation of Transcription Factors in High-Fat Diet-Fed Rats by Tuzcu Z1, Orhan C2, Sahin N2, Juturu V3, Sahin K2.(PubMed)
(3) Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice by Kim SH1, Choung SY. (PubMed)
(4) Antihyperlipidemic effect of a polyherbal mixture in streptozotocin-induced diabetic rats by Ghorbani A1, Shafiee-Nick R2, Rakhshandeh H2, Borji A3. (PubMed)