#Chamomile Promotes Wound Healing by Increasing Wound-Breaking Strength, and Protein Collage Content, Researchers Show

Kyle J. Norton

Herbal chamomile expressed significant wound healing effect against injury and bacterial invasion induced more damage to the wound.
According to the Shiraz University of Medical Sciences, C. nobile therapy at 5% C. nobile ointment was an effective antibacterial activity and accelerated the progression of wound healing, in vivo.

Chamomile is also known as camomile, the common name of many species of daisy-like plants in the family Asteraceae, used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.

Wound healing is a natural stage of recovery of body injury.

In a Wistar male rats (210.0±4.2 g) divided into five groups: negative control group (NCG) without diabetes; positive control group (PCG) with DM (alloxan, 45 mg/kg) study, groups treated with chamomile extract optimize the healing of traumatic oral ulcers in diabetic rats through the reduction of apoptosis in the regulated immune system.

In the review of skin wound healing of phytomedicine, Dr. Pazyar N, the lead author said, " The healing process proceeds in four phases: hemostasis, inflammation, proliferation and remodeling" and " Phytomedicine presents remedies, which possess significant pharmacological effects. It is popular amongst the general population in regions all over the world. Phytotherapeutic agents have been largely used for cutaneous wound healing.....(including chamomile".

The Roskilde Universitet, in support of the wound-healing effect of chamomile, suggested the extract of M. chamomilla administered topically has wound-healing potential in the linear incisional wound, according to an animal study.

Other studies also showed that chamomile proved effective in the treatment of oral mucositis in a hamster model.

Taken together, chamomile no doubt has consisted of significant wound-healing effects by exhibiting increased wound-breaking strength, and protein collage content through topical administration.
However, well-designed clinical studies are needed to confirm the clinical efficacy of this medicine in humans.


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Sources
(1) In vivo antibacterial and wound healing activities of Roman chamomile (Chamaemelum nobile). by Kazemian H, Ghafourian S, Sadeghifard N, Badakhsh B, Heidari H1, Taji A, Shavalipour A, Mohebi R, Ebrahim-Saraie HS, Houri H, Houshmandfar R.(PubMed)
(2) TNF-alpha expression, evaluation of collagen, and TUNEL of Matricaria recutita L. extract and triamcinolone on oral ulcer in diabetic rats by Oliveira BV1, Barros Silva PG1, Nojosa Jde S2, Brizeno LA3, Ferreira JM4, Sousa FB1, Mota MR1, Alves AP1.(PubMed)
(3) Skin wound healing and phytomedicine: a review by Pazyar N1, Yaghoobi R, Rafiee E, Mehrabian A, Feily A.(PubMed)
(4) Evaluation of topical Matricaria chamomilla extract activity on linear incisional wound healing in albino rats by Jarrahi M1, Vafaei AA, Taherian AA, Miladi H, Rashidi Pour A.(PubMed)
(5) Healing action of topical chamomile on 5-fluoracil induced oral mucositis in hamster by Pavesi VC1, Lopez TC, Martins MA, Sant'Ana Filho M, Bussadori SK, Fernandes KP, Mesquita-Ferrari RA, Martins MD.(PubMed)