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Saturday, 16 September 2023

#Greentea inhibits the Risk of Chronic Inflammatory Diseases through Its Antioxidant Activity, Researchers Find

Kyle J. Norton

Good news for people with chronic inflammatory diseases, green tea polyphenols (GrTPs) is found to reduce the risk and progression of the diseases through the exhibition of potent antioxidants in regulating vital signaling pathways involved production of inflammatory cytokines. a renowned institute study suggested.

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long-term injection of large amounts may obstruct the balance of yin-yang, inducing "yin excessive syndrome" or "yang vacuity syndrome" including weakened immunity and painful cases of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger to each drink will attenuate the expression.

Chronic inflammation diseases are medical conditions caused by the overreaction of the immune system in protection against microbial invasion and damage to organs due to injury, affecting the tissue healing process, which can lead to life-long debilitation loss of tissue function, and organ failure.


According to the University of Kentucky Medical Center, green tea phytochemical polyphenols protect our body against inflammation through actions in intercepting the surge of inflammatory markers like cytokines and the production of cyclooxygenase-2 in innated anti-inflammatory cytokines.

In chronic Inflammatory Bowel Disease patients, catechin isolated from green tea enhanced the antioxidant production such as such as glutathione peroxidases (GPO) and glutathione (GSH), in significantly inhibiting excessive oxidative stress through direct or indirect in reducing the oxidative damage to the colon.


Dr. Fan FY, the lead author said, "Catechins can exert their significant anti-inflammatory properties by regulating the activation or deactivation of inflammation-related oxidative stress-related cell signaling pathways( involved proinflammation specifically)".


Particularly, the study also specified the impression of antioxidant catechin in stabilizing the structure of the gastrointestinal micro-ecological environment via promoting the proliferation of beneficial intestinal bacteria and regulating the balance of intestinal flora for induction of relief in patients with IBD.

Furthermore, in a psoriasis mouse model, BALB/c mice topically treated with IMQ for 6 consecutive days, displayed a significant alleviated psoriasiform dermatitis, improved the skin pathological structure by reducing the expression of epidermal PCNA(Base cells), and promoted the expression of caspase-14 involved in inflammation.

In fact, according to the study, the efficacy of Epigallocatechin-3-gallate (EGCG), for the treatment of
psoriasis-like inflammation is the result of the phytochemical functions in anti-inflammatory, immune regulatory, and antioxidant activation.

Taking together, green tea may be used as a protectively functional food in the prevention and treatment of chronic inflammatory diseases, but regular large amounts of injections should be avoided to prevent toxicity.


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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, healthblogs, selfgrowth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299.

Sources
(1) Chronic Inflammatory Diseases and Green Tea Polyphenols by Oz HS1. (PubMed)
(2) Catechins and Their Therapeutic Benefits to Inflammatory Bowel Disease by Fan FY1, Sang LX2, Jiang M3.(PubMed)

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