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Sunday, 3 September 2023

#Ginger Inhibits Markers Associated with the Risk of #MetabolicSyndrome and Type 2 Diabetes, Scientists Say

Kyle J. Norton

Ginger may have a potential and profound effect in regulating the expression of metabolic syndrome, some scientists suggested.

Metabolic syndrome is a cluster of conditions associated with the onset of cardiovascular disease and diabetes, including fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.

Researchers suggested that people who have 3 of 5 above conditions are at substantial risk of heart disease, stroke, and type 2 diabetes.

There is no single cause of the metabolic syndrome. some conditions epidemiologically are associated with overweight or obesity, insulin resistance, inactive lifestyle, and poor diet.

According to the statistics, In the US, approximately, over 23 percent of adults have metabolic syndrome, and many of them do not know they have it.

In fact, metabolic syndrome can be reversed through a healthy lifestyle choice, accompanied by weight loss.

Dr. Christos Pitsavos, the cardio team at the University of Athens and Society for Biomedical Diabetes Research, wrote, "Several epidemiologic studies and some clinical trials, it has been suggested that people with the metabolic syndrome may benefit from intensive lifestyle modifications including dietary changes and adopting a physically more active lifestyle."

"During the last decades increasing scientific evidence has emerged that protective health effects can be obtained from diets that are rich in fruits, vegetables, legumes, and whole grains, and which include fish, nuts, and low-fat dairy products".

These results clearly stated that by changing the poor diet pattern to a healthy one accompanied by moderate exercise, metabolic syndrome can be reserved.

Furthermore, a healthy lifestyle in patients with metabolic syndrome also greatly improves the reduction of body weight.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

With an aim to find a natural ingredient or whole food for the treatment of metabolic syndrome, researchers assess the effects of ginger (Zingiber officinale Roscoe) on type 2 diabetes mellitus (T2DM) and/or components of the metabolic syndrome (MetS) by searching the database of medical literature.

10 studies met the inclusion criteria with a total of 490 individuals included in the review.

Ginger showed a significant beneficial effect on glucose control and insulin sensitivity.

Ginger significantly reduced fasting blood glucose in T2DM patients (-21.24; 95% CI: -33.21, -9.26; P < 0.001) and three-month average plasma glucose concentration.

Furthermore, ginger also displayed significant effects of improvement of lipid profile.

Dr. Zhu J, the lead scientist said, in the final report "Based on the negligible side effects and obvious ameliorative effects on glucose control, insulin sensitivity, and lipid profile, ginger may be a promising adjuvant therapy for T2DM and MetS".

Moreover, in order to gain more evidence of ginger's anti-metabolic syndrome effect, a study to determine the individual and concomitant effect of 6-week water-based exercise and oral ginger supplement on markers that are related to metabolic syndrome and systemic inflammation in obese women with breast neoplasms was conducted the University of Mazandaran.

40 women diagnosed with breast neoplasms were randomly assigned into four groups; placebo, exercise training, ginger supplement, and exercise training+ ginger supplement groups.

Participants in the ginger supplement group and the exercise training+ ginger supplement group have orally received 4 capsules, 7 days a week and for 6 weeks.

During the experiment, the ginger supplementation and the water-based exercise have resulted in a reduction of hs-CRP, IL-10 (inflammation), insulin, glucose, insulin resistance, low-density lipoprotein (LDL), triglyceride (TG); but an increase in high-density lipoprotein (HDL) and ratio HDL/LDL.

These results strongly suggested that ginger supplement plus exercise demonstrates a significant effect in reducing the fasting glucose, insulin resistance, inflammation, and lipid profile and balancing the ratio of high and low-density lipoproteins.


In other words, the water-based exercise and ginger supplement group significantly showed a larger positive effect on all outcomes, compared to the water-based exercise or ginger supplement alone groups.

The findings suggested that obese breast neoplasm survivors' metabolic syndrome and elevated inflammation were totally inhibited by the application of ginger supplement plus exercise training.

Taken together, ginger, the pungent spice can be considered a functional food for the prevention and treatment of metabolic syndrome accompanied by moderate exercise without inducing any adverse effects.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.


Sources
(1) Effects of Ginger (Zingiber officinale Roscoe) on Type 2 Diabetes Mellitus and Components of the Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Zhu J1, Chen H1, Song Z1, Wang X1, Sun Z2. (PubMed)
(2) Individually and Combined Water-Based Exercise With Ginger Supplement, on Systemic Inflammation and Metabolic Syndrome Indices, Among the Obese Women With Breast Neoplasms by Karimi N1, Dabidi Roshan V1, Fathi Bayatiyani Z1. (PubMed)
(3) Diet, Exercise and Metabolic Syndrome by Christos Pitsavos,1 Demosthenes Panagiotakos,2 Michael Weinem,3 and Christodoulos Stefanadis. (PMC)

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